Tanihata Jun 谷端淳

… Alternative Names

TANIHATA Jun 谷端淳

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Researcher Number	00508426
Other IDs
Affiliation (Current)	2025: 東京慈恵会医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2021 – 2024: 東京慈恵会医科大学, 医学部, 講師 2017 – 2021: 東京慈恵会医科大学, 医学部, 助教 2016: 国立研究開発法人国立精神・神経医療研究センター, 神経研究所遺伝子疾患治療研究部, 流動研究員 2013 – 2014: 独立行政法人国立精神・神経医療研究センター, 神経研究所遺伝子疾患治療研究部, 流動研究員 2011: 独立行政法人国立精神・神経医療研究センター, 神経研究所・遺伝子疾患治療研究部, 流動研究員 2011: 独立行政法人国立精神・神経医療研究センター, 神経研究所遺伝子疾患治療研究部, 流動研究員 2010: 早稲田大学, 人間科学学術院, 助手
Review Section/Research Field	Principal Investigator Basic Section 56020:Orthopedics-related / Experimental pathology / Sports science Except Principal Investigator Basic Section 59040:Nutrition science and health science-related / Basic Section 53030:Respiratory medicine-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Eating habits, studies on eating habits
Keywords	Principal Investigator SERCA / 筋小胞体 / 筋萎縮抑制 / 細胞内Ca2+ / サルコリピン / リアノジン受容体 / 筋ジストロフィー / 細胞内Ca2;濃度 / CDN1163 / 細胞内カルシウム … More / 筋萎縮 / 抗酸化ストレス応答 / 筋小胞体Ca2+ ATPアーゼ / 細胞内Ca2+濃度 / SERCA機能 / ＳＥＲＣＡ / 細胞内Ca2+動態 / ニトロシル化 / ベッカー型筋ジストロフィー / デュシェンヌ型筋ジストロフィー / Duchenne型筋ジストロフィー / 細胞内カルシウム濃度 / nNOS / 短縮型ジストロフィン / 細胞内カルシウム動態 / カルシウム動態 / ｎＮＯＳ / 褐色脂肪組織 / 腎周囲脂肪組織 / 精巣周囲脂肪組織 / グルココルチコイド受容体 / 脱共益型タンパク質 / アドレナリン受容体 / 脂肪分解 / デキサメタゾン / クレンブテロール … More Except Principal Investigator 電子顕微鏡 / 宇宙医学 / 微小重力 / 宇宙環境 / Parkin / COPD / サルコペニア / 閉塞性肺疾患 / 肝臓 / 消化 / 胃 / microRNA / 筋収縮 / 筋肥大 / エクソソーム / ミトコンドリア異常 / ROS産生 / マイトファジー / 創傷治癒 / 瘢痕 / アカハライモリ / Newtic1 / 赤血球 / 筋線維 / 線維化 / 再生 / イモリ / 脱分化 / リプログラミング / 筋電図 / 認知フィードバック / 視覚 / ラテラリティ / 箸操作 / 食関連動作とラテラリティ / 健康と食生活 Less

微小重力下における肝内脂肪滴増大現象の分子メカニズムの解明
- Principal Investigator
  
  暮地本宙己
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Jikei University School of Medicine
Development of a method to inhibit muscle atrophy by targeting direct sarcoplasmic reticulum Ca2+ reuptake mechanism activation by drugs.Principal Investigator
- Principal Investigator
  
  谷端淳
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Jikei University School of Medicine
involvement of microRNA in the pathogenesis of COPD related sarcopenia
- Principal Investigator
  
  Hashimoto Mitsuo
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nippon Sport Science University
  Jikei University School of Medicine
Development of a method to inhibit muscle atrophy by targeting accelerated Ca2+ reuptake into the sarcoplasmic reticulumPrincipal Investigator
- Principal Investigator
  
  Tanihata Jun
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Jikei University School of Medicine
胃の消化が宇宙環境に適応するメカニズムの形態学的解析
- Principal Investigator
  
  暮地本宙己
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Jikei University School of Medicine
Involvement of Parkin-mediated mitophagy in the pathogenesis of chronic obstructive pulmonary disease-related sarcopenia
- Principal Investigator
  
  Hirofumi Utsumi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Jikei University School of Medicine
Elucidating somatic cell reprogramming factors that enable newt-type organ regeneration and extending it to the medical field
- Principal Investigator
  
  Chiba Chikafumi
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  University of Tsukuba
Truncated dystrophin ameliorates the dystrophic phenotype of mdx mice by reducing sarcolipin-mediated SERCA inhibition.Principal Investigator
- Principal Investigator
  
  Tanihata Jun
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Jikei University School of Medicine
  National Center of Neurology and Psychiatry
Functional role of truncated dystrophin with deletion exon 45-55Principal Investigator
- Principal Investigator
  
  TANIHATA Jun
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  National Center of Neurology and Psychiatry
Association between plasticity of adipose tissue and expression of adrenergic receptor and glucocorticoid receptorPrincipal Investigator
- Principal Investigator
  
