SAGANE Yoshimasa 相根義昌

… Alternative Names

相根義昌サガネヨシマサ

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Researcher Number	00624660
Other IDs	https://orcid.org/0000-0002-7815-3141
Affiliation (Current)	2025: 東京農業大学, 生物産業学部, 教授
Affiliation (based on the past Project Information) *help	2025: 東京農業大学, 生物産業学部, 教授 2022 – 2023: 東京農業大学, 生物産業学部, 教授 2013 – 2020: 東京農業大学, 生物産業学部, 教授
Review Section/Research Field	Principal Investigator Basic Section 49050:Bacteriology-related / Bacteriology (including mycology) Except Principal Investigator Bacteriology (including mycology) / Basic veterinary science/Basic zootechnical science
Keywords	Principal Investigator ボツリヌス食中毒 / ボツリヌス毒素 / 経口毒素 / ボツリヌス菌 / 血球凝集素 / ドラッグデリバリー / ムチン / 変異 / 一次構造解析 / タンパク質 … More / 細胞認識 / 翻訳後修飾 / 毒素複合体 / 蛋白質 / 経口輸送 / タンパク質の構造 / 経口毒性 / タンパク質分解酵素 / ボツリヌス毒素複合体 / ミオシン / 非毒非血球凝集素 / 抗体 / アクチンフィラメント / 細胞内輸送 / 消化管輸送 / タンパク質毒素 / 体内輸送 … More Except Principal Investigator ボツリヌス毒素 / 小腸上皮細胞 / ボツリヌス毒素複合体 / 小腸上皮組織 / エンドソーム / タンパク質複合体 / 空胞化 / 細胞毒性 / ボツリヌス食中毒 / トランスサイトーシス / 細胞内シグナル / 腸管吸収 / MAPキナーゼ / 透過性 / エンドサイトーシス / 家畜ボツリヌス症 Less

経口毒性強化型ボツリヌス毒素複合体の体内侵入メカニズムの解明Principal Investigator
- Principal Investigator
  
  相根義昌
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Tokyo University of Agriculture
Functional analysis of botulinum toxin complex with enhanced oral toxicityPrincipal Investigator
- Principal Investigator
  
  相根義昌
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Tokyo University of Agriculture
Novel "Functional shift" in Cell-Recognition found in Botulinum Neurotoxin ComplexPrincipal Investigator
- Principal Investigator
  
  SAGANE Yoshimasa
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Tokyo University of Agriculture
Molecules involved in intracellular trafficking of botulinum neurotoxin binding protein NTNHAPrincipal Investigator
- Principal Investigator
  
  Sagane Yoshimasa
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Tokyo University of Agriculture
Involvement of nontoxic protein in botulinum toxin complex on digestive injury in botulism food poisoning
- Principal Investigator
  
  WATANABE Toshihiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Tokyo University of Agriculture
Cell-layer transport mechanism of botulinum neurotoxin-binding protein, nontoxic nonhemagglutininPrincipal Investigator
- Principal Investigator
  
  SAGANE Yoshimasa
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Tokyo University of Agriculture
Signal transduction of intestinal epithelial cells involved in absorption of botulinum toxin.
- Principal Investigator
  
  NIWA Koichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Tokyo University of Agriculture

All 2023 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] Variants of hemagglutinin-33 in the serotype C botulinum progenitor toxin complex boost its oral toxicity2023
- Author(s)
  Shura Karatsu, Shin-Ichiro Miyashita, Tsuyoshi Hata, I-Hsun Huang, Keita Hosoya, Yoshimasa Sagane
- Journal Title
  
  Food Preservation Science
  
  Volume: 49 Pages: 19-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07057
[Journal Article] Atomic force microscopic image data of botulinum neurotoxin complexes with different molecular sizes2019
- Author(s)
  Shin-Ichiro Miyashita, Yoshimasa Sagane, Takamasa Uchino, Shura Karatsu, Keita Hosoya, Ihsun Huang, Koichi Niwa, Toshihiro Watanabe, Yoichi Niimura, Tomonori Suzuki
- Journal Title
  
  Data in Brief
  
  Volume: 25 Pages: 104193-104193
- DOI
  10.1016/j.dib.2019.104193
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07123
[Journal Article] Reversible Association of the Hemagglutinin Subcomplex, HA-33/HA-17 Trimer, with the Botulinum Toxin Complex2017
- Author(s)
  Sagane Y, Mutoh S, Koizumi R, Suzuki T, Miyashita S, Miyata K, Ohyama T, Niwa K, Watanabe T
- Journal Title
  
