Takagi Toshinori 高木俊範

… Alternative Names

TAKAGI Toshinori 高木俊範

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Researcher Number	00452152
Other IDs
Affiliation (Current)	2025: 兵庫医科大学, 医学部, 非常勤講師
Affiliation (based on the past Project Information) *help	2019 – 2021: 兵庫医科大学, 医学部, 講師 2016 – 2018: 兵庫医科大学, 医学部, 助教 2016: 岐阜大学, 医学部附属病院, 助教 2015: 岐阜大学, 医学(系)研究科(研究院), 非常勤講師 2014: 岐阜大学, 医学部附属病院, 助教 2013: 岐阜大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Neurosurgery Except Principal Investigator Neurosurgery / Basic Section 51030:Pathophysiologic neuroscience-related / Basic Section 56010:Neurosurgery-related
Keywords	Principal Investigator ヒト脂肪組織由来幹細胞 / 神経保護 / ヒト脂肪由来幹細胞 / 細胞治療 / 脳出血 / 間葉系幹細胞 / 脂肪 / 脂肪組織由来間葉系幹細胞 / 酸化ストレス / 脳血液関門 … More / 脳虚血再灌流障害 / Nrf2 / 血管内皮細胞 / 塩酸ファスジル / t-PA静注療法 … More Except Principal Investigator 細胞治療 / 脳梗塞 / 間葉系幹細胞 / 脳腫瘍幹細胞 / 移植 / 細胞移植 / 神経再生 / 幹細胞 / 羊膜 / 羊膜由来幹細胞 / 羊膜由来間葉系幹細胞 / 脳出血 / 脊椎損傷 / 傷害誘導性神経幹細胞 / 神経幹細胞 / 血管周皮細胞 / 傷害誘導性幹細胞 / 脊髄損傷 / spinal cord injury / Mesenchymal stem cell / 静脈内投与 / ヒト脂肪由来間葉系幹細胞 / 脂肪組織由来幹細胞 / 腫瘍マーカー / CXCR4 / CD56 / NCAM / CD15 / CD44 / CD133 / 脳腫瘍 / COLA1 / IGFBP7 / IDH1変異 / 悪性脳腫瘍 Less

Novel treatment for intracranial hemorrhage using amnion derived mesenchymal stem cells
- Principal Investigator
  
  Yoshimura Shinichi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Hyogo Medical University
Development of cell therapy using human-derived injury/ischemia-induced stem/progenitor cells
- Principal Investigator
  
  Nakagomi Takayuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Hyogo Medical University
human adipose-derived stem cell therapy for hemorrhagic strokePrincipal Investigator
- Principal Investigator
  
  Takagi Toshinori
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Hyogo Medical University
Nrf2 activator attenuates brain ischemia-reperfusion injury.Principal Investigator
- Principal Investigator
  
  Takagi Toshinori
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurosurgery
- Research Institution
  Hyogo Medical University
  Gifu University
human Adipose-derived stem cell therapy for cerebral ischemia
- Principal Investigator
  
  Shinichi Yoshimura
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Hyogo Medical University
Isolation of endogenous neural stem cell from spinal cord injury
- Principal Investigator
  
  KAGEYAMA HIROTO
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurosurgery
- Research Institution
  Hyogo Medical University
The possible role of IDH1 mutation, IGFBP7 and COLA1 for gliomagenesis.
- Principal Investigator
  
  SOEDA Akio
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurosurgery
- Research Institution
  Gifu University
Surface marker expressions on glioma stem cells.
- Principal Investigator
  
  OHE Naoyuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurosurgery
- Research Institution
  Gifu University
Search to the future of the IV t-PA therapyPrincipal Investigator
- Principal Investigator
  
  TAKAGI Toshinori
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurosurgery
- Research Institution
  Gifu University

All 2022 2019 2017 2016 2014

All Journal Article Presentation

[Journal Article] Early-phase administration of human amnion-derived stem cells ameliorates neurobehavioral deficits of intracerebral hemorrhage by suppressing local inflammation and apoptosis2022
- Author(s)
  Kuramoto Yoji、Fujita Mitsugu、Takagi Toshinori、Takeda Yuki、Doe Nobutaka、Yamahara Kenichi、Yoshimura Shinichi
- Journal Title
  
