Nishio Nobuhiro 西尾信博

… Alternative Names

NIshio Nobuhiro 西尾信博

西尾信博ニシオノブヒロ

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Researcher Number	00586430
Other IDs	https://orcid.org/0000-0002-0267-3853
Affiliation (Current)	2025: 名古屋大学, 医学部附属病院, 特任准教授 2025: 名古屋大学, 医学系研究科, 特任准教授
Affiliation (based on the past Project Information) *help	2023: 名古屋大学, 医学系研究科, 特任准教授 2019 – 2022: 名古屋大学, 医学部附属病院, 特任講師 2015 – 2017: 名古屋大学, 医学部附属病院, 特任助教 2011: 愛知県がんセンター(研究所), 腫瘍免疫学部, 主任研究員
Review Section/Research Field	Principal Investigator Pediatrics / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator piggyBac / CAR / GD2 / キメラ抗原受容体 / 神経芽腫 / キメラ高原受容体 / 骨肉腫 / ゾレドロネート / 癌幹細胞 / γδT細胞 … More Except Principal Investigator … More 化学療法 / 代謝拮抗剤 / MYCN / 合成致死 / 神経芽腫 Less

CAR-T細胞機能を向上させるCAR構造の最適化Principal Investigator
- Principal Investigator
  
  西尾信博
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Nagoya University
Utilization of antimetabolite drugs for the treatment of high-risk neuroblastoma
- Principal Investigator
  
  Kiyonari Shinichi
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kitasato University
  Nagoya University
Development of a novel chimeric antigen receptor gene-modified T cell therapy targeting GD2 for neuroblastomaPrincipal Investigator
- Principal Investigator
  
  Nishio Nobuhiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Nagoya University
Novel chimeric antigen receptor modified T cells against IGF receptor for osteosarcomaPrincipal Investigator
- Principal Investigator
  
  NIshio Nobuhiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Nagoya University
γδT細胞を使用した、神経芽腫幹細胞に対する免疫療法の基盤研究Principal Investigator
- Principal Investigator
  
  西尾信博
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Aichi Cancer Center Research Institute

All 2021 2020 2019 2018 2017 2016 2011

All Journal Article Presentation Patent

[Journal Article] CAR－T 細胞療法に対する治療抵抗性メカニズム2021
- Author(s)
  西尾信博、高橋義行
- Journal Title
  
  医学のあゆみ
  
  Volume: 277 Pages: 867-871
- Data Source
  KAKENHI-PROJECT-19K08273
[Journal Article] 【急性リンパ芽球性白血病】急性リンパ芽球性白血病に対するCAR-T細胞療法2021
- Author(s)
  西尾信博
- Journal Title
  
  血液内科
  
  Volume: 82 Pages: 486-492
- Data Source
  KAKENHI-PROJECT-19K08273
[Journal Article] Enhanced Expression of Anti-CD19 Chimeric Antigen Receptor in piggyBac Transposon-Engineered T Cells2018
- Author(s)
  Morita Daisuke、Nishio Nobuhiro、Saito Shoji、Tanaka Miyuki、Kawashima Nozomu、Okuno Yusuke、Suzuki Satoshi、Matsuda Kazuyuki、Maeda Yasuhiro、Wilson Matthew H.、Dotti Gianpietro、Rooney Cliona M.、Takahashi Yoshiyuki、Nakazawa Yozo
- Journal Title
  
