Rai Shoho 雷小峰

… Alternative Names

LEI Xiao-Feng 雷小峰

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Researcher Number	00595069
Other IDs
Affiliation (Current)	2025: 昭和大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2021 – 2024: 昭和大学, 医学部, 助教 2019 – 2020: 昭和大学, 医学部, 普通研究生 2018: 昭和大学, 医学部, その他 2017: 昭和大学, 医学部, 普通研究生 2012 – 2016: 昭和大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 53050:Dermatology-related / Basic Section 53030:Respiratory medicine-related / Digestive surgery / Cardiovascular medicine / General surgery Except Principal Investigator Basic Section 49010:Pathological biochemistry-related
Keywords	Principal Investigator Hic-5 / 大動脈瘤 / 全身性強皮症 / 強皮症 / 肺線維化 / 接着斑分子 / TGF-β / 細胞外マトリックス / 肺線維症 / 膵疾患 … More / 膵星細胞 / 膵癌 / 慢性膵炎 / 膵炎 / 膵臓星細胞 / 膵臓線維化 / マルファン症候群 / 細胞接着斑 / 活性酸素種 / 平滑筋細胞 / 腹部大動脈瘤 … More Except Principal Investigator 線維化 / MASH Less

老化関連遺伝子を標的としたアンチセンス核酸によるMASH病態改善機構の解明
- Principal Investigator
  
  金山朱里
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Showa University
Analysis of novel target molecules for systemic scleroderma using single cell analysis.Principal Investigator
- Principal Investigator
  
  雷小峰
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Showa University
Novel pulmonary fibrosis therapeutic strategy targeting TGF-beta inducible genePrincipal Investigator
- Principal Investigator
  
  Lei Xiao-Feng
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Showa University
Establishment of novel target molecules for pancreatic diseases by regulating stellate cell activationPrincipal Investigator
- Principal Investigator
  
  LEI XIAOFENG
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Showa University
Roles of hydrogen peroxide-induced clone 5 in pathogenesis of thoracic aortic aneurysm in marfan syndromPrincipal Investigator
- Principal Investigator
  
  Lei Xiao Feng
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Showa University
Identification of Hic-5 as a novel molecule in the development of abdominal aortic aneurysmsPrincipal Investigator
- Principal Investigator
  
  LEI Xiao-Feng
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General surgery
- Research Institution
  Showa University

All 2023 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] Innate Immune System Regulated by Stimulator of Interferon Genes, a Cytosolic DNA Sensor, Regulates Endothelial Function2023
- Author(s)
  Pham Phuong Tran、Bavuu Oyunbileg、Kim‐Kaneyama Joo‐Ri、Lei Xiao‐Feng、Yamamoto Takayuki、Otsuka Kenichiro、Suto Kumiko、Kusunose Kenya、Yagi Shusuke、Yamada Hirotsugu、Soeki Takeshi、Shimabukuro Michio、Barber Glen N.、Sata Masataka、Fukuda Daiju
- Journal Title
  
