YOSHINO OSAMU 吉野修

… Alternative Names

YOSHINO Osamu 吉野修

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Researcher Number	00466757
Affiliation (Current)	2025: 山梨大学, 大学院総合研究部, 教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 山梨大学, 大学院総合研究部, 教授 2021 – 2023: 山梨大学, 大学院総合研究部, 准教授 2019 – 2020: 北里大学, 医学部, 准教授 2013 – 2016: 富山大学, 大学院医学薬学研究部(医学), 准教授 2013 – 2014: 富山大学, その他の研究科, 准教授 2013: 富山大学, 大学院医学薬学(医学), 准教授 2012: 東京大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology Except Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Basic Section 90120:Biomaterials-related / Biomedical engineering/Biomaterial science and engineering
Keywords	Principal Investigator 子宮内膜症 / 女性ホルモン / 腸内細菌 / M1/M2型 / 血管新生因子 / S1P / IL-33 / 血管新生 / 着床 / マクロファージ … More / 自律神経 / 炎症 / 副交感神経 / 交感神経 / ストレス / 疼痛 / ブラジキニン … More Except Principal Investigator 再生医療 / 子宮再生 / 着床不全 / ネオセルフ抗体 / 子宮内膜症 / 抗リン脂質抗体 / 自己抗体 / 不妊症 / 不育症 / 超高静水圧 / 不妊治療 / 再生子宮 / 脱細胞化担体 Less

平滑筋機能に着目した真に着床・妊娠を可能とする再生子宮
- Principal Investigator
  
  古川克子
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Tokyo Institute of Technology
  The University of Tokyo
ネオ・セルフ抗体による不妊症、子宮内膜症の病態解明と治療法の確立
- Principal Investigator
  
  山田秀人
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Kobe University
女性ホルモンによる腸内細菌を介した免疫細胞制御機構の解明Principal Investigator
- Principal Investigator
  
  吉野修
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  University of Yamanashi
Elucidation and treatment of physiological phenomena and abnormalities of pregnancy based on macrophage balancePrincipal Investigator
- Principal Investigator
  
  YOSHINO OSAMU
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  University of Yamanashi
  Kitasato University
The effect of stress on immune system and the progression of endometriosis.Principal Investigator
- Principal Investigator
  
  YOSHINO OSAMU
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  University of Toyama
Development of innovative implantation patch for medical treatments of infertility
- Principal Investigator
  
  Ushida Takashi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  The University of Tokyo
the bradykinin system in endometriosisPrincipal Investigator
- Principal Investigator
  
  YOSHINO Osamu
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  University of Toyama
  The University of Tokyo

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Book Other

[Book] HORMONE FRONTIER IN GYNECOLOGY(Vol.23 No.2)2016
- Author(s)
  古川克子,廣田泰,吉野修,岸田昌夫,牛田多加志,齋藤滋,大須賀穣.
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-25560191
[Journal Article] 着床不全とネオ・セルフ抗体2023
- Author(s)
  小野洋輔, 和田真一郎, 吉野修, 山田秀
- Journal Title
  
  日本IVF学会誌
  
  Volume: 26 Pages: 40-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K08888
[Journal Article] Anti-β2-Glycoprotein I/HLA-DR antibody in infertility.2023
- Author(s)
  Ono Y, Wada S, Ota H, Fukushi Y, Tanimura K, Yoshino O, Arase H, Yamada H.
- Journal Title
  
  J Reprod Immunol
  
  Volume: 158 Pages: 103955-103955
- DOI
  10.1016/j.jri.2023.103955
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09642, KAKENHI-PROJECT-23K08888
[Journal Article] National survey of abnormal uterine bleeding according to the FIGO classification in Japan2022
- Author(s)
  Kitahara Yoshikazu、Hiraike Osamu、Ishikawa Hiroshi、Kugu Koji、Takai Yasushi、Yoshino Osamu、Ono Masanori、Maekawa Ryo、Ota Ikuko、Iwase Akira
- Journal Title
  
  Journal of Obstetrics and Gynaecology Research
  
  Volume: 49 Issue: 1 Pages: 321-330
- DOI
  10.1111/jog.15464
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K09489, KAKENHI-PROJECT-19K09823
[Journal Article] Guidelines for Reproductive Medicine in Japan2022
- Author(s)
  Yamada Mitsutoshi、Osuka Satoko、Kanasaki Haruhiko、Kawano Yasushi、Kawamura Kazuhiro、Kishi Hiroshi、Kimura Fuminori、Kuroda Shinnosuke、Kuwahara Akira、Tamura Hiroshi、Jwa Seung Chik、Baba Tsuyoshi、Harada Miyuki、Hirata Tetsuya、Yoshino Osamu、Hirota Yasushi、Tsujimura Akira、Kuji Naoaki、Osuga Yutaka
- Journal Title
  
  Reproductive Medicine and Biology
  
  Volume: 21 Issue: 1 Pages: 1-1
- DOI
  10.1002/rmb2.12483
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09593, KAKENHI-PROJECT-21K09504, KAKENHI-PROJECT-22K09612, KAKENHI-PROJECT-21K18298, KAKENHI-PROJECT-22K19595, KAKENHI-PROJECT-19H01067, KAKENHI-PROJECT-20H03826, KAKENHI-PROJECT-16K11078, KAKENHI-PROJECT-19K09823, KAKENHI-PROJECT-20K18217, KAKENHI-PROJECT-22K19596, KAKENHI-PROJECT-23K23803
[Journal Article] Oral Gonadotropin-Releasing Hormone Antagonist Relugolix Has the Same Effect as Gonadotropin-Releasing Hormone Agonist Injections in Terms of Preparation for Transcervical Resection Myomectomy2022
- Author(s)
  Yoshino Osamu、Ito Mika、Hiraoka Takehiro、Ono Yosuke、Tanaka Kouta、Iwahata Shunsuke、Honda Masako、Furue Akiko、Nishijima Junichi、Shimoda Takahito、Iwase Haruko、Miki Akinori、Tagaya Hikaru、Hirata Shuji、Unno Nobuya
- Journal Title
  
  Gynecology and Minimally Invasive Therapy
  
  Volume: 11 Issue: 4 Pages: 238-238
- DOI
  10.4103/gmit.gmit_9_22
- Data Source
  KAKENHI-PROJECT-19K09823
[Journal Article] Guideline for Gynecological Practice in Japan: Japan Society of Obstetrics and Gynecology and Japan Association of Obstetricians and Gynecologists 2020 edition2021
- Author(s)
  Kawaguchi R, Matsumoto K, Ishikawa T, Ishitani K, Okagaki R, Ogawa M, Oki T, Ozawa N, Kawasaki K, Kuwabara Y, Koga K, Sato Y, Takai Y, Tanaka K, Tanebe K, Terauchi M, Todo Y, Nose-Ogura S, Noda T, Baba T, Fujii E, Fujii T, Miyazaki H, Yoshino O, Yoshimura K, Maeda T, Kudo Y, Kobayashi H.
- Journal Title
  
