YOSHIMOTO Seichi 吉本世一

… Alternative Names

吉本世一ヨシモトセイイチ

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Researcher Number	00462242
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立がん研究センター, 中央病院, 科長
Affiliation (based on the past Project Information) *help	2015 – 2023: 国立研究開発法人国立がん研究センター, 中央病院, 科長 2015: 国立研究開発法人国立がん研究センター, その他部局等, その他
Review Section/Research Field	Except Principal Investigator Surgical dentistry / Medium-sized Section 57:Oral science and related fields / Basic Section 57060:Surgical dentistry-related / Basic Section 56050:Otorhinolaryngology-related
Keywords	Except Principal Investigator 口腔がん / 末梢循環腫瘍細胞 / ゲノム解析 / 歯学 / 外科 / 癌 / 一細胞酵素活性 / 一分子酵素活性 / 1細胞酵素活性 / 免疫チェックポイント阻害 … More / cell free DNA / CTCs / 細胞フリーDNA / 抹消循環腫瘍ＤＮＡ（ctDNA) / 抹消循環腫瘍細胞（ＣＴＣｓ） / 免疫チェックポイント阻害薬 / 免疫チェックポイント / リキッドバイオプシー / 口腔がんバイオマーカー / ctDNA / CTCｓ / 末梢循環腫瘍細胞（CTCｓ） / 末梢循環DNA（ctDNA) / 免疫チェックポイント療法 / 次世代シーケンス / 末梢循環腫瘍DNA / リキッドバイオプシー解析 / 免疫チェックポイント治療 / サブクローン進化 / ゲノム / ゲノム進化 / 頭頸部扁平上皮癌 / TP53 / 腫瘍内不均一性 / 頭頸部癌 / 転移活性化予測バイオマーカー / 後発頸部リンパ節転移 / I/II期舌がん / チロシンキナーゼ / 抗体基盤プロテオミクス / Ⅰ/Ⅱ期舌がん / 治療標的探索 / FISH / 治療戦略決定バイオマーカー / 転移活性 / 補助化学療法 / 舌がん / 予後マーカー / 遺伝子増幅 / ACTN4 / バイオマーカー / 末梢腫瘍循環細胞 / オミクス解析 / 1細胞解析 Less

Development of a method for the analysis of single-cell and single-molecule enzyme activities from oral cancer liquid biopsy.
- Principal Investigator
  
  Honda Kazufumi
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Nippon Medical School
Intratumor heterogeneity in head and neck cancer by genomic, epigenomic, and transcriptomic analysis.
- Principal Investigator
  
  Kobayashi Kenya
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  The University of Tokyo
  National Cancer Center Japan
Establishment of a method for predicting the efficacy of immune checkpoint inhibitors in oral cancer by liquid biopsy.
- Principal Investigator
  
  Honda Kazufumi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nippon Medical School
  National Cancer Center Japan
Omic analysis from single cell circulating tumor cells of oral cancer
- Principal Investigator
  
  Kazufumi Honda
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  National Cancer Center Japan
Discovery of the novel targets for tongue cancer
- Principal Investigator
  
  Kazufumi Honda
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  National Cancer Center Japan
Establishment of practical methods for next generation sequence from circulating tumor cells and circulating cell free DNA of oral cancer
- Principal Investigator
  
  Honda Kazufumi
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  National Cancer Center Japan

All 2021 2020 2019 2017 2016 2015

All Journal Article Presentation

[Journal Article] BP180 Is a Prognostic Factor in Head and Neck Squamous Cell Carcinoma2021
- Author(s)
  MENG XUE、MATSUMOTO FUMIHIKO、MORI TAISUKE、MIURA NAMI、INO YOSHINORI、ONIDANI KAORU、KOBAYASHI KENYA、MATSUZAKI YUSUKE、YOSHIMOTO SEIICHI、IKEDA KATSUHISA、HONDA KAZUFUMI
- Journal Title
  
  Anticancer Research
  
  Volume: 41 Issue: 2 Pages: 1089-1099
- DOI
  10.21873/anticanres.14867
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07383, KAKENHI-PROJECT-19H03856
[Journal Article] Uniform infection screening allowed safe head and neck surgery during the coronavirus disease 2019 pandemic in Japan2021
- Author(s)
  Akiko I, Kobayashi K, Shiotsuka M, Sato T, Omura G, Matsumoto Y, Ikeda A, Sakai A, Eguchi K, Takano T, Matsumot F, Kobayashi O, Iwata S, Yoshimoto S.
- Journal Title
  
  Jpn J Clin Oncol .
  
