Sakai Kenji 坂井健二

Researcher Number	00572306
Other IDs
Affiliation (based on the past Project Information) *help	2020 – 2022: 金沢大学, 附属病院, 講師 2016 – 2019: 金沢大学, 附属病院, 助教 2014 – 2015: 金沢大学, 大学病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 52020:Neurology-related / Human pathology Except Principal Investigator Neurology / Medium-sized Section 52:General internal medicine and related fields
Keywords	Principal Investigator 炎症 / アミロイドβ蛋白 / マウスモデル / 脳間質液 / 病理 / 脳脊髄液バイオマーカー / 動物モデル / 脳アミロイドアンギオパチー関連炎症 / アミロイド / 脳血管障害 … More / 神経病理 / 脳神経内科 / 遺伝子多型 / 脳アミロイドアンギオパチー … More Except Principal Investigator 伝播 / アミロイドβ蛋白 / アルツハイマー病 / アミロイドβタンパク質(Aβ) / 脳アミロイドアンギオパチー(CAA) / 全国調査 / Aβ排泄経路 / アミロイドβタンパク質（Aβ） / 脳神経外科手術 / 脳アミロイドアンギオパチー（CAA） / 剖検脳 / 脳アミロイドアンギオパチー / アミロイドβタンパク / γ線照射 / オートクレーブ処理 / 凝集 / 防御 Less

脳アミロイドアンギオパチー関連炎症における補体の検討と治療法開発Principal Investigator
- Principal Investigator
  
  坂井健二
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kanazawa University
Pathomechanistic analysis of animal model of cerebral amyloid angiopathy-related inflammationPrincipal Investigator
- Principal Investigator
  
  Sakai Kenji
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kanazawa University
Aquired cerebral amyloid angiopathy due to neurosurgery
- Principal Investigator
  
  Yamada Masahito
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Kanazawa University
Study on transmission of Abeta aggregates and its prevention
- Principal Investigator
  
  Yamada Masahito
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Kanazawa University
Study on transmission of sporadic cerebral amyloid angiopathy
- Principal Investigator
  
  YAMADA Masahito
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Kanazawa University
Pathomechanisms of cerebral amyloid angiopathy-related inflammationPrincipal Investigator
- Principal Investigator
  
  Sakai Kenji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Kanazawa University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation Book

[Book] 高血圧性以外の脳小血管病：脳アミロイドアンギオパチー、CADASIL、CARASIL、HDLS（認知症診療実践ハンドブック　改訂2版）2021
- Author(s)
  坂井健二（編著　山田正仁）
- Total Pages
  439
- Publisher
  中外医学社
- ISBN
  9784498228931
- Data Source
  KAKENHI-PROJECT-19K07958
[Book] Stroke Revisited: Pathophysiology of Stroke2020
- Author(s)
  Yamada M, Sakai K, Hamaguchi T, Noguchi-Shinohara M.
- Total Pages
  291
- Publisher
  Springer
- ISBN
  9789811014291
- Data Source
  KAKENHI-PROJECT-19K22593
[Book] Stroke Revised: Pathophysiology of Stroke2020
- Author(s)
  Yamada M, Sakai K, Hamaguchi T, Noguchi-Shinohara M
- Publisher
  Springer
- ISBN
  9789811014307
- Data Source
  KAKENHI-PROJECT-19K07958
[Book] Stroke Revisited: Pathophysiology of Stroke2020
- Author(s)
  Yamada M, Sakai K, Hamaguchi T, Noguchi-Shinohara M
- Total Pages
  291
- Publisher
  Springer
- ISBN
  9789811014291
- Data Source
  KAKENHI-PROJECT-17H04194
[Book] 最新アミロイドーシスのすべて2017
- Author(s)
  坂井健二、山田正仁、玉岡　晃
- Total Pages
  264
- Publisher
  医歯薬出版
- ISBN
  9784263731758
- Data Source
  KAKENHI-PROJECT-15K15336
[Book] 別冊「医学のあゆみ」アミロイドーシスの最新情報2017
- Author(s)
  坂井健二、山田正仁
- Total Pages
  160
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-15K15336
[Journal Article] Familial idiopathic basal ganglia calcification with a heterozygous missense variant (c.902C>T/p.P307L) in SLC20A2 showing widespread cerebrovascular lesions2022
- Author(s)
  Sakai K, Ishida C, Hayashi K, Tsuji N, Kannon T, Hosomichi K, Takei N, Kakita A, Tajima A, Yamada M
- Journal Title
  
