Yamashita Kenichiro 山下謙一郎

Researcher Number	00596687
Other IDs
Affiliation (Current)	2025: 国際医療福祉大学, トランスレーショナルニューロサイエンスリサーチセンター, 准教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 国際医療福祉大学, トランスレーショナルニューロサイエンスリサーチセンター, 准教授 2021 – 2022: 国際医療福祉大学, トランスレーショナルニューロサイエンスセンター, 准教授 2018 – 2020: 九州大学, 医学研究院, 助教 2015 – 2017: 九州大学, 大学病院, 助教 2014: 九州大学, 医学(系)研究科(研究院), 助教 2012 – 2013: 久留米大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Neurology / Basic Section 52020:Neurology-related Except Principal Investigator Basic Section 52020:Neurology-related
Keywords	Principal Investigator アルツハイマー病 / 機能的MRI / 安静時機能的MRI / 認知症 / アルツハイマー型認知症 / 脳機能的ネットワーク / Resting State Network / 安静時能的MRI / 脳コネクトーム / Default Mode Network / 軽度認知障害 … More Except Principal Investigator … More microRNA / 毒性ターンアミロイドβ蛋白 / 毒性ターンAβ / マイクロRNA / エキソソーム / バイオマーカー / アルツハイマー病 / 加速的長期健忘 / 遠隔記憶障害 / 側頭葉てんかん / 睡眠 / 忘却の促進 / 記憶障害 / てんかん Less

発作間欠期てんかん性放電による記憶障害：てんかんとアルツハイマー病における検討
- Principal Investigator
  
  上原平
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  International University of Health and Welfare
毒性ターンAβ42含有エキソソームによるアルツハイマー病早期診断と病態伝搬の解明
- Principal Investigator
  
  今村友裕
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  International University of Health and Welfare
異常蛋白凝集に先行する脳機能的結合異常の検証によるアルツハイマー病発症機序の解明Principal Investigator
- Principal Investigator
  
  山下謙一郎
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  International University of Health and Welfare
  Kyushu University
Targeted memory reactivation experiments to explore the pathomechanisms of accelerated long-term forgetting in patients with epilepsy
- Principal Investigator
  
  Shigeto Hiroshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kyushu University
Brain connectome change associated with propagation of amyloid beta in Alzheimer's disease.Principal Investigator
- Principal Investigator
  
  Yamashita Kenichiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
Study of memory consolidation of Alzheimer's disease patients using fMRIPrincipal Investigator
- Principal Investigator
  
  Yamashita Kenichiro
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
  Kurume University

All 2023 2022 2020 2018 2017 2016 2014 2013

All Journal Article Presentation

[Journal Article] Long-Term Effect of Acetylcholinesterase Inhibitors on the Dorsal Attention Network of Alzheimer’s Disease Patients: A Pilot Study Using Resting-State Functional Magnetic Resonance Imaging2022
- Author(s)
  Ken-ichiro Yamashita, Taira Uehara, Yoshihide Taniwaki, Shozo Tobimatsu and Jun-ichi Kira
- Journal Title
  
  Frontiers in Aging Neuroscience
  
  Volume: 14 Pages: 1-9
- DOI
  10.3389/fnagi.2022.810206
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07888
[Journal Article] An exploratory, open-label, randomized, multicenter trial of hachimijiogan for mild Alzheimer’s disease2022
- Author(s)
  Kainuma M, Ouma S, Kawakatsu S, Iritani O, Yamashita KI, Ohara T, Hirano S, Suda S, Hamano T, Hieda S, Yasui M, Yoshiiwa A, Shiota S, Hironishi M, Wada-Isoe K, Sasabayashi D, Yamasaki S, Murata M, Funakoshi K, Hayashi K, Shirafuji N, Sasaki H, Kajimoto Y, Mori Y, Suzuki M, Ito H, Ono K, Tsuboi Y.
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 13 Pages: 991982-991982
- DOI
  10.3389/fphar.2022.991982
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07965, KAKENHI-PROJECT-20K07888, KAKENHI-PROJECT-21K07321, KAKENHI-PROJECT-22K07392, KAKENHI-PROJECT-22K07514, KAKENHI-PROJECT-22K15745, KAKENHI-PROJECT-20KK0193, KAKENHI-PROJECT-18K15509, KAKENHI-PROJECT-17K09211
[Journal Article] Disconnection of the right superior parietal lobule from the precuneus is associated with memory impairment in oldest-old Alzheimer's disease patients.2020
- Author(s)
  Prawiroharjo P, Yamashita KI, Yamashita K, Togao O, Hiwatashi A, Yamasaki R, Kira JI.
- Journal Title
  
