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Sato Yorino  佐藤 可野

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YORINO SATO  佐藤 可野

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Researcher Number 00511073
Other IDs
Affiliation (Current) 2025: 順天堂大学, 医学部, 助教
Affiliation (based on the past Project Information) *help 2022 – 2024: 順天堂大学, 医学部, 助教
2017 – 2022: 国際医療福祉大学, 医学部, 助教
2016 – 2017: 聖マリアンナ医科大学, 医学部, 研究員
2014 – 2016: 聖マリアンナ医科大学, 医学部, 研究技術員
Review Section/Research Field
Principal Investigator
Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology
Except Principal Investigator
Basic Section 56040:Obstetrics and gynecology-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Obstetrics and gynecology
Keywords
Principal Investigator
高齢不妊 / 卵胞発育 / 卵子老化 / 加齢 / 着床不全 / オートファジー / 卵巣 / 老化 / アンチエイジング / 卵子の質 … More / p16 / 人為的活性化 / Hippoシグナル / IVA / 生殖医学 / 加齢マウス / CNP / aging … More
Except Principal Investigator
早発閉経 / 卵胞活性化 / 卵巣機能不全 / 高齢不妊 / 多嚢胞性卵巣症候群 / 排卵誘発 / メカノバイオロジー / 排卵障害 / IVA / 卵胞活性化療法 / HIPPOシグナル / Hippoシグナル / 低侵襲 / 卵胞発育誘導法 / アンチエイジング / 卵胞発育 / CNP / 卵胞局在 / 規卵巣組織移植 / 卵巣組織移植 / 卵巣組織移植術 / ライブセルイメージング / 不妊治療 / 生殖医学 / 卵胞 Less
  • Research Projects

    (11 results)
  • Research Products

    (37 results)
  • Co-Researchers

    (12 People)
  •  Development of a new approach to treatment of implantation failure by completion of implantation-related factors that are insufficient in aging patients.Principal Investigator

    • Principal Investigator
      佐藤 可野
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Juntendo University
  •  細胞シグナル応答に基づく卵胞活性化療法の改良による卵巣機能不全治療の革新

    • Principal Investigator
      河村 和弘
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Juntendo University
  •  Development of the ovulation induction for infertility with ovulation failure based on mechanobiology

    • Principal Investigator
      河村 和弘
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Juntendo University
  •  オートファジー活性の回復を基軸とした卵子アンチエイジングへの展開Principal Investigator

    • Principal Investigator
      佐藤 可野
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Juntendo University
      International University of Health and Welfare
  •  Antiaging for ovarian follicle development using CNP

    • Principal Investigator
      Kawamura Nanami
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Tokyo Medical and Dental University
      International University of Health and Welfare
  •  Innovation of aging infertility treatment by developing a minimally invasive in vitro activation therapy

    • Principal Investigator
      Kawamura Kazuhiro
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Juntendo University
      International University of Health and Welfare
  •  Developing innovative methods of diagnosing and improving the quality of aging oocytes by targeting the senescence factor p16.Principal Investigator

    • Principal Investigator
      SATO YORNIO
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Juntendo University
      International University of Health and Welfare
  •  Development of a novel method of ovarian tissue grafting applying live cell imaging

    • Principal Investigator
      Kawamura Kazuhiro
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Juntendo University
      International University of Health and Welfare
  •  Development of minimally invasive primordial follicle activation method by Hippo signal inhibitor by drugPrincipal Investigator

    • Principal Investigator
      Sato Yorino
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      International University of Health and Welfare
      St. Marianna University School of Medicine
  •  Establishment of a novel infertility treatment based on the technology of follicle activation

    • Principal Investigator
      Kawamura Kazuhiro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      International University of Health and Welfare
      St. Marianna University School of Medicine
  •  Mechanism of follicle development using CNP on aging micePrincipal Investigator

    • Principal Investigator
      YORINO SATO
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      St. Marianna University School of Medicine

