HIRAO Kouji 平尾功治

Researcher Number	00581399
Other IDs
Affiliation (based on the past Project Information) *help	2018 – 2020: 徳島大学, 大学院医歯薬学研究部(歯学域), 助教 2016 – 2017: 徳島大学, 大学院医歯薬学研究部(歯学系), 助教 2015: 徳島大学, 大学院医歯薬学研究部, 助教 2011 – 2014: 徳島大学, 大学病院, 助教 2011 – 2014: 徳島大学, 病院, 助教
Review Section/Research Field	Principal Investigator Conservative dentistry Except Principal Investigator Conservative dentistry / Basic Section 57030:Conservative dentistry-related
Keywords	Principal Investigator 象牙芽細胞 / 歯髄炎 / 自然免疫 / 歯髄細胞 / KN-3 / CAPE / VEGF / 石灰化 / MINCLE / alarmin … More / NOD / Toll-Like Receptor / 歯髄保護療法 / 歯髄保護 / 抗炎症作用 / カテキン … More Except Principal Investigator 象牙芽細胞 / 自然免疫 / 歯髄炎 / 細胞・組織 / 遺伝子発現 / ポリフェノール / フッ化ジアミンシリケート / 電磁波/高周波 / 高周波/電磁波 / 齲蝕 / 高周波/電磁波治療 / 在宅・訪問歯科治療 / 健康寿命 / 齲蝕治療 / 在宅・訪問歯科治 / 訪問・在宅治療 / 深在性う蝕 / 在宅・訪問診療 / 初期歯髄炎 / う蝕治療 / 受容体 / シグナル伝達経路 / 歯髄 / 細菌感染 / Mincle / 免疫学 / 歯学 / 歯髄細胞 / インターフェロンγ / VEGF / ケモカイン / シグナル伝達 / Alarmin / 免疫応答 / ミニマルインターベンション（MI） / 自然免疫応答 / 象牙質再石灰化法 / ミニマルインターベンション / 齲蝕治療法 / アンモニウムヘクサフルオロシリケート / ミニマムインターベンション Less

Elucidation of the roles in the dental pulp of the innate immune receptor, Mincle, which recognizes dead cells by bacterial infection
- Principal Investigator
  
  YUMOTO Hiromichi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  The University of Tokushima
Elucidation of odontoblasts calcification and innate immune response in early pulpitis
- Principal Investigator
  
  TAKEGAWA Daisuke
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  The University of Tokushima
Development of a new approach to the treatments in conservative dentistry based on a concept for home or visit care.
- Principal Investigator
  
  MATSUO Takashi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  The University of Tokushima
The analysis of odontoblastic mechanism via innate immune systemPrincipal Investigator
- Principal Investigator
  
  HIRAO Kouji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  The University of Tokushima
Development of novel dental pulp preservation and calcification therapies by analyzing epigenetics and post-transcriptional regulation mechanism
- Principal Investigator
  
  YUMOTO Hiromichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  The University of Tokushima
Functional analysis of Alarmin receptors in the pathogenesis of pulpitisPrincipal Investigator
- Principal Investigator
  
  HIRAO Kouji
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  The University of Tokushima
The analyses of the immune system of odontoblast in the pathogenesis of pulpitis
- Principal Investigator
  
  TAKAHASHI Kanako
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  The University of Tokushima
Development of a new comprehensive treatment for dental caries based on minimum intervention dentistry
- Principal Investigator
  
  MATSUO Takashi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  The University of Tokushima
Development of new dental pulp protection therapy by anti-inflammatory effect of catechinPrincipal Investigator
- Principal Investigator
  
  HIRAO Kouji
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  The University of Tokushima

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation Book

[Book] The roles of cytokines in periodontal disease, In Cytokines : Mechanisms, functions and abnormalities. Edt. Manjili M H2012
- Author(s)
  Yumoto H, Hirao K, Matsuo T, Miyake Y
- Total Pages
  254
- Publisher
  Nova Science Publishers, Inc. New York
- Data Source
  KAKENHI-PROJECT-23390435
[Journal Article] Caffeic acid phenethyl ester (CAPE) induces VEGF expression and production in rat odontoblastic cells2019
- Author(s)
  Hitomi Kuramoto, Kouji Hirao, Hiromichi Yumoto, Yuki Hosokawa, Tadashi Nakanishi, Daisuke Takegawa, Ayako Washio, Chiaki Kitamura, Takashi Matsuo
- Journal Title
  
  BioMed Research International
  
  Volume: 5390720 Pages: 1-12
- DOI
  10.1155/2019/5390720
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09577, KAKENHI-PROJECT-17K11709
[Journal Article] Caffeic Acid Phenethyl Ester (CAPE) Induces VEGF Expression and Production in Rat Odontoblastic Cells2019
- Author(s)
  Kuramoto H, Hirao K, Yumoto H, Hosokawa Y, Nakanishi T, Takegawa D, Washio A, Kitamura C, Matsuo T
- Journal Title
  
