Takahashi Masaki 高橋理貴

… Alternative Names

TAKAHASHI MASAKI 高橋理貴

TAKAHASHI Masaki 高橋理貴

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Researcher Number	00549529
Other IDs
Affiliation (based on the past Project Information) *help	2020 – 2023: 東京大学, 医科学研究所, 特任准教授 2017 – 2018: 東京大学, 医科学研究所, 特任准教授 2015: 東京大学, 医科学研究所, 特任准教授 2014: 東京大学, 医科学研究所, 特任助教 2013: 独立行政法人国立精神・神経医療研究センター, 神経研究所神経薬理研究部, 科研費研究員 … More 2010: 独立行政法人国立精神・神経医療研究センター, 神経研究所・神経薬理研究部, 流動研究員 2010: 独立行政法人国立精神・神経医療研究センター, 神経研究所神経薬理研究部, 流動研究員 2009: National Center of Neurology and Psychiatry, 神経研究所遺伝子工学研究部, 流動研究員 Less
Review Section/Research Field	Principal Investigator Medium-sized Section 90:Biomedical engineering and related fields / Biomedical engineering and related fields / Nerve anatomy/Neuropathology / General medical chemistry
Keywords	Principal Investigator RNAアプタマー / アプタマー / ウイルス / ウイルス様粒子 / インスリンン受容体 / 量子ドット / DDS / 脳 / 薬剤送達 / VLP … More / 機能性核酸 / デングウイルス / ウイルス感染症 / キメラ核酸 / siRNA / 生物・生体工学 / 核酸 / GPCR / virus-like particle / 膜タンパク質 / Huntington's disease / ノンコーディングRNA / microRNA / R6/2マウス / 凝集体形成 / ハンチントン病 / 神経変性疾患 / non-coding RNA / トリプレットリピート病 / 対立遺伝子 / 脳神経疾患 / SNP / RNAi治療 / 発現制御 Less

Development of visualized nano-DDS agents targeting brain by RNA aptamers and quantum dotsPrincipal Investigator
- Principal Investigator
  
  Takahashi Masaki
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokyo
Development of multi-functional siRNA-aptamer chimera for virus infectionsPrincipal Investigator
- Principal Investigator
  
  Takahashi Masaki
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokyo
Development of RNA aptamer against membrane protein using virus-like particlePrincipal Investigator
- Principal Investigator
  
  TAKAHASHI MASAKI
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Biomedical engineering and related fields
- Research Institution
  The University of Tokyo
An analysis of relation between MENb and nuclear foci in Huntington's diseasePrincipal Investigator
- Principal Investigator
  
  Takahashi Masaki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  The University of Tokyo
  独立行政法人国立精神・神経医療研究センター
Establishment of tailor-made RNAi knockdown technique against triplet repeat disease-causing allelesPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Masaki
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  General medical chemistry
- Research Institution
  National Center of Neurology and Psychiatry

All 2023 2022 2021 2020 2018 2015 2014 2013 2011 2010 2009 Other

All Journal Article Presentation Book Patent

[Book] トリプレット・リピート病原因遺伝子に対するテーラーメイドRNAiノックダウン.(29)2011
- Author(s)
  高橋理貴、北條浩彦
- Publisher
  「mTOR シグナル」実験医学
- Data Source
  KAKENHI-PROJECT-21890312
[Book] 実験医学(「mTORシグナル」 : トリプレットリピート病原因遺伝子に対するテーラーメイドRNAiノックダウン)2011
- Author(s)
  高橋理貴、北條浩彦
- Total Pages
  4
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-21890312
[Journal Article] Anti-TGF-β1 aptamer enhances therapeutic effect of tyrosine kinase inhibitor, gefitinib, on non-small cell lung cancer in xenograft model2022
- Author(s)
  Takahashi Masaki、Hashimoto Yoshifumi、Nakamura Yoshikazu
- Journal Title
  
  Molecular Therapy - Nucleic Acids
  
  Volume: 29 Pages: 969-978
- DOI
  10.1016/j.omtn.2022.06.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19909
[Journal Article] Nucleic acid ligands act as a PAM and agonist depending on the intrinsic ligand binding state of P2RY22021
- Author(s)
  Takahashi Masaki、Amano Ryo、Ozawa Michiru、Martinez Anna、Akita Kazumasa、Nakamura Yoshikazu
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 118 Issue: 18
- DOI
  10.1073/pnas.2019497118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21880, KAKENHI-PROJECT-20K15406
[Journal Article] Single-round isolation of diverse RNA aptamers from a random sequence pool2018
- Author(s)
  Imashimizu M, Takahashi M, Amano R, Nakamura Y
- Journal Title
  
