TATEBE Hisashi 建部恒

Researcher Number	00596819
Other IDs
Affiliation (based on the past Project Information) *help	2018 – 2020: 奈良先端科学技術大学院大学, 先端科学技術研究科, 助教 2011 – 2017: 奈良先端科学技術大学院大学, バイオサイエンス研究科, 助教
Review Section/Research Field	Principal Investigator Cell biology / Basic Section 43030:Functional biochemistry-related Except Principal Investigator Molecular biology / Functional biochemistry
Keywords	Principal Investigator TORC2 / 分裂酵母 / Rab低分子量Gタンパク質 / グルコース / Target Of Rapamycin / TOR / 国際情報交流 / Ｇタンパク質 / Gタンパク質 / Akt … More Except Principal Investigator … More Mre11 / 二本鎖DNA切断 / 相同組換え / 高速AFM / DNA二本鎖切断 / DNA修復 / 細胞情報伝達機構機構 / 細胞情報伝達機構 / TORC2 / TORC1 / 細胞増殖 / 栄養源 / 分裂酵母 / TOR Less

TORキナーゼ複合体２（TORC2）活性化分子機構の解明Principal Investigator
- Principal Investigator
  
  建部恒
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Nara Institute of Science and Technology
Biochemical analysis of Human Mre11 complex working in DNA double-strand break repair
- Principal Investigator
  
  Furukohri Asako
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Osaka University
  Nara Institute of Science and Technology
TOR kinase complexes that sense and integrate major nutritional signals
- Principal Investigator
  
  Shiozaki Kazuhiro
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Nara Institute of Science and Technology
Reguratory mechanism of TOR Complex 2 on glucose stimuliPrincipal Investigator
- Principal Investigator
  
  Tatebe Hisashi
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Nara Institute of Science and Technology
Regulatory mechanism of TOR signaling in response to glucosePrincipal Investigator
- Principal Investigator
  
  TATEBE Hisashi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  Nara Institute of Science and Technology

All 2020 2019 2017 2016 2015 2013 2012 Other

All Journal Article Presentation Book

[Book] "PP2C" in Encyclopedia of Signaling Molecules, 2nd Edition2017
- Author(s)
  Tatebe H, Shiozaki K
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-26291024
[Book] In Encyclopedia of Signaling Molecules2012
- Author(s)
  Tatebe, H., and Shiozaki, K
- Publisher
  New York: Springer
- Data Source
  KAKENHI-PROJECT-23770230
[Book] PP2C. In Encyclopedia of Signaling Molecules, S. Choi, eds. 10.1007/978-1-4419-0461-4_2492012
- Author(s)
  Tatebe H
- Total Pages
  4
- Publisher
  New York: Springer
- Data Source
  KAKENHI-PROJECT-23770230
[Journal Article] Rad50 zinc hook functions as a constitutive dimerization module interchangeable with SMC hinge2020
- Author(s)
  Tatebe Hisashi、Lim Chew Theng、Konno Hiroki、Shiozaki Kazuhiro、Shinohara Akira、Uchihashi Takayuki、Furukohri Asako
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 370-370
- DOI
  10.1038/s41467-019-14025-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06542, KAKENHI-PROJECT-19K06596, KAKENHI-PLANNED-15H05973, KAKENHI-PUBLICLY-18H04512, KAKENHI-PUBLICLY-19H05389, KAKENHI-PROJECT-18H01837, KAKENHI-PROJECT-16K07255, KAKENHI-PROJECT-19H00981, KAKENHI-PROJECT-23K20059
[Journal Article] Evolutionary Conservation of the Components in the TOR Signaling Pathways.2017
- Author(s)
  Tatebe, H., and Shiozaki, K.
- Journal Title
  