  BioMed Research International
  
  Volume: ID5390720
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11708
[Journal Article] The Pathogenic Factors from Oral Streptococci for Systemic Diseases2019
- Author(s)
  Hiromichi Yumoto, Katsuhiko Hirota, Kouji Hirao, Masami Ninomiya, Keiji Murakami, Hideki Fujii, Yoichiro Miyake
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 18 Pages: 1-18
- DOI
  10.3390/ijms20184571
- NAID
  120006939610
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09577, KAKENHI-PROJECT-19K10111
[Journal Article] The Roles of Odontoblasts in Dental Pulp Innate Immunity2018
- Author(s)
  Yumoto H, Hirao K, Hosokawa Y, Kuramoto H, Takegawa D, Nakanishi T, Matsuo T
- Journal Title
  
  Japanese Dental Science Review
  
  Volume: ー
- NAID
  120006550815
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K11117
[Journal Article] The roles of odontoblasts in dental pulp innate immunity2018
- Author(s)
  Yumoto Hiromichi、Hirao Kouji、Hosokawa Yuki、Kuramoto Hitomi、Takegawa Daisuke、Nakanishi Tadashi、Matsuo Takashi
- Journal Title
  
  Japanese Dental Science Review
  
  Volume: 54 Issue: 3 Pages: 105-117
- DOI
  10.1016/j.jdsr.2018.03.001
- NAID
  120006550815
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11709, KAKENHI-PROJECT-18K09577
[Journal Article] Anti-inflammatory Effects of Catechin on Rat Odontoblastic Cells (KN-3)2017
- Author(s)
  平尾功治、湯本浩通、細川由樹、蔵本　瞳、鷲尾絢子、中西　正、武川大輔、北村知昭、松尾敬志
- Journal Title
  
  The Japanese Journal of Conservative Dentistry
  
  Volume: 60 Issue: 5 Pages: 235-244
- DOI
  10.11471/shikahozon.60.235
- NAID
  130006191168
- ISSN
  0387-2343, 2188-0808
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K11115, KAKENHI-PROJECT-15K11116, KAKENHI-PROJECT-15K11117, KAKENHI-PROJECT-26293406
[Journal Article] Functional roles of NOD1 in odontoblasts on dental pulp innate immunity.2016
- Author(s)
  Hosokawa Y, Hirao K, Yumoto H, Washio A, Nakanishi T, Takegawa D, Kitamura C, Matsuo T
- Journal Title
  
  BioMed Research International
  
  Volume: 2016 Pages: 1-11
- DOI
  10.1155/2016/9325436
- NAID
  120006535016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293406, KAKENHI-PROJECT-15K20406, KAKENHI-PROJECT-15K11116, KAKENHI-PROJECT-15K11117
[Journal Article] Electromagnetic wave irradiation promotes osteoblastic cell proliferation and up-regulates growth factor via activation of the ERK1/2 and p38 MAPK pathways2015
- Author(s)
  Yumoto H, Hirao K, Tominaga T, Bando N, Takahashi K, Matsuo T
- Journal Title
  
  Cellular Physiology and Biochemistry
  
  Volume: 35 Pages: 601-605
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24592870
[Journal Article] Modulatory roles of interferon-γ through indoleamine 2, 3-dioxygenase induction in innate immune response of dental pulp cells2014
- Author(s)
  Takegawa D, Nakanishi T, Hirao K, Yumoto H, Takahashi K, Matsuo T
- Journal Title
  
  Journal of Endodontics
  
  Volume: 40 Pages: 1382-1387
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592870
[Journal Article] Effects of extracellular DNA and DNA-binding protein on the development of a Streptococcus intermedius biofilm.2013
- Author(s)
  Nur A, Hirota K, Yumoto H, Hirao K, Liu D, Takahashi K, Murakami K, Matsuo T, Shu R, and Miyake Y.
- Journal Title
  
  Journal of applied microbiology
  
  Volume: 115(1) Pages: 260-270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861803
[Journal Article] Effect of extracellular DNA and DNA-binding protein on the development of a Streptococcus intermedius biofilm.2013
- Author(s)
  Nur A, Hirota K, Yumoto H, Hirao K, Takahasi K, Murakami K, Matsuo T, Shu R, Miyake Y.
- Journal Title
  
  J Appl Microbiol
  
  Volume: 115 Pages: 260-270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390435
[Journal Article] Effect of extracellular DNA and DNA-binding protein on the development of a Streptococcus intermedius biofilm2013
- Author(s)
  Nur A, Hirota K, Yumoto H, Hirao K, Liu D, Takahashi K, Murakami K, Matsuo T, Shu R, Miyake Y
- Journal Title
  
  Journal of Applied Microbiology
  
  Volume: 115 Pages: 260-270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592870
[Journal Article] 歯髄疾患の病態と診断2013
- Author(s)
  松尾敬志, 中西正, 湯本浩通, 高橋加奈子, 平尾功治, 武川大輔
- Journal Title
  
  日本歯内療法学会雑誌
  
  Volume: ３４ Pages: 67-76
- NAID
  10031183916
- Data Source
  KAKENHI-PROJECT-24592870
[Journal Article] Effect of extracellular DNA and DNA-binding protein on the development of a Streptococcus intermedius biofilm2013
- Author(s)
  Nur A, Hirota K, Yumoto H, Hirao K, Takahasi K, Murakami K, Matsuo T, Shu R, Miyake Y
- Journal Title
  
  J Appl Microbiol
  
  Volume: 115 Pages: 260-270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390435
[Journal Article] 歯髄疾患の病態と診断2013
- Author(s)
  松尾敬志, 尾崎和美, 中西正, 湯本浩通, 高橋加奈子, 平尾功治, 武川大輔
- Journal Title
  