  The Protein Journal
  
  Volume: 36 Issue: 5 Pages: 417-424
- DOI
  10.1007/s10930-017-9733-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08474, KAKENHI-PROJECT-15K08475
[Journal Article] Building-block architecture of botulinum toxin complex: Conformational changes provide insights into the hemagglutination ability of the complex2017
- Author(s)
  Suzuki T, Sagane Y, Matsumoto T, Hasegawa K, Yamano A, Niwa K, Watanabe T
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 9 Pages: 67-71
- DOI
  10.1016/j.bbrep.2016.11.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08474, KAKENHI-PROJECT-15K08475
[Journal Article] Construction of ‘‘Toxin Complex’’ in a Mutant Serotype C Strain of Clostridium botulinum Harboring a Defective Neurotoxin Gene2016
- Author(s)
  Tomonori Suzuki, Thomas Nagano, Koichi Niwa, Masataka Uchino, Motohiro Tomizawa, Yoshimasa Sagane, and Toshihiro Watanabe
- Journal Title
  
  Current Microbiology
  
  Volume: 74 Issue: 1 Pages: 49-54
- DOI
  10.1007/s00284-016-1150-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08474, KAKENHI-PROJECT-15K08475
[Journal Article] "Non-Toxic" Proteins of the Botulinum Toxin Complex Exert In-vivo Toxicity.2016
- Author(s)
  Shin-Ichiro Miyashita, Yoshimasa Sagane, Tomonori Suzuki, Takashi Matsumoto, Koichi Niwa, and Toshihiro Watanabe
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1
- DOI
  10.1038/srep31043
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08474, KAKENHI-PROJECT-15K08475
[Journal Article] Conformational divergence in the HA-33/HA-17 trimer of serotype C and D botulinum toxin complex.2016
- Author(s)
  Yoshimasa Sagane, Shintaro Hayashi, Tomonori Akiyama, Takashi Matsumoto, Kimiko Hasegawa, Akihito Yamano, Tomonori Suzuki, Koichi Niwa, Toshihiro Watanabe, and Shunsuke Yajima
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 476 Issue: 4 Pages: 280-285
- DOI
  10.1016/j.bbrc.2016.05.113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08474, KAKENHI-PROJECT-15K08475
[Journal Article] Data describing inhibitory profiles of sugars against hemagglutination by the botulinum toxin complex of Clostridium botulinum serotypes C and D2016
- Author(s)
  Yoshimasa Sagane, Minoru Ito, Keita Miyata, Tomonori Suzuki, Koichi Niwa, Suguru Oguri, and Toshihiro Watanabe
- Journal Title
  
  Data in Brief
  
  Volume: 9 Pages: 413-416
- DOI
  10.1016/j.dib.2016.09.014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08474, KAKENHI-PROJECT-15K08475
[Journal Article] Isolation of botulinolysin, a thiol-activated hemolysin, from serotype D Clostridium botulinum: A species-specific gene duplication in Clostridia2016
- Author(s)
  Tomonori Suzuki, Thomas Nagano, Koichi Niwa, Shingo Mutoh, Masataka Uchino, Motohiro Tomizawa, Yoshimasa Sagane, and Toshihiro Watanabe
- Journal Title
  
  Microbiological Research
  
  Volume: 193 Pages: 20-29
- DOI
  10.1016/j.micres.2016.08.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08474, KAKENHI-PROJECT-15K08475
[Journal Article] Hemagglutinin Gene Shuffling among Clostridium botulinumSerotypes C and D Yields Distinct Sugar Recognition of the Botulinum Toxin Complex2015
- Author(s)
  Miyata K, Suzuki T, Hayashi S, Miyashita S, Ohyama T, Niwa K, Watanabe T, Sagane Y
- Journal Title
  
  FEMS Pathogens and Disease
  
  Volume: 73 Issue: 7 Pages: ftv054-ftv054
- DOI
  10.1093/femspd/ftv054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08474
[Journal Article] 87. Purification, crystallization and preliminary X-ray analysis of a HA17-HA70 (HA2-HA3) complex from Clostridium botulinum type C progenitor toxin.2014
- Author(s)
  Chikako Iwasa, Takashi Tonozuka, Masaya Shinoda, Yoshimasa Sagane, Koichi Niwa, Toshihiro Watanabe, Hiromi Yoshida, Shigehiro Kamitori, Toshifumi Takao, Keiji Oguma, Atsushi Nishikawa
- Journal Title
  
