Makino Akira 牧野顕

… Alternative Names

MAKINO Akira 牧野顕

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Researcher Number	00566226
Other IDs
Affiliation (Current)	2025: 福井大学, 高エネルギー医学研究センター, 准教授 2025: 京都大学, 薬学研究科, 研究員
Affiliation (based on the past Project Information) *help	2016 – 2024: 福井大学, 高エネルギー医学研究センター, 准教授 2016: 福井大学, 学内共同利用施設等, 准教授 2014 – 2015: 福井大学, 高エネルギー医学研究センター, 助教 2011: 京都大学, 大学院・薬学研究科, 特定助教 2011: 京都大学, 薬学研究科, 助教 2010: 株式会社島津製作所, 基盤技術研究所, 研究員
Review Section/Research Field	Principal Investigator Radiation science / Basic Section 52040:Radiological sciences-related Except Principal Investigator Basic Section 52040:Radiological sciences-related / Basic Section 57060:Surgical dentistry-related / Radiation science
Keywords	Principal Investigator 放射線 / PET / イメージングプローブ / 分子イメージング / 脳機能 / 自閉症スペクトラム障害 / 温度応答性 / 小線源療法 / 温度応答性高分子ミセル / 温度応答性ミセル … More / がん / 放射線内照射治療 / 併用療法 / 抗がん剤 / 体温応答性 / 高分子ミセル / 小線源治療 / 有機化学 / 酸化的 / 酵素触媒 / ハロゲン化 / 放射性ハロゲン / 酸化的ハロゲン化 / マンガンサレン錯体 / 酸化還元酵素 / ナノ材料 / 内照射治療 / 核医学イメージング / ナノ粒子 / アポフェリチン / CEST / 核磁気共鳴画像 … More Except Principal Investigator 分子イメージング / 酸化ストレス / PET/MRI / 認知症 / PET / マルチモダリティイメージング / 脳機能 / タウ / 分子病態 / アミロイド / タウPETイメージング / 糖鎖 / 歯性感染症 / 接触液胞二重膜法 / 細胞膜 / 核医学治療薬剤 / オキシトシン受容体 / ノルエピネフリン・トランスポータ / 発達障害 / 放射性薬剤 / 拡散テンソル / 拡散強調画像 / 機能的MRI / 変性タンパク / ナノ粒子 / インビボ / マウス / 体内動態 / セラノスティクス / 放射性標識合成 / 創薬 / SPECT / 放射性標識 / 腫瘍 Less

リン脂質組成に着目した膜標的型核医学治療薬剤精密設計のための開発基盤の構築
- Principal Investigator
  
  清野泰
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  University of Fukui
糖鎖・糖タンパク質を利用した歯性感染症の分子イメージング技術の開発
- Principal Investigator
  
  吉田寿人
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  University of Fukui
自閉症スペクトラム障害のメカニズム解明のための脳機能イメージングプローブの創製Principal Investigator
- Principal Investigator
  
  牧野顕
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  University of Fukui
Stratification and molecular pathogenesis of dementia based on tau pathology
- Principal Investigator
  
  岡沢秀彦
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  University of Fukui
Development of thermo-responsive micelle for combined region-specific chemo- and brachytherapiesPrincipal Investigator
- Principal Investigator
  
  Makino Akira
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  University of Fukui
Molecular imaging study investigating mechanism and pathophysiology of early stage dementia.
- Principal Investigator
  
  OKazawa Hidehiko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  University of Fukui
Development of PET molecular imaging probes for elucidation of pathophysiology and development of treatment for developmental disorders
- Principal Investigator
  
  Kiyono Yasushi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  University of Fukui
Development of rapid radioisotopes labeling method using oxidative halogenation reactionPrincipal Investigator
- Principal Investigator
  
  Makino Akira
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  University of Fukui
Development of radioiodine-labeled nanoparticle carrier with in vivo stability and tumor recognition ability for nuclear medicine
- Principal Investigator
  
  YAMAMOTO Fumihiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Tohoku Medical and Pharmaceutical University
Approaches to control in vivo dynamics of nanoparticle carriers for diagnosis and therapy in nuclear medicinal fieldsPrincipal Investigator
- Principal Investigator
  
