Kato Takuya 加藤琢哉

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KATO Takuya 加藤琢哉

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Researcher Number	00551970
Other IDs
Affiliation (Current)	2025: 藤田医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 北里大学, 医学部, 講師 2018 – 2021: 北里大学, 医学部, 助教 2015: 名古屋大学, 医学(系)研究科(研究院), 助教 2015: 名古屋大学, 大学院医学系研究科, 特任助教 2013 – 2014: 名古屋大学, 医学(系)研究科(研究院), 特任助教 … More 2012 – 2013: 名古屋大学, 医学系研究科, 助教 2011 – 2013: 名古屋大学, 医学(系)研究科(研究院), 助教 2010: Nagoya University, 医学系研究科, 助教 2009: Nagoya University, 大学院・医学系研究科, 助教 Less
Review Section/Research Field	Principal Investigator Basic Section 49030:Experimental pathology-related / 0803:Pathology, infection/immunology, and related fields / Tumor biology / Tumor biology / Experimental pathology Except Principal Investigator Tumor biology / Tumor biology
Keywords	Principal Investigator RFP / 浸潤 / Connexin 43 / 細胞競合 / CAF / 膵癌 / 集団的浸潤 / 形態形成 / 癌細胞浸潤 / SUMO化 … More / p53 / USP7 / integrin / MRTF / Collective migration / がん / collective invasion / 蛋白分解 / Ubiquitin / Lamin A … More Except Principal Investigator TRIM27 / マイクロRNA124 / インテグリンベータ１ / MRTFB / がんの集団的移動 / 細胞接着分子 / N-Cadherin / 神経芽細胞 / N-カドヘリン / インテグリン / Girdin / MTRF-B / 細胞接着因子 / 集団的移動 / がん細胞 / ユビキチン化 / 神経膠芽腫 / RFP / 卵巣がん / 抗がん剤耐性 / RET finger protein / HDAC1 Less

Connexin 43 dependent mechanism for elimination of cancer cells from epithelial layerPrincipal Investigator
- Principal Investigator
  
  加藤琢哉
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Kitasato University
Mechanism for pancreatic cancer cell survival against restraining CAFsPrincipal Investigator
- Principal Investigator
  
  Kato Takuya
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Kitasato University
Mechanism of determining the invasive pattern of SCCPrincipal Investigator
- Principal Investigator
  
  Kato Takuya
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0803:Pathology, infection/immunology, and related fields
- Research Institution
  Kitasato University
Molecular Mechanisms of Collective Migration of Cancer Cells
- Principal Investigator
  
  Takahashi Masahide
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  Nagoya University
Regulatory mechanism of p53 deubiquitinating enzyme USP7Principal Investigator
- Principal Investigator
  
  KATO Takuya
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Nagoya University
Mechanism of chemoresistance by HDAC1-associating protein and development of molecular targeted therapy
- Principal Investigator
  
  TAKAHASHI Masahide
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  Nagoya University
Molecular mechanism for collective invasion of cancer cell groupsPrincipal Investigator
- Principal Investigator
  
  KATO Takuya
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Nagoya University
Analysis of the regulatory mechanism of Lamin A degradation by RFP and its significance in malignant transformation.Principal Investigator
- Principal Investigator
  
  KATO Takuya
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Experimental pathology
- Research Institution
  Nagoya University

[Journal Article] REV7 is involved in outcomes of platinum-based chemotherapy in pancreatic cancer via controlling the DNA damage response2024
- Author(s)
  Akihiro Tamaki, Takuya Kato, Yasutaka Sakurai, Keita Sato, Kai Adachi, Masayoshi Tadehara, Taro Kogami, Masahiro Matsushita, Akiyoshi Hoshino, Itaru Sanoyama, Yoshiko Numata, Atsuko Umezawa, Masaaki Ichinoe, Masatoshi Ichihara, Chika Kusano, Yoshiki Murakumo
- Journal Title
  
  Cancer Science
  
  Volume: Volume115, Issue2 Issue: 2 Pages: 660-671
- DOI
  10.1111/cas.16044
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15414, KAKENHI-PROJECT-21K06894, KAKENHI-PROJECT-21K06973, KAKENHI-PROJECT-23K06486, KAKENHI-PROJECT-23K08306
[Journal Article] Interplay of adherens junctions and matrix proteolysis determines the invasive pattern and growth of squamous cell carcinoma2023
- Author(s)
  Kato Takuya、Jenkins Robert P、Derzsi Stefanie、Tozluoglu Melda、Rullan Antonio、Hooper Steven、Chaleil Rapha?l AG、Joyce Holly、Fu Xiao、Thavaraj Selvam、Bates Paul A、Sahai Erik
- Journal Title
  
  eLife
  
  Volume: 12
- DOI
  10.7554/elife.76520
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07450
[Journal Article] REV7 in Cancer Biology and Management2023
- Author(s)
  Yoshiki Murakumo, Yasutaka Sakurai, Takuya Kato, Hiroshi Hashimoto, Masaaki Ichinoe
- Journal Title
  
  Cancers (Basel) .
  
