Kumei Shima 粂井志麻

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KUMEI Shima 粂井志麻

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Researcher Number	00548969
Affiliation (based on the past Project Information) *help	2016 – 2020: 旭川医科大学, 大学病院, 医員 2014 – 2015: 旭川医科大学, 大学病院, その他 2012: 旭川医科大学, 大学病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology Except Principal Investigator Gastroenterology
Keywords	Principal Investigator 内臓痛覚過敏 / 腸内細菌 / 過敏性腸症候群 / プロスタグランジン / 慢性炎症 / 脳腸相関 / 短鎖脂肪酸 / 1-methylnicotinamide / 鬱様行動 / 1-MNA … More / CRF / 消化器内科 / IP作動薬 / プロスタグランジンI２ / 内臓痛覚閾値 / メタボローム解析 … More Except Principal Investigator 直腸伸展刺激 / 過敏性腸症候群 / ラット / カンナビノイド / アデノシン / ドパミン / 中枢神経 / オレキシン / 内臓知覚 / がん細胞増殖 / 血管新生 / VEGF / cancer / PPARgamma Less

脳腸相関におけるプロスタグランジンI2の役割解明と新規IBS治療薬への挑戦Principal Investigator
- Principal Investigator
  
  粂井志麻
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Asahikawa Medical College
Roles of prostaglandin I2 in gastrointestinal functioning in irritable bowel syndromePrincipal Investigator
- Principal Investigator
  
  Kumei Shima
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Asahikawa Medical College
Role of brain orexin in the pathogenesis of irritable bowel syndrome
- Principal Investigator
  
  Toshikatsu Okumura
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Asahikawa Medical College
Anti-tumor action by PPARgamma ligands in pancreatic cancer: analysis of angigenesis-related genes expression
- Principal Investigator
  
  OKUMURA Toshikatsu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Asahikawa Medical College

All 2020 2019 2018 2016 2015 2010

All Journal Article

[Journal Article] Brain orexin improves intestinal barrier function via the vagal cholinergic pathway2020
- Author(s)
  Okumura Toshikatsu、Nozu Tsukasa、Ishioh Masatomo、Igarashi Sho、Kumei Shima、Ohhira Masumi
- Journal Title
  
  Neuroscience Letters
  
  Volume: 714 Pages: 134592-134592
- DOI
  10.1016/j.neulet.2019.134592
- Open Access
- Data Source
  KAKENHI-PROJECT-19K08410, KAKENHI-PROJECT-18K15739
[Journal Article] Central oxytocin signaling mediates the central orexin-induced visceral antinociception through the opioid system in conscious rats2019
- Author(s)
  Okumura Toshikatsu、Nozu Tsukasa、Kumei Shima、Ohhira Masumi
- Journal Title
  
  Physiology & Behavior
  
  Volume: 198 Pages: 96-101
- DOI
  10.1016/j.physbeh.2018.10.007
- Data Source
  KAKENHI-PROJECT-18K15739
[Journal Article] Prostaglandin F2α Facilitates Platelet Activation by Acting on Prostaglandin E2 Receptor Subtype EP3 and Thromboxane A2 Receptor TP in Mice2019
- Author(s)
  Kashiwagi Hitoshi、Yuhki Koh-ichi、Imamichi Yoshitaka、Kojima Fumiaki、Kumei Shima、Tasaki Yoshikazu、Narumiya Shuh、Ushikubi Fumitaka
- Journal Title
  
  Thrombosis and Haemostasis
  
  Volume: 119 Issue: 08 Pages: 1311-1320
- DOI
  10.1055/s-0039-1688906
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08604, KAKENHI-PROJECT-17K11214, KAKENHI-PROJECT-18K15739
[Journal Article] Ghrelin acts centrally to induce an antinociceptive action during colonic distension through the orexinergic, dopaminergic and opioid systems in conscious rats.2018
- Author(s)
  Okumura T, Nozu T, Kumei S, Takakusaki K, Ohhira M.
- Journal Title
  
  Brain Res.
  
