Nozaki Masahiro 野崎正浩

… Alternative Names

野崎正浩ノザキマサヒロ

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Researcher Number	00509309
Other IDs
Affiliation (Current)	2025: 名古屋市立大学, 医薬学総合研究院(医学), 准教授
Affiliation (based on the past Project Information) *help	2023: 名古屋市立大学, 医薬学総合研究院(医学), 准教授 2019 – 2022: 名古屋市立大学, 医薬学総合研究院(医学), 講師 2017 – 2018: 名古屋市立大学, 大学院医学研究科, 助教
Review Section/Research Field	Except Principal Investigator Basic Section 56020:Orthopedics-related / Orthopaedic surgery
Keywords	Except Principal Investigator グリオスタチン / 滑膜細胞 / 関節リウマチ / interferon gamma / janus kinase / synoviocytes / rheumatoid arthritis / thymidine phosphorylase / gliostatin / インターフェロン　ガンマ … More / STAT / 滑膜 / チミジンホスホリラーゼ / ヒアルロン酸 / チミジンホシホリラーゼ Less

Developing novel rheumatoid arthritis treatments through gliostatin regulation targeting transcription factors
- Principal Investigator
  
  Nagaya Yuko
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Nagoya City University
Hyaluronate modulates gliostatin expression in rheumatoid fibroblast-like synoviocytes
- Principal Investigator
  
  Nagaya Yuko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagoya City University

All 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] The Janus kinase inhibitor (baricitinib) suppresses the rheumatoid arthritis active marker gliostatin/thymidine phosphorylase in human fibroblast-like synoviocytes2022
- Author(s)
  Joyo Yuji、Kawaguchi Yohei、Yonezu Hiroki、Senda Hiroya、Yasuma Sanshiro、Shiraga Hiroo、Nozaki Masahiro、Aoyama Mineyoshi、Asai Kiyofumi、Murakami Hideki、Waguri-Nagaya Yuko
- Journal Title
  
  Immunologic Research
  
  Volume: 70 Issue: 2 Pages: 208-215
- DOI
  10.1007/s12026-022-09261-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08211, KAKENHI-PROJECT-20K09465, KAKENHI-PROJECT-19K18473
[Journal Article] N-acetyl-seryl-aspartyl-lysyl-proline: A new potential serum biomarker of rheumatoid arthritis2021
- Author(s)
  Oguri, Y, Kawaguchi Y, Tatematsu N, Joyo Y, Mizuguchi K, Yonezu H, Okamoto H, Nozaki M, Kobayashi M, Kuroyanagi G, Aiba H, Asai K, Inoue K, Murakami H, Waguri-Nagaya Y
- Journal Title
  
  Medical Mass Spectrometry
  
  Volume: 5 Pages: 1-10
- NAID
  130008062713
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09465
[Journal Article] Anterolateral ligament reconstruction in addition to primary double-bundle anterior cruciate ligament reconstruction for grade 3 pivot shift improves residual knee instability during surgery2021
- Author(s)
  Kawanishi Yusuke、Kobayashi Makoto、Yasuma Sanshiro、Fukushima Hiroaki、Kato Jiro、Murase Atsunori、Takenaga Tetsuya、Yoshida Masahito、Kuroyanagi Gen、Kawaguchi Yohei、Nagaya Yuko、Murakami Hideki、Nozaki Masahiro
- Journal Title
  
  Journal of Experimental Orthopaedics
  
  Volume: 8 Issue: 1 Pages: 51-51
- DOI
  10.1186/s40634-021-00369-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09465, KAKENHI-PROJECT-19K18471
[Journal Article] Diagnosis of medial meniscal ramp lesion is difficult by pre-operative magnetic resonance imaging evaluation and needs a methodical arthroscopic exploration2021
- Author(s)
  Yasuma Sanshiro、Kobayashi Makoto、Kawanishi Yusuke、Fukushima Hiroaki、Kato Jiro、Takenaga Tetsuya、Yoshida Masahito、Kuroyanagi Gen、kawaguchi Yohei、Nagaya Yuko、Murakami Hideki、Nozaki Masahiro
- Journal Title
  