All 2024 2023 2022 2021 2020 2018 2017 2016 2015 Other

All Journal Article Presentation Patent

  • [Journal Article] Effectiveness of supplement ingredients on infertility treatment in advanced aged women2023

    • Author(s)
      Kawamura Kazuhiro、Sato Yorino
    • Journal Title

      Journal of Obstetrics and Gynaecology Research

      Volume: 49 Issue: 8 Pages: 2015-2022

    • DOI

      10.1111/jog.15683

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K18333
  • [Journal Article] Improvement of oocyte quality through the SIRT signaling pathway.2023

    • Author(s)
      Vo KCT、Sato Y、Kawamura K
    • Journal Title

      Reproductive Medicine and Biology

      Volume: 22

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19624
  • [Journal Article] Transcriptomic profiling analysis of human endometrial stromal cells treated with autologous platelet‐rich plasma2023

    • Author(s)
      Kuroda K、Matsumoto A、Horikawa T、Takamizawa S、Ochiai A、Kawamura K、Nakagawa K、Sugiyama R
    • Journal Title

      Reproductive Medicine and Biology

      Volume: 22 Issue: 1

    • DOI

      10.1002/rmb2.12498

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19624, KAKENHI-PROJECT-19H03801
  • [Journal Article] Improvement of oocyte quality through the SIRT signaling pathway.2023

    • Author(s)
      Vo KCT、Sato Y、Kawamura K
    • Journal Title

      Reproductive Medicine and Biology

      Volume: 22

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03801
  • [Journal Article] Anti‐Mullerian hormone for screening, diagnosis, evaluation, and prediction: A systematic review and expert opinions2023

    • Author(s)
      Iwase Akira、Asada Yoshimasa、Sugishita Yodo、Osuka Satoko、Kitajima Michio、Kawamura Kazuhiro
    • Journal Title

      Journal of Obstetrics and Gynaecology Research

      Volume: 50 Issue: 1 Pages: 15-39

    • DOI

      10.1111/jog.15818

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K18333, KAKENHI-PROJECT-21K09521, KAKENHI-PROJECT-23K08865
  • [Journal Article] Development of a recombinant murine luteinizing hormone-binding protein as a selective hormone inhibitor2022

    • Author(s)
      Yamaguchi Y、Yorino Sato Y、Kawamura K
    • Journal Title

      Journal of Mammalian Ova Research

      Volume: 39 Pages: 35-47

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03801
  • [Journal Article] 高齢不妊女性に対するサプリメントの有用性2022

    • Author(s)
      山口祐之 , 佐藤可野 , 河村和弘
    • Journal Title

      Journal of Mammalian Ova Research

      Volume: 39 Pages: 27-34

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03801
  • [Journal Article] Development of a recombinant murine luteinizing hormone-binding protein as a selective hormone inhibitor2022

    • Author(s)
      Yamaguchi Y、Yorino Sato Y、Kawamura K
    • Journal Title

      Journal of Mammalian Ova Research

      Volume: 39 Pages: 35-47

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19624
  • [Journal Article] 高齢不妊女性に対するサプリメントの有用性2022

    • Author(s)
      山口祐之 , 佐藤可野 , 河村和弘
    • Journal Title

      Journal of Mammalian Ova Research

      Volume: 39 Pages: 27-34

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K19624
  • [Journal Article] Short-term resveratrol treatment restored the quality of oocytes in aging mice.2022

    • Author(s)
      Okamoto, N., Sato, Y., Kawagoe, Y., Shimizu, T., Kawamura, K.
    • Journal Title

      Aging

      Volume: 14 Issue: 14 Pages: 5628-5640

    • DOI

      10.18632/aging.204157

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K19607, KAKENHI-PROJECT-20H03583, KAKENHI-PROJECT-18K19624, KAKENHI-PROJECT-19H03801
  • [Journal Article] Effects of Hochuekkito, a traditional Japanese medicine (Kampo), on reproduction of aging female mice2021