  MAKINO Akira
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Radiation science
- Research Institution
  University of Fukui
Development of high sensitive MRI contrast agent encapsulating CEST agent into apoferritin cavityPrincipal Investigator
- Principal Investigator
  
  MAKINO Akira
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
  Shimadzu Corporation

All 2023 2022 2021 2020 2019 2017 2016 2015 2014 2011 Other

All Journal Article Presentation

[Journal Article] Cerebral Oxidative Stress in Early Alzheimer’s Disease Evaluated by 64Cu-ATSM PET/MRI: A Preliminary Study2022
- Author(s)
  Okazawa Hidehiko、Ikawa Masamichi、Tsujikawa Tetsuya、Mori Tetsuya、Makino Akira、Kiyono Yasushi、Nakamoto Yasunari、Kosaka Hirotaka、Yoneda Makoto
- Journal Title
  
  Antioxidants
  
  Volume: 11 Issue: 5 Pages: 1022-1022
- DOI
  10.3390/antiox11051022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19505, KAKENHI-PROJECT-20K07900, KAKENHI-PROJECT-23K24278
[Journal Article] Utilization of Antibody Allows Rapid Clearance of Nanoparticle Probes from Blood without the Need of Probe Modifications2021
- Author(s)
  Makino Akira、Okazawa Hidehiko、Kiyono Yasushi
- Journal Title
  
  ACS Omega
  
  Volume: 6 Issue: 32 Pages: 21153-21159
- DOI
  10.1021/acsomega.1c03076
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08094
[Journal Article] Noninvasive Measurement of [11C]PiB Distribution Volume Using Integrated PET/MRI2020
- Author(s)
  Okazawa Hidehiko、Ikawa Masamichi、Tsujikawa Tetsuya、Makino Akira、Mori Tetsuya、Kiyono Yasushi、Kosaka Hirotaka
- Journal Title
  
  Diagnostics
  
  Volume: 10 Issue: 12 Pages: 993-993
- DOI
  10.3390/diagnostics10120993
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07900, KAKENHI-PROJECT-18H02763
[Journal Article] Multimodal analysis using [11C]PiB-PET/MRI for functional evaluation of patients with Alzheimer’s disease.2020
- Author(s)
  Okazawa H, Ikawa M, Jung M, Maruyama R, Tsujikawa T, Mori T, Rahman MGM, Makino A, Kiyono Y, Kosaka H
- Journal Title
  
  Eur J Nucl Med Mol Img Res
  
  Volume: 10 Issue: 1 Pages: 30-30
- DOI
  10.1186/s13550-020-00619-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01846, KAKENHI-PROJECT-18H02763
[Journal Article] No significant difference found in PET/MRI CBF values reconstructed with CT-atlas-based and ZTE MR attenuation correction.2019
- Author(s)
  Okazawa H, Tsujikawa T, Higashino Y, Kikuta K, Mori T, Makino A, Kiyono Y
- Journal Title
  
  Eur J Nucl Med Mol Img Res
  
  Volume: 9 Issue: 1 Pages: 26-26
- DOI
  10.1186/s13550-019-0494-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H01846, KAKENHI-PROJECT-18H02763
[Journal Article] Inflammation-Induced Synergetic Enhancement of Nanoparticle Treatments with DOXIL® and ⁹⁰Y-Lactosome for Orthotopic Mammary Tumor2016
- Author(s)
  Shunsaku Kimura, Kensuke Kurihara, Motoki Ueda, Isao Hara, Eri Hara, Kohei Sano, Akira Makino, Eiichi Ozeki, Fumihiko Yamamoto, Hideo Saji, Kaori Togashi
- Journal Title
  
  J.Nanopart.Res.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09903
[Journal Article] Inflammation-induced synergetic enhancement of nanoparticle treatments with DOXIL and 90Y-Lactosome for orthotopic mammary tumor2016
- Author(s)
  Kensuke Kurihara, Motoki Ueda, Isao Hara, Eri Hara, Kohei Sano, Akira Makino, Eiichi Ozeki, Fumihiko Yamamoto, Hideo Saji, Kaori Togashi, Shunsaku Kimura
- Journal Title
  