  Volume: 51 Issue: 3 Pages: 400-407
- DOI
  10.1093/jjco/hyaa195
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09923, KAKENHI-PROJECT-18K09339
[Journal Article] Olfactory preservation in craniofacial resection of tumor invading hemianterior skull base: operative video.2021
- Author(s)
  Kobayashi K, Miyakita Y, Matsumoto F, Omura G, Matsumura S, Ikeda A, Eguchi K, Ito A, Narita Y, Akazawa S, Yoshimoto S.
- Journal Title
  
  J Neurol Surg B.
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09923
[Journal Article] Carotid artery ligation via sternotomy as a palliative surgery: Case report of advanced inttramediastinal malignant soft tissue tumor.2021
- Author(s)
  Eguchi K, Kobayashi K, Takano T, Ito A, Sakai A, Ikeda A, Matsumoto Y, Omura G, Matsumoto F, Yoshimoto S.
- Journal Title
  
  Clin Case Rep.
  
  Volume: 9 Pages: 10-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09923
[Journal Article] Full-coverage TP53 deep sequencing of recurrent head and neck squamous cell carcinoma facilitates prognostic assessment after recurrence.2021
- Author(s)
  Kobayashi K, Yoshimoto S, Ando M, Matsumoto F, Murakami N, Omura G, Honma Y, Matsumoto Y, Ikeda A, Sakai A, Eguchi K, Ito A, Ryo E, Yatabe Y, Mori T.
- Journal Title
  
  Oral Oncol.
  
  Volume: 113 Pages: 105091-105091
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09923
[Journal Article] Uniform infection screening allowed safe head and neck surgery during the coronavirus disease 2019 pandemic in Japan.2021
- Author(s)
  Ito A, Kobayashi K, Shiotsuka M, Sato T, Omura G, Matsumoto Y, Ikeda A, Sakai A, Eguchi K, Takano T, Matsumoto F, Kobayashi O, Iwata S, Yoshimoto S.
- Journal Title
  
  Jpn J Clin Oncol.
  
  Volume: 51 Pages: 400-407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09923
[Journal Article] ossible Therapeutic Strategy Involving the Purine Synthesis Pathway Regulated by ITK in Tongue Squamous Cell Carcinoma.2021
- Author(s)
  Onidani K, Miura N, Sugiura Y, Abe Y, Watabe Y, Kakuya T, Mori T, Yoshimoto S, Adachi J, Kiyoi T, Kabe Y, Suematsu M, Tomonaga T, Shibahara T, Honda K.
- Journal Title
  
  Cancers
  
  Volume: 13 Issue: 13 Pages: 3333-3333
- DOI
  10.3390/cancers13133333
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03749, KAKENHI-PROJECT-20K07333, KAKENHI-PROJECT-20K07383, KAKENHI-PROJECT-21K06845, KAKENHI-PROJECT-23K20389, KAKENHI-PROJECT-19H03856
[Journal Article] Risk Factors for Delayed Surgical Recovery and Massive Bleeding in Skull Base Surgery.2020
- Author(s)
  Kobayashi K, Matsumoto F, Miyakita Y, Arikawa M, Omura G, Matsumura S, Ikeda A, Sakai A, Eguchi K, Narita Y, Akazawa S, Miyamoto S, Yoshimoto S.
- Journal Title
  
  Biomed Hub.
  
