Yoshikawa Toshiaki 吉川聡明

… Alternative Names

吉川聡明ヨシカワトシアキ

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Researcher Number	00625957
Affiliation (Current)	2025: 慶應義塾大学, 医学部(信濃町), 共同研究員
Affiliation (based on the past Project Information) *help	2023: 慶應義塾大学, 医学部(信濃町), 助教 2020 – 2021: 愛知県がんセンター(研究所), 腫瘍免疫応答研究分野, 研究員 2019: 国立研究開発法人国立がん研究センター, 先端医療開発センター, 研究員 2015 – 2017: 国立研究開発法人国立がん研究センター, 先端医療開発センター, 研究員 2014: 独立行政法人国立がん研究センター, 早期・探索臨床研究センター, 研究員
Review Section/Research Field	Principal Investigator Respiratory surgery / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 55040:Respiratory surgery-related
Keywords	Principal Investigator 腫瘍浸潤リンパ球 / 肺がん / 自己腫瘍反応性 / T細胞移入療法 / 個別化 / 遺伝子変異由来抗原 / 遺伝子改変 / 疲弊化 / T細胞機能改善 / 疲弊化解除 … More / TIL / ネオアンチゲン / 個別化医療 / 腫瘍免疫学 Less

腫瘍反応性T細胞の濃縮と機能改善に基づく婦人科がん個別化T細胞療法の新規開発Principal Investigator
- Principal Investigator
  
  吉川聡明
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Keio University
Developing a personalized immunotherapy: Identification of tumor reactive CTLsPrincipal Investigator
- Principal Investigator
  
  Yoshikawa Toshiaki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Aichi Cancer Center Research Institute
  National Cancer Center Japan
Developing a personalized immunotherapy for lung cancer patients: Identification of tumor reactive CTLsPrincipal Investigator
- Principal Investigator
  
  Yoshikawa Toshiaki
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory surgery
- Research Institution
  National Cancer Center Japan
Development of adoptive T cell therapy for lung cancer that have complicated mutationsPrincipal Investigator
- Principal Investigator
  
  Yoshikawa Toshiaki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory surgery
- Research Institution
  National Cancer Center Japan

All 2024 2023 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation Book Other

[Book] Development of glypican-3-targeted cancer immunotherapy.2015
- Author(s)
  Yoshikawa T, Sawada Y, Sakai M, Ofuji K, Nakatsura T.
- Total Pages
  11
- Publisher
  Inflammation and Immunity in Cancer, Springer, Germany
- Data Source
  KAKENHI-PROJECT-26861133
[Journal Article] Development of a chimeric cytokine receptor that captures IL-6 and enhances the antitumor response of CAR-T cells2024
- Author(s)
  Yoshikawa Toshiaki、Ito Yusuke、Wu Zhiwen、Kasuya Hitomi、Nakashima Takahiro、Okamoto Sachiko、Amaishi Yasunori、Zhang Haosong、Li Yang、Matsukawa Tetsuya、Inoue Satoshi、Kagoya Yuki
- Journal Title
  
  Cell Reports Medicine
  
  Volume: Apr 16 Issue: 5 Pages: 101526-101526
- DOI
  10.1016/j.xcrm.2024.101526
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06710, KAKENHI-PROJECT-22K15575, KAKENHI-PROJECT-23K24171
[Journal Article] Aberrant splicing isoforms detected by full-length transcriptome sequencing as transcripts of potential neoantigens in non-small cell lung cancer.2021
- Author(s)
  Oka M, Xu L, Suzuki T, Yoshikawa T, Sakamoto H, Uemura H, Yoshizawa AC, Suzuki Y, Nakatsura T, Ishihama Y, Suzuki A, Seki M
- Journal Title
  
  Genome Biol.
  
  Volume: 22(1):9 Issue: 1 Pages: 1-9
- DOI
  10.1186/s13059-020-02240-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09297, KAKENHI-PLANNED-17H06306, KAKENHI-PROJECT-19K16108, KAKENHI-PROJECT-19K16792, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-18K08637, KAKENHI-ORGANIZER-17H06299
[Journal Article] Peptide vaccine as an adjuvant therapy for glypican-3 positive hepatocellular carcinoma induces peptide specific CTLs and improves long prognosis.2020
- Author(s)
  Taniguchi M, Mizuno S, Yoshikawa T, Fujinami N, Sugimoto M, Kobayashi S, Takahashi S, Konishi M, Gotohda N, Nakatsura T
- Journal Title
  
  Cancer Sci.
  
