Ohara Shinichiro 大原信一郎

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OHARA Shinichiro 大原信一郎

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Researcher Number	00566846
Affiliation (Current)	2025: 福島県立医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2014 – 2017: 福島県立医科大学, 医学部, 助教 2012: 福島県立医科大学, 医学部, 助手 2012: 福島県立医科大学, 医学部, 助教 2010 – 2011: 福島県立医科大学, 医学部, 病院助手
Review Section/Research Field	Principal Investigator Pediatrics Except Principal Investigator Pediatrics
Keywords	Principal Investigator 慢性腎障害 / 溶血性尿毒症症候群 / 小児 / 紫斑病性腎炎 Except Principal Investigator S100A9 / S100A8 / 内皮細胞障害 / アンギオポエチン1 / VEGF / HMGB1 … More / HUSモデル / rhTM / HUS / DAMPs / Acute renal injury / セリンプロテアーゼ / プロテアーゼ / アポトーシス / インフルエンザ Less

典型的溶血性尿毒症症候群における慢性腎障害の進展増悪因子の解明と新規治療法の開発Principal Investigator
- Principal Investigator
  
  大原信一郎
- Project Period (FY)
  2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Fukushima Medical University
The pathogenesisiof Henoch-schoenlein purpura nephritis: Role of circulation of defective forms of IgA1.Principal Investigator
- Principal Investigator
  
  Ohara Shinichiro
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Fukushima Medical University
The control and the role of DAMPs in acute and chronic renal injury
- Principal Investigator
  
  KAWASAKI Yukihiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Fukushima Medical University
An investigation and its control of the novel influenza virus replication mechanism using human upper respiratory airway model
- Principal Investigator
  
  SATO Masatoki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Fukushima Medical University

All 2018 2017 2016 2015 2013 2012 2011

All Journal Article Presentation

[Journal Article] 小児期発症常染色体優性多発性嚢胞腎における早期診断と腎容積測定の臨床的意義2018
- Author(s)
  大原信一郎, 他
- Journal Title
  
  日本小児科学会雑紙
  
  Volume: 122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16273
[Journal Article] Long-term follow up of pediatric immunoglobulin A nephropathy treated with tonsillectomy plus methylprednisolone pulse therapy2017
- Author(s)
  Kawasaki Y, Maeda R, Kanno S, Suzuki Y, Ohara S, Suyama K, Hosoya M
- Journal Title
  
  Pediatr Int
  
  Volume: 59 Issue: 1 Pages: 41-47
- DOI
  10.1111/ped.13074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461615
[Journal Article] ミゾリビン・タクロリムス併用療法が有効であったネフローゼ症候群合併重症ループス腎炎Ⅳ型の1例2017
- Author(s)
  大原信一郎, 他
- Journal Title
  
  日本小児腎不全学会雑誌
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19624
[Journal Article] ミゾリビン・タクロリムス併用療法が有効であったネフローゼ症候群合併重症ループス腎炎Ⅳ型の1例2017
- Author(s)
  大原信一郎, 他
- Journal Title
  
  日本小児腎不全学会雑誌
  
  Volume: 37 Pages: 170-173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16273
[Journal Article] Serum myeloid-related protein 8/14 level in minimal change- and glomerulonephritis-related nephrotic syndrome.2016
- Author(s)
  Ohara S, Kawasaki Y, et al.
- Journal Title
  
  Pediatric International
  
  Volume: 0 Issue: 10 Pages: 0-0
- DOI
  10.1111/ped.12947
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19624, KAKENHI-PROJECT-26461615
[Journal Article] Rituximab and low-dose cyclosporine combination therapy for steroid-resistant focal segmental glomerulosclerosis2016
- Author(s)
  陶山和秀，川崎幸彦，宮崎恭平，菅野修人，小野敦史，鈴木雄一，大原信一郎，細矢光亮
- Journal Title
  
