SAKABE Masahide 坂部正英

Researcher Number	00525983
Affiliation (based on the past Project Information) *help	2009 – 2017: Nara Medical University, 医学部, 助教 2013: 奈良県立医科大学, 先端医学研究機構生命システム医科学分野, 循環器システム医科学研究室 2012: 奈良県立医科大学, 循環器システム医科学, 助教 2010: 奈良県立医科大学, 先端医学研究機構生命システム医科学分野循環器システム医科学研究室, 助教
Review Section/Research Field	Principal Investigator General anatomy (including Histology/Embryology) / General anatomy (including histology/embryology) / Biological Sciences Except Principal Investigator Embryonic/Neonatal medicine / Cardiovascular medicine / Circulatory organs internal medicine / Pediatrics / Neurology
Keywords	Principal Investigator シグナル伝達 / 心内膜床 / 心臓発生 / 形態形成 / EMT / Notch / 器官形成 / 遺伝子発現調節 / 先天性心疾患 / 内皮間葉形質転換 … More / 心内膜床培養モデル / Notch情報伝達系 / 発生遺伝学 / 心臓発生学 / 組織形成 / 細胞分化 / 遺伝子解析 / 心内膜床形成 / 大血管転位 / 心奇形 / レチノイン酸 / 奇形学 / 先天異常学 … More Except Principal Investigator シグナル伝達 / 形態形成 / 心血管発生 / 転写調節因子 / 心血管系 / 血管内皮細胞 / 心血管発生・形態形成 / 血管内皮 / 発生 / 発生分化 / 心臓 / 血管 / 内皮細胞 / 心血管形態形成 / 発生・形態形成 / ノックアウトマウス / 先天性心疾患 / 転写調節 / 遺伝子発現調節 / 循環器系 / 細胞間シグナル / VEGF / G蛋白活性調節因子 / Endothelial cells / VEGF signal / G-protein / G蛋白 / VEGFシグナル / 血管新生 / 先天性心血管奇形 / トランスジェニックマウス / 分子心臓病態学 / 骨格筋疾患 / 筋肉 / リン酸化酵素 Less

Novel approaches to analyze the regulatory mechanisms of cardiovascular genes in development and morphogenesis
- Principal Investigator
  
  NAKAGAWA Osamu
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  National Cardiovascular Center Research Institute
Signaling pathways that regulate cardiovascular development and morphogenesis
- Principal Investigator
  
  Nakagawa Osamu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  National Cardiovascular Center Research Institute
心臓中隔や弁の前駆組織をつくりだす部位特異的な細胞運動とそれを誘導するメカニズムPrincipal Investigator
- Principal Investigator
  
  坂部正英
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nara Medical University
心臓形態形成を制御する新規シグナル伝達ネットワークの解明とその意義Principal Investigator
- Principal Investigator
  
  坂部正英
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Nara Medical University
Regulation of vascular endothelial cells by signaling molecules
- Principal Investigator
  
  Hisaki Hayashi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Aichi Medical University
Significance of a new endothelial gene TMEM100 in vascular development and disease
- Principal Investigator
  
  NAKAGAWA Osamu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  National Cardiovascular Center Research Institute
  Nara Medical University
Transcriptional regulation of cardiovascular development
- Principal Investigator
  
  NAKAGAWA Osamu
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  National Cardiovascular Center Research Institute
  Nara Medical University
New Transgenic Mouse System to Analyze Functional Mechanisms of Transcription Factors
- Principal Investigator
  
  NAKAGAWA Osamu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Nara Medical University
Roles of ununiform cellular signaling during cardiac morphogenesisPrincipal Investigator
- Principal Investigator
  
  SAKABE Masahide
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Nara Medical University
Investigation of the mechanisms of congenital heart defects using developmental engineering.Principal Investigator
- Principal Investigator
  
  SAKABE Masahide
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Nara Medical University
Significance of novel protein kinase in muscle function and disease
- Principal Investigator
  
  NAKAGAWA Osamu
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Nara Medical University