  Acta Crystallographica
  
  Volume: F70 Issue: 1 Pages: 64-67
- DOI
  10.1107/s2053230x13032378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24658284, KAKENHI-PROJECT-25860325
[Journal Article] Host-cell specificity and transcytosis of nontoxic nonhemagglutinin protein of botulinum neurotoxin serotype D2014
- Author(s)
  Shin-Ichiro Miyashita, Koichi Niwa, Toshihiro Watanabe, and Yoshimasa Sagane
- Journal Title
  
  FEMS Microbiology Letter
  
  Volume: 357 Pages: 115-122
- DOI
  10.1111/1574-6968.12527
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25860325
[Journal Article] Identification of the interaction region between hemagglutinin components of the botulinum toxin complex2014
- Author(s)
  Suzuki T, Miyashita S, Hayashi S, Miyata K, Inui K, Kondo Y, Miyazaki S, Ohyama T, Niwa K, Watanabe T, Sagane Y
- Journal Title
  
  International Journal of Biological Macromolecules
  
  Volume: 65 Pages: 284-288
- DOI
  10.1016/j.ijbiomac.2014.01.052
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25860320, KAKENHI-PROJECT-25860325
[Journal Article] Crystallization and preliminary X-ray analysis of a novel haemagglutinin component of the toxin complex of serotype C Clostridium botulinum.2014
- Author(s)
  Shintaro Hayashi, Tomonori Akiyama, Yoshimasa Sagane, Shin-Ichiro Miyashita, Toshihiro Watanabe, Shunsuke Yajima, and Koichi Niwa
- Journal Title
  
  Acta Crystallography F Structural Biology Communication
  
  Volume: 70 Issue: 3 Pages: 370-373
- DOI
  10.1107/s2053230x14003094
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860325
[Journal Article] Botulinum Toxin Complex Increases Paracellular Permeability in Intestinal Epithelial Cells via Activation of p38 Mitogen-Activated Protein Kinase2013
- Author(s)
  Miyashita S-I., Sagane Y., Inui K., Hayashi S., Miyata K., Suzuki T., Ohyama T., Watanabe T., Niwa K.
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 75 Issue: 12 Pages: 1637-1642
- DOI
  10.1292/jvms.13-0164
- NAID
  130003362264
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24580432, KAKENHI-PROJECT-25860325
[Journal Article] Transport of the botulinum neurotoxin-associating protein, nontoxic nonhemagglutinin, across the rat small intestinal epithelial cell monolayer2013
- Author(s)
  Shin-Ichiro Miyashita, Yoshimasa Sagane, Koichi Niwa, Toshihiro Watanabe
- Journal Title
  