  Journal of Orthopaedic Science
  
  Volume: - Issue: 6 Pages: 1271-1277
- DOI
  10.1016/j.jos.2021.07.020
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09465, KAKENHI-PROJECT-19K18471
[Journal Article] An Analysis of the Femoral Drilling Angle to Avoid Tunnel Collision during Double-Bundle Anterior Cruciate Ligament and Anterolateral Ligament Reconstruction on the Knee2021
- Author(s)
  Kawanishi Yusuke、Kobayashi Makoto、Yasuma Sanshiro、Fukushima Hiroaki、Kato Jiro、Murase Atsunori、Takenaga Tetsuya、Yoshida Masahito、Kuroyanagi Gen、Kawaguchi Yohei、Nagaya Yuko、Murakami Hideki、Nozaki Masahiro
- Journal Title
  
  The Journal of Knee Surgery
  
  Volume: - Issue: 05 Pages: 0-0
- DOI
  10.1055/s-0041-1736196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09465, KAKENHI-PROJECT-19K18471
[Journal Article] Pyogenic tenosynovitis of the wrist due to Corynebacterium striatum in a patient with dermatomyositis. A case report.2020
- Author(s)
  Kawaguchi Y, Okamoto H, Endo K, Iwata H, Joyo Y, Nozaki, M, Tamechika S, Waguri-Nagaya Y, Murakami H.
- Journal Title
  
  Medicine
  
  Volume: 99 Issue: 3 Pages: e18761-e18761
- DOI
  10.1097/md.0000000000018761
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09114, KAKENHI-PROJECT-17K11020, KAKENHI-PROJECT-20K09465
[Journal Article] Preoperative Knee Instability Affects Residual Instability as Evaluated by Quantitative Pivot-Shift Measurements During Double-Bundle ACL Reconstruction2020
- Author(s)
  Kawanishi Yusuke、Nozaki Masahiro、Kobayashi Makoto、Yasuma Sanshiro、Fukushima Hiroaki、Murase Atsunori、Takenaga Tetsuya、Yoshida Masahito、Kuroyanagi Gen、Kawaguchi Yohei、Nagaya Yuko、Murakami Hideki
- Journal Title
  
  Orthopaedic Journal of Sports Medicine
  
  Volume: 8 Issue: 10 Pages: 1-7
- DOI
  10.1177/2325967120959020
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09465, KAKENHI-PROJECT-19K18471
[Journal Article] Anterolateral ligament reconstruction as an augmented procedure for double-bundle anterior cruciate ligament reconstruction restores rotational stability: Quantitative evaluation of the pivot shift test using an inertial sensor.2020
- Author(s)
  Yasuma S, Nozaki M, Murase A, Kobayashi M, Kawanishi Y, Fukushima H, Takenaga T, Yoshida M, Kuroyanagi G, Kawaguchi Y, Nagaya Y, Murakami H.
- Journal Title
  
  Knee
  
  Volume: S0968-0160 Issue: 2 Pages: 30053-3
- DOI
  10.1016/j.knee.2020.02.015
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09114, KAKENHI-PROJECT-19K18471, KAKENHI-PROJECT-20K09465
[Journal Article] Treatment of simple bone cysts using endoscopic curettage: a case series analysis2018
- Author(s)
  Aiba H, Kobayashi M, Waguri-Nagaya Y, Goto H, Mizutani J, Yamada S, Okamoto H, Nozaki M, Mitsui H, Miwa S, Kobayashi M, Endo K, Saito S, Goto T, Otsuka T.
- Journal Title
  