  Biology Methods & Protocols
  
  Volume: 3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K20087
[Journal Article] Aptamers targeting cell surface proteins2018
- Author(s)
  Takahashi Masaki
- Journal Title
  
  Biochimie
  
  Volume: 145 Pages: 63-72
- DOI
  10.1016/j.biochi.2017.11.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K20087
[Journal Article] Supplemental Treatment for Huntington’s Disease with miR-132 that Is Deficient in Huntington’s Disease Brain2018
- Author(s)
  Fukuoka Masashi、Takahashi Masaki、Fujita Hiromi、Chiyo Tomoko、Popiel H. Akiko、Watanabe Shoko、Furuya Hirokazu、Murata Miho、Wada Keiji、Okada Takashi、Nagai Yoshitaka、Hohjoh Hirohiko
- Journal Title
  
  Mol. Ther. Nucleic Acids
  
  Volume: 11 Pages: 79-90
- DOI
  10.1016/j.omtn.2018.01.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19658, KAKENHI-PROJECT-16K19003, KAKENHI-PROJECT-16K15093, KAKENHI-PROJECT-17K20087, KAKENHI-PUBLICLY-17H05699, KAKENHI-PROJECT-16H05325
[Journal Article] Normalization of overexpressed alpha-synuclein causing Parkinson’s disease by a moderate gene silencing with RNA interference.2015
- Author(s)
  Takahashi M., Suzuki M., Fukuoka M., Fujikake N., Watanabe S., Murata M., Wada K., Nagai Y., and *Hohjoh H.
- Journal Title
  
  Mol Ther Nucleic Acids
  
  Volume: 4 Pages: e241-e241
- DOI
  10.1038/mtna.2015.14
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390226, KAKENHI-PROJECT-15K19502, KAKENHI-PROJECT-25670428, KAKENHI-PROJECT-26670446, KAKENHI-PROJECT-25871169
[Journal Article] A novel measurement of allele discrimination for assessment of allele-specific silencing by RNA interference.2014
- Author(s)
  Takahashi M. and *Hohjoh H.
- Journal Title
  
  Mol Biol Rep
  
  Volume: 41 Issue: 11 Pages: 7115-7120
- DOI
  10.1007/s11033-014-3586-7
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390226, KAKENHI-PROJECT-25670428, KAKENHI-PROJECT-25871169
[Journal Article] A functional involvement of ABCE1, eukaryotic ribosome recycling factor, in nonstop mRNA decay in Drosophila melanogaster cells2014
- Author(s)
  (206)Kashima, I., Takahashi, M., Hashimoto, Y., Sakota, E., Nakamura, Y., Inada, T.
- Journal Title
  
  Biochimie
  
  Volume: 106 Pages: 10-16
- DOI
  10.1016/j.biochi.2014.08.001
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24241074, KAKENHI-PROJECT-25871169, KAKENHI-PROJECT-26840001
[Journal Article] Gene silencing mediated by endogenous microRNAs under heat stress conditions in mammalian cells.2014
- Author(s)
  Fukuoka M., Yoshida M., Eda A., Takahashi M., *Hohjoh H.
- Journal Title
  
  PLoS ONE
  
  Volume: 9(7) Issue: 7 Pages: e103130-e103130
- DOI
  10.1371/journal.pone.0103130
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390226, KAKENHI-PROJECT-25670428, KAKENHI-PROJECT-25871169
[Journal Article] Thyroid hormone-dependent development of the GABAergic pre- and post-synaptic components in the rat hippocampus.2013
- Author(s)
  Sawano E, Takahashi M, Negishi T, Tashiro T.
- Journal Title
  
  Int J Dev Neurosci
  
  Volume: 31 Issue: 8 Pages: 751-61
- DOI
  10.1016/j.ijdevneu.2013.09.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23681010, KAKENHI-PROJECT-25871169
[Journal Article] Specific inhibition of tumor cells by oncogenic EGFR specific silencing by RNA interference.2013
- Author(s)
  Takahashi M., Chiyo T., Okada T., and *Hohjoh H.
- Journal Title
  
  PLoS ONE
  
  Volume: 8（８） Issue: 8 Pages: e73214-e73214
- DOI
  10.1371/journal.pone.0073214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390226, KAKENHI-PROJECT-25670428, KAKENHI-PROJECT-25871169
[Journal Article] Ubiquitin C-terminal hydrolase L1 (UCH-L1) act as a novel potentiator of cyclin-dependent kinases to enhance cell proliferation, independent of its hydrolase activity2013
- Author(s)
  Kabuta, T., Mitsui, T., Takahashi, M., Fujiwara, Y., Kabuta, C., Konya, C., Tsuchiya, Y., Hatanaka, Y., Uchida, K., Hohjoh, H., Wada, K
- Journal Title
  