  TANIHATA Jun
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Sports science
- Research Institution
  独立行政法人国立精神・神経医療研究センター
   Waseda University
The relationship between the laterality of chopstick manipulation and vision-recognition feed-back system in humans : Electromyograph analyses
- Principal Investigator
  
  TACHIYASHIKI Kaoru
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits, studies on eating habits
- Research Institution
  Joetsu University of Education

[Book] 実験医学増刊　超高齢社会に挑む骨格筋のメディカルサイエンス2018
- Author(s)
  谷端　淳・野口　悟（編　武田　伸一）
- Total Pages
  230
- Publisher
  羊土社
- ISBN
  9784758103701
- Data Source
  KAKENHI-PROJECT-16K08726
[Book] CLINICAL CALCIUM　運動器－エネルギー代謝連関－2018
- Author(s)
  谷端　淳・武田　伸一（編　山内　敏正）
- Total Pages
  156
- Publisher
  医薬ジャーナル社
- ISBN
  9784753286331
- Data Source
  KAKENHI-PROJECT-16K08726
[Journal Article] Full-length human dystrophin on human artificial chromosome compensates for mouse dystrophin deficiency in a Duchenne muscular dystrophy mouse model2023
- Author(s)
  Hiramuki Yosuke、Abe Satoshi、Uno Narumi、Kazuki Kanako、Takata Shuta、Miyamoto Hitomaru、Takayama Haruka、Morimoto Kayoko、Takehara Shoko、Osaki Mitsuhiko、Tanihata Jun、Takeda Shin’ichi、Tomizuka Kazuma、Oshimura Mitsuo、Kazuki Yasuhiro
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 4360-4360
- DOI
  10.1038/s41598-023-31481-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K08684, KAKENHI-PROJECT-20K09511
[Journal Article] Urinary titin is not an early biomarker of skeletal muscle atrophy induced by muscle denervation in mice2023
- Author(s)
  Tanihata Jun、Minamisawa Susumu
- Journal Title
  
  PLOS ONE
  
  Volume: 18 Issue: 8 Pages: e0289185-e0289185
- DOI
  10.1371/journal.pone.0289185
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K08684, KAKENHI-PROJECT-20K09511, KAKENHI-PROJECT-21H02884
[Journal Article] Involvement of Parkin‐mediated mitophagy in the pathogenesis of chronic obstructive pulmonary disease‐related sarcopenia2022
- Author(s)
  Ito Akihiko、Hashimoto Mitsuo、Tanihata Jun、 et al.,
- Journal Title
  
  Journal of Cachexia, Sarcopenia and Muscle
  
  Volume: 13 Issue: 3 Pages: 1864-1882
- DOI
  10.1002/jcsm.12988
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09511, KAKENHI-PROJECT-20K08579
[Journal Article] Thiamine treatment preserves cardiac function against ischemia injury via maintaining mitochondrial size and ATP levels2021
- Author(s)
  Yamada Yuki、Kusakari Yoichiro、Akaoka Munetoshi、Watanabe Masato、Tanihata Jun、Nishioka Naritomo、Bochimoto Hiroki、Akaike Toru、Tachibana Toshiaki、Minamisawa Susumu
- Journal Title
  
  Journal of Applied Physiology
  
  Volume: 130 Issue: 1 Pages: 26-35
- DOI
  10.1152/japplphysiol.00578.2020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09511, KAKENHI-PROJECT-20K11539, KAKENHI-PROJECT-17H01529, KAKENHI-PROJECT-21H02884
[Journal Article] Transcriptome analysis of gravitational effects on mouse skeletal muscles under microgravity and artificial 1 g onboard environment2021
- Author(s)
  Risa Okada, 他15名, Naoki Ito, Dai Shiba, Masaki Shirakawa, Masafumi Muratani, Takashi Kudo, Satoru Takahashi.
- Journal Title
  
  Scientific reports
  
  Volume: 11 Issue: 1 Pages: 9168-9168
- DOI
  10.1038/s41598-021-88392-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K19505, KAKENHI-PROJECT-19K24306, KAKENHI-PROJECT-20H03234, KAKENHI-PROJECT-20K09511
[Journal Article] iNOS is not responsible for RyR1 S-nitrosylation in mdx mice with truncated dystrophin2020
- Author(s)
  Nogami Ken’ichiro、Maruyama Yusuke、Elhussieny Ahmed、Sakai-Takemura Fusako、Tanihata Jun、Kira Jun-ichi、Miyagoe-Suzuki Yuko、Takeda Shin’ichi
- Journal Title
  
