WATANABE Takuya 渡部琢哉

Researcher Number	00455643
Affiliation (based on the past Project Information) *help	2010: Hokkaido University, 大学院・医学研究科, 客員研究員 2009: Hokkaido University, 大学病院, 助教
Review Section/Research Field	Principal Investigator Orthopaedic surgery
Keywords	Principal Investigator 破骨細胞 / 腫瘍微小環境 / RANKL / 骨浸潤 / VEGF / Srcファミリーキナーゼ / 骨転移 / 腫瘍血管新生 / 軟部腫瘍学 / 骨

Research Projects
(1 results)
Research Products
(14 results)

Elucidation of the mechanisms regulating bone metastasis and invasion via the interaction between tumor and bone microenvironment.Principal Investigator
- Principal Investigator
  
  WATANABE Takuya
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Hokkaido University

All 2010 2009

All Journal Article Presentation

[Journal Article] Crk adaptor protein induced-phosphorylation of Gab1 on tyrosine 307 via Src is important for organization of focal adhesions and enhanced cell migration.2009
- Author(s)
  T.Watanabe, M.Tsuda, Y.Makino, T.Konstantinou, H.Nishihara, T.Majima, A.Minami, S.Feller, S.Tanaka.
- Journal Title
  
  Cell Res. 19(5)
  
  Pages: 638-650
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791381
[Journal Article] The adaptor protein Crk induces Src-dependent activation of p38 MAPK in regulation of synovial sarcoma cell proliferation.2009
- Author(s)
  T.Watanabe, M.Tsuda, S.Tanaka, Y.Ohba, H.Kawaguchi, T.Majima, H.Sawa, A.Minami.
- Journal Title
  
  Mol.Cancer Res. 7(9)
  
  Pages: 1582-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791381
[Journal Article] Crk adaptor protein induced-phosphorylation of Gab1 on tyrosine 307 via Src is important for organization of focal adhesions and enhanced cell migration2009
- Author(s)
  Watanabe T, Tsuda M, Makino Y, Konstantinou T, Nishihara H, Majima T, Minami A, Feller SM, Tanaka S.
- Journal Title
  
  Cell Res. 19
  
  Pages: 638-650
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791381
[Journal Article] The adaptor protein Crk induces Src-dependent activation of p38 MAPK in regulation of synovial sarcoma cell proliferation2009
- Author(s)
  Watanabe T, Tsuda M, Tanaka S, Ohba Y, Kawaguchi H, Majima T, Sawa H, Minami A.
- Journal Title
  
