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SERIZAWA MASAKUNI  芹澤 昌邦

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… Alternative Names

芹澤 昌邦  セリザワ マサクニ

Serizawa Masakuni  芹澤 昌邦

SERIZAWA Masakuni  芹澤 昌邦

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Researcher Number 00569915
Other IDs
Affiliation (Current) 2020: 静岡県立静岡がんセンター(研究所), その他部局等, 研究員
Affiliation (based on the past Project Information) *help 2019: 静岡県立静岡がんセンター(研究所), その他部局等, 研究員
2017: 静岡県立静岡がんセンター(研究所), その他部局等, 主任研究員
2014 – 2015: 静岡県立静岡がんセンター(研究所), その他部局等, 主任研究員
2014: 静岡県立静岡がんセンター研究所, 新規薬剤開発・評価研究部, 研究員
2013 – 2014: 静岡県立静岡がんセンター(研究所), その他部局等, その他 … More
2013: 静岡県立静岡がんセンター(研究所), その他部局等, 任期付研究員
2012: 静岡県立静岡がんセンター(研究所), 研究員
2011 – 2012: 静岡県立静岡がんセンター(研究所), その他部局等, 研究員 Less
Review Section/Research Field
Principal Investigator
Tumor therapeutics / Respiratory organ internal medicine / Tumor biology / Basic Section 50020:Tumor diagnostics and therapeutics-related
Except Principal Investigator
Respiratory organ internal medicine
Keywords
Principal Investigator
EGFR-TKI / GLUT1 / PET / 治療効果予測マーカー / 肺癌 / mTOR阻害剤 / FDG / mTOR / 肺がん / 個別化医療 … More / 分子標的型抗がん剤 / グルコース / 非小細胞肺癌 / EGFR-TKI耐性 / 転移 / 細胞遊走 / TGF-βシグナル / 細胞遊走能 / TGF-β / PPARγ / CRKL / がん代謝標的療法 / 肺腺癌 / 耐性 / オシメルチニブ / メタボローム解析 / がんゲノム医療 / 分子標的治療 / AI / VUS … More
Except Principal Investigator
遺伝子異常 / バイオバンク / 分子標的治療 / 遺伝子変異 / 肺癌 Less
  • Research Projects

    (5 results)
  • Research Products

    (25 results)
  • Co-Researchers

    (13 People)
  •  がんゲノム解析で蓄積する機能未知遺伝子変異の臨床活用にむけた変異機能推定法の構築Principal InvestigatorOngoing

    • Principal Investigator
      芹澤 昌邦
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Shizuoka Cancer Center Research Institute
  •  Development of metabolic-targeting therapy for overcoming resistance to EGFR-TKIs in non-small cell lung cancer cellsPrincipal Investigator

    • Principal Investigator
      Serizawa Masakuni
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor therapeutics
    • Research Institution
      Shizuoka Cancer Center Research Institute
  •  Investigation of novel molecular mechanisms associated with the metastasis of epidermal growth-factor receptor-tyrosine kinase inhibitor-resistant non-small cell lung cancerPrincipal Investigator

    • Principal Investigator
      SERIZAWA Masakuni
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Tumor therapeutics
      Tumor biology
    • Research Institution
      Shizuoka Cancer Center Research Institute
  •  Molecular profiling and biomarker study of thoracic malignancies

    • Principal Investigator
      YAMAMOTO Nobuyuki
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Wakayama Medical University
      Shizuoka Cancer Center Research Institute
  •  Investigation of the biological mechanism of GLUT1 to develop it as a novel therapeutic predictive biomarker for realization of the personalized lung cancer medicinePrincipal Investigator

    • Principal Investigator
      SERIZAWA Masakuni
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Shizuoka Cancer Center Research Institute

All 2020 2019 2016 2014 2013 2012 2011

All Journal Article Presentation

  • [Journal Article] Hypoxia Inducible Factor-1α Inhibition in Von Hippel Lindau-mutant Malignant Pleural Mesothelioma Cells.2020

    • Author(s)
      Shukuya T, Oyanagi J, Serizawa M, Watanabe M, Yamamoto N, Koh Y.
    • Journal Title

      Anticancer Res.

