Ishima Tamaki 石間環

… Alternative Names

石間環イシマタマキ

ISHIMA Tamaki 石間環

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Researcher Number	00597130
Other IDs
Affiliation (Current)	2025: 自治医科大学, 医学部, ポスト・ドクター
Affiliation (based on the past Project Information) *help	2023: 千葉大学, 社会精神保健教育研究センター, 特任助教 2022 – 2023: 自治医科大学, 医学部, ポスト・ドクター 2021: 千葉大学, 社会精神保健教育研究センター, 特任助教 2018 – 2019: 千葉大学, 社会精神保健教育研究センター, 特任助教 2016: 千葉大学, 社会精神保健教育研究センター, 特任助教 2011 – 2012: 千葉大学, 社会精神保健教育研究センター, 特任研究員
Review Section/Research Field	Principal Investigator 0903:Organ-based internal medicine and related fields / Basic Section 52030:Psychiatry-related / Psychiatric science Except Principal Investigator Basic Section 52030:Psychiatry-related / Biological Sciences / Psychiatric science
Keywords	Principal Investigator マルチオミックス / 大動脈解離 / 肝細胞 / iPS / 双極性障害 / IP3受容体 / 熱ストレスタンパク質 / カルシウムシグナリング / アリピプラゾール / 神経突起伸長 / 精神薬理学 … More Except Principal Investigator … More 脳由来神経栄養因子 / ケタミン / ストレス / うつ病 / 脳神経疾患 / 脳・神経疾患 / うう病 / 抗うつ作用 / 光学異性体 / 抗うつ効果 / 腸内細菌 / 予防効果 / 骨密度 / 炎症 / レジリエンス / アールケタミン / 腸-脳相関 / ミエリン / 抗うつ薬 / D型セリン / ＮＭＤＡ受容体 / グルタミン酸神経系 / TrkB受容体 / スパイン / グルタミン酸 / 薬理学 / 神経科学 / Dセリン / NMDA受容体 / 統合失調症 / ミトコンドリア / クエン酸回路 / バイオマーカー / 双極性障害 Less

マルチオミックス解析を駆使した家族性大動脈瘤・解離の素因解明Principal Investigator
- Principal Investigator
  
  石間環
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0903:Organ-based internal medicine and related fields
- Research Institution
  Jichi Medical University
Study of molecular mechanisms underlying antidepressant actions of (R)-ketamine
- Principal Investigator
  
  Hashimoto Kenji
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Chiba University
Study on the etiology of bipolar disorder using iPS cellsPrincipal Investigator
- Principal Investigator
  
  ISHIMA Tamaki
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Chiba University
Metabolomics analysis of CSF from bipolar disorder patients
- Principal Investigator
  
  Kenji Hashimoto
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Psychiatric science
- Research Institution
  Chiba University
Microendophenotype of psychiatric disorders by glutamatergic signal
- Principal Investigator
  
  Kenji Hashimoto
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba University
Study on potentiation of neurite outgrowth by an atypical antipsychoticPrincipal Investigator
- Principal Investigator
  
  ISHIMA Tamaki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Chiba University

All 2023 2022 2016 2012

All Journal Article Presentation

[Journal Article] Multi-Omics of Familial Thoracic Aortic Aneurysm and Dissection: Calcium Transport Impairment Predisposes Aortas to Dissection2023
- Author(s)
  Shota Tomida, Tamaki Ishima, Daigo Sawaki, Yasushi Imai, Ryozo Nagai, Kenichi Aizawa
- Journal Title
  
  International Journal of Molecular Science
  
  Volume: 24 Issue: 20 Pages: 15213-15213
- DOI
  10.3390/ijms242015213
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22932, KAKENHI-PROJECT-22K20922, KAKENHI-PROJECT-21K08086
[Journal Article] Nuclear factor of activated T cells 4 in the prefrontal cortex is required for prophylactic actions of (R)-ketamine2022
- Author(s)
  Ma L, Zhang J, Fujita Y, Qu Y, Shan J, Wan X, Wang X, Ishima T, Kobayashi K, Wang L, Hashimoto K.
- Journal Title
  
  Transl Psychaitry
  
  Volume: 12(1) Issue: 1 Pages: 27-27
- DOI
  10.1038/s41398-022-01803-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02846
[Journal Article] Cerebrospinal fluid metabolomics identifies a key role of isocitrate dehydrogenase in bipolar disorder: Evidence in support of mitochondrial dysfunction hypothesis.2016
- Author(s)
  11.Yoshimi N, Futamura T, Bergen SE, Iwayama Y, Ishima T, Sellgren C, Ekman CJ, Jakobsson J, Pålsson E, Kakumoto K, Ohgi Y, Yoshikawa T, Landén M, Hashimoto K
- Journal Title
  
