Nakayama Rumi 中山留美 (直野留美)

Connect your ORCID iD *help

… Alternative Names

Nakayama-Naono Rumi 中山留美

直野留美

中山留美(直野留美) ナカヤマルミ

NAKAYAMA Rumi 中山留美

NAONO Rumi 直野留美

Less

Researcher Number	00609034
Other IDs
Affiliation (Current)	2025: 東北医科薬科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2017 – 2024: 東北医科薬科大学, 医学部, 助教 2016: 宮崎大学, 医学部, 特別研究員 2014 – 2015: 宮崎大学, 医学部, 特別研究員(PD) 2012: 宮崎大学, 医学部, 研究員 2008: 日本学術振興会, 特別研究員
Review Section/Research Field	Principal Investigator Pain science / Basic Section 47060:Clinical pharmacy-related / Basic Section 51030:Pathophysiologic neuroscience-related Except Principal Investigator 疼痛学 / Pain science
Keywords	Principal Investigator 痒み / 神経ペプチド / 受容体 / 脊髄 / 痛み / 診断薬 / サブスタンスP / 検査薬 / 生理活性ペプチド / バイオマーカー … More / 皮膚 / Gタンパク共役型受容体 / 神経伝達物質 / GPR83 / オーファン受容体 / ヘモキニン-1 / 掻痒 / 疼痛 … More Except Principal Investigator 神経薬理 / 脊髄 / ペプチド / 疼痛 / 脳・神経 / 熱痛覚過敏 / 引っ掻き行動 / 生理活性 / 神経科学 Less

Evaluation of novel biomarkers using peptides in pruritic processingPrincipal Investigator
- Principal Investigator
  
  中山留美 (直野留美)
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Tohoku Medical and Pharmaceutical University
Role of GPR83 and related molecules for antipruritus drugsPrincipal Investigator
- Principal Investigator
  
  Nakayama-Naono Rumi
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Tohoku Medical and Pharmaceutical University
Functional association with GPR83 and other itch receptors in the spinal cordPrincipal Investigator
- Principal Investigator
  
  Nakayama Rumi
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Tohoku Medical and Pharmaceutical University
  University of Miyazaki
New tachykinin receptor mediates pruriceptive processing in the spinal cordPrincipal Investigator
- Principal Investigator
  
  Nakayama-Naono Rumi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pain science
- Research Institution
  University of Miyazaki
ヘモキニン－１由来ペプチドの疼痛および掻痒治療薬の開発に関する基礎的研究Principal Investigator
- Principal Investigator
  
  中山留美(直野留美)
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pain science
- Research Institution
  University of Miyazaki
Study on structure and function of novel tachykinin peptides
- Principal Investigator
  
  NISHIMORI Toshikazu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  疼痛学
- Research Institution
  University of Miyazaki
Studies on the contribution of novel tachykinin peptides to the pain system
- Principal Investigator
  
  NISHIMORI Toshikazu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  University of Miyazaki

[Journal Article] 痒み伝達におけるタキキニンペプチドの役割2023
- Author(s)
  中山－直野留美, 安保明博 , 生田和史 , 上条桂樹 , 船橋英樹
- Journal Title
  
  アレルギーの臨床
  
  Volume: 43 Pages: 647-650
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07828
[Journal Article] Contribution of astrocytic histamine N-methyltransferase to histamine clearance and brain function in mice2022
- Author(s)
  Otsuka Rina、Naganuma Fumito、Nakamura Tadaho、Miwa Hideki、Nakayama-Naono Rumi、Matsuzawa Takuro、Komatsu Yurika、Sato Yuki、Takahashi Yuna、Tatsuoka-Kitano Haruna、Yanai Kazuhiko、Yoshikawa Takeo
- Journal Title
  