  Journal of the American Heart Association
  
  Volume: 12 Issue: 22
- DOI
  10.1161/jaha.123.030084
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08109, KAKENHI-PROJECT-23K07792, KAKENHI-PROJECT-23K24330
[Journal Article] Knockdown of mechanosensitive adaptor Hic-5 ameliorates post-traumatic osteoarthritis in rats through repression of MMP-132023
- Author(s)
  Miyauchi Aya、Noguchi Masahito、Lei Xiao-Feng、Sakaki Masashi、Kobayashi-Tanabe Momoko、Haraguchi Shogo、Miyazaki Akira、Kim-Kaneyama Joo-ri
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 7446-7446
- DOI
  10.1038/s41598-023-34659-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07792, KAKENHI-PROJECT-21K16098
[Journal Article] Hic-5 is required for activation of pancreatic stellate cells and development of pancreatic fibrosis in chronic pancreatitis2020
- Author(s)
  Gao Lin、Lei Xiao-Feng、Miyauchi Aya、Noguchi Masahito、Omoto Tomokatsu、Haraguchi Shogo、Miyazaki Takuro、Miyazaki Akira、Kim-Kaneyama Joo-ri
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 19105-19105
- DOI
  10.1038/s41598-020-76095-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08404, KAKENHI-PROJECT-19K08590, KAKENHI-PROJECT-19K09033, KAKENHI-PROJECT-19K09159, KAKENHI-PROJECT-20K08525, KAKENHI-PROJECT-19H03110
[Journal Article] Alleviation of murine osteoarthritis by deletion of the focal adhesion mechanosensitive adapter, Hic-52019
- Author(s)
  Miyauchi Aya、Kim-Kaneyama Joo-ri、Lei Xiao-Feng、Chang Song Ho、Saito Taku、Haraguchi Shogo、Miyazaki Takuro、Miyazaki Akira
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 15770-15770
- DOI
  10.1038/s41598-019-52301-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08404, KAKENHI-PROJECT-19K08590, KAKENHI-PROJECT-19K09033, KAKENHI-PROJECT-19H03110, KAKENHI-PROJECT-17K09869, KAKENHI-PROJECT-17K10713, KAKENHI-PROJECT-17K10955, KAKENHI-PROJECT-17K10997
[Journal Article] Toll‐Like Receptor 9 Plays a Pivotal Role in Angiotensin II Induced Atherosclerosis2019
- Author(s)
  Fukuda Daiju、Nishimoto Sachiko、Aini Kunduziayi、Tanaka Atsushi、Nishiguchi Tsuyoshi　et al.
- Journal Title
  
  Journal of the American Heart Association
  
  Volume: 8 Issue: 7
- DOI
  10.1161/jaha.118.010860
- NAID
  120006602927
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09479, KAKENHI-PROJECT-17K10713, KAKENHI-PROJECT-16H05299, KAKENHI-PROJECT-19K21501, KAKENHI-PROJECT-16K09517, KAKENHI-PROJECT-16K10553, KAKENHI-PROJECT-18K07910, KAKENHI-PROJECT-19K08404, KAKENHI-PROJECT-19K08584, KAKENHI-PROJECT-18H02894, KAKENHI-PROJECT-19H03654
[Journal Article] Light-at-night exposure affects brain development through pineal allopregnanolone-dependent mechanisms2019
- Author(s)
  Haraguchi S, Kamata M, Tokita T, Tashiro KI, Sato M, Nozaki M, Okamoto-Katsuyama M, Shimizu I, Han G, Chowdhury VS, Lei XF, Miyazaki T, Kim-Kaneyama JR, Nakamachi T, Matsuda K, Ohtaki H, Tokumoto T, Tachibana T, Miyazaki A, Tsutsui K.
- Journal Title
  
  eLife
  
  Volume: 8
- DOI
  10.7554/elife.45306
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06310, KAKENHI-PROJECT-19K08404, KAKENHI-PROJECT-19K08590, KAKENHI-PROJECT-19K09033, KAKENHI-PROJECT-16H04812, KAKENHI-PROJECT-18H02473, KAKENHI-PROJECT-19H03110, KAKENHI-PROJECT-17K09869, KAKENHI-PROJECT-17K10713, KAKENHI-PROJECT-16K13054, KAKENHI-PROJECT-16H05443
[Journal Article] Expression of steroidogenic enzymes and metabolism of steroids in COS-7 cells known as non-steroidogenic cells.2018
- Author(s)
  Nozaki M, Haraguchi S, Miyazaki T, Shigeta D, Kano N, Lei XF, Kim-Kaneyama JR, Minakata H, Miyazaki A, Tsutsui K.
- Journal Title
  
  Sci Rep.
  
