Matsumura Takuhiro 松村拓大

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MATSUMURA Takuhiro 松村拓大

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Researcher Number	00456930
Other IDs	https://orcid.org/0000-0002-3747-829X
Affiliation (Current)	2025: 金沢大学, 医学系, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2025: 金沢大学, 医学系, 准教授 2016 – 2022: 金沢大学, 医学系, 講師 2008 – 2009: Osaka University, 微生物病研究所, 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 49050:Bacteriology-related / Bacteriology (including mycology) / Bacteriology (including Mycology) Except Principal Investigator Basic Section 49050:Bacteriology-related
Keywords	Principal Investigator 神経毒素 / ボツリヌス / ボツリヌス菌 / ボツリヌス症 / 細菌毒素 / HA / M細胞 / 腸管吸収 / 神経毒素複合体 / ボツリヌス毒素 … More / 乳児ボツリヌス症 / ウマ抗毒素製剤 / 治療抗体 / 抗体カクテル / 治療効果 / ヒト型モノクローナル抗体 / ボツリヌス神経毒素 / 抗毒素製剤 / 中和抗体 / ヒト型抗体 / ワクチン / 毒素 / ボツリヌス神経毒素複合体 / 経粘膜ワクチン / 糖鎖 / 無毒成分 / ムチン / 食中毒 / 樹状細胞 / 免疫細胞 / 細胞接着 / tight junction / transcytosis / 腸管上皮バリア / Hemagglutinin / 腸管上皮細胞間バリア / 細菌 … More Except Principal Investigator ボツリヌス菌 / 感染防御 / 感染実験 / 芽胞 / 腸内細菌 / Clostridium botulinum / 感染毒素型 / ボツリヌス症 / Clostridia / クロストリジウム属 / C. botulinum / 細菌毒素 / Clostridium / ボツリヌス / 病原性 / botulinum / hemagglutinin / botulinum neurotoxin Less

ボツリヌス菌が産生する毒素関連機能未知タンパク質群の解析Principal Investigator
- Principal Investigator
  
  松村拓大
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Kanazawa University
共生細菌による病原性クロストリジウム属菌の腸管感染制御とその機構の解明
- Principal Investigator
  
  藤永由佳子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Kanazawa University
In vivo analysis of gut microbiota which prevents the intestinal botulism
- Principal Investigator
  
  Fujinaga Yukako
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Kanazawa University
Basic study for the development of human monoclonal antibodies treating botulismPrincipal Investigator
- Principal Investigator
  
  Matsumura Takuhiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Kanazawa University
Investigation of genes of unknouwn function exist in the toxin gene related region of C. botulinum
- Principal Investigator
  
  Fujinaga Yukako
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Kanazawa University
Development of mucosal vaccine using the invasion mechanism of botulinum toxinPrincipal Investigator
- Principal Investigator
  
  Matsumura Takuhiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Kanazawa University
Analysis of the interaction of botulinum neurotoxin complex with intestinal immune cellsPrincipal Investigator
- Principal Investigator
  
  Matsumura Takuhiro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Kanazawa University
Analysis of intestinal barrier disruption by HA proteins of botulinum toxinPrincipal Investigator
- Principal Investigator
  
  MATSUMURA Takuhiro
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Osaka University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2010 2009 2008

All Journal Article Presentation

[Journal Article] Botulinum neurotoxin X lacks potency in mice and in human neurons2024
- Author(s)
  Gregg BM, Matsumura T, Wentz TG, Tepp WH, Bradshaw M, Stenmark P, Johnson EA, Fujinaga Y, Pellett S.
- Journal Title
  
  mBio
  
  Volume: 15 Issue: 3
- DOI
  10.1128/mbio.03106-23
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07021
[Journal Article] Adult-onset botulism in a Japanese woman with prolonged spore excretion2023
- Author(s)
  Kihara K, Kajiyama Y, Kimura Y, Okazaki S, Esa N, Nobe R, Shimizu K, Ohno K, Motooka D, Matsumura T, Shimazu T, Nakamura S, Fujinaga Y, Mochizuki H.
- Journal Title
  