  J Orthop Surg Res
  
  Volume: 13 Issue: 1 Pages: 168-168
- DOI
  10.1186/s13018-018-0869-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11020, KAKENHI-PROJECT-18K09114, KAKENHI-PROJECT-16K10913
[Journal Article] The Janus kinase inhibitor tofacitinib inhibits TNF-α-induced gliostatin expression in rheumatoid fibroblast-like synoviocytes2018
- Author(s)
  Kawaguchi Y, Waguri-Nagaya Y, Tatematsu N, Oguri Y, Kobayashi M, Nozaki M, Asai K, Aoyama M, Otsuka T
- Journal Title
  
  Clin Exp Rheumatol
  
  Volume: 36 Pages: 559-567
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11020
[Journal Article] Mithramycin has inhibitory effects on gliostatin and matrix metalloproteinase expression induced by gliostatin in rheumatoid fibroblast-like synoviocytes.2018
- Author(s)
  Tatematsu N, Waguri-Nagaya Y, Kawaguchi Y, Oguri Y, Ikuta K, Kobayashi M, Nozaki M, Asai K, Aoyama M, Otsuka T.
- Journal Title
  
  Mod Rheumatol.
  
  Volume: 28(3) Issue: 3 Pages: 495-505
- DOI
  10.1080/14397595.2017.1350332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10101, KAKENHI-PROJECT-16K10913, KAKENHI-PROJECT-17K11020, KAKENHI-PROJECT-18K09114
[Journal Article] The janus kinase inhibitor tofacitinib inhibits TNFα-induced gliostatin expression in rheumatoid fibroblast-like synoviocytes.2018
- Author(s)
  Kawaguchi Y, Waguri-Nagaya Y, Tatematsu N, Oguri Y, Kobayashi M, Nozaki M, Asai K, Aoyama M, Otsuka T.
- Journal Title
  
  Clin Exp Rheumatol
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11020
[Journal Article] Treatment of aneurysmal bone cysts using endoscopic curettage2018
- Author(s)
  Aiba H, Kobayashi M, Waguri-Nagaya Y, Goto H, Mizutani J, Yamada S, Okamoto H, Nozaki M, Mitsui H, Miwa S, Kobayashi M, Endo K, Saito S, Goto T, Otsuka T.
- Journal Title
  
  BMC Musculoskelet Disord
  
  Volume: 19 Issue: 1 Pages: 268-268
- DOI
  10.1186/s12891-018-2176-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11020, KAKENHI-PROJECT-18K09114, KAKENHI-PROJECT-16K10913
[Journal Article] Comparison of quantitative evaluation between cutaneous and transosseous inertial sensors in anterior cruciate ligament deficient knee: A cadaveric study.2017
- Author(s)
  Murase A, Nozaki M, Kobayashi M, Goto H, Yasuma S, Takenaga T, Nagaya Y, Mizutani J, Okamoto H, Iguchi H, Otsuka T.
- Journal Title
  
  J Orthop Sci
  
  Volume: 22 Issue: 5 Pages: 874-879
- DOI
  10.1016/j.jos.2017.04.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10913, KAKENHI-PROJECT-17K11020
[Journal Article] Septic spondylodiscitis due to non-typhoidal Salmonella in a patient with rheumatoid arthritis treated with a TNF inhibitor and methotrexate.2017
- Author(s)
  Kawaguchi Y, Waguri-Nagaya Y, Oguri Y, Nozaki M, Kobayashi M, Otsuka T.
- Journal Title
  