      Volume: 40 Pages: 1867-1874

    • DOI

      10.21873/anticanres.14140

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07792
  • [Journal Article] Assessment of associations between clinical and immune microenvironmental factors and tumor mutation burden in resected nonsmall cell lung cancer by applying machine learning to whole-slide images2020

    • Author(s)
      Ono A, Terada Y, Kawata T, Serizawa M, Isaka M, Kawabata T, Imai T, Mori K, Muramatsu K, Hayashi I, Kenmotsu H, Ohshima K, Urakami K, Nagashima T, Kusuhara M, Akiyama Y, Sugino T, Ohde Y, Yamaguchi K, Takahashi T.
    • Journal Title

      Cancer Med

      Volume: -

    • DOI

      10.1002/cam4.3107

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07792, KAKENHI-PROJECT-17K07209
  • [Journal Article] The Pathologic and Genetic Characteristics of the Intestinal Subtype of Intraductal Papillary Neoplasms of the Bile Duct.2019

    • Author(s)
      Nakanuma Y, Kakuda Y, Fukumura Y, Sugino T, Uesaka K, Serizawa M, Terada T, Ohnishi Y.
    • Journal Title

      Am J Surg Pathol.

      Volume: 43 Pages: 1212-1220

    • DOI

      10.1097/pas.0000000000001295

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07792
  • [Journal Article] Characterization of Tumour Mutation Burden in Patients With Non-Small Cell Lung Cancer and Interstitial Lung Disease2019

    • Author(s)
      Kobayashi H, Serizawa M, Naito T, Konno H, Kojima H, Mizuno T, Isaka M, Endo M, Nagashima T, Kusuhara M, Urakami K, Ohshima K, Yamaguchi K, Ohde Y, Takahashi T.
    • Journal Title

      Respirology

      Volume: -

    • DOI

      10.1111/resp.13726

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07792
  • [Journal Article] Novel tumor-specific mutations in receptor tyrosine kinase subdomain IX significantly reduce extracellular signal-regulated kinase activity2016

    • Author(s)
      Masakuni Serizawa, Masatoshi Kusuhara, Sumiko Ohnami, Takeshi Nagashima, Yuji Shimoda, Keiichi Ohshima, Tohru Mochizuki, Kenichi Urakami, Ken Yamaguchi
    • Journal Title

      Anticancer Research

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K06893
  • [Journal Article] Peroxisome proliferator-activated receptor γ agonist efatutazone impairs transforming growth factor β2-induced motility of epidermal growth factor receptor tyrosine kinase inhibitor-resistant lung cancer cells2014

    • Author(s)
      Sakai K
    • Journal Title

      Cancer Science

      Volume: 104 Pages: 1198-204

    • DOI

      10.1111/cas.12411

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590098, KAKENHI-PROJECT-24501363, KAKENHI-PROJECT-24591186, KAKENHI-PROJECT-25871225
  • [Journal Article] Identification of metabolic signatures associated with erlotinib resistance of non-small cell lung cancer cells2014

    • Author(s)
      Masakuni Serizawa, Masatoshi Kusuhara, Vincent Zangiacomi, Kenichi Urakami, Masaru Watanabe, Toshiaki Takahashi, Ken Yamaguchi, Nobuyuki Yamamoto, Yasuhiro Koh
    • Journal Title

      Anticancer Research

      Volume: 34(6) Pages: 2779-2788

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25871225
  • [Journal Article] Assessment of Mutational Profile of Japanese Lung Adenocarcinoma Patients by Multitarget Assays: A Prospective Single-institute Study2014