  Heliyon
  
  Volume: ６ Issue: 7 Pages: e04516-e04516
- DOI
  10.1016/j.heliyon.2020.e04516
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07888
[Journal Article] Optic, trigeminal, and facial neuropathy related to anti-neurofascin 155 antibody.2020
- Author(s)
  Ogata H , Zhang X , Inamizu S , Yamashita K , Yamasaki R , Matsushita T, Isobe N, Hiwatashi A, Tobimatsu S, Kira J.
- Journal Title
  
  Ann Clin Transl Neurol
  
  Volume: 11 Issue: 11 Pages: 2297-2309
- DOI
  10.1002/acn3.51220
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07888, KAKENHI-PROJECT-20K16602, KAKENHI-PROJECT-19K17036
[Journal Article] The efficacy and safety of hachimijiogan for mild Alzheimer disease in an exploratory, open standard treatment controlled, randomized allocation, multicenter trial: A study protocol.2020
- Author(s)
  Kainuma M , Funakoshi K , Ouma S, Yamashita K, Ohara T, Yoshiiwa A, Murata M, Tsuboi Y.
- Journal Title
  
  Medicine (Baltimore)
  
  Volume: 99 Issue: 38 Pages: e22370-e22370
- DOI
  10.1097/md.0000000000022370
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07888
[Journal Article] Functional connectivity change between posterior cingulate cortex and ventral attention network relates to the impairment of orientation for time in Alzheimer’s disease patients2018
- Author(s)
  Yamashita Ken-ichiro、Uehara Taira、Prawiroharjo Pukovisa、Yamashita Koji、Togao Osamu、Hiwatashi Akio、Taniwaki Yoshihide、Utsunomiya Hidetsuna、Matsushita Takuya、Yamasaki Ryo、Kira Jun-ichi
- Journal Title
  
  Brain Imaging and Behavior
  
  Volume: 印刷中 Issue: 1 Pages: 154-161
- DOI
  10.1007/s11682-018-9860-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19491, KAKENHI-PROJECT-17K09802, KAKENHI-PROJECT-18K07530, KAKENHI-INTERNATIONAL-15K21731, KAKENHI-ORGANIZER-15H05871, KAKENHI-PLANNED-15H05875, KAKENHI-PROJECT-16K09722
[Journal Article] Functional connectivity change between posterior cingulate cortex and ventral attention network relates to the impairment of orientation for time in Alzheimer's disease patients.2018
- Author(s)
  Yamashita KI, Uehara T, Prawiroharjo P, Yamashita K, Togao O, Hiwatashi A, Taniwaki Y, Utsunomiya H, Matsushita T, Yamasaki R, Kira JI.
- Journal Title
  
  Brain imaging and behavior
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09353
[Journal Article] A case of multiple system atrophy-parkinsonian type with stuttering- and palilalia-like dysfluencies and putaminal atrophy.2017
- Author(s)
  Kikuchi Y, Umezaki T, Uehara T, Yamaguchi H, Yamashita K, Hiwatashi A, Sawatsubashi M, Adachi K, Yamaguchi Y, Murakami D, Kira JI, Nakagawa T.
- Journal Title
  
  J Fluency Disord.
  
  Volume: 14 Pages: 51-58
- DOI
  10.1016/j.jfludis.2017.11.002
- NAID
  120006956773
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16922, KAKENHI-PROJECT-17K09802, KAKENHI-PROJECT-18K07530, KAKENHI-INTERNATIONAL-15K21731, KAKENHI-ORGANIZER-15H05871, KAKENHI-PLANNED-15H05875
[Journal Article] Cerebral blood flow reduction associated with orientation for time in amnesic mild cognitive impairment and Alzheimer disease patients.2014
- Author(s)
  Yamashita K, Taniwaki Y, Utsunomiya H, Taniwaki T.
- Journal Title
  
  J Neuroimaging
  
  Volume: 24 Issue: 6 Pages: 590-4
- DOI
  10.1111/jon.12096
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591298, KAKENHI-PROJECT-24591306
[Journal Article] Disrupted connectivityofmotorloopsinParkinson’s disease duringself-initiatedbutnot externally-triggeredmovements2013
- Author(s)
  Takayuki Taniwaki
- Journal Title
  