    • Author(s)
      Vo Kim Cat Tuyen、Sato Yorino、Kawagoe Yuta、Kawamura Kazuhiro
    • Journal Title

      Reproductive Medicine and Biology

      Volume: 21 Issue: 1

    • DOI

      10.1002/rmb2.12425

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03801, KAKENHI-PROJECT-18K19624
  • [Journal Article] Ageing and chronic disease-related changes in the morphometric characteristics of ovarian follicles in cynomolgus monkeys (<i>Macaca fascicularis</i>)2021

    • Author(s)
      Grin L、Vo K C T、Sato Y、Mizrachi Y、Kohara M、Sankai T、Kawamura K
    • Journal Title

      Human Reproduction

      Volume: 36 Issue: 10 Pages: 2732-2742

    • DOI

      10.1093/humrep/deab191

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03801, KAKENHI-PROJECT-18K19624
  • [Journal Article] Rapamycin treatment maintains developmental potential of oocytes in mice and follicle reserve in human cortical fragments grafted into immune-deficient mice2020

    • Author(s)
      Yorino Sato、Kawamura Kazuhiro
    • Journal Title

      Molecular and Cellular Endocrinology

      Volume: 504 Pages: 110694-110694

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19624
  • [Journal Article] Rapamycin treatment maintains developmental potential of oocytes in mice and follicle reserve in human cortical fragments grafted into immune-deficient mice2020

    • Author(s)
      Yorino Sato, Kawamura K
    • Journal Title

      Mol Cell Endocrinol

      Volume: 504 Pages: 110694-110694

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05476
  • [Journal Article] Placensin is a glucogenic hormone secreted by human placenta.2020

    • Author(s)
      Yu Y, He JH, Hu LL, Jiang LL, Fang L, Yao GD, Wang SJ, Yang Q, Guo Y, Liu L, Shang T, Sato Y, Kawamura K, Hsueh AJ, Sun YP
    • Journal Title

      EMBO Rep

      Volume: 24

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19624
  • [Journal Article] CXCL5-CXCR2 signaling is a senescence-associated secretory phenotype in preimplantation embryos.2020

    • Author(s)
      Kawagoe Y, Kawashima I, Sato Y;Okamoto N, Matsubara K, Kawamura K
    • Journal Title

      Aging Cell.

      Volume: 19

    • NAID

      120007181848

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K19624
  • [Journal Article] Heterosis extends the reproductive ability in aged female mice†2018

    • Author(s)
      Ozawa Yusuke、Watanabe Kenji、Toda Toshihiko、Shibuya Shuichi、Okumura Nobuaki、Okamoto Naoki、Sato Yorino、Kawashima Ikko、Kawamura Kazuhiro、Shimizu Takahiko
    • Journal Title

      Biology of Reproduction

      Volume: 100 Issue: 4 Pages: 1082-1089

    • DOI

      10.1093/biolre/ioy260

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19624, KAKENHI-PROJECT-15K20167, KAKENHI-PROJECT-16H05476
  • [Journal Article] 喫煙と早発卵巣不全の関連性に関するアンケート調査2017

    • Author(s)
      川越雄太、佐藤可野、河村和弘
    • Journal Title

      日本受精着床学会雑誌

      Volume: 34 Pages: 247-250

    • Data Source
      KAKENHI-PROJECT-16H05476
  • [Journal Article] Infertility Treatment in Primary Ovarian Insufficiency: Fertility Preservation and?In Vitro?Activation2017

    • Author(s)
      Yorino Sato, Nanami Kawamura, Kazuhiro Kawamura
    • Journal Title

