Iizuka Akira 飯塚明

… Alternative Names

飯塚明イイヅカアキラ

Less

Researcher Number	00463183
Affiliation (Current)	2025: 静岡県立静岡がんセンター(研究所), その他部局等, 研究員
Affiliation (based on the past Project Information) *help	2016 – 2019: 静岡県立静岡がんセンター(研究所), その他部局等, 研究員 2014 – 2015: 静岡県立静岡がんセンター(研究所), その他部局等, その他
Review Section/Research Field	Principal Investigator Tumor therapeutics
Keywords	Principal Investigator マウスモデル / 腫瘍免疫 / NOGマウス / CD3 / T細胞 / PD-L1 / ヒト化マウスモデル / 乳癌 / 二重特異性抗体 / B7-H4 / 癌精巣抗原 / 変異抗原 / グリオーマ

Bispesific-antibody targeting B7-H4Principal Investigator
- Principal Investigator
  
  Iizuka Akira
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Shizuoka Cancer Center Research Institute
Anti-tumor immunotherapy in humanized the NOG-MHC double knockout mousePrincipal Investigator
- Principal Investigator
  
  Iizuka Akira
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Shizuoka Cancer Center Research Institute

All 2019 2018 2017 2015 2014

All Journal Article Presentation Patent

[Journal Article] A T-cell-engaging B7-H4/CD3-bispecific Fab-scFv Antibody Targets Human Breast Cancer2019
- Author(s)
  Iizuka Akira、Nonomura Chizu、Ashizawa Tadashi、Kondou Ryota、Ohshima Keiichi、Sugino Takashi、Mitsuya Koichi、Hayashi Nakamasa、Nakasu Yoko、Maruyama Kouji、Yamaguchi Ken、Akiyama Yasuto
- Journal Title
  
  Clinical Cancer Research
  
  Volume: 25 Issue: 9 Pages: 2925-2934
- DOI
  10.1158/1078-0432.ccr-17-3123
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07235, KAKENHI-PROJECT-18K07315, KAKENHI-PROJECT-17K07209
[Journal Article] Antitumor Effect of Programmed Death-1 (PD-1) Blockade in Humanized the NOG-MHC Double Knockout Mouse.2017
- Author(s)
  Ashizawa T, Iizuka A, Nonomura C, Kondou R, Maeda C, Miyata H, Sugino T, Mitsuya K, Hayashi N, Nakasu Y, Maruyama K, Yamaguchi K, Katano I, Ito M, Akiyama Y.
- Journal Title
  
  Clinical Cancer Research
  
  Volume: 23(1) Issue: 1 Pages: 149-158
- DOI
  10.1158/1078-0432.ccr-16-0122
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430178, KAKENHI-PROJECT-16K08727, KAKENHI-PROJECT-16K18405
[Journal Article] Immunologically augmented skin flap as a novel dendritic cell vaccine against head and neck cancer in a rat model.2015
- Author(s)
  Inoue K, Saegusa N, Omiya M, Ashizawa T, Miyata H, Komiyama M, Iizuka A, Kume A, Sugino T, Yamaguchi K, Kiyohara Y, Nakagawa M, Akiyama Y.
- Journal Title
  
  Cancer Sci.
  
  Volume: 106 (2) Issue: 2 Pages: 143-150
- DOI
  10.1111/cas.12586
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24501318, KAKENHI-PROJECT-24592725, KAKENHI-PROJECT-25430166, KAKENHI-PROJECT-26430178
[Journal Article] Novel cancer-testis antigen expression on glioma cell lines derived from high-grade glioma patients.2014
- Author(s)
  Akiyama Y, Komiyama M, Miyata H, Yagoto M, Ashizawa T, Iizuka A, Oshita C, Kume A, Nogami M, Ito I, Watanabe R, Sugino T, Mitsuya K, Hayashi N, Nakasu Y, Yamaguchi K.
- Journal Title
  
  Oncol Rep.
  
  Volume: 31 Issue: 4 Pages: 1683-1690
- DOI
  10.3892/or.2014.3049
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24501318, KAKENHI-PROJECT-24501362, KAKENHI-PROJECT-26430178
[Patent] 国際特許、優先権2017
- Inventor(s)
  AKIYAMA Yasuto; IIZUKA Akira
- Industrial Property Rights Holder
  Shizuoka prefecture
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-17K07235
[Presentation] Anti-B7-H4 bispecific antibody targets human breast cancers2019
- Author(s)
  飯塚　明
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K07235
[Presentation] T-cell-engaging B7-H4/CD3 bispecific Fab-scFv antibody targeting human breast cancer2018
- Author(s)
  Akira Iizuka, Tadashi Ashizawa, Keiichi Ohshima, Masatoshi Kusuhara, Ken Yamaguchi, Yasuto Akiyama
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K07235
[Presentation] Anti-PD-1 antibody therapy using humanized MHC-dKO NOG mouse2015
- Author(s)
  Tadashi Ashizawa, Akira Iizuka, Kouji Maruyama, Ken Yamaguchi, Yasuto Akiyama
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  Nagoya Congress Center
- Year and Date
  2015-10-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430178

1. 秋山靖人 (70222552)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
2. 杉野隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Iizuka Akira 飯塚 明

飯塚 明 イイヅカ アキラ

Research Projects

Research Products

Co-Researchers

Bispesific-antibody targeting B7-H4Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Anti-tumor immunotherapy in humanized the NOG-MHC double knockout mousePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A T-cell-engaging B7-H4/CD3-bispecific Fab-scFv Antibody Targets Human Breast Cancer2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Antitumor Effect of Programmed Death-1 (PD-1) Blockade in Humanized the NOG-MHC Double Knockout Mouse.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Immunologically augmented skin flap as a novel dendritic cell vaccine against head and neck cancer in a rat model.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Novel cancer-testis antigen expression on glioma cell lines derived from high-grade glioma patients.2014

Author(s)

Journal Title

DOI

Data Source

[Patent] 国際特許、優先権2017

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Presentation] Anti-B7-H4 bispecific antibody targets human breast cancers2019

Author(s)

Organizer

Data Source

[Presentation] T-cell-engaging B7-H4/CD3 bispecific Fab-scFv antibody targeting human breast cancer2018

Author(s)

Organizer

Data Source

[Presentation] Anti-PD-1 antibody therapy using humanized MHC-dKO NOG mouse2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Iizuka Akira 飯塚明

飯塚明イイヅカアキラ