NAGASAKA SHINYA 永坂真也

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NAGASAKA Shinya 永坂真也

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Researcher Number	00573239
Affiliation (based on the past Project Information) *help	2016 – 2022: 日本医科大学, 医学部, 助教 2011 – 2014: 日本医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Kidney internal medicine Except Principal Investigator Respiratory organ internal medicine / Obstetrics and gynecology / Kidney internal medicine
Keywords	Principal Investigator 樹状細胞 / DC / PDCA1 / PGE2 / 腎疾患 / プロスタグランジンE2 (PGE2) / 腎局在樹状細胞 / 炎症 / 腎炎 / 免疫学 … More / Th17 / プロスタグランジンE2 / 糸球体腎炎 / 新規樹状細胞サブセット … More Except Principal Investigator サイトカイン / microRNA / miRNA / 間質性肺炎 / 平滑筋肉腫 / 病理学 / 婦人科学 / 破骨型巨細胞 / transdifferentiation / 破骨細胞化 / 未分化癌 / 脱分化癌 / 骨芽細胞化 / 破骨細胞型巨細胞 / NFATc1 / 破骨細胞分化 / RANKL / がん関連線維芽細胞 / がん / 肉腫 / 破骨細胞様巨細胞 / 肺癌 / 腎癌 / RUNX2 / 骨芽細胞分化 / 子宮平滑筋肉腫 / エクソゾーム / II型肺胞上皮 / エクソソーム / マイクロRNA / 気管支肺胞洗浄液 / 糸球体腎炎 / 壊死性糸球体腎炎 / 抗糸球体基底膜抗体病 / 壊死性半月体形成性腎炎 / NETs / 抗糸球体基底膜抗体腎炎 / 半月体形成性糸球体腎炎 / 抗好中球細胞質抗体 / ANCA関連血管炎 / ANCA関連腎炎 / ANCA / 血管新生抑制薬 / 血管新生 / multivesicular body / exosome / 肺胞上皮 Less

Uterine Leiomyosarcoma Target Factor Identification and Application
- Principal Investigator
  
  Terasaki Mika
- Project Period (FY)
  2017 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Nippon Medical School
MicroRNA and exosome in interstitial pneumonia
- Principal Investigator
  
  Kunugi Shinobu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nippon Medical School
Elucidation of pathogenesis and progression mechanisms of glomerulonephritis through prostaglandin E2-renal dendritic cell axisPrincipal Investigator
- Principal Investigator
  
  NAGASAKA Shinya
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Nippon Medical School
Immunological network in ANCA associated glomerulonephritis
- Principal Investigator
  
  SHIMIZU Akira
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Nippon Medical School
Analysis of angiogenetic factor in interstitial pneumonia
- Principal Investigator
  
  KUNUGI Shinobu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nippon Medical School
Elucidation of Pathogenic mechanisms for glomerulonephritis and therapeutic application by a newly identified dendritic cell subsetPrincipal Investigator
- Principal Investigator
  
  NAGASAKA Shinya
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Nippon Medical School

All 2018 2015 2014 2013 2012 2011 Other

All Journal Article Presentation Other

[Journal Article] Role of α1 and α2 chains of type IV collagen in early fibrotic lesions of idiopathic interstitial pneumonias and migration of lung fibroblasts.2015
- Author(s)
  Urushiyama H, Terasaki Y, Nagasaka S, Terasaki M, Kunugi S, Nagase T, Fukuda Y, Shimizu A.
- Journal Title
  
  Lab Invest
  
  Volume: 95 Issue: 8 Pages: 872-885
- DOI
  10.1038/labinvest.2015.66
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461203, KAKENHI-PROJECT-26461204, KAKENHI-PROJECT-15K19434, KAKENHI-PROJECT-23249045, KAKENHI-PROJECT-25461175
[Journal Article] Renal inflammatory changes in acute hepatic failure-associated acute kidney injury.2013
- Author(s)
  Shimizu A, Ishii E, Masuda Y, Sato A, Piao H, Kunugi S, Takahashi M, Terasaki M, Nagasaka S, Terasaki Y, Ohashi R, Morioka T, Fukuda Y.
- Journal Title
  
  Am J Nephrol.
  