  Volume: 111(8) Issue: 8 Pages: 2747-2759
- DOI
  10.1111/cas.14497
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09297
[Journal Article] Efficacy of immunotherapy targeting the neoantigen derived from EGFR T790M/C797S mutation in non-small cell lung cancer.2020
- Author(s)
  Akazawa Y, Saito Y, Yoshikawa T, saito K, Nosaka K, Shimomura M, Mizuno S, Nakamoto Y, Nakatsura T.
- Journal Title
  
  Cancer Sci.
  
  Volume: 111(8) Issue: 8 Pages: 2736-2746
- DOI
  10.1111/cas.14451
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09297
[Journal Article] Tumor-infiltrating T cells concurrently overexpress CD200R with immune checkpoints PD-1, CTLA-4 and TIM-3 in　non-small cell lung cancer.2020
- Author(s)
  Su Y, Yamazaki S, Morisue R, Suzuki J, Yoshikawa T, Nakatsura T, Tsuboi M, Ochiai A, Ishii G
- Journal Title
  
  Pathobiology
  
  Volume: 1-10 Issue: 3 Pages: 1-10
- DOI
  10.1159/000511557
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09297
[Journal Article] Efficacy of the NCCV Cocktail‐1 vaccine for refractory pediatric solid tumors: A phase I clinical trial2019
- Author(s)
  Akazawa Yu、Hosono Ako、Yoshikawa Toshiaki、Kaneda Hide、Nitani Chika、Hara Junichi、Kinoshita Yoshiaki、Kohashi Kenichi、Manabe Atsushi、Fukutani Miki、Wakabayashi Masashi、Sato Akihiro、Shoda Kayoko、Shimomura Manami、Mizuno Shoichi、Nakamoto Yasunari、Nakatsura Tetsuya
- Journal Title
  
  Cancer Science
  
  Volume: 110 Issue: 12 Pages: 3650-3662
- DOI
  10.1111/cas.14206
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09297, KAKENHI-PROJECT-17K08722
[Journal Article] Heat shock protein 105 peptide vaccine could induce antitumor immune reactions in a phase I clinical trial2019
- Author(s)
  Shimizu Yasuhiro、Yoshikawa Toshiaki、Kojima Takashi、Shoda Kayoko、Nosaka Kazuto、Mizuno Shoichi、Wada Satoshi、Fujimoto Yuki、Sasada Tetsuro、Kohashi Kenichi、Bando Hideaki、Endo Itaru、Nakatsura Tetsuya
- Journal Title
  
  Cancer Science
  
  Volume: 110 Issue: 10 Pages: 3049-3060
- DOI
  10.1111/cas.14165
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09297, KAKENHI-PROJECT-17H04278, KAKENHI-PROJECT-17K08722, KAKENHI-PROJECT-18K19490
[Journal Article] Cancer Immunotherapy Targeted Glypican-3 or Neoantigens.2018
- Author(s)
  Shimizu Y, Suzuki T, Yoshikawa T, Tsuchiya N, Sawada Y, Endo I, Nakatsura T.
- Journal Title
  
  Cancer Sci.
  
  Volume: 109(3) Issue: 3 Pages: 531-541
- DOI
  10.1111/cas.13485
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19990, KAKENHI-PROJECT-18K08637
[Journal Article] Perioperative plasma glypican-3 level may enable prediction of the risk of recurrence after surgery in patients with stage I hepatocellular carcinoma.2017
- Author(s)
  Ofuji K, Saito K, Suzuki S, Shimomura M, Shirakawa H, Nobuoka D, Sawada Y, Yoshimura M, Tsuchiya N, Takahashi M, Yoshikawa T, Tada Y, Konishi M, Takahashi S, Gotohda N, Nakamoto Y, Nakatsura T.
- Journal Title
  
  Oncotarget.
  
