SAKAMOTO Yasuo 坂本快郎

Researcher Number	00452897
Other IDs
Affiliation (based on the past Project Information) *help	2019: 熊本大学, 病院, 非常勤診療医師 2017 – 2018: 熊本大学, 医学部附属病院, 非常勤診療医師 2015 – 2016: 熊本大学, 医学部附属病院, 講師 2011 – 2014: 熊本大学, 医学部附属病院, 特任助教 2010: 熊本大学, 医学部附属病院, 医員 2008: Kumamoto University, 医学部・附属病院, 医員 2007 – 2008: Kumamoto University, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Digestive surgery Except Principal Investigator Digestive surgery / General surgery
Keywords	Principal Investigator 大腸癌 / EZH2 / JMJD3 / mir186-5p / microRNA / 肝転移 / siRNA / エピジェネティクス / p15 / オキサリプラチン … More / apoptosis / cell cycle / hPc2 / MBD1 / ポリコーム / DNAメチル化 / 分子標的治療 … More Except Principal Investigator エピジェネティクス / 大腸癌 / メチル化 / RAS 遺伝子変異 / アクチビン / アクチビン/ミオスタチン経路 / MSI status / 腫瘍局所免疫 / Activin A / 腫瘍免疫 / 骨格筋量 / Activin/Myostatin経路 / サルコペニア / カヘキシア / エピジェネティック / miRNA / 食道扁平上皮癌 / miRNA（キーワード3） / アディポサイトカイン / 肥満 / 慢性炎症 / アディポオカイン / 内臓脂肪 / 手術 / 炎症 / レプチン / アディポカイン / 内臓肥満 / pyrosequence / 予後因子 / 食道癌 / IGF2 DMR0 / トランスレーショナルリサーチ / 癌 / carcinogenesis / miR-101 / p27Kip1 / Ki67 / EZH2 / IPMN / 補助療法 / 消化器癌の発育 / 消化器癌の発生 / オートファジー Less

Comprehensive analysis of cancer cachexia signaling pathway for identifying a new therapeutic strategy in colorectal cancer.
- Principal Investigator
  
  Miyamoto Yuji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Comprehensive analysis of the relationship between DNA methylation and miRNA expression in esophageal carcinoma
- Principal Investigator
  
  SAITOU Seiya
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Development of the new treatment strategy targeting microRNA which controls histone de-methylasePrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Yasuo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Visceral obesity impacts on adipokine expression and cancer recurrence in patients with colorectal cancer
- Principal Investigator
  
  MIYAMOTO Yuji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Development of new epigenetic therapy for colon cancerPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO yasuo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Comprehensive analysis of IGF2 DMR0 methylation level in esophageal cancer
- Principal Investigator
  
  BABA Yoshifumi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Investigation into epigenetic regulatory mechanism by microRNA in carcinogenesis
- Principal Investigator
  
  TAKAMORI Hiroshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Analysis of autophagy in cancer and new strategies for cancer therapy.
- Principal Investigator
  
  HASHIMOTO Daisuke
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kumamoto University
Development of the new therapy targeting a transcriptionalsuppression mechanism by MBD1 and hPc2 in cancerPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Yasuo
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University

All 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2008 2007

All Journal Article Presentation Book

[Book] 老化および発癌のエピジェネティクス2007
- Author(s)
  丁秀鎮, 坂本快郎, 赤星慎一, 三代剛, 渡邉すぎ子, 斉藤典子, 中尾光善
- Publisher
  日高齢消医会誌
- Data Source
  KAKENHI-PROJECT-19890165
[Journal Article] 12-chemokine signature, a predictor of tumor recurrence in colorectal cancer2020
- Author(s)
  Tokunaga Ryuma、Nakagawa Shigeki、Sakamoto Yasuo、Nakamura Kenichi、Naseem Madiha、Izumi Daisuke、Kosumi Keisuke、Taki Katsunobu、Higashi Takaaki、Miyata Tatsunori、Miyamoto Yuji、Yoshida Naoya、Baba Hideo、Lenz Heinz-Josef
- Journal Title
  
  International Journal of Cancer
  
  Volume: 147(2) Issue: 2 Pages: 532-541
- DOI
  10.1002/ijc.32982
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10640, KAKENHI-PROJECT-20K16418
[Journal Article] Naples Prognostic Score Is a Useful Prognostic Marker in Patients With Metastatic Colorectal Cancer2019
- Author(s)
  Miyamoto Yuji、Hiyoshi Yukiharu、Daitoku Nobuya、Okadome Kazuo、Sakamoto Yuki、Yamashita Kohei、Kuroda Daisuke、Sawayama Hiroshi、Iwatsuki Masaaki、Baba Yoshifumi、Yoshida Naoya、Baba Hideo
- Journal Title
  