  Volume: 5 Issue: 2 Pages: 87-100
- DOI
  10.1159/000507750
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09339, KAKENHI-PROJECT-19K09923
[Journal Article] Full-coverage TP53 deep sequencing of recurrent head and neck squamous cell carcinoma facilitates prognostic assessment after recurrence.2020
- Author(s)
  Kobayashi K, Yoshimoto S, Ando M, Matsumoto F, Murakami N, Omura G, Honma Y, Matsumoto Y, Ikeda A, Sakai A, Eguchi K, Ito A, Eigitsu R, Yatabe Y, Mori T.
- Journal Title
  
  Oral oncology
  
  Volume: 113 Pages: 105091-105091
- DOI
  10.1016/j.oraloncology.2020.105091
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09923, KAKENHI-PROJECT-20K07383, KAKENHI-PROJECT-20H03461, KAKENHI-PROJECT-18K09339
[Journal Article] All-Exon TP53 Sequencing and Protein Phenotype Analysis Accurately Predict Clinical Outcome after Surgical Treatment of Head and Neck Squamous Cell Carcinoma2019
- Author(s)
  Kobayashi K, Yoshimoto S, Matsumoto F, Ando M, Murakami N, Omura G, Fukasawa M, Matsumoto Y, Matsumura M, Akamatsu M, Hiraoka N, Eigitsu R, and Mori T
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: 印刷中 Issue: 7 Pages: 2294-2303
- DOI
  10.1245/s10434-019-07287-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09339, KAKENHI-PROJECT-19K09923, KAKENHI-PROJECT-16K11246, KAKENHI-PROJECT-17K08710
[Journal Article] ASO Author Reflections: Precise p53 Analysis in Formalin-Fixed Paraffin-Embedded Specimens Can Predict Head and Neck Squamous Cell Carcinoma Outcomes2019
- Author(s)
  Mori Taisuke、Kobayashi Kenya、Yoshimoto Seiichi
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: 26 Issue: S3 Pages: 614-615
- DOI
  10.1245/s10434-019-07433-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09923, KAKENHI-PROJECT-17K08710
[Journal Article] A surgical approach to schwannomas originating from the esophageal branch of the recurrent laryngeal nerve: Pictorial essay.2019
- Author(s)
  Kobayashi K, Matsumoto Y, Matsumoto F, Sato T, Mori T, Tsuchida T, Omura G, Matsumura S, Ikeda A, Sakai A, Eguchi K, and Yoshimoto S.
- Journal Title
  
  Head Neck
  
  Volume: 41 Issue: 11 Pages: 4054-4059
- DOI
  10.1002/hed.25921
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09339, KAKENHI-PROJECT-19K09923, KAKENHI-PROJECT-16K11246
[Journal Article] Monitoring of cancer patients via next‐generation sequencing of patient‐derived circulating tumor cells and tumor DNA2019
- Author(s)
  Onidani Kaoru、Shoji Hirokazu、Kakizaki Takahiko、Yoshimoto Seiichi、Okaya Shinobu、Miura Nami、Sekikawa Shoichi、Furuta Koh、Lim Chwee Teck、Shibahara Takahiko、Boku Narikazu、Kato Ken、Honda Kazufumi
- Journal Title
  
  Cancer Science
  
  Volume: 110 Issue: 8 Pages: 2590-2599
- DOI
  10.1111/cas.14092
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07341, KAKENHI-PROJECT-19K08432, KAKENHI-PROJECT-17K11888, KAKENHI-PROJECT-19H03856
[Journal Article] Prognostic significance of gene amplification of ACTN4 in stage I and II oral tongue cancer.2017
- Author(s)
  Kakuya T, Mori T, Yoshimoto S, Watabe Y, Miura N, Shoji H, Onidani K, Shibahara T, Honda K.
- Journal Title
  
  Int J Oral Maxillofac Surg.
  