  Neuropathology
  
  Volume: 42 Issue: 2 Pages: 126-133
- DOI
  10.1111/neup.12781
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07958, KAKENHI-PROJECT-20K21705, KAKENHI-PUBLICLY-21H00342
[Journal Article] 脳アミロイドアンギオパチー：最近のトピックス2022
- Author(s)
  坂井健二
- Journal Title
  
  老年期認知症会誌
  
  Volume: in press
- Open Access
- Data Source
  KAKENHI-PROJECT-19K07958
[Journal Article] Extracellular vesicles contribute to the metabolism of transthyretin amyloid in hereditary transthyretin amyloidosis2022
- Author(s)
  Yamaguchi H, Kawahara H, Kodera N, Kumaki A, Tada Y, Sakai K, Ono K, Yamada M, Hanayama R
- Journal Title
  
  Front Mol Biosci
  
  Volume: 9 Pages: 839917-839917
- DOI
  10.3389/fmolb.2022.839917
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07958, KAKENHI-PROJECT-19K22578, KAKENHI-PROJECT-20H00327, KAKENHI-PROJECT-19H03433
[Journal Article] 脳アミロイドアンギオパチー：最近のトピックス2022
- Author(s)
  坂井健二
- Journal Title
  
  老年期認知症会誌
  
  Volume: -
- Data Source
  KAKENHI-PROJECT-19K22593
[Journal Article] Hypertrophic Pachymeningitis with Characteristics of Both IgG4-related Disorders and Granulomatosis with Polyangiitis2022
- Author(s)
  Mori M, Sakai K, Saito K, Nojima T, Mohri M, Matsubara K, Hayashi S, Yamada M
- Journal Title
  
  Intern. Med.
  
  Volume: 61 Issue: 12 Pages: 1903-1906
- DOI
  10.2169/internalmedicine.8550-21
- NAID
  130008119260
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2022-06-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07958
[Journal Article] Deterioration after Liver Transplantation and Transthyretin Stabilizer Administration in a Patient with ATTRv Amyloidosis with a Leu58Arg (p.Leu78Arg) <i>TTR</i> Variant2022
- Author(s)
  Hikishima S, Sakai K, Akagi A, Yamaguchi H, Shibata S, Hayashi K, Nakano H, Kanemoto M, Usui Y, Taniguchi Y, Komatsu J, Nakamura-Shindo K, Nozaki I, Hamaguchi T, Ono K, Iwasa K, Yamada M
- Journal Title
  
  Intern. Med.
  
  Volume: 61 Issue: 15 Pages: 2347-2351
- DOI
  10.2169/internalmedicine.8945-21
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2022-08-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07958
[Journal Article] Cerebral amyloid angiopathy‐related inflammation and dementia2021
- Author(s)
  Sakai Kenji、Yamada Masahito
- Journal Title
  
  Clinical and Experimental Neuroimmunology
  
  Volume: in press Issue: 2 Pages: 101-106
- DOI
  10.1111/cen3.12634
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07958, KAKENHI-PROJECT-19K22593
[Journal Article] 脳アミロイドアンギオパチー関連炎症・血管炎2021
- Author(s)
  坂井健二、山田正仁
- Journal Title
  