  The Journal of Obstetrics and Gynecology Research
  
  Volume: 47 Issue: 1 Pages: 5-25
- DOI
  10.1111/jog.14487
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10488, KAKENHI-PROJECT-19K09823
[Journal Article] Sphingosine 1-Phosphate (S1P) in the Peritoneal Fluid Skews M2 Macrophage and Contributes to the Development of Endometriosis.2021
- Author(s)
  Ono Y., Kawakita T., Yoshino O., Sato E., Kano K., Ohba M., Okuno T., Ito M., Koga K., Honda M., Furue A., Hiraoka T., Wada S., Iwasa T., Yokomizo T., Aoki J., Maeda N., Unno N., Osuga Y., Hirata S.
- Journal Title
  
  Biomedicines
  
  Volume: 9(11) Issue: 11 Pages: 1519-1519
- DOI
  10.3390/biomedicines9111519
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07357, KAKENHI-PROJECT-21H04798, KAKENHI-PROJECT-19K09823, KAKENHI-PROJECT-21K09510, KAKENHI-PROJECT-19KK0199
[Journal Article] CD206+?macrophage is an accelerator of endometriotic-like lesion via promoting angiogenesis in the endometriosis mouse model2021
- Author(s)
  Ono Yosuke、Yoshino Osamu、Hiraoka Takehiro、Sato Erina、Furue Akiko、Nawaz Allah、Hatta Hideki、Fukushi Yoshiyuki、Wada Shinichiro、Tobe Kazuyuki、Hirota Yasushi、Osuga Yutaka、Unno Nobuya、Saito Shigeru
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 853-853
- DOI
  10.1038/s41598-020-79578-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16022, KAKENHI-PROJECT-20K22733, KAKENHI-PROJECT-19H03796, KAKENHI-PROJECT-19H03144, KAKENHI-PROJECT-19K09823
[Journal Article] Perinatal outcomes associated with the positional relationship between the placenta and the adenomyosis lesion2021
- Author(s)
  Ono Yosuke、Ota Hajime、Takimoto Kanako、Tsuzuki Yoko、Nakajima Ayako、Yoshino Osamu、Unno Nobuya、Fujino Takafumi、Fukushi Yoshiyuki、Wada Shinichiro
- Journal Title
  
  Journal of Gynecology Obstetrics and Human Reproduction
  
  Volume: 50 Issue: 7 Pages: 102114-102114
- DOI
  10.1016/j.jogoh.2021.102114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09823
[Journal Article] Uterine CD11c+ cells induce the development of paternal antigen-specific Tregs via seminal plasma priming2020
- Author(s)
  Shima Tomoko、Nakashima Akitoshi、Yasuda Ippei、Ushijima Akemi、Inada Kumiko、Tsuda Sayaka、Yoshino Osamu、Tomura Michio、Saito Shigeru
- Journal Title
  
  Journal of Reproductive Immunology
  
  Volume: - Pages: 103165-103165
- DOI
  10.1016/j.jri.2020.103165
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11221, KAKENHI-PROJECT-19K09750, KAKENHI-PROJECT-19K09823, KAKENHI-PROJECT-20K09614, KAKENHI-PROJECT-19K18690
[Journal Article] Bone morphogenetic protein‐2 enhances gonadotropin‐independent follicular development via sphingosine kinase 12020
- Author(s)
  Ito Masami、Yoshino Osamu、Ono Yosuke、Yamaki‐Ushijima Akemi、Tanaka Tomoko、Shima Tomoko、Orisaka Makoto、Iwase Akira、Nakashima Akitoshi、Saito Shigeru
- Journal Title
  
  American Journal of Reproductive Immunology
  
  Volume: 85 Issue: 5
- DOI
  10.1111/aji.13374
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09224, KAKENHI-PROJECT-19K09750, KAKENHI-PROJECT-19K09823
[Journal Article] CD206+ M2-like Macrophages are Essential for Successful Implantation.2020
- Author(s)
  Ono Y, Yoshino O, Ushijima A, Hiraoka T, Fukui Y, Nawaz A, Hirota Y, Wada S, Tobe K, Nakashima A, Osuga Y and Saito S.
- Journal Title
  
  Front Immunol.
  
  Volume: 11 Pages: 557184-557184
- DOI
  10.3389/fimmu.2020.557184
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09750, KAKENHI-PROJECT-19K09823, KAKENHI-PROJECT-20K22733, KAKENHI-PROJECT-19H03796, KAKENHI-PROJECT-19H03144
[Journal Article] Differential roles of uterine epithelial and stromal STAT3 coordinate uterine receptivity and embryo attachment2020
- Author(s)
  Hiraoka Takehiro、Hirota Yasushi、Fukui Yamato、Gebril Mona、Kaku Tetsuaki、Aikawa Shizu、Hirata Tomoyuki、Akaeda Shun、Matsuo Mitsunori、Haraguchi Hirofumi、Saito-Kanatani Mayuko、Shimizu-Hirota Ryoko、Takeda Norihiko、Yoshino Osamu、Fujii Tomoyuki、Osuga Yutaka
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 15523-15523
- DOI
  10.1038/s41598-020-72640-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09823, KAKENHI-PROJECT-19K16022, KAKENHI-PROJECT-19H03796, KAKENHI-PROJECT-20J11585, KAKENHI-PROJECT-19K18630, KAKENHI-PROJECT-19K18631, KAKENHI-PROJECT-20K22732, KAKENHI-PROJECT-19H03144
[Journal Article] Inhibition of autophagy in theca cells induces CYP17A1 and PAI-1 expression via ROS/p38 and JNK signalling during the development of polycystic ovary syndrome2020
- Author(s)
  Kobayashi Mutsumi、Yoshino Osamu、Nakashima Akitoshi、Ito Masami、Nishio Kazuyuki、Ono Yosuke、Kusabiraki Tae、Kunitomi Chisato、Takahashi Nozomi、Harada Miyuki、Hattori Katsushige、Orisaka Makoto、Osuga Yutaka、Saito Shigeru
- Journal Title
  
  Molecular and Cellular Endocrinology
  
  Volume: 15 Pages: 110792-110792
- DOI
  10.1016/j.mce.2020.110792
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09750, KAKENHI-PROJECT-18K19600, KAKENHI-PROJECT-19K09823
[Journal Article] Sphingosine 1 Phosphate (S1P) Increased IL-6 Expression and Cell Growth in Endometriotic Cells.2019
- Author(s)
  Yoshino O, Yamada-Nomoto K, Kano K, Ono Y, Kobayashi M, Ito M, Yoneda S, Nakashima A, Shima T, Onda T, Osuga Y, Aoki J, Saito S.
- Journal Title
  
  Reprod Sci.
  
  Volume: 1933719119828112 Issue: 11 Pages: 1460-1467
- DOI
  10.1177/1933719119828112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09251, KAKENHI-PROJECT-19K09823, KAKENHI-PROJECT-16H05469
[Journal Article] Risk factors of stress fractures due to the female athlete triad: Differences in teens and twenties.2019
- Author(s)
  Nose-Ogura S, Yoshino O, Dohi M, Kigawa M, Harada M, Hiraike O, Onda T, Osuga Y, Fujii T, Saito S.
- Journal Title
  
  Scand J Med Sci Sports.
  
