Yamaguchi Hiroshi 山口博司

… Alternative Names

Researcher Number	00450841
Other IDs
Affiliation (Current)	2020: 名古屋大学, 医学系研究科(保健), 助教
Affiliation (based on the past Project Information) *help	2016 – 2019: 名古屋大学, 医学系研究科, 特任講師 2015: 名古屋大学, 医学(系)研究科(研究院), 特任講師 2014: 秋田県立脳血管研究センター(研究局), 特命研究部1, 研究員 2012 – 2013: 秋田県立脳血管研究センター(研究局), その他部局等, 研究員 2011: 浜松医科大学, 光量子医学研究センター, 助教 2011: 秋田脳研, 放射線医学研究部, 研究員 2007 – 2009: Hamamatsu University School of Medicine, 分子イメージング先端研究センター, 特任助教
Review Section/Research Field	Principal Investigator Radiation science Except Principal Investigator Radiation science
Keywords	Principal Investigator PET / トランスポーター / イメージング / フッ素化 / 腫瘍 / 多剤耐性 / 核医学 / 分子イメージング / 脳神経疾患 / 受容体 … More Except Principal Investigator X線 / 造影剤 / X線CT / ヨウ素 / アルブミン / T4 / 核医学(PETを含む) / パーキンソン病 / 核医学 / 脳神経疾患 / セロトニントランスポーター / 運動合併症 Less

脳神経変性疾患検出を目的としたグルタミン酸トランスポーターイメージング剤の開発Principal InvestigatorOngoing
- Principal Investigator
  
  山口博司
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Nagoya University
Development of glutamate imaging agents for Epileptic severity decisionPrincipal Investigator
- Principal Investigator
  
  Yamaguchi Hiroshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Nagoya University
  秋田県立脳血管研究センター(研究部門)
Study on Derivatives of Benperidol as Imaging Agents for Dopamine D3 ReceptorPrincipal Investigator
- Principal Investigator
  
  YAMAGUCHI Hiroshi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  Research institute for Brain and Blood Vesseis Akita
Development of novel CT contrast agents with long retention in the vessel
- Principal Investigator
  
  SAKAHARA Harumi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Hamamatsu University School of Medicine
Striatal serotonergic terminals in Parkinson's disease : a PET study
- Principal Investigator
  
  MAEDA Tetsuya
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Research institute for Brain and Blood Vesseis Akita
Development of radioactive imaging medicine to detect multidrug-resistant tumorPrincipal Investigator
- Principal Investigator
  
  YAMAGUCHI Hiroshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Radiation science
- Research Institution
  Hamamatsu University School of Medicine

All 2020 2019 2018 2017 2016 2015 2013 2012 2010

All Journal Article Presentation Book

[Book] Simulated Annealing: Introduction, Applications and Theory (Chapter2 : Use of Simulated Annealing for Biophysical Analyses of Biological Macromolecular Systems)2018
- Author(s)
  Kang Jiyoung, Takuya Sumi, Hiroshi Yamaguchi, Masaru Tateno
- Total Pages
  274
- Publisher
  Nova Science Publishers
- ISBN
  9781536136746
- Data Source
  KAKENHI-PROJECT-17K10357
[Journal Article] Study on derivatives of Benperidol as imaging agents for dopamine D3 receptor2013
- Author(s)
  Hiroshi Yamaguchi, Yasuhiro Kuroda, Takashi Yamada, Hiroshi Ikenuma, Junichiro Abe, Shizuaki Murata, Kengo Ito, Kazuhiro Takahashi
- Volume
  56 (Sup.1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791350
[Journal Article] Study on derivatives of benperidol as imaging agents for dopamine D3 receptor2013
- Author(s)
  Hiroshi Yamaguchi, Yasuhiro Kuroda, Takashi Yamada, Hiroshi Ikenuma, Junichiro Abe, Shizuaki Murata, Kengo Ito, Kazuhiro Takahashi
- Journal Title
  