  Neuropharmacology
  
  Volume: 212 Pages: 109065-109065
- DOI
  10.1016/j.neuropharm.2022.109065
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08033, KAKENHI-PROJECT-19K07828, KAKENHI-PROJECT-21K06795, KAKENHI-PROJECT-18KK0442, KAKENHI-PROJECT-23K24070
[Journal Article] Serotonin and noradrenaline modulate chronic itch processing in mice2020
- Author(s)
  Miyahara Yu、Funahashi Hideki、Naono-Nakayama Rumi、Haruta-Tsukamoto Ayaka、Muroi Chiyo、Kogoh Yoichiro、Nishimori Toshikazu、Ishida Yasushi
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 883 Pages: 173319-173319
- DOI
  10.1016/j.ejphar.2020.173319
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10277, KAKENHI-PROJECT-19K07828
[Journal Article] Pharmacological characteristics of hemokinin-1-derived peptides in rat pruriceptive processing.2020
- Author(s)
  H. Funahashi, Y. Miyahara, A.Haruta-Tsukamoto, T. Matsuo, R. Naono-Nakayama, K. Ebihara, T.Nishimori, Y. Ishida.
- Journal Title
  
  Peptides
  
  Volume: 124 Pages: 170232-170239
- DOI
  10.1016/j.peptides.2019.170232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07828, KAKENHI-PROJECT-16K08992
[Journal Article] Role of serotonin and noradrenaline in the acute itch processing in mice2019
- Author(s)
  Yu Miyahara, Hideki Funahashi, Rumi Naono-Nakayama, Ayaka Haruta-Tsukamoto, Toshikazu Nishimori, Yasushi Ishida
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 850 Pages: 118-125
- DOI
  10.1016/j.ejphar.2019.02.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08992, KAKENHI-PROJECT-17K10277
[Journal Article] Expression Analysis of Serotonin Receptors, Serotonin Transporter and l-Amino Acid Decarboxylase in the Mouse Sphenopalatine Ganglion by RT-PCR, Northern Blot Analysis and In Situ Hybridization.2019
- Author(s)
  Y. Ishida, Y. Sugiura, T. Magome, T. Kamakura, Y. Takimoto, Y.Hanada, K.Kitayama, Y. Nakamura, S. Shimada, N. Ohta, R. Naono-Nakayama, K. Kamijo
- Journal Title
  
  Neuroscience
  
  Volume: 411 Pages: 23-36
- DOI
  10.1016/j.neuroscience.2019.05.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07828, KAKENHI-PROJECT-16K08992, KAKENHI-PROJECT-18K19617
[Journal Article] 1日で結果を得る手軽な insitu hybridization ― 超微形態の確認の前に ―2018
- Author(s)
  石田雄介、直野 - 中山留美、太田伸男
- Journal Title
  
  Proc Clin Electron Microsc.
  
  Volume: 36 Pages: 5-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08992
[Journal Article] Distribution of hemokinin-1 in the rat trigeminal ganglion and2017
- Author(s)
  K. Igawa, H. Funahashi, Y. Miyahara, R. Naono-Nakayama, H. Matsuo, Y. Yamashita, S. Sakodaa, T. Nishimori,Y. Ishida
- Journal Title
  
  Archives of Oral Biology
  
  Volume: 79 Pages: 62-69
- DOI
  10.1016/j.archoralbio.2017.03.004
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16J40228, KAKENHI-PROJECT-26860384, KAKENHI-PROJECT-16K08992, KAKENHI-PROJECT-17K10277
[Journal Article] Hemokinin-1-derived peptides have antipruritic effects in rats.2015
- Author(s)
  H. Funahashi, R.Naono-Nakayama, G. Koganemaru, Y. Miyahara, T. Nishimori, K. Takamiya, Y. Ishida
- Journal Title
  
  Therapeutic Targets for Neurological Diseases
  
  Volume: 2 Pages: 1-4
- DOI
  10.14800/ttnd.704
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J07087, KAKENHI-PROJECT-24591684, KAKENHI-PROJECT-26860384, KAKENHI-PROJECT-26870451
[Journal Article] Hemokinin-1 mediates pruriceptive processing in the rat spinal cord.2014
- Author(s)
  H. Funahashi, R.Naono-Nakayama, K. Ebihara, G. Koganemaru, A. Kuramashi, T. Ikeda,T. Nishimori, Y. Ishida
- Journal Title
  