  Modern Rheumatology Case Reports
  
  Volume: － Issue: 2 Pages: 125-129
- DOI
  10.1080/24725625.2017.1417673
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10913, KAKENHI-PROJECT-17K11020
[Presentation] The JAK inhibitor (baricitinib) inhibits IFNγ-induced gliostatin expression in human fibroblast-like synoviocytes.2023
- Author(s)
  Joyo Y, Kawaguchi Y, Yonezu H, Yasuma S, Shiraga H, Nozaki M, Aoyama M, Murakami H, Waguri-Nagaya Y.
- Organizer
  43th SICOT Orthopaedic World Congress 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09465
[Presentation] リウマチ滑膜細胞においてバリシチニブはSTAT1のリン酸化阻害でGLS産生を抑制する.2020
- Author(s)
  上用祐士, 川口洋平, 黒柳元, 小林真, 野崎正浩, 浅井清文, 永谷祐子, 村上英樹.
- Organizer
  第35回日本整形外科学学会基礎学術集会.
- Data Source
  KAKENHI-PROJECT-20K09465
[Presentation] The JAK inhibitor (baricitinib) inhibits IFNγ-induced gliostatin expression in human fibroblast-like synoviocytes.2019
- Author(s)
  Joyo Y, Kawaguchi Y, Oguri Y, Nozaki M, Asai K, Waguri-Nagaya Y.
- Organizer
  Annual European Congress of Rheumatology EULAR 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11020
[Presentation] 生物学的製剤導入時の胸部CT検査で悪性腫瘍が発見された関節リウマチの3例2019
- Author(s)
  上用祐士, 川口洋平, 小林真, 三井裕人, 黒柳元, 野崎正浩, 村上英樹, 永谷祐子.
- Organizer
  第31回中部リウマチ学会
- Data Source
  KAKENHI-PROJECT-17K11020
[Presentation] Ramp lesionの鏡視所見と術前MRI評価との比較.2019
- Author(s)
  安間三四郎, 野崎正浩，小林真, 川西佑典, 永谷祐子，吉田雅人, 三井裕人，黒柳元, 井口普敬.
- Organizer
  第92回日本整形外科学会学術集会
- Data Source
  KAKENHI-PROJECT-17K11020
[Presentation] 高齢関節リウマチ患者の「健康とくらしの調査」2019
- Author(s)
  小嶋雅代, 永谷祐子, 高橋伸典, 祖父江康司, 西梅剛, 鈴木望人, 野崎正浩, 三井裕人, 川口洋平, 黒柳元, 小嶋俊久.
- Organizer
  第34回日本臨床リウマチ学会
- Data Source
  KAKENHI-PROJECT-17K11020
[Presentation] Inertial sensorを用いたpivot shift test の定量評価.ACL再建術前、time zero, 抜釘時の比較-2019
- Author(s)
  安間三四郎, 野崎正浩，小林真, 川西佑典, 永谷祐子，吉田雅人, 三井裕人，黒柳元, 井口普敬.
- Organizer
  第92回日本整形外科学会学術集会
- Data Source
  KAKENHI-PROJECT-17K11020
[Presentation] Novel anti-angiogenic effects of tofacitinib in fibroblast-like synoviocytes derived from patients with RA.2019
- Author(s)
  Kawaguchi Y, Oguri Y, Nozaki M, Asai K, Waguri-Nagaya Y.
- Organizer
  Annual European Congress of Rheumatology EULAR 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11020
[Presentation] 皮膚筋炎に合併した肘部難治性皮膚潰瘍に洗浄液周期的自動注入機能付き陰圧創傷治療システムが有効であった1例2019
- Author(s)
  川口洋平, 永谷祐子, 上用祐士, 小林真, 三井裕人, 黒柳元, 野崎正浩, 村上英樹.
- Organizer
  第31回中部リウマチ学会
- Data Source
  KAKENHI-PROJECT-17K11020
[Presentation] ACL 損傷においてramp lesion が膝不安定性にもたらす影響　- Inertial sensorによるpivot shift test の定量評価-2019
- Author(s)
  野崎正浩，小林真, 安間三四郎, 川西佑典, 永谷祐子，吉田雅人, 三井裕人，黒柳元, 井口普敬.
- Organizer
  第92回日本整形外科学会学術集会
- Data Source
  KAKENHI-PROJECT-17K11020
[Presentation] Circulating gliostatin correlates with serological feature and response to IL-6 inhibitor therapy in patients with RA.2018
- Author(s)
  Oguri Y, Kawaguchi Y, Nozaki M, Asai K, Waguri-Nagaya Y
- Organizer
  39th SICOT Orthopaedic World Congress 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11020
[Presentation] Serum GLS levels were significantly decreased in patients with RA who were treated with tofacitinib.2018
- Author(s)
  Kawaguchi Y, Oguri Y, Nozaki M, Asai K, Waguri-Nagaya Y
- Organizer
  39th SICOT Orthopaedic World Congress 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11020
[Presentation] The inhibitory effects of tacrolimus on gliostatin production in RA synoviocytes.2017
- Author(s)
  Ikuta K, Waguri-Nagaya Y, Kawaguchi Y , Tatematsu N, Kobayashi M, Goto H, Nozaki M, Aoyama M, Asai K, Otsuka T.
- Organizer
  Annual European Congress of Rheumatology (EULAR2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11020
[Presentation] Quantitative Evaluation of the Biomechanical Function of the Anterolateral structure using an inertial sensor2017
- Author(s)
  Sanshiro Yasuma, Masahiro Nozaki, Atsunori Murase, Masaaki Kobayashi, Hideyuki Goto, Yuko Nagaya, , Hirotaka Iguchi, Takanobu Otsuka,
- Organizer
  Orthopedic Research Society Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11020