      Journal of Gynecology and Womens Health

      Volume: 7 Issue: 1 Pages: 1-4

    • DOI

      10.19080/jgwh.2017.07.555704

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K11116, KAKENHI-PROJECT-16H05476, KAKENHI-PROJECT-15K15613
  • [Journal Article] グラビア・目で見る遺伝子異常と婦人科内分泌疾患―早発卵巣不全―2017

    • Author(s)
      河村和弘・佐藤可野・鈴木直
    • Journal Title

      HORMONE FRONTIER IN GYNECOLOGY

      Volume: 24 Pages: 4-7

    • Data Source
      KAKENHI-PROJECT-16H05476
  • [Journal Article] In Vitro Activation of Follicles and Fresh Tissue Auto-transplantation in Primary Ovarian Insufficiency Patients.2016

    • Author(s)
      Zhai J, Yao G, Dong F, Bu Z, Cheng Y, Sato Y, Hu L, Zhang Y, Wang J, Dai S, Li J, Sun J, Hsueh AJ, Kawamura K, Sun Y
    • Journal Title

      J Clin Endocrinol Metab

      Volume: 101 Issue: 11 Pages: 4405-4412

    • DOI

      10.1210/jc.2016-1589

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15613, KAKENHI-PROJECT-16K20217, KAKENHI-PROJECT-16H05476, KAKENHI-PUBLICLY-26114510
  • [Journal Article] Actin polymerization-enhancing drugs promote ovarian follicle growth mediated by the Hippo signaling effector YAP.2015

    • Author(s)
      Cheng Y, Feng Y, Jansson L, Sato Y, Deguchi M,Kawamura K, Hsueh AJ
    • Journal Title

      FASEB J

      Volume: 29 Issue: 6 Pages: 2423-2430

    • DOI

      10.1096/fj.14-267856

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15613, KAKENHI-PROJECT-26861346, KAKENHI-PUBLICLY-26114510, KAKENHI-PROJECT-24390376
  • [Journal Article] The role of menstrual cycle phase and AMH levels in breast cancer patients whose ovarian tissue was cryopreserved for oncofertility treatment.2015

    • Author(s)
      Takae S, Sugishita Y, Yoshioka N, Hoshina M, Horage Y, Sato Y, Nishijima C, Kawamura K, Suzuki N
    • Journal Title

      J Assist Reprod Genet

      Volume: 32 Issue: 2 Pages: 305-312

    • DOI

      10.1007/s10815-014-0392-z

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15613, KAKENHI-PROJECT-26861346, KAKENHI-PUBLICLY-26114510, KAKENHI-PROJECT-24390376
  • [Patent] 組織幹細胞の老化抑制剤2024

    • Inventor(s)
      河村和弘 , 川越雄太 , 佐藤可野
    • Industrial Property Rights Holder
      学校法人順天堂
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2024-056858
    • Filing Date
      2024
    • Data Source
      KAKENHI-PROJECT-23K18333
  • [Presentation] ヒト始原生殖細胞は内在性レトロウイルスKを発現する2023

    • Author(s)
      小林睦 , 小林美里 , 川越雄太 , 佐藤可乃 , Keiko Shioda , Hikari Hagihara , Junko Odajima , Maria Ericsson , 北出真理 , 板倉敦夫 , Toshi Shioda , 河村和弘
    • Organizer
      第68回日本生殖医学会学術講演会・総会
    • Data Source
      KAKENHI-PROJECT-23K18333
  • [Presentation] ヒト配偶子における内在性レトロウイルス発現様式の解明2023

    • Author(s)
      小林 睦 , 小林 美里 , 川越雄太 , 佐藤可野 , Hagihara Hikari , Odajima Junko , Shioda Keiko , Ericsson Maria , 北出 真理 , 板倉 敦夫 , Shioda Toshi , 河村 和弘
    • Organizer
      第64回日本卵子学会学術集会
    • Data Source
      KAKENHI-PROJECT-23K18333
  • [Presentation] 高ゴナドトロピン血症による卵胞発育および排卵障害は高 LH 環境が起因する2022