All 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Book

[Book] TMEM100, a novel intracellular transmembrane protein essential for cardiovascular development. In Etiology and morphogenesis of congenital heart disease. Ed. by Srivastava D, Keller BB, Markwald R, Yamagishi H, Nakanishi T.2017
- Author(s)
  Mizuta K, Sakabe M, Somekawa S, Saito Y, Nakagawa O.
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-15K15407
[Book] TMEM100, a novel intracellular transmembrane protein essential for cardiovascular development. In Etiology and morphogenesis of congenital heart disease. Ed. by Srivastava D, Keller BB, Markwald R, Yamagishi H, Nakanishi T.2017
- Author(s)
  Mizuta K, Sakabe M, Somekawa S, Saito Y, Nakagawa O.
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-15H04883
[Book] Roles of endothelial Hrt genes for vascular development. In Etiology and morphogenesis of congenital heart disease. Ed. by Srivastava D, Keller BB, Markwald R, Yamagishi H, Nakanishi T.2017
- Author(s)
  Sakabe M, Morioka T, Kimura H, Nakagawa O.
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-15H04883
[Book] 心臓発生に働く転写調節因子の心肥大・心機能調節における意義 237巻6号2011
- Author(s)
  中川修, 林寿来, 坂部正英
- Publisher
  医学のあゆみ
- Data Source
  KAKENHI-PROJECT-20599016
[Journal Article] Pharyngeal arch artery defects and lethal malformations of the aortic arch and its branches in mice deficient for the Hrt1/Hey1 transcription factor.2016
- Author(s)
  Fujita M, Sakabe M, Ioka T, Watanabe Y, Kinugasa-Katayama Y, Tsuchihashi T, Utset MF, Yamagishi H, Nakagawa O.
- Journal Title
  
  Mechanisms of Development
  
  Volume: 139 Pages: 65-73
- DOI
  10.1016/j.mod.2015.11.002
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04883, KAKENHI-PROJECT-26860127, KAKENHI-PROJECT-16H05359
[Journal Article] TMEM100, a novel intracellular transmembrane protein essential for cardiovascular development.2016
- Author(s)
  Mizuta K, Sakabe M, Somekawa S, Saito Y, Nakagawa O.
- Journal Title
  
  Etiology and morphogenesis of congenital heart disease
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04883
[Journal Article] TMEM100, a novel intracellular transmembrane protein essential for cardiovascular development.2016
- Author(s)
  Mizuta K, Sakabe M, Somekawa S, Saito Y, Nakagawa O
- Journal Title
  
  Etiology and morphogenesis of congenital heart disease
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670492
[Journal Article] TMEM100, a novel intracellular transmembrane protein essential for cardiovascular development.2016
- Author(s)
  Mizuta K, Sakabe M, Somekawa S, Saito Y, Nakagawa O.
- Journal Title
  
  Etiology and morphogenesis of congenital heart disease
  
  Volume: in press
- Data Source
  KAKENHI-PROJECT-15K15407
[Journal Article] Roles of endothelial Hrt genes for vascular development.2016
- Author(s)
  Sakabe M, Morioka T, Kimura H, Nakagawa O.
- Journal Title
  
  Etiology and morphogenesis of congenital heart disease
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04883
[Journal Article] Impairment of endothelial-mesenchymal transformation during atrioventriucular cushion formation in Tmem100 null embryo2015
- Author(s)
  Mizuta K., Sakabe M., Ioka T., Hashimoto A., Ioka T., Sakai C., Okumura K., Hattammaru M., Fujita M., Araki M., Somekawa S., Saito Y., Nakagawa O
- Journal Title
  
  Developmental Dynamics
  
  Volume: 244 Issue: 1 Pages: 31-42
- DOI
  10.1002/dvdy.24216
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25111728, KAKENHI-PROJECT-25670492, KAKENHI-PROJECT-25293187
[Journal Article] 心血管形態形成におけるHrt/Hey転写調節因子の意義2015
- Author(s)
  渡邉裕介、久光隆、片山由美、荒木睦、石井修平、藤田匡秀、坂部正英、中川修.
- Journal Title
  