  日歯内療誌
  
  Volume: 34 Pages: 67-76
- NAID
  10031183916
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390435
[Journal Article] 歯髄疾患の病態と診断.2013
- Author(s)
  松尾敬志, 尾崎和美, 中西正, 湯本浩通, 高橋加奈子, 平尾功治, 武川大輔
- Journal Title
  
  日歯内療誌
  
  Volume: 34 Pages: 67-76
- NAID
  10031183916
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390435
[Journal Article] Bactericidal activity and oral pathogen inactivation by electromagnetic wave irradiation2012
- Author(s)
  Hiromichi Yumoto, Toshihiko Tominaga, Kouji Hirao, Tomoko Kimura, Kanako Takahashi, Takashi Sumitomo, Naoki Bando, Takashi Matsuo
- Journal Title
  
  Journal of Applied Microbiology
  
  Volume: (In press) Issue: 1 Pages: 181-191
- DOI
  10.1111/j.1365-2672.2012.05307.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592423, KAKENHI-PROJECT-23390435, KAKENHI-PROJECT-24592870
[Journal Article] Bactericidal activity and oral pathogen inactivation by electromagnetic wave irradiation2012
- Author(s)
  Yumoto H, Tominaga T, Hirao K, Kimura T, Takahashi K, Sumitomo T, Bando N, Matsuo T
- Journal Title
  
  Journal of Applied Microbiology
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390435
[Journal Article] 歯髄炎発症における自然免疫機構の役割と緑茶カテキンの歯髄炎抑制効果の検討2012
- Author(s)
  平尾功治
- Journal Title
  
  四国歯学会雑誌
  
  Volume: 24(2) Pages: 21-27
- NAID
  120005832451
- Data Source
  KAKENHI-PROJECT-23792177
[Journal Article] 電磁波照射の歯内療法への応用 -EMAT (Electro-Magnetic Apical Treatment)2011
- Author(s)
  坂東直樹, 富永敏彦, 湯本浩通, 住友孝史, 平尾早希, 平尾功治, 松尾敬志
- Journal Title
  
  日歯内療誌
  
  Volume: 32 Pages: 184-200
- NAID
  10029697519
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390435
[Journal Article] Roles of dental pulp fibroblasts in the recognition of bacterium-related factors and subsequent development of pulpitis2011
- Author(s)
  Nakanishi T, Takegawa D, Hirao K, Takahashi K, Yumoto H, Matsuo T
- Journal Title
  
