OKOCHI Naoko 大河内直子

Researcher Number	00568412
Other IDs	https://orcid.org/0000-0002-2362-257X
Affiliation (based on the past Project Information) *help	2010 – 2013: 東京大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Hematology
Keywords	Principal Investigator model mouse / leukemia / Evi1 / TPO / cMpl / CD41 / C/EBPbeta / LIP / C/EBPβ / 血液腫瘍学

The role of megakaryocytic signals in Evi1 leukemiaPrincipal Investigator
- Principal Investigator
  
  OKOCHI Naoko
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
Establishment of murine model of Evi1-related leukemia and development of radical cure.Principal Investigator
- Principal Investigator
  
  OKOCHI Naoko
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo

All 2014 2013 2012 2011 2010

All Journal Article Presentation Book

[Book] 輸血合併症 : 今日の治療と看護改訂第3版2013
- Author(s)
  大河内直子, 高橋孝喜
- Data Source
  KAKENHI-PROJECT-24790961
[Book] アフェレシス療法ポケットマニュアル2010
- Author(s)
  大河内直子
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-22790899
[Journal Article] Single-cell gene expression analysis reveals clonal architecture of blast-phase chronic myeloid leukaemia2014
- Author(s)
  Nukina A, Kagoya Y, Watanabe-Okochi N, Arai S, Ueda K, Yoshimi A, Nannya Y, Kurokawa M
- Journal Title
  
  Br J Haematol
  
  Volume: (Epub ahead of print)
- Data Source
  KAKENHI-PROJECT-24790961
[Journal Article] Safety and efficacy of preoperative autologous blood donation for high-risk pregnant women : experience of a large university hospital in Japan2014
- Author(s)
  Yamamoto Y, Yamashita T, Tsuno NH, Nagamatsu T, Okochi N, Hyodo H, Ikeda T, Kawabata M, Kamei Y, Nagura Y, Sone S, Fujii T, Takahashi K, Kozuma S
- Journal Title
  
  J Obstet Gynaecol Res
  
  Volume: 40 Pages: 1308-16
- Data Source
  KAKENHI-PROJECT-24790961
[Journal Article] The role of alloantibodies against human platelet antigen-15 in multiply platelet transfused patients2014
- Author(s)
  Matsuhashi M, Tsuno NH, Sone S, Mishima Y, Nagura Y, Watanabe-Okochi N, Ikeda T, Kashiwase K, Fukuda S, Iriyama T, Hyodo H, Yamashita T, Kamei Y, Arai S, Minami M, Fujii T, Kurokawa M, Tozuka M, Takahashi K, Santoso S
- Journal Title
  
  Transfusion
  
  Volume: 54(4) Pages: 1093-9
- Data Source
  KAKENHI-PROJECT-24790961
[Journal Article] Single-cell gene expression analysis reveals clonal architecture of blast-phase chronic myeloid leukaemia.2013
- Author(s)
  Nukina A, Kagoya Y, Watanabe-Okochi N, Arai S, Ueda K, Yoshimi A, Nannya Y, and Kurokawa M.
- Journal Title
  
  Br J Haematol
  
  Volume: In Press Issue: 3 Pages: 580-91
- DOI
  10.1111/bjh.12726
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249055, KAKENHI-PROJECT-24790961, KAKENHI-PROJECT-24790964, KAKENHI-PROJECT-25670445, KAKENHI-PROJECT-26860474
[Journal Article] The shortest isoform of C/EBPβ, Liver inhibitory protein (LIP) , collaborates with Evi1 to induce AML in a mouse BMT model2013
- Author(s)
  Okochi, N., Yoshimi, A., Sato, T., Ikeda, T., Kumano, K., Taoka, K., Sato, Y., Shinohara, A., Tsuruta, A., Masuda, A., Yokota, H., Yatomi, Y., Takahashi, K., Kitaura, J., Kitamura, T. and Kurokawa, M
- Journal Title
  