  Volume: 29(10): Issue: 10 Pages: 1501-1510
- DOI
  10.1111/sms.13464
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09823
[Journal Article] Endometriosis Triggers Excessive Activation of Primordial Follicles via PI3K-PTEN-Akt-Foxo3 Pathway2019
- Author(s)
  Takeuchi Arisa、Koga Kaori、Satake Erina、Makabe Tomoko、Taguchi Ayumi、Miyashita Mariko、Takamura Masashi、Harada Miyuki、Hirata Tetsuya、Hirota Yasushi、Yoshino Osamu、Wada-Hiraike Osamu、Fujii Tomoyuki、Osuga Yutaka
- Journal Title
  
  The Journal of Clinical Endocrinology & Metabolism
  
  Volume: 104 Issue: 11 Pages: 5547-5554
- DOI
  10.1210/jc.2019-00281
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09221, KAKENHI-PROJECT-18K09248, KAKENHI-PROJECT-19K09749, KAKENHI-PROJECT-19K09823, KAKENHI-PROJECT-18K19601, KAKENHI-PROJECT-18K16757, KAKENHI-PROJECT-18K16758, KAKENHI-PROJECT-16H04679, KAKENHI-PROJECT-16H05469, KAKENHI-PROJECT-19H03144
[Journal Article] Serum Brain-derived Neurotrophic Factor Levels Mirror Bone Mineral Density in Amenorrheic and Eumenorrheic Athletes.2019
- Author(s)
  Nose S, Yoshino O, Nomoto K, Harada M, Dohi M, Kawahara T, Osuga Y, Fujii T, Saito S.
- Journal Title
  
  Int J Sports Med.
  
  Volume: 40(4) Issue: 04 Pages: 276-282
- DOI
  10.1055/a-0835-6119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09823, KAKENHI-PROJECT-16H05469
[Journal Article] Expression of Nerve Injury-Induced Protein1 (Ninj1) in Endometriosis2018
- Author(s)
  Miyashita Mariko、Koga Kaori、Takeuchi Arisa、Makabe Tomoko、Taguchi Ayumi、Urata Yoko、Izumi Gentaro、Takamura Masashi、Harada Miyuki、Hirata Tetsuya、Hirota Yasushi、Wada-Hiraike Osamu、Yoshino Osamu、Fujii Tomoyuki、Osuga Yutaka
- Journal Title
  
  Reproductive Sciences
  
  Volume: in press Issue: 8 Pages: 368-375
- DOI
  10.1177/1933719118806395
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09221, KAKENHI-PROJECT-18K09248, KAKENHI-PROJECT-19K09823, KAKENHI-PROJECT-19H03796, KAKENHI-PROJECT-18K16758, KAKENHI-PROJECT-16H04679, KAKENHI-PROJECT-16H05469, KAKENHI-PROJECT-19H03144
[Journal Article] PAI-1 in granulosa cells is suppressed directly by statin and indirectly by suppressing　TGF-β and TNF-α in mononuclear cells by insulin-sensitizing drugs.2017
- Author(s)
  Yamada-Nomoto K, Yoshino O, Akiyama I, Iwase A, Ono Y, Nakamura T, Harada M, Nakashima A, Shima T, Ushijima A, Osuga Y, Chang RJ, Shimasaki S, Saito S.
- Journal Title
  
  Am J Reprod Immunol.
  
  Volume: 78 Issue: 1 Pages: 1-8
- DOI
  10.1111/aji.12669
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462479, KAKENHI-PROJECT-15H04984
[Journal Article] A Potential Role for Endoplasmic Reticulum Stress in Progesterone Deficiency in Obese Women.2017
- Author(s)
  Takahashi N, Harada M, Hirota Y, Zhao L, Azhary JM, Yoshino O, Izumi G, Hirata T, Koga K, Wada-Hiraike O, Fujii T, Osuga Y.
- Journal Title
  
  Endocrinology
  
  Volume: 158 Pages: 84-97
- DOI
  10.1210/en.2016-1511
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04679, KAKENHI-PROJECT-16H05469, KAKENHI-PROJECT-26462476, KAKENHI-PROJECT-26462477, KAKENHI-PROJECT-26462479, KAKENHI-PROJECT-15K10660, KAKENHI-PROJECT-15K10704, KAKENHI-PROJECT-16K15700, KAKENHI-PROJECT-16K15701
[Journal Article] Oral contraceptive therapy reduces serum　relaxin-2 in elite female athletes.2017
- Author(s)
  Nose-Ogura S, Yoshino O, Yamada-Nomoto K, Nakamura M, Harada M, Dohi M, Okuwaki T, Osuga Y, Kawahara T, Saito S.
- Journal Title
  
  J Obstet Gynaecol Res.
  
  Volume: 43 Issue: 3 Pages: 530-5
- DOI
  10.1111/jog.13226
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462479
[Journal Article] A new era in reproductive medicine: consequences of third-party oocyte donation for maternal and fetal health.2016
- Author(s)
  Saito S, Nakabayashi Y, Nakashima A, Shima T, Yoshino O.
- Journal Title
  
  Semin Immunopathol.
  
  Volume: 38 Pages: 687-697
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462479
[Journal Article] A potential role of endoplasmic reticulum stress in development of ovarian hyperstimulation syndrome.2016
- Author(s)
  Takahashi N, Harada M, Hirota Y, Zhao L, Yoshino O, Urata Y, Izumi G, Takamura M, Hirata T, Koga K, Wada-Hiraike O, Fujii T, Osuga Y.
- Journal Title
  
  Mol Cell Endocrinol
  
  Volume: 428 Pages: 161-169
- DOI
  10.1016/j.mce.2016.03.032
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26112506, KAKENHI-PUBLICLY-26112703, KAKENHI-PROJECT-15K15596, KAKENHI-PROJECT-15K15597, KAKENHI-PROJECT-24689062, KAKENHI-PROJECT-16H04679, KAKENHI-PROJECT-16H05469, KAKENHI-PROJECT-26462476, KAKENHI-PROJECT-26462477, KAKENHI-PROJECT-26462479, KAKENHI-PROJECT-16K20177, KAKENHI-PROJECT-15K10660, KAKENHI-PROJECT-15K10704, KAKENHI-PROJECT-16K15700, KAKENHI-PROJECT-16K15701, KAKENHI-ORGANIZER-25112001
[Journal Article] The assessment of myometrium perfusion in patients with uterine fibroid by arterial spin labeling MRI.2016
- Author(s)
  Takahashi N, Yoshino O, Hiraike O, Maeda E, Nakamura M, Hori M, Harada M, Koga K, Saito S, Fujii T, Osuga Y.
- Journal Title
  
  Springerplus.
  