  Neuroscience
  
  Volume: 277 Pages: 206-216
- DOI
  10.1016/j.neuroscience.2014.07.001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J07087, KAKENHI-PROJECT-24591684, KAKENHI-PROJECT-26860384, KAKENHI-PROJECT-26870451
[Journal Article] New tachykinin peptides and nociception.2013
- Author(s)
  T. Nishimori, R. Naono-Nakayama, T. Ikeda
- Journal Title
  
  Japanese Dental Sci. Rev.
  
  Volume: 49 Issue: 1 Pages: 27-34
- DOI
  10.1016/j.jdsr.2012.11.002
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-13J07087, KAKENHI-PROJECT-22600008, KAKENHI-PROJECT-24790577
[Journal Article] New tachykinin peptides and nociception2012
- Author(s)
  Nishimori T, Naono-Nakayama R, Ikeda T
- Journal Title
  
  Jpn dent sci rev.
  
  Volume: 49 Pages: 27-34
- NAID
  10031201720
- URL
  http://dx.doi.org/10.1016/j.jdsr.2012.11.002
- Data Source
  KAKENHI-PROJECT-22600008
[Journal Article] Pharmacological characteristics of endokinin C/D-derived peptides in nociceptive and inflammatory processing in rats2011
- Author(s)
  Naono-Nakayama R, Sunakawa N, Ikeda T, Matsushima O, Nishimori T
- Journal Title
  
  Peptides
  
  Volume: 32 Pages: 2407-2417
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22600008
[Journal Article] Pharmacological characteristics of endokinin C/D-derived peptides in nociceptive and inflammatory processing in rats.2011
- Author(s)
  Naono-Nakayama R, Sunakawa N, Ikeda T, Matsushima O, Nishimori T
- Journal Title
  
  Peptides
  
  Volume: 32(12) Issue: 12 Pages: 2407-2417
- DOI
  10.1016/j.peptides.2011.10.009
- Data Source
  KAKENHI-PROJECT-22600008
[Journal Article] Knockdown of the tachykinin neurokinin 1 receptor by intrathecal administration of small interfering RNA in rats2011
- Author(s)
  Naono-Nakayama R, Sunakawa N, Ikeda T, Nishimori T
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 670 Pages: 448-457
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22600008
[Journal Article] Knockdown of the tachykinin neurokinin 1 receptor by intrathecal administration of small interfering RNA in rats.2011
- Author(s)
  Naono-Nakayama R, Sunakawa N, Ikeda T, Nishimori T
- Journal Title
  
  Eur J Pharmacol.
  
  Volume: 670(2-3) Issue: 2-3 Pages: 448-457
- DOI
  10.1016/j.ejphar.2011.09.035
- Data Source
  KAKENHI-PROJECT-22600008
[Journal Article] The amino-terminal region of hemokinin-1 regulates the induction of thermal hyperalgesia in rats.2010
- Author(s)
  Sunakawa N, Naono R, Ikeda T, Matsushima O, Sakoda S, Nishimori T.
- Journal Title
  
  Neuropeptides.
  
  Volume: 44 Pages: 273-278
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22600008
[Journal Article] NMDA and AMPA receptors contribute to the maintenance of substance P-induced thermal hyperalgesia.2010
- Author(s)
  Nakayama T, Naono R, Ikeda T, Nishimori T
- Journal Title
  
  Neurosci Res.
  