  Blood
  
  Volume: 121 Issue: 20 Pages: 4142-4155
- DOI
  10.1182/blood-2011-07-368654
- NAID
  10031196292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249051, KAKENHI-PROJECT-23591369, KAKENHI-PROJECT-24249055, KAKENHI-PROJECT-24659457, KAKENHI-PROJECT-24790961, KAKENHI-PROJECT-24790964, KAKENHI-PUBLICLY-23130503
[Journal Article] The shortest isoform of C/EBPβ, Liver inhibitory protein (LIP), collaborates with Evi1 to induce AML in a mouse BMT model2013
- Author(s)
  Watanabe-Okochi N, Yoshimi A, Sato T, Ikeda T, Kumano K, Taoka K, Satoh Y, Shinohara A, Tsuruta T, Masuda A, Yokota H, Yatomi Y, Takahashi K, Kitaura J, Kitamura T, Kurokawa M
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 54(8) Pages: 749-58
- NAID
  10031196292
- Data Source
  KAKENHI-PROJECT-24790961
[Journal Article] The shortest isoform of C/EBPβ, Liver inhibitory protein (LIP), collaborates with Evi1 to induce AML in a mouse BMT model2013
- Author(s)
  Watanabe-Okochi N, Yoshimi A, Sato T, Ikeda T, Kumano K, Taoka K, Satoh Y, Shinohara A, Tsuruta T, Masuda A, Yokota H, Yatomi Y, Takahashi K, Kitaura J, Kitamura T, Kurokawa M
- Journal Title
  
  Blood
  
  Volume: 121(20) Pages: 4142-55
- NAID
  10031196292
- Data Source
  KAKENHI-PROJECT-24790961
[Journal Article] 輸血検査2013
- Author(s)
  三島由布子、大河内直子
- Journal Title
  
  臨床検査
  
  Volume: 1 Pages: 34-40
- Data Source
  KAKENHI-PROJECT-24790961
[Journal Article] A role for RUNX1 in hematopoiesis and myeloid leukemia2013
- Author(s)
  Ichikawa M, Yoshimi A, Nakagawa M, Nishimoto N, Watanabe-Okochi N, Kurokawa M
- Journal Title
  
  Int J Hematol
  
  Volume: 97(Review) Pages: 726-34
- Data Source
  KAKENHI-PROJECT-24790961
[Journal Article] The current status of autologous blood transfusion in Japan - The importance of pre-deposit autologous blood donation program and the needs to achieve patient blood management2013
- Author(s)
  Tsuno NH, Nagura Y, Kawabata M, Matsuhashi M, Sone S, Ikeda T, Okochi N, Takahashi K
- Journal Title
  
  Transfus Apher Sci
  
  Volume: 49(3) Pages: 673-80
- Data Source
  KAKENHI-PROJECT-24790961
[Journal Article] The frequencies of SLC44A2 alleles among the Japanese population2013
- Author(s)
  Matsuhashi M, Tsuno NH, Ikeda T, Mishima Y, Watanabe-Okochi N, Santoso S, Tozuka M, Takahashi K
- Journal Title
  
  Tissue Antigens
  
  Volume: 81(4) Pages: 227-8
- Data Source
  KAKENHI-PROJECT-24790961
[Journal Article] Prediction model for CD34 positive cell yield in peripheral blood stem cell collection on the fourth day after G-CSF administration in healthy donors2013
- Author(s)
  Yoshizato T, Watanabe-Okochi N, Nannya Y, Ichikawa M, Takahashi T, Sato T, Masuda A, Yatomi Y, Tsuno NH, Kurokawa M, Takahashi K
- Journal Title
  
  Int J Hematol
  
  Volume: 98(1) Pages: 56-65
- Data Source
  KAKENHI-PROJECT-24790961
[Journal Article] Evi1の活性化と白血病-病態と予後に関する最近の知見2010
- Author(s)
  大河内直子
- Journal Title
  
  血液・腫瘍科
  
  Volume: 61 Pages: 746-746
- NAID
  40019063966
- Data Source
  KAKENHI-PROJECT-22790899
[Journal Article] Evi1の活性化と白血病-病態と予後に関する最近の知見2010
- Author(s)
  大河内直子, 他
- Journal Title
  