  BRAIN and NERVE
  
  Volume: 73 Pages: 489-495
- Data Source
  KAKENHI-PROJECT-19K22593
[Journal Article] 脳アミロイドアンギオパチー2021
- Author(s)
  坂井健二、濵口　毅、山田正仁
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 39 Pages: 132-134
- Data Source
  KAKENHI-PROJECT-19K22593
[Journal Article] Cerebrospinal fluid cytokines and metalloproteinases in cerebral amyloid angiopathy-related inflammation2021
- Author(s)
  Sakai K, Noguchi-Shinohara M, Ikeda T, Hamaguchi T, Ono K, Yamada M
- Journal Title
  
  Acta Neurol Scand
  
  Volume: 143 Issue: 4 Pages: 450-457
- DOI
  10.1111/ane.13382
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07958, KAKENHI-PROJECT-19K22593, KAKENHI-PROJECT-17H04194, KAKENHI-PROJECT-17K09795, KAKENHI-PROJECT-19K07965
[Journal Article] Effects of functional variants of vitamin C transporter genes on apolipoprotein E E4-associated risk of cognitive decline: The Nakajima study2021
- Author(s)
  Hayashi Koji、Noguchi-Shinohara Moeko、Sato Takehiro、et al.
- Journal Title
  
  PLOS ONE
  
  Volume: 16 Issue: 11 Pages: e0259663-e0259663
- DOI
  10.1371/journal.pone.0259663
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09795, KAKENHI-PROJECT-19K07958, KAKENHI-PROJECT-19H00028, KAKENHI-PROJECT-19KK0237
[Journal Article] Early selective vulnerability of the CA2 hippocampal subfield in primary age-related tauopathy2021
- Author(s)
  Walker JM, Richardson TE, Sakai K, Sano M, Schneider JA, Stein TD, Teich AF, Trojanowski JQ, Troncoso JC, Vonsattel J-P, Weintraub S, Wolk DA, Woltjer RL, Yamada M, Yu L, White CL, Crary JF
- Journal Title
  
  J Neuropathol Exp Neurol
  
  Volume: 80 Issue: 2 Pages: 102-111
- DOI
  10.1093/jnen/nlaa153
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07958
[Journal Article] Late-onset acute disseminated encephalomyelitis followed by optic neuritis without anti-myelin oligodendrocyte glycoprotein antibodies: A biopsied case report2021
- Author(s)
  Mori M, Sakai K, Tada Y, Nozaki I, Usui Y, Ichinose T, Tanaka S, Takahashi T, Nakada M, Yamada M
- Journal Title
  
  Neurol Sci
  
  Volume: 42 Issue: 11 Pages: 4731-4735
- DOI
  10.1007/s10072-021-05419-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07958
[Journal Article] Exogenous Aβ seeds induce Ab depositions in the blood vessels rather than the brain parenchyma independently of Aβ strain-specific information2021
- Author(s)
  Hamaguchi T, Kim JH, Hasegawa A, Goto R, Sakai K, Ono K, Itoh Y, Yamada M
- Journal Title
  
  Acta Neuropathol Commun
  
  Volume: 9 Issue: 1 Pages: 151-151
- DOI
  10.1186/s40478-021-01252-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07958, KAKENHI-PROJECT-19K22593, KAKENHI-PROJECT-19K07965
[Journal Article] Recovery from multidisciplinary therapy-refractory anti-NMDA receptor encephalitis after over three years of mechanical ventilation2021
- Author(s)
  Kashihara T, Nozaki I, Sakai K, Minamikawa J, Nakamura-Shindo K, Akagi A, Ozaki T, Nakano H, Shimizu A, Komatsu J, Shima K, Ikeda T, Samuraki-Yokohama M, Hamaguchi T, Iwasa K, Tanaka K, Yamada M
- Journal Title
  
  Clin Neurol Neurosurg
  
  Volume: 202 Pages: 106477-106477
- DOI
  10.1016/j.clineuro.2021.106477
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07958, KAKENHI-PROJECT-21K07541
[Journal Article] 脳アミロイドアンギオパチー関連炎症・血管炎2021
- Author(s)
  坂井健二、山田正仁
- Journal Title
  