  BMC Musculoskeletal Disorders
  
  Volume: 21 Issue: 1 Pages: 479-479
- DOI
  10.1186/s12891-020-03501-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09511, KAKENHI-PROJECT-19K07519
[Journal Article] The nSMase2/Smpd3 gene modulates the severity of muscular dystrophy and the emotional stress response in mdx mice2020
- Author(s)
  Matsuzaka Yasunari、Tanihata Jun、Ooshima Yoshiko、Yamada Daisuke、Sekiguchi Masayuki、Miyatake Shouta、Aoki Yoshitsugu、Terumitsu Mika、Yashiro Ryu、Komaki Hirofumi、Ishiyama Akihiko、Oya Yasushi、Inoue Yukiko U.、Inoue Takayoshi、Takeda Shin’ichi、Hashido Kazuo
- Journal Title
  
  BMC Medicine
  
  Volume: 18 Issue: 1 Pages: 343-343
- DOI
  10.1186/s12916-020-01805-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06467, KAKENHI-PROJECT-20K09511, KAKENHI-PROJECT-19K16035
[Journal Article] Glycerophospholipid profile alterations are associated with murine muscle‐wasting phenotype2020
- Author(s)
  Senoo Nanami、Miyoshi Noriyuki、Kobayashi Eri、Morita Akihito、Tanihata Jun、Takeda Shin'ichi、Miura Shinji
- Journal Title
  
  Muscle & Nerve
  
  Volume: 62 Issue: 3 Pages: 413-418
- DOI
  10.1002/mus.26993
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09511, KAKENHI-PROJECT-19K22814
[Journal Article] Troponin T amino acid mutation (ΔK210) knock-in mice as a neonatal dilated cardiomyopathy model2020
- Author(s)
  Tanihata Jun、Fujii Teruyuki、Baba Shunsuke、Fujimoto Yoshitaka、Morimoto Sachio、Minamisawa Susumu
- Journal Title
  
  Pediatric Research
  
  Volume: 89 Issue: 4 Pages: 846-857
- DOI
  10.1038/s41390-020-1016-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09511, KAKENHI-PROJECT-17H01529, KAKENHI-PROJECT-21H02884
[Journal Article] Mutation-independent Proteomic Signatures of Pathological Progression in Murine Models of Duchenne Muscular Dystrophy2020
- Author(s)
  van Westering Tirsa L.E.、Johansson Henrik J.、Hanson Britt、Coenen-Stass Anna M.L.、Lomonosova Yulia、Tanihata Jun、Motohashi Norio、Yokota Toshifumi、Takeda Shin'ichi、Lehti? Janne、Wood Matthew J.A.、EL Andaloussi Samir、Aoki Yoshitsugu、Roberts Thomas C.
- Journal Title
  
  Molecular & Cellular Proteomics
  
  Volume: 19 Issue: 12 Pages: 2047-2068
- DOI
  10.1074/mcp.ra120.002345
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09511, KAKENHI-PROJECT-18K07544, KAKENHI-PROJECT-18K11067
[Journal Article] Age-Dependent Echocardiographic and Pathologic Findings in a Rat Model with Duchenne Muscular Dystrophy Generated by CRISPR/Cas9 Genome Editing2020
- Author(s)
  Sugihara Hidetoshi、Kimura Koichi、Yamanouchi Keitaro、Teramoto Naomi、Okano Tomoko、Daimon Masao、Morita Hiroyuki、Takenaka Katsu、Shiga Takanori、Tanihata Jun、Aoki Yoshitsugu、Inoue-Nagamura Tokiko、Yotsuyanagi Hiroshi、Komuro Issei
- Journal Title
  
  International Heart Journal
  
  Volume: 61 Issue: 6 Pages: 1279-1284
- DOI
  10.1536/ihj.20-372
- NAID
  130007945853
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09511, KAKENHI-PROJECT-17K07092, KAKENHI-PROJECT-20H03161
[Journal Article] Characterization of a novel microRNA, miR-188, elevated in serum of muscular dystrophy dog model.2019
- Author(s)
  Shibasaki H, Imamura M, Arima S, Tanihata J, Kuraoka M, Matsuzaka Y, Uchiumi F, Tanuma SI, Takeda S.
- Journal Title
  
  PLoS One
  
  Volume: 14(1) Issue: 1 Pages: e0211597-e0211597
- DOI
  10.1371/journal.pone.0211597
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02685, KAKENHI-PROJECT-16K08327, KAKENHI-PROJECT-16K08726
[Journal Article] Loss of RNA-binding protein Sfpq causes long-gene transcriptopathy in skeletal muscle and severe muscle mass reduction with metabolic myopathy.2019
- Author(s)
  Hosokawa M, Takeuchi A, Tanihata J, Iida K, Takeda S, Hagiwara M
- Journal Title
  
  iScience
  
  Volume: 13 Pages: 229-242
- DOI
  10.1016/j.isci.2019.02.023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08726, KAKENHI-PROJECT-15H05721
[Journal Article] Urinary titin is increased in patients after cardiac surgery.2019
- Author(s)
  Tanihata J, Nishioka N, Inoue T, Bando K, Minamisawa S
- Journal Title
  