  Journal of Neuroinflammation
  
  Volume: 19 Issue: 1 Pages: 48-48
- DOI
  10.1186/s12974-022-02411-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09539, KAKENHI-PROJECT-20K09378
[Journal Article] Intravenous administration of human adipose-derived stem cells ameliorates motor and cognitive function for intracerebral hemorrhage mouse model2019
- Author(s)
  Kuramoto Yoji, Takagi Toshinori, Tatebayashi Kotaro, Beppu Mikiya, Doe Nobutaka, Fujita Mitsugu, & Yoshimura Shinichi
- Journal Title
  
  Brain Research
  
  Volume: 1711 Pages: 58-67
- DOI
  10.1016/j.brainres.2018.12.042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07100, KAKENHI-PROJECT-17K10854
[Journal Article] Neural regeneration by regionally induced stem cells within post-stroke brains: novel therapy perspectives for stroke patients2019
- Author(s)
  Nakagomi T, Takagi T, Beppu M, Yoshimura S, Matsuyama T
- Journal Title
  
  World journal of stem cells
  
  Volume: 11 Issue: 8 Pages: 452-463
- DOI
  10.4252/wjsc.v11.i8.452
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07380
[Journal Article] Cilostazol ameliorates collagenase-induced cerebral hemorrhage by protecting the blood brain barrier2017
- Author(s)
  Takagi T, Imai T, Mishiro K, Ishisaka M, Tsujimoto M, Ito H, Nagashima K, Matsukawa H, Tsuruma K, Shimazawa M, Yoshimura S, Kozawa O, Iwama T, Hara H.
- Journal Title
  
  J Cereb Blood Flow Metab.
  
  Volume: 37 Issue: 1 Pages: 123-139
- DOI
  10.1177/0271678x15621499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19960, KAKENHI-PROJECT-16K11325
[Journal Article] A novel nuclear factor erythroid 2-related factor 2 (Nrf2) activator RS9 attenuates brain injury after ischemia reperfusion in mice.2016
- Author(s)
  Yamauchi K, Nakano Y,Imai T, Takagi T, Tsuruma K, Shimazawa M, Iwama T, Hara H.
- Journal Title
  
  Neuroscience
  
  Volume: 333 Pages: 302-10
- DOI
  10.1016/j.neuroscience.2016.07.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19960
[Journal Article] Nrf2 activator ameliorates hemorrhagic transformation in focal cerebral ischemia under warfarin anticoagulation2016
- Author(s)
  Imai, T., Takagi, T., Kitashoji, A., Yamauchi, K., Shimazawa, M., Hara, H.
- Journal Title
  
  Neurobiology of Disease
  
  Volume: 89 Pages: 136-146
- DOI
  10.1016/j.nbd.2016.02.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19960
[Journal Article] Glycoprotein nonmetastatic melanoma protein B (GPNMB) as a novel neuroprotective factor in cerebral ischemia-reperfusion injury.2014
- Author(s)
  Nakano Y, Suzuki Y, Takagi T, Kitashoji A, Ono Y, Tsuruma K, Yoshimura S, Shimazawa M, Iwama T, Hara H
- Journal Title
  
  Neuroscience
  
  Volume: 277 Pages: 123-131
- DOI
  10.1016/j.neuroscience.2014.06.065
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25861266
[Journal Article] Early Neurologic Improvement Based on the National Institutes of Health Stroke Scale Score Predicts Favorable Outcome within 30 Minutes after Undergoing Intravenous Recombinant Tissue Plasminogen Activator Therapy.2014
- Author(s)
  Takagi T, Kato T, Sakai H, Nishimura Y
- Journal Title
  
  J Stroke Cerebrovasc dis
  
  Volume: 23 Issue: 1 Pages: 69-74
- DOI
  10.1016/j.jstrokecerebrovasdis.2012.09.013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25861266
[Journal Article] Temporal activation of Nrf2 in the penumbra and Nrf2 activator-mediated neuroprotection in ischemia-reperfusionin jury2014
- Author(s)
  Toshinori Takagi, Akira Kitashoji, Takao Iwawaki, Kazuhiro Tsuruma, Masamitsu Shimazawa, Shinichi Yoshimura, Toru Iwama, Hideaki Hara
- Journal Title
  
  Free Radic. Biol. Med.
  