  Volume: 1686 Pages: 48-54
- Data Source
  KAKENHI-PROJECT-26460955
[Journal Article] Levodopa acts centrally to induce an antinociceptive action against colonic distension through activation of D2 dopamine receptors and the orexinergic system in the brain in conscious rats.2016
- Author(s)
  2.Okumura T, Nozu T, Kumei S, Takakusaki K, Miyagishi S, Ohhira M
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 130(2): Pages: 123-127
- NAID
  120005763350
- Data Source
  KAKENHI-PROJECT-26460955
[Journal Article] Adenosine A1 receptors mediate the intracisternal injection of orexin-induced antinociceptive action against colonic distension in conscious rats.2016
- Author(s)
  1.Okumura T, Nozu T, Kumei S, Takakusaki K, Miyagishi S, Ohhira M.
- Journal Title
  
  J Neurol Sci.
  
  Volume: 362 Pages: 106-110
- Data Source
  KAKENHI-PROJECT-26460955
[Journal Article] Antinociceptive action against colonic distension by brain orexin in conscious rats2015
- Author(s)
  Okumura T, Nozu T, Kumei S, Takakusaki K, Miyagishi S, Ohhira M
- Journal Title
  
  Brain Research
  
  Volume: 1598 Pages: 12-17
- DOI
  10.1016/j.brainres.2014.12.021
- NAID
  120005712587
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25290001, KAKENHI-PLANNED-26120004, KAKENHI-PROJECT-26460955
[Journal Article] Thiazolidinediones enhance vascular endothelial growth factor expression and induce cell growth inhibition in non-small-cell lung cancer cells2010
- Author(s)
  Yoshizaki T, Motomura W, Tanno S, Kumei S, Yoshizaki Y, Tanno S, Okumura T
- Journal Title
  
  J Exp Clin Cancer Res
  
  Volume: 29 Pages: 22-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590753

1. OKUMURA Toshikatsu (60281903)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
2. NOZU Tsukasa (30312367)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. 高草木薫 (10206732)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. KOJIMA Fumiaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kumei Shima 粂井 志麻

KUMEI Shima 粂井 志麻

Research Projects

Research Products

Co-Researchers

脳腸相関におけるプロスタグランジンI2の役割解明と新規IBS治療薬への挑戦Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Roles of prostaglandin I2 in gastrointestinal functioning in irritable bowel syndromePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of brain orexin in the pathogenesis of irritable bowel syndrome

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Anti-tumor action by PPARgamma ligands in pancreatic cancer: analysis of angigenesis-related genes expression

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Brain orexin improves intestinal barrier function via the vagal cholinergic pathway2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Central oxytocin signaling mediates the central orexin-induced visceral antinociception through the opioid system in conscious rats2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prostaglandin F2α Facilitates Platelet Activation by Acting on Prostaglandin E2 Receptor Subtype EP3 and Thromboxane A2 Receptor TP in Mice2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ghrelin acts centrally to induce an antinociceptive action during colonic distension through the orexinergic, dopaminergic and opioid systems in conscious rats.2018

Author(s)

Journal Title

Data Source

[Journal Article] Levodopa acts centrally to induce an antinociceptive action against colonic distension through activation of D2 dopamine receptors and the orexinergic system in the brain in conscious rats.2016

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Adenosine A1 receptors mediate the intracisternal injection of orexin-induced antinociceptive action against colonic distension in conscious rats.2016

Author(s)

Journal Title

Data Source

[Journal Article] Antinociceptive action against colonic distension by brain orexin in conscious rats2015

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Thiazolidinediones enhance vascular endothelial growth factor expression and induce cell growth inhibition in non-small-cell lung cancer cells2010

Author(s)

Journal Title

Data Source

Kumei Shima 粂井志麻

KUMEI Shima 粂井志麻