  Volume: 15 Issue: 6 Pages: 1-15
- DOI
  10.3390/cancers15061721
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06894, KAKENHI-PROJECT-21K06973, KAKENHI-PROJECT-20K07449, KAKENHI-PROJECT-20K07450
[Journal Article] Clinicopathological Significance of BRCAness in Resectable Pancreatic Ductal Adenocarcinoma and Its Association With Anticancer Drug Sensitivity in Pancreatic Cancer Cells2022
- Author(s)
  Tadehara Masayoshi、Kato Takuya、Adachi Kai、Tamaki Akihiro、Kesen Yurika、Sakurai Yasutaka、Ichinoe Masaaki、Koizumi Wasaburo、Murakumo Yoshiki
- Journal Title
  
  Pancreas
  
  Volume: 51 Issue: 2 Pages: 183-189
- DOI
  10.1097/mpa.0000000000001975
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16616, KAKENHI-PROJECT-20K07450, KAKENHI-PROJECT-21K06894, KAKENHI-PROJECT-21K06973
[Journal Article] Upregulation of REV7 correlates with progression of malignant melanoma2021
- Author(s)
  Hoshino Akiyoshi、Nakayama Chika、Jiang Shi‐Xu、Sakurai Yasutaka、Kato Takuya、Numata Yoshiko、Umezawa Atsuko、Ichinoe Masaaki、Murakumo Yoshiki
- Journal Title
  
  Pathology International
  
  Volume: 72 Issue: 1 Pages: 14-24
- DOI
  10.1111/pin.13174
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16616, KAKENHI-PROJECT-20K07450, KAKENHI-PROJECT-21K06894, KAKENHI-PROJECT-21K06973, KAKENHI-PROJECT-20K07449
[Journal Article] Increased expression of REV7 in small cell lung carcinomas and its association with tumor cell survival and proliferation2020
- Author(s)
  Sanoyama Itaru、Sakurai Yasutaka、Ichinoe Masaaki、Hoshino Akiyoshi、Kesen Yurika、Kato Takuya、Numata Yoshiko、Umezawa Atsuko、Jiang Shi‐Xu、Murakumo Yoshiki
- Journal Title
  
  Pathology International
  
  Volume: 71 Issue: 1 Pages: 15-23
- DOI
  10.1111/pin.13040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07450, KAKENHI-PROJECT-19K16616, KAKENHI-PROJECT-18H02643
[Journal Article] CAFs and Cancer Cells Co-Migration in 3D Spheroid Invasion Assay2020
- Author(s)
  Conti Sefora、Kato Takuya、Park Danielle、Sahai Erik、Trepat Xavier、Labernadie Anna
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 2179 Pages: 243-256
- DOI
  10.1007/978-1-0716-0779-4_19
- ISBN
  9781071607787, 9781071607794
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07450
[Journal Article] STING and IRF3 in stromal fibroblasts enable sensing of genomic stress in cancer cells to undermine oncolytic viral therapy2020
- Author(s)
  Arwert Esther N.、Milford Emma L.、Rullan Antonio、Derzsi Stefanie、Hooper Steven、Kato Takuya、Mansfield David、Melcher Alan、Harrington Kevin J.、Sahai Erik
- Journal Title
  
  Nature Cell Biology
  
  Volume: 22 Issue: 7 Pages: 758-766
- DOI
  10.1038/s41556-020-0527-7
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07450
[Journal Article] Potential involvement of kinesin-1 in the regulation of subcellular localization of Girdin2015
- Author(s)
  Aya Muramatsu, Atsushi Enomoto, Takuya Kato, Liang Weng, Keisuke Kuroda, Naoya Asai, Masato Asai, Shinji Mii, Masahide Takahashia
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 463 Issue: 4 Pages: 999-1005
- DOI
  10.1016/j.bbrc.2015.06.049
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06772, KAKENHI-PROJECT-15K08399, KAKENHI-PROJECT-15K21061, KAKENHI-PROJECT-25460493, KAKENHI-PROJECT-26640074, KAKENHI-PROJECT-25860293, KAKENHI-PROJECT-26221304
[Journal Article] Identification of the novel autoantigen candidate Rab GDP dissociation inhibitor alpha in isolated adrenocorticotropin deficiency2015
- Author(s)
  Kiyota A, Iwama S, Sugimura Y, Takeuchi S, Takagi H, Iwata N, Nakashima K, Suzuki H, Nishioka T, Kato T, Enomoto A, Arima H, Kaibuchi K, Oiso Y.
- Journal Title
  