  Molecular Therapy - Methods & Clinical Development
  
  Volume: 8 Pages: 131-140
- DOI
  10.1016/j.omtm.2017.12.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19311, KAKENHI-PROJECT-15K09648
[Patent] キメラ抗原受容体を発現する遺伝子改変Ｔ細胞の調製方法2021
- Inventor(s)
  西尾信博、高橋義行
- Industrial Property Rights Holder
  名古屋大学
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-19K08273
[Patent] キメラ抗原受容体遺伝子改変リンパ球の調製方法2019
- Inventor(s)
  西尾信博、高橋義行
- Industrial Property Rights Holder
  名古屋大学
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-19K08273
[Patent] キメラ抗原受容体を発現する遺伝子改変Ｔ細胞の調製方法2016
- Inventor(s)
  西尾信博、中沢洋三、田中美幸、盛田大介、高橋義行
- Industrial Property Rights Holder
  名古屋大学
- Industrial Property Rights Type
  特許
- Filing Date
  2016-10-07
- Overseas
- Data Source
  KAKENHI-PROJECT-15K09648
[Presentation] A phase I study of CD19 chimeric antigen receptor-T cells generated by the piggyBac transposon vector for acute lymphoblastic leukemia2021
- Author(s)
  Nobuhiro Nishio, Ryo Hanajiri, Yuichi Ishikawa, Makoto Murata, Rieko Taniguchi, Motoharu Hamada, Eri Nishikawa, Nozomu Kawashima, Atsushi Narita, Hideki Muramatsu, Yoshiyuki Takahashi
- Organizer
  第63回米国血液学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08273
[Presentation] CD19.CAR-T療法後の治療決定におけるNGS based MRDの有用性の検討2021
- Author(s)
  西尾信博、濱田太立、奥野友介、津村悠介、前村遼、今屋雅之、山森彩子、谷口理恵子、川島希、西川英里、成田敦、村松秀城、Kai Wang、Huyong Zheng、Lung-Ji Chang、小島勢二、高橋義行
- Organizer
  第13回血液疾患免疫療法学会
- Data Source
  KAKENHI-PROJECT-19K08273
[Presentation] CD19-CAR-T細胞療法後に再発したB-ALLに対するCD19-CAR-T細胞の再投与2021
- Author(s)
  西尾信博、濱田太立、川島希、西川英里、成田敦、村松秀城、Kai Wang、Huyong Zheng、Lung-Ji Chang、高橋義行
- Organizer
  第63回日本小児血液がん学会
- Data Source
  KAKENHI-PROJECT-19K08273
[Presentation] 急性リンパ性白血病に対するpiggyBacトランスポゾン法によるCD19CAR-T療法の臨床第I相試験2021
- Author(s)
  西尾信博、葉名尻良、石川裕一、西田徹也、村田誠、濱田太立、西川英里、川島希、奥野友介、成田敦、村松秀城、高橋義行
- Organizer
  第83回日本血液学会
- Data Source
  KAKENHI-PROJECT-19K08273
[Presentation] タイにおけるPiggyBacトランスポゾン法によるCD19キメラ抗原受容体遺伝子改変T細胞療法臨床第Ｉ相試験への技術支援2020
- Author(s)
  西尾信博, Nattiya Hirankarn, Udomsak Bunworasate, Koramit Suppipat, Supannikar Tawinwang, Rattapoom Thaiwong, Suparat Tudsamran, 中沢洋三, 濱田太立, 市川大輔, 西川英里, 川島希, 成田敦, 村松秀城, 小島勢二, 高橋義行
- Organizer
  第12回血液疾患免疫療法学会
- Data Source
  KAKENHI-PROJECT-19K08273
[Presentation] 非ウイルスベクター法によるＣＡＲ－Ｔ細胞療法臨床試験2020
- Author(s)
  西尾信博
- Organizer
  第123回日本小児科学会
- Data Source
  KAKENHI-PROJECT-19K08273
[Presentation] Evaluation of next-generation sequencing-based minimal residual disease analysis after CAR-T therapy2020
- Author(s)
  Nobuhiro Nishio, Motoharu Hamada, Yusuke Okuno, Masayuki Imaya, Taro Yoshida, Ayako Yamamori, Shunsuke Miwata, Kotaro Narita, Hironobu Kitazawa, Daisuke Ichikawa, Nozomu Kawashima, Eri Nishikawa, Atsushi Narita, Hideki Muramatsu, Kai Wang, Huyong Zheng, Lung-Ji Chang, Seiji Kojima, Yoshiyuki Takahashi
- Organizer
  第82回日本血液学会
- Data Source
  KAKENHI-PROJECT-19K08273
[Presentation] Durable Remission After Salvage Chemotherapy with Combining Bortezomib and Vorinostat Followed by CD19 CAR-T Therapy in a Patient with MLL-rearranged ALL After Early Relapse Post Allogeneic Hematopoietic Stem Cell Transplantation2017
- Author(s)
  Nobuhiro Nishio, Kai Wang, Shinsuke Kataoka, Kotaro Narita, Hironobu Kitazawa, et al.
- Organizer
  第５９回米国血液学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09648
[Presentation] PiggyBac Mediated T cells Expressing Anti-CD19 Chimeric Antigen Receptor for a Clinical Trial2017
- Author(s)
  Nobuhiro Nishio, Yozo Nakazawa, Motoharu Hamada, Satoshi Suzuki, Miyuki Takana, Daisuke Morita, Nozomu Kawashima, Yusuke Okuno, Atsushi Narita, Asahito Hama, Hideki Muramatsu, Seiji Kojima, Yoshiyuki Takahashi
- Organizer