  Journal of Nanoparticle Research
  
  Volume: 18 Issue: 5 Pages: 137-137
- DOI
  10.1007/s11051-016-3448-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26713040
[Journal Article] Inflammation-Induced Synergetic Enhancement of Nanoparticle Treatments with DOXI and 90Y-Lactosome for Orthotopic Mammary Tumor2016
- Author(s)
  Kensuke Kurihara, Motoki Ueda, Isao Hara, Eri Hara, Kohei Sano, Akira Makino, Eiichi Ozeki, Fumihiko Yamamoto, Hideo Saji, Kaori Togashi, Shunsaku Kimura
- Journal Title
  
  J.Nanopart.Res.
  
  Volume: 18 Pages: 137-137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09903
[Journal Article] Solid Tumor-Targeting Theranostic Polymer Nanoparticle in Nuclear Medicinal Fields2014
- Author(s)
  Akira Makino and Shunsaku Kimura
- Journal Title
  
  The Scientific World Journal
  
  Volume: 2014 Pages: 1-12
- DOI
  10.1155/2014/424513
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26713040
[Journal Article] Morphology control of molecular assemblies prepared from bio-based amphiphilic polymers with a helical hydrophobic unit and application as nanocarriers for contrast agents and/or drug delivery2014
- Author(s)
  Akira Makino
- Journal Title
  
  Polymer Journal
  
  Volume: 46 Issue: 11 Pages: 783-791
- DOI
  10.1038/pj.2014.73
- NAID
  40020248122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26713040
[Journal Article] Preparation of Peptide- and Protein-based Molecular Assemblies and Its Utilization as Nanocarriers for Tumor Imaging2011
- Author(s)
  牧野顕
- Journal Title
  
  Reactive and Functional Polymer
  
  Volume: 71 Pages: 271-279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791187
[Journal Article] Preparation of Peptide-and Protein-based Molecular Assemblies and Its Utilization as Nanocarriers for Tumor Imaging2011
- Author(s)
  Akira Makino, Shunsaku Kimura
- Journal Title
  
  React. Funct. Polym
  
  Volume: 71 Pages: 271-279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791187
[Journal Article] Effective encapsulation of a new cationic gadolinium chelate into apoferritin and its evaluation as an MRI contrast agent2011
- Author(s)
  Akira Makino, Hiroshi Harada, Tomohisa Okada, Hiroyuki Kimura, Hiroo Amano, Hideo Saji, Masahiro Hiraoka, Shunsaku Kimura
- Journal Title
  