  Journal of Labelled compounds and Pharmaceuticals
  
  Volume: 56 (Sup.1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791350
[Presentation] PET薬剤関連研究紹介～検査から治療および教育へ～2020
- Author(s)
  山口博司
- Organizer
  日本学術振興会フッ素化学第155委員会第119回研究会
- Data Source
  KAKENHI-PROJECT-17K10357
[Presentation] 計算化学手法を用いたグルタミン酸トランスポーター結合薬剤の設計とPETイメージング剤への応用2019
- Author(s)
  山口博司, 山城敬一, 岡田真希, 軽尾友紀子, 表雅章, 舘野賢
- Organizer
  第4回トランスポーター研究会関東部会
- Data Source
  KAKENHI-PROJECT-17K10357
[Presentation] 当院における18F-タウＰＥＴイメージング剤を用いた検討～異常変性蛋白蓄積とその上流への展開～2019
- Author(s)
  山口博司
- Organizer
  フッ素化学第１５５委員会第１１５回研究会
- Data Source
  KAKENHI-PROJECT-17K10357
[Presentation] Structural design and synthesis of glutamate transporter 18F-PET Imaging agent2019
- Author(s)
  Hiroshi Yamaguchi, Takuya Sumi, JiYoung Kang, Keiichi Yamashiro, Maki Okada, Masaru Tateno
- Organizer
  International Conference on Fluorine Chemistry 2019 Himeji
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10357
[Presentation] Rational design of imaging drug as PET probe specific to glutamate transporter2019
- Author(s)
  Jiyoung Kang, Ryu-ichiro Terada, Hidekazu Yasusato, Takuya Sumi, Hiroshi Yamaguchi, Masaru Tateno
- Organizer
  International Conference on Fluorine Chemistry 2019 Himeji
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10357
[Presentation] PET薬剤の開発研究紹介～GLTイメージング剤開発を例に～2019
- Author(s)
  山口博司, 山城敬一, 軽尾友紀子, 表雅章, 舘野賢
- Organizer
  第9回フッ素化学若手の会
- Data Source
  KAKENHI-PROJECT-17K10357
[Presentation] Development of imaging agents specific to GLT excluding the off-target binding.2018
- Author(s)
  Hiroshi Yamaguchi, Takuya Sumi, Jiyoung Kang, Maki Okada, Keiichi Yamashiro, Masaru Tateno
- Organizer
  第58回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10357
[Presentation] Study on introduction of PET nuclides into glutamate transporter inhibitor.2018
- Author(s)
  Hiroshi Yamaguchi, Takuya Sumi, Jiyoung Kang, Keiichi Yamashiro, Masaru Tateno
- Organizer
  12th Congress of the World Federation of Nuclear Medicine and Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10357
[Presentation] 当院における18F-PETイメージング剤の現状とこれからの展開2018
- Author(s)
  山口博司
- Organizer
  JSPS第155委員会主催講演会「フッ素と医療の研究最前線」
- Invited
- Data Source
  KAKENHI-PROJECT-17K10357
[Presentation] Development of imaging agent for glutamic acid transporter by off-target exclusion using computational chemical method.2018
- Author(s)
  Hiroshi Yamaguchi, Takuya Sumi, Jiyoung Kang, Maki Okada, Keiichi Yamashiro, Masaru Tateno
- Organizer
  European Association of Nuclear Medicine 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10357
[Presentation] 18F-PET薬剤の開発研究から臨床検査応用まで2017
- Author(s)
  山口博司，山城敬一，鷲見拓哉，Jiyoung Kang，舘野賢
- Organizer
  第７回フッ素化学若手の会
- Data Source
  KAKENHI-PROJECT-17K10357
[Presentation] 臨床研究を目指したグルタミン酸トランスポーター阻害剤へのPET核種18F導入検討2017
- Author(s)
  山口博司，山城敬一，鷲見拓哉，Jiyoung Kang，舘野賢
- Organizer
  第40回フッ素化学討論会
- Data Source
  KAKENHI-PROJECT-17K10357
[Presentation] Development of Imaging Agents for Glutamine Transporter: In silico Binding Assay and Synthesis of Derivatives Derived from Tamoxifen and Tetrahydrobenzopyran2017
- Author(s)
  Hiroshi Yamaguchi, Takuya Sumi, Jiyoung Kang, Keiichi Yamashiro, Maki Okada, Masaru Tateno, Katsuhiko Kato, Ming-Rong Zhang, Hirohisa Watanabe, Gen Sobue
- Organizer
  22nd International Symposium on Radiopharmaceutical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10357
[Presentation] Study of Introduction PET Nuclide 18F to Glutamate Transporter Inhibitors In Silico Binding Assay and Synthesis of Derivatives Derived from Tamoxifen and Tetrahydrobenzopyran2017
- Author(s)
  Hiroshi Yamaguchi, Takuya Sumi, Jiyoung Kang, Masaru Tateno
- Organizer
  The 8th International Meering on Halogen Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10357
[Presentation] グルタミン酸代謝系PETイメージング剤の分子設計と合成検討2016
- Author(s)
  山口博司, 鷲見拓哉, Jiyoung Kang, 山城敬一, 舘野賢, 加藤克彦, 渡辺宏久, 祖父江元
- Organizer
  第３９回フッ素化学討論会
- Place of Presentation
  アバンセ（佐賀県、佐賀市）
- Year and Date
  2016-09-29
- Data Source
  KAKENHI-PROJECT-26461811
