Asaka Ryoichi 浅香亮一

… Alternative Names

ASAKA Ryoichi 浅香亮一

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Researcher Number	00623688
Other IDs	https://orcid.org/0000-0003-4450-5142
Affiliation (Current)	2025: 信州大学, 学術研究院医学系(医学部附属病院), 助教
Affiliation (based on the past Project Information) *help	2021 – 2024: 信州大学, 学術研究院医学系(医学部附属病院), 助教 2016 – 2018: 信州大学, 学術研究院医学系(医学部附属病院), 助教 2015: 信州大学, 医学部附属病院, 助教(特定雇用) 2015: 信州大学, 医学部附属病院, 助教 2014: 信州大学, 医学部附属病院, 助教(診療) 2012 – 2013: 信州大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology Except Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology
Keywords	Principal Investigator 卵巣癌 / SIRT1 / 子宮内膜癌 / Sirtuin1 / 子宮頸部腺癌 / TAZ / YAP / 婦人科癌 / 婦人科悪性腫瘍 / 分子標的薬 … More / シスプラチン / 酸化ストレス耐性 / SIRT1阻害薬 / 癌幹細胞 / 抗がん剤耐性 / サーチュイン / 増殖能 / p53 / 脱アセチル化 / 長寿遺伝子 / EX527 / SIRT1阻害剤 / シスプラチン耐性 … More Except Principal Investigator 子宮体癌 / 低分子化合物 / 分子標的薬 / サイクリンA / 子宮内膜癌 / 妊娠高血圧腎症 / 栄養膜細胞 / 抗酸化酵素 / NRF2 / アジスロマイシン / マクロライド / 酸化ストレス耐性 / トロホブラスト / マウスモデル / オルガノイド / 子宮頸部胃型腺癌 / cisplatin / AITC / apoptosis / NK cell activity / endometrial carcinoma / NK細胞活性 / Wasabi / ナチュラルキラー細胞 / アポトーシス / 天然化合物 / ワサビ / イソチオシアネート / 6-MITC / 子宮体がん / 抗癌剤感受性 / 抗腫瘍薬 / 創薬 / 婦人科腫瘍学 / 抗がん剤 / 化合物X / 細胞周期調節因子 / prohibitin Less

Development of an experimental model of gastric-type adenocarcinoma of the uterine cervix and its drug sensitivity
- Principal Investigator
  
  井田耕一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Shinshu University
YAP/TAZを標的とした子宮頸部胃型腺癌の新規治療法の検討Principal Investigator
- Principal Investigator
  
  浅香亮一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Shinshu University
Investigation of the effects of macrolide antimicrobial agents on oxidative stress tolerance in trophoblast cells
- Principal Investigator
  
  安藤大史
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Shinshu University
Research of antitumor effects of 6-MITC, a natural compound derived from wasabi, on endometrial cancer
- Principal Investigator
  
  Fuseya Chiho
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Shinshu University
The efficacy of novel ovarian cancer treatment targeting SIRT1Principal Investigator
- Principal Investigator
  
  Asaka Ryoichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Shinshu University
Development of novel anti-cancer drugs targeting cyclin A for endometrial carcinoma.
- Principal Investigator
  
  Shiozawa Tanri
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Shinshu University
Investigation of SIRT1-function and the effect of SIRT1 inhibitor in endometrial cancerPrincipal Investigator
- Principal Investigator
  
  Asaka Ryoichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Shinshu University
Development of a new drug for endometrial carcinoma targeting cycylin A
- Principal Investigator
  
  SHIOZAWA Tanri
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Shinshu University
Analysis of the expression and function of SIRT1 in endometrial carcinomaPrincipal Investigator
- Principal Investigator
  
  ASAKA Ryoichi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Shinshu University

All 2023 2022 2021 2017 2016 2015 2013 2012 Other

All Journal Article Presentation

[Journal Article] Anti-tumor effect of Wasabi component, 6-(methylsulfinyl) hexyl isothiocyanate, against endometrial carcinoma cells2023
- Author(s)
  Ono Motoki、Miyamoto Tsutomu、Fuseya Chiho、Asaka Ryoichi、Ando Hirofumi、Tanaka Yasuhiro、Shinagawa Manaka、Yokokawa Yusuke、Takeuchi Hodaka、Horiuchi Akiko、Shiozawa Tanri
- Journal Title
  
  Discover Oncology
  
  Volume: 14 Issue: 1 Pages: 9-9
- DOI
  10.1007/s12672-023-00617-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09537
[Journal Article] Elevated Serum Levels of Estradiol Induce Endometrial Hyperplasia Rather than Carcinoma in a Mouse Model Using a Carcinogen2017
- Author(s)
  Asaka Ryoichi、Miyamoto Tsutomu、Yamada Yasushi、Ando Hirofumi、Mvunta David Hamisi、Kobara Hisanori、Kashima Hiroyasu、Shiozawa Tanri
- Journal Title
  