  Volume: 5 Pages: 1907-1907
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462479
[Journal Article] Alpha-7 nicotinic acetylcholine receptor (nAChR) agonist inhibits the development of endometriosis by regulating inflammation.2016
- Author(s)
  Yamada-Nomoto K, Yoshino O, Akiyama I, Ushijima A, Ono Y, Shima T, Nakashima A, Hayashi S, Kadowaki M, Osuga Y, Saito S.
- Journal Title
  
  Am J Reprod Immunol.
  
  Volume: 76 Issue: 6 Pages: 491-498
- DOI
  10.1111/aji.12592
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462479, KAKENHI-PROJECT-15K18873
[Journal Article] Role of Paternal Antigen-Specific Treg Cells in Successful Implantation.2016
- Author(s)
  Saito S, Shima T, Nakashima A, Inada K, Yoshino O.
- Journal Title
  
  Am J Reprod Immunol.
  
  Volume: 75 Issue: 3 Pages: 310-316
- DOI
  10.1111/aji.12469
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462479, KAKENHI-PROJECT-15H04980
[Journal Article] Usefulness of T2 star-weighted imaging in ovarian cysts and tumors.2016
- Author(s)
  Takahashi N, Yoshino O, Maeda E, Naganawa S, Harada M, Koga K, Hiraike O, Nakamura M, Tabuchi T, Hori M, Saito S, Fujii T, Osuga Y.
- Journal Title
  
  J Obstet Gynaecol Res
  
  Volume: 42 Issue: 10 Pages: 1336-1342
- DOI
  10.1111/jog.13056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05469, KAKENHI-PROJECT-26462476, KAKENHI-PROJECT-26462479, KAKENHI-PROJECT-16K15700
[Journal Article] Evidence of the activation of unfolded protein response in granulosa and cumulus cells during follicular growth and maturation.2015
- Author(s)
  Harada, M., Nose, E., Takahashi, N., Hirota, Y., Hirata, T., Yoshino, O., Koga, K., Fujii, T., Osuga, Y
- Journal Title
  
  Gynecological Endocrinology
  
  Volume: 31 Issue: 10 Pages: 783-787
- DOI
  10.3109/09513590.2015.1062862
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10660, KAKENHI-PROJECT-26462476, KAKENHI-PROJECT-26462477, KAKENHI-PROJECT-26462479, KAKENHI-ORGANIZER-25112001, KAKENHI-PUBLICLY-26112506, KAKENHI-PUBLICLY-26112703, KAKENHI-PROJECT-15K15596, KAKENHI-PROJECT-15K15597, KAKENHI-PROJECT-24689062
[Journal Article] Paternal antigen-specific proliferating regulatory T cells are increased in uterine-draining lymph nodes just before implantation and in pregnant uterus just after implantation by seminal plasma-priming in allogeneic mouse pregnancy.2015
- Author(s)
  Shima T, Inada K, Nakashima A, Ushijima A, Ito M, Yoshino O, Saito S.
- Journal Title
  
  J Reprod Immunol.
  
  Volume: 108 Pages: 78-82
- DOI
  10.1016/j.jri.2015.02.005
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23390386, KAKENHI-PROJECT-26462479, KAKENHI-PROJECT-15H04980, KAKENHI-PROJECT-26861316
[Journal Article] 子宮因子による不妊2014
- Author(s)
  吉野　修、齋藤　滋
- Journal Title
  
  産婦人科の実際
  
  Volume: 63 Pages: 1535-1539
- Data Source
  KAKENHI-PROJECT-26462479
[Journal Article] 不妊症と子宮筋腫2014
- Author(s)
  吉野　修、齋藤　滋
- Journal Title
  
  産婦人科の実際
  
  Volume: 63 Pages: 1387-1391
- Data Source
  KAKENHI-PROJECT-26462479
[Journal Article] 治療を見据えた子宮筋腫の画像評価2014
- Author(s)
  吉野　修、齋藤　滋
- Journal Title
  
  臨床婦人科産科
  
  Volume: 68 Pages: 202-208
- Data Source
  KAKENHI-PROJECT-26462479
[Journal Article] Application of detergents or high hydrostatic pressure as decellularization process in uterine tissues and their subsequent effects on in vivo uterine regeneration in murine models2014
- Author(s)
  E.G.Santoso, K.Yoshida, Y.Hirota, M.Aizawa,O.Yoshino, A.Kishida, Y.Osuga, S.Saito, T.Ushida, K.S.Furukawa,
- Journal Title
  
  PLoS ONE
  
  Volume: 9 Issue: 7 Pages: 1-13
- DOI
  10.1371/journal.pone.0103201
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23300177, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-25670695, KAKENHI-PUBLICLY-26112506, KAKENHI-PUBLICLY-26112703, KAKENHI-PROJECT-26462479, KAKENHI-PROJECT-26670713, KAKENHI-PROJECT-26670714, KAKENHI-PROJECT-24689062
[Journal Article] IL-1β increases expression of tryptophan 2,3-dioxygenase and stimulates tryptophan catabolism in endometrioma stromal cells.2014
- Author(s)
  Urata Y, Koga K, Hirota Y, Akiyama I, Izumi G, Takamura M, Nagai M, Harada M, Hirata T, Yoshino O, Kawana K, Fujii T, Osuga Y.
- Journal Title
  
  Am J Reprod Immunol.
  
  Volume: 72 Issue: 5 Pages: 496-503
- DOI
  10.1111/aji.12282
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670695, KAKENHI-PROJECT-25861472, KAKENHI-PUBLICLY-26112506, KAKENHI-PUBLICLY-26112703, KAKENHI-PROJECT-26462476, KAKENHI-PROJECT-26462477, KAKENHI-PROJECT-26462478, KAKENHI-PROJECT-26462479, KAKENHI-PROJECT-26670713, KAKENHI-PROJECT-26670714, KAKENHI-PROJECT-24689062
[Journal Article] Bone morphogenetic protein 7 increased vascular endothelial growth factor (VEGF)-a expression in human granulosa cells and VEGF receptor expression in endothelial cells.2014
- Author(s)
  Akiyama I, Yoshino O et al.
- Journal Title
  
  Reprod Sci.
  