  Pediatr Int
  
  Volume: 58 Issue: 3 Pages: 219-223
- DOI
  10.1111/ped.12804
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461615
[Journal Article] The efficacy of recombinant human soluble thrombomodulin for the treatment of shiga toxin-associated hemolytic uremic syndrome model mice.2016
- Author(s)
  陶山　和秀
- Journal Title
  
  nephrol Dial Transplant
  
  Volume: 6 Issue: 6 Pages: 969-977
- DOI
  10.1093/ndt/gfv004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461590, KAKENHI-PROJECT-26461615
[Journal Article] Differences in clinical findings, pathology, and outcomes between C3 glomerulonephritis and membranoproliferazive glomerulonephritis2016
- Author(s)
  Kawasaki Y, Ohara S, Suyama K, et al.
- Journal Title
  
  Pediatric Nephrology
  
  Volume: 31 Pages: 1091-1099
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19624
[Journal Article] Differences in clinical findings, pathology, and outcomes between C3 glomerulonephritis and membranoproliferative glomerulonephritis2016
- Author(s)
  Kawasaki Y, Kanno S, Ono A, Suzuki Y, Ohara S, Sato M, Suyama K, Hashimoto K, Hosoya M
- Journal Title
  
  Pediatr Nephrol
  
  Volume: 31 Issue: 7 Pages: 1091-1099
- DOI
  10.1007/s00467-015-3307-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461615
[Journal Article] 急性腎障害を契機に診断された後部尿道弁の4歳男児例2016
- Author(s)
  大原信一郎, 他
- Journal Title
  
  日本小児腎不全学会雑誌
  
  Volume: 36 Pages: 264-267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19624
[Journal Article] Serum myeloid-related protein 8/14 level in minimal change- and glomerulonephritis-related nephrotic syndrome2016
- Author(s)
  Ohara S, Kawasaki Y, Suyama K, et al.
- Journal Title
  
  Pediatric International
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19624
[Journal Article] Differnces in clinical findings, pathology, and outcomes between C3 glomerulonephritis and membranoproliferative glomerulonephritis.2016
- Author(s)
  Kawasaki Y, Ohara S, Suyama K, et al.
- Journal Title
  
  Pediatric Nephrology
  
  Volume: 0 Pages: 0-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19624
[Journal Article] Rituximab and low-dose cyclosporine combination therapy for steroid-resistant focal segmental glomerulosclerosis2016
- Author(s)
  Suyama K, Kawasaki Y, Ohara S, et al.
- Journal Title
  
  Pediatric International
  
  Volume: 58 Pages: 219-223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19624
[Journal Article] MRI画像により早期診断が可能であったWunderlich症候群の1女児例2015
- Author(s)
  大原信一郎、川崎幸彦、陶山和秀、他
- Journal Title
  
  日本小児腎臓病学会雑誌
  
  Volume: 28 Pages: 55-59
- NAID
  130005102920
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K19624
[Journal Article] 濃厚な家族歴と双角子宮を契機にWT1変異による遺伝性巣状分節性糸球体硬化症と診断した1症例2015
- Author(s)
  大原信一郎、他
- Journal Title
  
  日本小児腎不全学会雑誌
  
  Volume: 35 Pages: 135-138
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K19624
[Journal Article] Characteristics of viruses derived from nude mice with persistent measles virus infection.2013
- Author(s)
  Abe Y, Hashimoto K, Watanabe M, Ohara S, Sato M, Kawasaki Y, Hashimoto Y, Hosoya M.
- Journal Title
  
  J Virol.
  
  Volume: 87 Issue: 8 Pages: 4170-4175
- DOI
  10.1128/jvi.03117-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591187, KAKENHI-PROJECT-24591581
[Journal Article] Mumps Virus-Associated Acute Encephalopathy: Case Report and Review of the Literature2012
- Author(s)
  Watanabe M, Suyama K, Hashimoto K, Sato M, Ohara S, Abe Y, Kawasaki Y, Yamaguchi S, Saijo M, Hosoya M.
- Journal Title
  
  J Child Neurol.
  