  Front Cardiovasc Med
  
  Volume: 6 Pages: 7-7
- DOI
  10.3389/fcvm.2019.00007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08726, KAKENHI-PROJECT-17H01529
[Journal Article] Synthesis of 2'-O-(N-methylcarbamoylethyl) 5-methyl-2-thiouridine and its application to splice-switching oligonucleotides.2019
- Author(s)
  Masaki Y, Yamamoto K, Inde T, Yoshida K, Maruyama A, Nagata T, Tanihata J, Takeda S, Sekine M, Seio K
- Journal Title
  
  Bioorg Med Chem Lett
  
  Volume: 29 Issue: 2 Pages: 60-163
- DOI
  10.1016/j.bmcl.2018.12.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08726, KAKENHI-PROJECT-17H04886, KAKENHI-PROJECT-16H05221
[Journal Article] Truncated dystrophin ameliorates the dystrophic phenotype of mdx mice by reducing sarcolipin-mediated SERCA inhibition2018
- Author(s)
  Tanihata Jun、Nagata Tetsuya、Ito Naoki、Saito Takashi、Nakamura Akinori、Minamisawa Susumu、Aoki Yoshitsugu、Ruegg Urs T.、Takeda Shin'ichi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 505 Issue: 1 Pages: 51-59
- DOI
  10.1016/j.bbrc.2018.09.039
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01529, KAKENHI-PROJECT-16K08726, KAKENHI-PROJECT-16K15184, KAKENHI-PROJECT-16H05221
[Journal Article] Low intensity training and the C5a complement antagonist NOX-D21 rescue the mdx phenotype through modulation of inflammation.2017
- Author(s)
  Janek Hyzewicz, Jun Tanihata, Mutsuki Kuraoka, Yuko Nitahara-Kasahara, Teiva Beylier, Urs T Ruegg, Axel Vater, Shin’ichi Takeda.
- Journal Title
  
  American Journal of Pathology
  
  Volume: 187 Issue: 5 Pages: 1147-1161
- DOI
  10.1016/j.ajpath.2016.12.019
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860273, KAKENHI-PROJECT-16K08726
[Journal Article] Treatment with the anti-IL-6 receptor antibody attenuates muscular dystrophy via promoting skeletal muscle regeneration in dystrophin-/utrophin-deficient mice2017
- Author(s)
  Wada Eiji、Tanihata Jun、Iwamura Akira、Takeda Shin’ichi、Hayashi Yukiko K.、Matsuda Ryoichi
- Journal Title
  
  Skeletal Muscle
  
  Volume: 7 Issue: 1 Pages: 23-23
- DOI
  10.1186/s13395-017-0140-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08726, KAKENHI-PROJECT-16K18385, KAKENHI-PROJECT-17H06112
[Journal Article] Changes in cytosolic Ca<sup>2+</sup> dynamics in the sarcoplasmic reticulum associated with the pathology of Duchenne muscular dystrophy2016
- Author(s)
  Tanihata J, Takeda S
- Journal Title
  
  The Journal of Physical Fitness and Sports Medicine
  
  Volume: 5 Issue: 4 Pages: 309-312
- DOI
  10.7600/jpfsm.5.309
- NAID
  130005420265
- ISSN
  2186-8123, 2186-8131
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K08726
[Journal Article] Changes in cytosolic Ca2+dynamics associated with muscular dystrophy.2016
- Author(s)
  Jun Tanihata, Shin'ichi Takeda
- Journal Title
  
  Clinical Calcium
  
  Volume: 26 Pages: 1677-1683
- Open Access
- Data Source
  KAKENHI-PROJECT-16K08726
[Journal Article] Enhancement of exon skipping in mdx52 mice by 2′-O-methyl-2-thioribothymidine incorporation into phosphorothioate oligonucleotides.2015
- Author(s)
  Masaki Y, Inde T, Nagata T, Tanihata J, Kanamori T, Seio K, Takeda S, Sekine M
- Journal Title
  
  Med Chem Commun
  
  Volume: 6 Issue: 6 Pages: 630-633
- DOI
  10.1039/c5md00079c
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25860306
[Journal Article] Long-term efficacy of systemic multiexon skipping targeting dystrophin exons 45-55 with a cocktail of vivo-morpholinos in mdx52 mice.2015
- Author(s)
  Echigoya Y, Aoki Y, Miskew B, Panesar D, Touznik A, Nagata T, Tanihata J, Nakamura A, Nagaraju K, Yokota T
- Journal Title
  
  Mol Ther Nucleic Acids
  
  Volume: 4 Pages: e225-e225
- DOI
  10.1038/mtna.2014.76
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25860306, KAKENHI-PROJECT-25460666, KAKENHI-PROJECT-25461303
[Journal Article] Low intensity training of mdx mice reduces carbonylation and increases expression levels of proteins involved in energy metabolism and muscle contraction.2015
- Author(s)
  Hyzewicz J, Tanihata J, Kuraoka M, Ito N, Miyagoe-Suzuki Y, Takeda S
- Journal Title
  