  循環器病研究の進歩
  
  Volume: 36 Pages: 74-82
- Data Source
  KAKENHI-PROJECT-15H04883
[Journal Article] An important role of endothelial Hairy-related transcription factors in mouse vascular development2014
- Author(s)
  Morioka T, Sakabe M, Ioka T, Iguchi T, Mizuta K, Hattammaru M, Sakai C, Itoh M, Sato GE, Hashimoto A, Fujita M, Okumura K, Araki M, Xin M, Pedersen RA, Utset MF, Kimura H, Nakagawa O
- Journal Title
  
  Genesis
  
  Volume: 52 Issue: 11 Pages: 897-906
- DOI
  10.1002/dvg.22825
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23390274, KAKENHI-PUBLICLY-25111728, KAKENHI-PROJECT-25460247
[Journal Article] Tmem100, an ALK1 signaling-dependent gene essential for arterial endothelium differentiation and vascular morphogenesis2012
- Author(s)
  Somekawa S, Imagawa K, Hayashi H, Sakabe M, Ioka T, Sato GE, Inada K, Iwamoto T, Mori T, Uemura S, Nakagawa O, Saito Y
- Journal Title
  
  Proc. Nat. Acad. Sci. USA
  
  Volume: 109(30 Pages: 12064-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659425
[Journal Article] 心臓発生に働く転写調節因子の心肥大・心機能調節における意義2011
- Author(s)
  中川修　林寿来　坂部正英
- Journal Title
  
  医学のあゆみ
  
  Volume: 237 Pages: 683-687
- Data Source
  KAKENHI-PROJECT-23659425
[Journal Article] High levels of maternal retinoic acid induce the transposition of great arteries (TGA) by suppressing the Tbx2-Tgfβ2 pathway during outflow cushion formation.
- Author(s)
  Sakabe M., Nakajima Y., Kokubo H., Saga Y.
- Journal Title
  