  J Infect Chemother
  
  Volume: 29 Issue: 12 Pages: 1172-1176
- DOI
  10.1016/j.jiac.2023.08.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07021
[Journal Article] Molecular engineering of a minimal E-cadherin inhibitor protein derived from Clostridium botulinum hemagglutinin2023
- Author(s)
  Amatsu Sho、Matsumura Takuhiro、Zuka Masahiko、Fujinaga Yukako
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 299 Issue: 3 Pages: 102944-102944
- DOI
  10.1016/j.jbc.2023.102944
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16240, KAKENHI-PROJECT-21K07021
[Journal Article] Rare toxin A-negative and toxin B-positive strain of Clostridioides difficile from Japan lacking a complete tcdA gene.2022
- Author(s)
  Takemori-Sakai Y, Satou K, Senda Y, Nakamura Y, Otani H, Maekawa A, Oe H, Oshima M, Yoneda-Nakagawa S, Miyagawa T, Sato K, Ogura H, Mori M, Wada T, Sakai Y, Yutani M, Matsumura T, Fujinaga Y, Gabata T, Wada T, Iwata Y.
- Journal Title
  
  J Infect Chemother.
  
  Volume: 28 Issue: 5 Pages: 651-656
- DOI
  10.1016/j.jiac.2022.01.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06394, KAKENHI-PROJECT-21K07021, KAKENHI-PROJECT-21K08224
[Journal Article] Effects of antibiotics on the viability of and toxin production by Clostridium botulinum.2021
- Author(s)
  Yutani M., Matsumura T., Fujinaga Y.
- Journal Title
  
  Microbiol Immunol.
  
  Volume: 65 Issue: 10 Pages: 432-437
- DOI
  10.1111/1348-0421.12928
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07021
[Journal Article] Functional Analysis of Botulinum Hemagglutinin (HA).2020
- Author(s)
  Matsumura T, Fujinaga Y.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 132 Pages: 191-200
- DOI
  10.1007/978-1-0716-0430-4_20
- ISBN
  9781071604298, 9781071604304
- Data Source
  KAKENHI-PROJECT-18K07107
[Journal Article] Fully Human Monoclonal Antibodies Effectively Neutralizing Botulinum Neurotoxin Serotype B2020
- Author(s)
  Matsumura Takuhiro、Amatsu Sho、Misaki Ryo、Yutani Masahiro、Du Anariwa、Kohda Tomoko、Fujiyama Kazuhito、Ikuta Kazuyoshi、Fujinaga Yukako
- Journal Title
  
  Toxins
  
  Volume: 12 Issue: 5 Pages: 302-302
- DOI
  10.3390/toxins12050302
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16240, KAKENHI-PROJECT-18K07107
[Journal Article] Collagen adhesion gene is associated with bloodstream infections caused by methicillin-resistant Staphylococcus aureus.2020
- Author(s)
  Iwata Y, Satou K, Furuichi K, Yoneda I, Matsumura T, et al.
- Journal Title
  
  Int J Infect Dis.
  
  Volume: 91 Pages: 22-31
- DOI
  10.1016/j.ijid.2019.11.003
- NAID
  120006842044
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07107, KAKENHI-PROJECT-18K08426, KAKENHI-PLANNED-17H06394, KAKENHI-PLANNED-17H06399, KAKENHI-PROJECT-17K09691, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06392
[Journal Article] Mechanism of intestinal absorption of botulinum neurotoxin complex2019
- Author(s)
  Matsumura T.
- Journal Title
  
  Nippon Saikingaku Zasshi
  
  Volume: 74 Issue: 3 Pages: 167-175
- DOI
  10.3412/jsb.74.167
- NAID
  130007753113
- ISSN
  0021-4930, 1882-4110
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-18K07107
[Journal Article] Multivalency effects of hemagglutinin component of type B botulinum neurotoxin complex on epithelial barrier disruption2018
- Author(s)
  Amatsu Sho、Matsumura Takuhiro、Yutani Masahiro、Fujinaga Yukako
- Journal Title
  
  Microbiology and Immunology
  
  Volume: 62 Issue: 2 Pages: 80-89
- DOI
  10.1111/1348-0421.12565
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15J03770, KAKENHI-PROJECT-16K19123
[Journal Article] Botulinum HA disrupts the intercellular epithelial barrier by directly binding E-cadherin2010
- Author(s)
  Sugawara Y, Matsumura T, Takegahara Y, Jin Y, Tsukasaki Y, Takeichi M, Fujinaga Y
- Journal Title
  
