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OKURA Dan  大倉 暖

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OOKURA Dan  大倉 暖

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Researcher Number 00596710
Affiliation (based on the past Project Information) *help 2014 – 2017: 産業医科大学, 医学部, 助教
2012: 産業医科大学, 医学部, 産業医学修練医
2011: 産業医科大学, 医学部, 研究員
Review Section/Research Field
Principal Investigator
Anesthesiology
Except Principal Investigator
Anesthesiology/Resuscitation studies / Anesthesiology
Keywords
Principal Investigator
新たな鎮痛薬開発 / ニューロステロイド / P2X7受容体抑制機構 / P2X7受容体 / ATP受容体 / 難治性慢性疼痛
Except Principal Investigator
新たな鎮痛薬開発 / 神経障害性疼痛 / アフリカツメガエル卵母細胞発現系 / 内因性カンナビノイド … More / 抗うつ薬 / TRPA1受容体 / TRPM8受容体 / 温度感受性受容体 / 冷感アロディニア / Nav1.3選択的阻害薬 / Nav1.3サブユニット / 電位依存性ナトリウムチャネル / 疼痛抑制機序の解明 / アナンダマイド / P2X受容体 / 全身麻酔薬 / 癌性疼痛 / 鎮痛薬 / P2X_7受容体 / P2X_4受容体 / 疼痛発現機構 / サブユニット選択的作用 / P2X7受容体 / ATP受容体 / 疹痛管理学 / 疼痛機構 / PS / 麻酔作用 / ニユーロステロイド / ニューロステロイド / アロプレグナノロン / プレグナノロン / 作用機序 / 疼痛機序 / 鎮痛作用 / ニューステロイド / ナトリウムチャネル / 疼痛管理学 Less
  • Research Projects

    (6 results)
  • Research Products

    (7 results)
  • Co-Researchers

    (4 People)
  •  Elucidation of the mechanisms underlying inhibition of the function of P2X7 receptor aimed at development of novel analgesics for refractory chromic painPrincipal Investigator

    • Principal Investigator
      OKURA Dan
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Anesthesiology
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Elucidation of the mechanisms underlying inhibition of TRPM8 receptor aimed at development of novel analgesics to treat cold allodynia

    • Principal Investigator
      HORISHITA Takafumi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Analysis of the mechanisms underlying inhibition of voltage-gated sodium channel aimed at development of selective inhibitor on Nav1.3

    • Principal Investigator
      SATA Takeyoshi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Analysis of the mechanisms of pain relief by endocannabinoids aimed at development of analgesics for neuropathic pain

    • Principal Investigator
      HORISHITA Takafumi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Investigations of painmechanism related to ATP receptors aiming at new analgesics for cancer pain

    • Principal Investigator
      SATA Takeyoshi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Analysis of the action mechanisms of volatile anesthetics and analgesics aimed at development of selective sodium channel blocker

    • Principal Investigator
      HORISHITA Takafumi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan

All 2017 2015 2014 2013

All Journal Article Presentation

  • [Journal Article] The endocannabinoid anandamide inhibits voltage-gated sodium channels NaV1.2, NaV1.6, NaV1.7 and NaV1.8 in Xenopus Oocytes.2014

    • Author(s)
      Okura D, Horishita T, Ueno S, Yanagihara N, Sudo Y, Uezono Y, Sata T.
    • Journal Title

      Anesth Analg

      Volume: 118 Issue: 3 Pages: 554-562

    • DOI

      10.1213/ane.0000000000000070

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590740, KAKENHI-PROJECT-24592369, KAKENHI-PROJECT-25860200
  • [Presentation] Lidocaine inhibits 2APB-induced currents of TRPV3 channels expressed in Xenopus oocytes2017

    • Author(s)
      Reiko Horishita, Takafumi Horishita, Dan Okura, Tomoko Minami, Yuichi Ogata, Takashi Kawasaki
    • Organizer
      2017 Annual meeting, American Society of Anesthesiologists
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10567
  • [Presentation] 温度感受性TRPチャネルサブファミリー、TRPA1に対するガバペンチンの影響2015

    • Author(s)
      土山玲子、堀下貴文、大倉暖、南智子、佐多竹良
    • Organizer
      日本麻酔科学会第62回学術集会
    • Place of Presentation
      神戸国際展示場(兵庫県神戸市)
    • Year and Date
      2015-05-28
    • Data Source
      KAKENHI-PROJECT-15K10567
  • [Presentation] アロプレグナノロン硫酸塩は、ATP受容体サブタイプ、P2X7受容体機能を抑制する2015

    • Author(s)
      大倉暖、堀下貴文、土山玲子、南智子、佐多竹良
    • Organizer
      日本麻酔科学会第62回学術集会
    • Place of Presentation
      神戸ポートピアホテル(兵庫県神戸市)
    • Year and Date
      2015-05-28
    • Data Source
      KAKENHI-PROJECT-15K20065
  • [Presentation] カルバクロールは、電位依存性ナトリウムチャネルαサブユニット、Nav1.2、Nav1.3、Nav1.6、Nav1.7、Nav1.8機能を抑制する2015

    • Author(s)
      堀下貴文、大倉暖、土山玲子、南智子、熊倉美佳、佐多竹良
    • Organizer
      日本麻酔科学会第62回学術集会
    • Place of Presentation
      神戸ポートピアホテル(兵庫県神戸市)
    • Year and Date
      2015-05-28
    • Data Source
      KAKENHI-PROJECT-25462462
  • [Presentation] リドカインはATP受容体サブタイプ、P2×_7受容体機能を抑制する2013

    • Author(s)
      大倉暖、堀下貴文、佐多竹良
    • Organizer
      日本麻酔科学会第60回学術集会
    • Place of Presentation
      札幌(ロイトン札幌)
    • Year and Date
      2013-05-23
    • Data Source
      KAKENHI-PROJECT-22591756
  • [Presentation] リドカインはATP受容体サブタイプ、P2X7受容体機能を抑制する2013

    • Author(s)
      大倉暖
    • Organizer
      日本麻酔科学会第60回学術集会
    • Place of Presentation
      札幌(ロイトン札幌)
    • Data Source
      KAKENHI-PROJECT-22591756
  • 1.  HORISHITA Takafumi (40369070)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 4 results
  • 2.  SATA Takeyoshi (60128030)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 3 results
  • 3.  HORISHITA Reiko (40746658)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 4.  上園 保仁
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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