  Diseases of the Colon & Rectum
  
  Volume: 62 Issue: 12 Pages: 1485-1493
- DOI
  10.1097/dcr.0000000000001484
- Data Source
  KAKENHI-PROJECT-17K10640
[Journal Article] Low Visceral Fat Content Is a Negative Predictive Marker for Bevacizumab in Metastatic Colorectal Cancer.2018
- Author(s)
  Miyamoto Y, Oki E, Emi Y, Tokunaga S, Shimokawa M, Ogata Y, Akagi Y, Sakamoto Y, Tanaka T, Saeki H, Maehara Y, Baba H.
- Journal Title
  
  Anticancer Res.
  
  Volume: 38(1) Issue: 1 Pages: 491-499
- DOI
  10.21873/anticanres.12249
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10640
[Journal Article] Low Visceral Fat Content Is a Negative Predictive Marker for Bevacizumab in Metastatic Colorectal Cancer2018
- Author(s)
  Miyamoto Y, Oki E, Emi Y, Tokunaga S, Shimokawa M, Ogata Y, Akagi Y, Sakamoto Y, Tanaka T, Saeki H, Maehara Y, Baba H.
- Journal Title
  
  Anticancer Res.
  
  Volume: 38(1) Pages: 491-499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10640
[Journal Article] Comparison of systemic inflammatory and nutritional scores in colorectal cancer patients who underwent potentially curative resection.2017
- Author(s)
  Tokunaga R, Sakamoto Y, Nakagawa S, Izumi D, Kosumi K, Taki K, Higashi T, Miyata T, Miyamoto Y, Yoshida N, Baba H.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: in press Issue: 4 Pages: 740-748
- DOI
  10.1007/s10147-017-1102-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462020, KAKENHI-PROJECT-17K10640, KAKENHI-PROJECT-16K19943, KAKENHI-PROJECT-16K19941
[Journal Article] The Prognostic Significance of Histone Lysine Demethylase JMJD3/KDM6B in Colorectal Cancer.2016
- Author(s)
  Tokunaga R, Sakamoto Y, Nakagawa S, Miyake K, Izumi D, Kosumi K, Taki K, Higashi T, Imamura Y, Ishimoto T, Iwatsuki M, Baba Y, Miyamoto Y, Yoshida N, Oki E, Watanabe M, Baba H.
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 23(2) Issue: 2 Pages: 678-85
- DOI
  10.1245/s10434-015-4879-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10157, KAKENHI-PROJECT-15K10142, KAKENHI-PROJECT-16K19943
[Journal Article] Retroileal colorectal anastomosis after extended left colectomy: application for laparoscopic surgery.2016
- Author(s)
  Sakamoto Y, Tokunaga R, Miyamoto Y, Ohuchi M, Nakamura K, Kosumi K, Harada K, Shigaki H, Kurashige J, Iwatsuki M, Baba Y, Yoshida N, Baba H.
- Journal Title
  
  Surg Today.
  
  Volume: 46(12) Issue: 12 Pages: 1476-1478
- DOI
  10.1007/s00595-016-1313-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10142, KAKENHI-PROJECT-16K19943
[Journal Article] Omental flap after pelvic exenteration for pelvic cancer.2016
- Author(s)
  Miyamoto Y, Akiyama T, Sakamoto Y, Tokunaga R, Ohuchi M, Shigaki H, Kurashige J, Iwatsuki M, Baba Y, Yoshida N, Baba H.
- Journal Title
  
  Surg Today
  
  Volume: 46(12) Issue: 12 Pages: 1471-1475
- DOI
  10.1007/s00595-016-1348-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462020, KAKENHI-PROJECT-16K19943
[Journal Article] Negative Impact of Skeletal Muscle Loss after Systemic Chemotherapy in Patients with Unresectable Colorectal Cancer.2015
- Author(s)
  Miyamoto Y, Baba Y, Sakamoto Y, Ohuchi M, Tokunaga R, Kurashige J, Hiyoshi Y, Iwagami S, Yoshida N, Watanabe M, Baba H.
- Journal Title
  
  PLoS One
  
  Volume: 10(6) Issue: 6 Pages: e0129742-e0129742
- DOI
  10.1371/journal.pone.0129742
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462020
[Journal Article] Perioperative chemotherapy and hepatic resection for resectable colorectal liver metastases2015
- Author(s)
  Beppu T, Sakamoto Y, Hayashi H, Baba H
- Journal Title
  
