SEKINE Yusuke 関根悠介

Researcher Number	00583981
Other IDs	https://orcid.org/0000-0003-0345-1416
Affiliation (based on the past Project Information) *help	2012: 東京大学, 大学院・薬学系研究科, 助教 2011: 東京大学, 大学院・薬学研究科, 特任研究員 2010 – 2011: 東京大学, 大学院・薬学系研究科, 特任研究員
Review Section/Research Field	Principal Investigator Biological pharmacy
Keywords	Principal Investigator Nurr1 / p38 / ASK1 / 核内受容体 / 細胞死 / 酸化ストレス / ストレスシグナル / パーキンソン病 / ドパミン神経細胞 / シグナル伝達 / ストレス

ストレスシグナルによるアポトーシスと炎症の選択的制御機構Principal Investigator
- Principal Investigator
  
  関根悠介
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
Regulation of nuclear receptor Nurr1 by stress-responsive signalingPrincipal Investigator
- Principal Investigator
  
  SEKINE Yusuke
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo

All 2013 2012 2011 2010

All Journal Article Presentation

[Journal Article] The kelch repeat protein KLHDC10 regulates oxidative stress-induced ASK1 activation by suppressing PP52012
- Author(s)
  Yusuke Sekine, Ryo Hatanaka, Takeshi Watanabe. Naoki Sono, Shun-ichiro Iemura, Tohru Natsume, Erina Kuranaga, Masayuki Miura, Kohsuke Takeda, and Hidenori Ichijo
- Journal Title
  
  Molecular Cell
  
  Volume: 48 Issue: 5 Pages: 1-13
- DOI
  10.1016/j.molcel.2012.09.018
- NAID
  120007150217
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J09553, KAKENHI-PROJECT-20229004, KAKENHI-PLANNED-21117006, KAKENHI-PROJECT-22390347, KAKENHI-PROJECT-23229002, KAKENHI-PROJECT-23659033, KAKENHI-PROJECT-24659027, KAKENHI-PROJECT-24790070, KAKENHI-PUBLICLY-23117510, KAKENHI-ORGANIZER-24115001, KAKENHI-PLANNED-24115007
[Journal Article] Prevention of apoptosis by mitochondrial phosphatase PGAM5 in the mushroom body is crucial for heat shock resistance in Drosophila melanogaster2012
- Author(s)
  Ishida, Y., et al.
- Journal Title
  
  PloS ONE
  
  Volume: 7 Issue: 2 Pages: 3006-3016
- DOI
  10.1371/journal.pone.0030265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229004, KAKENHI-PROJECT-22390347, KAKENHI-PROJECT-22890031, KAKENHI-PUBLICLY-23117510, KAKENHI-PROJECT-23229002, KAKENHI-PROJECT-23659033
[Journal Article] ストレスシグナルによるアポトーシス制御と癌形成における役割2011
- Author(s)
  関根悠介、武田弘資、一條秀憲
- Journal Title
  
  実験医学増刊
  
  Volume: 29 Pages: 222-228
- Data Source
  KAKENHI-PROJECT-22890031
[Journal Article] p38 MAP kinase regulates the expression of genes in the dopamine synthesis pathway through phosphorylation of NR4A nuclear receptors2011
- Author(s)
  Sekine,Y., Takagahara,S., Hatanaka, R., Watanabe, T., Oguchi, H., Noguchi, T., Naguro, I., Kobayashi, K., Tsunoda, M., Funatsu, T., Nomura, H., Toyoda, T., Matsuki, N., Kuranaga, E., Miura, M., Takeda, K., and Ichijo, H.
- Journal Title
  
  J. Cell Sci.
  
  Volume: 124 Issue: 17 Pages: 3006-3016
- DOI
  10.1242/jcs.085902
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229004, KAKENHI-PROJECT-22390347, KAKENHI-PROJECT-22890031, KAKENHI-PUBLICLY-23117510, KAKENHI-PROJECT-23659033, KAKENHI-PROJECT-23700367, KAKENHI-PROJECT-23790078
[Journal Article] ストレスシグナルによるアポトーシス制御と癌形成における役割2011
- Author(s)
  関根悠介, 武田弘資, 一條秀憲
- Journal Title
  
  実験医学増刊,羊土社
  
  Volume: 29 Pages: 222-228
- Data Source
  KAKENHI-PROJECT-22890031
[Journal Article] 哺乳類細胞のストレス受容・伝達機構とそれに起因する疾患2010
- Author(s)
  畑中良、関根悠介、一條秀憲
- Journal Title
  
  化学と生物
  
  Volume: 48 Pages: 471-477
- NAID
  10026875538
- Data Source
  KAKENHI-PROJECT-22890031
[Journal Article] 哺乳類細胞のストレス受容・伝達機構とそれに起因する疾患2010
- Author(s)
  畑中良, 関根悠介, 一條秀憲
- Journal Title
  