  Volume: 67(1) Issue: 1 Pages: 18-24
- DOI
  10.1016/j.neures.2010.01.006
- Data Source
  KAKENHI-PROJECT-22600008
[Journal Article] The amino-terminal region of hemokinin-1 regulates the induction of thermal hyperalgesia in rats.2010
- Author(s)
  Sunakawa N, Naono R, Ikeda T, Matsushima O, Sakoda S, Nishimori T
- Journal Title
  
  Neuropeptides
  
  Volume: 44(3) Issue: 3 Pages: 273-278
- DOI
  10.1016/j.npep.2010.01.003
- Data Source
  KAKENHI-PROJECT-22600008
[Journal Article] Subcutaneous injection of endokinin C/D attenuates carrageenan-induced inflammation.2010
- Author(s)
  Naono-Nakayama R, Sunakawa N, Ikeda T, Matsushima O, Nishimori T
- Journal Title
  
  Peptides
  
  Volume: 31(9) Issue: 9 Pages: 1767-1771
- DOI
  10.1016/j.peptides.2010.05.019
- Data Source
  KAKENHI-PROJECT-22600008
[Journal Article] Subcutaneous injection of endokinin C/D attenuates carrageenan-induced inflammation.2010
- Author(s)
  Naono-Nakayama R, Sunakawa N, Ikeda T, Matsushima O, Nishimori T.
- Journal Title
  
  Peptides.
  
  Volume: 31 Pages: 1767-1771
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22600008
[Journal Article] NMDA and AMPA receptors contribute to the maintenance of substance P-induced thermal hyperalgesia.2010
- Author(s)
  Nakayama T, Naono R, Ikeda T, Nishimori T.
- Journal Title
  
  Neurosci Res.
  
  Volume: 67 Pages: 18-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22600008
[Journal Article] Effect of the carboxyl-terminal of endokinins on SP-induced pain-related behavior2009
- Author(s)
  Naono R, Nakayama T, Ikeda T, Matsushima O, Nishimori T.
- Journal Title
  
  Biochem Biophys Res Commun. 378(2)(reviewed)
  
  Pages: 182-185
- Data Source
  KAKENHI-PROJECT-19603009
[Journal Article] Effect of the carboxyl-terminal of endokinins on SP-induced pain-related behavior.2009
- Author(s)
  Naono R, Nakayama T, Ikeda T, Matsushima O, Nishimori T.
- Journal Title
  
  Biochem Biophys Res Commun. 378
  
  Pages: 182-185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19603009
[Journal Article] Pharmacological characterization of desensitization in scratching behavior induced by intrathecal administration of hemokinin-1 in the rat.2008
- Author(s)
  Naono R, Nakayama T, Ikeda T, Matsushima O, Nishimori T.
- Journal Title
  
  Neuropeptides 42
  
  Pages: 47-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19603009
[Journal Article] Pharmacological characterization of desensitization in scratching behavior induced by intrathecal administration of hemokinin-1 in the rat2008
- Author(s)
  Naono R, Nakayama T, Ikeda T, Matsushima O, Nishimori T.
- Journal Title
  
  Neuropeptides 42(1)(reviewed)
  
  Pages: 47-55
- Data Source
  KAKENHI-PROJECT-19603009
[Journal Article] Leucine at the carboxyl-terminal of endokinins C and D contributes to elicitation of the antagonistic effect on substance P in rat pain processing.2007
- Author(s)
  Naono R, Nakayama T, Ikeda T, Matsushima O, Nishimori T.
- Journal Title
  
  Brain Res. 1165
  
  Pages: 71-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19603009
[Journal Article] Leucine at the carboxyl-terminal of endokinins C and D contributes to elicitation of the antagonistic effect on substance P in rat pain processing2007
- Author(s)
  Naono R, Nakayama T, Ikeda T, Matsushima O, Nishimori T.
- Journal Title
  
  Brain Res 1165(reviewed)
  