    • Author(s)
      Masakuni Serizawa
    • Journal Title

      Cancer

      Volume: 120 Pages: 1471-1481

    • DOI

      10.1002/cncr.28604

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24501363, KAKENHI-PROJECT-24591186
  • [Journal Article] Combined treatment with erlotinib and a transforming growth factor-β type I receptor inhibitor effectively suppresses the enhanced motility of erlotinib-resistant non-small cell lung cancer cells2013

    • Author(s)
      Masakuni Serizawa
    • Journal Title

      Journal of Thoracic Oncology

      Volume: 8 Pages: 259-69

    • DOI

      10.1097/jto.0b013e318279e942

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24501363, KAKENHI-PROJECT-24591186
  • [Journal Article] Genomic Aberrations Associated with Erlotinib-resistance in Non-small Cell Lung Cancer Cells2013

    • Author(s)
      Masakuni Serizawa, Toshiaki Takahashi, Nobuyuki Yamamoto and Yasuhiro Koh
    • Journal Title

      Anticancer Research

      Volume: 33(12) Pages: 5223-5233

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25871225
  • [Journal Article] Combined treatment with erlotinib and transforming growth factor-β type 1 receptor (TGF-βRI) inhibitor is effective to suppress the enhanced cell motility of erlotinib-resistant non-small cell lung cancer cells.2013

    • Author(s)
      Serizawa, M., Takahashi, T., Yamamoto, N., Koh, Y.
    • Journal Title

      J Thorac Oncol.

      Volume: 8 Pages: 259-269

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790928
  • [Journal Article] Genomic aberrations associated with erlotinib resistance in non-small cell lung cancer cells2013

    • Author(s)
      Masakuni Serizawa
    • Journal Title

      Anticancer Research

      Volume: 33 Pages: 5223-33

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591186
  • [Journal Article] The impact of clinical outcomes according to EGFR mutation status in patients with locally advanced lung adenocarcinoma who received concurrent chemoradiotherapy2012

    • Author(s)
      Akamatsu, H., Kaira, K., Murakami, H., Serizawa, M., Koh, Y., Ono, A., Shukuya, T., Tsuya, A., Nakamura, Y., Kenmotsu, H., Naito, T., Takahashi, T., Endo, M., Harada, H., Nakajima, T., Yamamoto, N.
    • Journal Title

      Am J Clin Oncol.

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790928
  • [Journal Article] Relationship between 18F-FDG uptake on positron emission tomography and molecular biology in malignant pleural mesothelioma.2012

    • Author(s)
      Kaira, K., Serizawa, M., Koh, Y., Takahashi, T., Hanaoka, H., Oriuchi, N., Endo, M., Kondo, H., Nakajima, T., Yamamoto, N.
    • Journal Title

      Eur J Cancer.

      Volume: 48 Pages: 1244-1254

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790928
  • [Journal Article] Relationship between (18)F-FDG uptake on positron emission tomography and molecular biology in malignant pleural mesothelioma2012

    • Author(s)
      Relationship between 18F-FDG uptake on positron emission tomography and molecular biology in malignant pleural mesothelioma.
    • Journal Title

      European Journal of Cancer

      Volume: 48 Pages: 1244-1254

    • DOI

      10.1016/j.ejca.2012.01.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591750, KAKENHI-PROJECT-23790928
  • [Journal Article] バイオバンクと個別化医療2011

    • Author(s)
      芹澤昌邦、洪 泰浩
    • Journal Title

      Progress in Medicine 基礎・治療

      Volume: 31 Pages: 2575-2580

    • Data Source
      KAKENHI-PROJECT-23790928
  • [Journal Article] Expression of excision repair cross-complementation group 1, breast cancer susceptibility 1, and β III-tubulin in thymic epithelial tumors.2011

    • Author(s)
      Kaira, K., Serizawa M., Koh, Y., Miura, S., Kaira, R., Abe, M., Nakagawa, K., Ohde, Y., Okumura, T., Naito, T., Murakami, H., Takahashi, T., Kondo, H., Nakajima, T., Endo, M., Yamamoto, N.
    • Journal Title

      J Thorac Oncol.

