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Oikawa Naoto  及川 尚人

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OIKAWA Naoto  及川 尚人

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Researcher Number 00583585
Other IDs
Affiliation (Current) 2025: 北海道大学, 遺伝子病制御研究所, 助教
Affiliation (based on the past Project Information) *help 2022 – 2025: 北海道大学, 遺伝子病制御研究所, 助教
2011: 独立行政法人国立長寿医療研究センター, 認知症先進医療開発センター治療薬探索研究部, 流動研究員
2010 – 2011: 独立行政法人国立長寿医療研究センター, 認知症先進医療開発センター・治療薬探索研究部, 流動研究員
Review Section/Research Field
Principal Investigator
Basic Section 51030:Pathophysiologic neuroscience-related / Neurology
Keywords
Principal Investigator
神経変性 / プレセニリン / アルツハイマー病 / 認知症 / 細胞老化 / 脂質 / 神経細胞 / NPC1 / コレステロール / γ-セクレターゼ … More / 膜脂質 / アミロイドβ蛋白 / アミロイドβプロテイン / γセレクターゼ / ガングリオシド / アミロイド / アミロイドβプロテイ / γセクレターゼ / 神経変性疾患 Less
  • Research Projects

    (3 results)
  • Research Products

    (5 results)
  • Co-Researchers

    (1 People)
  •  老年期神経変性における細胞老化関連因子の役割Principal Investigator

    • Principal Investigator
      及川 尚人
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 51030:Pathophysiologic neuroscience-related
    • Research Institution
      Hokkaido University
  •  Effect of Alzheimer associated presenilin dysfunction on cholesterol metabolism in human neuronPrincipal Investigator

    • Principal Investigator
      及川 尚人
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 51030:Pathophysiologic neuroscience-related
    • Research Institution
      Hokkaido University
  •  The impact of clinical presenilin mutations on amyloid formation in the brains of familial Alzheimer diseasePrincipal Investigator

    • Principal Investigator
      OIKAWA Naoto
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Neurology
    • Research Institution
      National Center for Geriatrics and Gerontology

All 2024 2022 2012 2011

All Journal Article Presentation

  • [Journal Article] Presenilin Deficiency Results in Cellular Cholesterol Accumulation by Impairment of Protein Glycosylation and NPC1 Function2024

    • Author(s)
      Fabiano Marietta、Oikawa Naoto、Kerksiek Anja、Furukawa Jun-ichi、Yagi Hirokazu、Kato Koichi、Schweizer Ulrich、Annaert Wim、Kang Jongkyun、Shen Jie、Lutjohann Dieter、Walter Jochen
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 25 Issue: 10 Pages: 5417-5417

    • DOI

      10.3390/ijms25105417

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-23H03834, KAKENHI-PLANNED-23H03838, KAKENHI-PROJECT-23K21358, KAKENHI-PROJECT-23K24759, KAKENHI-PROJECT-22K07364, KAKENHI-PROJECT-22K08605
  • [Presentation] Presenilin deficiency increases cholesterol by impaired protein glycosylation2022

    • Author(s)
      及川 尚人
    • Organizer
      第41回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K07364
  • [Presentation] Suppression ofγ-secretase activity increases ganglioside levels at neuritic terminals of differentiated PC122012

    • Author(s)
      Naoto Oikawa, Miho Goto, Kazutaka Ikeda, Ryo Taguchi, Katsuhiko Yanagisawa
    • Organizer
      ASBMB annual meeting
    • Place of Presentation
      San Diego
    • Year and Date
      2012-04-23
    • Data Source
      KAKENHI-PROJECT-22890251
  • [Presentation] Inhibition ofγ-secretase activity increases ganglioside levels at neuritic terminals of differentiated PC122011

    • Author(s)
      Naoto Oikawa, Miho Goto, Kazutaka Ikeda, Ryo Taguchi, Katsuhiko Yanagisawa
    • Organizer
      3rd international symposium of Nagoya university global COE
    • Place of Presentation
      Nagoya
    • Year and Date
      2011-12-09
    • Data Source
      KAKENHI-PROJECT-22890251
  • [Presentation] Inhibition of γ-secretase activity increases ganglioside levels at neuntic terminals of differentiated PC122011

    • Author(s)
      及川尚人
    • Organizer
      名古屋大学グローバルCOE第3回国際シンポジウム
    • Place of Presentation
      名古屋ミッドランドスクエア5階・ミッドランドホール
    • Year and Date
      2011-12-09
    • Data Source
      KAKENHI-PROJECT-22890251
  • 1.  YAGI Hirokazu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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