  Biomolecules
  
  Volume: 7 Issue: 4 Pages: 77-77
- DOI
  10.3390/biom7040077
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291024
[Journal Article] Substrate specificity of TOR complex 2 is determined by a ubiquitin-fold domain of the Sin1 subunit2017
- Author(s)
  Hisashi Tatebe, Shinichi Murayama, Toshiya Yonekura, Tomoyuki Hatano, David Richter, Tomomi Furuya, Saori Kataoka, Kyoko Furuita, Chojiro Kojima, and Kazuhiro Shiozaki
- Journal Title
  
  eLife
  
  Volume: 6
- DOI
  10.7554/elife.19594
- NAID
  120005983409
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291013, KAKENHI-PROJECT-26291024, KAKENHI-PROJECT-25440086, KAKENHI-PROJECT-16K14681
[Journal Article] Fission yeast Ryh1 GTPase activates TOR Complex 2 in response to glucose2015
- Author(s)
  Tomoyuki Hatano, Susumu Morigasaki, Hisashi Tatebe, Kyoko Ikeda, Kazuhiro Shiozaki
- Journal Title
  
  Cell Cycle
  
  Volume: 14 Issue: 6 Pages: 848-856
- DOI
  10.1080/15384101.2014.1000215
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25440086, KAKENHI-PROJECT-26440099, KAKENHI-PROJECT-26291024
[Journal Article] A Photo-triggerable Drug Carrier Based on Cleavage of PEG lipids by Photosensitiser-generated Reactive Singlet Oxygen2013
- Author(s)
  C. Komeda, A. Ikeda, J. Kikuchi, N. Ishida-Kitagawa, H. Tatebe, K. Shiozaki, M. Akiyama
- Journal Title
  
  Org. Biomol. Chem
  
  Volume: Vol.11, No.16 Issue: 16 Pages: 2567-2570
- DOI
  10.1039/c2ob27199k
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20108013, KAKENHI-PROJECT-23592214, KAKENHI-PROJECT-23770230, KAKENHI-PROJECT-23870019, KAKENHI-PROJECT-24655128, KAKENHI-PROJECT-25288037
[Journal Article] Response regulator-mediated MAPKKK heteromer promotes stress signaling to the Spc1 MAPK in fission yeast2013
- Author(s)
  Morigasaki, S., Ikner, A., Tatebe, H., and Shiozaki, K.
- Journal Title
  
  Mol Biol Cell
  
  Volume: 24 Issue: 7 Pages: 1083-92
- DOI
  10.1091/mbc.e12-10-0727
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770230, KAKENHI-PROJECT-23870019, KAKENHI-PROJECT-24570217
[Journal Article] Cyclodextrin Complexed [60]Fullerene Derivatives with High Levels of Photodynamic Activity by Long Wavelength Excitation.2013
- Author(s)
  Ikeda A, Iizuka T, Maekubo N, Aono R, Kikuchi J, Akiyama M, Konishi T, Ogawa T, Ishida-Kitagawa N, Tatebe H, Shiozaki K
- Journal Title
  