  BRAIN NERVE
  
  Volume: 73 Pages: 489-495
- Data Source
  KAKENHI-PROJECT-19K07958
[Journal Article] 脳アミロイドアンギオパチー2021
- Author(s)
  坂井健二、濵口毅、山田正仁
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 39 Pages: 132-134
- Data Source
  KAKENHI-PROJECT-19K07958
[Journal Article] 脳アミロイドアンギオパチー関連炎症・血管炎2020
- Author(s)
  坂井健二、山田正仁
- Journal Title
  
  BRAIN NERVE
  
  Volume: in press
- Data Source
  KAKENHI-PROJECT-19K07958
[Journal Article] Characterization of “sporadic CJD” with history of neurosurgery to identify potentially iatrogenic cases.2020
- Author(s)
  Hamaguchi T, Sakai K, Kobayashi A, Kitamoto T, Ae R, Nakamura Y, Sanjo N, Arai K, Koide M, Katada F, Harada M, Murai H, Murayama S, Tsukamoto T, Mizusawa H, Yamada M.
- Journal Title
  
  Emerg Infect Dis
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04194
[Journal Article] 脳アミロイドアンギオパチー（脳アミロイド血管症）2020
- Author(s)
  坂井健二、山田正仁
- Journal Title
  
  BIO Clinica
  
  Volume: 6 Pages: 21-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04194
[Journal Article] 脳アミロイドアンギオパチー（脳アミロイド血管症）2020
- Author(s)
  坂井健二、山田正仁
- Journal Title
  
  BIO Clinica
  
  Volume: 35 Pages: 21-25
- Data Source
  KAKENHI-PROJECT-19K07958
[Journal Article] 脳アミロイドアンギオパチー（脳アミロイド血管症）2020
- Author(s)
  坂井健二、山田正仁
- Journal Title
  
  BIO Clinica
  
  Volume: 35 Pages: 21-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22593
[Journal Article] Characterization of Sporadic Creutzfeldt-Jakob Disease and History of Neurosurgery to Identify Potential Iatrogenic Cases2020
- Author(s)
  Hamaguchi Tsuyoshi、Sakai Kenji、Kobayashi Atsushi、Kitamoto Tetsuyuki、Ae Ryusuke、Nakamura Yosikazu、Sanjo Nobuo、Arai Kimihito、Koide Mizuho、Katada Fumiaki、Harada Masafumi、Murai Hiroyuki、Murayama Shigeo、Tsukamoto Tadashi、Mizusawa Hidehiro、Yamada Masahito
- Journal Title
  
  Emerging Infectious Diseases
  
  Volume: 26 Issue: 6 Pages: 1140-1146
- DOI
  10.3201/eid2606.181969
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19KK0213, KAKENHI-PROJECT-17H04194, KAKENHI-PROJECT-18H02738, KAKENHI-PROJECT-18K05963, KAKENHI-PROJECT-19K22588
[Journal Article] Nationwide survey on cerebral amyloid angiopathy in Japan.2019
- Author(s)
  Sakai K, Ueda M, Fukushima W, Tamaoka A, Shoji M, Ando Y, Yamada M.
- Journal Title
  
  Eur J Neurol.
  
  Volume: 26(12) Issue: 12 Pages: 1487-1493
- DOI
  10.1111/ene.14031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07385, KAKENHI-PROJECT-18K07502, KAKENHI-PROJECT-19K07958, KAKENHI-PROJECT-19K22593, KAKENHI-PROJECT-19H03565
[Journal Article] Cerebral hemorrhagic stroke associated with cerebral amyloid angiopathy in young adults about 3 decades after neurosurgeries in their infancy.2019
- Author(s)
  Hamaguchi T, Komatsu J, Sakai K, Noguchi-Shinohara M, Aoki S, Ikeuchi T, Yamada M
- Journal Title
  