  Molecular Psychiatry
  
  Volume: 印刷中 Issue: 11 Pages: 1504-1510
- DOI
  10.1038/mp.2015.217
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15423, KAKENHI-PLANNED-24116002, KAKENHI-ORGANIZER-24116001
[Journal Article] Neurite outgrowth mediated by the heat shock protein Hsp90α: a novel target for the antipsychotic drug aripiprazole.2012
- Author(s)
  Tamaki Ishima
- Journal Title
  
  Translational Psychiatry
  
  Volume: 2 Issue: 10 Pages: e170-e170
- DOI
  10.1038/tp.2012.97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791308, KAKENHI-PROJECT-24659143
[Journal Article] Potentiation of nerve growth factor-induced neurite outgrowth in PC12 cells by ifenprodil: the role of sigma-1 and IP3 receptors.2012
- Author(s)
  Tamaki Ishima
- Journal Title
  
  PLoS One.
  
  Volume: 7(5) Issue: 5 Pages: e37989-e37989
- DOI
  10.1371/journal.pone.0037989
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791308, KAKENHI-PROJECT-24659143
[Presentation] 脳脊髄液のメタボロミクス解析による双極性障害におけるイソクエン酸デヒドロゲナーゼの異常2016
- Author(s)
  278.吉見典子、二村隆史、ベルゲン　サラ、岩山佳美、セルグレン　カール、エクマン　カール、ジャコブソン　ジョエル、ポルソン　エリック、石間　環、角元慶二、大木雄太、菊池哲郎、吉川武男、ランデン　ミカエル、橋本謙二
- Organizer
  第46回日本神経精神薬理学会
- Place of Presentation
  韓国ソウル市
- Year and Date
  2016-07-02
- Data Source
  KAKENHI-PROJECT-15K15423
[Presentation] Potentiation of nerve growth factor-induced neurite outgrowth in PC12 cells by aripiprazole2012
- Author(s)
  Tamaki Ishima, Masaomi Iyo and Kenji Hashimoto
- Organizer
  28^<th> CINP WORLD CONGRESS OF NEUROPSYCHOPHARMACOLOGY
- Place of Presentation
  Stockholm Sweden
- Data Source
  KAKENHI-PROJECT-23791308
[Presentation] Potentiation of nerve growth factor-induced neurite outgrowth in PC12 cells by aripiprazole2012
- Author(s)
  Tamaki Ishima
- Organizer
  28th CINP WORLD CONGRESS OF NEUROPSYCHOPHARMACOLOGY
- Place of Presentation
  Stockholm Sweden
- Data Source
  KAKENHI-PROJECT-23791308

1. Kenji Hashimoto (10189483)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
2. FUJITA Yuko (40623591)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. 澤城大悟

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ishima Tamaki 石間 環

石間 環 イシマ タマキ

ISHIMA Tamaki 石間 環

Research Projects

Research Products

Co-Researchers

マルチオミックス解析を駆使した家族性大動脈瘤・解離の素因解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study of molecular mechanisms underlying antidepressant actions of (R)-ketamine

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study on the etiology of bipolar disorder using iPS cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Metabolomics analysis of CSF from bipolar disorder patients

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Microendophenotype of psychiatric disorders by glutamatergic signal

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study on potentiation of neurite outgrowth by an atypical antipsychoticPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Multi-Omics of Familial Thoracic Aortic Aneurysm and Dissection: Calcium Transport Impairment Predisposes Aortas to Dissection2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nuclear factor of activated T cells 4 in the prefrontal cortex is required for prophylactic actions of (R)-ketamine2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cerebrospinal fluid metabolomics identifies a key role of isocitrate dehydrogenase in bipolar disorder: Evidence in support of mitochondrial dysfunction hypothesis.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neurite outgrowth mediated by the heat shock protein Hsp90α: a novel target for the antipsychotic drug aripiprazole.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Potentiation of nerve growth factor-induced neurite outgrowth in PC12 cells by ifenprodil: the role of sigma-1 and IP3 receptors.2012

Author(s)

Journal Title

DOI

Data Source

[Presentation] 脳脊髄液のメタボロミクス解析による双極性障害におけるイソクエン酸デヒドロゲナーゼの異常2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Potentiation of nerve growth factor-induced neurite outgrowth in PC12 cells by aripiprazole2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Potentiation of nerve growth factor-induced neurite outgrowth in PC12 cells by aripiprazole2012

Author(s)

Ishima Tamaki 石間環

石間環イシマタマキ

ISHIMA Tamaki 石間環