  Jap Dent Sci Rev
  
  Volume: 47 Issue: 2 Pages: 161-166
- DOI
  10.1016/j.jdsr.2011.02.001
- NAID
  10029548123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390435, KAKENHI-PROJECT-25670821
[Presentation] NODリガンド刺激したヒト象牙芽細胞様細胞におけるインターフェロンガンマの影響2019
- Author(s)
  武川大輔, 中西正, 平尾功治, 湯本浩通, 細川由樹, 蔵本瞳, 松尾敬志
- Organizer
  日本歯科保存学会　2019年度春季学術大会(第150回)
- Data Source
  KAKENHI-PROJECT-18K09577
[Presentation] NODリガンド刺激したヒト象牙芽細胞様細胞におけるインターフェロンγの影響2019
- Author(s)
  武川大輔、中西正、平尾功治、湯本浩通、細川由樹、蔵本瞳、松尾敬志
- Organizer
  歯科保存学会2019年度春季学術大会（150回）
- Data Source
  KAKENHI-PROJECT-17K11709
[Presentation] Caffeic acid phenethyl ester (CAPE)のラット象牙芽細胞（KN-3）におけるVEGF産生誘導機序の解析2019
- Author(s)
  蔵本瞳、湯本浩通、平尾功治、細川由樹、松尾敬志
- Organizer
  第40回日本歯内療法学会学術大会
- Data Source
  KAKENHI-PROJECT-17K11708
[Presentation] ラット象牙芽細胞(KN-3)におけるVEGFの石灰化誘導作用2019
- Author(s)
  蔵本瞳, 平尾功治, 細川由樹, 武川大輔, 湯本浩通, 中西正
- Organizer
  日本歯科保存学会　2019年度秋季学術大会(第151回)
- Data Source
  KAKENHI-PROJECT-18K09577
[Presentation] ラット象牙芽細胞（KN-3）におけるVEGFの石灰化誘導作用2019
- Author(s)
  蔵本瞳、平尾功治、細川由樹、武川大輔、湯本浩通、中西正
- Organizer
  日本歯科保存学会2019年度秋季学術大会
- Data Source
  KAKENHI-PROJECT-17K11708
[Presentation] Caffeic Acid Phenetyl Ester (CAPE)のラット象牙芽細胞(KN-3)におけるVEGF産生誘導機序の解析2019
- Author(s)
  蔵本瞳, 湯本浩通, 平尾功治, 細川由樹, 松尾敬志
- Organizer
  第40回日本歯内療法学会学術大会& 第17回日韓合同歯内療法学会学術大会
- Data Source
  KAKENHI-PROJECT-18K09577
[Presentation] NODリガンド刺激したヒト象牙芽細胞様細胞におけるインターフェロンγの影響2019
- Author(s)
  武川大輔、中西正、平尾功治、湯本浩通、細川由樹、蔵本瞳、松尾敬志
- Organizer
  日本歯科保存学会2019年度春季学術大会
- Data Source
  KAKENHI-PROJECT-17K11708
[Presentation] ラット象牙芽細胞（KN-3）におけるVEGFの石灰化誘導作用2019
- Author(s)
  蔵本瞳、平尾功治、細川由樹、中西正、武川大輔、湯本浩通、松尾敬志
- Organizer
  歯科保存学会2019年度秋季学術大会（151回）
- Data Source
  KAKENHI-PROJECT-17K11709
[Presentation] 高周波電流を用いた歯周組織再生療法2019
- Author(s)
  平尾功治、湯本浩通、富永敏彦、太良尾浩生、榎本崇宏、芥川正武、池原敏孝、木内陽介
- Organizer
  生体医工学会シンポジウム
- Data Source
  KAKENHI-PROJECT-17K11708
[Presentation] Caffeic Acid Phenetyl Ester (CAPE)の象牙芽細胞と骨芽細胞におけるVEGF産生誘導機序の解析2018
- Author(s)
  蔵本瞳, 湯本浩通, 平尾功治, 細川由樹, 中西正, 武川大輔, 松尾敬志
- Organizer
  日本歯科保存学会　2018年度春季学術大会(第148回)
- Data Source
  KAKENHI-PROJECT-18K09577
[Presentation] Cafferic Acid Phenethyl Ester (CAPE) の象牙芽細胞と骨芽細胞におけるVGEF産生誘導機序の解析2018
- Author(s)
  蔵本瞳、湯本浩通、平尾功治、細川由樹、中西正、武川大輔、松尾敬志
- Organizer
  歯科保存学会2018年度春季学術大会（１４８回）
- Data Source
  KAKENHI-PROJECT-17K11709
[Presentation] Effect of high frequency electric field on growth factor of cultured osteoblasts2018
- Author(s)
  Shunsuke Yamaguchi, Masatake Akutagawa, Hiromichi Yumoto, Kouji Hirao, Takahiro Emoto, Hiroo Tarao, Toshihiko Tominaga, Toshitaka Ikehara and Yohsuke Kinouchi
- Organizer
  2018 The Joint Annual Meeting of the Bioelectromagnetics Society and the European BioElectromagnetics Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11708
[Presentation] Interferon-gamma modulates the innate immune response in odontoblast-like cells2017
- Author(s)
  Daisuke Takegawa, Tadashi Nakanishi, Kouji Hirao, Hiromichi Yumoto, Yuki Hosokawa, Takashi Matsuo
- Organizer
  95th General Session & Exhibition of the International Association for Dental Research
- Place of Presentation
  San Francisco (USA)
- Year and Date
  2017-03-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11117
[Presentation] プロポリス生理活性物質(CAPE; Caffeic Acid Phenetyl Ester)を用いた新規覆髄材の開発2017
- Author(s)
  平尾功治, 蔵本瞳, 湯本浩通, 細川由樹, 松尾敬志
- Organizer
  第17回西日本歯内療法学会研修会
- Data Source
  KAKENHI-PROJECT-15K11117
[Presentation] ヒト歯髄組織ならびにラット象牙芽細胞(KN-3)におけるMincle発現と象牙芽細胞での機能解析,2017
- Author(s)
  平尾功治, 湯本浩通, 細川由樹, 蔵本瞳, 松尾敬志
- Organizer
  第38回日本歯内療法学会学術大会
- Data Source
  KAKENHI-PROJECT-15K11116
[Presentation] Effect of Interleukin-17A on CCL20 Production From Odontoblast-like Cells2017
- Author(s)
  Tadashi Nakanishi, Kouji Hirao, Hiromichi Yumoto, Yuki Hosokawa, Takashi Matsuo
- Organizer
  The 95th General Session & Exhibition of the IADR
- Place of Presentation
  サンフランシスコ、アメリカ
- Year and Date
  2017-03-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11116
[Presentation] Effect of Interleukin-17 on CCL20 production from odontoblasti-like cells2017
- Author(s)
  Tadashi Nakanishi, Daisuke Takegawa, Kouji Hirao, Hiromichi Yumoto, Yuki Hosokawa, Takashi Matsuo
- Organizer
  95th General Session & Exhibition of the International Association for Dental Research
- Place of Presentation