  J Cell Biol 189巻
  
  Pages: 691-700
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790336
[Journal Article] A novel function of botulinum toxin-associated proteins : HA proteins disrupt intestinal epithelial barrier to increase toxin absorption.2009
- Author(s)
  Fujinaga Y., Matsumura T., Jin Y., Takegahara Y., Sugawara Y.
- Journal Title
  
  Toxicon 54
  
  Pages: 583-586
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790336
[Journal Article] Disruption of the epithelial barrier by botulinum haemagglutinin (HA) Proteins-differences in cell tropism and the mechanism of action between HA proteins of types A or B, and HA proteins of type C2009
- Author(s)
  Jin Y, Takegahara Y, Sugawara Y, Matsumura T, Fujinaga Y.
- Journal Title
  
  Microbiology 155
  
  Pages: 35-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790336
[Journal Article] A novel function of botulinum toxinassociated proteins: HA proteins disrupt intestinal epithelial barrier to increase toxin absorption2009
- Author(s)
  Fujinaga Y, Matsumura T, Jin Y, Takegahara Y, Sugawara Y
- Journal Title
  
  Toxicon 54巻
  
  Pages: 583-586
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790336
[Journal Article] Disruption of the epithelial barrier by botulinum haemagglutinin (HA) proteins differences in cell tropism and the mechanism of action between HA proteins of types A or B, and HA proteins of type C2009
- Author(s)
  Jin Y, Takegahara Y, Sugawara Y, Matsumura T, Fujinaga Y
- Journal Title
  