  J Neurol Sci
  
  Volume: 399 Pages: 3-5
- DOI
  10.1016/j.jns.2019.01.051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09752, KAKENHI-PROJECT-17H04194, KAKENHI-PROJECT-17K09795, KAKENHI-PROJECT-19K07958, KAKENHI-PROJECT-19K22593
[Journal Article] Acquired cerebral amyloid angiopathy: An emerging concept2019
- Author(s)
  Yamada Masahito、Hamaguchi Tsuyoshi、Sakai Kenji
- Journal Title
  
  Prog Mol Biol Transl Sci
  
  Volume: 168 Pages: 85-95
- DOI
  10.1016/bs.pmbts.2019.05.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07958, KAKENHI-PROJECT-19K22593, KAKENHI-PROJECT-17H04194, KAKENHI-PROJECT-17K09752
[Journal Article] Cerebral amyloid angiopathy-related microbleeds and cerebrospinal fluid biomarkers in alzheimer's disease.2017
- Author(s)
  Noguchi-Shinohara M, Komatsu J, Samuraki M, Matsunari I, Ikeda T, Sakai K, Hamaguchi T, Ono K, Nakamura H, Yamada M.
- Journal Title
  
  J Alzheimers Dis
  
  Volume: 55 Issue: 3 Pages: 905-913
- DOI
  10.3233/jad-160651
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461266, KAKENHI-PROJECT-26860234, KAKENHI-PROJECT-15K15336
[Journal Article] 脳アミロイドアンギオパチー2017
- Author(s)
  坂井健二、山田正仁
- Journal Title
  
  日本医師会雑誌
  
  Volume: 146（特別号(1)）
- Data Source
  KAKENHI-PROJECT-15K15336
[Journal Article] Coexistence of transthyretin- and Aβ-type cerebral amyloid angiopathy in a patient with hereditary transthyretin V30M amyloidosis2017
- Author(s)
  Sakai K, Asakawa M, Takahashi R, Ishida C, Nakamura R, Hamaguchi T, Ono K, Iwasa K, Yamada M
- Journal Title
  
  Journal of the Neurological Sciences
  
  Volume: 381 Pages: 144-146
- DOI
  10.1016/j.jns.2017.08.3240
- NAID
  120006375106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15336
[Journal Article] Significant association of cadaveric dura mater grafting with subpial Aβ deposition and meningeal amyloid angiopathy.2016
- Author(s)
  Hamaguchi T, Taniguchi Y, Sakai K, Kitamoto T, Takao M, Murayama S, Iwasaki Y, Yoshida M, Shimizu H, Kakita A, Takahashi H, Suzuki H, Naiki H, Sanjo N, Mizusawa H, Yamada M.
- Journal Title
  
  Acta Neuropathol.
  
  Volume: 132(2) Issue: 2 Pages: 313-5
- DOI
  10.1007/s00401-016-1588-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25257506, KAKENHI-PROJECT-16H05170, KAKENHI-PROJECT-26430060, KAKENHI-PROJECT-26860234, KAKENHI-PROJECT-15K08369, KAKENHI-PROJECT-16H06277
[Journal Article] Quantification of molecular interactions between apoE, amyloid-beta (Aβ) and laminin: relevance to accumulation of Aβ in Alzheimer’s disease2016
- Author(s)
  Zekonyte J, Sakai K, Nicoll JAR, Weller RO, Carare RO
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1862 Issue: 5 Pages: 1047-1053
- DOI
  10.1016/j.bbadis.2015.08.025
- NAID
  120005661917
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860234
[Journal Article] Aβ immunotherapy for Alzheimer's disease: effects on apoE and cerebral vasculopathy2014
- Author(s)
  Kenji Sakai, Delphine Boche, Roxana Carare, David Johnston, Clive Holmes, Seth Love, James AR Nicoll
- Journal Title
  