  Endocr J
  
  Volume: 62 Issue: 2 Pages: 153-160
- DOI
  10.1507/endocrj.EJ14-0369
- NAID
  130004700287
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25830078, KAKENHI-PROJECT-221S0003
[Journal Article] Akt-girdin signaling in cancer-associated fibroblasts contributes to tumor progression2015
- Author(s)
  Yumiko Yamamura, Naoya Asai, Atsushi Enomoto, Takuya Kato, Shinji Mii, Yuji Kondo, Kaori Ushida, Kaoru Niimi, Nobuyuki Tsunoda, Masato Nagino, Shu Ichihara, Koichi Furukawa, Kengo Maeda, Toyoaki Murohara, Masahide Takahashi
- Journal Title
  
  Cancer Research
  
  Volume: 75 Issue: 5 Pages: 813-823
- DOI
  10.1158/0008-5472.can-14-1317
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22117005, KAKENHI-PROJECT-24390078, KAKENHI-PROJECT-24390095, KAKENHI-PROJECT-24689021, KAKENHI-PROJECT-25461124, KAKENHI-PROJECT-25670141, KAKENHI-PROJECT-25830078, KAKENHI-PROJECT-25860293, KAKENHI-PROJECT-15K15080, KAKENHI-PROJECT-26221304
[Journal Article] Regulation of cargo-selective endocytosis by dynamin 2 GTPase-activating protein girdin.2014
- Author(s)
  Liang Weng, Atsushi Enomoto, Hiroshi Miyoshi, Kiyofumi Takahashi, Naoya Asai, Nobuhiro Morone, Ping Jiang, Jian An, Takuya Kato, Keisuke Kuroda, Takashi Watanabe, Masato Asai, Maki Ishida-Takagishi, Yoshiki Murakumo, Hideki Nakashima, Kozo Kaibuchi and Masahide Takahashi.
- Journal Title
  
  EMBO Journal.
  
  Volume: 33 Issue: 18 Pages: 2098-2112
- DOI
  10.15252/embj.201488289
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J40134, KAKENHI-PLANNED-22117005, KAKENHI-PROJECT-24390095, KAKENHI-PROJECT-24689021, KAKENHI-PROJECT-25430118, KAKENHI-PROJECT-25830078, KAKENHI-PROJECT-26253024, KAKENHI-PROJECT-26286027, KAKENHI-PROJECT-26670188, KAKENHI-PROJECT-26860261, KAKENHI-PROJECT-26221304, KAKENHI-PROJECT-25460493
[Journal Article] TRIM27/MRTF-B-dependent integrinbeta1 expression defines leading cells in cancer cell collectives2014
- Author(s)
  Takuya Kato Atsushi Enomoto, Takashi Watanabe, Hisashi Haga, Sumire Ishida, Yuji Kondo, Koichi Furukawa, Takeshi Urano, Shinji Mii, Liang Weng, Maki Takagishi, Masato Asai, Naoya Asai, Kozo Kaibuchi, Yoshiki Murakumo, Masahide Takahashi
- Journal Title
  
  Cell Reports
  
  Volume: ―
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24650618
[Journal Article] Suppression of REV7 enhances cisplatin sensitivity in ovarian clear cell carcinoma cells.2014
- Author(s)
  Niimi K, Murakumo Y, Watanabe N, Kato T, Mii S, Enomoto A, Asai M, Asai N, Yamamoto E, Kajiyama H, Shibata K, Kikkawa F, Takahashi M.
- Journal Title
  
  Cancer Sci.
  
  Volume: 105 Issue: 5 Pages: 545-52
- DOI
  10.1111/cas.12390
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-24108008, KAKENHI-PROJECT-24590479, KAKENHI-PROJECT-24650618, KAKENHI-PROJECT-24689021, KAKENHI-PROJECT-25830078, KAKENHI-PROJECT-25860293, KAKENHI-PROJECT-25460493
[Journal Article] Detection of a Soluble Form of CD109 in Serum of CD109 Transgenic and Tumor Xenografted Mice.2014
- Author(s)
  Sakakura H, Murakumo Y, Mii S, Hagiwara S, Kato T, Asai M, Hoshino A, Yamamoto N, Sobue S, Ichihara M, Ueda M, Takahashi M.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 1 Pages: e83385-e83385
- DOI
  10.1371/journal.pone.0083385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590479, KAKENHI-PROJECT-24590768, KAKENHI-PROJECT-25830078, KAKENHI-PROJECT-25860293, KAKENHI-PROJECT-26870682, KAKENHI-PROJECT-25460493
[Journal Article] TRIM27/MTRF-B-dependent integrin beta1 expression defines leading cells in cancer cell collecitives2014
- Author(s)
  Kato, T., Enomoto, A., Watanabe, T., Haga, H., Ishida, S., Kondo, Y., Furukawa, K., Urano, T., Mii, S., Weng, L., Takagishi, M., Asai, M., Asai, N., Kaibuchi, K., Murakumo, Y. and Takahashi, M.
- Journal Title
  
  Cell Rep
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-24650618
[Journal Article] TRIM27/MRTF-B-Dependent Integrin β1 Expression Defines Leading Cells in Cancer Cell Collectives.2014
- Author(s)
  Takuya Kato, Atsushi Enomoto, Takashi Watanabe, Hisashi Haga, Sumire Ishida, Yuji Kondo, Koichi Furukawa, Takeshi Urano, Shinji Mii, Liang Weng, Maki Ishida-Takagishi, Masato Asai, Naoya Asai, Kozo Kaibuchi, Yoshiki Murakumo, Masahide Takahashi.
- Journal Title
  
  Cell reports.
  