  Hepatobiliary Surg Nutr
  
  Volume: 4 Pages: 72-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591977
[Journal Article] Low Visceral Fat Content is Associated with Poor Prognosis in a Database of 507 Upper Gastrointestinal Cancers.2015
- Author(s)
  Harada K, Baba Y, Ishimoto T, Kosumi K, Tokunaga R, Izumi D, Ida S, Imamura Y, Iwagami S, Miyamoto Y, Sakamoto Y, Yoshida N, Watanabe M, Baba H.
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 22(12) Issue: 12 Pages: 3946-53
- DOI
  10.1245/s10434-015-4432-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462020
[Journal Article] Prognostic Nutritional Index Predicts Severe Complications, Recurrence, and Poor Prognosis in Patients With Colorectal Cancer Undergoing Primary Tumor Resection.2015
- Author(s)
  Tokunaga R, Sakamoto Y, Nakagawa S, Miyamoto Y, Yoshida N, Oki E, Watanabe M, Baba H
- Journal Title
  
  Dis Colon Rectum
  
  Volume: 58(11) Issue: 11 Pages: 1048-57
- DOI
  10.1097/dcr.0000000000000458
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462020
[Journal Article] Post-chemotherapeutic CEA and CA19-9 Are Prognostic Factors in Patients with Colorectal Liver Metastases Treated with Hepatic Resection After Oxaliplatin-based Chemotherapy2015
- Author(s)
  Sakamoto Y, Miyamoto Y, Beppu T, Nitta H, Imai K, Hayashi H, Baba Y, Yoshida N, Chikamoto A, Baba H
- Journal Title
  
  Anticancer Res
  
  Volume: 35 Pages: 2359-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591977
[Journal Article] Suppressor microRNA-145 Is Epigenetically Regulated by Promoter Hypermethylation in Esophageal Squamous Cell Carcinoma.2015
- Author(s)
  Harada K, Baba Y, Ishimoto T, Kosumi K, Tokunaga R, Izumi D, Ohuchi M, Nakamura K, Kiyozumi Y, Kurashige J, Iwagami S, Miyamoto Y, Sakamoto Y, Yoshida N, Oki E, Watanabe M, Baba H.
- Journal Title
  
  Anticancer Res
  
  Volume: 35(9) Pages: 4617-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10104
[Journal Article] Sarcopenia is a Negative Prognostic Factor After Curative Resection of Colorectal Cancer.2015
- Author(s)
  Miyamoto Y, Baba Y, Sakamoto Y, Ohuchi M, Tokunaga R, Kurashige J, Hiyoshi Y, Iwagami S, Yoshida N, Yoshida M, Watanabe M, Baba H.
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 22(8) Issue: 8 Pages: 2663-8
- DOI
  10.1245/s10434-014-4281-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462020
[Journal Article] Chemotherapy and targeted therapy for patients with initially unresectable colorectal liver metastases, focusing on conversion hepatectomy and long-term survival2014
- Author(s)
  Beppu T, Miyamoto Y(equal contributor), Sakamoto Y, Imai K, Nitta H, Hayashi H, Chikamoto A, Watanabe M, Ishiko T, Baba H.
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 21 Suppl 3 Issue: S3 Pages: 405-13
- DOI
  10.1245/s10434-014-3577-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591966, KAKENHI-PROJECT-25670588, KAKENHI-PROJECT-26460867, KAKENHI-PROJECT-26462020
[Journal Article] Angiopoietin-like protein 2 renders colorectal cancer cells resistant to chemotherapy by activating spleen tyrosine kinase-phosphoinositide 3-kinase-dependent anti-apoptotic signaling.2014
- Author(s)
  Horiguchi H, Endo M, Miyamoto Y, Sakamoto Y, Odagiri H, Masuda T, Kadomatsu T, Tanoue H, Motokawa I, Terada K, Morioka MS, Manabe I, Baba H, Oike Y.
- Journal Title
  
  Cancer Science
  
  Volume: 105 Issue: 12 Pages: 1550-1559
- DOI
  10.1111/cas.12554
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461192, KAKENHI-PROJECT-25870543, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26462020, KAKENHI-PROJECT-26670405, KAKENHI-PROJECT-26861050
[Journal Article] Efficacy of S-1 in colorectal cancer2014
- Author(s)
  Miyamoto Y, Sakamoto Y, Yoshida N, Baba H
- Journal Title
  