  Volume: 46（8） Issue: 8 Pages: 968-976
- DOI
  10.1016/j.ijom.2017.03.001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19381, KAKENHI-PROJECT-16H05547, KAKENHI-PROJECT-16K15833
[Journal Article] Patterns of recurrence after selective postoperative radiation therapy for patients with head and neck squamous cell carcinoma2016
- Author(s)
  Murakami N, Matsumoto F, Yoshimoto S, Ito Y, Mori T, Ueno T, Tuchida K, Kashihara T, Kobayashi K, Harada K, Kitaguchi M, Sekii S, Umezawa R, Takahashi K, Inaba K, Igaki H, Itami J
- Journal Title
  
  BMC Cancer
  
  Volume: 16 Issue: 1 Pages: 192-195
- DOI
  10.1186/s12885-016-2229-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460463, KAKENHI-PROJECT-26461873, KAKENHI-PROJECT-15K19836, KAKENHI-PROJECT-23390469, KAKENHI-PROJECT-15K15751, KAKENHI-PROJECT-16K10410
[Presentation] High-grade transformationを起こした唾液腺明細胞癌のゲノム解析2021
- Author(s)
  小林謙也、江口紘太郎、坂井梓、松本吉史、小村豪、吉本世一
- Organizer
  第31回日本頭頸部外科学会
- Data Source
  KAKENHI-PROJECT-19K09923
[Presentation] 当科における耳下腺癌治療の顔面神経処理2021
- Author(s)
  小林謙也、高野智誠、伊東明子、江口絋太郎、坂井梓、池田篤生、松本吉史、小村豪、吉本世一
- Organizer
  第45回日本頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-19K09923
[Presentation] 当院における小児悪性腫瘍の治療経験2020
- Author(s)
  小林謙也、江口紘太朗、坂井梓、池田篤生、松村聡子、小村豪、吉本世一
- Organizer
  第３０回頭頸部外科学会
- Data Source
  KAKENHI-PROJECT-19K09923
[Presentation] 頭蓋底手術における嗅神経温存の工夫2020
- Author(s)
  小林　謙也、伊東　明子、江口　紘太朗、坂井　梓、池田　篤生、松村　聡子、小村　豪、吉本　世一
- Organizer
  頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-19K09923
[Presentation] 再発頭頸部扁平上皮癌におけるTP53変異の時系列解析2019
- Author(s)
  小林謙也、森泰介昌、安藤瑞生、坂井梓、池田篤生、赤松摩紀、松村聡子、小村豪、松本文彦、吉本世一
- Organizer
  第43回頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-19K09923
[Presentation] Risk factors for delayed surgical recovery and massive bleeding in skull base surgery.2019
- Author(s)
  Kobayashi K, Matsumoto F, Miyakita Y, Moti T, Omura G, Fukasawa M, Matsumoto Y, Matsumuta S, Akamatsu M, Yoshimoto S
- Organizer
  the 6th Asian society of head and neck oncology
- Data Source
  KAKENHI-PROJECT-19K09923
[Presentation] Next-generation sequencing of circulating tumor cells isolated from peripheral blood of patients with head and neck or gastrointestinal cancer,2017
- Author(s)
  Kaoru Onidani, Seiichi Yoshimoto, Nami Miura, Hirokazu Shoji, Ken Kato, Takahiko Shibahara, Kazufumi Honda
- Organizer
  ESMO Asia2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15833
[Presentation] Next-generation sequencing of circulating tumor cells isolated from peripheral blood of patients with head and neck or gastrointestinal cancer2017
- Author(s)
  Kaoru Onidani, Seiichi Yoshimoto, Nami Miura, Hirokazu Shoji, Ken Kato, Takahiko Shibahara, Kazufumi Honda
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16K15833
[Presentation] 次世代シーケンサーによる血中循環腫瘍細胞(CTCs)の遺伝子変異プロファイリング2017
- Author(s)
  鬼谷　薫、吉本世一、三浦奈美、庄司広和、加藤　健、柴原孝彦、本田一文
- Organizer
  第37回日本分子腫瘍マーカー研究会
- Data Source
  KAKENHI-PROJECT-16K15833
[Presentation] Next-generation sequencing of circulating tumor cells isolated from peripheral blood of patients with head and neck or gastrointestinal cancer2017
- Author(s)
  Kaoru Onidani, Seiichi Yoshimoto, Nami Miura, Hirokazu Shoji, Ken Kato, Takahiko Shibahara, Kazufumi Honda
- Organizer
  ESMO Asia2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05547
[Presentation] Next generation sequencing of circulating tumor cells isolated from the peripheral blood and circulating free DNA of solid cancer patients.2015
- Author(s)
  Tomohiko Kakizaki, Hirokazu Shoji, Koh Furuta, Ken Kato, Seiichi Yoshimoto, Fumihiko Matsumoto, Taisuke Mori, Tomohiro Sakuma, Tesshi Yamada, Chwee Teck Lim and Kazufumi Honda
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  愛知県
- Year and Date
  2015-10-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15751
[Presentation] Copy number of ACTN4 is a predictive indicator for late metastasis of cervical lymph nodes in early-stage tongue cancer2015
- Author(s)
  Takanori Kakuya, Taisuke Mori, Yukio Watabe, Seichi Yoshimoto, Nami Miura, Takeshi Nomura, Tesshi Yamada, Huang Wilber, Takahiko Shibahara, Kazufumi Honda
- Organizer
  the International Conference on Oral and Maxillofacial Surgery 2015
- Place of Presentation
  オーストラリア
- Year and Date
  2015-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15751