  Volume: 8 Issue: 1 Pages: 2167-2167
- DOI
  10.1038/s41598-018-20226-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09418, KAKENHI-PROJECT-17K09869, KAKENHI-PROJECT-17K10713, KAKENHI-PROJECT-16K10553
[Journal Article] The impact of stromal Hic-5 on the tumorigenesis of colorectal cancer through lysyl oxidase induction and stromal remodeling.2018
- Author(s)
  Omoto T, Kim-Kaneyama JR, Lei XF, Orimo A, Ohnishi K, Yoshihara K, Miyauchi A, Li S, Gao L, Umemoto T, Tanaka J, Nakahara K, Takeya M, Ishida F, Kudo SE, Haraguchi S, Miyazaki T, Miyazaki A.
- Journal Title
  
  Oncogene.
  
  Volume: 37 Issue: 9 Pages: 1205-1219
- DOI
  10.1038/s41388-017-0033-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09418, KAKENHI-PROJECT-16K10553, KAKENHI-PROJECT-17K09869, KAKENHI-PROJECT-17K10713, KAKENHI-PROJECT-16K15598, KAKENHI-PROJECT-16K15625, KAKENHI-PROJECT-15K14385, KAKENHI-PROJECT-15K15611, KAKENHI-PROJECT-17H04060, KAKENHI-PROJECT-16H06267
[Journal Article] Functional Heterogeneity of Nadph Oxidases in Atherosclerotic and Aneurysmal Diseases2017
- Author(s)
  Kigawa Y, Miyazaki T, Lei XF, Kim-Kaneyama JR, Miyazaki A.
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 24 Issue: 1 Pages: 1-13
- DOI
  10.5551/jat.33431
- NAID
  130005188266
- ISSN
  1340-3478, 1880-3873
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461149, KAKENHI-PROJECT-26461368, KAKENHI-PROJECT-26860588, KAKENHI-PROJECT-15K09418, KAKENHI-PROJECT-16K10553
[Journal Article] Calpain-6 confers atherogenicity to macrophages by dysregulating pre-mRNA splicing.2016
- Author(s)
  Miyazaki T, Tonami K, Hata S, Aiuchi T, Ohnishi K, Lei XF, Kim-Kaneyama JR, Takeya M, Itabe H, Sorimachi H, Kurihara H, Miyazaki A
- Journal Title
  
  J Clin Invest
  
  Volume: 126 Issue: 9 Pages: 3417-3432
- DOI
  10.1172/jci85880
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02389, KAKENHI-PROJECT-26460454, KAKENHI-PROJECT-26461149, KAKENHI-PROJECT-26461368, KAKENHI-PROJECT-15K21367, KAKENHI-PROJECT-26860588, KAKENHI-PROJECT-15K07944, KAKENHI-PROJECT-15K09418, KAKENHI-PROJECT-16K10553, KAKENHI-PROJECT-26450172, KAKENHI-PROJECT-15H02536
[Journal Article] Hic-5 deficiency attenuates the activation of hepatic stellate cells and liver fibrosis through upregulation of Smad7 in mice2016
- Author(s)
  Xiao-Feng Lei, Wenguang Fu, Joo-ri Kim-Kaneyama, Tomokatsu Omoto, Takuro Miyazaki, Bo Li, Akira Miyazaki
- Journal Title
  
  Journal of Hepatology
  
  Volume: 64 Issue: 1 Pages: 110-117
- DOI
  10.1016/j.jhep.2015.08.026
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09418, KAKENHI-PROJECT-26461149, KAKENHI-PROJECT-26461368, KAKENHI-PROJECT-26860588
[Journal Article] The pathophysiological role of oxidized cholesterols in epicardial fat accumulation and cardiac dysfunction: a study in swine fed a high caloric diet with an inhibitor of intestinal cholesterol absorption, ezetimibe.2016
- Author(s)
  Shimabukuro M, Okawa C, Yamada H, Yanagi S, Uematsu E, Sugasawa N, Kurobe H, Hirata Y, Kim-Kaneyama JR, Lei XF, Takao S, Tanaka Y, Fukuda D, Yagi S, Soeki T, Kitagawa T, Masuzaki H, Sato M, Sata M.
- Journal Title
  
  J Nutr Biochem.
  
