Kawanishi Kunio 川西邦夫

Researcher Number	00578750
Other IDs	https://orcid.org/0000-0003-3502-3467
Affiliation (Current)	2025: 昭和大学, 医学部, 教授 2025: 筑波大学, 医学医療系, 研究員
Affiliation (based on the past Project Information) *help	2024: 筑波大学, 医学医療系, 研究員 2019 – 2022: 筑波大学, 医学医療系, 助教
Review Section/Research Field	Principal Investigator Basic Section 49030:Experimental pathology-related / Basic Section 53040:Nephrology-related Except Principal Investigator Medium-sized Section 53:Organ-based internal medicine and related fields
Keywords	Principal Investigator トリプルネガティブ乳がん / 癌幹細胞 / 癌微小環境 / 腎細胞癌 / 後天性嚢胞腎 (ACKD) / 低真空走査型電子顕微鏡 / RNAseq / レクチンアレイ / ACKD / ACD-RCC … More / 糖鎖解析 / 血液透析 / 糖鎖バイオマーカー / 後天性嚢胞腎随伴性腎細胞癌 / 透析腎癌 / バイオマーカー / Kdn / シアル酸 / 後天性嚢胞腎随伴腎細胞癌 / 後天性嚢胞腎 … More Except Principal Investigator 腎骨髄連関 / 腎臓移植 / 病理学 / 糖鎖 / 発生 / 老化 / 幹細胞 / 臓器移植 / 内科 Less

癌細胞の代謝リプログラミング依存的な糖鎖修飾と癌微小環境応答の解明Principal Investigator
- Principal Investigator
  
  川西邦夫
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  University of Tsukuba
Study of the Sialic Acid Modification and Kdn Accumulation in Acquired Cystic Kidney DiseasePrincipal Investigator
- Principal Investigator
  
  Kawanishi Kunio
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  University of Tsukuba
A strategy for the rejuvenation of older donor kidney focusing the research for development, stem cell biology and kidney-bone marrow axis: The establishment of international joint research network
- Principal Investigator
  
  Usui Joichi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  University of Tsukuba

All 2023 2022 2021 2020 2019

All Journal Article Presentation Patent

[Journal Article] Evolutionary conservation of human ketodeoxynonulosonic acid production is independent of sialoglycan biosynthesis2021
- Author(s)
  Kawanishi Kunio、Saha Sudeshna、Diaz Sandra、Vaill Michael、Sasmal Aniruddha、Siddiqui Shoib S.、Choudhury Biswa、Sharma Kumar、Chen Xi、Schoenhofen Ian C.、Sato Chihiro、Kitajima Ken、Freeze Hudson H.、M?nster-K?hnel Anja、Varki Ajit
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 131 Issue: 5
- DOI
  10.1172/jci137681
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17730, KAKENHI-PROJECT-19KK0216
[Journal Article] Polyvinyl alcohol scaffolds and supplementation support 3D and sphere culturing of human cancer cell lines by reducing apoptosis and promoting cellular proliferation2021
- Author(s)
  Okita Yukari、Zheng Ling、Kawanishi Kunio、Miyoshi Hirotoshi、Yanagihara Kazuyoshi、Kato Mitsuyasu
- Journal Title
  
  Genes to Cells
  
  Volume: 26(5) Issue: 5 Pages: 336-343
- DOI
  10.1111/gtc.12843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07658, KAKENHI-PROJECT-20K20597, KAKENHI-PROJECT-19K17730, KAKENHI-PROJECT-20K16434, KAKENHI-PROJECT-18H02676
[Journal Article] Exploring the Impact of Ketodeoxynonulosonic Acid in Host-Pathogen Interactions Using Uptake and Surface Display by Nontypeable Haemophilus influenzae2021
- Author(s)
  Saha Sudeshna、Coady Alison、Sasmal Aniruddha、Kawanishi Kunio、Choudhury Biswa、Yu Hai、Sorensen Ricardo U.、Inostroza Jaime、Schoenhofen Ian C.、Chen Xi、M?nster-K?hnel Anja、Sato Chihiro、Kitajima Ken、Ram Sanjay、Nizet Victor、Varki Ajit
- Journal Title
  
  mBio
  
  Volume: 12 Issue: 1
- DOI
  10.1128/mbio.03226-20
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17730
[Journal Article] Unusual ischemic kidney injury presenting as slowly declining graft function and successful use of oral desmopressin in a kidney transplant recipient with subclinical central diabetes insipidus2021
- Author(s)
  Kaneko Shuzo、Usui Joichi、Kawanishi Kunio、Ishii Ryota、Takahashi Kazuhiro、Suzuki Hiroaki、Saito Chie、Oda Tatsuya、Nagata Michio、Yamagata Kunihiro
- Journal Title
  