  Free Radic Biol Med
  
  Volume: 82 Pages: 122-136
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25860306
[Journal Article] Nakamura K, Fujii W, Tsuboi M, Tanihata J, Teramoto N, Takeuchi S, Naito K, Yamanouchi K, Nishihara M2014
- Author(s)
  Nakamura K, Fujii W, Tsuboi M, Tanihata J, Teramoto N, Takeuchi S, Naito K, Yamanouchi K, Nishihara M
- Journal Title
  
  Scientific Reports
  
  Volume: 4 Issue: 1 Pages: 5635-5635
- DOI
  10.1038/srep05635
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-12J07714, KAKENHI-PROJECT-23228004, KAKENHI-PROJECT-25252056, KAKENHI-PROJECT-25292185, KAKENHI-PROJECT-25860306, KAKENHI-PROJECT-26712025
[Journal Article] Mutation types and aging differently affect revertant fiber expansion in dystrophic mdx and mdx52 mice.2013
- Author(s)
  Echigoya Y, Lee J, Rodrigues M, Nagata T, Tanihata J, Nozohourmehrabad A, Panesar D, Miskew B, Aoki Y, Yokota T.
- Journal Title
  
  PLoS One
  
  Volume: 8(7) Issue: 7 Pages: e69194-e69194
- DOI
  10.1371/journal.pone.0069194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461303, KAKENHI-PROJECT-25860306
[Patent] 筋細胞損傷抑制剤2014
- Inventor(s)
  橋戸和夫, 松坂恭成, 谷端淳
- Industrial Property Rights Holder
  橋戸和夫, 松坂恭成, 谷端淳
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-226518
- Filing Date
  2014-11-06
- Data Source
  KAKENHI-PROJECT-25860306
[Presentation] 模擬微小重力曝露による筋細胞内Ca2+濃度低下が筋芽細胞増殖に及ぼす影響2024
- Author(s)
  3)市原彩夏，谷端　淳、榎木裕紀，松元一明，南沢　享
- Organizer
  第8回若手による骨格筋細胞研究会
- Data Source
  KAKENHI-PROJECT-20K09511
[Presentation] Sfpq-KO-マウスをモデルとした骨格筋エネルギー代謝-筋量制御連関及び、SFPQによる長鎖遺伝子発現制御機構の解明2024
- Author(s)
  細川元靖、飯田　慶、谷端　淳、武田伸一、萩原正敏、武内章英
- Organizer
  第8回若手による骨格筋細胞研究会
- Data Source
  KAKENHI-PROJECT-23K08684
[Presentation] 微小重力は細胞内カルシウム濃度の低下を介して細胞増殖を抑制する2024
- Author(s)
  市原彩夏，谷端　淳、榎木裕紀，松元一明，南沢　享
- Organizer
  第101回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-23K08684
[Presentation] 微小重力は細胞内カルシウム濃度の低下を介して細胞増殖を抑制する2024
- Author(s)
  市原彩夏，谷端　淳、榎木裕紀，松元一明，南沢　享
- Organizer
  第101回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-20K09511
[Presentation] Sfpq-KO-マウスをモデルとした骨格筋エネルギー代謝-筋量制御連関及び、SFPQによる長鎖遺伝子発現制御機構の解明2024
- Author(s)
  細川元靖、飯田　慶、谷端　淳、武田伸一、萩原正敏、武内章英
- Organizer
  第8回若手による骨格筋細胞研究会
- Data Source
  KAKENHI-PROJECT-20K09511
[Presentation] 模擬微小重力曝露による筋細胞内Ca2+濃度低下が筋芽細胞増殖に及ぼす影響2024
- Author(s)
  市原彩夏，谷端　淳、榎木裕紀，松元一明，南沢　享
- Organizer
  第8回若手による骨格筋細胞研究会
- Data Source
  KAKENHI-PROJECT-23K08684
[Presentation] Relationship between microgravity and myoblast proliferation2023
- Author(s)
  Ichihara A, Tanihata J, Enoki Y, Matsumoto K, Minamisawa S
- Organizer
  The 10th Federation of the Asian and Oceanian Physiological Societies Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K08684
[Presentation] Relationship between microgravity and myoblast proliferation.2023
- Author(s)
  Ichihara A, Tanihata J, Enoki Y, Matsumoto K, Minamisawa S:
- Organizer
  The 10th Federation of the Asian and Oceanian Physiological Societies Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09511
[Presentation] Vitamin B1 pretreatment prevents cardiac mitochondrial morphology from ischemia/reperfusion injury.2019
- Author(s)
  Kusakari Y, Nishioka N, Tanihata J, Minamisawa S
- Organizer
  FAOPS 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08726
[Presentation] Acute Overstretch Causes Abrupt Inner Mitochondrial Collapsing of Rat Papillary Muscle.2019
- Author(s)
  Nishioka N, Kusakari Y, Tanihata J, Minamisawa S
- Organizer
  FAOPS 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08726
[Presentation] Truncated dystrophin ameliorates the dystrophic phenotype by sarcolipin-mediated SERCA inhibition.2019
- Author(s)
  Tanihata J, Nagata T, Ito N, Saito T, Nakamura A, Minamisawa S, Aoki Y, Urs T, Takeda S
- Organizer
  FAOPS 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08726
[Presentation] Urine connectin/titin is increased in patients after heart surgeries with cardiopulmonary bypass.2018
- Author(s)