  Volume: 7 Issue: 4 Pages: 1156-1167
- DOI
  10.1016/j.celrep.2014.03.068
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J40134, KAKENHI-PROJECT-24689021, KAKENHI-PROJECT-25830078, KAKENHI-PROJECT-25860293, KAKENHI-PROJECT-26640074, KAKENHI-PROJECT-26860261, KAKENHI-PROJECT-25460493
[Journal Article] Suppression of REV7 enhances cisplatin sensitivity in ovarian clear cell carcinoma cells2014
- Author(s)
  Niimi, K., Murakumo, Y., Watanabe, N., Kato, T., Mii, S., Enomoto, A., Asai, M., Asai, N., Yamamoto, E., Kajiyama, H., Shibata, K., Kikkawa, F., and Takahashi, M.
- Journal Title
  
  Cancer Sci
  
  Volume: 105 Pages: 545-552
- Data Source
  KAKENHI-PROJECT-24650618
[Journal Article] The REV7 subunit of DNA polymerase ζ is essential for primordial germ cell maintenance in the mouse.2013
- Author(s)
  Watanabe, N., Mii, S., Asai, N., Asai, M., Niimi, K., Ushida, K., Kato, T., Enomoto, A., Ishii, H., Takahashi, M., Murakumo, Y.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Issue: 15 Pages: 10459-10471
- DOI
  10.1074/jbc.m112.421966
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390199, KAKENHI-PROJECT-23651189, KAKENHI-PROJECT-24590479, KAKENHI-PROJECT-24689021, KAKENHI-PUBLICLY-25134711, KAKENHI-PROJECT-25830078, KAKENHI-PROJECT-25860293, KAKENHI-PROJECT-25460493
[Journal Article] Significance of cancer-associated fibroblasts in the regulation of gene expression in the leading cells of invasive lung cancer2013
- Author(s)
  An J, Enomoto A, Weng L, Kato T, Iwakoshi A, Ushida K, Maeda K, Ishida-Takagishi M, Ishii G, Ming S, Sun T, Takahashi M
- Journal Title
  
  J Cancer Res Clin Oncol
  
  Volume: 139(3) Pages: 379-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701051
[Journal Article] Metamorphosis of mesothelial cells with active horizontal motility in tissue culture2013
- Author(s)
  Nagai H, Chew SH, Okazaki Y, Funahashi S, Namba T, Kato T, Enomoto A, Jiang L, Akatsuka S, Toyokuni S
- Journal Title
  
  Sci Rep
  
  Volume: 3 Issue: 1 Pages: 1144-1144
- DOI
  10.1038/srep01144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701051, KAKENHI-PROJECT-23790440, KAKENHI-PLANNED-24108008, KAKENHI-PROJECT-24390094
[Journal Article] The Rev7 subunit of DNA polymeraseζis essential for primordial germ cell maintenance in the mouse2013
- Author(s)
  Watanabe, N., Mii, S., Asai, N., Asai, M., Niimi, K., Ushida, K., Kato, T., Enomoto, A., Ishii, H., Takahashi, M., and Murakumo, Y.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 288 Pages: 10459-10471
- Data Source
  KAKENHI-PROJECT-24650618
[Journal Article] Epidermal hyperplasia and appendage abnormalities in mice lacking CD1092012
- Author(s)
  Mii S, Murakumo Y, Asai N, Jijiwa M, Hagiwara S, Kato T, Asai M, Enomoto A, Ushida K, Sobue S, Ichihara M, Takahashi M
- Journal Title
  
  Am J Pathol
  
  Volume: 181(4) Pages: 1180-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701051
[Journal Article] Ret finger protein inhibits muscle differentiation by modulating serum response factor and enhancer of polycomb1.2012
- Author(s)
  Kee HJ, Kim JR, Joung H, Choe N, Lee SE, Eom GH, Kim JC, Geyer SH, Jijiwa M, Kato T, Kawai K, Weninger WJ, Seo SB, Nam KI, Jeong MH, Takahashi M, Kook H.
- Journal Title
  
  Cell Death Differentiation
  
  Volume: 19 Pages: 121-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701051
[Journal Article] RET finger protein expression is associated with prognosis in lung cancer with epidermal growth factor receptor mutations Pathol2012
- Author(s)
  Iwakoshi, A., Murakumo, Y., Kato, T., Kitamura, A., Mii, S., Saito, S., Yatabe, Y. and Takahashi. M.
- Journal Title
  