  血液・腫瘍科
  
  Pages: 746-746
- NAID
  40019063966
- Data Source
  KAKENHI-PROJECT-22790899
[Presentation] Evi1-induced leukemic cells express CD41 known as a megakaryocytic marker in a mouse BMT bone marrow transplantation model2012
- Author(s)
  大河内直子
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-14
- Data Source
  KAKENHI-PROJECT-24790961
[Presentation] Evi1-induced leukemic cells express CD41 known as a megakaryocytic marker in a mouse BMT model.2012
- Author(s)
  大河内直子
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24790961
[Presentation] Evi1-induced leukemic cells express CD41 known as a megakaryocytic marker in a mouse BMT bone marrow transplantation model.2012
- Author(s)
  大河内直子
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24790961
[Presentation] Evi1-induced leukemic cells express CD41 known as a megakaryocytic marker in a mouse BMT model2012
- Author(s)
  大河内直子
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都
- Year and Date
  2012-10-19
- Data Source
  KAKENHI-PROJECT-24790961
[Presentation] C/EBPbetaのアイソフォームであるLIPはEvilと協調作用して急性骨髄性白血病を誘発する2011
- Author(s)
  大河内直子
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-22790899
[Presentation] C/EBPbetaのアイソフォームであるLIPはEvi1と協調作用して急性骨髄性白血病を誘発する2011
- Author(s)
  大河内直子
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-22790899
[Presentation] Evi1関連白血病モデルマウスの作成と解析2010
- Author(s)
  大河内直子
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22790899
[Presentation] Evi1関連白血病モデルマウスの作成と解析2010
- Author(s)
  大河内直子
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-22790899

1. 黒川峰夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 北村俊雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 北浦次郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OKOCHI Naoko 大河内 直子

Research Projects

Research Products

Co-Researchers

The role of megakaryocytic signals in Evi1 leukemiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of murine model of Evi1-related leukemia and development of radical cure.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 輸血合併症 : 今日の治療と看護 改訂第3版2013

Author(s)

Data Source

[Book] アフェレシス療法ポケットマニュアル2010

Author(s)

Publisher

Data Source

[Journal Article] Single-cell gene expression analysis reveals clonal architecture of blast-phase chronic myeloid leukaemia2014

Author(s)

Journal Title

Data Source

[Journal Article] Safety and efficacy of preoperative autologous blood donation for high-risk pregnant women : experience of a large university hospital in Japan2014

Author(s)

Journal Title

Data Source

[Journal Article] The role of alloantibodies against human platelet antigen-15 in multiply platelet transfused patients2014

Author(s)

Journal Title

Data Source

[Journal Article] Single-cell gene expression analysis reveals clonal architecture of blast-phase chronic myeloid leukaemia.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The shortest isoform of C/EBPβ, Liver inhibitory protein (LIP) , collaborates with Evi1 to induce AML in a mouse BMT model2013

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] The shortest isoform of C/EBPβ, Liver inhibitory protein (LIP), collaborates with Evi1 to induce AML in a mouse BMT model2013

Author(s)

Journal Title

NAID

Data Source

[Journal Article] The shortest isoform of C/EBPβ, Liver inhibitory protein (LIP), collaborates with Evi1 to induce AML in a mouse BMT model2013

Author(s)

Journal Title

NAID

Data Source

[Journal Article] 輸血検査2013

Author(s)

Journal Title

Data Source

[Journal Article] A role for RUNX1 in hematopoiesis and myeloid leukemia2013

Author(s)

Journal Title

Data Source

[Journal Article] The current status of autologous blood transfusion in Japan - The importance of pre-deposit autologous blood donation program and the needs to achieve patient blood management2013

Author(s)

Journal Title

Data Source

[Journal Article] The frequencies of SLC44A2 alleles among the Japanese population2013

Author(s)

Journal Title

Data Source

[Journal Article] Prediction model for CD34 positive cell yield in peripheral blood stem cell collection on the fourth day after G-CSF administration in healthy donors2013

Author(s)

Journal Title

Data Source

[Journal Article] Evi1の活性化と白血病-病態と予後に関する最近の知見2010

Author(s)

Journal Title

NAID

OKOCHI Naoko 大河内直子

[Book] 輸血合併症 : 今日の治療と看護改訂第3版2013