  Development (改訂中)
- Data Source
  KAKENHI-PROJECT-21790194
[Presentation] 血管内皮細胞におけるBMP9/BMP10-ALK1シグナル下流遺伝子群の解析2015
- Author(s)
  荒木睦、渡邉裕介、坂部正英、久光隆、中尾周、藤田匡秀、片山由美、井岡朋子、中川修
- Organizer
  日本心血管内分泌代謝学会学術総会
- Place of Presentation
  神戸市
- Year and Date
  2015-12-12
- Data Source
  KAKENHI-PROJECT-15H04883
[Presentation] 血管内皮細胞におけるBMP9/BMP10-ALK1シグナル下流遺伝子群の解析2015
- Author(s)
  片山由美、渡邉裕介、水田賢、坂部正英、井岡朋子、荒木睦、石井修平、染川智、斎藤能彦、中川修
- Organizer
  日本血管生物医学会学術総会
- Place of Presentation
  神戸市
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-15H04883
[Presentation] 血管内皮細胞におけるBMP9/BMP10-ALK1シグナル下流遺伝子群の解析2015
- Author(s)
  荒木睦、渡邉裕介、坂部正英、久光隆、中尾周、藤田匡秀、片山由美、井岡朋子、中川修
- Organizer
  日本心血管内分泌代謝学会学術総会
- Place of Presentation
  神戸市
- Year and Date
  2015-12-12
- Data Source
  KAKENHI-PROJECT-25670492
[Presentation] 血管内皮細胞におけるBMP9/BMP10-ALK1シグナル下流遺伝子群の解析2015
- Author(s)
  片山由美、渡邉裕介、水田賢、坂部正英、井岡朋子、荒木睦、石井修平、染川智、斎藤能彦、中川修
- Organizer
  日本血管生物医学会学術総会
- Place of Presentation
  神戸市
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-15K15407
[Presentation] 血管内皮細胞におけるBMP9/BMP10-ALK1シグナル下流遺伝子群の解析2015
- Author(s)
  片山由美、渡邉裕介、水田賢、坂部正英、井岡朋子、荒木睦、石井修平、染川智、斎藤能彦、中川修
- Organizer
  日本血管生物医学会学術総会
- Place of Presentation
  神戸市
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-25670492
[Presentation] Significance of endothelial Hairy-related transcription factors in embryonic vascular development2014
- Author(s)
  Nakagawa O, Sakabe M
- Organizer
  18th International Vascular Biology Meeting
- Place of Presentation
  京都市
- Year and Date
  2014-04-14
- Invited
- Data Source
  KAKENHI-PROJECT-23390274
[Presentation] Significance of endothelial Hairy-related transcription factors in embryonic vascular development2014
- Author(s)
  Nakagawa O, Sakabe M
- Organizer
  18th International Vascular Biology Meeting
- Place of Presentation
  京都市
- Year and Date
  2014-09-10
- Invited
- Data Source
  KAKENHI-PROJECT-25670492
[Presentation] Impairment of endothelial-mesenchymal transformation during atrioventricular cushion formation in Tmem100 null embryos2014
- Author(s)
  Mizuta K, Sakabe M, Hashimoto A, Ioka T, Sakai C, Okumura K, Hattammaru M, Fujita M, Araki M, Somekawa S, Saito Y, Nakagawa O
- Organizer
  The Conference on Bioactive Peptides for Cell-Cell Communication 2014
- Place of Presentation
  京都市
- Year and Date
  2014-09-10
- Data Source
  KAKENHI-PROJECT-25670492
[Presentation] NotchおよびBMP-ALK1系の下流転写調節因子Hrtファミリーの内皮分化・血管形成における意義2013
- Author(s)
  坂部正英、森岡崇、井岡朋子、水田賢、酒井千浩、八反丸美和、林寿来、橋本彩、木下友希、藤田匡秀、奥村和生、倉岡大希、Utset MF、Olson EN、木村弘、中川修
- Organizer
  日本心血管内分泌代謝学会学術総会
- Place of Presentation
  吹田市
- Year and Date
  2013-11-23
- Data Source
  KAKENHI-PROJECT-23390274
[Presentation] Roles of Hrt family of Notch downstream transcription factors in developing endothelium during vascular formation2013
- Author(s)
  坂部正英
- Organizer
  日本Notch研究会
- Data Source
  KAKENHI-PROJECT-23790232
[Presentation] Roles of the Hrt family of Notch downstream transcription factors in endothelium during vascular development2013
- Author(s)
  Sakabe M, Morioka T, Iguchi T, Ioka T, Mizuta M, Hattammaru M, Sato GE, Ito M, Hayashi H, Utset MF, Olson EN, Kimura H, Nakagawa O
- Organizer
  The 7th TAKAO International Symposium
- Place of Presentation
  東京都
- Year and Date
  2013-07-14
- Data Source
  KAKENHI-PROJECT-23390274
[Presentation] Roles of the Hrt family of Notch downstream transcription factors in endothelium during cardiovascular morphogenesis2013
- Author(s)
  Sakabe M, Morioka T, Iguchi T, Ioka T, Mizuta K, Hattammaru M, Sato GE, Ito M, Hayashi H, Utset MF, Olson EN, Kimura H, Nakagawa O
- Organizer
  日本血管生物医学会学術集会
- Place of Presentation
  吹田市
- Year and Date
  2013-09-28
- Data Source
  KAKENHI-PROJECT-23390274
[Presentation] Hrt転写調節因子の内皮分化と血管形成における意義2013
- Author(s)