  Int
  
  Volume: 62 Pages: 324-330
- Data Source
  KAKENHI-PROJECT-24650618
[Journal Article] RET finger protein expression is associated with prognosis in lung cancer with epidermal growth factor receptor mutations2012
- Author(s)
  Iwakoshi A, Murakumo Y, Kato T, Kitamura A, Mii S, Saito S, Yatabe Y, Takahashi M
- Journal Title
  
  Pathol Int
  
  Volume: 62(5) Pages: 324-30
- NAID
  10031185208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701051
[Journal Article] Ret finger protein inhibits muscle differentiation by modulating serum response factor and enhancer of polycomb 12012
- Author(s)
  Kee, H. J., Kim, J-R, Joung, H., Choe, N., Lee, S. E., Eom, G. H., Kim, J. C., Geyer, S. H., Jijiwa, M., Kato, T., Kawai, K., Weninger, W. J., Seo, S. B., Nam, K-I., Jeong, M. H., Takahashi, M. and Kook, H.
- Journal Title
  
  Cell Death Differ
  
  Volume: 19 Pages: 121-131
- Data Source
  KAKENHI-PROJECT-24650618
[Journal Article] Expression of RET finger protein predicts chemoresistance in epithelial ovarian cancer2012
- Author(s)
  Horio, M., Kato, T., Mii, S., Enomoto, A., Asai, M., Asai, N., Murakumo, Y., Shibata, K., Kikkawa, F. and Takahashi, M.
- Journal Title
  
  Cancer Med
  
  Volume: 1 Pages: 218-229
- Data Source
  KAKENHI-PROJECT-24650618
[Journal Article] Involvement of Girdin in the determination of cell polarity during cell migration2012
- Author(s)
  Ohara K, Enomoto A, et al.
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 5 Pages: e36681-e36681
- DOI
  10.1371/journal.pone.0036681
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J56333, KAKENHI-PROJECT-20227006, KAKENHI-PROJECT-23249020, KAKENHI-PROJECT-23701051, KAKENHI-PROJECT-24390095, KAKENHI-PROJECT-24590479, KAKENHI-PROJECT-24689021, KAKENHI-PLANNED-22117005, KAKENHI-PUBLICLY-23122508
[Journal Article] The Dishevelled-associating protein Daple controls the non-canonical Wnt/Rac pathway and cell motility2012
- Author(s)
  Ishida-Takagishi M, Enomoto A, et al.
- Journal Title
  
  Nat Commun
  
  Volume: 3 Issue: 1 Pages: 859-859
- DOI
  10.1038/ncomms1861
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J56333, KAKENHI-PROJECT-20227006, KAKENHI-PROJECT-23249020, KAKENHI-PROJECT-23701051, KAKENHI-PROJECT-23790333, KAKENHI-PROJECT-24590479, KAKENHI-PLANNED-22117005, KAKENHI-PUBLICLY-23111511, KAKENHI-ORGANIZER-23112001, KAKENHI-PLANNED-23112004
[Journal Article] Expression of RET finger protein predicts chemoresistance in epithelial ovarian cancer2012
- Author(s)
  Horio M, Kato T, Mii S, Enomoto A, Asai M, Asai N, Murakumo Y, Shibata K, Kikkawa F, Takahashi M
- Journal Title
  
  Cancer Med
  
  Volume: 1(2) Pages: 218-29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701051
[Journal Article] Girdin is an intrinsic regulator of neuroblast chain migration in the rostral migratory stream of the postnatal brain.2011
- Author(s)
  Wang Y, Kaneko N, Asai N, Enomoto A, Isotani-Sakakibara M, Kato T, Asai M, Murakumo Y, Ota H, Hikita T, Namba T, Kuroda K, Kaibuchi K, Ming GL, Song H, Sawamoto K, Takahashi M.
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 31 Pages: 8109-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701051
[Journal Article] Girdin is an intrinsic regulator of neuroblast chain migration in the rostral migratory stream of the postnatal brain2011
- Author(s)
  Wang Y, Kaneko N, Asai N, Enomoto A, Isotani-Sakakibara M, Kato T, Asai M, Murakumo Y, Ota H, Hikita T, Namba T, Kuroda K, Kaibuchi K, Ming GL, Song H, Sawamoto K, Takahashi M
- Journal Title
  
  J Neurosci
  
  Volume: 31(22) Pages: 8109-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701051
[Journal Article] Analysis of glial cell line-derived neurotrophic factor-inducible zinc finger protein 1 expression in human diseased kidney.2011
- Author(s)
  Saito S, Murakumo Y, Tsuzuki T, Dambara A, Kato T, et al.
- Journal Title
  
  Hum Pathol. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890097
[Journal Article] An effective gene-knockdown using multiple shRNA-expressing adenovirus vectors2011
- Author(s)
  Motegi Y, Katayama K, Sakurai F, Kato T, Yamaguchi T, Matsui H, Takahashi M, Kawabata K, Mizuguchi H
- Journal Title
  