  Volume: 72 Pages: 124-133
- DOI
  10.1016/j.freeradbiomed.2014.04.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390049, KAKENHI-PROJECT-25861266
[Journal Article] Diabetes mellitus aggravates hemorrhagic transformation after ischemic stroke via mitochondrial defects leading to endothelial apoptosis.2014
- Author(s)
  Mishiro K, Imai T, Sugitani S, Kitashoji A, Suzuki Y, Takagi T, Chen H, Oumi Y, Tsuruma K, Shimazawa M, Hara H
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 8 Pages: e103818-e103818
- DOI
  10.1371/journal.pone.0103818
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25861266
[Journal Article] The phosphodiesterase Ⅲ inhibitor cilostazol ameliorates ethanolinduced endothelial dysfunction.2014
- Author(s)
  Takagi T, Mishiro K, Shimazawa M, Yoshimura S, Iwama T, Hara H
- Journal Title
  
  Curr Neurovasc Res
  
  Volume: 11 Pages: 302-311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861266
[Presentation] Brain pericytes after ischemic stroke: a possible role as multipotent stem cells to differentiate into functional neurons2019
- Author(s)
  Takayuki Nakagomi, Akiko Nakano-Doi, Toshinori Takagi, Mikiya Beppu, Hideaki Nishie, Rika Sakuma, Yuki Maeda, Yusuke Minato, Nami Nakagomi, Tomohiro Matsuyama
- Organizer
  The 29rd International Symposium on Cerebral Blood Flow, Metabolism & Function (Brain & Brain PET 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07380
[Presentation] ヒト脳梗塞巣由来、脳傷害/虚血誘導性多能性幹細胞（iSCs）の細胞移植効果に関する基礎研究―iSCsを用いた臨床応用のための基礎研究2019
- Author(s)
  中込隆之、高木俊範、土居亜紀子、別府幹也、吉村紳一、松山知弘
- Organizer
  第62回日本脳循環代謝学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07380
[Presentation] Injury-induced multipotent stem cells: basic characteristics and future perspective2019
- Author(s)
  Toshinori Takagi, Mikiya Beppu, Kotaro Tatebayashi, Yoji Kuramoto, Akiko Nakano-Doi, Rika Sakuma, Takayuki Nakagomi, Tomohiro Matsuyama, Shinichi Yoshimura
- Organizer
  The 29rd International Symposium on Cerebral Blood Flow, Metabolism & Function (Brain & Brain PET 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07380

1. Shinichi Yoshimura (40240353)

# of Collaborated Projects: 6 results

# of Collaborated Products: 5 results
2. MATSUYAMA TOMOHIRO (80434950)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
3. Tatebayashi Koyaro (90759127)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 内田和孝 (10570674)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. 白川学 (50425112)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. 松山知弘 (10219529)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. KURAMOTO YOJI (10604275)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. SOEDA Akio (20444276)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 岩間亨 (20303498)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
10. 山内圭太 (10452153)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
11. 田中康恵 (30723499)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 徳田良 (70760015)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. 津田賀俊 (20759104)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. OHE Naoyuki (60362159)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KAGEYAMA HIROTO (60461068)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. BEPPU MIKIYA (00728983)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 辻本真範 (70509554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 宮居雅文 (60613502)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 矢野大仁 (00332685)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 澤田重信 (40610415)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 宮地由樹 (30737234)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 山原研一 (50450888)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. 久保秀司 (10441320)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. Hara Hideaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
25. Egashira Yusuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. Imai Takahiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
27. DOE Nobutaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 松山知宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
29. 岩脇隆夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takagi Toshinori 高木 俊範

TAKAGI Toshinori 高木 俊範

Research Projects

Research Products

Co-Researchers

Novel treatment for intracranial hemorrhage using amnion derived mesenchymal stem cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of cell therapy using human-derived injury/ischemia-induced stem/progenitor cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

human adipose-derived stem cell therapy for hemorrhagic strokePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Nrf2 activator attenuates brain ischemia-reperfusion injury.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

human Adipose-derived stem cell therapy for cerebral ischemia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Isolation of endogenous neural stem cell from spinal cord injury

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The possible role of IDH1 mutation, IGFBP7 and COLA1 for gliomagenesis.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Surface marker expressions on glioma stem cells.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Search to the future of the IV t-PA therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Early-phase administration of human amnion-derived stem cells ameliorates neurobehavioral deficits of intracerebral hemorrhage by suppressing local inflammation and apoptosis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intravenous administration of human adipose-derived stem cells ameliorates motor and cognitive function for intracerebral hemorrhage mouse model2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neural regeneration by regionally induced stem cells within post-stroke brains: novel therapy perspectives for stroke patients2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cilostazol ameliorates collagenase-induced cerebral hemorrhage by protecting the blood brain barrier2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A novel nuclear factor erythroid 2-related factor 2 (Nrf2) activator RS9 attenuates brain injury after ischemia reperfusion in mice.2016

Takagi Toshinori 高木俊範

TAKAGI Toshinori 高木俊範