  Expert Opin Pharmacother
  
  Volume: 15 Issue: 12 Pages: 1761-70
- DOI
  10.1517/14656566.2014.937706
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670588, KAKENHI-PROJECT-26462020
[Journal Article] Evaluation of the necessity of primary tumor resection for synchronous metastatic colorectal cancer2014
- Author(s)
  Miyamoto Y, Watanabe M, Sakamoto Y, Shigaki H, Murata A, Sugihara H, Eto K, Ishimoto T, Iwatsuki M, Baba Y, Iwagami S, Yoshida N, Baba H
- Journal Title
  
  Surg Today
  
  Volume: 44 Issue: 12 Pages: 2287-92
- DOI
  10.1007/s00595-014-0869-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591977
[Journal Article] Methylation levels of LINE-1 in primary lesion and matched metastatic lesions of colorectal cancer.2013
- Author(s)
  Murata A, Baba Y, Watanabe M, Shigaki H, Miyake K, Ishimoto T, Iwatsuki M, Iwagami S, Sakamoto Y, Miyamoto Y, Yoshida N, Nosho K, Baba H.
- Journal Title
  
  Br J Cancer.
  
  Volume: 109 Issue: 2 Pages: 408-415
- DOI
  10.1038/bjc.2013.289
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591941, KAKENHI-PROJECT-24659617, KAKENHI-PROJECT-25670588
[Journal Article] A nomogram predicting disease-free survival in patients with colorectal liver metastases treated with hepatic resection : multicenter data collection as a Project Study for Hepatic Surgery of the Japanese Society of Hepato-Biliary- Pancreatic Surgery2012
- Author(s)
  Beppu T, Sakamoto Y, Hasegawa K, Honda G, Tanaka K, Kotera Y, Nitta H, Yoshidome H, Hatano E, Ueno M, Takamura H, Baba H, Kosuge T, Kokudo N, Takahashi K, Endo I, Wakabayashi G, Miyazaki M, Uemoto S, Ohta T, Kikuchi K, Yamaue H, Yamamoto M, Takada T.
- Journal Title
  
  J Hepatobiliary Pancreat Sci.
  
  Volume: 19(1) Issue: 1 Pages: 72-84
- DOI
  10.1007/s00534-011-0460-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592015
[Journal Article] Primary malignant melanoma of the esophagus with extensive intraepithelial extension2012
- Author(s)
  Inadomi K, Ishimoto T, Watanabe M, Iwatsuki M, Arima K, Ida S, Nagai Y, Iwagami S, Baba Y, Sakamoto Y, Miyamoto Y, Honda Y, Iyama K, Baba H.
- Journal Title
  
  Ann Thorac Surg
  
  Volume: 94(6) Issue: 6 Pages: 2105-7
- DOI
  10.1016/j.athoracsur.2012.04.127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592015
[Journal Article] Safe laparoscopic resection of a gastric gastrointestinal stromal tumor close to the esophagogastric junction2012
- Author(s)
  Sakamoto Y, Sakaguchi Y, Akimoto H, Chinen Y, Kojo M, Sugiyama M, Morita K, Saeki H, Minami K, Soejima Y, Toh Y, Okamura T.
- Journal Title
  
  Surg Today
  
  Volume: 42(7) Issue: 7 Pages: 708-11
- DOI
  10.1007/s00595-012-0121-0
- NAID
  10030788460
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592015
[Journal Article] A safe procedure of laparoscopic resection for gastric GIST close to the esophagogastric junction.2012
- Author(s)
  Sakamoto Y
- Journal Title
  
  Surg Today
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592015
[Journal Article] Pyrosequencing assay to measure LINE-1 methylation level in esophageal squamous cell carcinoma2012
- Author(s)
  Iwagami S, Baba Y, Watanabe M, Shigaki H, Miyake K, Ida S, Nagai Y, Ishimoto T, Iwatsuki M, Sakamoto Y, Miyamoto Y, Baba H.
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 19(8) Issue: 8 Pages: 2726-32
- DOI
  10.1245/s10434-011-2176-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592015, KAKENHI-PROJECT-23689061, KAKENHI-PROJECT-24659617
[Journal Article] 大腸癌発癌におけるSPINK1の発現と意義2011
- Author(s)
  井田智、宮本裕士、坂本快郎、渡邊雅之、馬場秀夫
- Journal Title
  
  消化器内科
  
  Volume: 53(6) Pages: 627-631
- URL
  http://www.kahyo.com/item/SH201112-536
- Data Source
  KAKENHI-PROJECT-23592015
[Journal Article] Sunitinibが著効したimatinib耐性GISTの１例-2011
- Author(s)
  坂本快郎
- Journal Title
  