  坂部正英、森岡崇、井岡朋子、稲田賢、佐藤玄基、伊藤宗洋、八反丸美和、橋本彩、酒井千浩、林寿来、Utset MF、Olson EN、木村弘、中川修
- Organizer
  日本先天異常学会学術集会
- Place of Presentation
  吹田市
- Year and Date
  2013-07-23
- Data Source
  KAKENHI-PROJECT-23390274
[Presentation] Roles of Hairy-Related Transcription factors in developing endothelium during vascular formation2012
- Author(s)
  坂部正英
- Organizer
  日本血管生物医学会
- Data Source
  KAKENHI-PROJECT-23790232
[Presentation] Roles of Hairy-related transcription factors in developing vascular endothelial cells2012
- Author(s)
  森岡崇　林寿来　井岡朋子　坂部正英　木村弘　中川修
- Organizer
  日本内科学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23659425
[Presentation] Roles of Hairy-related transcription factors in developing vascular endothelial cells2011
- Author(s)
  Takashi Morioka, Masahide Sakabe, Hisaki Hayashi, Tomoko Ioka, Tomoko Fujita, Genki Sato, Munehiro Ito, Ken Inada, Manuel F. Utset, Eric N. Olson, Hiroshi Kimura, Osamu Nakagawa
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23659425
[Presentation] Ectopic retinoic acid signaling induces transposition of great arteries (TGA) via suppressing Tbx2 expression during outflow cushion formation.2010
- Author(s)
  Sakabe M, Nakajima Y, Kokubo H, Saga Y.
- Organizer
  International Symposium on Cardiovascular Endocrinology and Metabolism CVEM 2010
- Place of Presentation
  Nara
- Data Source
  KAKENHI-PROJECT-21790194
[Presentation] T-box transcription factor Tbx2 is a key factor in the pathogenesis of congenital heart diseases including transposition of great arteries.2010
- Author(s)
  坂部正英, 中島裕司, 小久保博樹, 相賀裕美子
- Organizer
  第33回日本分子生物学会ワークショップ
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21790194
[Presentation] Ectopic retinoic acid signaling induces transposition of great arteries (TGA) via suppressing Tbx2 expression during outflow cushion formation2010
- Author(s)
  Masahide Sakabe
- Organizer
  分子生物学会
- Place of Presentation
  神戸(神戸ポートアイランド)
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21790194
[Presentation] Ectopic retinoic acid signaling induces transposition of great arteries (TGA) via suppressing Tbx2 expression during outflow cushion formation2010
- Author(s)
  Masahide Sakabe
- Organizer
  国際心血管内分泌代謝学会
- Place of Presentation
  奈良(奈良県新公会堂)
- Year and Date
  2010-04-01
- Data Source
  KAKENHI-PROJECT-21790194
[Presentation] Ectopic retinoic acid signaling induces transposition of great arteries (TGA) viasuppressing Tbx2 expression during outflow cushion formation2009
- Author(s)
  Masahide Sakabe
- Organizer
  分子生物学会
- Place of Presentation
  横浜(パシフィコ横浜)
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21790194
[Presentation] Ectopic retinoic acid signaling induces transposition of great arteries (TGA) via suppressing Tbx2 expression during outflow cushion formation.2009
- Author(s)
  坂部正英, 中島裕司, 小久保博樹, 相賀裕美子
- Organizer
  第32回日本分子生物学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21790194
[Presentation] レチノイン酸が引き起こす大血管転位発症メカニズムの解明2009
- Author(s)
  坂部正英, 中島裕司, 小久保博樹, 相賀裕美子
- Organizer
  第8回心臓血管発生研究会
- Place of Presentation
  福島
- Data Source
  KAKENHI-PROJECT-21790194
[Presentation] Roles of the Hrt family of Notch downstream transcription factors in endothelium during cardiovascular morphogenesis
- Author(s)
  Masahide Sakabe
- Organizer
  The 18th International Vascular Biology Meeting
- Place of Presentation
  京都　みやこメッセ
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PUBLICLY-25111728
[Presentation] Roles of the Hrt family of Notch downstream transcription factors in endothelium during cardiovascular morphogenesis
- Author(s)
  坂部正英
- Organizer
  日本血管生物医学会
- Place of Presentation
  千里阪急ホテル
- Data Source
  KAKENHI-PROJECT-25460247
[Presentation] Significance of endothelial Hairy-related transcription factors in embryonic vascular development
- Author(s)
  中川修　坂部正英
- Organizer
  18th International Vascular Biology Meeting