  San Francisco (USA)
- Year and Date
  2017-03-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11117
[Presentation] Anti-Inflammatory Effects of Polyphenols on Rat Odontblastic Cells2017
- Author(s)
  Yuki Hosokawa, Hiromichi Yumoto, Kouji Hirao, Hitomi Kuramoto, Tadashi Nakanishi, Daisuke Takegawa, Takashi Matsuo
- Organizer
  The 95th General Session & Exhibition of the IADR
- Place of Presentation
  サンフランシスコ、アメリカ
- Year and Date
  2017-03-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11116
[Presentation] Caffeic Acid Phenethyl Ester (CAPE) のラット象牙芽細胞 (KN-3) におけるVEGF産生に与える影響2017
- Author(s)
  蔵本瞳、湯本浩通、平尾功治、細川由樹、中西正、武川大輔、松尾敬志
- Organizer
  第146回日本歯科保存学会
- Data Source
  KAKENHI-PROJECT-17K11709
[Presentation] Caffeic Acid Phenethyl Ester (CAPE)のラット象牙芽細胞(KN-3)におけるVEGF産生に与える影響2017
- Author(s)
  蔵本瞳, 湯本浩通, 平尾功治, 細川由樹, 中西正, 武川大輔, 松尾敬志
- Organizer
  日本歯科保存学会　2017年度春季学術大会(第146回)
- Data Source
  KAKENHI-PROJECT-15K11117
[Presentation] Caffeic Acid Phenethyl Ester (CAPE)のラット象牙芽細胞(KN-3)におけるVEGF産生に与える影響2017
- Author(s)
  蔵本瞳, 湯本浩通, 平尾功治, 細川由樹, 中西正, 武川大輔, 松尾敬志
- Organizer
  日本歯科保存学会2017年度春季学術大会(第146回)
- Data Source
  KAKENHI-PROJECT-15K11116
[Presentation] Anti-inflammatory effects of polyphenols on rat odontoblastic cells2017
- Author(s)
  Yuki Hosokawa, Hiromichi Yumoto, Kouji Hirao, Hitomi Kuramoto, Tadashi Nakanishi, Daisuke Takegawa, Takashi Matsuo
- Organizer
  95th General Session & Exhibition of the International Association for Dental Research
- Place of Presentation
  San Francisco (USA)
- Year and Date
  2017-03-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11117
[Presentation] Interferon-γ Modulates the Innate Immune Response in Odontoblast-like Cells2017
- Author(s)
  Daisuke Takegawa, Tadashi Nakanishi, Kouji Hirao, Hiromichi Yumoto, Yuki Hosokawa, Takashi Matsuo
- Organizer
  The 95th General Session & Exhibition of the IADR
- Place of Presentation
  サンフランシスコ、アメリカ
- Year and Date
  2017-03-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11116
[Presentation] ラット象牙芽細胞様細胞(KN-3)に対するポリフェノールの炎症抑制効果2016
- Author(s)
  細川由樹, 湯本浩通, 平尾功治, 松尾敬志
- Organizer
  第37回日本歯内療法学会学術大会
- Place of Presentation
  ウインク愛知（愛知県名古屋市）
- Year and Date
  2016-07-23
- Data Source
  KAKENHI-PROJECT-15K11116
[Presentation] ラット象牙芽細胞様細胞(KN-3)に対するポリフェノールの炎症抑制効果2016
- Author(s)
  細川由樹, 湯本浩通, 平尾功治, 松尾敬志
- Organizer
  第37回日本歯内療法学会学術大会
- Place of Presentation
  ウインクあいち（愛知県産業労働センター）（愛知県名古屋市）
- Year and Date
  2016-07-23
- Data Source
  KAKENHI-PROJECT-15K11117
[Presentation] ラット象牙芽細胞(KN-3)の自然免疫反応におけるシグナル伝達経路の解析2015
- Author(s)
  平尾功治, 湯本浩通, 細川由樹, 中西正, 武川大輔, 松尾敬志
- Organizer
  日本歯科保存学会2015年度春季学術大会(第142回)
- Place of Presentation
  北九州国際会議場（福岡県北九州市）
- Year and Date
  2015-06-25
- Data Source
  KAKENHI-PROJECT-15K11116
[Presentation] Interleukin-17がラット象牙芽細胞様細胞(KN-3)のCCL20産生に及ぼす影響2015
- Author(s)
  中西正, 武川大輔, 平尾功治, 湯本浩通, 細川由樹, 松尾敬志
- Organizer
  日本歯科保存学会　2015年度秋季学術大会(第143回)
- Place of Presentation
  文京シビックホール（東京都文京区）
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-15K11117
[Presentation] 象牙芽細胞が有するMincleを介した視細胞認識機構とその歯髄炎症反応における役割2015
- Author(s)
  細川由樹, 湯本浩通, 平尾功治, 中西正, 武川大輔, 松尾敬志
- Organizer
  日本歯科保存学会 2015年度秋季学術大会(第143回)
- Place of Presentation
  文京シビックホール（東京都文京区）
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-15K11116
[Presentation] ラット象牙芽細胞(KN-3)の自然免疫反応におけるシグナル伝達経路の解析2015
- Author(s)
  平尾功治, 湯本浩通, 細川由樹, 中西　正, 武川大輔, 松尾敬志
- Organizer
  日本歯科保存学会　2015年度春季学術大会(第142回)
- Place of Presentation
  西日本総合展示場・北九州国際会議場（福岡県北九州市）
- Year and Date
  2015-06-25
- Data Source
  KAKENHI-PROJECT-15K11117
[Presentation] 象牙芽細胞が有するMincleを介した視細胞認識機構とその歯髄炎症反応における役割2015
- Author(s)
  細川由樹, 湯本浩通, 平尾功治, 中西　正, 武川大輔, 松尾敬志
- Organizer
  日本歯科保存学会　2015年度秋季学術大会(第143回)
- Place of Presentation
  文京シビックホール（東京都文京区）
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-15K11117
[Presentation] ラット象牙芽細胞(KN-3)に対するカテキンとカフェイン酸の抗炎症作用2015
- Author(s)
  細川由樹, 湯本浩通, 平尾功治, 中西正, 武川大輔, 松尾敬志
- Organizer
  日本歯科保存学会2015年度春季学術大会(第142回)
- Place of Presentation
  北九州国際会議場（福岡県北九州市）
- Year and Date
  2015-06-25
- Data Source
  KAKENHI-PROJECT-15K11116
[Presentation] Interleukin-17がラット象牙芽細胞様細胞(KN-3)のCCL20産生に及ぼす影響2015
- Author(s)
  中西正, 武川大輔, 平尾功治, 湯本浩通, 細川由樹, 松尾敬志
- Organizer
  日本歯科保存学会 2015年度秋季学術大会(第143回)
- Place of Presentation
  文京シビックホール（東京都文京区）