  癌と化学療法
  
  Volume: 38 Pages: 827-830
- Data Source
  KAKENHI-PROJECT-23592015
[Journal Article] Feeding tube insertion through the round ligament of liver : a safe approach to placing a feeding tube for retrosternal gastric tube reconstruction after esophagectomy2011
- Author(s)
  Watanabe M, Etoh K, Nagai Y, Baba Y, Iwatsuki M, Ishimoto T, Sakamoto Y, Miyamoto Y, Yoshida N, Baba H.
- Journal Title
  
  J Am Coll Surg
  
  Volume: 213(5) Issue: 5 Pages: e21-e22
- DOI
  10.1016/j.jamcollsurg.2011.08.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592015
[Journal Article] Sunitinibが著効したimatinib耐性GISTの1例-2011
- Author(s)
  坂本快郎、秋元寿文、河野浩幸、知念順樹、森田和豊、杉山雅彦、佐伯浩司、南一仁、副島雄二、坂口善久、藤也寸志、岡村健
- Journal Title
  
  癌と化学療法
  
  Volume: 38 Pages: 827-830
- URL
  http://www.ncbi.nlm.nih.gov/pubmed?cmd=search&orig_db=PubMed&term=0385-0684%5Bis%5D%20AND%202011%5Bdp%5D%20AND%20827%5Bpg%5D&doptcmdl=Abstract
- Data Source
  KAKENHI-PROJECT-23592015
[Journal Article] 臓器別薬物療法3.食道癌1)術前療法2011
- Author(s)
  馬場祥史、渡邊雅之、小澄敬祐、井田智、長井洋平、石本崇胤、岩槻政晃、岩上志朗、坂本快郎、宮本裕士、馬場秀夫
- Journal Title
  
  臨床外科
  
  Volume: 66 Pages: 86-90
- URL
  http://medicalfinder.jp/ejournal/1407103786.html?
- Data Source
  KAKENHI-PROJECT-23592015
[Journal Article] Feasibility of Delta-Shaped Anastomoses in Totally Laparoscopic Distal Gastrectomy2011
- Author(s)
  Oki E., et al
- Journal Title
  
  Eur Surg Res
  
  Volume: 47 Issue: 4 Pages: 205-10
- DOI
  10.1159/000332850
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249072, KAKENHI-PROJECT-22659246, KAKENHI-PROJECT-23592015
[Journal Article] Detection of liver metastases secondary to pancreatic cancer : utility of combined helical computed tomography during arterial portography with biphasic computed tomography-assisted hepatic arteriography.2010
- Author(s)
  Ikuta Y, Takamori H, Ikeda O, Tanaka T, Sakamoto Y, Hashimoto D, Ozaki N, Nakahara O, Furuhashi S, Abe S, Beppu T, Shimada S, Yamashita Y, Baba H.
- Journal Title
  
  J Gastroenterol 45(12)
  
  Pages: 1241-1246
- NAID
  10027700141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20599013
[Journal Article] Can the Estimation of Physiologic Ability and Surgical Stress (E-PASS) scoring system predict operative morbidity after distal pancreatectomy?2010
- Author(s)
  Hashimoto D, Takamori H, Sakamoto Y, Tanaka H, Hirota M, Baba H.
- Journal Title
  
  Surgery Today 40(7)
  
  Pages: 632-637
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20599013
[Journal Article] Is Estimation of physiologic ability and surgical stress (E-PASS) able to predict operative morbidity after pancreaticoduodenectomy?2010
- Author(s)
  Hashimoto D, Takamori H, Sakamoto Y, Ikuta Y, Nakahara O, Furuhashi S, Tanaka H, Watanabe M, Beppu T, Hirota M, Baba H.
- Journal Title
  
  J Hepatobiliary Pancreat Sci. 17(2)
  
  Pages: 132-138
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20599013
[Journal Article] Polycomb group protein-associated chromatin is reproduced in post-mitotic G1 phase and is required for S phase progression2008
- Author(s)
  Aoto T, Saitoh N, Sakamoto Y, Watanabe S, Nakao M.
- Journal Title
  
  J Biol Chem 283
  
  Pages: 18905-15
- Data Source
  KAKENHI-PROJECT-19890165
[Journal Article] Overlapping roles of the methylated DNA-binding protein MBD1 and polycombgroup proteins in transcriptional repression of HOXA genes and heterochromatin foci formation2007
- Author(s)
  Sakamoto Y, Watanabe S, Ichimura T, Kawasuji M, Koseki H, Baba H, Nakao M
- Journal Title
  