  Volume: 28 Issue: 2 Pages: 243-245
- DOI
  10.1177/0883073812441060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591187, KAKENHI-PROJECT-24591581
[Journal Article] Uteroglobulin-related protein 1 and severity of respiratory syncytial virus infection in children admitted to hospital2011
- Author(s)
  Hashimoto K, et al
- Journal Title
  
  J Med Virol
  
  Volume: 83 Issue: 6 Pages: 1086-92
- DOI
  10.1002/jmv.22073
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591330, KAKENHI-PROJECT-21591394, KAKENHI-PROJECT-22591187
[Presentation] 当科で経験した先天性片側無機能腎25症例の腎予後と合併症の検討2017
- Author(s)
  大原信一郎, 他
- Organizer
  日本小児腎臓病学会
- Place of Presentation
  東京都
- Year and Date
  2017-06-01
- Data Source
  KAKENHI-PROJECT-17K16273
[Presentation] 先天性単腎症の早期診断と代償性腎肥大評価の臨床的意義2017
- Author(s)
  大原信一郎, 他
- Organizer
  日本腎臓学会東部学術大会
- Place of Presentation
  神奈川県
- Year and Date
  2017-10-28
- Data Source
  KAKENHI-PROJECT-17K16273
[Presentation] 腎後性急性腎不全を繰り返した多嚢胞性異形成腎の女児例2017
- Author(s)
  大原信一郎, 他
- Organizer
  日本小児腎不全学会
- Place of Presentation
  兵庫県
- Year and Date
  2017-09-21
- Data Source
  KAKENHI-PROJECT-17K16273
[Presentation] 小児期発症C3腎における予後推測因子の解析2016
- Author(s)
  川崎幸彦，前田亮，菅野修人，大原信一郎，陶山和秀
- Organizer
  第46回日本腎臓病学会東部学術大会
- Place of Presentation
  東京
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-26461615
[Presentation] 低補体血症を伴わない膜性増殖性糸球体腎炎Ⅲ型の女児例2016
- Author(s)
  大原信一郎
- Organizer
  日本腎臓学会東部学術大会
- Place of Presentation
  東京都
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-15K19624
[Presentation] ミゾリビン・タクロリムス併用療法が有効であったネフローゼ症候群合併重症ループス腎炎Ⅳ型の1例2016
- Author(s)
  大原信一郎
- Organizer
  日本小児腎不全学会
- Place of Presentation
  岐阜県岐阜市
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PROJECT-15K19624
[Presentation] 難治性ネフローゼ症候群の寛解導入における血漿交換とステロイドパルス療法併用の効果2016
- Author(s)
  大原信一郎
- Organizer
  日本小児科学会
- Place of Presentation
  北海道札幌市
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-15K19624
[Presentation] ミゾリビン・タクロリムス併用療法が有効であったネフローゼ症候群合併重症ループス腎炎Ⅳ型の1例2016
- Author(s)
  大原信一郎
- Organizer
  日本小児リウマチ学会
- Place of Presentation
  千葉県千葉市
- Year and Date
  2016-10-21
- Data Source
  KAKENHI-PROJECT-15K19624
[Presentation] 小児期に診断された常染色体優性多発性嚢胞腎（ADPKD）の臨床像2015
- Author(s)
  大原信一郎
- Organizer
  日本小児腎臓病学会
- Place of Presentation
  兵庫県
- Year and Date
  2015-06-18
- Data Source
  KAKENHI-PROJECT-15K19624
[Presentation] 小児期ADPKDの臨床像および腎容積と腎機能の関係2015
- Author(s)
  大原信一郎
- Organizer
  日本小児科学会
- Place of Presentation
  大阪府
- Year and Date
  2015-04-17
- Data Source
  KAKENHI-PROJECT-15K19624
[Presentation] 尿路感染に伴う急性腎障害を契機に診断した後部尿道弁の4歳男児例2015
- Author(s)
  大原信一郎
- Organizer
  日本小児腎不全学会
- Place of Presentation
  石川県
- Year and Date
  2015-11-26
- Data Source
  KAKENHI-PROJECT-15K19624
[Presentation] 過去8年間に福島県で発症した小児紫斑病性腎炎の検討2015
- Author(s)
  大原信一郎
- Organizer
  日本小児腎臓病学会
- Place of Presentation
  兵庫県
- Year and Date
  2015-06-18
- Data Source
  KAKENHI-PROJECT-15K19624
[Presentation] 小児難治性ネフローゼ症候群の寛解導入における血漿交換とステロイドパルス療法併用の効果2015
- Author(s)
  大原信一郎
- Organizer
  日本腎臓学会　東部学術集会
- Place of Presentation
  東京都
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-15K19624
[Presentation] インフルエンザウイルス感染細胞のアポトーシスとウイルス複製2011
- Author(s)
  佐藤晶論、Peter F Wright、渡部真裕、阿部優作、大原信一郎、橋本浩一、川崎幸彦、細矢光亮
- Organizer
  第43回日本小児感染症学会
- Place of Presentation
  岡山県岡山市
- Year and Date
  2011-10-30
- Data Source
  KAKENHI-PROJECT-22591187

