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Kakizaki Fumihiko  柿崎 文彦

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Fumihiko Kakizaki  柿崎 文彦

KAKIZAKI Fumihiko  柿崎 文彦

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Researcher Number 00609076
Other IDs
Affiliation (Current) 2025: 京都大学, 医学研究科, 助教
Affiliation (based on the past Project Information) *help 2021 – 2024: 京都大学, 医学研究科, 助教
2015: 京都大学, 大学院医学研究科, 特定研究員
2013 – 2015: 京都大学, 医学(系)研究科(研究院), 研究員
Review Section/Research Field
Principal Investigator
Basic Section 49030:Experimental pathology-related
Except Principal Investigator
Pathological medical chemistry
Keywords
Principal Investigator
マウスモデル / がん転移 / 予後不良 / がん幹細胞 / トランスクリプトーム / 転移 / 大腸がん / TRIO
Except Principal Investigator
がん転移 / 予後診断 … More / TGF-betaシグナル / Notchシグナル / ケモカイン / 消化器 / がん / TRIO / ABL / NOTCH / AES / 予後マーカー / 転移 / 浸潤 / 消化器がん Less
  • Research Projects

    (3 results)
  • Research Products

    (13 results)
  • Co-Researchers

    (7 People)
  •  Studies on mechanisms of metastasis in colorectal cancer stem cell subtypes using mouse models and clinical materialsPrincipal Investigator

    • Principal Investigator
      柿崎 文彦
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Kyoto University
  •  Studies on metastasis of colorectal cancer stem cells using clinical materials and mouse modelsPrincipal Investigator

    • Principal Investigator
      Fumihiko Kakizaki
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Kyoto University
  •  Studies on digestive system cancer metastasis using mouse models

    • Principal Investigator
      TAKETO Makoto
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kyoto University

All 2024 2023 2022 2017 2016 2015 2013

All Journal Article Presentation Patent

  • [Journal Article] Novel and efficient method for culturing patient‐derived gastric cancer stem cells2023

    • Author(s)
      Morimoto Tomonori、Takemura Yukitoshi、Miura Takemitsu、Yamamoto Takehito、Kakizaki Fumihiko、An Hideo、Maekawa Hisatsugu、Yamaura Tadayoshi、Kawada Kenji、Sakai Yoshiharu、Yuba Yoshiaki、Terajima Hiroaki、Obama Kazutaka、Taketo Makoto Mark、Miyoshi Hiroyuki
    • Journal Title

      Cancer Science

      Volume: 114 Issue: 8 Pages: 3259-3269

    • DOI

      10.1111/cas.15840

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07187, KAKENHI-PROJECT-21K06948, KAKENHI-PROJECT-18H02639
  • [Journal Article] Efficacious Combination Drug Treatment for Colorectal Cancer that Overcomes Resistance to KRAS G12C Inhibitors2023

    • Author(s)
      Matsubara Hiroyuki、Miyoshi Hiroyuki、Kakizaki Fumihiko、Morimoto Tomonori、Kawada Kenji、Yamamoto Takehito、Obama Kazutaka、Sakai Yoshiharu、Taketo Makoto Mark
    • Journal Title

      Molecular Cancer Therapeutics

      Volume: 22 Issue: 4 Pages: 529-538

    • DOI

      10.1158/1535-7163.mct-22-0411

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06948, KAKENHI-PROJECT-18H02639
  • [Journal Article] Expression of metastasis suppressor gene AES driven by a Yin Yang (YY) element in a CpG island promoter and transcription factor YY22016

    • Author(s)
      Kakizaki F, Sanoshita M, Miyoshi H, Itatani Y, Ito S, Kawada K, Sakai Y and Taketo MM
    • Journal Title

      Cancer Science

      Volume: 107 Issue: 11 Pages: 1622-1631

    • DOI

      10.1111/cas.13063

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25253022
  • [Journal Article] Promotion of Colorectal Cancer Invasion and Metastasis Through Activation of Notch-Dab1-Abl-RhoGEF Protein Trio.2015

    • Author(s)
      Sonoshita M, Itatani Y, Kakizaki F, Sakimura K, Terashima T, Katsuyama Y, Sakai Y, Taketo MM.
    • Journal Title

      Cancer Discov.