  J Biol Chem 283
  
  Pages: 16391-400
- Data Source
  KAKENHI-PROJECT-19890165
[Presentation] 大腸癌患者におけるカヘキシア関連分子Activin A発現の臨床的意義2019
- Author(s)
  1.大徳　暢哉、宮本　裕士、坂本　悠樹、江藤　弘二郎、日吉　幸晴、長井　洋平、石本　崇胤、馬場　祥史、岩上　志朗、吉田　直矢、馬場　秀夫
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-17K10640
[Presentation] 大腸癌におけるPNIおよび腫瘍内CD8陽性T細胞と予後の関連2019
- Author(s)
  2.大徳　暢哉、宮本　裕士、坂本　悠樹、日吉　幸晴、石本　崇胤、岩槻　政晃、馬場　祥史、岩上　志朗、吉田　直矢、馬場　秀夫
- Organizer
  第74回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-17K10640
[Presentation] 腸癌における腫瘍内CD3、CD8陽性T細胞の臨床的意義2019
- Author(s)
  3.大徳　暢哉、宮本　裕士、秋山　貴彦、坂本　悠樹、江藤　弘二郎、日吉　幸晴、長井　洋平、岩槻　政晃、馬場　祥史、岩上　志朗、吉田　直矢、馬場　秀夫
- Organizer
  第74回日本大腸肛門病学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10640
[Presentation] アクチビンAは大腸癌患者の予後予測因子となりうる2018
- Author(s)
  大徳暢哉、宮本裕士、坂本悠樹、江藤弘二郎、日吉幸晴、長井洋平、石本崇胤、馬場祥史、岩上志朗、吉田直矢、馬場秀夫
- Organizer
  第29回日本消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-17K10640
[Presentation] 腫瘍におけるアクチビンAの発現は大腸癌患者の予後と関連している2018
- Author(s)
  Nobuya Daitoku、Yuji Miyamoto, Yuki Sakamoto, Kojiro Eto, Yukiharu Hiyoshi, Masaaki Iwatsuki, Takatsugu Ishimoto, Yoshifumi Baba, Shiro Iwagami, Naoya Yoshida, Hideo Baba
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10640
[Presentation] 大腸癌切除症例において術後合併症が予後に与える影響2017
- Author(s)
  宮本裕士、日吉幸晴、坂本快郎、澤山　浩、岩槻政晃、馬場祥史、吉田直矢、馬場秀夫
- Organizer
  JDDW 2017
- Data Source
  KAKENHI-PROJECT-15K10142
[Presentation] 内臓肥満が大腸癌に与える影響：Leptinは女性の大腸癌予後を悪化させる。2017
- Author(s)
  宮本裕士、大内繭子、坂本快郎、徳永竜馬、澤山浩、岩槻政晃、馬場祥史、吉田直矢、馬場秀夫
- Organizer
  日本消化器外科学会総会　2017
- Data Source
  KAKENHI-PROJECT-17K10640
[Presentation] 腹腔鏡下前方切除術における縫合不全予防のための工夫2017
- Author(s)
  坂本快郎、大内繭子、内原智幸、問端　輔、八木泰佑、中村健一、美馬浩介、澤山　浩、木下浩一、岩槻政晃、馬場祥史、吉田直矢、馬場秀夫
- Organizer
  第86回大腸癌研究会
- Data Source
  KAKENHI-PROJECT-15K10142
[Presentation] 内臓肥満が大腸癌に与える影響: Leptinは女性の大腸癌予後を悪化させる2017
- Author(s)
  宮本裕士、大内繭子、坂本快郎、徳永竜馬、織田枝里、澤山　浩、岩槻政晃、馬場祥史、吉田直矢、馬場秀夫
- Organizer
  第72回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-15K10142
[Presentation] 大腸癌における内臓脂肪とレプチンによる炎症の関連性2016
- Author(s)
  大内　繭子、宮本　裕士、織田　枝里、内原　智幸、問端　輔、八木　泰祐、黒田　大介、江藤　二男、中村　健一、徳永　竜馬、美馬　浩介、木下　浩一、岩槻　政晃、馬場　祥史、坂本　快郎、吉田　直矢、馬場　秀夫.
- Organizer
  第27回日本消化器癌発生学会総会
- Place of Presentation
  城山観光ホテル（鹿児島県）
- Data Source
  KAKENHI-PROJECT-26462020
[Presentation] 大腸癌における腹腔内脂肪量とアディポサイトカインの関連2015
- Author(s)
  大内繭子、宮本裕士、清住雄希、中村健一、泉大輔、小澄敬祐、徳永竜馬、江藤弘二朗、杉原栄孝、原田和人、蔵重淳二、日吉幸晴、岩上志朗、馬場祥史、坂本快郎、吉田直矢、馬場秀夫
- Organizer
  第115回日本外科学会定期学術集会
- Place of Presentation
  名古屋国際会議場（愛知県）
- Year and Date
  2015-04-18
- Data Source
  KAKENHI-PROJECT-26462020
[Presentation] Methylation levels of LINE-1 in primary lesion and matched metastatic lesions of colorectal cancer2013
- Author(s)
  Murata A, Baba Y, Watanabe M, Shigaki H, Iwagami S, Sakamoto Y, Miyamoto Y, Baba H
- Organizer
  AACR Annual Meeting 2013
- Place of Presentation
  Washington, DC, USA
- Year and Date
  2013-04-09
- Data Source
  KAKENHI-PROJECT-24659617
[Presentation] Hypomethylation of the IGF2 DMR0 in Esophageal Squamous Cell Carcinoma, Detected by Bisulfite Pyrosequencing, is Associated with Poor Prognosis2013
- Author(s)