  J Control Release
  
  Volume: 153(2) Pages: 149-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701051
[Journal Article] Protective Role of Gipie, a Girdin Family Protein, in Endoplasmic Reticulum Stress Responses in Endothelial Cells.2011
- Author(s)
  Matsushita E, Asai N, Enomoto A, Kawamoto Y, Kato T, et al.
- Journal Title
  
  Mol Biol Cell. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890097
[Journal Article] Analysis of glial cell line-derived neurotrophic factor-inducible zinc finger protein 1 expression in human diseased kidney2011
- Author(s)
  Saito S, Murakumo Y, Tsuzuki T, Dambara A, Kato T, Enomoto A, Asai N, Maruyama S, Matsuo S, Takahashi M
- Journal Title
  
  Hum Pathol
  
  Volume: 42(6) Pages: 848-58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701051
[Journal Article] An effective gene-knockdown using multiple shRNA-expressing adenovirus vectors.2011
- Author(s)
  Motegi Y, Katayama K, Sakurai F, Kato T, Yamaguchi T, Matsui H, Takahashi M, Kawabata K, Mizuguchi H.
- Journal Title
  
  Journal of Control Release
  
  Volume: 153 Pages: 149-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701051
[Journal Article] Analysis of glial cell line-derived neurotrophic factor-inducible zinc finger protein 1 expression in human diseased kidney.2011
- Author(s)
  Saito S, Murakumo Y, Tsuzuki T, Dambara A, Kato T, Enomoto A, Asai N, Maruyama S, Matsuo S, Takahashi M.
- Journal Title
  
  Human pathology
  
  Volume: 42 Pages: 848-58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701051
[Journal Article] Roles of disrupted-in -schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus.2009
- Author(s)
  Enomoto A, Asai N, Namba T, Wang Y, Kato T, et al.
- Journal Title
  
  Neuron. 63
  
  Pages: 774-787
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890097
[Journal Article] Expression of Ret finger protein correlates with outcomes in endometrial cancer.2009
- Author(s)
  Tsukamoto H, Kato T, Enomoto A, Nakamura N, Shimono Y, et al.
- Journal Title
  
  Cancer Sci. 100
  
  Pages: 1895-1901
- NAID
  10027195768
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890097
[Journal Article] Characterization of the HDAC1 complex that regulates the sensitivity of cancer cells to oxidative stress.2009
- Author(s)
  Kato T, Shimono Y, Hasegawa M, Jijiwa M, Enomoto A, et al.
- Journal Title
  
  Cancer Res. 69
  
  Pages: 3597-3604
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890097
[Journal Article] Characterization of the HDAC1 complex that regulates the sensitivity of cancer cells to oxidative stress2009
- Author(s)
  Kato Takuya
- Journal Title
  