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-15K11116
[Presentation] ラット象牙芽細胞(KN-3)に対するカテキンとカフェイン酸の抗炎症作用2015
- Author(s)
  細川由樹, 湯本浩通, 平尾功治, 中西　正, 武川大輔, 松尾敬志
- Organizer
  日本歯科保存学会　2015年度春季学術大会(第142回)
- Place of Presentation
  西日本総合展示場・北九州国際会議場（福岡県北九州市）
- Year and Date
  2015-06-25
- Data Source
  KAKENHI-PROJECT-15K11117
[Presentation] Functional Roles of NOD1 in Odontoblasts on Pulp Innate Immunity2014
- Author(s)
  Kouji Hirao, Hiromichi Yumoto, Yuki Hosokawa, Chihiro Shinohara and Takashi Matsuo
- Organizer
  第62回国際歯科研究学会　日本部会総会・学術大会
- Place of Presentation
  KKRホテル大阪（大阪府・大阪市）
- Year and Date
  2014-12-05
- Data Source
  KAKENHI-PROJECT-25861803
[Presentation] ラット象牙芽細胞様細胞(KN3)における細菌関連病原因子刺激に対する自然免疫反応の解析2014
- Author(s)
  平尾功治, 湯本浩通, 中西正, 篠原千尋, 高橋加奈子, 武川大輔, 細川由樹, 松尾敬志
- Organizer
  日本歯科保存学会2014年度春学術大会
- Place of Presentation
  滋賀県立芸術劇場（滋賀県・大津市）
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PROJECT-25861803
[Presentation] 細菌関連病原因子によるラット象牙芽細胞の自然免疫機構の解析2014
- Author(s)
  平尾功治, 湯本浩通
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  タワーホール船堀(東京都)
- Data Source
  KAKENHI-PROJECT-23390435
[Presentation] 細菌関連病原因子によるラット象牙芽細胞の自然免疫機構の解析2014
- Author(s)
  平尾功治, 湯本浩通.
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  タワーホール船堀, 東京
- Data Source
  KAKENHI-PROJECT-23390435
[Presentation] Pathologic roles of Streptococcal histon-like protein in microbial infection2013
- Author(s)
  Yumoto H, Hirota K, Hirao K, Murakami K, Miyake Y, Matsuo T
- Organizer
  The 15th Joint Scientific meeting of JSCD-KACD
- Place of Presentation
  The K hotel & resort, The K Hotel & Resort, (Gyeongju, Korea)
- Year and Date
  2013-11-23
- Data Source
  KAKENHI-PROJECT-23390435
[Presentation] Homologous and heterologous extracellular DNAs affect Pseudomonas aeruginosa to produce more pyocyanin without inducing bacterial growth2013
- Author(s)
  Asikin Nur, Katsuhiko Hirota, Hiromichi Yumoto, Kouji Hirao, Kanako Takahashi, Keiji Murakami and Yoichiro Miyake
- Organizer
  第66回日本細菌学会中国・四国支部総会
- Place of Presentation
  広島国際大学メディアホール（広島県）
- Data Source
  KAKENHI-PROJECT-24592870
[Presentation] Prostaglandin F2a regulates cytokine expression in dental pulp cells2013
- Author(s)
  Nakanishi T, Takegawa D, Hirao K, Yumoto H, Takahashi K, Matsuo T
- Organizer
  91st General Session & Exhibition of the IADR
- Place of Presentation
  Seattle USA
- Data Source
  KAKENHI-PROJECT-23390435
[Presentation] Streptococcus intermediusヒストン様タンパク質のPAMPSとしての解析2013
- Author(s)
  弘田克彦, 湯本浩通, 村上圭史, 平尾功治, 高橋加奈子, 松尾敬志, 三宅洋一郎
- Organizer
  第22回Lancefieldレンサ球菌研究会＆第45回レンサ球菌感染症研究会
- Place of Presentation
  ホテル島根イン青山パインコートI・II（東京都）
- Data Source
  KAKENHI-PROJECT-24592870
[Presentation] 高周波・電磁波照射の歯内療法への応用 -基礎実験~臨床症例-2013
- Author(s)
  湯本浩通, 富永敏彦, 坂東直樹, 平尾功治, 松尾敬志
- Organizer
  第13回日本歯内療法学会西日本支部会研修会
- Place of Presentation
  大阪歯科大学附属病院(大阪府)
- Year and Date
  2013-07-07
- Data Source
  KAKENHI-PROJECT-23390435
[Presentation] Interferon-g modulates the innate immune response of dental pulp cells2013
- Author(s)
  Takegawa D, Nakanishi T, Hirao K, Yumoto H, Takahashi K, Matsuo T
- Organizer
  91st General Session & Exhibition of the IADR
- Place of Presentation
  Seattle USA
- Data Source
  KAKENHI-PROJECT-23390435
[Presentation] イグサ抽出液のう蝕および歯周病予防効果の評価2013
- Author(s)
  湯本浩通, 平尾功治, 松尾敬志
- Organizer
  第139回日本歯科保存学会2013年度秋期学術大会
- Place of Presentation
  秋田県総合生活文化会館(秋田県)
- Data Source
  KAKENHI-PROJECT-23390435
[Presentation] Electro-Magnetic Apical Treatment -囊胞性疾患に対する対応-2013
- Author(s)
  富永敏彦, 湯本浩通, 坂東直樹, 平尾功治, 平尾早希, 加古晋也, 前田やよい, 山口由美子, 高比良一輝, 松尾敬志
- Organizer
  第138回日本歯科保存学会2013年度春期学術大会
- Place of Presentation
  福岡国際会議場(福岡県)
- Data Source
  KAKENHI-PROJECT-23390435
[Presentation] グサ抽出液のう蝕および歯周病予防効果の評価.2013
- Author(s)
  湯本浩通, 平尾功治, 松尾敬志.
- Organizer
  139回日本歯科保存学会2013年度秋期学術大会.
- Place of Presentation
  秋田県総合生活文化会館, 秋田
- Data Source
  KAKENHI-PROJECT-23390435
[Presentation] Grobal gene analysis in monocytes stimulated with Streptococcul histone-like protein2012
- Author(s)
  K Hirao et al
- Organizer
  International association for dental reseach general session
- Place of Presentation
  Convention center（Brazil）
- Data Source
  KAKENHI-PROJECT-24592870
[Presentation] Global gene analysis in monocytes stimulated with Streptococal histon-like protein2012
- Author(s)