  Volume: in press Issue: 23 Pages: 37835-37844
- DOI
  10.18632/oncotarget.14271
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26670379, KAKENHI-PROJECT-16K19990
[Journal Article] Phase I study of glypican-3-derived peptide vaccine therapy for patients with refractory pediatric solid tumors2017
- Author(s)
  Tsuchiya Nobuhiro、Hosono Ako、Yoshikawa Toshiaki、Shoda Kayoko、Nosaka Kazuto、Shimomura Manami、Hara Junichi、Nitani Chika、Manabe Atsushi、Yoshihara Hiroki、Hosoya Yosuke、Kaneda Hide、Kinoshita Yoshiaki、Kohashi Kenichi、Yoshimura Kenichi、Fujinami Norihiro、Saito Keigo、Mizuno Shoichi、Nakatsura Tetsuya
- Journal Title
  
  OncoImmunology
  
  Volume: 7 Issue: 1 Pages: e1377872-e1377872
- DOI
  10.1080/2162402x.2017.1377872
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11347, KAKENHI-PROJECT-17K08722, KAKENHI-PROJECT-16K19990
[Journal Article] Immunological efficacy of glypican-3 peptide vaccine in patients with advanced hepatocellular carcinoma.2017
- Author(s)
  Tsuchiya N, Yoshikawa T, Fujinami N, Saito K, Mizuno S, Sawada Y, Endo I, Nakatsura T.
- Journal Title
  
  OncoImmunology.
  
  Volume: 6(10) Issue: 10 Pages: e1346764-e1346764
- DOI
  10.1080/2162402x.2017.1346764
- NAID
  130006513890
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19990
[Journal Article] Vaccination with liposome-coupled glypican-3-derived epitope peptide stimulates cytotoxic T lymphocytes and inhibits GPC3-expressing tumor growth in mice.2016
- Author(s)
  Iwama T, Uchida T, Sawada Y, Tsuchiya N, Sugai S, Fujinami N, Shimomura M, Yoshikawa T, Zhang R, Uemura Y, Nakatsura T.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 469(1) Issue: 1 Pages: 138-43
- DOI
  10.1016/j.bbrc.2015.11.084
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H06881, KAKENHI-PROJECT-26861133, KAKENHI-PROJECT-26462078
[Journal Article] Hepatocellular carcinoma cell sensitivity to Vg9Vd2 T lymphocyte-mediated killing is increased by zoledronate.2016
- Author(s)
  Sugai S, Yoshikawa T, Iwama T, Tsuchiya N, Ueda N, Fujinami N, Shimomura M, Zhang R, Kaneko S, Uemura Y, Nakatsura T.
- Journal Title
  
  Int J Oncol.
  
  Volume: 48 (5) Issue: 5 Pages: 1794-1804
- DOI
  10.3892/ijo.2016.3403
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462078, KAKENHI-PROJECT-15H06881, KAKENHI-PROJECT-26670578, KAKENHI-PROJECT-26861133, KAKENHI-PROJECT-26293357
[Journal Article] Enhancement of anti tumor effect by peptide vaccine therapy in combination with anti-CD4 antibody: Study in a murine model.2016
- Author(s)
  Fujinami N, Yoshikawa T, Sawada Y, Shimomura M, Iwama T, Sugai S, Kitano S, Uemura Y, Nakatsura T.
- Journal Title
  
  Biochemistry and Biophysics Reports.
  
  Volume: 5 Pages: 482-491
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26861133
[Journal Article] Programmed death-1 blockade enhances the antitumor effects of peptide vaccine-induced peptide-specific cytotoxic T lymphocytes.2015
- Author(s)
  Sawada Y, Yoshikawa T, Shimomura M, Iwama T, Endo I, Nakatsura T.
- Journal Title
  
  Int. J. Oncol.
  
  Volume: 46 Issue: 1 Pages: 28-36
- DOI
  10.3892/ijo.2014.2737
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26861133
[Journal Article] Detection and preliminary evaluation of circulating tumor cells in the peripheral blood of patients with eight types of cancer using a telomerase-specific adenovirus.2014
- Author(s)
  Yabusaki M, Sato J, Kohyama A, Kojima T, Nobuoka D, Yoshikawa T, Sawada Y, Murakami K, Gohda K, Okegawa T, Nakamura M, Takamatsu K, Ito M, Kaneko K, Nakatsura T.
- Journal Title
  
  Oncol. Rep.
  
  Volume: 32 Issue: 5 Pages: 1772-1778
- DOI
  10.3892/or.2014.3436
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26861133
[Journal Article] Large-scale expansion of γδ T cells and peptide-specific cytotoxic T cells using zoledronate for adoptive immunotherapy.2014
- Author(s)
  Yoshikawa T, Takahara M, Tomiyama M, Nieda M, Maekawa R, Nakatsura T.
- Journal Title
  
  Int. J. Oncol.
  
  Volume: 45 Issue: 5 Pages: 1847-1856
- DOI
  10.3892/ijo.2014.2634
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26861133
[Journal Article] Critical analysis of the potential of targeting GPC3 in hepatocellular carcinoma.2014
- Author(s)
  Ofuji K, Saito K, Yoshikawa T, Nakatsura T.
- Journal Title
  
  Journal of Hepatocellular Carcinoma.
  