  Journal of Carcinogenesis & Mutagenesis
  
  Volume: 08 Issue: 06 Pages: 1-6
- DOI
  10.4172/2157-2518.1000308
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10711
[Journal Article] SIRT1 Regulates the Chemoresistance and Invasiveness of Ovarian Carcinoma Cells2017
- Author(s)
  Mvunta David Hamisi、Miyamoto Tsutomu、Asaka Ryoichi、Yamada Yasushi、Ando Hirofumi、Higuchi Shotaro、Ida Koichi、Kashima Hiroyasu、Shiozawa Tanri
- Journal Title
  
  Translational Oncology
  
  Volume: 10 Issue: 4 Pages: 621-631
- DOI
  10.1016/j.tranon.2017.05.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10711
[Journal Article] Overexpression of SIRT1 is Associated With Poor Outcomes in Patients With Ovarian Carcinoma.2016
- Author(s)
  Mvunta DH, Miyamoto T, Asaka R, Yamada Y, Ando H, Higuchi S, Ida K, Kashima H, Shiozawa T.
- Journal Title
  
  Applied Immunohistchemistry ＆ Molecular Morphology
  
  Volume: - Issue: 6 Pages: 415-421
- DOI
  10.1097/pai.0000000000000316
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10711
[Journal Article] Sirtuin 1 promotes the growth and cisplatin resistance of endometrial carcinoma cells: a novel therapeutic target.2015
- Author(s)
  Asaka R, Miyamoto T, Yamada Y, Ando H, Mvunta DH, Kobara H, Shiozawa T
- Journal Title
  
  Lab Invest
  
  Volume: 95 Issue: 12 Pages: 1363-73
- DOI
  10.1038/labinvest.2015.119
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10710, KAKENHI-PROJECT-15K10711, KAKENHI-PROJECT-15K10712, KAKENHI-PROJECT-25293339
[Journal Article] Immunohistochemical expression of core 2 β1, 6-N-acetylglucosaminyl transferase 1 (C2GnT1) in endometrioid-type endometrial carcinoma : a novel potential prognostic factor2013
- Author(s)
  Miyamoto T, Suzuki A, Asaka R, Ishikawa K, Yamada Y, Kobara H, Nakayama J, Shiozawa T
- Journal Title
  
  Histopathology
  
  Volume: 62 Pages: 986-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791696
[Journal Article] Immunohistochemical expression of core 2 β1,6-N-acetylglucosaminyl transferase 1 (C2GnT1) in endometrioid-type endometrial carcinoma: a novel potential prognostic factor.2013
- Author(s)
  Miyamoto T
- Journal Title
  
  Histopathology
  
  Volume: Feb 9 [Epub ahead of print] Issue: 7 Pages: 986-93
- DOI
  10.1111/his.12107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390310, KAKENHI-PROJECT-23592442, KAKENHI-PROJECT-24659724, KAKENHI-PROJECT-24659725, KAKENHI-PROJECT-24791696, KAKENHI-PROJECT-25293339, KAKENHI-PROJECT-25293340, KAKENHI-PROJECT-25861483
[Journal Article] Lipocalin2 enhances the matrix metalloproteinase-9 activity and invasion of extravillous trophoblasts under hypoxia2013
- Author(s)
  Kobara H, Miyamoto T, Suzuki A, Asaka R, Yamada Y, Ishikawa K, Kikuchi N, Ohira S, Shiozawa T
- Journal Title
  
  Placenta
  
  Volume: 34 Pages: 1036-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791696
[Journal Article] Lipocalin2 enhances the matrix metalloproteinase-9 activity and invasion of extravillous trophoblasts under hypoxia.2013
- Author(s)
  Kobara H, Miyamoto T, Suzuki A, Asaka R, Yamada Y, Ishikawa K, Kikuchi N, Ohira S, Shiozawa T.
- Journal Title
  