  FEMS Microbiology Letter
  
  Volume: 346 Issue: 1 Pages: 73-80
- DOI
  10.1111/1574-6968.12205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860325
[Journal Article] Sugar-induced conformational change found in the HA-33/HA-17 trimer of the botulinum toxin complex2013
- Author(s)
  Yoshimasa Sagane, Shintaro Hayash, Takashi Matsumoto, Shin-ichro Miyashita, Ken Inui, Keita Miyata, Shunsuke Yajima, Tomonori Suzuki, Kimiko Hasegawa, Akihito Yamano, Atushi Nishikawa, Tohru Ohyama, Toshihiro Watanabe, Koichi Niwa
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 438 Issue: 3 Pages: 483-487
- DOI
  10.1016/j.bbrc.2013.07.112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24658284, KAKENHI-PROJECT-25860320, KAKENHI-PROJECT-25860325
[Presentation] C型ボツリヌス菌Yoichi株の血球凝集素33の大腸菌組換え発現の構築と精製2023
- Author(s)
  畑剛士，宮下慎一郎，唐津修羅，黄インシュン，長島有希，諸菱環，細谷圭汰，本多亮鷹，相根義昌
- Organizer
  第96回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-22K07057
[Presentation] ボツリヌス毒素複合体の小腸上皮細胞に対する細胞毒性2018
- Author(s)
  菅原千広、栗原淳、黄インシュン、唐津修羅、細谷圭汰、渡辺薫、相根義昌、丹羽光一
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K07123
[Presentation] ボツリヌス神経毒素結合タンパク質NTNHAのアクチン依存性細胞内輸送2018
- Author(s)
  渡辺薫、栗原淳、細谷圭汰、唐津修羅、菅原千広、黄インシュン、丹羽光一、相根義昌
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K07123
[Presentation] ボツリヌス毒素複合体の各種上皮細胞に対する影響2018
- Author(s)
  黄インシュン、栗原淳、菅原千広、細谷圭汰、唐津修羅、渡辺薫、丹羽光一、相根義昌
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K07123
[Presentation] ボツリヌスC型菌Yoichi株が産生する毒素複合体の構造と機能の変化2018
- Author(s)
  唐津修羅、細谷圭汰、黄インシュン、菅原千広、栗原淳、渡辺薫、丹羽光一、相根義昌
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K07123
[Presentation] ボツリヌスD型菌4947株培養液中に出現するボツリヌス毒素タンパク質複合体の経時変化2018
- Author(s)
  細谷圭汰、唐津修羅、栗原淳、菅原千広、黄インシュン、渡辺薫、丹羽光一、相根義昌
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K07123
[Presentation] ボツリヌスD型神経毒素複合体によって誘導される小腸上皮細胞の細胞骨格の形状変化2018
- Author(s)
  栗原淳、黄インシュン、細谷圭汰、菅原千広、唐津修羅、渡辺薫、丹羽光一、相根義昌
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K07123
[Presentation] “Non-toxic” proteins of the botulinum toxin complex exert cytotoxicity with vacuole formation in the cell.2017
- Author(s)
  Sagane, Y., Miyashita, S. -I., Kurihara, A., Sugawara, C., Hosoya, K., Karatsu, S., Niwa, K., Watanabe, T.
- Organizer
  10th International Conference on the Molecular Biology and Pathogenesis of the Clostridia.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08474
[Presentation] Internalization and intercellular trafficking of the serotype D botulinum neurotoxin binding protein, nontoxic nonhemagglutinin, in epithelial and endothelial cells.2017
- Author(s)
  Sagane, Y., Miyashita, S. -I., Hosoya, K., Karatsu, S., Kurihara, A., Sugawara, C., Niwa, K., Watanabe, T.
- Organizer
  10th International Conference on the Molecular Biology and Pathogenesis of the Clostridia.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08474
[Presentation] Internalization and intercellular trafficking of the serotype D botulinum neurotoxin binding protein, nontoxic nonhemagglutinin, in epithelial and endothelial cells.2017
- Author(s)
  Sagane, Y., Miyashita, S. -I., Hosoya, K., Karatsu, S., Kurihara, A., Sugawara, C., Niwa, K., Watanabe, T.
- Organizer
  10th International Conference on the Molecular Biology and Pathogenesis of the Clostridia.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08475
[Presentation] “Non-toxic” proteins of the botulinum toxin complex exert cytotoxicity with vacuole formation in the cell.2017
- Author(s)
  Sagane, Y., Miyashita, S. -I., Kurihara, A., Sugawara, C., Hosoya, K., Karatsu, S., Niwa, K., Watanabe, T.
- Organizer
  10th International Conference on the Molecular Biology and Pathogenesis of the Clostridia.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08475
[Presentation] D型ボツリヌス神経毒素結合タンパク質非毒非血球凝集素のヒト大腸癌細胞への結合および透過2014
- Author(s)
  宮下慎一郎，相根義昌，林慎太郎，鈴木智典，丹羽光一，渡部俊弘
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25860325
[Presentation] D 型ボツリヌス神経毒素結合タンパク質非毒非血球凝集素のヒト大腸癌細胞への結合および透過2014
- Author(s)
  宮下慎一郎, 相根義昌, 林慎太郎, 鈴木智典, 丹羽光一, 渡部俊弘
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  タワーホール船堀（東京都）
- Data Source
  KAKENHI-PROJECT-24580432
[Presentation] ボツリヌスC型菌Yoichi株の産生するHA-33/HA-17複合体の構造2014
- Author(s)
  林慎太郎, 相根義昌，松本崇, 秋山友了，宮下慎一郎，長谷川仁子，山野昭人，矢嶋俊介, 渡部俊弘，丹羽光一
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25860325
[Presentation] ボツリヌスC型菌Yoichi株が産生するHA-33の結晶化2013
- Author(s)
  林慎太郎, 相根義昌, 秋山友了, 宮下慎一郎, 鈴木智典，矢嶋俊介, 渡部俊弘, 丹羽光一.
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25860325
[Presentation] D 型ボツリヌス神経毒素結合タンパク質 NTNHA はラット小腸上皮細胞へ結合し細胞層を透過する2013
- Author(s)
  宮下慎一郎, 相根義昌, 林慎太郎, 鈴木智典, 丹羽光一 , 渡部俊弘
- Organizer
  第80回日本細菌学会北海道支部学術総会
- Place of Presentation
  東京農大生物産業学部（網走市）
- Data Source
  KAKENHI-PROJECT-24580432
[Presentation] D型ボツリヌス神経毒素結合タンパク質 NTNHAはラット小腸上皮細胞へ結合し細胞層を透過する.2013
- Author(s)
  宮下慎一郎, 相根義昌, 林慎太郎, 鈴木智典，丹羽光一, 渡部俊弘.
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25860325
[Presentation] D型ボツリヌス毒素の小腸上皮細胞層透過に関与する細胞内分子機構2012
- Author(s)
  狩野聡史、相根義昌、宮下慎一郎、犬井健、川根武紘、栗原小百合、林慎太郎、渡部俊弘、丹羽光一
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24580432
[Presentation] ボツリヌスC型菌Yoichi株が産生するHA-33の構造解析
- Author(s)
  林慎太郎, 相根義昌, 松本崇, 秋山友了, 宮下慎一郎, 長谷川仁子, 山野昭人, 矢嶋俊介, 渡部俊弘, 丹羽光一
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25860325
[Presentation] ボツリヌスC 型菌Yoichi 株の産生するHA-33/HA-17 複合体の構造解析
- Author(s)
  林慎太郎，相根義昌，松本崇，秋山友了，宮下慎一郎，武藤信吾，山野昭人，矢嶋俊介，渡部俊弘，丹羽光一
- Organizer
  第88回日本細菌学会総会
- Place of Presentation
  岐阜
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25860325
[Presentation] D型ボツリヌス神経毒素結合タンパク質非毒非血球凝集素の細胞種特異的なトランスサイトーシス
- Author(s)
  宮下慎一郎, 林慎太郎, 丹羽光一, 渡部俊弘, 相根義昌
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25860325
[Presentation] D 型ボツリヌス毒素複合体による小腸上皮の透過性上昇における MAP キナーゼの関与
- Author(s)
  宮下慎一郎、丹羽光一、相根義昌、林慎太郎、渡部俊弘
- Organizer
  第 81 回日本細菌学会北海道支部学術総会
- Place of Presentation
  札幌医科大学、札幌
- Year and Date
  2014-08-29 – 2014-08-30
- Data Source
  KAKENHI-PROJECT-24580432