      Volume: 6 Pages: 606-613

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790928
  • [Journal Article] MUC1 expression in thymic epithelial tumors: MUC1 may be useful marker as differential diagnosis between type B3 thymoma and thymic carcinoma.2011

    • Author(s)
      Kaira, K., Murakam,I H., Serizawa, M., Koh, Y., Abe, M., Ohde, Y., Takahashi, T., Kondo, H., Nakajima, T., Yamamoto, N.
    • Journal Title

      Virchows Arch.

      Volume: 458 Pages: 615-620

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790928
  • [Journal Article] Expression of thymidylate synthase, orotate phosphoribosyltransferase and dihydropyrimidine dehydrogenase in thymic epithelial tumors.2011

    • Author(s)
      Kaira, K, Serizawa, M., Koh, Y., Miura, S., Kaira, R., Abe, M., Nakagawa, K., Ohde, Y., Okumura, T., Murakami, H., Tsuya, A., Nakamura, Y., Naito, T., Takahashi, T., Kondo, H., Nakajima, T., Endo, M., Yamamoto, N.
    • Journal Title

      Lung Cancer.

      Volume: 74 Pages: 419-425

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790928
  • [Presentation] オシメルチニブ耐性非小細胞肺癌細胞において活性の変化を示す代謝経路の同定2019

    • Author(s)
      梅原里奈、宮脇英里子、釼持広知、大島啓一、浦上研一、解良恭一, 高橋利明、山口 建 、芹澤昌邦
    • Organizer
      第78回 日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K07792
  • [Presentation] 主要8がん種における日本人と白人のがんゲノム比較解析2019

    • Author(s)
      芹澤昌邦、長嶋剛史、川端孝典、盛 啓太、釼持広知、杉野 隆、丸山宏二、大島啓一、浦上研一、秋山靖人、山口 建
    • Organizer
      第78回 日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K07792
  • [Presentation] 遺伝子変異総量は非置換型肺腺癌における独立した予後規定因子である2019

    • Author(s)
      井坂光宏、芹澤昌邦、長嶋剛史、児嶋秀晃、今野隼人、水野鉄也、小野 哲、大島啓一、秋山靖人、浦上研一、遠藤正浩、杉野 隆、山口 建、高橋利明、大出泰久
    • Organizer
      第78回 日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K07792
  • [Presentation] 肺腺癌における個別化医療の推進を目的とした体細胞変異プロファイリング2013

    • Author(s)
      芹澤昌邦
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜市
    • Invited
    • Data Source
      KAKENHI-PROJECT-24591186
  • [Presentation] Implementation of multiplexed mutational profiling into the lung cancer clinic at Shizuoka Cancer Center2012

    • Author(s)
      芹澤昌邦
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-24591186
  • [Presentation] Multiplexed mutational profiling in Japanese patients with thoracic malignancies for personalized cancer therapy2012

    • Author(s)
      Masakuni Serizawa
    • Organizer
      EORTC-NCI-AACR Symposium on 'Molecular Targets and Cancer Therapeutics'
    • Place of Presentation
      ダブリン(アイルランド)
    • Data Source
      KAKENHI-PROJECT-24591186
  • 1.  YAMAMOTO Nobuyuki (60298966)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  KOH Yasuhiro (80426519)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  KONDO Haruhiko (60399590)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  NAKAJIMA Takashi (20124422)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  楠原 正俊 (40169991)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  高橋 利明 (50507415)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  解良 恭一 (40400783)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  石川 吉伸 (00305004)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  大島 啓一 (10399587)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 10.  釼持 広知 (50602637)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 11.  盛 啓太 (50727534)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 12.  ENDO Masahiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  秋山 靖人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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