  Microbiology 155巻
  
  Pages: 35-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790336
[Presentation] Endogenous production and neurotoxicity of novel botulinum neurotoxin (BoNT/X) in a clinical isolate2023
- Author(s)
  松村拓大、阿松翔、小林伸英、藤永由佳子
- Organizer
  第96回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-21K07021
[Presentation] A 型ボツリヌス神経毒素に対するヒト型モノクローナル抗体の開発・解析2023
- Author(s)
  山口アキ、松村拓大、小林伸英、阿松翔、藤永由佳子
- Organizer
  第96回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-21K07021
[Presentation] 抗A型ボツリヌス神経毒素ヒト型モノクローナル抗体の解析2023
- Author(s)
  山口アキ、松村拓大、小林伸英、阿松翔、藤永由佳子
- Organizer
  第69回トキシンシンポジウム
- Data Source
  KAKENHI-PROJECT-21K07021
[Presentation] ボツリヌス菌および関連するクロストリジウム属細菌が産生するメンブレンベシクルに対する炎症応答の解析2022
- Author(s)
  小林伸英、安部公博、赤木佐千代、阿松翔、松村拓大、野村暢彦、尾花望、藤永由佳子
- Organizer
  第95回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-21K07021
[Presentation] ボツリヌス菌のin vivo局在解析に向けた遺伝子改変技術の確立2022
- Author(s)
  齋藤和輝、阿松翔、松村拓大、油谷雅広、藤永由佳子
- Organizer
  第95回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-21K07021
[Presentation] A 型ボツリヌス神経毒素に対する治療用ヒト型モノクローナル抗体の開発2022
- Author(s)
  山口アキ、松村拓大、藤永由佳子
- Organizer
  第59回日本細菌学会中部支部総会
- Data Source
  KAKENHI-PROJECT-21K07021
[Presentation] ボツリヌス毒素複合体と腸管ムチンとの相互作用解析2022
- Author(s)
  阿松翔、松村拓大、森本ちよの、北村真悠、藤永由佳子
- Organizer
  第95回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-21K07021
[Presentation] Clostridium botulinumが引き起こすボツリヌス症の発症機序解明および治療法開発に向けた解析2021
- Author(s)
  松村拓大
- Organizer
  第 70 回日本感染症学会東日本地方学術集会、第 68 回日本化学療法学会東日本支部総会　合同大会
- Data Source
  KAKENHI-PROJECT-21K07021
[Presentation] ボツリヌス菌が産生するメンブレンベシクルに対する宿主応答の解析.2021
- Author(s)
  小林伸英、北村真悠、齋藤和輝、油谷雅広、阿松翔、松村拓大、藤永由佳子
- Organizer
  第94回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-18K07107
[Presentation] 組み換えボツリヌス毒素複合体の作製と腸管吸収におけるHAの機能解析.2021
- Author(s)
  森本ちよの、阿松翔、北村真悠、松村拓大、藤永由佳子
- Organizer
  第94回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-18K07107
[Presentation] B型ボツリヌス毒素を中和するヒト型モノクローナル抗体の作用機序の解明.2021
- Author(s)
  北村真悠、松村拓大、阿松翔、油谷雅広、小林伸英、藤永由佳子
- Organizer
  第94回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-18K07107
[Presentation] 乳児ボツリヌス症と乳児突然死症候群 (SIDS)との関連性.2020
- Author(s)
  松村拓大
- Organizer
  第 90 回日本感染症学会西日本地方学術集会、第 63 回日本感染症学会中日本地方学術集会、第 68 回日本化学療法学会西日本支部総会　合同大会
- Data Source
  KAKENHI-PROJECT-18K07107
[Presentation] ボツリヌス菌が産生するメンブレンベシクルによる宿主調節機構の解析.2020
- Author(s)
  小林伸英、松村拓大、油谷雅広、阿松翔、藤永由佳子
- Organizer
  第34回日本バイオフィルム学会、第57回日本細菌学会中部支部総会　合同大会
- Data Source
  KAKENHI-PROJECT-18K07107
[Presentation] 乳児ボツリヌス症と乳児突然死症候群（SIDS）との関連性2019
- Author(s)
  松村拓大, 阿松翔, 油谷雅広, 藤永由佳子
- Organizer
  第93回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-18K07107
[Presentation] E-cadherin機能阻害活性を維持した最小化ボツリヌス菌由来ヘマグルチニンの開発2019
- Author(s)
  阿松翔, 松村拓大, 油谷雅広, 藤永由佳子
- Organizer
  第92回細菌学会総会
- Data Source
  KAKENHI-PROJECT-18K07107
[Presentation] ボツリヌス菌が産生する膜小胞と宿主の相互作用の解析2019
- Author(s)
  小林伸英,松村拓大,油谷雅広,阿松翔,藤永由佳子
- Organizer
  第93回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-18K07107
[Presentation] HUMAN DERIVED MONOCLONAL ANTIBODIES EFFECTIVELY NEUTRALIZING BOTULINUM NEUROTOXIN2019
- Author(s)
  Takuhiro Matsumura, Sho Amatsu, Masahiro Yutani, Yukako Fujinaga
- Organizer
  TOXINS 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07107
[Presentation] B型ボツリヌス毒素複合体を構成するHA成分の多価性が上皮細胞間バリア破壊活性に与える影響2018
- Author(s)
  阿松翔, 松村拓大, 油谷雅広, 藤永由佳子
- Organizer
  第55回日本細菌学会中部支部総会
- Data Source
  KAKENHI-PROJECT-18K07107
[Presentation] Therapeutic and preventive effect of fully human monoclonal antibodies against type B botulinum intoxication2018
- Author(s)
  Matsumura T, Amatsu S, Yutani M, Sugawara Y, Kohda T, Misaki R, Fujiyama K, Ikuta K, Fujinaga Y
- Organizer
  Interagency Botulism Research Coordinating Committee (IBRCC)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07107
[Presentation] E-cadherin機能阻害活性を維持した最小化ボツリヌス菌ヘマグルチニン由来物質の開発2018
- Author(s)
  阿松翔, 松村拓大, 油谷雅広, 藤永由佳子
- Organizer
  第65回トキシンシンポジウム
- Data Source
  KAKENHI-PROJECT-18K07107
[Presentation] Intestinal absorption mechanism of type B1 botulinum progenitor toxin produced by strain Okra.2017
- Author(s)
  Takuhiro Matsumura, Sho Amatsu, Yo Sugawara, Masahiro Yutani, and Yukako Fujinaga
- Organizer
  Interagency Botulism Research Coordinating Committee (IBRCC)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19123
[Presentation] 血清型A型およびB型ボツリヌス毒素の腸管吸収機構2017
- Author(s)
  松村拓大
- Organizer
  第90回日本細菌学会総会
- Place of Presentation
  仙台
- Year and Date
  2017-03-19
- Data Source
  KAKENHI-PROJECT-16K19123
[Presentation] 血清型A型ボツリヌス神経毒素複合体の宿主体内侵入機構2016
- Author(s)
  松村拓大
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K19123
[Presentation] Reconstitution and dissection of epithelial barrier-disrupting activity of type B botulinum HA2010
- Author(s)
  竹ヶ原夕紀、菅原庸、松村拓大、藤永由佳子
- Organizer
  第83回日本細菌学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20790336
[Presentation] The botulinum toxin crosses the intestinal epithelial barrier via M cell2009
- Author(s)
  Matsumura T, Jin Y, Takegahara Y, Sugawara Y, Fujinaga Y
- Organizer
  第82回日本細菌学会総会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-20790336
[Presentation] The botulinum toxin crosses the intestinal epithelial barrier viaM cell2009
- Author(s)
  松村拓大
- Organizer
  第82回日本細菌学会総会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-20790336
[Presentation] Mechanism for Epithelial Barrier Disruption by Botulinum HA2009
- Author(s)
  Takegahara, Y., Matsumura, T., Sugawara, Y., Fui inaga, Y.
- Organizer
  Etox 14 (European Workshop on Bacterial Protein Toxins)
- Place of Presentation
  Obernai, France
- Data Source
  KAKENHI-PROJECT-20790336
[Presentation] 上皮細胞バリア破壊因子botulinum HAのサブユニット機能解析2009
- Author(s)
  竹ヶ原夕紀、菅原庸、松村拓大、藤永由佳子
- Organizer
  第82回日本生化学大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20790336
[Presentation] ボツリヌ畑は上皮細胞バア破壊因子である2009
- Author(s)
  竹ヶ原夕紀、菅原庸、松村拓大、藤永由佳子
- Organizer
  第62回日本細菌学会関西支部会
- Place of Presentation
  大阪
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-20790336
[Presentation] Analysis of intestinal absorption of botulinum toxin2008
- Author(s)
  松村拓大
- Organizer
  FORUM OF THE NETWORK OF RESEARCH CENTERS ON INFECTIOUS DISEASES
- Place of Presentation
  National Institute of Hygiene and Epidemiology (NIHE), Hanoi-Vietnam
- Year and Date
  2008-10-06
- Data Source
  KAKENHI-PROJECT-20790336
[Presentation] Analysis of intestinal absorption of botulinum toxin2008
- Author(s)
  Matsumura T, Jin Y, Takegahara Y, Sugawara Y, Fujinaga Y
- Organizer
  FORUM OF THE NETWORK OF RESEARCH CENTERS ON INFECTIOUS DISEASES
- Place of Presentation
  National Institute of Hygiene and Epidemiology(NIHE), Hanoi- Vietnam
- Year and Date
  2008-10-06
- Data Source
  KAKENHI-PROJECT-20790336