[Presentation] Enhancement of applicability of ligand-receptor docking simulation by optimizing configurational and conformational sampling spaces2016
- Author(s)
  Takuya Sumi, Hiroshi Yamaguchi, Jiyoung Kang, Masaru Tateno
- Organizer
  第５４回日本生物物理学会年会
- Place of Presentation
  つくば国際会議場（茨城県、つくば市）
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-26461811
[Presentation] グルタミン酸代謝系イメージング剤の開発検討2016
- Author(s)
  山口博司, 山城敬一, 岡田真希, 鷲見拓哉, Kang Jiyoung, 舘野賢, 張明栄, 加藤克彦, 渡辺宏久, 祖父江元
- Organizer
  第５６回日本核医学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県、名古屋市）
- Year and Date
  2016-11-03
- Data Source
  KAKENHI-PROJECT-26461811
[Presentation] Extended applicability of molecular docking simulation for ligand design by optimizing configurational and conformational sampling spaces2016
- Author(s)
  Takuya Sumi, Hiroshi Yamaguchi, Ryuichiro Terada, Jiyoung Kang, Masaru Tateno
- Organizer
  第３９回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26461811
[Presentation] Achievement of broad-range applicability of molecular docking calculation of ligand and receptor by optimizing configurational and conformational sampling spaces2016
- Author(s)
  Takuya Sumi, Hiroshi Yamaguchi, Ryuichiro Terada, Jiyoung Kang, Masaru Tateno
- Organizer
  第5回生命医薬情報学連合大会（IIBMP2016）
- Place of Presentation
  東京国際交流館プラザ平成（東京都、江東区）
- Year and Date
  2016-09-29
- Data Source
  KAKENHI-PROJECT-26461811
[Presentation] グルタミン酸代謝系イメージング剤の開発検討2015
- Author(s)
  山口博司、龍福雅恵、岡田真希、張明栄、山城敬一、加藤克彦、渡辺宏久、祖父江元
- Organizer
  第55回日本核医学会学術総会
- Place of Presentation
  ハイアットリージェンシー東京（東京都新宿区）
- Year and Date
  2015-11-05
- Data Source
  KAKENHI-PROJECT-26461811
[Presentation] 脳疾患早期発見に向けた新規放射性薬剤合成に関する研究2013
- Author(s)
  山口博司
- Organizer
  第31回メディシナルケミストリーシンポジウム
- Place of Presentation
  アステールプラザ（広島市）
- Data Source
  KAKENHI-PROJECT-24791350
[Presentation] ドパミンD3 受容体イメージング剤開発に向けてのベンペリドール誘導化2013
- Author(s)
  山口博司, 黒田康弘, 村田静昭, 茨木正信
- Organizer
  第53回日本核医学会学術総会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-24791350
[Presentation] 脳疾患早期発見に向けた新規放射性薬剤合成に関する研究2013
- Author(s)
  山口博司
- Organizer
  第31回メディシナルケミストリーシンポジウム
- Place of Presentation
  広島市
- Data Source
  KAKENHI-PROJECT-24791350
[Presentation] 認知症早期発見を目指したドパミンサブタイプイメージング剤の開発検討2013
- Author(s)
  山口博司
- Organizer
  認知症研究を知る若手研究者の集まり
- Place of Presentation
  和光純薬湯河原研修所（熱海市）
- Data Source
  KAKENHI-PROJECT-24791350
[Presentation] ドパミンD3受容体イメージング剤開発に向けてのベンペリドール誘導化2013
- Author(s)
  山口博司, 黒田康弘, 村田静昭, 茨木正信
- Organizer
  第53回日本核医学会学術総会
- Place of Presentation
  福岡国際会議場（福岡市）
- Data Source
  KAKENHI-PROJECT-24791350
[Presentation] ピペリジニル環を有したドパミンD3 受容体イメージング剤の開発2013
- Author(s)
  山口博司
- Organizer
  第43回複素環化学討論会
- Place of Presentation
  岐阜市
- Data Source
  KAKENHI-PROJECT-24791350
[Presentation] ピペリジニル環を有したドパミンD3受容体イメージング剤の開発2013
- Author(s)
  山口博司
- Organizer
  第43回複素環化学討論会
- Place of Presentation
  長良川国際会議場（岐阜市）
- Data Source
  KAKENHI-PROJECT-24791350
[Presentation] 認知症早期発見を目指したドパミンサブタイプイメージング剤の開発検討2013
- Author(s)
  山口博司
- Organizer
  認知症研究を知る若手研究者の集まり
- Place of Presentation
  熱海市
- Data Source
  KAKENHI-PROJECT-24791350
[Presentation] ドパミン受容体イメージング剤開発に向けたベンペリドール誘導化検討2012
- Author(s)
  山口博司
- Organizer
  第30回メディシナルケミストリーシンポジウム
- Place of Presentation
  タワーホール船堀（東京）
- Data Source
  KAKENHI-PROJECT-24791350
[Presentation] ドパミン受容体イメージング剤開発に向けたベンペリドール誘導化検討2012
- Author(s)
  山口博司, 黒田康弘, Kang Jiyoung, 茨木正信, 中村和浩, 舘野賢, 村田静昭
- Organizer
  第30回メディシナルケミストリーシンポジウム
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-24791350
[Presentation] [11C]Benperidol誘導体の置換基が標識条件に与える影響2012
- Author(s)
  山口博司
- Organizer
  第52回日本核医学会学術総会
- Place of Presentation
  ロイトン札幌（北海道）
- Data Source
  KAKENHI-PROJECT-24791350
[Presentation] [<11>^C]Benperidol誘導体が標識条件に与える影響2012
- Author(s)
  山口博司, 黒田康弘, 茨木正信, 中村和浩, 村田静昭, 高橋和弘
- Organizer
  第52回日本核医学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24791350
[Presentation] セロトニントランスポーターイメージング剤[11C] DASBの合成条件検討2010
- Author(s)
  工藤和彦、山口博司、茨木正信、中村和浩、松原佳亮、木下俊文、前田哲也、高橋和弘
- Organizer
  第50回日本核医学会学術総会
- Place of Presentation
  さいたま市
- Year and Date
  2010-11-11
- Data Source
  KAKENHI-PROJECT-21591585