  Volume: 21(4) Issue: 4 Pages: 477-82
- DOI
  10.1177/1933719113503411
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791687, KAKENHI-PROJECT-24791689, KAKENHI-PROJECT-25670695, KAKENHI-PUBLICLY-26112506, KAKENHI-PUBLICLY-26112703, KAKENHI-PROJECT-26462476, KAKENHI-PROJECT-26462477, KAKENHI-PROJECT-26670713, KAKENHI-PROJECT-24689062
[Journal Article] Application of detergents or high hydrostatic pressure as decellularization processes in uterine tissues and their subsequent effects on in vivo uterine regeneration in murine models2014
- Author(s)
  Erna G. Santoso, Keita Yoshida, Yasushi Hirota, Masanori Aizawa, Osamu Yoshino, Akio Kishida, Yutaka Osuga, Shigeru Saito, Takashi Ushida, Katsuko S. Furukawa
- Journal Title
  
  PLOS ONE
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25560191
[Journal Article] Serum concntration of bone morphogenetic proteins (BMPs) is not linked to serum anti-mullerian hormomne (AMH) level.2014
- Author(s)
  Sayaka Ogura-Nose, Osamu Yoshino, Ikumi Akiyama, Yasushi Hirota, Tetsuya Hirata,Miyuki Harada, Hisahiko Hiroi, KaoriKoga, Shigeru Saito, Yutaka Osuga, Tomoyuki Fujii
- Journal Title
  
  Integrative Molecular Medicine
  
  Volume: 1 Pages: 26-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462479
[Journal Article] 特集ＣＴ、ＭＲＩ戦略的　活用ガイド2014
- Author(s)
  吉野　修、齋藤　滋
- Journal Title
  
  medicina
  
  Volume: 51 Pages: 336-7
- Data Source
  KAKENHI-PROJECT-26462479
[Journal Article] A first case report of torsion of the substituted small intestine 39 years after vaginoplasty using ileum segment.2014
- Author(s)
  Yosuke Ono, Osamu Yoshino, Masami Ito, Sho Soeda, Tomoko Shima and Shigeru Saito
- Journal Title
  
  Med J Obstet Gyneco
  
  Volume: 2 Pages: 1041-1041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462479
[Journal Article] Application of detergents or high hydrostatic pressure as decellularization processes in uterine tissues and their subsequent effects on in vivo uterine regeneration in murine models2014
- Author(s)
  Erna G. Santoso, Keita Yoshida, Yasushi Hirota, Masanori Aizawa, Osamu Yoshino, Akio Kishida, Yutaka Osuga, Shigeru Saito, Takashi Ushida, Katsuko S. Furukawa
- Journal Title
  
  PLoS ONE
  
  Volume: 9(7)
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25560191
[Journal Article] The Role of Bone Morphogenetic Protein 6 in Accumulation and Regulation of Neutrophils in the Human Ovary.2014
- Author(s)
  Akiyama I, Yoshino O et al.
- Journal Title
  
  Reprod Sci.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791687
[Journal Article] 子宮内膜症治療の未来図　手術と薬物療法のコンビネーション2014
- Author(s)
  吉野　修、高村　将司、甲賀かをり、大須賀　穣、齋藤　滋
- Journal Title
  
  臨床婦人科産科
  
  Volume: 68 Pages: 1183-1187
- Data Source
  KAKENHI-PROJECT-26462479
[Journal Article] Follistatin is induced by IL-1β and TNF-α in stromal cells from endometrioma2013
- Author(s)
  Akiyama I, Yoshino O, Osuga Y, Izumi G, Urata Y, Hirota Y, Hirata T, Harada M, Koga K, Ogawa K, Kozuma S
- Journal Title
  
  Reprod Sci
  
  Volume: 20(6) Pages: 675-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791687
[Journal Article] Cyclic stretch augments production of neutrophil chemokines and matrix metalloproteinase-1 in human uterine smooth muscle cells2013
- Author(s)
  Zhao Y, Koga K, Osuga Y, Izumi G, Takamura M, Harada M, Hirata T, Hirota Y, Yoshino O, Fujii T, Kozuma S
- Journal Title
  
  Am J Reprod Immunol
  
  Volume: 69(3) Pages: 240-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791687
[Journal Article] Cyclic stretch augments production of neutrophil chemokines and matrix metalloproteinases-1 (MMP-1) from human decidual cells, and the production was reduced by progesterone2013
- Author(s)
  Zhao Y, Koga K, Osuga Y, Izumi G, Takamura M, Harada M, Hirata T, Hirota Y, Yoshino O, Inoue S, Fujii T, Kozuma S
- Journal Title
  
  Am J Reprod Immunol
  
  Volume: 69(5) Pages: 454-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791687
[Journal Article] Interleukin-4 and prostaglandin E2 synergistically up-regulate 3β-hydroxysteroid dehydrogenase type 2 in endometrioma stromal cells2013
- Author(s)
  Urata Y, Osuga Y, Akiyama I, Nagai M, Izumi G, Takamura M, Hasegawa A, Harada M, Hirata T, Hirota Y, Yoshino O, Koga K, Kozuma S
- Journal Title
  
  J Clin Endocrinol Metab
  
  Volume: 98(4) Issue: 4 Pages: 1583-90
- DOI
  10.1210/jc.2012-3475
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592395, KAKENHI-PROJECT-23791813, KAKENHI-PROJECT-24689062, KAKENHI-PROJECT-24791687, KAKENHI-PROJECT-24791689, KAKENHI-PROJECT-24791691, KAKENHI-PROJECT-25670695
[Journal Article] Cyclic stretch augments production of neutrophil chemokines and matrix metalloproteinase-1 in human uterine smooth muscle cells.2013
- Author(s)
  Zhao Y1, Koga K, Osuga Y, Izumi G, Takamura M, Harada M, Hirata T, Hirota Y, Yoshino O, Fujii T, Kozuma S.
- Journal Title
  
  Am J Reprod Immunol.
  
  Volume: 69 Issue: 3 Pages: 240-7
- DOI
  10.1111/aji.12061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592396, KAKENHI-PROJECT-24689062, KAKENHI-PROJECT-24791687, KAKENHI-PROJECT-24791691
[Journal Article] Interleukin-4 and prostaglandin E2 synergistically up-regulate 3β-hydroxysteroid dehydrogenase type 2 in endometrioma stromal cells2013
- Author(s)
  Urata Y, Osuga Y, Akiyama I, Nagai M, Izumi G, Takamura M, Hasegawa A, Harada M, Hirata T, Hirota Y, Yoshino O, Koga K, Kozuma S
- Journal Title
  
  J Clin Endocrinol Metab
  
  Volume: 98(4) Pages: 1583-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791687
[Journal Article] 子宮内膜症におけるブラジキニンに関する検討2013
- Author(s)
  吉野修
- Journal Title
  
  産科と婦人科
  
  Volume: vol. 80 No 11 Pages: 1509-1510
- Data Source
  KAKENHI-PROJECT-24791687
[Journal Article] Follistatin is induced by IL-1βand TNF-αin stromal cells from endometrioma2013
- Author(s)
  Akiyama I, Yoshino O, Osuga Y, Izumi G, Urata Y, Hirota Y, Hirata T, Harada M, Koga K, Ogawa K, Kozuma S
- Journal Title
  
  Reprod Sci
  
  Volume: 20(6) Issue: 6 Pages: 675-9
- DOI
  10.1177/1933719112463253
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592395, KAKENHI-PROJECT-24580440, KAKENHI-PROJECT-24689062, KAKENHI-PROJECT-24791687, KAKENHI-PROJECT-24791691, KAKENHI-PROJECT-25670695
[Journal Article] Cyclic Stretch Augments Production of Neutrophil Chemokines and Matrix Metalloproteinases-1 (MMP-1) from Human Decidual Cells, and the Production was Reduced by Progesterone.2013
- Author(s)
  Zhao Y, Koga K, Osuga Y, Izumi G, Takamura M, Harada M, Hirata T, Hirota Y, Yoshino O, Inoue S, Fujii T, Kozuma S
- Journal Title
  