1. NIWA Koichi (20301012)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
2. WATANABE Toshihiro (80175695)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
3. MUTOH Shingo (20749890)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. SUZUKI Tomonori (90453836)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
5. 宮下慎一郎 (20883292)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 西河淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

SAGANE Yoshimasa 相根 義昌

相根 義昌 サガネ ヨシマサ

Research Projects

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Co-Researchers

経口毒性強化型ボツリヌス毒素複合体の体内侵入メカニズムの解明Principal Investigator

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Functional analysis of botulinum toxin complex with enhanced oral toxicityPrincipal Investigator

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Novel "Functional shift" in Cell-Recognition found in Botulinum Neurotoxin ComplexPrincipal Investigator

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Molecules involved in intracellular trafficking of botulinum neurotoxin binding protein NTNHAPrincipal Investigator

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Involvement of nontoxic protein in botulinum toxin complex on digestive injury in botulism food poisoning

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Cell-layer transport mechanism of botulinum neurotoxin-binding protein, nontoxic nonhemagglutininPrincipal Investigator

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Signal transduction of intestinal epithelial cells involved in absorption of botulinum toxin.

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[Journal Article] Variants of hemagglutinin-33 in the serotype C botulinum progenitor toxin complex boost its oral toxicity2023

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[Journal Article] Atomic force microscopic image data of botulinum neurotoxin complexes with different molecular sizes2019

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[Journal Article] Reversible Association of the Hemagglutinin Subcomplex, HA-33/HA-17 Trimer, with the Botulinum Toxin Complex2017

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[Journal Article] Building-block architecture of botulinum toxin complex: Conformational changes provide insights into the hemagglutination ability of the complex2017

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[Journal Article] Construction of ‘‘Toxin Complex’’ in a Mutant Serotype C Strain of Clostridium botulinum Harboring a Defective Neurotoxin Gene2016

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[Journal Article] "Non-Toxic" Proteins of the Botulinum Toxin Complex Exert In-vivo Toxicity.2016

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[Journal Article] Conformational divergence in the HA-33/HA-17 trimer of serotype C and D botulinum toxin complex.2016

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SAGANE Yoshimasa 相根義昌

相根義昌サガネヨシマサ