1. 岡田真希 (00415407)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. 舘野賢 (40291926)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
3. SAKAHARA Harumi (10187031)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MAGATA Yasuhiro (20209399)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. FUCHIGAMI Takeshi (30432206)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. OGAWA Mikako (20344351)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KOJIMA Chie (50405346)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SAKAI Toshihiro (40585098)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TAKASHIMA Misato (70525592)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MAEDA Tetsuya (70359496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. KUDO Kazuhiko (70462471)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. IBARAKI Masanobu (40360359)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. NAKAMURA Kazuhiro (10312638)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. MATSUBARA Keisuke (40588430)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. KINOSHITA Toshifumi (70314599)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 龍福雅恵 (90601518)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. KANG JIYOUNG

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
18. SATO KAORU

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. OHWADA TOMOHIKO

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Yamaguchi Hiroshi 山口 博司

YAMAGUCHI Hiroshi 山口 博司

Research Projects

Research Products

Co-Researchers

脳神経変性疾患検出を目的としたグルタミン酸トランスポーターイメージング剤の開発Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of glutamate imaging agents for Epileptic severity decisionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on Derivatives of Benperidol as Imaging Agents for Dopamine D3 ReceptorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel CT contrast agents with long retention in the vessel

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Striatal serotonergic terminals in Parkinson's disease : a PET study

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of radioactive imaging medicine to detect multidrug-resistant tumorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Simulated Annealing: Introduction, Applications and Theory (Chapter2 : Use of Simulated Annealing for Biophysical Analyses of Biological Macromolecular Systems)2018

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Study on derivatives of Benperidol as imaging agents for dopamine D3 receptor2013

Author(s)

Volume

Data Source

[Journal Article] Study on derivatives of benperidol as imaging agents for dopamine D3 receptor2013

Author(s)

Journal Title

Data Source

[Presentation] PET薬剤関連研究紹介 ～検査から治療および教育へ～2020

Author(s)

Organizer

Data Source

[Presentation] 計算化学手法を用いたグルタミン酸トランスポーター結合薬剤の設計とPETイメージング剤への応用2019

Author(s)

Organizer

Data Source

[Presentation] 当院における18F-タウＰＥＴイメージング剤を用いた検討～異常変性蛋白蓄積とその上流への展開～2019

Author(s)

Organizer

Data Source

[Presentation] Structural design and synthesis of glutamate transporter 18F-PET Imaging agent2019

Author(s)

Organizer

Data Source

[Presentation] Rational design of imaging drug as PET probe specific to glutamate transporter2019

Author(s)

Organizer

Data Source

[Presentation] PET薬剤の開発研究紹介 ～GLTイメージング剤開発を例に～2019

Author(s)

Organizer

Data Source

[Presentation] Development of imaging agents specific to GLT excluding the off-target binding.2018

Yamaguchi Hiroshi 山口博司

YAMAGUCHI Hiroshi 山口博司

[Presentation] PET薬剤関連研究紹介～検査から治療および教育へ～2020

[Presentation] PET薬剤の開発研究紹介～GLTイメージング剤開発を例に～2019