  Acta Neuropathologica
  
  Volume: 128 Issue: 6 Pages: 777-789
- DOI
  10.1007/s00401-014-1340-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860234
[Presentation] Elimination of vascular Aβ in cerebral amyloid angiopathy-related inflammation/vasculitis2022
- Author(s)
  Sakai K, Noguchi-Shinohara M, Tanaka H, Ikeda T, Hamaguchi T, Kakita A, Yamada M, Ono K
- Organizer
  第63回日本神経学会総会
- Data Source
  KAKENHI-PROJECT-19K22593
[Presentation] アルツハイマー病における疾患修飾療法と脳アミロイドアンギオパチー2022
- Author(s)
  坂井健二、山田正仁、小野賢二郎
- Organizer
  第63回日本神経学会総会
- Data Source
  KAKENHI-PROJECT-19K07958
[Presentation] DNM2にバリアント（c.1852G>C/p.A618P）が認められた高齢発症中心核ミオパチーの1例2022
- Author(s)
  坂井健二、林幸司、斎藤良彦、兼元みずき、西野一三、山田正仁、小野賢二郎
- Organizer
  第63回日本神経病理学会総会
- Data Source
  KAKENHI-PROJECT-19K07958
[Presentation] アルツハイマー病における疾患修飾療法と脳アミロイドアンギオパチー2022
- Author(s)
  坂井健二、山田正仁、小野賢二郎
- Organizer
  第63回日本神経学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22593
[Presentation] Elimination of vascular Aβ in cerebral amyloid angiopathy-related inflammation/vasculitis2022
- Author(s)
  Sakai K, Noguchi-Shinohara M, Tanaka H, Ikeda T, Hamaguchi T, Kakita A, Yamada M, Ono K
- Organizer
  第63回日本神経学会総会
- Data Source
  KAKENHI-PROJECT-19K07958
[Presentation] 孤発性Aβ型脳アミロイドアンギオパチー2021
- Author(s)
  坂井健二、山田正仁
- Organizer
  第8回日本アミロイドーシス学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22593
[Presentation] SLC20A2遺伝子にバリアント（c.920C>T/p.P307L）が認められた特発性基底核石灰化症の1剖検例2021
- Author(s)
  坂井健二、石田千穂、林幸司、觀音隆幸、細道一善、田嶋敦、山田正仁
- Organizer
  第62回日本神経病理学会総会
- Data Source
  KAKENHI-PROJECT-19K07958
[Presentation] 孤発性Aβ型脳アミロイドアンギオパチー2021
- Author(s)
  坂井健二、山田正仁
- Organizer
  第8回日本アミロイドーシス学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07958
[Presentation] 脳アミロイドアンギオパチー関連炎症の脳関髄液における炎症関連マーカーの解析2021
- Author(s)
  坂井健二, 篠原もえ子, 池田篤平, 浜口毅, 小野賢二郎, 山田正仁
- Organizer
  第46回日本脳卒中学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07958
[Presentation] FIBGC with a novel heterozygous variant (c.902C>T/p.P307L) in SLC20A22021
- Author(s)
  Sakai K, Ishida C, Hayashi K, Kannon T, Hosomichi K, Takei N, Kakita A, Tajima A, Yamada M
- Organizer
  第40回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07958
[Presentation] Cerebrospinal fulid inflammatory markers in cerebral amyloid angiopathy-related inflammation2021
- Author(s)
  Sakai K, Noguchi-Shinohara M, Ikeda T, Hamaguchi T, Ono K, Yamada M
- Organizer
  第62回日本神経学会総会
- Data Source
  KAKENHI-PROJECT-19K07958
[Presentation] Cerebrospinal fulid inflammatory markers in cerebral amyloid angiopathy-related inflammation2021
- Author(s)
  Sakai K, Noguchi-Shinohara M, Ikeda T, Hamaguchi T, Ono K, Yamada M
- Organizer
  第62回日本神経学会総会
- Data Source
  KAKENHI-PROJECT-19K22593
[Presentation] 脳間質液の排出障害と脳アミロイドアンギオパチー2020
- Author(s)
  坂井健二、山田正仁
- Organizer
  第61回日本神経病理学会総会学術研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04194
[Presentation] 脳アミロイドアンギオパチーにおける炎症と認知症2020
- Author(s)
  坂井健二、山田正仁
- Organizer
  第32回日本神経免疫学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07958
[Presentation] 脳アミロイドアンギオパチーにおける炎症と認知症2020
- Author(s)
  坂井健二、山田正仁
- Organizer
  第32回日本神経免疫学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04194
[Presentation] 脳間質液の排出障害と脳アミロイドアンギオパチー2020
- Author(s)
  坂井健二、山田正仁
- Organizer
  第61回日本神経病理学会総会学術研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07958
[Presentation] 脳間質液の排出障害と脳アミロイドアンギオパチー2020
- Author(s)
  坂井健二、山田正仁
- Organizer
  第61回日本神経病理学会総会学術研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22593
[Presentation] 脳アミロイドアンギオパチーにおける炎症と認知症2020
- Author(s)
  坂井健二、山田正仁
- Organizer
  第32回日本神経免疫学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22593
[Presentation] CAA-related intracerebral hemorrhage in younger patients: a nationwide study in Japan2019
- Author(s)
  Sakai K, Ueda M, Fukushima W, Tamaoka A, Shoji M, Ando Y, Yamada M