  Tanihata J, Nishioka N, Inoue T, Bando K, Minamisawa S
- Organizer
  Experimental Biology 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08726
[Presentation] Acute Diastolic Overstretch Causes Abrupt Inner Mitochondrial Collapsing of Isolated Rat Papillary Muscle.2018
- Author(s)
  Nishioka N, Kusakari Y, Tanihata J, Minamisawa S
- Organizer
  AHA Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08726
[Presentation] 筋ジストロフィー犬の血清で見出された新規microRNAの筋分化における解析2018
- Author(s)
  柴崎浩之，今村道博，谷端　淳，有馬さゆり，倉岡睦季，松坂泰成，内海文彰，田沼靖一，武田伸一
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K08726
[Presentation] RNA結合タンパク質Sfpqによる骨格筋における代謝遺伝子発現制御．2018
- Author(s)
  細川元靖，武内章英，谷端　淳，飯田　慶，武田伸一，萩原正敏
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K08726
[Presentation] RNA結合タンパク質Sfpqによる骨格筋における代謝遺伝子発現制御2018
- Author(s)
  細川元靖，武内章英，谷端　淳，飯田　慶，武田伸一，萩原正敏
- Organizer
  日本筋学会第4回学術集会
- Data Source
  KAKENHI-PROJECT-16K08726
[Presentation] DMD病態における細胞内Ca2+動態異常2018
- Author(s)
  谷端　淳，永田哲也，中村昭則，青木吉嗣，Urs Ruegg，南沢　享，武田伸一
- Organizer
  日本筋学会第4回学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08726
[Presentation] 開心術後、尿中タイチンは上昇する．―新たな心筋障害マーカーの可能性―2018
- Author(s)
  西岡成知、南沢　享、谷端　淳、井上天宏、雨谷　優、木南寛造、中尾充貴、篠原　玄、山城理仁、松村洋高、宇野吉雅、儀武路雄、坂東　興、森田紀代造、橋本和弘
- Organizer
  第71回日本胸部外科学会総会
- Data Source
  KAKENHI-PROJECT-16K08726
[Presentation] 心筋傷害検出における尿中タイチン測定の意義-新たなBiomarkerの可能性2018
- Author(s)
  西岡成知、南沢　享、谷端　淳、井上天宏、坂東　興
- Organizer
  JSPPPEC
- Data Source
  KAKENHI-PROJECT-16K08726
[Presentation] ジストロフィン欠損における血清microRNAの解析2017
- Author(s)
  2)柴崎浩之，倉岡睦季，松坂泰成，谷端　淳，内海文彰，田沼靖一，今村道博，武田伸一
- Organizer
  2017年度生命科学系学会合同年次大会（第40回日本分子生物学会年会）
- Data Source
  KAKENHI-PROJECT-16K08726
[Presentation] Sfpq欠損は超長鎖遺伝子の発現を減少させ、重篤な筋成長不全を伴う代謝性ミオパチーを引き起こした.2017
- Author(s)
  3)細川元靖，武内章英，谷端　淳，飯田　慶，武田伸一，萩原正敏
- Organizer
  第93回日本解剖学会近畿支部学術集会
- Data Source
  KAKENHI-PROJECT-16K08726
[Presentation] Cytosolic Ca2+ dynamics through the SR is associated with pathology of muscular dystrophy.2017
- Author(s)
  6)Tanihata J, Nagata T, Ito N, Saito T, Nakamura A, Minamisawa S, Aoki Y, Takeda S
- Organizer
  第3回Neo Vitamin D Workshop学術集会
- Data Source
  KAKENHI-PROJECT-16K08726
[Presentation] Cytosolic Ca2+ Dynamics Through the SR is Associated with Pathology of Muscular Dystrophy.2017
- Author(s)
  2)Tanihata J, Nagata T, Ito N, Saito T, Nakamura A, Minamisawa S, Aoki Y, Takeda S
- Organizer
  20th International Symposium on Calcium Binding Proteins and Calcium Function in Health and Disease (CaBP20)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08726
[Presentation] Functional analysis of MyoD-transduced fibroblasts and urine-derived cells from healthy individual and patients with Duchenne muscular dystrophy.2017
- Author(s)
  4)Takizawa H, Hara Y, Miyatake S, Tanihata J, Mizobe Y, Saito T, Takeda S, Aoki Y:
- Organizer
  XXII World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08726
[Presentation] 筋ジストロフィー病態における細胞内Ca2+動態の解明と新たな治療法の開発2017
- Author(s)
  7)谷端　淳，永田哲也，伊藤尚基，齊藤　崇，中村昭則，南沢　享，青木吉嗣，武田伸一
- Organizer
  日本筋学会第3回学術集会
- Data Source
  KAKENHI-PROJECT-16K08726
[Presentation] Sarcolipin deletion ameliorates the dystrophic phenotype of2016
- Author(s)
  谷端　淳, 永田　哲也, 伊藤　尚基, 齋藤　崇, 中村　昭則, 南沢享,　青木　吉嗣,　武田　伸一
- Organizer
  第2回日本筋学会
- Place of Presentation
  東京
- Year and Date
  2016-08-05
- Data Source
  KAKENHI-PROJECT-16K08726
[Presentation] 筋ジストロフィー病態における細胞内Ca2+動態の解明と新たな治療法の開発2016
- Author(s)
  谷端　淳、永田哲也、伊藤尚基、斎藤　崇、青木吉嗣、武田伸一
- Organizer
  第71回日本体力医学会
- Place of Presentation
  盛岡
- Year and Date
  2016-09-23
- Data Source
  KAKENHI-PROJECT-16K08726
[Presentation] Cytosolic Ca2+ dynamics through the SR is associated with pathology of muscular dystrophy2016
- Author(s)
  Jun Tanihata, Tetsuya Nagata, Ito Naoki, Takashi Saito, Akinori Nakamura, Yoshitsugu Aoki, Shin’ichi Takeda
- Organizer
  Society for muscle biology
- Place of Presentation
  カリフォルニア
- Year and Date
  2016-06-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08726