  Pages: 71-80
- Data Source
  KAKENHI-PROJECT-19603009
[Patent] GPR83の受容体機能を阻害する方法2016
- Inventor(s)
  中山留美
- Industrial Property Rights Holder
  中山留美
- Industrial Property Rights Type
  特許
- Filing Date
  2016
- Data Source
  KAKENHI-PROJECT-16K08992
[Patent] GPR83の受容体機能を阻害する方法2016
- Inventor(s)
  中山留美、髙宮考悟、西森利數
- Industrial Property Rights Holder
  中山留美、髙宮考悟、西森利數
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-112686
- Filing Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-16K08992
[Patent] ヘモキニン-１受容体及びヘモキニン-１由来ペプチド2015
- Inventor(s)
  中山留美, 西森利數
- Industrial Property Rights Holder
  中山留美, 西森利數
- Industrial Property Rights Type
  特許
- Filing Date
  2015-08-11
- Overseas
- Data Source
  KAKENHI-PROJECT-26860384
[Patent] Hemokinin-1 receptor and Hemikinin-1 derived peptide2013
- Inventor(s)
  西森利數, 中山留美
- Industrial Property Rights Holder
  西森利數, 中山留美
- Industrial Property Rights Type
  特許
- Filing Date
  2013-03-04
- Overseas
- Data Source
  KAKENHI-PROJECT-24790577
[Presentation] 疼痛および掻痒の伝達系におけるタキキニンペプチドの役割2024
- Author(s)
  中山-直野　留美, 生田　和史, 安保明博, 原田　龍一, 中村正帆, 船橋　英樹, 岡村　信行
- Organizer
  第101回　日本生理学会
- Data Source
  KAKENHI-PROJECT-19K07828
[Presentation] Role of tachykinin peptides in pruriceptive processing in mice2023
- Author(s)
  Rumi Nakayama-Naono, Akihiro Ambo, Fumito Naganuma, Tadaho Nakamura, Toshikazu Nishimori, Hideki Funahashi
- Organizer
  第100回　日本生理学会
- Data Source
  KAKENHI-PROJECT-19K07828
[Presentation] 神経ペプチドのエンドキニン類の生理学的機能2023
- Author(s)
  中山-直野留美 , 安保明博 , 船橋英樹
- Organizer
  第46回日本神経科学会
- Data Source
  KAKENHI-PROJECT-19K07828
[Presentation] 扁桃体中心核ニューロテンシン神経細胞の睡眠覚醒サイクルにおける役割の検討2023
- Author(s)
  中村正帆、長沼史登、田中聖人、井上まり絵、直野留美、吉川雄朗、岡村信行
- Organizer
  第23回応用薬理シンポジウム
- Data Source
  KAKENHI-PROJECT-19K07828
[Presentation] .炎症性疼痛におけるヒト遺伝子由来ペプチドの抑制効果2020
- Author(s)
  中山-直野留美、船橋英樹、宮原裕、石田雄介、西森利數、上条桂樹
- Organizer
  第97回　日本生理学会
- Data Source
  KAKENHI-PROJECT-16K08992
[Presentation] 炎症性疼痛におけるヒト遺伝子由来ペプチドの抑制効果2020
- Author(s)
  中山-直野留美、船橋英樹、宮原裕、石田雄介、西森利數、上条桂樹
- Organizer
  第97回　日本生理学会
- Data Source
  KAKENHI-PROJECT-19K07828
[Presentation] ヒト遺伝子由来ペプチドエンドキニンC/Dは、痛みと炎症の抑制効果を有する2019
- Author(s)
  中山-直野留美、船橋英樹、宮原裕、石田雄介、西森利數、上条桂樹
- Organizer
  第42回日本神経科学会
- Data Source
  KAKENHI-PROJECT-16K08992
[Presentation] ヒト遺伝子由来ペプチドエンドキニンC/Dは、痛みと炎症の抑制効果を有する2019
- Author(s)
  中山-直野留美、船橋英樹、宮原裕、石田雄介、西森利數、上条桂樹
- Organizer
  第42回日本神経科学会
- Data Source
  KAKENHI-PROJECT-19K07828
[Presentation] Hemokinin-1 (1-5) elicits the inhibitory effect on pruritic processing in the rat spinal cord2018
- Author(s)
  中山-直野　留美、船橋　英樹、宮原　裕、西森　利數
- Organizer
  第95回　日本生理学会
- Data Source
  KAKENHI-PROJECT-16K08992
[Presentation] Hemokinin-1　contribute to itch processing in the spinal cord2018
- Author(s)
  Rumi Naono-Nakayma, Hideki Funahashi, Yu Miyahara, Yusuke Ishida, Toshikazu Nishimori, Keiju Kamijyo
- Organizer
  第41回　日本神経科学会
- Data Source
  KAKENHI-PROJECT-16K08992
[Presentation] サブスタンスP受容体に類似する受容体の脊髄における役割2017
- Author(s)
  中山(直野) 留美、石田雄介、船橋英樹、宮原 2、髙宮考悟、西森利數、上条桂樹
- Organizer
  第63回　東北・北海道連合支部　学術集会
- Data Source
  KAKENHI-PROJECT-16K08992
[Presentation] New tachykinin receptor mediates pruricepitive pricessing in the spinal cord2016
- Author(s)
  R. Nakayama-Naono, H. Funahashi, Y. Miyahara, T. Nishimori, K. Takamiya
- Organizer
  第16回　国際疼痛学会
- Place of Presentation
  パシフィコ横浜(神奈川県・横浜市)