  Brain research
  
  Volume: 1512 Pages: 45-49
- DOI
  10.1016/j.brainres.2013.03.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591298, KAKENHI-PROJECT-24591306, KAKENHI-PROJECT-25351000
[Presentation] アルツハイマー病における大脳皮質萎縮と脳機能的結合変化の関連の検討2023
- Author(s)
  山下謙一郎
- Organizer
  第42回認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07888
[Presentation] グリアコネキシン低分子量イソフォーム発現エクソソームによる多発性硬化症の増悪機序2022
- Author(s)
  中村優理、グザリアイ・ママティジャン、今村友裕、柳原由記、岩永育貴、山下謙一郎、張旭、吉良潤一
- Organizer
  第12回国際医療福祉大学学会学術大会
- Data Source
  KAKENHI-PROJECT-22K07499
[Presentation] Foot-dorsiflexion power on the dominant hand side is useful to predict multiple sclerosis disability2022
- Author(s)
  Jun-ichi Kira, Ayako Sakoda, Yoshie Yamato, Yuki Yanagihara, Ban-yu Saitoh, Yasutaka Iwanaga, Kenichiro Yamashita, Guzailiayi Maimaitijiang, Tomohiro Imamura, Xu Zhang, Shozo Tobimatsu, Yuri Nakamura
- Organizer
  第63回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-22K07499
[Presentation] GIFTソフトウェアよるアルツハイマー病治療薬での脳機能的結合変化の研究2022
- Author(s)
  山下謙一郎
- Organizer
  第41回認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07888
[Presentation] 血清エキソソーム中のマイクロRNAによるアルツハイマー病の早期診断バイオマーカー2022
- Author(s)
  今村友裕、柳原由記、山下謙一郎、張旭、グザリアイママティジャン、満石三喜男、吉良潤一
- Organizer
  第12回国際医療福祉大学学会学術大会
- Data Source
  KAKENHI-PROJECT-22K07499
[Presentation] 安静時機能的MRIを用いたアルツハイマー病治療薬による脳機能的結合変化の研究2020
- Author(s)
  山下謙一郎、上原平、菊池一史、栂尾理、樋渡昭雄、飛松省三
- Organizer
  第39回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07888
[Presentation] Functional connectivity changes related to cognitive improvement by acetylcholine esterase inhibiters in Alzheimer disease2017
- Author(s)
  Ken-ichiro Yamashita
- Organizer
  The XXIII World Congress of Neurology (WCN 2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09353
[Presentation] アルツハイマー病での時間見当識障害に伴う脳機能的ネットワーク結合変化の研究2016
- Author(s)
  山下謙一郎
- Organizer
  第30回日本認知症学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-15K09353
[Presentation] アルツハイマー病の時間見当識障害による脳機能的結合変化の安静時機能的MRI研究2016
- Author(s)
  山下謙一郎
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-15K09353
[Presentation] SPECTによる軽度認知障害からアルツハイマー型認知症への移行の後ろ向き研究2014
- Author(s)
  山下謙一郎, 谷脇予志秀，宇都宮英綱, 谷脇考恭
- Organizer
  第55回日本神経学会学術大会
- Place of Presentation
  福岡
- Year and Date
  2014-05-23
- Data Source
  KAKENHI-PROJECT-24591298

1. 上原平 (30631585)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
2. Shigeto Hiroshi (50335965)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 緒方勝也 (50380613)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 今村友裕 (30725122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. 大八木保政 (30301336)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 吉良潤一 (40183305)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. 菊池良和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 小野賢二郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamashita Kenichiro 山下 謙一郎

Research Projects

Research Products

Co-Researchers

発作間欠期てんかん性放電による記憶障害：てんかんとアルツハイマー病における検討

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

毒性ターンAβ42含有エキソソームによるアルツハイマー病早期診断と病態伝搬の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

異常蛋白凝集に先行する脳機能的結合異常の検証によるアルツハイマー病発症機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Targeted memory reactivation experiments to explore the pathomechanisms of accelerated long-term forgetting in patients with epilepsy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Brain connectome change associated with propagation of amyloid beta in Alzheimer's disease.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of memory consolidation of Alzheimer's disease patients using fMRIPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Long-Term Effect of Acetylcholinesterase Inhibitors on the Dorsal Attention Network of Alzheimer’s Disease Patients: A Pilot Study Using Resting-State Functional Magnetic Resonance Imaging2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An exploratory, open-label, randomized, multicenter trial of hachimijiogan for mild Alzheimer’s disease2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Disconnection of the right superior parietal lobule from the precuneus is associated with memory impairment in oldest-old Alzheimer's disease patients.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Optic, trigeminal, and facial neuropathy related to anti-neurofascin 155 antibody.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The efficacy and safety of hachimijiogan for mild Alzheimer disease in an exploratory, open standard treatment controlled, randomized allocation, multicenter trial: A study protocol.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Functional connectivity change between posterior cingulate cortex and ventral attention network relates to the impairment of orientation for time in Alzheimer’s disease patients2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Functional connectivity change between posterior cingulate cortex and ventral attention network relates to the impairment of orientation for time in Alzheimer's disease patients.2018

Author(s)

Journal Title

Data Source

[Journal Article] A case of multiple system atrophy-parkinsonian type with stuttering- and palilalia-like dysfluencies and putaminal atrophy.2017

Author(s)

Journal Title

DOI

NAID

Data Source

Yamashita Kenichiro 山下謙一郎