[Presentation] Truncated dystrophin with exon 45-55 deletion induced muscle atrophy and fiber type change through the hyper-nitrosylation of the ryanodine receptor type-1 and constant release of Ca2+ to the cytosol2014
- Author(s)
  Jun Tanihata, Tetsuya Nagata, Takashi Saito, Naoki Ito, Yoshitsugu Aoki, Akinori Nakamura, Shin’ichi Takeda
- Organizer
  19th International WMS Congress
- Place of Presentation
  Langenbeck-Virchow-Haus, Ｂｅｒｌｉｎ，　Ｇｅｒｍａｎｙ
- Data Source
  KAKENHI-PROJECT-25860306
[Presentation] 患者由来細胞を用いたデュシェンヌ型筋ジストロフィーに対するエクソン・スキッピング治療の開発2011
- Author(s)
  斉藤崇、永田哲也、青木吉嗣、谷端淳、増田智、本橋裕子、横田俊文、武田伸一
- Organizer
  第32回日本臨床薬理学会年回シンポジウム2「ヒト組織を用いた臨床薬理学研究の発展」
- Place of Presentation
  浜松
- Year and Date
  2011-12-01
- Data Source
  KAKENHI-PROJECT-22700664
[Presentation] モルフォリノを用いたエクソン45-55ブロックスキップによりDuchenne型筋ジストロフィーマウスの筋病理と筋機能は改善する2011
- Author(s)
  青木吉嗣、横田俊文、永田哲也、谷端淳、斉藤崇、中村昭則、Eric Hoffman、Terence Partridge、武田伸一
- Organizer
  第6回筋ジストロフィー治療研究合同発表会
- Place of Presentation
  熊本
- Year and Date
  2011-11-05
- Data Source
  KAKENHI-PROJECT-22700664
[Presentation] Effects of dexamethasone on the expression of beta adrenoceptors and glucocorticoid receptor mRNAs in white and brown adipose tissues of rats2010
- Author(s)
  谷端淳、佐藤章悟、立屋敷かおる、今泉和彦
- Organizer
  日本生理学会
- Place of Presentation
  盛岡
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-22700664
[Presentation] Generation of Dystrophin mutated rats with a CRISPR/Cas system as a new animal model of muscular dystrophy.
- Author(s)
  Katsuyuki Nakamura, Wataru Fujii, Masaya Tsuboi, Jun Tanihata, Naomi Teramoto, Shiho Takeuchi, Kunihiko Naito, Keitaro Yamanouchi, Masugi Nishihara
- Organizer
  2014 FASEB Science Research Conferences（Skeletal Muscle Satellite and Stem Cells）
- Place of Presentation
  Steamboat Springs, Colorado, USA
- Year and Date
  2014-07-20 – 2014-07-25
- Data Source
  KAKENHI-PROJECT-25860306
[Presentation] Exon45-55を欠失した短縮型dystrophinはRyR1をニトロシル化し、細胞内Ca2＋濃度を上昇させる．
- Author(s)
  谷端　淳，永田哲也，齊藤　崇，伊藤尚基，中村昭則，武田伸一
- Organizer
  第69回日本体力医学会大会
- Place of Presentation
  長崎・長崎大学
- Year and Date
  2014-09-19 – 2014-09-21
- Data Source
  KAKENHI-PROJECT-25860306
[Presentation] Truncated dystrophin with exon 45-55 deletion induced muscle atrophy and fiber type change through the hyper-nitrosylation of the ryanodine receptor type-1 and constant release of Ca2+ to the cytosol.
- Author(s)
  Tanihata J, Nagata T, Saito T, Ito N, Aoki Y, Nakamura A, Takeda S
- Organizer
  19th International Congress of the World Muscle Society
- Place of Presentation
  Academic center of Berlin, Berlin, Germany
- Year and Date
  2014-10-07 – 2014-10-11
- Data Source
  KAKENHI-PROJECT-25860306
[Presentation] CRISPR/Cas法を用いた筋ジストロフィーモデルラットの作出
- Author(s)
  中村克行，藤井渉，坪井誠也，谷端　淳，寺本奈保美，竹内志帆，内藤邦彦，山内啓太郎，西原真杉
- Organizer
  第157回日本獣医学会学術集会
- Place of Presentation
  札幌・北海道大学
- Year and Date
  2014-09-09 – 2014-09-12
- Data Source
  KAKENHI-PROJECT-25860306
[Presentation] Low intensity endurance training restores the expression of troponin T and myosin binding protein C Fast type isoforms in gastrocnemius of mdx mice.
- Author(s)
  Janek Hyzewicz，谷端　淳，倉岡睦季，伊藤尚基，鈴木友子，武田伸一
- Organizer
  第35回日本炎症・再生医学会
- Place of Presentation
  沖縄・万国津梁館
- Year and Date
  2014-07-01 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-25860306
[Presentation] Exon45-55を欠失した短縮型dystrophinの機能的役割の解明
- Author(s)
  谷端　淳、永田哲也、齋藤　崇、青木吉嗣、中村昭則、武田伸一
- Organizer
  第68回日本体力医学会
- Place of Presentation
  日本教育会館
- Data Source
  KAKENHI-PROJECT-25860306
[Presentation] Proteomic analysis shows that low intensity training reduces the carbonylation level and increases the expression of energy metabolism and muscle contraction proteins in mdx skeletal muscle.
- Author(s)
  Hyzewicz J, Tanihata J, Kuraoka M, Ito N, Miyagoe-Suzuki Y, Takeda S
- Organizer
  43th European Muscle Conference
- Place of Presentation
  University of Salzburg, Salzburg, Austria
- Year and Date
  2014-09-10 – 2014-09-14
- Data Source
  KAKENHI-PROJECT-25860306