  Murata A, Baba Y, Watanabe M, Shigaki H, Miyake K, Ozaki N, Ishimoto T, Iwatsuki M, Iwagami S, Sakamoto Y, Miyamoto Y, Yoshida N, Baba H
- Organizer
  9th AACR-Japanese Cancer Association Joint Conference (AACR-JCA)
- Place of Presentation
  Hyatt Regency Maui, Hawaii
- Year and Date
  2013-02-23
- Data Source
  KAKENHI-PROJECT-24659617
[Presentation] Clinical and prognostic significance of LINE-1metastases from cororectal cancer2013
- Author(s)
  Baba Y, Watanabe M, Murata A, Shigaki H, Iwagami S, Sakamoto Y, Miyamoto Y, Beppu T, Baba H
- Organizer
  9th AACR-Japanese Cancer Association Joint Conference (AACR-JCA)
- Place of Presentation
  Hyatt Regency Maui, Hawaii
- Year and Date
  2013-02-23
- Data Source
  KAKENHI-PROJECT-24659617
[Presentation] 食道扁平上皮癌におけるIGF2 DMR0メチル化レベルと予後の関係2013
- Author(s)
  村田飛鳥、馬場祥史、渡邊雅之、志垣博信、石本崇胤、岩槻政晃、尾崎宣之、岩上志朗、坂本快郎、宮本裕士、吉田直矢、馬場秀夫
- Organizer
  第113回日本外科学会学術集会
- Place of Presentation
  マリンメッセ福岡
- Year and Date
  2013-04-13
- Data Source
  KAKENHI-PROJECT-24659617
[Presentation] 大腸癌原発巣と転移巣におけるLINE-1メチル化レベルの比較2013
- Author(s)
  村田飛鳥、馬場祥史、渡邊雅之、志垣博信、岩上志朗、坂本快郎、宮本裕士、別府透、馬場秀夫
- Organizer
  第24回日本消化器癌発生学会
- Place of Presentation
  石川県立音楽堂
- Year and Date
  2013-09-06
- Data Source
  KAKENHI-PROJECT-24659617
[Presentation] 大腸切除術を施行した腹膜播種を伴う大腸癌症例の検討2012
- Author(s)
  坂本快郎
- Organizer
  第76回大腸癌研究会
- Place of Presentation
  栃木　栃木県総合文化センター
- Data Source
  KAKENHI-PROJECT-23592015
[Presentation] 大腸切除術を施行した腹膜播種を伴う大腸癌症例の検討2012
- Author(s)
  坂本快郎
- Organizer
  第76回大腸癌研究会
- Place of Presentation
  栃木県総合文化センター
- Year and Date
  2012-01-20
- Data Source
  KAKENHI-PROJECT-23592015
[Presentation] 大腸癌の発育進展におけるEZH2発現の意義2012
- Author(s)
  坂本快郎
- Organizer
  第27回日本消化器癌発生学会
- Place of Presentation
  徳島ルネッサンスリゾートナルト
- Data Source
  KAKENHI-PROJECT-24591977
[Presentation] 大腸癌肝・肺転移に対する外科的治療成績に関する検討2011
- Author(s)
  坂本快郎
- Organizer
  第66回日本消化器外科学会総会
- Place of Presentation
  名古屋　名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23592015
[Presentation] 大腸癌肝・肺転移に対する外科的治療成績に関する検討2011
- Author(s)
  坂本快郎
- Organizer
  第66回日本消化器外科学会総会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-07-15
- Data Source
  KAKENHI-PROJECT-23592015
[Presentation] 直腸癌イレウス症例に対する人工肛門造設術先行・二期的腹腔鏡補助下直腸切除術2011
- Author(s)
  坂本快郎
- Organizer
  第24回日本内視鏡外科学会総会
- Place of Presentation
  大阪　グランキューブ大阪
- Data Source
  KAKENHI-PROJECT-23592015
[Presentation] 直腸癌イレウス症例に対する人工肛門造設術先行・二期的腹腔鏡補助下直腸切除術2011
- Author(s)
  坂本快郎
- Organizer
  第24回日本内視鏡
- Place of Presentation
  合歓の郷- Hotel&Resort -(三重県)
- Year and Date
  2011-12-01
- Data Source
  KAKENHI-PROJECT-23592015
[Presentation] 家族性大腸腺腫症に対する腹腔鏡下大腸全摘術の経験2011
- Author(s)
  坂本快郎
- Organizer
  熊本内視鏡外科フォーラム
- Place of Presentation
  熊本　ホテル日航熊本
- Data Source
  KAKENHI-PROJECT-23592015
[Presentation] 家族性大腸腺腫症に対する腹腔鏡下大腸全摘術の経験2011
- Author(s)
  坂本快郎
- Organizer
  熊本内視鏡外科フォーラム
- Place of Presentation
  ホテル日航熊本
- Year and Date
  2011-11-02
- Data Source
  KAKENHI-PROJECT-23592015
[Presentation] 癌細胞のHOXA遺伝子群の抑制とヘテロクロマチン形成におけるMBD1とポリコームタンパク質群の協調的な役割2007
- Author(s)
  坂本快郎
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19890165