  第8回日本血液学会国際シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09648
[Presentation] PiggyBac Mediated T cells Expressing anti CD19 Chimeric Antigen Receptor for a Clinical Trial2017
- Author(s)
  Nobuhiro Nishio, Yozo Nakazawa, Motoharu Hamada, Satoshi Suzuki, Miyuki Takana, Daisuke Morita, Nozomu Kawashima, Yusuke Okuno, Atsushi Narita, Asahito Hama, Hideki Muramatsu, Wilson H. Matthew, Cliona M. Rooney, Gianpietro Dotti, Seiji Kojima, Yoshiyuki Takahashi
- Organizer
  第20回American Society of Gene and Cell Therapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09648
[Presentation] PiggyBac遺伝子改変CD19キメラ抗原受容体T細胞療法のFirst in Human試験にむけた基盤研究2017
- Author(s)
  西尾信博、鈴木哲、奥野友介、中沢洋三、田中美幸、盛田大介、濱田太立、川島希、成田敦、村松秀城、濱麻人、小島勢二、高橋義行
- Organizer
  第６回日本血液学会東海地方会
- Data Source
  KAKENHI-PROJECT-15K09648
[Presentation] CAR-T cell in Leukemia2017
- Author(s)
  Nobuhiro Nishio
- Organizer
  Precision Oncology: Genomics Data from Thai patients vs. Global Counterparts
- Place of Presentation
  バンコク、タイ
- Year and Date
  2017-03-02
- Invited
- Data Source
  KAKENHI-PROJECT-15K09648
[Presentation] Detection of integration sites of CD19 chimeric antigen receptor gene in a non-viral gene transfer system.2016
- Author(s)
  Motoharu Hamada, Yusuke Okuno, Nobuhiro Nishio, Matthew H. Wilson, Seiji Kojima, Yozo Nakazawa, and Yoshiyuki Takahashi
- Organizer
  American Society of Gene and Cell Therapy
- Place of Presentation
  Washington, DC, USA
- Year and Date
  2016-05-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09648
[Presentation] PiggyBac mediated CD19 chimeric antigen receptor modified T cells for a first in human clinical trial.2016
- Author(s)
  Nobuhiro Nishio, Yozo Nakazawa, Motoharu Hamada, Satoshi Suzuki, Miyuki Takana, Daisuke Morita, Nozomu Kawashima, Yusuke Okuno, Atsushi Narita, Asahito Hama, Hideki Muramatsu, Wilson H. Matthew, Cliona M. Rooney, Gianpietro Dotti, Seiji Kojima, Yoshiyuki Takahashi.
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K09648
[Presentation] PiggyBac mediated T cells expressing CD19 chimeric antigen receptor for a “first in human” clinical trial2016
- Author(s)
  Nobuhiro Nishio, Yozo Nakazawa, Motoharu Hamada, Satoshi Suzuki, Miyuki Takana, Daisuke Morita, Nozomu Kawashima, Yusuke Okuno, Atsushi Narita, Asahito Hama, Hideki Muramatsu, Wilson H. Matthew, Cliona M. Rooney, Gianpietro Dotti, Seiji Kojima, Yoshiyuki Takahashi
- Organizer
  第58回日本小児血液・がん学会学術集会
- Place of Presentation
  品川プリンスホテル（東京都品川区）
- Year and Date
  2016-12-15
- Data Source
  KAKENHI-PROJECT-15K09648
[Presentation] Detection of Integration Sites of CD19 Chimeric Antigen Receptor Gene in a Non-viral Gene Transfer System.2016
- Author(s)
  Motoharu Hamada, Yusuke Okuno, Nobuhiro Nishio, Matthew H. Wilson, Nozomu Kawashima, Atsushi Narita, Hideki Muramatsu, Asahito Hama, Seiji Kojima, Yozo Nakazawa, Yoshiyuki Takahashi.
- Organizer
  The 7th JSH 国際シンポジウム
- Place of Presentation
  淡路夢舞台国際会議場（兵庫県淡路市）
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-15K09648
[Presentation] Genome-wide Profile of Integration Sites of Chimeric Antigen Receptor (CAR) Gene in PiggyBac-modified Human T Cells.2016
- Author(s)
  Motoharu Hamada, Yusuke Okuno, Nobuhiro Nishio, Nozomu Kawashima, Atsushi Narita, Hideki Muramatsu, Asahito Hama, Seiji Kojima, Yozo Nakazawa, and Yoshiyuki Takahashi
- Organizer
  第58回日本小児血液・がん学会学術集会
- Place of Presentation
  品川プリンスホテル（東京都品川区）
- Year and Date
  2016-12-15
- Data Source
  KAKENHI-PROJECT-15K09648
[Presentation] γδT細胞を使用した神経芽腫に対する免疫療法に向けた検討2011
- Author(s)
  西尾信博
- Organizer
  第114回日本小児科学会学術集会
- Place of Presentation
  グランドプリンスホテル高輪(東京都)
- Data Source
  KAKENHI-PROJECT-23791214