  Am J Reprod Immunol
  
  Volume: 69 Issue: 5 Pages: 454-462
- DOI
  10.1111/aji.12092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249040, KAKENHI-PROJECT-23592396, KAKENHI-PROJECT-24689062, KAKENHI-PROJECT-24791687, KAKENHI-PROJECT-24791689, KAKENHI-PROJECT-24791691, KAKENHI-PROJECT-25670695
[Journal Article] 子宮内膜症におけるブラジキニンに関する検討2013
- Author(s)
  吉野　修
- Journal Title
  
  産科と婦人科
  
  Volume: Vol.80 No.11 Pages: 1509-1510
- Data Source
  KAKENHI-PROJECT-24791687
[Journal Article] The significance of serum anti-Müllerian hormone (AMH) levels in patients over age 40 in first IVF treatment2013
- Author(s)
  Tokura Y, Yoshino O, Ogura-Nose S, Motoyama H, Harada M, Osuga Y, Shimizu Y, Ohara M, Yorimitsu T, Nishii O, Kozuma S, Kawamura T
- Journal Title
  
  J Assist Reprod Genet
  
  Volume: 30(6) Pages: 821-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791687
[Journal Article] Interleukin-1β stimulates the secretion of thymic stromal lymphopoietin (TSLP) from endometrioma stromal cells: possible involvement of TSLP in endometriosis.2012
- Author(s)
  Urata Y, Osuga Y, Izumi G, Takamura M, Koga K, Nagai M, Harada M, Hirata T, Hirota Y, Yoshino O, Taketani Y.
- Journal Title
  
  Hum Reprod.
  
  Volume: 27 Pages: 3028-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791687
[Journal Article] Interleukin-17A is present in neutrophils in endometrioma and stimulates the secretion of growth-regulated oncogene-α (Gro-α) from endometrioma stromal cells2012
- Author(s)
  Takamura M, Osuga Y, Izumi G, Yoshino O, Koga K, Saito A, Hirata T, Hirota Y, Harada M, Hasegawa A, Taketani Y
- Journal Title
  
  Fertil Steril
  
  Volume: 98 Issue: 5 Pages: 1218-24
- DOI
  10.1016/j.fertnstert.2012.07.1117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592395, KAKENHI-PROJECT-23791813, KAKENHI-PROJECT-24689062, KAKENHI-PROJECT-24791687, KAKENHI-PROJECT-24791689
[Journal Article] Interleukin-1β stimulates the secretion of thymic stromal lymphopoietin (TSLP) from endometrioma stromal cells : possible involvement of TSLP in endometriosis2012
- Author(s)
  Urata Y, Osuga Y, Izumi G, Takamura M, Koga K, Nagai M, Harada M, Hirata T, Hirota Y, Yoshino O, Taketani Y
- Journal Title
  
  Hum Reprod
  
  Volume: 27(10) Pages: 3028-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791687
[Journal Article] Thrombin enhances soluble Fms-like tyrosine kinase 1 expression in trophoblasts; possible involvement in the pathogenesis of preeclampsia.2012
- Author(s)
  Zhao Y, Koga K, Osuga Y, Nagai M, Izumi G, Takamura M, Harada M, Hirota Y, Yoshino O, Taketani Y
- Journal Title
  
  Fertil Steril
  
  Volume: 98 Issue: 4 Pages: 917-21
- DOI
  10.1016/j.fertnstert.2012.06.038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592396, KAKENHI-PROJECT-24689062, KAKENHI-PROJECT-24791687
[Journal Article] Anti-Mullerian hormone (AMH) is induced by bone morphogenetic protein (BMP) cytokines in human granulosa cells2012
- Author(s)
  Ogura-Nose S, Yoshino O, Osuga Y, Shi J, Hiroi H, Yano T, Taketani Y
- Journal Title
  
  Eur J Obstet Gynecol Reprod Biol
  
  Volume: 164(1) Pages: 44-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791687
[Journal Article] Anti-Mullerian hormone (AMH) is induced by bone morphogenetic protein (BMP) cytokines in human granulosa cells.2012
- Author(s)
  Ogura-Nose S, Yoshino O, Osuga Y, Shi J, Hiroi H, Yano T, Taketani Y.
- Journal Title
  
  Eur J Obstet Gynecol Reprod Biol.
  
  Volume: 164 Issue: 1 Pages: 44-7
- DOI
  10.1016/j.ejogrb.2012.05.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791687
[Journal Article] The localization and regulation of proprotein convertase subtilisin/kexin (PCSK) 6 in human ovary2012
- Author(s)
  Akiyama I, Yoshino O, Osuga Y, Shi J, Hirota Y, Hirata T, Harada M, Koga K, Fujimoto A, Yano T, Taketani Y
- Journal Title
  
  Am J Reprod Immunol
  
  Volume: 68(6) Pages: 491-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791687
[Journal Article] Interleukin-17A is present in neutrophils in endometrioma and stimulates the secretion of growth-regulated oncogene-α (Gro-α) from endometrioma stromal cells2012
- Author(s)
  Takamura M, Osuga Y, Izumi G, Yoshino O, Koga K, Saito A, Hirata T, Hirota Y, Harada M, Hasegawa A, Taketani Y
- Journal Title
  
  Fertil Steril
  
  Volume: 98(5)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791687
[Journal Article] Thrombin enhances soluble Fms-like tyrosine kinase 1 expression in trophoblasts; possible involvement in the pathogenesis of preeclampsia2012
- Author(s)
  Zhao Y, Koga K, Osuga Y, Nagai M, Izumi G, Takamura M, Harada M, Hirota Y, Yoshino O, Taketani Y
- Journal Title
  