1. 暮地本宙己 (60632841)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
2. Hashimoto Mitsuo (00771742)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 荒屋潤 (90468679)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 南沢享 (40257332)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
5. TACHIYASHIKI Kaoru (20119324)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. IMAIZUMI Kazuhiko (60145068)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. Chiba Chikafumi (80272152)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Hirofumi Utsumi (00773855)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 武田伸一 (90171644)

# of Collaborated Projects: 1 results

# of Collaborated Products: 20 results
10. 青木吉嗣 (80534172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
11. 貴志和生 (40224919)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 田谷雄二 (30197587)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 成島三長 (80431873)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 佐藤貴彦 (30570775)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 加治優一 (50361332)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 外山史 (60323317)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 韓圭鎬 (50553450)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 草刈洋一郎 (80338889)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 立花利公 (80163476)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. INOUE Yukiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. KASAHARA Yuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 田沼靖一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 永田哲也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 伊藤尚基

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tanihata Jun 谷端 淳

TANIHATA Jun 谷端 淳

Research Projects

Research Products

Co-Researchers

微小重力下における肝内脂肪滴増大現象の分子メカニズムの解明

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Development of a method to inhibit muscle atrophy by targeting direct sarcoplasmic reticulum Ca2+ reuptake mechanism activation by drugs.Principal Investigator

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involvement of microRNA in the pathogenesis of COPD related sarcopenia

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Development of a method to inhibit muscle atrophy by targeting accelerated Ca2+ reuptake into the sarcoplasmic reticulumPrincipal Investigator

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胃の消化が宇宙環境に適応するメカニズムの形態学的解析

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Involvement of Parkin-mediated mitophagy in the pathogenesis of chronic obstructive pulmonary disease-related sarcopenia

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Elucidating somatic cell reprogramming factors that enable newt-type organ regeneration and extending it to the medical field

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Truncated dystrophin ameliorates the dystrophic phenotype of mdx mice by reducing sarcolipin-mediated SERCA inhibition.Principal Investigator

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Functional role of truncated dystrophin with deletion exon 45-55Principal Investigator

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Association between plasticity of adipose tissue and expression of adrenergic receptor and glucocorticoid receptorPrincipal Investigator

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The relationship between the laterality of chopstick manipulation and vision-recognition feed-back system in humans : Electromyograph analyses

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[Book] 実験医学 増刊 超高齢社会に挑む骨格筋のメディカルサイエンス2018

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[Book] CLINICAL CALCIUM 運動器－エネルギー代謝連関－2018

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Total Pages

Tanihata Jun 谷端淳

TANIHATA Jun 谷端淳

[Book] 実験医学増刊　超高齢社会に挑む骨格筋のメディカルサイエンス2018

[Book] CLINICAL CALCIUM　運動器－エネルギー代謝連関－2018