  Volume: 35 Pages: 66-73
- DOI
  10.1016/j.jnutbio.2016.05.010
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461149, KAKENHI-PROJECT-26860588, KAKENHI-PROJECT-16K01823, KAKENHI-PROJECT-16K09517, KAKENHI-PROJECT-16K10553, KAKENHI-PROJECT-16K15632
[Journal Article] Calpastatin counteracts pathological angiogenesis by inhibiting suppressor of cytokine signaling 3 degradation in vascular endothelial cells.2015
- Author(s)
  Miyazaki, T., Taketomi, Y., Saito, Y., Hosono, T., Lei, X.F., Kim-Kaneyama, J.R., Arata, S., Takahashi, H., Murakami, M., and Miyazaki, A.
- Journal Title
  
  Circ. Res.
  
  Volume: 116 Issue: 7 Pages: 1170-1181
- DOI
  10.1161/circresaha.116.305363
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390021, KAKENHI-PROJECT-24790784, KAKENHI-PROJECT-25460087, KAKENHI-PROJECT-26461149, KAKENHI-PROJECT-26461368, KAKENHI-PROJECT-26860588, KAKENHI-PROJECT-15K09418, KAKENHI-PLANNED-15H05905
[Journal Article] Role of HIC-5 in the formation of microvilli-like structures and the monocyte-endotherial interaction that accelerates atherosclerosis2015
- Author(s)
  Shigeko Arita-Okubo, et al
- Journal Title
  
  Cardiovasc Res
  
  Volume: 105 Issue: 3 Pages: 361-371
- DOI
  10.1093/cvr/cvv003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591241, KAKENHI-PROJECT-24790784, KAKENHI-PROJECT-25293089, KAKENHI-PROJECT-26460454, KAKENHI-PROJECT-26461149, KAKENHI-PROJECT-26461368, KAKENHI-PROJECT-26860588, KAKENHI-PROJECT-15K07944, KAKENHI-PROJECT-15K09418
[Journal Article] ACAT1-associated Late Endosomes/Lysosomes Significantly Improve Impaired Intracellular Cholesterol Metabolism and the Survival of Niemann-Pick Type C Mice2014
- Author(s)
  Kamikawa M, Lei XF, Fujiwara Y, Nishitsuji K, Mizuta H, Takeya M, Sakashita N
- Journal Title
  
  ACTA HISTOCHEMICA ET CYTOCHEMICA
  
  Volume: 47 Issue: 2 Pages: 35-43
- DOI
  10.1267/ahc.13033
- NAID
  130003390848
- ISSN
  0044-5991, 1347-5800
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23590448, KAKENHI-PROJECT-25860501, KAKENHI-PROJECT-26670190, KAKENHI-PROJECT-26860588
[Journal Article] Identification of hydrogen peroxide-inducible clone 5 as a novel scaffold for the mitogen-activated protein kinase kinase 4/p54 c-Jun N-terminal kinase pathway in the development of abdominal aortic aneurysms2014
- Author(s)
  Lei XF, Kim-Kaneyama JR, Arita-Okubo S, Offermanns S, Itabe H, Miyazaki T, Miyazaki A
- Journal Title
  
  J Am Heart Assoc
  
  Volume: 3 Issue: 3
- DOI
  10.1161/jaha.113.000747
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591341, KAKENHI-PROJECT-24791396, KAKENHI-PROJECT-26461368
[Journal Article] Role of ACAT1-positive late endosomes in macrophages: cholesterol metabolism and therapeutic applications for Niemann-Pick disease type C.2014
- Author(s)
  Sakashita N, Lei XF, Kamikawa M, Nishitsuji K.
- Journal Title
  
  J Med Invest. 2014;61(3-4):270-7.
  