  Clinical Nephrology
  
  Volume: 95 Issue: 4 Pages: 208-214
- DOI
  10.5414/cn110295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19KK0216
[Journal Article] Exploring comprehensive glycan profiles of acquired cystic kidney disease associated renal cell carcinoma to establish a new diagnostic biomarker2021
- Author(s)
  Kawanishi Kunio
- Journal Title
  
  Impact
  
  Volume: 2021 Issue: 6 Pages: 40-42
- DOI
  10.21820/23987073.2021.6.40
- Data Source
  KAKENHI-PROJECT-19K17730
[Journal Article] Dietary Neu5Ac Intervention Protects Against Atherosclerosis Associated With Human-Like Neu5Gc Loss?Brief Report2021
- Author(s)
  Kawanishi Kunio、Coker Joanna K.、Grunddal Kaare V.、Dhar Chirag、Hsiao Jason、Zengler Karsten、Varki Nissi、Varki Ajit、Gordts Philip L.S.M.
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology
  
  Volume: 41 Issue: 11 Pages: 2730-2739
- DOI
  10.1161/atvbaha.120.315280
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0216
[Journal Article] Genetic Background and Clinicopathologic Features of Adult-onset Nephronophthisis2021
- Author(s)
  Fujimaru Takuya、Kawanishi Kunio、et al.
- Journal Title
  
  Kidney International Reports
  
  Volume: 未定 Issue: 5 Pages: 1346-1354
- DOI
  10.1016/j.ekir.2021.02.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17730, KAKENHI-PROJECT-19K17699, KAKENHI-PROJECT-20K22926, KAKENHI-PROJECT-19H03556, KAKENHI-PROJECT-20H03697, KAKENHI-PROJECT-21K08249, KAKENHI-PROJECT-19H03672
[Journal Article] 後天性嚢胞腎随伴性腎細胞癌における糖鎖関連遺伝子の次世代シーケンサー解析2020
- Author(s)
  川西　邦夫, 岡谷　千晶, 長田　道夫
- Journal Title
  
  日本透析医会雑誌
  
  Volume: 35 Pages: 673-678
- Data Source
  KAKENHI-PROJECT-19K17730
[Journal Article] Tools to study and target the Siglec?sialic acid axis in cancer2020
- Author(s)
  Laubli Heinz、Kawanishi Kunio、George Vazhappilly Cijo、Matar Rachel、Merheb Maxime、Sarwar Siddiqui Shoib
- Journal Title
  
  The FEBS Journal
  
  Volume: - Issue: 21 Pages: 6206-6225
- DOI
  10.1111/febs.15647
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0216
[Journal Article] Literature review of allograft adenovirus nephritis and a case presenting as mass lesions in a transplanted kidney without symptoms of urinary tract infection or acute kidney injury2020
- Author(s)
  Watanabe Megumi、Kaneko Shuzo、Usui Joichi、Takahashi Kazuhiro、Kawanishi Kunio、Takahashi‐Kobayashi Mayumi、Shimizu Tatsuya、Ishii Ryota、Tawara Takashi、Tsunoda Ryoya、Nagai Kei、Kawamura Tetsuya、Fujita Akiko、Kai Hirayasu、Morito Naoki、Saito Chie、Oda Tatsuya、Nagata Michio、Yamagata Kunihiro
- Journal Title
  
