Ohta Akihito 太田哲人

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太田哲人オオタアキヒト

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Researcher Number	00510356
Affiliation (based on the past Project Information) *help	2015: 東京医科歯科大学, 医歯(薬)学総合研究科, 非常勤講師 2014: 東京医科歯科大学, 医歯学総合研究科, 非常勤講師 2013: 東京医科歯科大学, 医歯(薬)学総合研究科, 助教 2011: Tokyo Medical and Dental University, 医歯(薬)学総合研究科, 助教 2010: 東京医科歯科大学, 大学院・医歯学総合研究科, 助教 2009: Tokyo Medical and Dental University, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Kidney internal medicine
Keywords	Principal Investigator 遺伝子改変マウス / WNKキナーゼ / ユビキチン / PHAII / 質量分析 / バゾプレシン / インスリン / NaCl共輸送体（NCC） / NaCl共輸送体(NCC) / リン酸化 … More / Akt / ノックインマウス / ユビキチン化 / 偽性低アルドステロン症II型 / 遺伝性高血圧 / アンギオテンシンII / WNK4キナーゼ / アルドステロン / アンギオランシンII / Na-Cl輸送体(NCC) / 高血圧 Less

Analysis of the role of KLHL3/Cullin3 in PHAIIPrincipal Investigator
- Principal Investigator
  
  Ohta Akihito
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tokyo Medical and Dental University
WNK4キナーゼの腎臓における役割の解析Principal Investigator
- Principal Investigator
  
  太田哲人
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tokyo Medical and Dental University

All 2015 2013 2010 2009

All Journal Article Presentation Book

[Book] 偽性低アルドステロン症II型の分子メカニズム医学のあゆみ2010
- Author(s)
  太田哲人、内田信一
- Total Pages
  2
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-21790799
[Journal Article] Generation and analysis of knock-in mice carrying pseudohypoaldosteronism type II-causing mutations in the cullin 3 gene.2015
- Author(s)
  Araki Y, Rai T, Sohara E, Mori T, Inoue Y, Isobe K, Kikuchi E, Ohta A, Sasaki S, Uchida S.
- Journal Title
  
  Biol Open
  
  Volume: 4 Issue: 11 Pages: 1509-1517
- DOI
  10.1242/bio.013276
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15327, KAKENHI-PROJECT-15K19446, KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-25461243, KAKENHI-PROJECT-26670428
[Journal Article] Impaired degradation of WNK by Akt and PKA phosphorylation of KLHL3.2015
- Author(s)
  Yoshizaki Y, Mori Y, Tsuzaki Y, Mori T, Nomura N, Wakabayashi M, Takahashi D, Zeniya M, Kikuchi E, Araki Y, Ando F, Isobe K, Nishida H, Ohta A, Susa K, Inoue Y, Chiga M, Rai T, Sasaki S, Uchida S, Sohara E.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 467 Issue: 2 Pages: 229-234
- DOI
  10.1016/j.bbrc.2015.09.184
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15327, KAKENHI-PROJECT-15K19446, KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-25461243, KAKENHI-PROJECT-26670428, KAKENHI-PROJECT-15K19445, KAKENHI-PROJECT-26860628, KAKENHI-PROJECT-26860629
[Journal Article] Regulation of WNK1 kinase by extracellular potassium.2010
- Author(s)
  Naito S, Ohta A, et al.
- Journal Title
  
  Clin Exp Nephrol.
  
  Volume: (Epub)
- NAID
  10029005115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790799
[Journal Article] Targeted disruption of the Wnk4 gene decreases phosphorylation of Na-Cl cotransporter, increases Na excretion and lowers blood pressure2009
- Author(s)
  Ohta A
- Journal Title
  
  Hum Mol Genet. 18
  
  Pages: 3978-3986
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790799
[Presentation] Acidic motif in WNKs are crucial components for the binding to KLHL32013
- Author(s)
  Akihito Ohta, Shinichi Uchida,　Sei　Sasaki, Dario R. Alessi
- Organizer
  American society of Nephrology annual meeting
- Place of Presentation
  アトランタ、GA、USA
- Data Source
  KAKENHI-PROJECT-25461243
[Presentation] Targeted disruption of the Wnk4 gene decreases phosphorylation of Na-Cl cotransporter, increases Na excretion and lowers blood pressure.(poster session), Kyoto Japan, July, 20092009
- Author(s)
  Ohta A
- Organizer
  The 36th International Congress of Physiological Sciences(第36回国際生理学会)
- Place of Presentation
  京都、日本
- Year and Date
  2009-07-28
- Data Source
  KAKENHI-PROJECT-21790799

1. 内田信一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Ohta Akihito 太田 哲人

太田 哲人 オオタ アキヒト

Research Projects

Research Products

Co-Researchers

Analysis of the role of KLHL3/Cullin3 in PHAIIPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

WNK4キナーゼの腎臓における役割の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 偽性低アルドステロン症II型の分子メカニズム医学のあゆみ2010

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Generation and analysis of knock-in mice carrying pseudohypoaldosteronism type II-causing mutations in the cullin 3 gene.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impaired degradation of WNK by Akt and PKA phosphorylation of KLHL3.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulation of WNK1 kinase by extracellular potassium.2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Targeted disruption of the Wnk4 gene decreases phosphorylation of Na-Cl cotransporter, increases Na excretion and lowers blood pressure2009

Author(s)

Journal Title

Data Source

[Presentation] Acidic motif in WNKs are crucial components for the binding to KLHL32013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Targeted disruption of the Wnk4 gene decreases phosphorylation of Na-Cl cotransporter, increases Na excretion and lowers blood pressure.(poster session), Kyoto Japan, July, 20092009

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Ohta Akihito 太田哲人

太田哲人オオタアキヒト