  J. Biol. Chem
  
  Volume: 288 Issue: 18 Pages: 12615-12626
- DOI
  10.1074/jbc.m112.435701
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650199, KAKENHI-PROJECT-24390226, KAKENHI-PROJECT-24680038, KAKENHI-PROJECT-25670428, KAKENHI-PROJECT-25871169
[Journal Article] Tailor-made RNAi knockdown against triplet repeat disease-causing alleles2010
- Author(s)
  Takahashi M, Watanabe S, Murata M, Furuya H, Kanazawa I, Wada K, Hohjoh H
- Journal Title
  
  Proc Natl Acad Sci USA.
  
  Volume: 107 Pages: 21731-21736
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890312
[Journal Article] Tailor-made RNAi knockdown against triplet repeat disease-causing alleles2010
- Author(s)
  Takahashi M, Watanabe S, Murata M, Furuya H, Kanazawa I, Wada K, Hohjoh H
- Journal Title
  
  Proc Natl Acad Sci USA. 107(50)
  
  Pages: 21731-21736
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890312
[Patent] アデノ随伴ウイルスセロタイプ９に対するアプタマー及びその使用2023
- Inventor(s)
  高橋理貴、天野亮、中村義一
- Industrial Property Rights Holder
  高橋理貴、天野亮、中村義一
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2024-040542
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-22K19909
[Patent] シナプス形成増強剤及び神経変性疾患治療剤2015
- Inventor(s)
  北條浩彦、高橋理貴
- Industrial Property Rights Holder
  独立行政法人国立精神・神経医療研究センター
- Industrial Property Rights Type
  特許
- Filing Date
  2015-12-21
- Data Source
  KAKENHI-PROJECT-25871169
[Patent] 優性アレル発現抑制剤2010
- Inventor(s)
  北條浩彦、高橋理貴
- Industrial Property Rights Holder
  独立行政法人国立精神・神経医療研究センター
- Industrial Property Number
  2010-139925
- Filing Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-21890312
[Patent] 優性変異遺伝子発現抑制剤2010
- Inventor(s)
  北條浩彦、高橋理貴
- Industrial Property Rights Holder
  独立行政法人国立精神・神経医療研究センター
- Industrial Property Number
  2010-222847
- Filing Date
  2010-09-30
- Data Source
  KAKENHI-PROJECT-21890312
[Patent] 長鎖繰返し配列を含有する遺伝子又は遺伝子産物の選択的又は優先的回収方法2009
- Inventor(s)
  北條浩彦、高橋理貴
- Industrial Property Rights Holder
  独立行政法人国立精神・神経医療研究センター
- Industrial Property Number
  2009-283653
- Filing Date
  2009-12-15
- Data Source
  KAKENHI-PROJECT-21890312
[Presentation] チクングニアウイルス侵入抑制RNAアプタマー性状解析2023
- Author(s)
  後藤覚、天野亮、浜田道昭、中村義一、高橋理貴
- Organizer
  第70回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19909
[Presentation] VLP-SELEX generates virus-neutralizing aptamers2023
- Author(s)
  Masaki Takahashi, Ryo Amano, Kaku Goto, Akiya Michishita, Akiko Ichinose, Kazumi Haga, Meng Ling Moi, Michiaki Hamada, Yoshikazu Nakamura
- Organizer
  第8回日本核酸医薬学会年会
- Data Source
  KAKENHI-PROJECT-22K19909
[Presentation] Generation of an RNA aptamer neutralizing dengue viruses by SELEX method targeting virus-like particles and advanced in silico analyses2023
- Author(s)
  Ryo Amano, Akiya Michishita, Ryota Nakano, Akiko Ichinose, Kazumi Haga, Meng Ling Moi, Michiaki Hamada, Yoshikazu Nakamura, Masaki Takahashi
- Organizer
  第50回国際核酸化学シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19909
[Presentation] Generation of virus-neutralizing aptamers by VLP-SELEX2023
- Author(s)
  Masaki Takahashi, Ryo Amano, Kaku Goto, Akiya Michishita, Akiko Ichinose, Kazumi Haga, Meng Ling Moi, Michiaki Hamada, Yoshikazu Nakamura
- Organizer
  第24回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-22K19909
[Presentation] VLP-SELEXとin silico解析によるデングウイルス中和アプタマーの創製と有効性評価2023
- Author(s)
  天野亮、道下瑛陽、中野涼太、一ノ瀬顕子、芳賀和美、Meng Ling Moi、浜田道昭、中村義一、高橋理貴
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K19909
[Presentation] チクングニアウイルス中和RNAアプタマー作用機序解析2023
- Author(s)
  後藤覚、天野亮、一ノ瀬顕子、道下瑛陽、浜田道昭、中村義一、高橋理貴
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K19909
[Presentation] VLPを利用したMulti-target SELEXとin silico解析によるデングウイルス中和アプタマーの創製2022
- Author(s)
  天野亮、一ノ瀬顕子、浜田道昭、中村義一、高橋理貴
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K21880
[Presentation] 膜タンパク質GPCRに対するアプタマー創製法「VLP-SELEX法」の開発2022
- Author(s)
  高橋理貴
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K21880
[Presentation] チクングニアウイルス様粒子標的RNAアプタマー2022
- Author(s)
  後藤覚、天野亮、中村義一、高橋理貴
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K21880
[Presentation] ウイルス様粒子とin silico解析を用いたデングウイルス中和アプタマーの創製2020
- Author(s)
  天野亮、一ノ瀬顕子、浜田道昭、中村義一、高橋理貴
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K21880
[Presentation] ウイルス様粒子を用いたGPCRアプタマー創製法の開発2018
- Author(s)
  高橋理貴、天野亮、Anna Martinez、秋田一雅、中村義一
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K20087