    • Author(s)
      山口祐之, 佐藤可野, 河村和弘
    • Organizer
      第63回日本卵子学会学術集会
    • Data Source
      KAKENHI-PROJECT-19H03801
  • [Presentation] 高ゴナドトロピン血症による卵胞発育および排卵障害は高 LH 環境が起因する2022

    • Author(s)
      山口祐之, 佐藤可野, 河村和弘
    • Organizer
      第63回日本卵子学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K19624
  • [Presentation] Hippoシグナリング抑制を基盤とする 新規卵巣刺激法の開発2020

    • Author(s)
      河村和弘, 佐藤可野, 川越雄太
    • Organizer
      第10回国際医療福祉大学学会学術大会
    • Data Source
      KAKENHI-PROJECT-18K19624
  • [Presentation] マイクロニードルによる卵巣穿刺刺激がマウス卵巣内未成熟卵胞の発育に及ぼす影響2020

    • Author(s)
      針金花織, 立原昂平, 田村美穂, 澁木菜央, 伊藤謙, 佐藤勝祥, 渡邊潤, 小林仁, 河村和弘, 横尾正樹
    • Organizer
      第113回日本繁殖生物学会(オンライン)開催
    • Data Source
      KAKENHI-PROJECT-18K19624
  • [Presentation] ヒト胎盤由来の新たな糖新生促進ホルモン(Placensin)の同定とその機能解析2020

    • Author(s)
      河村和弘, 佐藤可野
    • Organizer
      第25回日本生殖内分泌学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K19624
  • [Presentation] マウスおよびウシIVF 胚に対する超早期妊娠因子抗体の反応2020

    • Author(s)
      門岡憲, 平田統一, 片平睦子, 中村啓哉, 横尾正樹, 川越雄太, 佐藤可野, 河村和弘, 松原和衛
    • Organizer
      第61回日本卵子学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K19624
  • [Presentation] mTOR阻害剤による卵巣機能不全患者の卵巣予備能温存法の開発2020

    • Author(s)
      佐藤可野, 岡本直樹, 川越雄太, 河村和弘
    • Organizer
      第38回日本受精着床学会総会・学術講演会
    • Data Source
      KAKENHI-PROJECT-18K19624
  • [Presentation] 高齢マウス胚での細胞老化関連分泌因子CXCL5の発現増加と妊娠率の低下2020

    • Author(s)
      川越雄太, 佐藤可野, 河村和弘
    • Organizer
      第25回日本生殖内分泌学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K19624
  • [Presentation] mTOR阻害剤による卵巣予備能温存法の開発2020

    • Author(s)
      佐藤可野,岡本直樹, 川越雄太, 河村和弘
    • Organizer
      第25回日本生殖内分泌学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K19624
  • [Presentation] 喫煙と早発卵巣機能不全:喫煙は早発卵巣機能不全の発症因子、増悪因子となりうるか2017

    • Author(s)
      河村和弘、佐藤可野
    • Organizer
      第32回 平成28年度助成研究発表会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05476
  • [Presentation] 卵胞発育を制御する新たな局所因子―Ctype natriuretic peptide(CNP)

    • Author(s)
      佐藤可野
    • Organizer
      生殖医学会
    • Place of Presentation
      京王プラザ 東京都 新宿区
    • Year and Date
      2014-12-04 – 2014-12-05
    • Data Source
      KAKENHI-PROJECT-26861346
  • 1.  Kawamura Kazuhiro (10344756)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 34 results
  • 2.  岡本 直樹 (80714360)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 4 results
  • 3.  川越 雄太 (10609077)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 4.  Kawamura Nanami (70323152)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 5.  川島 一公 (40633946)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  山海 直 (80300937)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 7.  横尾 正樹 (10396541)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  小林 仁 (40234827)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 9.  池内 真志 (90377820)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  高江 正道
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  吉岡 伸人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  清水 孝彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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