  Placenta
  
  Volume: 34(11) Issue: 11 Pages: 1036-43
- DOI
  10.1016/j.placenta.2013.08.004
- Data Source
  KAKENHI-PROJECT-23592442, KAKENHI-PROJECT-24659724, KAKENHI-PROJECT-24659725, KAKENHI-PROJECT-24791696, KAKENHI-PROJECT-25293339, KAKENHI-PROJECT-25293340, KAKENHI-PROJECT-25670698, KAKENHI-PROJECT-25861483, KAKENHI-PROJECT-25861484
[Presentation] Macrolide antibiotics enhance the oxidative stress tolerance of trophoblasts2023
- Author(s)
  Yasuhiro Tanaka, Tsutomu Miyamoto, Satoshi Yamada, Ryoichi Asaka, Hirofumi Ando, Kyosuke Kamijo, Natsuki Uchiyama, Yusuke Yokokawa, Manaka Shinagawa, Motoki Ono, Norihiko Kikuchi, Tanri Shiozawa
- Organizer
  International Federation of Placenta Associations Meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K08863
[Presentation] マクロライド系抗菌薬は絨毛細胞の酸化ストレス耐性を増強する2023
- Author(s)
  田中泰裕、宮本　強、山田諭、浅香亮一、安藤大史、上條恭佑、内山夏紀、横川裕亮、品川真奈花、小野元紀、菊地範彦、塩沢丹里
- Organizer
  第75回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-23K08863
[Presentation] ワサビ由来天然化合物6-MITCはNK細胞活性化を介して子宮体癌細胞の増殖を抑制する2022
- Author(s)
  小野元紀, 宮本強, 浅香亮一, 横川裕亮, 品川真奈花, 田中泰裕, 塩沢丹里
- Organizer
  第64回　日本婦人科腫瘍学会学術講演会
- Data Source
  KAKENHI-PROJECT-21K09537
[Presentation] ワサビ由来天然化合物6-MITCは子宮内膜癌細胞異種移植腫瘍に対してNK細胞活性増強を介した抗腫瘍効果を有する2021
- Author(s)
  小野元紀、宮本強、浅香亮一、品川真奈花、田中泰裕、竹内穂高、塩沢丹里
- Organizer
  第73回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-21K09537
[Presentation] 長寿遺伝子のSirtuin1の子宮内膜癌における発現と機能の検討2013
- Author(s)
  浅香亮一, 宮本強, 安藤大史, 石川香織, 山田靖, 塩沢丹里
- Organizer
  第18回生殖医学フォーラム
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-24791696
[Presentation] 卵巣明細胞癌発生に関与する新規候補遺伝子の機能的スクリーニング2013
- Author(s)
  安藤大史、宮本　強、山田　靖、鈴木昭久、浅香亮一、石川香織、小原久典、塩沢丹里
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25293340
[Presentation] Sirtuin1(SIRT1) inhibitor suppressrs tumor growth of endometrial carcinoma cell in nude mice.2013
- Author(s)
  Asaka R,Miyamoto T,Ando H,Yamada Y,David Hamisi Mvunta,Ishikawa K,Kobara H,Shiozawa T.
- Organizer
  第3回アジア婦人科腫瘍学会・第55回日本婦人科腫瘍学会学術講演会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24791696
[Presentation] 長寿遺伝子sirtuin1の子宮内膜癌細胞における増殖・抗癌剤耐性に関する作用の検討2013
- Author(s)
  浅香亮一, 宮本強, 石川香織, 山田靖, 小原久典, 塩沢丹里
- Organizer
  第12回日本婦人科がん分子標的研究会学術集会
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PROJECT-24791696
[Presentation] Sirtuin1(SIRT1) inhibitor suppressrs tumor growth of endometrial carcinoma cell in nude mice2013
- Author(s)
  Asaka R, Miyamoto T, Ando H, YamadaY, David Hamisi Mvunta, Ishikawa K, Kobara H, Shiozawa T
- Organizer
  第3回アジア婦人科腫瘍学会・第55回日本婦人科腫瘍学会学術講演会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24791696
[Presentation] SIRT1は子宮内膜癌細胞においてPI3KおよびMAPK経路を介して、増殖能亢進とシスプラチン耐性獲得に関与する2013
- Author(s)
  浅香亮一、宮本　強、安藤大史、石川香織、山田　靖、小原久典、塩沢丹里
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24791696
[Presentation] SIRT1は子宮内膜癌細胞において PI3K およびMAPK 経路を介して, 増殖能亢進とシスプラチン耐性獲得に関与する2013
- Author(s)
  浅香亮一, 宮本強, 安藤大史, 石川香織, 山田靖, 小原久典, 塩沢丹里
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24791696
[Presentation] Sirtuin1, a longevity gene, is over-expressed and enhances proliferation and survival of endometrial carcinoma cells via deacetylation of p532013
- Author(s)
  Asaka R, Miyamoto T, Ishikawa K, Yamada Y, Kobara H, Suzuki A, Taniguchi S, Shiozawa T
- Organizer
  American Assosiation for Cancer Research Annual Meeting 2013
- Place of Presentation
  ワシントン D.C
- Year and Date
  2013-04-07
- Data Source
  KAKENHI-PROJECT-24791696
[Presentation] Sirtuin1は子宮内膜癌のシスプラチン耐性に関与する2013
- Author(s)
  浅香亮一, 宮本強, 石川香織, 山田靖, 小原久典, 鈴木昭久, 塩沢丹里
- Organizer
  第65回日本産科婦人科学会学術講演会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24791696
[Presentation] Sirtuin1(SIRT1),a longevity gene,is over-expressed in endometrial carcinoma2012
- Author(s)
  Asaka R
- Organizer
  14th International Gynecologic Cancer Society(IGCS)
- Place of Presentation
  Vancouver
- Data Source
  KAKENHI-PROJECT-24791696
[Presentation] 正常子宮内膜および子宮内膜癌におけるsirtuin1発現の検討2012
- Author(s)
  浅香　亮一
- Organizer
  第64回日本産科婦人科学会学術講演会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24791696
[Presentation] 正常子宮内膜および子宮内膜癌における sirtuin1 発現の検討2012
- Author(s)
  浅香亮一, 宮本強, 鈴木昭久, 鹿島大靖, 塩沢丹里
- Organizer
  第64回日本産科婦人科学会学術講演会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24791696
[Presentation] Sirtuin1(SIRT1), a longevity gene, is over-expressed in endometrial carcinoma2012
- Author(s)
  Asaka R, Miymamoto T, Suzuki A, Ishikawa K, Yamada Y, Kobara H, Shiozawa T
- Organizer
  14th International Gynecologic Cancer Society(IGCS)
- Place of Presentation
  バンクーバー
- Data Source
  KAKENHI-PROJECT-24791696
[Presentation] 正常内膜および子宮内膜癌におけるSirtuin1(SIRT1)の発現と機能の検討2012
- Author(s)
  浅香亮一, 宮本強, 石川香織, 山田靖, 小原久典, 鈴木昭久, 塩沢丹里
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24791696
[Presentation] Sirtuin1, a longevity gene, is over-expressed and enhances proliferation and survival of endometrial carcinoma cells via deacetylation of p53
- Author(s)
  Asaka R,Miyamoto T, Ishikawa K,Yamada Y, Kobara H,Suzuki A, Taniguchi S,Shiozawa T.
- Organizer
  American Assosiation for Cancer Research Annual Meeting 2013
- Place of Presentation
  Washington, DC
- Data Source
  KAKENHI-PROJECT-24791696
[Presentation] Identification of novel genes involved in clear cell carcinogenesis of the overy using retrovirus-based cDNA expression library
- Author(s)
  Shiozawa T,Miyamoto T,Suzuki A,Asaka R.
- Organizer
  American Assosiation for Cancer Research Annual Meeting 2013
- Place of Presentation
  ワシントンD.C（アメリカ）
- Data Source
  KAKENHI-PROJECT-25293340