  Fertil Steril
  
  Volume: 98(4) Pages: 917-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791687
[Presentation] 日本人月経困難症患者を対象としたQOL・労働生産性に関するePRO研究2021
- Author(s)
  吉野修, 高橋法子, 鈴鴨よしみ
- Organizer
  日本女性医学学会
- Data Source
  KAKENHI-PROJECT-19K09823
[Presentation] RAMP1受容体シグナルによる子宮内膜症進展制御機構2021
- Author(s)
  本田雅子, 伊藤義也, 服部響子, 関口和企, 吉野修, 岩瀬春子, 海野信也
- Organizer
  日本産科婦人科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09823
[Presentation] 生殖内分泌学　基礎から臨床へ2021
- Author(s)
  吉野　修
- Organizer
  関東連合産科婦人科学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K09823
[Presentation] 子宮内膜症性嚢胞の鑑別におけるMRI IDEAL IQの有用性についての検討2021
- Author(s)
  古江明子, 平岡毅大, 本田雅子, 岩端俊輔, 吉野修, 岩瀬春子, 海野信也
- Organizer
  日本産科婦人科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09823
[Presentation] The involvement of Damage-associated molecular patterns (DAMPs) and macrophages in the etiology of endometriosis.2019
- Author(s)
  Osamu Yoshino, Yosuke Ono, Nobuya Unno, Onda Takashi, Shigeru Saito and Yutaka Osuga
- Organizer
  ASRI meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09823
[Presentation] From where the inflammation comes?2019
- Author(s)
  O. Yoshino, Y. Ono, N. Unno, T. Onda, Y Osuga and S. Saito
- Organizer
  ISIR meeting 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09823
[Presentation] 脱細胞化担体への間葉系幹細胞播種による子宮組織再生.2016
- Author(s)
  関護和,小松寛,吉田圭太,金定賢,廣田泰,吉野修,斎藤滋,岸田晶夫,大須賀穣,牛田多加志,古川克子.
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-25560191
[Presentation] 超高静水圧による脱細胞化担体を用いた子宮組織再生.2016
- Author(s)
  関護和,小松寛,吉田圭太,金定賢,廣田泰,吉野修,斉藤滋,岸田晶夫,大須賀穣,牛田多加志,古川克子.
- Organizer
  日本機械学会第28回バイオエンジニアリング講演会
- Place of Presentation
  東京工業大学　大岡山キャンパス（東京都目黒区）
- Year and Date
  2016-01-09
- Data Source
  KAKENHI-PROJECT-25560191
[Presentation] 子宮内膜症病巣におけるS1Pシステムとその作用についての検討2016
- Author(s)
  吉野　修、野本かおり、小野洋輔、中島彰俊、島友子、可野邦行、青木淳賢、齋藤滋
- Organizer
  日本生殖免疫学会総会・学術集会
- Place of Presentation
  神戸
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-26462479
[Presentation] 脱細胞化担体の引張ひずみ印加移植による子宮組織再生2016
- Author(s)
  吉田圭太,関護和,廣田泰,吉野修,齋藤滋,岸田晶夫,大須賀穣,牛田多加志,古川克子.
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-25560191
[Presentation] T2 star 強調MRI画像(T2*)の卵巣病変診断における有用性2016
- Author(s)
  吉野　修、高橋　望、前田　恵理子、大須賀　穣、藤井　知行、齋藤　滋
- Organizer
  北陸生殖医学会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-26462479
[Presentation] Promoted differentiation of smooth muscle cells in hMSCs by cyclic stain via the cAMP pathway.2016
- Author(s)
  Ｊeonghyun Kim,Kevin Montagne,Teemu Mehtonen,Yasushi Hirota,Osamu Yoshino,Shigeru Saito,Yutaka Osuga,Takashi Ushida,Katsuko Furukawa.
- Organizer
  The 15th Congress of Japanese Society for Regenerative Medicine
- Place of Presentation
  International Convention Center（大阪府大阪市）
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-25560191
[Presentation] 1.PAI-1 in granulosa cells is suppressed directly by statin and indirectly by suppressing TGF-β and TNF-α in mononuclear cells by insulin sensitizing drugs.2016
- Author(s)
  Osamu Yoshino, Kaori Yamada-Nomoto, Ikumi Akiyama, Akira Iwase, Akitoshi Nakashima, Tomoko Shima, Yutaka Osuga and Shigeru Saito
- Organizer
  日本産婦人科学会総会
- Place of Presentation
  東京
- Year and Date
  2016-04-22
- Data Source
  KAKENHI-PROJECT-26462479
[Presentation] Cyclic Stretching of Human Endometrial Stromal Cells Promotes Their Differentiation into Smooth Muscle Cells.2015
- Author(s)
  Jeonghyun Kim, Yasushi Hirota, Takehiro Hiraoka, Osamu Yoshino, Kevin Montagne, Masayo Yokota, Shigeru Saito, Yutaka Osuga, Takashi Ushida, Katsuko S Furukawa.
- Organizer
  The 8th Asian-Pacific Conference on Biomechanics,
- Place of Presentation
  Hokkaido University（北海道札幌市）
- Year and Date
  2015-09-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25560191
[Presentation] Uterine tissue engineering by applying cyclic stretching.2015
- Author(s)
  Jeonghyun Kim, Kevin Montagne,Yasushi Hirota, Takehiro Hiraoka, Osamu Yoshino, Masayo Yokota, Shigeru Saito, Yutaka Osuga, Takashi Ushida, Katsuko S Furukawa.
- Organizer
  第53回日本人工臓器学会大会
- Place of Presentation
  東京ドームホテル（東京都文京区）
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-25560191
[Presentation] Cyclic Stretching Promoted cAMP Production in Human Endometrial Stromal Cells Leading to Differentiation into Smooth Muscle Cells.2015
- Author(s)
  Jeonghyun Kim, Kevin Montagne,Yasushi Hirota, Takehiro Hiraoka, Osamu Yoshino, Masayo Yokota, Shigeru Saito, Yutaka Osuga, Takashi Ushida, Katsuko S Furukawa.
- Organizer
  第42回日本臨床バイオメカニクス学会
- Place of Presentation
  ソラシティカンファレンスセンター（東京都文京区）
- Year and Date
  2015-11-13
- Data Source
  KAKENHI-PROJECT-25560191
[Presentation] 子宮内膜症病巣におけるブラジキニン受容体の発現と作用に関する検討2015
- Author(s)
  吉野　修、野本かおり、小野洋輔、長谷川亜希子、大須賀　穣、齋藤　滋
- Organizer
  第30回日本生殖免疫学会総会・学術集会
- Place of Presentation
  熊本
- Year and Date
  2015-11-21
- Data Source
  KAKENHI-PROJECT-26462479
[Presentation] 多嚢性卵巣症候群(PCOS)に関与する因子plasminogen activator inhibitor-1 (PAI-1)の制御に関する検討。2015
- Author(s)
  吉野　修、岩瀬　明、秋山　育美、島　友子、大須賀　穣、齋藤　滋1
- Organizer
  第６７回日本産婦人科学会総会
- Place of Presentation
  横浜
- Year and Date
  2015-04-09
- Data Source
  KAKENHI-PROJECT-26462479
[Presentation] 動的培養による子宮組織の再構築2014
- Author(s)
  渡辺翔太, 小林一穂, Gondo Santoso Erna, 廣田泰, 吉田圭太, 吉野修, 斉藤滋, 大須賀穣, 牛田多加志, 古川克子
- Organizer
  日本機械学会関東支部第20期総会・講演会
- Place of Presentation
  東京農工大学小金井キャンパス（東京都）
- Data Source
  KAKENHI-PROJECT-25560191
[Presentation] 脱細胞組織担体を用いたラット子宮組織の再生2014
- Author(s)
  吉田圭太，Erna Gondo Santoso，廣田泰，吉野修，根岸淳，岸田晶夫，齋藤滋，大須賀穣，牛田多加志，古川克子
- Organizer
  日本機械学会第26回バイオエンジニアリング講演会
- Place of Presentation
  東北大学片平キャンパス（宮城県）
- Data Source
  KAKENHI-PROJECT-25560191
[Presentation] Reconstruction of rat uterine tissue using a decellularized tissue scaffold2014
- Author(s)
  Erna G. Santoso, Keita Yoshida, Yasushi Hirota, Masanori Aizawa, Osamu Yoshino, Akio Kishida, Yutaka Osuga, Shigeru Saito, Takashi Ushida, Katsuko S. Furukawa
- Organizer
  第１３回日本再生医療学会総会
- Place of Presentation
  国立京都国際会館（京都府）
- Data Source
  KAKENHI-PROJECT-25560191
[Presentation] MRIを用いた子宮筋腫の新たな評価法2013
- Author(s)
  吉野　修
- Organizer
  第４回婦人科ホルモン依存性疾患研究会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-24791687
[Presentation] 筋層内子宮筋腫により誘導される子宮内膜の異常蠕動は妊娠率を低下させる。2013
- Author(s)
  吉野　修、齋藤滋、　西井　修、折坂　誠
- Organizer
  第４１回　北陸産婦人科学会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-24791687
[Presentation] "子宮筋腫核出術は子宮内膜のT2値を低下させる。 "2013
- Author(s)
  吉野　修、　齋藤　滋、西井　修
- Organizer
  第61回　北日本産婦人科学会
- Place of Presentation
  旭川
- Data Source
  KAKENHI-PROJECT-24791687
[Presentation] 卵巣顆粒膜細胞におけるAMHの発現はbone morphogenetic protein (BMP)サイトカインにより制御される。2013
- Author(s)
  吉野　修、能瀬　さやか　ら
- Organizer
  第28回日本生殖免疫学会総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24791687
[Presentation] ４０歳以上の初回IVF-ET症例における血中anti-Müllerian hormone (AMH)の意義に関する検討。
- Author(s)
  吉野　修、能瀬　さやか、副田　翔、西井　修、河村　寿宏、齋藤　滋
- Organizer
  第62回北日本産科婦人科学会　総会・学術講演会
- Place of Presentation
  金沢
- Year and Date
  2014-09-27 – 2014-09-28
- Data Source
  KAKENHI-PROJECT-26462479
[Presentation] 静水圧または薬剤処理による脱細胞化子宮の再生
- Author(s)
  Furukawa KS, Santoso EG, Yoshida K, Hirota Y, Aizawa M, Yoshino O, Kishida A, Osuga Y, Saito S, Ushida T
- Organizer
  第１４回日本再生医療学会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2015-03-19 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-25560191
[Presentation] 基礎的見地から卵巣生理・病理学における顆粒膜細胞と周辺細胞との関連についての検討
- Author(s)
  吉野　修
- Organizer
  第29回日本生殖免疫学会総会・学術集会シンポジウム
- Place of Presentation
  東京
- Year and Date
  2014-12-12 – 2014-12-13
- Invited
- Data Source
  KAKENHI-PROJECT-26462479
[Presentation] 顆粒膜細胞から産生されるGrowth differentiation factor (GDF)-3 はbone morphogenetic protein (BMP)サイトカインにより誘導され、BMPによるＬＨ受容体発現低下をキャンセルする。
- Author(s)
  1.吉野　修、秋山　育美、大須賀　穣、甲賀かをり、原田　美由紀、齋藤　滋、藤井　知行
- Organizer
  第66回日本産婦人科学会総会
- Place of Presentation
  東京
- Year and Date
  2014-04-18 – 2014-04-20
- Data Source
  KAKENHI-PROJECT-26462479
[Presentation] 脱細胞化担体を用いた子宮組織再生手法の検討
- Author(s)
  吉田圭太，中安愛子，関護和，廣田泰，吉野修，岸田晶夫，齋藤滋，大須賀穣，牛田多加志，古川克子
- Organizer
  日本機械学会第27回バイオエンジニアリング講演会
- Place of Presentation
  朱鷺メッセ（新潟県）
- Year and Date
  2015-01-09 – 2015-01-10
- Data Source
  KAKENHI-PROJECT-25560191
[Presentation] 間葉系幹細胞への分化誘導を目指した再生子宮の構築
- Author(s)
  関護和，渡辺翔太，小松寛，吉田圭太，金定賢，廣田泰，吉野修，斉藤滋，大須賀穣，牛田多加志，古川克子
- Organizer
  日本機械学会関東支部第２１回総会・講演会
- Place of Presentation
  横浜国立大学（神奈川県横浜市）
- Year and Date
  2015-03-20 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-25560191
[]
[]
[]