  Nanomedicine, Nanotech. Biol. Med
  
  Volume: 7 Issue: 5 Pages: 638-646
- DOI
  10.1016/j.nano.2011.01.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791187
[Presentation] Increased oxidative stress in the brain of early Alzheimer’s disease.2023
- Author(s)
  Okazawa H, Ikawa M, Mori T, Makino A, Nogami M, Kiyono Y, Kosaka H.
- Organizer
  The 70th Annual Meeting of The Society of Nuclear Medicine and Molecular Imaging
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24278
[Presentation] Differences in cerebral oxidative stress between early Alzheimer’s disease and healthy controls analyzed using multimodality images from PET/MRI.2023
- Author(s)
  Okazawa H, Ikawa M, Mori T, Makino A, Nogami M, Kiyono Y, Kosaka H.
- Organizer
  Brain & Brain PET 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24278
[Presentation] Regional changes in cerebral oxidative stress in early Alzheimer’s disease.2022
- Author(s)
  Okazawa H, Ikawa M, Tsujikawa T, Mori T, Makino A, Kiyono Y, Kosaka H.
- Organizer
  Brain/Brain PET 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24278
[Presentation] Automated production of [18F]MK-6240 on AllinOne2022
- Author(s)
  Mori T, Makino A, Kiyono Y, Okazawa H
- Organizer
  WFNMB 2022 (世界核医学会)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24278
[Presentation] Comparison of oxidative stress in the brain of Alzheimer’s disease and healthy controls.2022
- Author(s)
  Okazawa H, Ikawa M, Tsujikawa T, Mori T, Makino A, Kiyono Y, Kosaka H.
- Organizer
  WFNMB 2022 (世界核医学会)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24278
[Presentation] Multimodal evaluation of brain functions in patients with Alzheimer’s disease using PiB-PET/MRI.2020
- Author(s)
  Okazawa H, Ikawa M, Jung M, Tsujikawa T, Mori T, Makino M, Kiyono Y, Kosaka H
- Organizer
  67th Annual Meeting of The Society of Nuclear Medicine and Molecular Imaging 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02763
[Presentation] 小線源療法のためのキャリアとしての生分解性温度応答性ミセルの評価2020
- Author(s)
  牧野顕、森哲也、岡沢秀彦、清野泰
- Organizer
  第60回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08094
[Presentation] Comparison of MR attenuation correction using CT-atlas based vs. zero-TE on quantitative 15O-water PET/MRI2019
- Author(s)
  Okazawa H, Tsujikawa T, Higashino Y, Mori T, Makino M, Kiyono Y.
- Organizer
  The 66th Annual Meeting of Society of Nuclear Medicine and Molecular Imaging
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02763
[Presentation] 組織内照射治療への応用が可能な温度応答性高分子ミセルの合成2019
- Author(s)
  牧野顕、森哲也、岡沢秀彦、清野泰
- Organizer
  第3回日本核医学会分科会放射性薬品科学研究会
- Data Source
  KAKENHI-PROJECT-19K08094
[Presentation] 福井から世界へ－分子イメージング最前線－2019
- Author(s)
  岡沢秀彦、辻川哲也、森哲也、牧野顕、清野泰
- Organizer
  第118回日本医学物理学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02763
[Presentation] 組織内照射と局所での化学療法とお併用を可能にするミセル製剤の開発2019
- Author(s)
  牧野顕、森哲也、岡沢秀彦、清野泰
- Organizer
  日本分子イメージング学会第14回総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K08094
[Presentation] Preparation and evaluation of biodegradable polymer micelle for brachytherapy2019
- Author(s)
  Akira Makino, Tetsuya Mori, Hidehiko Okazawa , Yasushi Kiyono
- Organizer
  European Association of Nuclear Medicine 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08094
[Presentation] 放射線内照射治療への応用を目指した温度応答性高分子ミセルの設計と合成2019
- Author(s)
  牧野顕、森哲也、岡沢秀彦、清野泰
- Organizer
  第68回高分子討論会
- Data Source
  KAKENHI-PROJECT-19K08094
[Presentation] Comparison of MR attenuation correction methods using CT-atlas vs. zero-TE on quantitative H215O-PET/MRI2019
- Author(s)
  Okazawa H, Tsujikawa T, Higashino Y, Mori T, Makino A, Kiyono Y.
- Organizer
  Brain PET 2019 (The 14th International Conference on Quantification of Brain Function with PET)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02763
[Presentation] Preparation and evaluation of biodegradable polymer micelle for brachytherapy.2019
- Author(s)
  Makino A, Mori T, Okazawa H, Kiyono Y
- Organizer
  32nd Annual Congress of the European Association of Nuclear Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02763
[Presentation] ナノ粒子をキャリアとしたイメージングプローブによる高コントラストイメージングのための基礎検討2017
- Author(s)
  牧野　顕、岡沢秀彦、清野　泰
- Organizer
  第12回日本分子イメージング学会学術集会
- Place of Presentation
  横浜港大さん橋ホール（神奈川県横浜市）
- Year and Date
  2017-05-25
- Data Source
  KAKENHI-PROJECT-26713040
[Presentation] 高分子ミセルプローブによる高コントラストイメージング法の開発2017
- Author(s)
  牧野　顕、岡沢秀彦、清野　泰
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-26713040
[Presentation] Evaluation of in vivo dynamics of the polymeric micelle by using two different radioisotope modification approaches2015
- Author(s)
  Akira Makino, Ayaka Tomoike, Masahiro Ono, Yasushi Kiyono, Hidehiko Okazawa, Hideo Saji
- Organizer
  Ninth Japan-China Joint Seminar on Radiopharmaceutical Chemistry (JCSRC2015)
- Place of Presentation
  千葉市
- Year and Date
  2015-11-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26713040
[Presentation] ナノ粒子の特性を活かした分子プローブの創製2014
- Author(s)
  牧野　顕, 清野　泰, 岡沢　秀彦
- Organizer
  第三回日本バイオマテリアル学会北陸若手研究発表会
- Place of Presentation
  福井県福井市・福井大学
- Year and Date
  2014-10-14
- Invited
- Data Source
  KAKENHI-PROJECT-26713040
[Presentation] ポジトロン断層撮影法（PET)のための18F標識分子プローブの開発について
- Author(s)
  牧野　顕
- Organizer
  平成26年度有機合成化学北陸セミナー
- Place of Presentation
  福井県坂井市・港のホテル
- Year and Date
  2014-10-03 – 2014-10-04
- Invited
- Data Source
  KAKENHI-PROJECT-26713040
[Presentation] オージェ電子を用いたナノ粒子型内照射治療薬剤に関する基礎検討
- Author(s)
  牧野　顕, 鹿沼俊樹, 坂下広幸, 浅井　竜哉, 岡沢　秀彦, 清野　泰
- Organizer
  第５４回日本核医学会学術総会
- Place of Presentation
  大阪市・大阪国際会議場
- Year and Date
  2014-11-06 – 2014-11-08
- Data Source
  KAKENHI-PROJECT-26713040