  Cancer Research 69
  
  Pages: 3597-3604
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890097
[Presentation] 肺扁平上皮癌におけるCD109の機能解析2019
- Author(s)
  加藤　琢哉、七浦　奈都実、宮下　結羽、櫻井　靖高、村雲　芳樹
- Organizer
  日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19K21262
[Presentation] Mechanism of pattern formation of cancer cell invasion2018
- Author(s)
  加藤　琢哉, Robert Jenkins, 村雲　芳樹, Erik Sahai
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-19K21262
[Presentation] 細胞接着因子の空間的ダイナミクスが関わるがん細胞の集団的移動のメカニズム2015
- Author(s)
  榎本篤、加藤琢哉、高橋雅英
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（名古屋市）
- Year and Date
  2015-10-08
- Invited
- Data Source
  KAKENHI-PROJECT-26640074
[Presentation] がん細胞の不均一性形成における間質の重要性2015
- Author(s)
  榎本篤、加藤琢哉、高橋雅英
- Organizer
  第104回日本病理学会総会
- Place of Presentation
  名古屋国際会議場（名古屋市）
- Year and Date
  2015-04-30
- Invited
- Data Source
  KAKENHI-PROJECT-26640074
[Presentation] TRIM27 - USP7 による p53 制御機構の解明2014
- Author(s)
  加藤　琢哉、榎本　篤、浅井　真人、浅井　直也、高橋　雅英
- Organizer
  第103回日本病理学会総会
- Place of Presentation
  広島国際会議場（広島県広島市）
- Year and Date
  2014-04-24
- Data Source
  KAKENHI-PROJECT-25830078
[Presentation] Regulatory mechanism of integrin beta1 expression in collectively migrating cancer cells2013
- Author(s)
  Kato, T., Enomoto, A., Asai, M., Asai, N., Takahashi, M
- Organizer
  9th AACR-JCA Joint Meeting
- Place of Presentation
  ハワイ、アメリカ合衆国
- Year and Date
  2013-02-23
- Data Source
  KAKENHI-PROJECT-23701051
[Presentation] Mechanisms underlying the integrin beta1 expression that define heterogeneity in migrating cancer cell collectives2013
- Author(s)
  Takuya Kato, Atsushi Enomoto, Masato Asai, Naoya Asai, Masahide Takahashi
- Organizer
  American Society for Cell Biology 2013 Annual Meeting
- Place of Presentation
  アメリカ合衆国、ニューオーリンズ
- Data Source
  KAKENHI-PROJECT-25830078
[Presentation] Regulatory mechanism of integrin beta1 expression in collectively migrating cancer cells2013
- Author(s)
  Takuya Kato
- Organizer
  Ninth AACR-Japanese Cancer Association Joint Conference
- Place of Presentation
  Maui, HI, USA
- Data Source
  KAKENHI-PROJECT-24650618
[Presentation] 移動するがん細胞集団内における多様性の確立機構2013
- Author(s)
  加藤　琢哉、榎本　篤、浅井　直也、村雲　芳樹、高橋　雅英
- Organizer
  日本病理学会総会
- Place of Presentation
  ロイトン札幌、札幌
- Data Source
  KAKENHI-PROJECT-25830078
[Presentation] がん細胞集団におけるLeadin Cellを規定する分子機構の解明2013
- Author(s)
  加藤　琢哉、榎本　篤、浅井　真人、浅井　直也、高橋　雅英
- Organizer
  日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜、横浜
- Data Source
  KAKENHI-PROJECT-25830078
[Presentation] RET finger protein related to early cancer recurrence and potential therapeutic target in ovarian cancer2012
- Author(s)
  Horio, M., Kato, T., Enomoto, A., Asai, N., Murakumo, Y., Shibata, K., Kikkawa, F. and Takahashi, M.
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌、札幌市
- Data Source
  KAKENHI-PROJECT-24650618
[Presentation] Regulatory mechanism of integrin beta1 expression in collectively migrating cancer cells2012
- Author(s)
  Kato, T., Enomoto, A., Haga, H., Ishida, S., Asai, M., Asai, N., Takahashi, M.
- Organizer
  The American Society of Cell Biology, 2012 Annual Meeting
- Place of Presentation
  サンフランシスコ、アメリカ合衆国
- Year and Date
  2012-12-18
- Data Source
  KAKENHI-PROJECT-23701051
[Presentation] Regulatory mechanism of integrin beta1 expression in collectively migrating cancer cells2012
- Author(s)
  加藤琢哉, 榎本篤, 浅井真人, 浅井直也, 村雲芳樹, 高橋雅英
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-23701051
[Presentation] 移動するがん細胞集団におけるintegrin beta1の発現制御機構2012
- Author(s)
  加藤琢哉
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌（札幌）
- Data Source
  KAKENHI-PROJECT-24650618
[Presentation] がん細胞の集団的浸潤の制御機構の解析2012
- Author(s)
  加藤琢哉, 榎本篤, 浅井直也, 村雲芳樹, 高橋雅英
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  東京
- Year and Date
  2012-04-28
- Data Source
  KAKENHI-PROJECT-23701051
[Presentation] Cell-cell contact dependent regulatory role of RFP in integrin beta1 expression2011
- Author(s)
  加藤琢哉, 榎本篤, 浅井直也, 村雲芳樹, 高橋雅英
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-23701051
[Presentation] Cell-cell contact dependent regulatory role of RFP in integrin beta1 expression.2011
- Author(s)
  加藤　琢哉
- Organizer
  日本癌学会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Data Source
  KAKENHI-PROJECT-23701051
[Presentation] Cell-cell contact dependent regulatory role of RFP in integrin beta1 expression.2011
- Author(s)
  Kato T, Enomoto A, Asai N, Murakumo Y, Takahashi M
- Organizer
  The American Society of Cell Biology, 2011 Annual Meeting
- Place of Presentation
  デンバー、アメリカ合衆国
- Year and Date
  2011-12-06
- Data Source
  KAKENHI-PROJECT-23701051
[Presentation] Cell-cell contact dependent regulatory role of RFP in integrin beta1 expression.2011
- Author(s)
  加藤　琢哉
- Organizer
  American Society For Cell Biology
- Place of Presentation
  Colorado Convention Center（コロラド州、アメリカ合衆国）
- Data Source
  KAKENHI-PROJECT-23701051
[Presentation] Role of RET finger protein in the integrin beta1 expression in cancer cells and its significance in cancer patients2011
- Author(s)
  加藤　琢哉
- Organizer
  American Association for Cancer Research
- Place of Presentation
  Orange County Convention Center（フロリダ州、アメリカ合衆国）
- Data Source
  KAKENHI-PROJECT-23701051
[Presentation] Regulation of cell motility by RFP and its significance in endometrial cancer2010
- Author(s)
  加藤琢哉
- Organizer
  8th AACR/JCA Joint Conference
- Place of Presentation
  ヒルトンワイコロアビレッジ(アメリカ)
- Year and Date
  2010-02-06
- Data Source
  KAKENHI-PROJECT-21890097
[Presentation] Regulation of the stability of integrin alpha2 by inteagrin betal2010
- Author(s)
  加藤琢哉
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21890097
[Presentation] Regulation of the stability of integrin alpha2 by inteagrin beta12010
- Author(s)
  加藤琢哉
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21890097
[Presentation] Regulation of cell motility by RFP and its significance in endometrial cancer2010
- Author(s)
  加藤琢哉
- Organizer
  8th AACR/JCA Joint Conference
- Place of Presentation
  ヒルトンワイコロアビレッジ(アメリカ合衆国)
- Year and Date
  2010-02-06
- Data Source
  KAKENHI-PROJECT-21890097
[Presentation] Regulation of cell motility by RFP and its significance in endometrial cancer2009
- Author(s)
  加藤琢哉
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-21890097
[Presentation] Regulation of cell motility by RFP and its significance in endometrial cancer2009
- Author(s)
  加藤琢哉
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-21890097
[Presentation] TRIM27-USP7によるp53制御機構の解明
- Author(s)
  加藤琢哉、榎本篤、三井伸二、浅井真人、浅井直也、高橋雅英
- Organizer
  第103回日本病理学会総会
- Place of Presentation
  広島国際会議場（広島県、広島市）
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-26640074
[Presentation] Regulatory mechanism of integrin beta1 expression in collectively migrating cancer cells.
- Author(s)
  加藤琢哉
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌（ロイトン札幌）
- Data Source
  KAKENHI-PROJECT-23701051
[Presentation] Regulatory mechanism of integrin beta1 expression in collectively migrating cancer cells.
- Author(s)
  Takuya Kato
- Organizer
  9th AACR-JCA Joint Meeting.
- Place of Presentation
  ハワイ（アメリカ）
- Data Source
  KAKENHI-PROJECT-23701051
[Presentation] Regulatory mechanism of integrin beta1 expression in collectively migrating cancer cells.
- Author(s)
  Takuya Kato
- Organizer
  The American Society of Cell Biology, 2012 Annual Meeting.
- Place of Presentation
  サンフランシスコ（アメリカ）
- Data Source
  KAKENHI-PROJECT-23701051
[Presentation] がん細胞の集団的浸潤の制御機構の解析
- Author(s)
  加藤琢哉
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  東京（京王プラザホテル）
- Data Source
  KAKENHI-PROJECT-23701051
[Presentation] A mechanism of integrin beta1 expression that difines leading cells in collective invasion of cancer
- Author(s)
  榎本篤、加藤琢哉、高橋雅英
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Invited
- Data Source
  KAKENHI-PROJECT-26640074
[]