- Year and Date
  2016-09-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860384
[Presentation] New tachykinin receptor mediates pruriceptive processing in the spinal cord2016
- Author(s)
  R. Nakayama-Naono, H. Funahashi, Y. Miyahara, T. Nishimori, K. Takamiya
- Organizer
  第１６回　国際疼痛学会
- Place of Presentation
  パシフィコ横浜(神奈川県・横浜市)
- Year and Date
  2016-09-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08992
[Presentation] New tachykinin receptor mediates pruriceptive processing in the spinal cord2016
- Author(s)
  R. Naono-Nakayama
- Organizer
  The 3rd International Symposium on Glyco-Neuroscience
- Place of Presentation
  兵庫県、淡路島
- Year and Date
  2016-01-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860384
[Presentation] ヘモキニンー１フラグメントペプチドHK-1(1-5)が痒み伝達を抑制する2015
- Author(s)
  中山-直野　留美、船橋　英樹、西森　利數、髙宮　考悟
- Organizer
  第37回　日本疼痛学会
- Place of Presentation
  熊本県、熊本市
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-26860384
[Presentation] Orphan receptor GPR83 mediates pruriceptive processing in the spinal cord2015
- Author(s)
  R. Naono-Nakayama, H. Funahashi,, K. Takamiya, T. Nishimori.
- Organizer
  8th World congress on itch
- Place of Presentation
  奈良県、奈良市
- Year and Date
  2015-09-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860384
[Presentation] Effect of a fragment peptide derived from hemokinin-1 on histamine- or serotonin-induced scratching2012
- Author(s)
  Naono-Nakayama R, Ikeda T, Takamiya K, Sameshima H, Nishimori T
- Organizer
  Society for Neuroscience, 42th Annual Meeting
- Place of Presentation
  New Orleans, USA.
- Data Source
  KAKENHI-PROJECT-22600008
[Presentation] Effect of a fragment peptide derived from hemokinin-1 on histamine or serotonin-induced scratching.2012
- Author(s)
  R. Naono-Nakayama
- Organizer
  Society for Neuroscience 2012
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-24790577
[Presentation] Effect of a fragment peptide derived from hemokinin-1 on histamine- or serotonin-induced scratching.2012
- Author(s)
  Naono-Nakayama R, Ikeda T, Takamiya K, Sameshima H, Nishimori T.
- Organizer
  Society for Neuroscience, 42th Annual Meeting
- Place of Presentation
  New Orleans
- Data Source
  KAKENHI-PROJECT-22600008
[Presentation] 疼痛およびかゆみに対するヘモキニン-1由来フラグメントペプチドの効果2011
- Author(s)
  中山-直野留美, 池田哲也, 西森利數
- Organizer
  第34回日本神経科学学会
- Place of Presentation
  横浜
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-22600008
[Presentation] 疼痛およびかゆみに対するヘモキニン-1由来フラグメントペプチドの効果.2011
- Author(s)
  中山-直野留美, 池田哲也, 西森利數
- Organizer
  第34回日本神経科学学会
- Place of Presentation
  横浜
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-22600008
[Presentation] siRNAのラット髄腔内投与によるNK1受容体のノックダウン.2008
- Author(s)
  直野留美, 砂川奈津季, 池田哲也, 西森利數.
- Organizer
  第30回日本疼痛学会
- Place of Presentation
  福岡
- Year and Date
  2008-07-20
- Data Source
  KAKENHI-PROJECT-19603009
[Presentation] Effects of neurokinin 1 receptor knock-down by intrathecal administration of siRNA on pain processing in rats.2008
- Author(s)
  Naono R, Sunakawa N, Ikeda T, Nishimori T.
- Organizer
  Society for Neuroscience, 38th Annual Meeting
- Place of Presentation
  Washington DC
- Year and Date
  2008-11-19
- Data Source
  KAKENHI-PROJECT-19603009
[Presentation] Phosphorylation mediated by NK1 receptor sensitizes a TRPV1 channel and desensitizes TRPA1 and TRPM8 channels in rats2008