      Volume: 5 Issue: 2 Pages: 198-211

    • DOI

      10.1158/2159-8290.cd-14-0595

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24300126, KAKENHI-PROJECT-24650177, KAKENHI-PROJECT-26440112, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-25253022
  • [Journal Article] Characterization of Aes nuclear foci in colorectal cancer cells2015

    • Author(s)
      Yoshiro Itatani1,2, Masahiro Sonoshita1, Fumihiko Kakizaki1, Katsuya Okawa3, Stefano Stifani4, Hideaki Itoh5, Yoshiharu Sakai2 and M. Mark Taketo1,2,*
    • Journal Title

      J. Biochem.

      Volume: 159 Issue: 1 Pages: 133-140

    • DOI

      10.1093/jb/mvv077

    • NAID

      40020725723

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25253022
  • [Journal Article] Loss of SMAD4 from colorectal cancer cells promotes CCL15 expression to recruit CCR1+ myeloid cells and facilitate liver metastasis.2013

    • Author(s)
      Itatani Y, Kawada K, Fujishita T, Kakizaki F, Hirai H, Matsumoto T, Iwamoto M, Inamoto S, Hatano E, Hasegawa S, Maekawa T, Uemoto S, Sakai Y, Taketo MM
    • Journal Title

      Gastroenterol

      Volume: 145(5) Issue: 5 Pages: 1064-1075

    • DOI

      10.1053/j.gastro.2013.07.033

    • NAID

      120005348333

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390244, KAKENHI-PROJECT-24591975, KAKENHI-PROJECT-24659461, KAKENHI-PROJECT-24790382, KAKENHI-PUBLICLY-25112706, KAKENHI-PROJECT-25253022, KAKENHI-PROJECT-25430149, KAKENHI-PROJECT-25461415
  • [Patent] 大腸がん患者の予後予測方法(再出願)2024

    • Inventor(s)
      武藤誠、柿崎文彦、三好弘之、河田健二、小濵和貴
    • Industrial Property Rights Holder
      国立大学法人京都大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2024
    • Data Source
      KAKENHI-PROJECT-21K06948
  • [Patent] 「大腸がん患者の予後予測方法」2022

    • Inventor(s)
      武藤誠、柿崎文彦、三好弘之、河田健二、小濵和貴
    • Industrial Property Rights Holder
      武藤誠、柿崎文彦、三好弘之、河田健二、小濵和貴
    • Industrial Property Rights Type
      特許
    • Filing Date
      2022
    • Data Source
      KAKENHI-PROJECT-21K06948
  • [Presentation] New horizons of precision medicine opened by colorectal cancer stem cell spheroids2023

    • Author(s)
      Taketo MM, Miyoshi H, Kakizaki F, Yamaura T, Maekawa H, Yamamoto T, Kitano S, Matsubara H, Morimoto T, Kawada K, Obama K, Sakai Y.
    • Organizer
      The 2nd JCA-AACR Precision Cancer Medicine International Conference
    • Data Source
      KAKENHI-PROJECT-21K06948
  • [Presentation] Expression of metastasis suppressor gene AES driven by a Yin Yang (YY) element in a CpG island promoter and transcription factor YY22017

    • Author(s)
      柿崎 文彦
    • Organizer
      日本癌学会学術総会 Cancer Science Young Scientist Award
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2017-09-28
    • Data Source
      KAKENHI-PROJECT-25253022
  • [Presentation] Promotion of Colorectal Cancer Invasion and Metastasis through Activation of Notch-Dab1-Abl-RhoGEF Protein Trio2015

    • Author(s)
      Masahiro Sonoshita1 , Yoshiro Itatani1,2 , Fumihiko Kakizaki1 and Yoshiharu Sakai2, M. Mark Taketo1,2
    • Organizer
      AACR Tumor Metastasis Meeting
    • Place of Presentation
      Austin, TX, USA
    • Year and Date
      2015-11-30
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25253022
  • [Presentation] CCL15-CCR1 axisによる大腸癌肝転移機序と、CCR1阻害薬による肝転移抑制への期待2013

    • Author(s)
      板谷喜朗、河田健二、藤下晃章、柿崎文彦、平位秀世、松本卓也、波多野悦朗、坂井義治,上本伸二、武藤誠
    • Organizer
      第113回日本外科学会定期学術集会
    • Place of Presentation
      福岡市
    • Data Source
      KAKENHI-PROJECT-25253022
  • [Presentation] Loss of Smad4 in Colorectal Cancer Cells Promotes CCL15 Expression to Recruit CCR1+ Myeloid Cells and Facilitate Liver Metastasis.2013

    • Author(s)
      Yoshiro Itatani,Kawada K, Fujishita T, Kakizaki F, Hirai H, Matsumoto T, Iwamoto M, Inamoto S, Hatano E, Hasegawa S, Maekawa T, Uemoto S, Sakai Y, Taketo MM
    • Organizer
      American College of Surgeons
    • Place of Presentation
      Washington, DC, USA
    • Data Source
      KAKENHI-PROJECT-25253022
  • 1.  TAKETO Makoto (70281714)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 8 results
  • 2.  SONOSHITA Masahiro (80511857)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 3.  伊藤 慎二 (50362512)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  寺島 俊雄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  三好 弘之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  前川 平
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  平位 秀世
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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