  Volume: 37 Issue: 4 Pages: 378-88
- DOI
  10.1159/000348567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590873, KAKENHI-PROJECT-23591881, KAKENHI-PROJECT-23790962, KAKENHI-PROJECT-25461175
[Journal Article] Role of survivin in acute lung injury : epithelial cells of mice and humans2013
- Author(s)
  Terasaki Y, Terasaki M, Urushiyama H, Nagasaka S, Takahashi M, Kunugi S, Ishikawa A, Wakamatsu K, Kuwahara N, Miyake K, Fukuda Y.
- Journal Title
  
  Lab Invest
  
  Volume: 93(10) Pages: 1147-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591164
[Journal Article] Role of survivin in acute lung injury: epithelial cells of mice and humans.2013
- Author(s)
  Terasaki Y, Terasaki M, Urushiyama H, Nagasaka S,Kungi S, et al.
- Journal Title
  
  Lab Invest
  
  Volume: 93 Issue: 10 Pages: 1147-1163
- DOI
  10.1038/labinvest.2013.103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591164, KAKENHI-PROJECT-23591554, KAKENHI-PROJECT-24591529, KAKENHI-PROJECT-25461175
[Journal Article] Surgical technique of orthotopic liver transplantation in rats: the Kamada technique and a new splint technique for hepatic artery reconstruction.2013
- Author(s)
  Ishii E, Shimizu A, Takahashi M, Terasaki M, Kunugi S, Nagasaka S, Terasaki Y, Ohashi R, Masuda Y, Fukuda Y.
- Journal Title
  
  J Nippon Med Sch.
  
  Volume: 80(1) Pages: 4-15
- NAID
  130004147203
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/23470801
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790962
[Journal Article] Proliferative glomerulonephritis with monoclonal immunoglobulin G3κ deposits in association with parvovirus B19 infection.2012
- Author(s)
  Fujita E, Shimizu A, Kaneko T, Masuda Y, Ishihara C, Mii A, Higo S, Kajimoto Y, Kanzaki G, Nagasaka S, Iino Y, Katayama Y, Fukuda Y.
- Journal Title
  
  Hum Pathol.
  