- Organizer
  第60回日本神経学会総会
- Data Source
  KAKENHI-PROJECT-19K07958
[Presentation] Cerebral amyloid angiopathy-related cognitive impairment and inflammation.2019
- Author(s)
  Sakai K, Yamada M.
- Organizer
  第60回日本神経学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22593
[Presentation] 脳アミロイドアンギオパチー関連炎症と頭痛2019
- Author(s)
  坂井健二、山田正仁
- Organizer
  第47回日本頭痛学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22593
[Presentation] CAA-related intracerebral hemorrhage in younger patients: a nationwide study in Japan.2019
- Author(s)
  Sakai K, Ueda M, Fukushima W, Tamaoka A, Shoji M, Ando Y, Yamada M.
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K22593
[Presentation] 若年発症脳アミロイドアンギオパチー関連脳出血の2例2019
- Author(s)
  濵口　毅、小松潤史、坂井健二、篠原もえ子、山田正仁、青木　悟、池内　健
- Organizer
  第155回日本神経学会東海北陸地方会
- Data Source
  KAKENHI-PROJECT-19K22593
[Presentation] 脳アミロイドアンギオパチー関連炎症と頭痛2019
- Author(s)
  坂井健二、山田正仁
- Organizer
  第47回日本頭痛学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07958
[Presentation] Cerebral amyloid angiopathy-related cognitive impairment and inflammation2019
- Author(s)
  Sakai K, Yamada M
- Organizer
  第60回日本神経学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07958
[Presentation] Clinicopathological study of cerebral amyloid angiopathy-related cerebrovascular diseases in young adults about 3 decades after neurosurgeries in the early childhood.2018
- Author(s)
  Hamaguchi T, Komatsu J, Sakai K, Aoki S, Ikeuchi T, Yamada M.
- Organizer
  Asian Pacific Prion Symposium 2018（APPS2018）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04194
[Presentation] Possible human-to-human transmission of cerebral β-amyloidosis via cadaveric dura mater grafting2017
- Author(s)
  Yamada M, Hamaguchi T, Taniguchi Y, Sakai K, Kitamoto T, Takao M, Murayama S, Iwasaki Y, Yoshida M, Shimizu H, Kakita A, Takahashi H, Suzuki H, Naiki H, Sanjo N, Mizusawa H
- Organizer
  Alzheimer's Association International Conference (AAIC) 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04194
[Presentation] Cerebral amyloid angiopathy in Alzheimer's disease2017
- Author(s)
  Sakai K, Noguchi-Shinohara M, Yamada M
- Organizer
  第36回日本認知症学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-15K15336
[Presentation] Iatrogenic Creutzfeldt-Jakob disease related to dura mater grafts2017
- Author(s)
  Yamada M, Hamaguchi T, Sakai K, Noguchi-Shinohara M, Nozaki I, Taniguchi Y, Kobayashi A, Takeuchi A, Kitamoto T, Nakamura Y, Sanjo N, Tsukamoto T, Takao M, Murayama S, Iwasaki Y, Yoshida M, Shimizu H, Kakita A, Takahashi H, Suzuki H, Naiki H, Mizusawa H
- Organizer
  PRION2017
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04194
[Presentation] Aquaporin 4 and the response to Aβ immunotherapy in human Alzheimer’s disease2016
- Author(s)
  Sakai K, Boche D, Johnston D, Holmes C, Love S, Nicoll J
- Organizer
  5th International CAA Conference
- Place of Presentation
  Boston
- Year and Date
  2016-09-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860234
[Presentation] Aβ immunothreapy for Alzheimer’s disease: effects on apolipoprotein E and cerebral vasculature2015
- Author(s)
  Sakai K, Boche D, Carare R, Johnston D, Holmes C, Love S, Nicoll J
- Organizer
  7th World Congress of the International Society for Vascular Behavioural and Cognitive Disorders (Vas-Cog2015 Tokyo)
- Place of Presentation
  Tokyo Fashion Town, Tokyo
- Year and Date
  2015-09-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860234
[Presentation] Aβ immunotherapy for Alzheimer’s disease: effects on apoE and cerebral vasculopathy
- Author(s)
  Kenji Sakai, Delphine Boche, Roxana Carare, David Johnston, Clive Holmes, Seth Love, James Nicoll
- Organizer
  第55回日本神経学会総会
- Place of Presentation
  福岡県福岡市
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26860234