  Hirao K
- Organizer
  90th General Session & Exhibition of the International Association for Dental Research
- Place of Presentation
  CECONFI Convention Center (Brazil)
- Data Source
  KAKENHI-PROJECT-23390435
[Presentation] 電磁波照射による骨芽細胞の活性化とGrowth Factorの発現誘導2012
- Author(s)
  湯本浩通, 富永敏彦, 平尾功治, 松尾敬志
- Organizer
  第10回日本再生歯科医学会学術大会
- Place of Presentation
  ニチイ学館神戸ポートアイランドセンター(兵庫県)
- Data Source
  KAKENHI-PROJECT-23390435
[Presentation] Prostaglandin F2a は歯髄細胞における炎症メディエーター発現を調節する2012
- Author(s)
  中西正, 武川大輔, 平尾功治, 湯本浩通, 高橋加奈子, 松尾敬志
- Organizer
  第136回日本歯科保存学会2012年度春期学術大会
- Place of Presentation
  沖縄コンベンションセンター(沖縄県)
- Data Source
  KAKENHI-PROJECT-23390435
[Presentation] Signaling pathways and gene activate by electro-magnetic-wave in osteoblastic cells2012
- Author(s)
  Yumoto H, Tominaga T, Hirao K, Bando T, Sumitomo T, Takahashi K, Matsuo T
- Organizer
  90th General Session & Exhibition of the IADR
- Place of Presentation
  Iguacu Falls, (Brazil)
- Data Source
  KAKENHI-PROJECT-23390435
[Presentation] Grobal Gene Analysis in Monocytes Stimulated with Streptococcal Histon-Like Protein2012
- Author(s)
  K Hirao
- Organizer
  90th Genaral Session & Exhibition of the International Association of Dental Research
- Place of Presentation
  Foz do Iguazu Convention Center、Iguazu falls (Brazil)
- Year and Date
  2012-06-21
- Data Source
  KAKENHI-PROJECT-23792177
[Presentation] ヒト歯髄線維芽細胞の自然免疫応答に対するインターフェロン・の影響2011
- Author(s)
  武川大輔, 中西正, 平尾功治, 湯本浩通, 高橋加奈子, 松尾敬志
- Organizer
  第134回日本歯科保存学会2011年度春期学術大会
- Place of Presentation
  東京ベイ舞浜ホテルクラブリゾート(千葉県)
- Data Source
  KAKENHI-PROJECT-23390435
[Presentation] 高周波・電磁波照射による骨芽細胞のGrowth Factor の発現・産生誘導2011
- Author(s)
  湯本浩通, 富永敏彦, 平尾功治, 高橋加奈子, 松尾敬志
- Organizer
  第135回日本歯科保存学会2011年度秋期学術大会
- Place of Presentation
  大阪国際交流センター(大阪府)
- Data Source
  KAKENHI-PROJECT-23390435
[Presentation] 電磁波根尖治療法EMAT(Electro-Magnetic Apical Treatment)を行った1例2011
- Author(s)
  住友孝史, 富永敏彦, 坂東直樹, 平尾早希, 加古晋也, 湯本浩通, 松尾敬志
- Organizer
  第32回日本歯内療法学会学術大会
- Place of Presentation
  全日空長崎ホテル(長崎県)
- Data Source
  KAKENHI-PROJECT-23390435
[Presentation] 高周波・電磁波照射を歯内療法に応用した症例2011
- Author(s)
  湯本浩通, 富永敏彦, 柴田眞吾, 武川大輔, 高橋加奈子, 木村智子, 平尾功治, 松尾敬志
- Organizer
  第134回日本歯科保存学会2011年度春期学術大会
- Place of Presentation
  東京ベイ舞浜ホテルクラブリゾート(千葉県)
- Data Source
  KAKENHI-PROJECT-23390435
[Presentation] Effect of extracellular DNA on pyocyanin production from Pseudomonas aeruginosa
- Author(s)
  Asikin Nur, Katsuhiko Hirota, Hiromichi Yumoto, Kouji Hirao, Kanako Takahashi, Keiji Murakami, Takashi Matsuo and Yoichiro Miyake
- Organizer
  第27回Bacterial Adherence&biofilm学術集会
- Place of Presentation
  東京ガーデンパレス（東京都）
- Data Source
  KAKENHI-PROJECT-24592870
[Presentation] Pathogenic roles of Streptococcal histon-like protein in microbial infection
- Author(s)
  Hiromichi Yumoto, Katsuhiko Hirota, Kouji Hirao, Keiji Murakami, Yoichiro Miyake, Takashi Matsuo
- Organizer
  The 13th Joint Sceintific Meeting of JSCD-KACJ
- Place of Presentation
  The K Hotel & Resort, Gyeongju, Korea
- Data Source
  KAKENHI-PROJECT-25861803
[Presentation] 細菌関連病原因子によるラット象牙芽細胞の自然免疫反応の解析
- Author(s)
  平尾　功治、湯本　浩通
- Organizer
  第87回　日本細菌学会総会
- Place of Presentation
  タワーホール船堀（東京都）
- Data Source
  KAKENHI-PROJECT-25861803
[Presentation] イグサ抽出液のオーラルヘルスケア製品への応用に関する研究
- Author(s)
  細川由樹, 湯本浩通, 平尾功治, 高橋加奈子, 松尾敬志
- Organizer
  第141回　日本歯科保存学会
- Place of Presentation
  山形県山形市　山形テルサ
- Year and Date
  2014-10-30 – 2014-10-31
- Data Source
  KAKENHI-PROJECT-24592870
[Presentation] Global Gene Analysis in Monocytes Stimulated with Streptococcal Histon-Like Protein
- Author(s)
  K Hirao
- Organizer
  90th General Session & Exhibition of the Internatinal Association for Dental Research
- Place of Presentation
  Iguazu falls (Brazil)
- Data Source
  KAKENHI-PROJECT-23792177
[Presentation] 高周波・電磁波照射の歯内療法への応用 ; 基礎実験～臨床症例
- Author(s)
  湯本浩通, 富永敏彦, 坂東直樹, 平尾功治, 松尾敬志.
- Organizer
  第13回日本歯内療法学会西日本支部会研修会
- Place of Presentation
  大阪歯科大学附属病院, 大阪
- Data Source
  KAKENHI-PROJECT-23390435
[Presentation] ラット象牙芽細胞様細胞（KN3）における細菌関連病原因子刺激に対する自然免疫反応の解析
- Author(s)
  平尾功治, 湯本浩通, 中西正, 篠原千尋, 高橋加奈子, 武川大輔, 細川由樹, 松尾敬志
- Organizer
  第140回　日本歯科保存学会
- Place of Presentation
  滋賀県立芸術劇場びわ湖ホール(滋賀県大津市）
- Year and Date
  2014-06-19 – 2014-06-20
- Data Source
  KAKENHI-PROJECT-24592870