1. Ushida Takashi (50323522)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
2. Furukawa Katsuko S (90343144)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
3. HIROTA Yasushi (40598653)

# of Collaborated Projects: 1 results

# of Collaborated Products: 20 results
4. KISHIDA Akio (60224929)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
5. 中島彰俊 (00436792)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 酒井康行 (00235128)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 山田秀人 (40220397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 荒瀬尚 (10261900)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 出口雅士 (50403291)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 小野洋輔 (60893211)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 谷村憲司 (80593988)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 太田創 (90459173)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. HIRAIKE Osamu

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. KAWAGUCHI Ryuji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. YONEDA Satoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. HARADA Miyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 斎藤滋

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
18. 大須賀穣

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
19. 奥野利明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 甲賀かをり

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
21. 島友子

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
22. 平岡毅大

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 折坂誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 井上聰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 平田哲也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YOSHINO OSAMU 吉野 修

YOSHINO Osamu 吉野 修

Research Projects

Research Products

Co-Researchers

平滑筋機能に着目した真に着床・妊娠を可能とする再生子宮

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ネオ・セルフ抗体による不妊症、子宮内膜症の病態解明と治療法の確立

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女性ホルモンによる腸内細菌を介した免疫細胞制御機構の解明Principal Investigator

Principal Investigator

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Elucidation and treatment of physiological phenomena and abnormalities of pregnancy based on macrophage balancePrincipal Investigator

Principal Investigator

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Review Section

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The effect of stress on immune system and the progression of endometriosis.Principal Investigator

Principal Investigator

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Development of innovative implantation patch for medical treatments of infertility

Principal Investigator

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the bradykinin system in endometriosisPrincipal Investigator

Principal Investigator

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[Book] HORMONE FRONTIER IN GYNECOLOGY(Vol.23 No.2)2016

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[Journal Article] 着床不全とネオ・セルフ抗体2023

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[Journal Article] Anti-β2-Glycoprotein I/HLA-DR antibody in infertility.2023

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DOI

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[Journal Article] National survey of abnormal uterine bleeding according to the FIGO classification in Japan2022

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DOI

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[Journal Article] Guidelines for Reproductive Medicine in Japan2022

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[Journal Article] Oral Gonadotropin-Releasing Hormone Antagonist Relugolix Has the Same Effect as Gonadotropin-Releasing Hormone Agonist Injections in Terms of Preparation for Transcervical Resection Myomectomy2022

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[Journal Article] Guideline for Gynecological Practice in Japan: Japan Society of Obstetrics and Gynecology and Japan Association of Obstetricians and Gynecologists 2020 edition2021

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YOSHINO OSAMU 吉野修

YOSHINO Osamu 吉野修

[Journal Article] PAI-1 in granulosa cells is suppressed directly by statin and indirectly by suppressing　TGF-β and TNF-α in mononuclear cells by insulin-sensitizing drugs.2017