1. 高橋義行 (40432273)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. Kiyonari Shinichi (70570836)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 中沢洋三 (60397312)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
4. OKUNO Yusuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. ITO Masafumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 川島希

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nishio Nobuhiro 西尾 信博

NIshio Nobuhiro 西尾 信博

西尾 信博 ニシオ ノブヒロ

Research Projects

Research Products

Co-Researchers

CAR-T細胞機能を向上させるCAR構造の最適化Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Utilization of antimetabolite drugs for the treatment of high-risk neuroblastoma

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a novel chimeric antigen receptor gene-modified T cell therapy targeting GD2 for neuroblastomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel chimeric antigen receptor modified T cells against IGF receptor for osteosarcomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

γδT細胞を使用した、神経芽腫幹細胞に対する免疫療法の基盤研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] CAR－T 細胞療法に対する治療抵抗性メカニズム2021

Author(s)

Journal Title

Data Source

[Journal Article] 【急性リンパ芽球性白血病】急性リンパ芽球性白血病に対するCAR-T細胞療法2021

Author(s)

Journal Title

Data Source

[Journal Article] Enhanced Expression of Anti-CD19 Chimeric Antigen Receptor in piggyBac Transposon-Engineered T Cells2018

Author(s)

Journal Title

DOI

Data Source

[Patent] キメラ抗原受容体を発現する遺伝子改変Ｔ細胞の調製方法2021

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Patent] キメラ抗原受容体遺伝子改変リンパ球の調製方法2019

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Patent] キメラ抗原受容体を発現する遺伝子改変Ｔ細胞の調製方法2016

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Presentation] A phase I study of CD19 chimeric antigen receptor-T cells generated by the piggyBac transposon vector for acute lymphoblastic leukemia2021

Author(s)

Organizer

Data Source

[Presentation] CD19.CAR-T療法後の治療決定におけるNGS based MRDの有用性の検討2021

Author(s)

Organizer

Data Source

[Presentation] CD19-CAR-T細胞療法後に再発したB-ALLに対するCD19-CAR-T細胞の再投与2021

Author(s)

Organizer

Data Source

[Presentation] 急性リンパ性白血病に対するpiggyBacトランスポゾン法によるCD19CAR-T療法の臨床第I相試験2021

Nishio Nobuhiro 西尾信博

NIshio Nobuhiro 西尾信博

西尾信博ニシオノブヒロ