Sakata Seiji 坂田征士

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SAKATA Seiji 坂田征士

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Researcher Number	00617433
Affiliation (Current)	2025: 公益財団法人がん研究会, がん研究所病理部, 研究員
Affiliation (based on the past Project Information) *help	2016 – 2022: 公益財団法人がん研究会, がん研究所分子標的病理プロジェクト, 研究員 2014 – 2015: 公益財団法人がん研究会, 分子標的病理プロジェクト, 研究員 2013: 公益財団法人がん研究会, がん研究所分子標的病理プロジェクト, 研究員
Review Section/Research Field	Principal Investigator Tumor diagnostics / Basic Section 49020:Human pathology-related / Experimental pathology
Keywords	Principal Investigator バイオマーカー / 融合遺伝子 / チロシンキナーゼ / 構造異常 / 免疫チェックポイント分子

Molecular pathology evaluation method of PD-L1/PD-L2 focusing on structural and splicing abnormalitiesPrincipal Investigator
- Principal Investigator
  
  SAKATA Seiji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Japanese Foundation for Cancer Research
Identification of genomic structural variations leading to high expression of immune checkpoint molecules in cancer cells and establishment of detection methodPrincipal Investigator
- Principal Investigator
  
  Sakata Seiji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Japanese Foundation for Cancer Research
Identificaition of novel tyrosine kinase fusion genes in gynecological tumorsPrincipal Investigator
- Principal Investigator
  
  SAKATA Seiji
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Japanese Foundation for Cancer Research
Identification of novel tyrosine kinase fusion genes in colorectal cancerPrincipal Investigator
- Principal Investigator
  
  SAKATA Seiji
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Japanese Foundation for Cancer Research

All 2023 2022 2021 2019 2014

All Journal Article Presentation Patent

[Journal Article] Soluble PD-L1 works as a decoy in lung cancer immunotherapy via alternative polyadenylation2022
- Author(s)
  Sagawa Ray、Sakata Seiji、Gong Bo、Seto Yosuke、Takemoto Ai、Takagi Satoshi、Ninomiya Hironori、Yanagitani Noriko、Nakao Masayuki、Mun Mingyon、Uchibori Ken、Nishio Makoto、Miyazaki Yasunari、Shiraishi Yuichi、Ogawa Seishi、Kataoka Keisuke、Fujita Naoya、Takeuchi Kengo、Katayama Ryohei
- Journal Title
  
  JCI Insight
  
  Volume: 7 Issue: 1 Pages: 1-19
- DOI
  10.1172/jci.insight.153323
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21554, KAKENHI-PROJECT-20K16370, KAKENHI-PLANNED-17H06327, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-19H03524, KAKENHI-PROJECT-20K07399
[Journal Article] Epigenetic silencing by SMYD3 represses tumor intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck2022
- Author(s)
  Nigam N、Bernard B、Kim S、Burkitt K、Tsai D、Robbins Y、Sievers C、Clint A、Bennett RL、Tettey TT、Carter B、Bao R、Rinaldi L、Lingen M.W.、Sater H、Edmondson EF、Cheng H、Luo X、Brennan K、Chen C、Sevilla S、Murali M、Sakata S、Takeuchi K、Nakamura Y、Uppaluri R、Sunwoo JB、Van Waes C、Licht JD、Hager GL、Saloura V
- Journal Title
  
  cell reports
  
  Volume: -
- DOI
  10.1101/2022.11.04.515098
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07399
[Journal Article] Secreted PD-L1 variants mediate resistance to PD-L1 blockade therapy in non-small cell lung cancer2019
- Author(s)
  Gong Bo, Kiyotani Kazuma, Sakata Seiji, Nagano Seiji, Kumehara Shun, Baba Satoko, Besse Benjamin, Yanagitani Noriko, Friboulet Luc, Nishio Makoto, Takeuchi Kengo, Kawamoto Hiroshi, Fujita Naoya, Katayama Ryohei
- Journal Title
  
  The Journal of Experimental Medicine
  
  Volume: 216 Issue: 4 Pages: 982-1000
- DOI
  10.1084/jem.20180870
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07205, KAKENHI-PROJECT-16H04715, KAKENHI-PROJECT-16H06276, KAKENHI-ORGANIZER-17H06324, KAKENHI-PLANNED-17H06327, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-18K19485
[Journal Article] Frequent structural variations involving programmed death ligands in Epstein-Barr virus-associated lymphomas2019
- Author(s)
  Kataoka Keisuke, Miyoshi Hiroaki, Sakata Seiji, Dobashi Akito, Couronne Lucile, Kogure Yasunori, Sato Yasuharu, Nishida Kenji, Gion Yuka, Shiraishi Yuichi, Tanaka Hiroko, et al
- Journal Title
  