  Volume: 61(3-4) Pages: 270-277
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26860588
[Journal Article] Identification of Hic-5 as a novel scaffold for the MKK4/p54 JNK pathway in the development of abdominal aortic aneurysms2014
- Author(s)
  Xiao-Feng Lei, Joo-ri Kim-Kaneyama, Shigeko Arita, Stefan Offermanns, Hiroyuki Itabe, Takuro Miyazaki, Akira Miyazaki.
- Journal Title
  
  Journal of the American Heart Association
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791396
[Journal Article] NADPH oxidase deficiency exacerbates angiotensin II-induced abdominal aortic aneurysms in mice.2014
- Author(s)
  Kigawa Y, Miyazaki T, Lei XF, Nakamachi T, Oguchi T, Kim-Kaneyama JR, Taniyama M, Tsunawaki S, Shioda S, Miyazaki A.
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: 34(11) Pages: 2413-2420
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26860588
[Journal Article] 電子顕微鏡を用いたマクロファージの機能解析 : ACAT1 陽性小胞とACAT1 陽性後期エンドゾームの発見ならびにその意義2013
- Author(s)
  坂下直実, 雷小峰, 上川将史
- Journal Title
  
  病理と臨床
  
  Volume: vol. 31 Pages: 12-12
- URL
  http://mol.medicalonline.jp/library/journal/abstract?GoodsID=ag9brysh/2013/003112/016&name=1363-1368j&UserID=202.254.227.190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791396
[Journal Article] Calpain and Atherosclerosis2013
- Author(s)
  Miyazaki T, Koya T, Kigawa Y, Oguchi T, Lei XF, Kim-Kaneyama JR, Miyazaki A
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 20 Issue: 3 Pages: 228-237
- DOI
  10.5551/jat.14787
- NAID
  130004444661
- ISSN
  1340-3478, 1880-3873
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791396
[Journal Article] 電子顕微鏡を用いたマクロファージの機能解析:ACAT1陽性小胞とACAT1陽性後期エンドゾームの発見ならびにその意義2013
- Author(s)
  坂下直実、雷小峰、上川将史
- Journal Title
  
  『病理と臨床』
  
  Volume: 31 Pages: 1363-1368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791396
[Journal Article] Hydrogen Peroxide-Inducible Clone 5 (Hic-5) as a Potential Therapeutic Target for Vascular and Other Disorders2012
- Author(s)
  Kim-Kaneyama JR, Lei XF, Arita S, Miyauchi A, Miyazaki T, Miyazaki A.
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 19 Issue: 7 Pages: 601-607
- DOI
  10.5551/jat.10736
- NAID
  130004444615
- ISSN
  1340-3478, 1880-3873
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791090, KAKENHI-PROJECT-24791396
[Journal Article] Identification of Hic-5 as a novel regulatory factor for integrinαIIbβ3 activation and platelet aggregation in mice2012
- Author(s)
  Kim-Kaneyama JR, Miyauchi A, Lei XF, Arita S, Mino T, Takeda N, Kou K, Eto K, Yoshida T, Miyazaki T, Shioda S, Miyazaki A
- Journal Title
  