1. Kazufumi Honda (10260936)

# of Collaborated Projects: 5 results

# of Collaborated Products: 7 results
2. MORI Taisuke (00296708)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
3. 本間義崇 (30719943)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. Kobayashi Kenya (80648311)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
5. 安藤瑞生 (60511467)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. Itami Jun

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 小村豪

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
8. 庄司広和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 三浦奈美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 朝長毅

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YOSHIMOTO Seichi 吉本 世一

吉本 世一 ヨシモト セイイチ

Research Projects

Research Products

Co-Researchers

Development of a method for the analysis of single-cell and single-molecule enzyme activities from oral cancer liquid biopsy.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Intratumor heterogeneity in head and neck cancer by genomic, epigenomic, and transcriptomic analysis.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of a method for predicting the efficacy of immune checkpoint inhibitors in oral cancer by liquid biopsy.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Omic analysis from single cell circulating tumor cells of oral cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Discovery of the novel targets for tongue cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of practical methods for next generation sequence from circulating tumor cells and circulating cell free DNA of oral cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] BP180 Is a Prognostic Factor in Head and Neck Squamous Cell Carcinoma2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Uniform infection screening allowed safe head and neck surgery during the coronavirus disease 2019 pandemic in Japan2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Olfactory preservation in craniofacial resection of tumor invading hemianterior skull base: operative video.2021

Author(s)

Journal Title

Data Source

[Journal Article] Carotid artery ligation via sternotomy as a palliative surgery: Case report of advanced inttramediastinal malignant soft tissue tumor.2021

Author(s)

Journal Title

Data Source

[Journal Article] Full-coverage TP53 deep sequencing of recurrent head and neck squamous cell carcinoma facilitates prognostic assessment after recurrence.2021

Author(s)

Journal Title

Data Source

[Journal Article] Uniform infection screening allowed safe head and neck surgery during the coronavirus disease 2019 pandemic in Japan.2021

Author(s)

Journal Title

Data Source

[Journal Article] ossible Therapeutic Strategy Involving the Purine Synthesis Pathway Regulated by ITK in Tongue Squamous Cell Carcinoma.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Risk Factors for Delayed Surgical Recovery and Massive Bleeding in Skull Base Surgery.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Full-coverage TP53 deep sequencing of recurrent head and neck squamous cell carcinoma facilitates prognostic assessment after recurrence.2020

Author(s)

Journal Title

YOSHIMOTO Seichi 吉本世一

吉本世一ヨシモトセイイチ

[Presentation] 当院における小児悪性腫瘍の治療経験2020