1. OKazawa Hidehiko (50360813)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
2. Kiyono Yasushi (50305603)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 辻川哲也 (30380033)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
4. 森哲也 (40397287)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
5. 井川正道 (60444212)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
6. 小坂浩隆 (70401966)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
7. YAMAMOTO Fumihiko (40253471)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. KIMURA Shunsaku (80150324)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 米田誠 (70270551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 小俣直人 (30334832)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 徳永雄次 (80250801)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 岩本真幸 (40452122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 吉田寿人 (40791794)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 松田慎平 (40632170)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 近藤堅司 (20933477)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 北章延 (50935145)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. OZEKI Ei-ichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
18. 平山暁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Makino Akira 牧野 顕

MAKINO Akira 牧野 顕

Research Projects

Research Products

Co-Researchers

リン脂質組成に着目した膜標的型核医学治療薬剤精密設計のための開発基盤の構築

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

糖鎖・糖タンパク質を利用した歯性感染症の分子イメージング技術の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

自閉症スペクトラム障害のメカニズム解明のための脳機能イメージングプローブの創製Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Stratification and molecular pathogenesis of dementia based on tau pathology

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of thermo-responsive micelle for combined region-specific chemo- and brachytherapiesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular imaging study investigating mechanism and pathophysiology of early stage dementia.

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Review Section

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Development of PET molecular imaging probes for elucidation of pathophysiology and development of treatment for developmental disorders

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Review Section

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Development of rapid radioisotopes labeling method using oxidative halogenation reactionPrincipal Investigator

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Development of radioiodine-labeled nanoparticle carrier with in vivo stability and tumor recognition ability for nuclear medicine

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Approaches to control in vivo dynamics of nanoparticle carriers for diagnosis and therapy in nuclear medicinal fieldsPrincipal Investigator

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Development of high sensitive MRI contrast agent encapsulating CEST agent into apoferritin cavityPrincipal Investigator

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[Journal Article] Cerebral Oxidative Stress in Early Alzheimer’s Disease Evaluated by 64Cu-ATSM PET/MRI: A Preliminary Study2022

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[Journal Article] Utilization of Antibody Allows Rapid Clearance of Nanoparticle Probes from Blood without the Need of Probe Modifications2021

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DOI

Makino Akira 牧野顕

MAKINO Akira 牧野顕

[Journal Article] Inflammation-Induced Synergetic Enhancement of Nanoparticle Treatments with DOXIL® and ⁹⁰Y-Lactosome for Orthotopic Mammary Tumor2016