  ACS Medicinal Chemistry Letters
  
  Volume: 4 Issue: 8 Pages: 752-756
- DOI
  10.1021/ml4001535
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592214, KAKENHI-PROJECT-24614007, KAKENHI-PROJECT-24655128, KAKENHI-PROJECT-25288037, KAKENHI-PROJECT-25440086
[Presentation] Roles of the Sin1 subunit of TOR Complex 2 (TORC2)2019
- Author(s)
  Hisashi Tatebe
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K06542
[Presentation] 細胞外環境に応答したTORキナーゼ複合体２の活性化メカニズム2017
- Author(s)
  建部恒、森ヶ崎進、両角祐一、塩崎一裕
- Organizer
  日本遺伝学会第89回大会
- Data Source
  KAKENHI-PROJECT-26291024
[Presentation] 酵母Greatwallプロテインキナーゼを介したアルコール発酵調節経路2017
- Author(s)
  梶原拓真、渡辺大輔、武田鋼二郎、建部恒、塩﨑一裕、高木博史
- Organizer
  酵母遺伝学フォーラム第50回研究報告会
- Data Source
  KAKENHI-PROJECT-26291024
[Presentation] 分裂酵母GATOR1-Gtr1経路によるTORC1活性制御機構の解析2016
- Author(s)
  松田　崇斗、Chia Kim Hou、Fajar Sofyantro、天井貴光、福田智行、建部恒、塩﨑一裕
- Organizer
  酵母遺伝学フォーラム第49回研究報告会
- Place of Presentation
  ホテル舞子ビラ（兵庫県神戸市）
- Year and Date
  2016-09-09
- Data Source
  KAKENHI-PROJECT-26291024
[Presentation] Rag GTPase二量体によるTOR複合体１経路の抑制は分裂酵母の増殖に重要である2015
- Author(s)
  福田智行、建部恒、塩崎一裕
- Organizer
  日本分子生物学会・日本生化学会　合同大会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26291024
[Presentation] Negative regulation of TOR complex 1 by heterodimeric Gtr1-Gtr2 GTPases2015
- Author(s)
  Tomoyuki Fukuda, Hisashi Tatebe, Kazuhiro Shiozaki
- Organizer
  The 8th International Fission Yeast Meeting
- Place of Presentation
  生田神社会館（兵庫県神戸市）
- Year and Date
  2015-06-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291024
[Presentation] Role of Sin1 in TORC2 signaling2013
- Author(s)
  Hisashi Tatebe
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸国際会議場
- Invited
- Data Source
  KAKENHI-PROJECT-25440086
[Presentation] 分裂酵母TORキナーゼ複合体はスフィンゴ脂質生合成の制御に関与する
- Author(s)
  江森翠、秦野智行、建部恒、塩崎一裕
- Organizer
  酵母遺伝学フォーラム第47回研究報告会
- Place of Presentation
  東京大学弥生講堂（東京都文京区）
- Year and Date
  2014-09-01 – 2014-09-03
- Data Source
  KAKENHI-PROJECT-26291024
[Presentation] Regulation of TOR Complex 2 (TORC2) and its physiological roles in response to the extracellular environment
- Author(s)
  Hisashi Tatebe, Tomoyuki Hatano, Susumu Morigasaki, Midori Emori, Kazuhiro Shiozaki
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25440086
[Presentation] Recognition of AGC kinase by TOR complex 2
- Author(s)
  建部　恒
- Organizer
  第34回日本分子生物学会年会(招待講演)
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23770230
[Presentation] TORキナーゼ複合体2(TORC2)の環境応答制御とその生理的意義
- Author(s)
  建部恒、秦野智行、森ヶ崎進、江森翠、塩崎一裕
- Organizer
  日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-26291024

1. Shiozaki Kazuhiro (00610015)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
2. FUKUDA Tomoyuki (90415282)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. KOJIMA Chojiro (50333563)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. Furukohri Asako (90546293)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. FURUITA Kyoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 菊池純一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 石田教弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TATEBE Hisashi 建部 恒

Research Projects

Research Products

Co-Researchers

TORキナーゼ複合体２（TORC2）活性化分子機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Biochemical analysis of Human Mre11 complex working in DNA double-strand break repair

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

TOR kinase complexes that sense and integrate major nutritional signals

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Reguratory mechanism of TOR Complex 2 on glucose stimuliPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulatory mechanism of TOR signaling in response to glucosePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] "PP2C" in Encyclopedia of Signaling Molecules, 2nd Edition2017

Author(s)

Publisher

Data Source

[Book] In Encyclopedia of Signaling Molecules2012

Author(s)

Publisher

Data Source

[Book] PP2C. In Encyclopedia of Signaling Molecules, S. Choi, eds. 10.1007/978-1-4419-0461-4_2492012

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Rad50 zinc hook functions as a constitutive dimerization module interchangeable with SMC hinge2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evolutionary Conservation of the Components in the TOR Signaling Pathways.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Substrate specificity of TOR complex 2 is determined by a ubiquitin-fold domain of the Sin1 subunit2017

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Fission yeast Ryh1 GTPase activates TOR Complex 2 in response to glucose2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Photo-triggerable Drug Carrier Based on Cleavage of PEG lipids by Photosensitiser-generated Reactive Singlet Oxygen2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Response regulator-mediated MAPKKK heteromer promotes stress signaling to the Spc1 MAPK in fission yeast2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cyclodextrin Complexed [60]Fullerene Derivatives with High Levels of Photodynamic Activity by Long Wavelength Excitation.2013

Author(s)

TATEBE Hisashi 建部恒