1. Fujinaga Yukako (60252954)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. 小林伸英 (30712799)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 油谷雅広 (20648810)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 阿松翔

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Matsumura Takuhiro 松村 拓大

MATSUMURA Takuhiro 松村 拓大

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Co-Researchers

ボツリヌス菌が産生する毒素関連機能未知タンパク質群の解析Principal Investigator

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共生細菌による病原性クロストリジウム属菌の腸管感染制御とその機構の解明

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In vivo analysis of gut microbiota which prevents the intestinal botulism

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Basic study for the development of human monoclonal antibodies treating botulismPrincipal Investigator

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Investigation of genes of unknouwn function exist in the toxin gene related region of C. botulinum

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Development of mucosal vaccine using the invasion mechanism of botulinum toxinPrincipal Investigator

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Analysis of the interaction of botulinum neurotoxin complex with intestinal immune cellsPrincipal Investigator

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Analysis of intestinal barrier disruption by HA proteins of botulinum toxinPrincipal Investigator

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[Journal Article] Botulinum neurotoxin X lacks potency in mice and in human neurons2024

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[Journal Article] Adult-onset botulism in a Japanese woman with prolonged spore excretion2023

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[Journal Article] Molecular engineering of a minimal E-cadherin inhibitor protein derived from Clostridium botulinum hemagglutinin2023

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[Journal Article] Rare toxin A-negative and toxin B-positive strain of Clostridioides difficile from Japan lacking a complete tcdA gene.2022

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[Journal Article] Effects of antibiotics on the viability of and toxin production by Clostridium botulinum.2021

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[Journal Article] Functional Analysis of Botulinum Hemagglutinin (HA).2020

Author(s)

Matsumura Takuhiro 松村拓大

MATSUMURA Takuhiro 松村拓大