1. TAKAHASHI Masahide (40183446)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
2. MURAKUMO Yoshiki (40324438)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
3. HIDESHI Ishii

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. ENOMOTO Atsushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. SHI Lei

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 黒田啓介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 櫻井靖高

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
8. 一戸昌明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 浅井直也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 吉川史隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 梶山広明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 眞山到

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kato Takuya 加藤 琢哉

KATO Takuya 加藤 琢哉

Research Projects

Research Products

Co-Researchers

Connexin 43 dependent mechanism for elimination of cancer cells from epithelial layerPrincipal Investigator

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Mechanism for pancreatic cancer cell survival against restraining CAFsPrincipal Investigator

Principal Investigator

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Review Section

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Mechanism of determining the invasive pattern of SCCPrincipal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Molecular Mechanisms of Collective Migration of Cancer Cells

Principal Investigator

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Research Institution

Regulatory mechanism of p53 deubiquitinating enzyme USP7Principal Investigator

Principal Investigator

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Research Institution

Mechanism of chemoresistance by HDAC1-associating protein and development of molecular targeted therapy

Principal Investigator

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Molecular mechanism for collective invasion of cancer cell groupsPrincipal Investigator

Principal Investigator

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Research Institution

Analysis of the regulatory mechanism of Lamin A degradation by RFP and its significance in malignant transformation.Principal Investigator

Principal Investigator

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Research Institution

[Journal Article] REV7 is involved in outcomes of platinum-based chemotherapy in pancreatic cancer via controlling the DNA damage response2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Interplay of adherens junctions and matrix proteolysis determines the invasive pattern and growth of squamous cell carcinoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] REV7 in Cancer Biology and Management2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinicopathological Significance of BRCAness in Resectable Pancreatic Ductal Adenocarcinoma and Its Association With Anticancer Drug Sensitivity in Pancreatic Cancer Cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Upregulation of REV7 correlates with progression of malignant melanoma2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Increased expression of REV7 in small cell lung carcinomas and its association with tumor cell survival and proliferation2020

Author(s)

Kato Takuya 加藤琢哉

KATO Takuya 加藤琢哉