- Place of Presentation
  京都府京都市
- Invited
- Data Source
  KAKENHI-PROJECT-25670492
[Presentation] Hrt転写調節因子の内皮分化と血管形成における意義
- Author(s)
  坂部正英　森岡崇　井岡朋子　稲田賢　佐藤玄基　伊藤宗洋　八反丸美和　橋本彩　酒井千浩　林寿来　Manuel Utset　Eric Olson　木村弘　中川修
- Organizer
  日本先天異常学会（学術集会）
- Place of Presentation
  大阪府吹田市
- Data Source
  KAKENHI-PROJECT-23390274
[Presentation] NotchおよびBMP-ALK1系の下流転写調節因子Hrtファミリーの内皮分化・血管形成における意義
- Author(s)
  坂部正英
- Organizer
  日本心血管内分泌代謝学会
- Place of Presentation
  千里ライフサイエンスセンター
- Data Source
  KAKENHI-PROJECT-25460247
[Presentation] Roles of the Hrt family of Notch downstream transcription factors in endothelium during vascular development
- Author(s)
  坂部正英　森岡崇　井口朋子　井岡朋子　水田賢　八反丸美和　佐藤玄基　伊藤宗洋　林寿来　Manuel Utset　Eric Olson　木村弘　中川修
- Organizer
  The 7th TAKAO International Symposium
- Place of Presentation
  東京都渋谷区
- Data Source
  KAKENHI-PROJECT-23390274
[Presentation] NotchおよびBMP-ALK1系の下流転写調節因子Hrtファミリーの内皮分化・血管形成における意義
- Author(s)
  坂部正英　森岡崇　井岡朋子　水田賢　酒井千浩　八反丸美和　林寿来　橋本彩　木下友希　藤田匡秀　奥村和生　倉岡大希　Manuel Utset　Eric Olson　木村弘　中川修
- Organizer
  日本心血管内分泌代謝学会（学術総会）
- Place of Presentation
  大阪府吹田市
- Data Source
  KAKENHI-PROJECT-23390274
[Presentation] Significance of endothelial Hairy-related transcription factors in embryonic vascular development
- Author(s)
  中川修　坂部正英
- Organizer
  18th International Vascular Biology Meeting
- Place of Presentation
  京都府京都市
- Invited
- Data Source
  KAKENHI-PROJECT-23390274
[Presentation] Roles of Hrt family of Notch downstream transcription factors during endocardial cushion development
- Author(s)
  坂部正英　水田賢　酒井千浩　井岡朋子　森岡崇　八反丸美和　橋本彩　藤田匡秀　倉岡大希　奥村和生　林寿来　中川修
- Organizer
  分子生物学会（年会）
- Place of Presentation
  兵庫県神戸市
- Data Source
  KAKENHI-PROJECT-23390274
[Presentation] Roles of the Hrt family of Notch downstream transcription factors in endothelium during vascular development
- Author(s)
  Mashaide Sakabe
- Organizer
  The 7th TAKAO International Symposium
- Place of Presentation
  国立オリンピック記念青少年総合センター
- Data Source
  KAKENHI-PROJECT-25460247
[Presentation] Roles of Hrt family of Notch downstream transcription factors during endocardial cushion development
- Author(s)
  坂部正英　水田賢　酒井千浩　井岡朋子　森岡崇　八反丸美和　橋本彩　藤田匡秀　倉岡大希　奥村和生　林寿来　中川修
- Organizer
  分子生物学会（年会）
- Place of Presentation
  兵庫県神戸市
- Data Source
  KAKENHI-PROJECT-25670492
[Presentation] NotchおよびBMP-ALK1系の下流転写調節因子Hrtファミリーの内皮分化・血管形成における意義
- Author(s)
  坂部正英　森岡崇　井岡朋子　水田賢　酒井千浩　八反丸美和　林寿来　橋本彩　木下友希　藤田匡秀、奥村和生　倉岡大希　Manuel　Utset　Eric　Olson　木村弘　中川修
- Organizer
  日本心血管内分泌代謝学会（学術総会）
- Place of Presentation
  大阪府吹田市
- Data Source
  KAKENHI-PROJECT-25670492
[Presentation] Roles of Hrt family of Notch downstream transcription factors during endothelial cushion development
- Author(s)
  坂部正英
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PUBLICLY-25111728
[Presentation] Roles of the Hrt family of Notch downstream transcription factors in endothelium during cardiovascular morphogenesis
- Author(s)
  坂部正英　森岡崇　井口朋子　井岡朋子　水田賢　八反丸美和　佐藤玄基　伊藤宗洋　林寿来　Manuel Utset　Eric Olson　木村弘　中川修
- Organizer
  日本血管生物医学会（学術集会）
- Place of Presentation
  大阪府吹田市
- Data Source
  KAKENHI-PROJECT-23390274
[Presentation] Roles of the Hrt family of Notch downstream transcription factors in endothelium during cardiovascular morphogenesis
- Author(s)
  Masahide Sakabe
- Organizer
  International Vascular Biology Meeting (IVBM)
- Place of Presentation
  京都　みやこメッセ
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PROJECT-25460247
[Presentation] Roles of Hrt family of Notch downstream transcription factors during endocardial cushion development
- Author(s)
  坂部正英
- Organizer
  分子生物学会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-25460247
[Presentation] Hrt転写調節因子の内皮分化と血管形成における意義
- Author(s)
  坂部正英
- Organizer
  日本先天異常学会
- Place of Presentation
  千里ライフサイエンスセンター
- Data Source
  KAKENHI-PROJECT-25460247