1. Yamada Masahito (80191336)

# of Collaborated Projects: 5 results

# of Collaborated Products: 57 results
2. 濱口毅 (70452109)

# of Collaborated Projects: 5 results

# of Collaborated Products: 17 results
3. ONO Kenjiro (70377381)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 池田篤平 (30755773)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 中山隆宏 (00532821)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 東海林幹夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 北本哲之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 篠原もえ子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sakai Kenji 坂井 健二

Research Projects

Research Products

Co-Researchers

脳アミロイドアンギオパチー関連炎症における補体の検討と治療法開発Principal Investigator

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Pathomechanistic analysis of animal model of cerebral amyloid angiopathy-related inflammationPrincipal Investigator

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Aquired cerebral amyloid angiopathy due to neurosurgery

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Study on transmission of Abeta aggregates and its prevention

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Study on transmission of sporadic cerebral amyloid angiopathy

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Pathomechanisms of cerebral amyloid angiopathy-related inflammationPrincipal Investigator

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[Book] 高血圧性以外の脳小血管病：脳アミロイドアンギオパチー、CADASIL、CARASIL、HDLS（認知症診療実践ハンドブック 改訂2版）2021

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[Book] Stroke Revisited: Pathophysiology of Stroke2020

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[Book] Stroke Revised: Pathophysiology of Stroke2020

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[Book] Stroke Revisited: Pathophysiology of Stroke2020

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[Book] 最新アミロイドーシスのすべて2017

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[Book] 別冊「医学のあゆみ」 アミロイドーシスの最新情報2017

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[Journal Article] Familial idiopathic basal ganglia calcification with a heterozygous missense variant (c.902C>T/p.P307L) in SLC20A2 showing widespread cerebrovascular lesions2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 脳アミロイドアンギオパチー：最近のトピックス2022

Sakai Kenji 坂井健二

[Book] 高血圧性以外の脳小血管病：脳アミロイドアンギオパチー、CADASIL、CARASIL、HDLS（認知症診療実践ハンドブック　改訂2版）2021

[Book] 別冊「医学のあゆみ」アミロイドーシスの最新情報2017