[Presentation] Generation of aptamers against GPCR by a novel SELEX employing virus-like particles (VLPs)2018
- Author(s)
  Masaki Takahashi, Ryo Amano, Anna Martinez, Kazumasa Akita, Yoshikazu Nakamura
- Organizer
  The Oligonucleotide Therapeutics Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20087
[Presentation] ウイルス様粒子を用いたGPCR結合RNAアプタマーの創製2018
- Author(s)
  天野亮、高橋理貴、Anna Martinez、秋田一雅、中村義一
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K20087
[Presentation] ミセル化GPCRを標的としたSELEX手法の開発2018
- Author(s)
  Maritinez Anna、秋田一雅、今井博貴、猪股恵美礼、高橋理貴、天野亮、中村義一
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K20087
[Presentation] Development of an efficient Cell-SELEX to generate RNA aptamers against a cell surface protein of interest2015
- Author(s)
  Masaki Takahashi, Yoshifumi Hashimoto, Eri Sakota, Yoshikazu Nakamura
- Organizer
  The Oligonucleotide Therapeutics Society 11th Annual Meeting
- Place of Presentation
  Stadspodia, Leiden, Netherlands
- Year and Date
  2015-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25871169
[Presentation] A corrective gene silencing by RNA interference to control over-expressed SNCA2013
- Author(s)
  Takahashi M, Suzuki M, Fujikake N, Murata M, Wada K, Nagai Y, Hohjoh H:
- Organizer
  The American Society of Human Genetics (ASHG) 63rd anneual meeting
- Place of Presentation
  USA, Boston, Boston Convention & Exhibition Center
- Data Source
  KAKENHI-PROJECT-25871169
[Presentation] 野生型α―シヌクレイン過剰発現に対する遺伝子発現補正型RNAi誘導法の確立と有効性評価2013
- Author(s)
  高橋理貴、鈴木マリ、藤掛伸宏、村田美穂、和田圭司、永井義隆、北條浩彦
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  兵庫県、神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-25871169
[Presentation] Construction of Drug Screening System and Allele-Specific Silencing Against Pathogenic ALK2 Mutants in Pluripotent Stem Cell (iPSC) of Fibrodysplasia Ossificans2013
- Author(s)
  Furuya H, Takahashi M, Hohjoh H, Era T
- Organizer
  42nd Annual Meeting of the Child-Neurology-Society
- Place of Presentation
  USA, Texas, Austin Hilton Hotel
- Data Source
  KAKENHI-PROJECT-25871169
[Presentation] Identification of triplet repeat disease-causing alleles by a novel pull-down method and disease-causing allele-specific silencing by RNAi2010
- Author(s)
  高橋理貴, 渡邉荘子, 村田美穂, 古谷博和, 金澤一郎, 和田圭司, 北條浩彦
- Organizer
  ASHG
- Place of Presentation
  ワシントンコンベンションセンター
- Data Source
  KAKENHI-PROJECT-21890312
[Presentation] 新規プルダウン法を用いたリピート病原因対立遺伝子の優先的回収法とSNPを指標とした病因対立遺伝子の特異的RNAiノックダウン2010
- Author(s)
  高橋理貴、渡邉荘子、村田美穂、古谷博和、金澤一郎、和田圭司、北條浩彦
- Organizer
  分子生物学会
- Place of Presentation
  兵庫県神戸国際会議場
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21890312
[Presentation] Identification of triplet repeat disease-causing alleles by a novel pull-down method and disease-causing allele-specific silencing by RNAi2010
- Author(s)
  Takahashi M, Watanabe S, Murata M, Furuya H, Kanazawa I, Wada K, Hohjoh H
- Organizer
  ASHG(American Society of Human Genetics)
- Place of Presentation
  アメリカワシントンDCワシントンコンベンションセンター
- Year and Date
  2010-11-03
- Data Source
  KAKENHI-PROJECT-21890312
[Presentation] 新規プルダウン法を用いたリピート病原因対立遺伝子の優先的回収法とSNPを指標とした病因対立遺伝子の特異的RNAiノックダウン2010
- Author(s)
  高橋理貴、渡邉荘子、村田美穂、古谷博和、金澤一郎、和田圭司、北條浩彦
- Organizer
  分子生物学会
- Place of Presentation
  神戸国際展示場
- Data Source
  KAKENHI-PROJECT-21890312
[Presentation] Application of atypical RNAi for human diseases
- Author(s)
  Takahashi M, Nakamura Y, Hohjoh H
- Organizer
  Joint Australia and Japan RNA (jajRNA) meeting
- Place of Presentation
  Sydeny, Australia
- Year and Date
  2014-11-02 – 2014-11-05
- Data Source
  KAKENHI-PROJECT-25871169
[Presentation] Gene silencing mediated by endogenous miRNAs under heat stress conditions in mammalian cells
- Author(s)
  Fukuoka M, Yoshida M, Eda A, Takahashi M, Hohjoh H
- Organizer
  The American Society of Human Genetics (ASHG) 64th annual meeting
- Place of Presentation
  San Diego, USA
- Year and Date
  2014-10-18 – 2014-10-22
- Data Source
  KAKENHI-PROJECT-25871169
[Presentation] Early drug responses that are followed by an acquired drug resistance in non-small cell lung cancer cells exposed to gefitinib
- Author(s)
  Takahashi M, Fukuoka M, Hohjoh H
- Organizer
  The American Society of Human Genetics (ASHG) 64th annual meeting
- Place of Presentation
  San Diego, USA
- Year and Date
  2014-10-18 – 2014-10-22
- Data Source
  KAKENHI-PROJECT-25871169