  Leukemia
  
  Volume: Epub ahead of print Issue: 7 Pages: 1687-1699
- DOI
  10.1038/s41375-019-0380-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07205, KAKENHI-PROJECT-17K10136, KAKENHI-PLANNED-15H05909, KAKENHI-PLANNED-15H05912, KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-16H05338, KAKENHI-PROJECT-19K09232, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-19H01053, KAKENHI-PROJECT-17K18335
[Journal Article] 上皮性腫瘍における融合遺伝子2014
- Author(s)
  竹内賢吾、坂田征士（共同執筆）
- Journal Title
  
  実験医学
  
  Volume: 32 Pages: 1948-1954
- Data Source
  KAKENHI-PROJECT-25871072
[Patent] XX融合体の検出法2014
- Inventor(s)
  竹内賢吾、冨樫由紀、坂田征士、馬場響子
- Industrial Property Rights Holder
  がん研究会
- Industrial Property Rights Type
  特許
- Filing Date
  2014-07-25
- Overseas
- Data Source
  KAKENHI-PROJECT-25871072
[Patent] 新規融合体及びその検出法(ZZ)2014
- Inventor(s)
  竹内賢吾、朝賀礼美、坂田征士、藤田直也、片山量平
- Industrial Property Rights Holder
  がん研究会
- Industrial Property Rights Type
  特許
- Filing Date
  2014-10-29
- Overseas
- Data Source
  KAKENHI-PROJECT-25871072
[Patent] 新規融合体及びその検出法(YY)2014
- Inventor(s)
  竹内賢吾、冨樫由紀、坂田征士、藤田直也、片山量平
- Industrial Property Rights Holder
  がん研究会
- Industrial Property Rights Type
  特許
- Filing Date
  2014-10-29
- Overseas
- Data Source
  KAKENHI-PROJECT-25871072
[Presentation] MET amplification in head and neck cancer: the frequency and predictive value for immune checkpoint inhibitor therapy2023
- Author(s)
  Kenji Nakano, Seiji Sakata, Yasuyoshi Sato, Xiaofei Wang, Naomi Hayashi, Hirotaka Suto, Ryosuke Oki, Naoki Fukuda, Tetsuya Urasaki, Makiko Ono, Junichi Tomomatsu, Hiroki Mitani and Shunji Takahashi
- Organizer
  日本臨床腫瘍学会
- Data Source
  KAKENHI-PROJECT-20K07399
[Presentation] ニボルマブ療法におけるPD-L1発現および好中球／リンパ球比（NRL）のバイオマーカーとしての有用性2021
- Author(s)
  佐藤靖祥、坂田征士、佐藤由紀子、福田直樹、王暁斐、浦崎哲也、大本晃弘、林直美、仲野兼司、小野麻紀子、友松純一、三谷浩樹、高橋俊二
- Organizer
  頭頚部癌学会
- Data Source
  KAKENHI-PROJECT-20K07399

1. RYOUHEI Katayama

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sakata Seiji 坂田 征士

SAKATA Seiji 坂田 征士

Research Projects

Research Products

Co-Researchers

Molecular pathology evaluation method of PD-L1/PD-L2 focusing on structural and splicing abnormalitiesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of genomic structural variations leading to high expression of immune checkpoint molecules in cancer cells and establishment of detection methodPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identificaition of novel tyrosine kinase fusion genes in gynecological tumorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of novel tyrosine kinase fusion genes in colorectal cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Soluble PD-L1 works as a decoy in lung cancer immunotherapy via alternative polyadenylation2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Epigenetic silencing by SMYD3 represses tumor intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Secreted PD-L1 variants mediate resistance to PD-L1 blockade therapy in non-small cell lung cancer2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Frequent structural variations involving programmed death ligands in Epstein-Barr virus-associated lymphomas2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 上皮性腫瘍における融合遺伝子2014

Author(s)

Journal Title

Data Source

[Patent] XX融合体の検出法2014

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Patent] 新規融合体及びその検出法(ZZ)2014

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Patent] 新規融合体及びその検出法(YY)2014

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Presentation] MET amplification in head and neck cancer: the frequency and predictive value for immune checkpoint inhibitor therapy2023

Author(s)

Organizer

Data Source

[Presentation] ニボルマブ療法におけるPD-L1発現および好中球／リンパ球比（NRL）のバイオマーカーとしての有用性2021

Author(s)

Organizer

Data Source

Sakata Seiji 坂田征士

SAKATA Seiji 坂田征士