1. MIYAMOTO Yuji (80551259)

# of Collaborated Projects: 5 results

# of Collaborated Products: 25 results
2. BABA Yoshifumi (20599708)

# of Collaborated Projects: 3 results

# of Collaborated Products: 23 results
3. OHMURAYA Masaki (60398229)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. ISHIMOTO Takatsugu (00594889)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
5. HASHIMOTO Daisuke (80508507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. BABA Hideo (20240905)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
7. TANAKA Hiroshi (70452901)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. OZAKI Nobuyuki (40551255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. TAKAMORI Hiroshi (90363514)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. NAKAHARA Osamu (40583042)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. HORINO Kei (60452900)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. HAYASHI Naoko (20452899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. BEPPU Toru (70301372)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. WATANABE Masayuki (80254639)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. IWAGAMI Shiro (70530153)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
16. SAITOU Seiya (00594475)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 今村裕 (70583045)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
18. 井田智 (80583038)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
19. 林洋光 (80625773)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. ENDO Motoyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 岩槻政晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SAKAMOTO Yasuo 坂本 快郎

Research Projects

Research Products

Co-Researchers

Comprehensive analysis of cancer cachexia signaling pathway for identifying a new therapeutic strategy in colorectal cancer.

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Comprehensive analysis of the relationship between DNA methylation and miRNA expression in esophageal carcinoma

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Development of the new treatment strategy targeting microRNA which controls histone de-methylasePrincipal Investigator

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Visceral obesity impacts on adipokine expression and cancer recurrence in patients with colorectal cancer

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Development of new epigenetic therapy for colon cancerPrincipal Investigator

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Comprehensive analysis of IGF2 DMR0 methylation level in esophageal cancer

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Investigation into epigenetic regulatory mechanism by microRNA in carcinogenesis

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Analysis of autophagy in cancer and new strategies for cancer therapy.

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Development of the new therapy targeting a transcriptionalsuppression mechanism by MBD1 and hPc2 in cancerPrincipal Investigator

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[Book] 老化および発癌のエピジェネティクス2007

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[Journal Article] 12-chemokine signature, a predictor of tumor recurrence in colorectal cancer2020

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[Journal Article] Naples Prognostic Score Is a Useful Prognostic Marker in Patients With Metastatic Colorectal Cancer2019

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[Journal Article] Low Visceral Fat Content Is a Negative Predictive Marker for Bevacizumab in Metastatic Colorectal Cancer.2018

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[Journal Article] Low Visceral Fat Content Is a Negative Predictive Marker for Bevacizumab in Metastatic Colorectal Cancer2018

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SAKAMOTO Yasuo 坂本快郎