1. YUMOTO Hiromichi (60284303)

# of Collaborated Projects: 6 results

# of Collaborated Products: 68 results
2. NAKANISHI Tadashi (00217770)

# of Collaborated Projects: 5 results

# of Collaborated Products: 32 results
3. MATSUO Takashi (30173800)

# of Collaborated Projects: 3 results

# of Collaborated Products: 38 results
4. SUGE Toshiyuki (60243713)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. TAKAHASHI Kanako (80403715)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
6. TAKEGAWA Daisuke (10632664)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
7. 木戸淳一 (10195315)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 稲垣裕司 (50380019)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 二宮雅美 (10291494)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. WASHIO Ayako

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 北村知昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 二宮政美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HIRAO Kouji 平尾 功治

Research Projects

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Elucidation of the roles in the dental pulp of the innate immune receptor, Mincle, which recognizes dead cells by bacterial infection

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Elucidation of odontoblasts calcification and innate immune response in early pulpitis

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Development of a new approach to the treatments in conservative dentistry based on a concept for home or visit care.

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The analysis of odontoblastic mechanism via innate immune systemPrincipal Investigator

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Development of novel dental pulp preservation and calcification therapies by analyzing epigenetics and post-transcriptional regulation mechanism

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Functional analysis of Alarmin receptors in the pathogenesis of pulpitisPrincipal Investigator

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The analyses of the immune system of odontoblast in the pathogenesis of pulpitis

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Development of a new comprehensive treatment for dental caries based on minimum intervention dentistry

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Development of new dental pulp protection therapy by anti-inflammatory effect of catechinPrincipal Investigator

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[Book] The roles of cytokines in periodontal disease, In Cytokines : Mechanisms, functions and abnormalities. Edt. Manjili M H2012

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[Journal Article] Caffeic acid phenethyl ester (CAPE) induces VEGF expression and production in rat odontoblastic cells2019

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[Journal Article] Caffeic Acid Phenethyl Ester (CAPE) Induces VEGF Expression and Production in Rat Odontoblastic Cells2019

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[Journal Article] The Pathogenic Factors from Oral Streptococci for Systemic Diseases2019

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[Journal Article] The Roles of Odontoblasts in Dental Pulp Innate Immunity2018

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HIRAO Kouji 平尾功治