1. 根岸隆之

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# of Collaborated Products: 1 results
2. 北条浩彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
3. 中村義一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 永井義隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. 和田圭司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takahashi Masaki 高橋 理貴

TAKAHASHI MASAKI 高橋 理貴

TAKAHASHI Masaki 高橋 理貴

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Development of visualized nano-DDS agents targeting brain by RNA aptamers and quantum dotsPrincipal Investigator

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Development of multi-functional siRNA-aptamer chimera for virus infectionsPrincipal Investigator

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Development of RNA aptamer against membrane protein using virus-like particlePrincipal Investigator

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An analysis of relation between MENb and nuclear foci in Huntington's diseasePrincipal Investigator

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Establishment of tailor-made RNAi knockdown technique against triplet repeat disease-causing allelesPrincipal Investigator

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[Book] トリプレット・リピート病原因遺伝子に対するテーラーメイドRNAiノックダウン.(29)2011

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[Book] 実験医学(「mTORシグナル」 : トリプレットリピート病原因遺伝子に対するテーラーメイドRNAiノックダウン)2011

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[Journal Article] Anti-TGF-β1 aptamer enhances therapeutic effect of tyrosine kinase inhibitor, gefitinib, on non-small cell lung cancer in xenograft model2022

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[Journal Article] Nucleic acid ligands act as a PAM and agonist depending on the intrinsic ligand binding state of P2RY22021

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[Journal Article] Single-round isolation of diverse RNA aptamers from a random sequence pool2018

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[Journal Article] Aptamers targeting cell surface proteins2018

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[Journal Article] Supplemental Treatment for Huntington’s Disease with miR-132 that Is Deficient in Huntington’s Disease Brain2018

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[Journal Article] Normalization of overexpressed alpha-synuclein causing Parkinson’s disease by a moderate gene silencing with RNA interference.2015

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[Journal Article] A novel measurement of allele discrimination for assessment of allele-specific silencing by RNA interference.2014

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[Journal Article] A functional involvement of ABCE1, eukaryotic ribosome recycling factor, in nonstop mRNA decay in Drosophila melanogaster cells2014

Takahashi Masaki 高橋理貴

TAKAHASHI MASAKI 高橋理貴

TAKAHASHI Masaki 高橋理貴