  Mol.Cancer Res. 7
  
  Pages: 1582-1592
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791381
[Presentation] Metal on metal THA後にALVALを生じた1例2010
- Author(s)
  清水智弘, 井上正弘, 沢口直弘, 渡部琢哉, 笠原靖彦, 小野寺智洋, 高橋大介, 三浪明男
- Organizer
  第118回北海道整形災害外科学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-21791381
[Presentation] 踵骨に発生したosteoid osteomaの1例2010
- Author(s)
  中野宏昭, 渡部琢哉, 沢口直弘, 三浪明男, 眞島任史, 武田直樹
- Organizer
  第118回北海道整形災害外科学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-21791381
[Presentation] 踵骨に発生した osteoid osteoma の1例2010
- Author(s)
  中野宏昭, 渡部琢哉, 沢口直弘, 三浪明男, 眞島任史, 武田直樹
- Organizer
  第118回北海道整形災害外科学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-21791381
[Presentation] Srcファミリーキナーゼ阻害剤はin vivo滑膜肉腫の増殖・浸潤・血管新生を抑制する2010
- Author(s)
  新井隆太、渡部琢哉、津田真寿美、川口秀明、大場雄介、三浪明男
- Organizer
  第25回日本整形外科学会基礎学術集会
- Place of Presentation
  京都国際会館
- Year and Date
  2010-10-15
- Data Source
  KAKENHI-PROJECT-21791381
[Presentation] Srcファミリーキナーゼ阻害薬はin vivo滑膜肉腫の増殖・浸潤・血管新生を抑制する2010
- Author(s)
  R.Arai, T.Watanabe, M.Tsuda, H.Kawaguchi, Y.Ohba, A.Minami
- Organizer
  第25回日本整形外科学会基礎学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21791381
[Presentation] Crkが制御するSrcを介した Gab1 Y307のリン酸化は、細胞接着斑の形成と運動能の充進に重要である2009
- Author(s)
  津田真寿美、渡部琢哉、牧野吉倫、川口秀明、田中伸哉、大場雄介
- Organizer
  第61回日本細胞生物学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21791381
[Presentation] Crk adaptor protein induced-phosphorylation of Gab1 on tyrosine 307 via Src is important for organization of focal adhesions and enhanced cell migration.2009
- Author(s)
  M.Tsuda, T.Watanabe, Y.Makino, H.Kawaguchi, S.Tanaka, Y.Ohba
- Organizer
  第61回日本細胞生物学会大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21791381
[Presentation] Effect of Src family kinase inhibitor on proliferation and invasion in human synovial sarcoma in vivo.2009
- Author(s)
  R.Arai, M.Tsuda, T.Watanabe, H.Kawaguchi, A.Minami, Y.Ohba
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21791381
[Presentation] Effect of Src family kinase inhibitor on proliferation and invasion in human synovial sarcoma in vivo2009
- Author(s)
  Arai R, Tsuda M, Watanabe T, Kawaguchi H, Minami A, Ohba Y
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21791381
[Presentation] 骨転移に対する放射線治療とゾレドロン酸の併用効果について2009
- Author(s)
  武田直樹, 渡部琢哉, 三浪明男, 篠原信雄, 佐澤陽
- Organizer
  第42回日本整形外科学会骨・軟部腫瘍学術集会
- Data Source
  KAKENHI-PROJECT-21791381

WATANABE Takuya 渡部 琢哉

Research Projects

Research Products

Elucidation of the mechanisms regulating bone metastasis and invasion via the interaction between tumor and bone microenvironment.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Crk adaptor protein induced-phosphorylation of Gab1 on tyrosine 307 via Src is important for organization of focal adhesions and enhanced cell migration.2009

Author(s)

Journal Title

Data Source

[Journal Article] The adaptor protein Crk induces Src-dependent activation of p38 MAPK in regulation of synovial sarcoma cell proliferation.2009

Author(s)

Journal Title

Data Source

[Journal Article] Crk adaptor protein induced-phosphorylation of Gab1 on tyrosine 307 via Src is important for organization of focal adhesions and enhanced cell migration2009

Author(s)

Journal Title

Data Source

[Journal Article] The adaptor protein Crk induces Src-dependent activation of p38 MAPK in regulation of synovial sarcoma cell proliferation2009

Author(s)

Journal Title

Data Source

[Presentation] Metal on metal THA後にALVALを生じた1例2010

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 踵骨に発生したosteoid osteomaの1例2010

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 踵骨に発生した osteoid osteoma の1例2010

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Srcファミリーキナーゼ阻害剤はin vivo滑膜肉腫の増殖・浸潤・血管新生を抑制する2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Srcファミリーキナーゼ阻害薬はin vivo滑膜肉腫の増殖・浸潤・血管新生を抑制する2010

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Crkが制御するSrcを介した Gab1 Y307のリン酸化は、細胞接着斑の形成と運動能の充進に重要である2009

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Crk adaptor protein induced-phosphorylation of Gab1 on tyrosine 307 via Src is important for organization of focal adhesions and enhanced cell migration.2009

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Effect of Src family kinase inhibitor on proliferation and invasion in human synovial sarcoma in vivo.2009

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Effect of Src family kinase inhibitor on proliferation and invasion in human synovial sarcoma in vivo2009

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 骨転移に対する放射線治療とゾレドロン酸の併用効果について2009

Author(s)

Organizer

Data Source

WATANABE Takuya 渡部琢哉