  Transplant Infectious Disease
  
  Volume: 23 Issue: 2
- DOI
  10.1111/tid.13468
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17695, KAKENHI-PROJECT-19KK0216, KAKENHI-PROJECT-18K08230
[Journal Article] Bidirectional, non-necrotizing glomerular crescents are the critical pathology in X-linked Alport syndrome mouse model harboring nonsense mutation of human COL4A52020
- Author(s)
  Song Jiang Ying、Saga Nobuyuki、Kawanishi Kunio、Hashikami Kentaro、Takeyama Michiyasu、Nagata Michio
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 18891-18891
- DOI
  10.1038/s41598-020-76068-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17730
[Journal Article] Human species-specific loss of CMP-N-acetylneuraminic acid hydroxylase enhances atherosclerosis via intrinsic and extrinsic mechanisms2019
- Author(s)
  Kunio Kawanishi, Chirag Dhar, Raymond Do, Nissi Varki, Philip L. S. M. Gordts, Ajit Varki
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 116 Issue: 32 Pages: 16036-16045
- DOI
  10.1073/pnas.1902902116
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0216
[Patent] 腎細胞癌検出用糖タンパク質マーカー2023
- Inventor(s)
  川西邦夫・久野敦・岡谷千晶・佐藤隆・坂上弘明・梶　裕之
- Industrial Property Rights Holder
  川西邦夫・久野敦・岡谷千晶・佐藤隆・坂上弘明・梶　裕之
- Industrial Property Rights Type
  特許
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-19K17730
[Presentation] Identification of sialic acid-containing molecules to establish a new sialoglyco-biomarker for acquired cystic disease associated renal cell carcinoma (ACD-RCC)2022
- Author(s)
  Kunio Kawanishi, Chiaki Nagai-Okatani, Shinichiro Fujita, Hiroaki Sakaue, Takashi Sato, Hiroaki Kaji, Masafumi Muratani, Mitsuyasu Kato, Atsushi Kuno
- Organizer
  Sialoglyco2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17730
[Presentation] Glycopathological Profiling of Acquired Cystic Disease Associated Renal Cell Carcinoma2021
- Author(s)
  Kunio Kawanishi
- Organizer
  1st East Asia Renal Pathology Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17730
[Presentation] シアル酸生物学からみた後天性嚢胞腎随伴性腎細胞癌の新規バイオマーカー開発2021
- Author(s)
  川西邦夫
- Organizer
  第11回分子腎臓フォーラム
- Data Source
  KAKENHI-PROJECT-19K17730
[Presentation] 後天性嚢胞腎随伴性腎細胞癌における糖鎖遺伝子と糖鎖発現の網羅的解析2021
- Author(s)
  川西邦夫、岡谷千晶、藤田晋一郎、村谷匡史、佐藤隆、梶裕之、久野敦
- Organizer
  第110回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19K17730
[Presentation] Glycan profile of acquired cystic disease associated renal cell carcinoma using lectin microarray systems2020
- Author(s)
  Kunio Kawanishi
- Organizer
  the 63th Annual Meeting of the Japanese Society of Nephrology
- Data Source
  KAKENHI-PROJECT-19K17730
[Presentation] Glycopathological Profiling of Acquired Cystic Disease Associated Renal Cell Carcinoma2020
- Author(s)
  Kunio Kawanishi
- Organizer
  East Asia Renal Pathology Conference (International Travel Award 採択＞COVID-19により延期)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17730
[Presentation] シンポジウム10「透析腎癌」糖鎖解析からみえた透析腎癌の特徴2020
- Author(s)
  川西　邦夫
- Organizer
  第50回日本腎臓学会東部学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K17730
[Presentation] シンポジウム「透析腎癌」透析腎癌の糖鎖解析2020
- Author(s)
  川西邦夫
- Organizer
  第50回日本腎臓学会東部学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K17730

1. Usui Joichi (70447340)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 馬渕洋 (50424172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 山崎聡 (50625580)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 久野敦 (50302287)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. HENGPHASATPORN Kowit (90961681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 沖田結花里

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 河村哲也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kawanishi Kunio 川西 邦夫

Research Projects

Research Products

Co-Researchers

癌細胞の代謝リプログラミング依存的な糖鎖修飾と癌微小環境応答の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study of the Sialic Acid Modification and Kdn Accumulation in Acquired Cystic Kidney DiseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A strategy for the rejuvenation of older donor kidney focusing the research for development, stem cell biology and kidney-bone marrow axis: The establishment of international joint research network

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Evolutionary conservation of human ketodeoxynonulosonic acid production is independent of sialoglycan biosynthesis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Polyvinyl alcohol scaffolds and supplementation support 3D and sphere culturing of human cancer cell lines by reducing apoptosis and promoting cellular proliferation2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Exploring the Impact of Ketodeoxynonulosonic Acid in Host-Pathogen Interactions Using Uptake and Surface Display by Nontypeable Haemophilus influenzae2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Unusual ischemic kidney injury presenting as slowly declining graft function and successful use of oral desmopressin in a kidney transplant recipient with subclinical central diabetes insipidus2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Exploring comprehensive glycan profiles of acquired cystic kidney disease associated renal cell carcinoma to establish a new diagnostic biomarker2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dietary Neu5Ac Intervention Protects Against Atherosclerosis Associated With Human-Like Neu5Gc Loss?Brief Report2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genetic Background and Clinicopathologic Features of Adult-onset Nephronophthisis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 後天性嚢胞腎随伴性腎細胞癌における糖鎖関連遺伝子の次世代シーケンサー解析2020

Author(s)

Journal Title

Data Source

[Journal Article] Tools to study and target the Siglec?sialic acid axis in cancer2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Literature review of allograft adenovirus nephritis and a case presenting as mass lesions in a transplanted kidney without symptoms of urinary tract infection or acute kidney injury2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Bidirectional, non-necrotizing glomerular crescents are the critical pathology in X-linked Alport syndrome mouse model harboring nonsense mutation of human COL4A52020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Human species-specific loss of CMP-N-acetylneuraminic acid hydroxylase enhances atherosclerosis via intrinsic and extrinsic mechanisms2019

Author(s)

Journal Title

DOI

Kawanishi Kunio 川西邦夫