  J Thromb Haemostat
  
  Volume: 10(9) Issue: 9 Pages: 1867-1874
- DOI
  10.1111/j.1538-7836.2012.04856.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591341, KAKENHI-PROJECT-24790784, KAKENHI-PROJECT-24791396, KAKENHI-PLANNED-23106004
[Presentation] 頭部に生じた硬化性萎縮性苔癬の１例2021
- Author(s)
  雷小峰，佐々木大和，岩橋ゆりこ，岩立和子，北島真理子，荒木信之、山内輝夫、小林香映，渡辺秀晃
- Organizer
  第897回東京地方会
- Data Source
  KAKENHI-PROJECT-20K08525
[Presentation] Hydrogen peroxideinducible clone 5 deficiency enhanced the pathogenesis of thoracic aortic aneurysm in Marfan syndrom３2017
- Author(s)
  雷小峰、金山朱里、宮崎拓郎、原口省吾、宮崎章
- Organizer
  第25回日本血管生物医学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10713
[Presentation] 肝線維化におけるTGF-β関連遺伝子Hic-5の機能解析2016
- Author(s)
  雷　小峰、金山　朱里、宮崎　章
- Organizer
  第52回日本肝臓学会総会
- Place of Presentation
  ホテルニューオータニ幕張, 千葉
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-26860588
[Presentation] Roles of hydrogen peroxide inducible clone 5 in Pathogenesis of Thoracic Aortic Aneurysm in Marfan Syndrom2016
- Author(s)
  Xiao-Feng Lei, Joo-ri Kim-Kaneyama, Takuro Miyazaki, Akira Miyazaki
- Organizer
  19th International Vascular Biology Meeting
- Place of Presentation
  Sheraton Boston Hotel, Massachusetts, USA.
- Year and Date
  2016-10-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860588
[Presentation] Hic-5 deficiency attenuates the activation of hepatic stellate cells and liver fibrosis through upregulation of Smad7 in mice2015
- Author(s)
  Xiao-Feng Lei, Wenguang Fu, JR Kim-Kaneyama, Akira Miyazaki.
- Organizer
  18th INTERNATIONAL SYMPOSIUM ON CELLS OF THE HEPATIC SINUSOID
- Place of Presentation
  Asilomar, California
- Year and Date
  2015-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860588
[Presentation] Calpain-6 による動脈硬化病変およびマクロファージpinocytosis の制御2013
- Author(s)
  宮崎拓郎, 礪波一夫, 秦勝志, 雷小峰, 金山朱里, 反町洋之, 栗原裕基, 宮崎章
- Organizer
  第21回日本血管生物医学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24791396
[Presentation] Deletion of hydrogen peroxide-inducible clone-5 inhibits atherosclerotic plaque formation in Apolipoprotein E knockout mice.2013
- Author(s)
  Shigeko Arita, Joo-ri Kim-Kaneyama, Xiao-Feng Lei, Takuro Miyazaki, Akira Miyazaki.
- Organizer
  第45回日本動脈硬化総会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24791396
[Presentation] Calpain-6による動脈硬化病変およびマクロファージpinocytosisの制御．2013
- Author(s)
  宮崎拓郎、礪波一夫、秦勝志、雷小峰、金山朱里、反町洋之、栗原裕基、宮崎章．
- Organizer
  第21回日本血管生物医学会学術集会．
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24791396
[Presentation] Hic-5 deficiency blocks the development of angiotensin II-induced abdominal aortic aneurysms by inhibiting c-Jun N-terminal kinase 2 in mice2013
- Author(s)
  金山朱里, 雷小峰, 有田茂子, 宮崎拓郎, 宮崎章
- Organizer
  第21回日本血管生物医学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24791396
[Presentation] Hic-5 deficiency blocks the development of angiotensin II-induced abdominal aortic aneurysms by inhibiting c-Jun N-terminal kinase 2 in mice.2013
- Author(s)
  金山朱里、雷小峰、有田茂子、宮崎拓郎、宮崎章．
- Organizer
  第21回日本血管生物医学会学術集会．
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-24791396
[Presentation] Deletion of hydrogen peroxide-inducible clone-5 inhibits atherosclerotic plaque formation in Apolipoprotein E knockout mice2013
- Author(s)
  Shigeko Arita, Joo-ri Kim-Kaneyama, Xiao-Feng Lei, Takuro Miyazaki, Akira Miyazaki
- Organizer
  第45回日本動脈硬化学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24791396
[Presentation] Hic-5 deficiency blocks the development of abdominal aortic aneurysms in mice2012
- Author(s)
  Xiao-Feng Lei, Joo-ri Kim-Kaneyama, Shigeko Arita, Takuro Miyazaki, Akira Miyazaki
- Organizer
  The17th international vascular biology meeting
- Place of Presentation
  Wiesbaden
- Data Source
  KAKENHI-PROJECT-24791396
[Presentation] Hic-5 deficiency blocks the development of angiotensin II-induced abdominal aortic aneurysms in mice2012
- Author(s)
  Xiao-Feng Lei, Joo-ri Kim-Kaneyama, Shigeko Arita, Takuro Miyazaki, Akira Miyazaki
- Organizer
  第44回日本動脈硬化学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24791396
[Presentation] Hic-5 deficiency blocks the development of angiotensin II-induced abdominal aortic aneurysms in mice2012
- Author(s)
  Xiao-Feng Lei, Joo-ri Kim-Kaneyama, Shigeko Arita, Takuro Miyazaki, Akira Miyazaki
- Organizer
  The 17th International Vascular Biology Meeting
- Place of Presentation
  Wiesbaden, Germany
- Data Source
  KAKENHI-PROJECT-24791396
[Presentation] Hic-5 deficiency inhibits the development of angiotensin II-induced aortic aneurysms2012
- Author(s)
  Xiao-Feng Lei, Joo-ri Kim-Kaneyama, Shigeko Arita, Takuro Miyazaki, Akira Miyazaki
- Organizer
  第44回日本動脈硬化学会総会・学術集会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-24791396
[Presentation] 肝線維化におけるTGF-beta 誘導分子Hic-5の機能解析
- Author(s)
  雷　小峰、付　文広、金山　朱里、大久保　茂子、宮崎　拓郎、宮崎　章
- Organizer
  第４７回日本結合組織学会学術大会
- Place of Presentation
  コクヨホール（東京都港区）
- Year and Date
  2015-05-15 – 2015-05-16
- Data Source
  KAKENHI-PROJECT-26860588