  Volume: 43(12) Issue: 12 Pages: 2326-33
- DOI
  10.1016/j.humpath.2012.04.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790962, KAKENHI-PROJECT-24591217
[Presentation] 機能性間質を伴った卵巣腺筋腫様腫瘍2018
- Author(s)
  寺崎美佳、寺崎泰弘、川瀬里衣子、遠藤陽子、永坂真也、功刀しのぶ、清水章
- Organizer
  日本病理学会
- Data Source
  KAKENHI-PROJECT-17K11299
[Presentation] MPO-ANCA 関連血管炎モデルにおける糸球体腎炎の増悪機序2014
- Author(s)
  神崎剛, 永坂真也, 梶本雄介, 肥後清一郎, 益田幸成, 清水章
- Organizer
  日本医科大学医学会総会 (第82回)
- Place of Presentation
  日本医科大学橘桜会館
- Year and Date
  2014-09-06
- Data Source
  KAKENHI-PROJECT-24591217
[Presentation] PPARγアゴニストによるマクロファージのインフラマソーム活性化抑制効果の検討2014
- Author(s)
  庄司昴, 永坂真也, 清水章
- Organizer
  日本医科大学医学会総会 (第82回)
- Place of Presentation
  日本医科大学橘桜会館
- Year and Date
  2014-09-06
- Data Source
  KAKENHI-PROJECT-24591217
[Presentation] MPO-ANCA関連血管炎モデルにおける半月体形成と糸球体内のサイトカインの動態2013
- Author(s)
  神崎剛, 清水章, 永坂真也, 肥後清一郎, 梶本雄介, 岩下山連, 益田幸成, 福田悠
- Organizer
  日本病理学会総会（第102回）
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24591217
[Presentation] 多重染色フローサイトメトリー法を用いた各種糸球体腎炎の病態解析2013
- Author(s)
  岩堀徹也, 清水章, 永坂真也, 加藤和則, 奥村康
- Organizer
  日本腎臓学会学術総会（第56回）
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591217
[Presentation] The reactivity of renal dendritic cells for prostaglandin E22013
- Author(s)
  Shinya Nagasaka
- Organizer
  ASN Kidney Week 2013
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-25860692
[Presentation] Aberrant Activation of Neutrophils Allow ANCA to Aggravate Glomerulonephritis in Experimental Autoimmune Vasculitis2013
- Author(s)
  Kanzaki G, Nagasaka S, Kajimoto Y, Higo S, Tsuruoka K, Shimizu A
- Organizer
  ASN Kidney Week 2013
- Place of Presentation
  Atlanta
- Data Source
  KAKENHI-PROJECT-24591217
[Presentation] The reactivity of renal dendritic cells for prostaglandin E22013
- Author(s)
  Shinya Nagasaka
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25860692
[Presentation] 炎症時における腎局在樹状細胞のプロスタグランジンE2応答性の解析2013
- Author(s)
  永坂真也, 清水章, 岩堀徹, 肥後清一郎, 神崎剛, 岩下山連, 梶本雄介, 益田幸成
- Organizer
  日本腎臓学会学術総会（第56回）
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591217
[Presentation] Statin directly inhibit macrophage differentiation and activation, and provide anti-inflammatory function.2012
- Author(s)
  Shinya Nagasaka
- Organizer
  American Society of Nephrology Kidney Week 2012
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-23790962
[Presentation] Statin directly inhibit macrophage differentiation and activation, and provide anti0inflammatory function2012
- Author(s)
  Shinya Nagasaka
- Organizer
  American Society of Nephrology Kidney Week2012
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-23790962
[Presentation] スタチン存在下で分化させたマクロファージはCox-2発現が増強する2012
- Author(s)
  永坂真也
- Organizer
  第55回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790962
[Presentation] スタチン存在下で分化させたマクロファージはCox-2発現が増強する2012
- Author(s)
  永坂真也
- Organizer
  第55回日本腎臓学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790962
[Presentation] Glomerular expression of chemokines and proinflammatory cytokines in an experimental model of anti-neutrophil cytoplasmic autoantibody associated glomerulonephritis2012
- Author(s)
  Kanzaki G, Shimizu A, Nagasaka S, Higo S, Iwashia T, Masuda Y
- Organizer
  ASN Kidney Week 2012
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-24591217
[Presentation] スタチン処理マクロファージを用いた糸球体腎炎抑制効果の検討2012
- Author(s)
  永坂真也
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790962
[Presentation] スタチンはマクロファージ分化・活性化を直接抑制し、抗炎症機能を誘導する2012
- Author(s)
  永坂真也
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23790962
[Presentation] スタチン処置マクロファージを用いた糸球体腎炎抑制効果の検討2012
- Author(s)
  永坂真也
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790962
[Presentation] スタチン処理マクロファージによる糸球体腎炎に対する抗炎症効果2011
- Author(s)
  永坂真也、清水章、益田幸成、寺崎泰弘、寺崎美佳、高橋美紀子、功刀しのぶ、福田悠
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-23790962
[Presentation] スタチン処理マクロファージによる糸球体腎炎に対する抗炎症効果2011
- Author(s)
  永坂真也
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790962
[Presentation] スタチン（Atorvastatin）によるマクロファージを介した抗炎症機構の解析2011
- Author(s)
  永坂真也、清水章、藤田恵美子、寺崎美佳、高橋美紀子、功刀しのぶ、寺崎泰弘,、益田幸成、福田悠
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-23790962
[Presentation] MPO-ANCA関連血管炎モデルにおける半月体形成の進展機序
- Author(s)
  神崎剛, 永坂真也, 梶本雄介, 肥後清一郎, 益田幸成, 清水章
- Organizer
  日本病理学会総会（第103回）
- Place of Presentation
  広島国際会議場
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-24591217
[Presentation] 腎局在樹状細胞の表現型解析
- Author(s)
  永坂真也, 岩堀徹, 肥後清一郎, 神崎剛, 梶本雄介, 益田幸成, 清水章
- Organizer
  日本腎臓学会学術総会 (第57回)
- Place of Presentation
  パシピィッコ横浜
- Year and Date
  2014-07-04 – 2014-07-06
- Data Source
  KAKENHI-PROJECT-24591217
[Presentation] MPO-ANCA関連血管炎モデルにおける半月体形成の進展機序
- Author(s)
  神崎剛, 永坂真也, 肥後清一郎, 梶本雄介, 益田幸成, 清水章
- Organizer
  日本腎臓学会学術総会 (第57回)
- Place of Presentation
  パシピィッコ横浜
- Year and Date
  2014-07-04 – 2014-07-06
- Data Source
  KAKENHI-PROJECT-24591217
[Presentation] スタチン(Atorvastatin)によるマクロファージを介した抗炎症機構の解析
- Author(s)
  永坂真也
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790962
[Presentation] 腎局在樹状細胞の表現型解析 Phenotypic characterization of renal-dendritic cells
- Author(s)
  永坂真也、岩堀徹、肥後清一郎、神崎剛、梶本雄介、益田幸成、清水章
- Organizer
  第57回日本腎臓学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-07-04 – 2014-07-06
- Data Source
  KAKENHI-PROJECT-25860692
[Presentation] Enhanced glomerular neutrophil chemoattractants expression in experimental ANCA associated vasculitis
- Author(s)
  Kanzaki G, Nagasaka S, Higo S, Kajimoto Y, Nagahama K, Masuda Y, Shimizu A
- Organizer
  ASN Kidney Week 2014 (Philadelphia)
- Place of Presentation
  Pennsylvania Convention Center
- Year and Date
  2014-11-11 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-24591217
[]