  化学と生物,学会出版センター
  
  Volume: 48 Pages: 471-477
- NAID
  10026875538
- Data Source
  KAKENHI-PROJECT-22890031
[Presentation] The kelch repeat protein KLHDC10 regulates oxidative stress-induced ASK1 activation by suppressing PP52013
- Author(s)
  Sekine, Y., Takeda, K., Ichijo, H.
- Organizer
  10^<th> international Conference on Protein Phosphatase
- Place of Presentation
  がん研究所、東京都
- Year and Date
  2013-02-09
- Data Source
  KAKENHI-PROJECT-24790070
[Presentation] Regulatory mechanism of the ASK1-MAPK signaling in oxidative stress-induced cell death2012
- Author(s)
  Sekine Y., Ichijo, H.
- Organizer
  International Symposium 2012 on Signaling Functions of Reactive Oxygen Species
- Place of Presentation
  九州大学(招待講演)
- Year and Date
  2012-12-17
- Data Source
  KAKENHI-PROJECT-24790070
[Presentation] ストレス応答キナーゼによる酸化ストレス応答と細胞死2011
- Author(s)
  関根悠介,一條秀憲
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都国際会館
- Data Source
  KAKENHI-PROJECT-22890031
[Presentation] Roles of the kelch repeat protein KLHDC10 in oxidative stress-induced ASK1 activation2011
- Author(s)
  Sekine Y., Hatanaka, R., Watanabe, T., Mosallanejad, K., Takeda, K. and Ichijo, H
- Organizer
  13th International TNF Conference
- Place of Presentation
  Awaji Yumebutai International Conference Center
- Data Source
  KAKENHI-PROJECT-22890031
[Presentation] Roles of the Kelch repeat protein KLHDC10 in oxidative stress-induced ASK1 activation2011
- Author(s)
  Sekine, Y., et al.
- Organizer
  13th International TNF Conference (TNF2011)
- Place of Presentation
  淡路島夢舞台国際会議場
- Data Source
  KAKENHI-PROJECT-22890031
[Presentation] Roles of the Kelch repeat protein KLHDC10 in oxidative stress-induced ASK1 activation2011
- Author(s)
  Sekine, Y., et al.
- Organizer
  1st Asia-Pacific Drosophila Research Conference
- Place of Presentation
  Taipei, Taiwan
- Data Source
  KAKENHI-PROJECT-22890031
[Presentation] Roles of the kelch repeat protein KLHDC10 in oxidative stress-induced ASK1 activation2011
- Author(s)
  Sekine Y., Hatanaka, R., Watanabe, T., Takeda, K. and Ichijo, H
- Organizer
  1^<st> Asia-Pacific Drosophila Research Conference
- Place of Presentation
  Taipei, Taiwan
- Data Source
  KAKENHI-PROJECT-22890031
[Presentation] 酸化ストレス依存的なASK1活性制御機構におけるKLHDC10の役割2010
- Author(s)
  関根悠介,武田弘資,一條秀憲
- Organizer
  BMB2010(第83回日本生化学会大会・第33回日本分子生物学会年会合同大会)
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-22890031
[Presentation] 酸化ストレス依存的なASK1活性制御機構におけるKLHDC10の役割2010
- Author(s)
  関根悠介
- Organizer
  BMB2010
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22890031

1. 武田弘資

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 名黒功

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 野口拓也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 一條秀憲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 渡邊毅

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SEKINE Yusuke 関根 悠介

Research Projects

Research Products

Co-Researchers

ストレスシグナルによるアポトーシスと炎症の選択的制御機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of nuclear receptor Nurr1 by stress-responsive signalingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The kelch repeat protein KLHDC10 regulates oxidative stress-induced ASK1 activation by suppressing PP52012

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Prevention of apoptosis by mitochondrial phosphatase PGAM5 in the mushroom body is crucial for heat shock resistance in Drosophila melanogaster2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ストレスシグナルによるアポトーシス制御と癌形成における役割2011

Author(s)

Journal Title

Data Source

[Journal Article] p38 MAP kinase regulates the expression of genes in the dopamine synthesis pathway through phosphorylation of NR4A nuclear receptors2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ストレスシグナルによるアポトーシス制御と癌形成における役割2011

Author(s)

Journal Title

Data Source

[Journal Article] 哺乳類細胞のストレス受容・伝達機構とそれに起因する疾患2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] 哺乳類細胞のストレス受容・伝達機構とそれに起因する疾患2010

Author(s)

Journal Title

NAID

Data Source

[Presentation] The kelch repeat protein KLHDC10 regulates oxidative stress-induced ASK1 activation by suppressing PP52013

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Regulatory mechanism of the ASK1-MAPK signaling in oxidative stress-induced cell death2012

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ストレス応答キナーゼによる酸化ストレス応答と細胞死2011

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Roles of the kelch repeat protein KLHDC10 in oxidative stress-induced ASK1 activation2011

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Roles of the Kelch repeat protein KLHDC10 in oxidative stress-induced ASK1 activation2011

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Roles of the Kelch repeat protein KLHDC10 in oxidative stress-induced ASK1 activation2011

Author(s)

Organizer

SEKINE Yusuke 関根悠介