1. SHIOZAWA Tanri (20235493)

# of Collaborated Projects: 6 results

# of Collaborated Products: 10 results
2. 宮本強 (70418721)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
3. ANDO Hirofumi (80722925)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. 小野元紀 (10816432)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. SUZUKI Akihisa (10547095)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. Fuseya Chiho (50447736)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 鹿島大靖 (70464089)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 井田耕一 (10773442)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 丸喜明 (30742754)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 横川裕亮 (90974923)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 田中泰裕 (80869941)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 山田靖

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Asaka Ryoichi 浅香 亮一

ASAKA Ryoichi 浅香 亮一

Research Projects

Research Products

Co-Researchers

Development of an experimental model of gastric-type adenocarcinoma of the uterine cervix and its drug sensitivity

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

YAP/TAZを標的とした子宮頸部胃型腺癌の新規治療法の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of the effects of macrolide antimicrobial agents on oxidative stress tolerance in trophoblast cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research of antitumor effects of 6-MITC, a natural compound derived from wasabi, on endometrial cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The efficacy of novel ovarian cancer treatment targeting SIRT1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel anti-cancer drugs targeting cyclin A for endometrial carcinoma.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of SIRT1-function and the effect of SIRT1 inhibitor in endometrial cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a new drug for endometrial carcinoma targeting cycylin A

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the expression and function of SIRT1 in endometrial carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Anti-tumor effect of Wasabi component, 6-(methylsulfinyl) hexyl isothiocyanate, against endometrial carcinoma cells2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Elevated Serum Levels of Estradiol Induce Endometrial Hyperplasia Rather than Carcinoma in a Mouse Model Using a Carcinogen2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] SIRT1 Regulates the Chemoresistance and Invasiveness of Ovarian Carcinoma Cells2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Overexpression of SIRT1 is Associated With Poor Outcomes in Patients With Ovarian Carcinoma.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sirtuin 1 promotes the growth and cisplatin resistance of endometrial carcinoma cells: a novel therapeutic target.2015

Asaka Ryoichi 浅香亮一

ASAKA Ryoichi 浅香亮一