1. 金山朱里 (10338535)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
2. 宮内彩 (20882434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 坂木理 (90439414)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MIYAZAKI Takuro

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
5. NAKAMACHI Tomoya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 大塚憲一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 福田大受

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 反町洋之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 村上誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 宮崎章

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 田中篤

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 西口毅

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 松田恒平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Rai Shoho 雷 小峰

LEI Xiao-Feng 雷 小峰

Research Projects

Research Products

Co-Researchers

老化関連遺伝子を標的としたアンチセンス核酸によるMASH病態改善機構の解明

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Analysis of novel target molecules for systemic scleroderma using single cell analysis.Principal Investigator

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Novel pulmonary fibrosis therapeutic strategy targeting TGF-beta inducible genePrincipal Investigator

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Establishment of novel target molecules for pancreatic diseases by regulating stellate cell activationPrincipal Investigator

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Roles of hydrogen peroxide-induced clone 5 in pathogenesis of thoracic aortic aneurysm in marfan syndromPrincipal Investigator

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Identification of Hic-5 as a novel molecule in the development of abdominal aortic aneurysmsPrincipal Investigator

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[Journal Article] Innate Immune System Regulated by Stimulator of Interferon Genes, a Cytosolic DNA Sensor, Regulates Endothelial Function2023

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[Journal Article] Knockdown of mechanosensitive adaptor Hic-5 ameliorates post-traumatic osteoarthritis in rats through repression of MMP-132023

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[Journal Article] Hic-5 is required for activation of pancreatic stellate cells and development of pancreatic fibrosis in chronic pancreatitis2020

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[Journal Article] Alleviation of murine osteoarthritis by deletion of the focal adhesion mechanosensitive adapter, Hic-52019

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[Journal Article] Toll‐Like Receptor 9 Plays a Pivotal Role in Angiotensin II Induced Atherosclerosis2019

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NAID

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[Journal Article] Light-at-night exposure affects brain development through pineal allopregnanolone-dependent mechanisms2019

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[Journal Article] Expression of steroidogenic enzymes and metabolism of steroids in COS-7 cells known as non-steroidogenic cells.2018

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[Journal Article] The impact of stromal Hic-5 on the tumorigenesis of colorectal cancer through lysyl oxidase induction and stromal remodeling.2018

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Rai Shoho 雷小峰

LEI Xiao-Feng 雷小峰