1. Nagaya Yuko (90291583)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 浅井清文 (70212462)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
3. 川口洋平 (90766734)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
4. KOBA Masaaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. KAKITA Hiroki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 和栗祐子

# of Collaborated Projects: 0 results

# of Collaborated Products: 27 results
7. 青山峰芳

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 黒柳元

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nozaki Masahiro 野崎 正浩

野崎 正浩 ノザキ マサヒロ

Research Projects

Research Products

Co-Researchers

Developing novel rheumatoid arthritis treatments through gliostatin regulation targeting transcription factors

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Hyaluronate modulates gliostatin expression in rheumatoid fibroblast-like synoviocytes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The Janus kinase inhibitor (baricitinib) suppresses the rheumatoid arthritis active marker gliostatin/thymidine phosphorylase in human fibroblast-like synoviocytes2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] N-acetyl-seryl-aspartyl-lysyl-proline: A new potential serum biomarker of rheumatoid arthritis2021

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Anterolateral ligament reconstruction in addition to primary double-bundle anterior cruciate ligament reconstruction for grade 3 pivot shift improves residual knee instability during surgery2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Diagnosis of medial meniscal ramp lesion is difficult by pre-operative magnetic resonance imaging evaluation and needs a methodical arthroscopic exploration2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An Analysis of the Femoral Drilling Angle to Avoid Tunnel Collision during Double-Bundle Anterior Cruciate Ligament and Anterolateral Ligament Reconstruction on the Knee2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pyogenic tenosynovitis of the wrist due to Corynebacterium striatum in a patient with dermatomyositis. A case report.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Preoperative Knee Instability Affects Residual Instability as Evaluated by Quantitative Pivot-Shift Measurements During Double-Bundle ACL Reconstruction2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Anterolateral ligament reconstruction as an augmented procedure for double-bundle anterior cruciate ligament reconstruction restores rotational stability: Quantitative evaluation of the pivot shift test using an inertial sensor.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Treatment of simple bone cysts using endoscopic curettage: a case series analysis2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Janus kinase inhibitor tofacitinib inhibits TNF-α-induced gliostatin expression in rheumatoid fibroblast-like synoviocytes2018

Author(s)

Journal Title

Data Source

[Journal Article] Mithramycin has inhibitory effects on gliostatin and matrix metalloproteinase expression induced by gliostatin in rheumatoid fibroblast-like synoviocytes.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The janus kinase inhibitor tofacitinib inhibits TNFα-induced gliostatin expression in rheumatoid fibroblast-like synoviocytes.2018

Author(s)

Journal Title

Data Source

[Journal Article] Treatment of aneurysmal bone cysts using endoscopic curettage2018

Author(s)

Journal Title

DOI

Data Source

Nozaki Masahiro 野崎正浩

野崎正浩ノザキマサヒロ

[Presentation] ACL 損傷においてramp lesion が膝不安定性にもたらす影響　- Inertial sensorによるpivot shift test の定量評価-2019