1. 光亮 Mitsuaki (80192318)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
2. HASHIMOTO Kouichi (50322342)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. SATO Masatoki (60423795)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. KAWASAKI Yukihiko (00305369)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. 陶山和秀 (90423798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
6. 鈴木順造 (20171217)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

Ohara Shinichiro 大原 信一郎

OHARA Shinichiro 大原 信一郎

Research Projects

Research Products

Co-Researchers

典型的溶血性尿毒症症候群における慢性腎障害の進展増悪因子の解明と新規治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The pathogenesisiof Henoch-schoenlein purpura nephritis: Role of circulation of defective forms of IgA1.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The control and the role of DAMPs in acute and chronic renal injury

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

An investigation and its control of the novel influenza virus replication mechanism using human upper respiratory airway model

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 小児期発症常染色体優性多発性嚢胞腎における早期診断と腎容積測定の臨床的意義2018

Author(s)

Journal Title

Data Source

[Journal Article] Long-term follow up of pediatric immunoglobulin A nephropathy treated with tonsillectomy plus methylprednisolone pulse therapy2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ミゾリビン・タクロリムス併用療法が有効であったネフローゼ症候群合併重症ループス腎炎Ⅳ型の1例2017

Author(s)

Journal Title

Data Source

[Journal Article] ミゾリビン・タクロリムス併用療法が有効であったネフローゼ症候群合併重症ループス腎炎Ⅳ型の1例2017

Author(s)

Journal Title

Data Source

[Journal Article] Serum myeloid-related protein 8/14 level in minimal change- and glomerulonephritis-related nephrotic syndrome.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Rituximab and low-dose cyclosporine combination therapy for steroid-resistant focal segmental glomerulosclerosis2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The efficacy of recombinant human soluble thrombomodulin for the treatment of shiga toxin-associated hemolytic uremic syndrome model mice.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Differences in clinical findings, pathology, and outcomes between C3 glomerulonephritis and membranoproliferazive glomerulonephritis2016

Author(s)

Journal Title

Data Source

[Journal Article] Differences in clinical findings, pathology, and outcomes between C3 glomerulonephritis and membranoproliferative glomerulonephritis2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 急性腎障害を契機に診断された後部尿道弁の4歳男児例2016

Author(s)

Journal Title

Data Source

[Journal Article] Serum myeloid-related protein 8/14 level in minimal change- and glomerulonephritis-related nephrotic syndrome2016

Author(s)

Journal Title

Data Source

[Journal Article] Differnces in clinical findings, pathology, and outcomes between C3 glomerulonephritis and membranoproliferative glomerulonephritis.2016

Author(s)

Ohara Shinichiro 大原信一郎

OHARA Shinichiro 大原信一郎