- Author(s)
  Naono R, Sunakawa N, Ikeda T, Nishimori T.
- Organizer
  第31回日本神経科学会
- Place of Presentation
  東京
- Year and Date
  2008-07-09
- Data Source
  KAKENHI-PROJECT-19603009
[Presentation] Functional interaction between the Neurokinin-1 receptor and TRP channels (TRPV1, TRPA1 and TRPM8) in the rat spinal cord2008
- Author(s)
  Naono R, Sunakawa N, Ikeda T, Nishimori T.
- Organizer
  International Association of the Study of Pain
- Place of Presentation
  Glasgow
- Year and Date
  2008-08-19
- Data Source
  KAKENHI-PROJECT-19603009
[Presentation] Effects of neurokinin 1 receptor knock-down by intrathecal administration of siRNA on pain processing in rats2008
- Author(s)
  Naono R, Sunakawa N, Ikeda T, Nishimori T.
- Organizer
  Society for Neuroscience, 38th Annual Meeting
- Place of Presentation
  Washington DC.
- Year and Date
  2008-11-19
- Data Source
  KAKENHI-PROJECT-19603009
[Presentation] Functional interaction between the Neurokinin-l receptor and TRP channels (TRPV1, TRPA1 and TRPM8) in the rat spinal cord.2008
- Author(s)
  Naono R, Sunakawa N, Ikeda T, Nishimori T.
- Organizer
  International Association of the Study of Pain
- Place of Presentation
  英国 Glasgow
- Year and Date
  2008-08-19
- Data Source
  KAKENHI-PROJECT-19603009
[Presentation] NMDA・AMPA誘発痛覚過敏にNK1 receptorとmGluR1, 5が関与する2008
- Author(s)
  砂川奈津季, 直野留美, 池田哲也, 西森利數
- Organizer
  第30回日本疼痛学会
- Place of Presentation
  福岡
- Year and Date
  2008-07-20
- Data Source
  KAKENHI-PROJECT-19603009
[Presentation] Phosphorylation mediated by NK1 receptor sensitizes a TRPV1 channel and desensitizes TRPA1 and TRPM8 channels in rats.2008
- Author(s)
  Naono R, Sunakawa N, Ikeda T, Nishimori T.
- Organizer
  第31回日本神経科学会
- Place of Presentation
  東京
- Year and Date
  2008-07-09
- Data Source
  KAKENHI-PROJECT-19603009
[Presentation] NMDA・AMPA 誘発痛覚過敏にNK1 receptorとmGluR1, 5が関与する.2008
- Author(s)
  砂川奈津季, 直野留美, 池田哲也, 西森利數.
- Organizer
  第30回日本疼痛学会
- Place of Presentation
  福岡
- Year and Date
  2008-07-20
- Data Source
  KAKENHI-PROJECT-19603009
[Presentation] siRNAのラット髄腔内投与によるNK1受容体のノックダウン2008
- Author(s)
  直野留美, 砂川奈津季, 池田哲也, 西森利數
- Organizer
  第30回日本疼痛学会
- Place of Presentation
  福岡
- Year and Date
  2008-07-20
- Data Source
  KAKENHI-PROJECT-19603009
[Presentation] ヘモキニン-1誘発desensitizationの特徴2007
- Author(s)
  直野留美, 池田哲也, 西森利數
- Organizer
  第29回日本疼痛学会
- Place of Presentation
  横浜
- Year and Date
  2007-07-07
- Data Source
  KAKENHI-PROJECT-19603009
[Presentation] ヘモキニン-1誘発desensitizationの特徴.2007
- Author(s)
  直野留美, 池田哲也, 西森利数.
- Organizer
  第29回日本疼痛学会
- Place of Presentation
  横浜市
- Year and Date
  2007-07-07
- Data Source
  KAKENHI-PROJECT-19603009
[Presentation] Hemokinin-1 (1-5) elicits the inhibitory effect on pruritic processing.
- Author(s)
  R. Naono-Nakayama, H. Funahashi,, K. Takamiya, T. Nishimori.
- Organizer
  Society for Neuroscience 2014
- Place of Presentation
  ワシントン(米国)
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-26860384
[Presentation] An amino-terminal fragment of Hemokinin-1 has an inhibitory effect on pruritic processing in rats.
- Author(s)
  R. Naono-Nakayama, H. Funahashi,, K. Takamiya, T. Nishimori.
- Organizer
  第 37 回日本神経科学会
- Place of Presentation
  パシフィコ横浜(神奈川県・横浜市)
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-26860384