1. NAKAGAWA Osamu (40283593)

# of Collaborated Projects: 8 results

# of Collaborated Products: 36 results
2. HAYASHI Hisaki (30533715)

# of Collaborated Projects: 6 results

# of Collaborated Products: 16 results
3. YAMAGISHI Hiroyuki (40255500)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. 久光隆 (50327946)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. 西谷友重 (50393244)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 岩田裕子 (80171908)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 渡邉裕介 (20562333)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
8. KONISHI Noboru (20145832)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. HAYASHI Tamaki (50351648)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
10. 片山由美 (20570675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. 深山俊治 (60779304)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 瀬谷大貴 (30806021)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 田中亨 (50806065)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SAKABE Masahide 坂部 正英

Research Projects

Research Products

Co-Researchers

Novel approaches to analyze the regulatory mechanisms of cardiovascular genes in development and morphogenesis

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Signaling pathways that regulate cardiovascular development and morphogenesis

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心臓中隔や弁の前駆組織をつくりだす部位特異的な細胞運動とそれを誘導するメカニズムPrincipal Investigator

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心臓形態形成を制御する新規シグナル伝達ネットワークの解明とその意義Principal Investigator

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Regulation of vascular endothelial cells by signaling molecules

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Significance of a new endothelial gene TMEM100 in vascular development and disease

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Transcriptional regulation of cardiovascular development

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New Transgenic Mouse System to Analyze Functional Mechanisms of Transcription Factors

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Roles of ununiform cellular signaling during cardiac morphogenesisPrincipal Investigator

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Investigation of the mechanisms of congenital heart defects using developmental engineering.Principal Investigator

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Significance of novel protein kinase in muscle function and disease

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[Book] TMEM100, a novel intracellular transmembrane protein essential for cardiovascular development. In Etiology and morphogenesis of congenital heart disease. Ed. by Srivastava D, Keller BB, Markwald R, Yamagishi H, Nakanishi T.2017

Author(s)

Publisher

Data Source

[Book] TMEM100, a novel intracellular transmembrane protein essential for cardiovascular development. In Etiology and morphogenesis of congenital heart disease. Ed. by Srivastava D, Keller BB, Markwald R, Yamagishi H, Nakanishi T.2017

Author(s)

Publisher

Data Source

[Book] Roles of endothelial Hrt genes for vascular development. In Etiology and morphogenesis of congenital heart disease. Ed. by Srivastava D, Keller BB, Markwald R, Yamagishi H, Nakanishi T.2017

Author(s)

SAKABE Masahide 坂部正英