1. TERASAKI Yasuhiro (50332870)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
2. KUNUGI Shinobu (30350036)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. MIYAKE Kouichi (90267211)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. TERASAKI MIKA (50372785)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. TAKAHASHI Mikiko (40516077)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. SHIMIZU Akira (00256942)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
7. MASUDA Yukinari (70173755)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
8. SEIKE MASAHIRO (30366687)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. ISHIKAWA ARIMI (40598992)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KUWAHARA NAOMI (00599011)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 福田悠 (60097037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. 漆山博和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NAGASAKA SHINYA 永坂 真也

NAGASAKA Shinya 永坂 真也

Research Projects

Research Products

Co-Researchers

Uterine Leiomyosarcoma Target Factor Identification and Application

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

MicroRNA and exosome in interstitial pneumonia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of pathogenesis and progression mechanisms of glomerulonephritis through prostaglandin E2-renal dendritic cell axisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Immunological network in ANCA associated glomerulonephritis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of angiogenetic factor in interstitial pneumonia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of Pathogenic mechanisms for glomerulonephritis and therapeutic application by a newly identified dendritic cell subsetPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Role of α1 and α2 chains of type IV collagen in early fibrotic lesions of idiopathic interstitial pneumonias and migration of lung fibroblasts.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Renal inflammatory changes in acute hepatic failure-associated acute kidney injury.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of survivin in acute lung injury : epithelial cells of mice and humans2013

Author(s)

Journal Title

Data Source

[Journal Article] Role of survivin in acute lung injury: epithelial cells of mice and humans.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Surgical technique of orthotopic liver transplantation in rats: the Kamada technique and a new splint technique for hepatic artery reconstruction.2013

Author(s)

Journal Title

NAID

URL

Data Source

[Journal Article] Proliferative glomerulonephritis with monoclonal immunoglobulin G3κ deposits in association with parvovirus B19 infection.2012

Author(s)

Journal Title

DOI

Data Source

[Presentation] 機能性間質を伴った卵巣腺筋腫様腫瘍2018

Author(s)

Organizer

Data Source

[Presentation] MPO-ANCA 関連血管炎モデルにおける糸球体腎炎の増悪機序2014

Author(s)

Organizer

Place of Presentation

Year and Date

NAGASAKA SHINYA 永坂真也

NAGASAKA Shinya 永坂真也