1. IKEDA Tetsuya (20264369)

# of Collaborated Projects: 3 results

# of Collaborated Products: 33 results
2. NISHIMORI Toshikazu (20112211)

# of Collaborated Projects: 2 results

# of Collaborated Products: 34 results
3. 北村大志 (20706949)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 生田和史 (60512184)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MIWA Hideki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 石田康

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakayama Rumi 中山 留美 (直野 留美)

Nakayama-Naono Rumi 中山 留美

直野留美

中山 留美(直野留美) ナカヤマ ルミ

NAKAYAMA Rumi 中山 留美

NAONO Rumi 直野 留美

Research Projects

Research Products

Co-Researchers

Evaluation of novel biomarkers using peptides in pruritic processingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of GPR83 and related molecules for antipruritus drugsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional association with GPR83 and other itch receptors in the spinal cordPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

New tachykinin receptor mediates pruriceptive processing in the spinal cordPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヘモキニン－１由来ペプチドの疼痛および掻痒治療薬の開発に関する基礎的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on structure and function of novel tachykinin peptides

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the contribution of novel tachykinin peptides to the pain system

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 痒み伝達におけるタキキニンペプチドの役割2023

Author(s)

Journal Title

Data Source

[Journal Article] Contribution of astrocytic histamine N-methyltransferase to histamine clearance and brain function in mice2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Serotonin and noradrenaline modulate chronic itch processing in mice2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pharmacological characteristics of hemokinin-1-derived peptides in rat pruriceptive processing.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of serotonin and noradrenaline in the acute itch processing in mice2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression Analysis of Serotonin Receptors, Serotonin Transporter and l-Amino Acid Decarboxylase in the Mouse Sphenopalatine Ganglion by RT-PCR, Northern Blot Analysis and In Situ Hybridization.2019

Author(s)

Journal Title

DOI

Data Source

Nakayama Rumi 中山留美 (直野留美)

Nakayama-Naono Rumi 中山留美

中山留美(直野留美) ナカヤマルミ

NAKAYAMA Rumi 中山留美

NAONO Rumi 直野留美