  Volume: 1 Pages: 35-42
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26861133
[Journal Article] A peptide antigen derived from EGFR T790M is immunogenic in non small cell lung cancer.2014
- Author(s)
  Ofuji K, Tada Y, Yoshikawa T, Shimomura M, Yoshimura M, Saito K, Nakamoto Y, Nakatsura T
- Journal Title
  
  Int. J. Oncol.
  
  Volume: 46(2) Issue: 2 Pages: 497-504
- DOI
  10.3892/ijo.2014.2787
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293171, KAKENHI-PROJECT-26670379, KAKENHI-PROJECT-26861133
[Presentation] A novel chimeric cytokine receptor-engineered CAR-T cells with potent cytotoxicity and reduced cytokine release syndrome2023
- Author(s)
  Toshiaki Yoshikawa, Sachiko Okamoto, Yasunori Amaishi, Yuki Kagoya
- Organizer
  第27回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-23K06710
[Presentation] Epigenetic modification of antitumor T cells for optimal adoptive immunotherapy2021
- Author(s)
  Toshiaki Yoshikawa, Zhiwen Wu, Hirokazu Matsushita, Waki Hosoda, Shiro Suzuki, Yuki Kagoya
- Organizer
  第80回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09297
[Presentation] エピジェネティック因子修飾による抗腫瘍T細胞の機能改善2021
- Author(s)
  吉川聡明、呉智聞、松下博和、鈴木史朗、籠谷勇紀
- Organizer
  第18回日本免疫治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09297
[Presentation] Epigenetic modification of antitumor T cells to induce durable clinical response in adoptive immunotherapy2021
- Author(s)
  Toshiaki Yoshikawa, Zhiwen Wu, Hirokazu Matsushita, Waki Hosoda, Shiro Suzuki, Yuki Kagoya
- Organizer
  第25回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-19K09297
[Presentation] ネオアンチゲンを標的とした完全個別化がんペプチドワクチンの開発 -ネオアンチゲンの予測とヒトHLA発現マウスを用いた抗原性の評価-2020
- Author(s)
  鈴木利宙、中島裕理、下村真菜美、吉川聡明、平糠和志、山田崇、渡邊典子、三嶋雄二、中村徳弘、中面哲也
- Organizer
  第17回日本免疫治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09297
[Presentation] ネオアンチゲンを標的とした完全個別化がんペプチドワクチンの開発 ― 肝細胞がんにおけるネオアンチゲンの予測とその抗原性の評価に関して2020
- Author(s)
  藤浪紀洋, 鈴木利宙, 下村真菜美, 中島裕理, 吉川聡明, 平糠和志, 山田崇, 中面哲也
- Organizer
  第40回日本分子腫瘍マーカー研究会
- Data Source
  KAKENHI-PROJECT-19K09297
[Presentation] ナノポアシークエンサーを用いた肺がんにおける異常アイソフォームとネオ抗原の同定2020
- Author(s)
  岡実穂, 鈴木利宙, 吉川聡明, 中面哲也, 鈴木絢子, 鈴木穣, 関真秀
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09297
[Presentation] ネオアンチゲンを標的とした完全個別化がんペプチドワクチンの開発―ネオアンチゲンの予測と患者末梢血を用いた抗原性の評価2020
- Author(s)
  中島裕理、鈴木利宙、下村真菜美、上田詩歩、佐々木諒子、吉川聡明、平糠和志、山田崇、中面哲也
- Organizer
  第17回日本免疫治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09297
[Presentation] 肝細胞がんや肝芽腫に対する術後補助療法としてGPC3ペプチドワクチンはペプチド特異的CTL を誘導し、長期予後の延長に有望である2020
- Author(s)
  谷口理丈, 水野正一, 吉川聡明, 藤浪紀洋, 中面哲也
- Organizer
  第24回日本がん免疫学会
- Data Source
  KAKENHI-PROJECT-19K09297
[Presentation] HSP105由来ペプチドワクチンは投与患者において抗腫瘍免疫応答を惹起する：臨床第Ⅰ相試験の免疫モニタリング2020
- Author(s)
  清水康博、吉川聡明、下村真菜美、水野正一、和田聡、藤本祐希、小島隆嗣、遠藤格、中面哲也
- Organizer
  第17回日本免疫治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09297
[Presentation] 完全個別化がんペプチドワクチンの開発のためのネオアンチゲンの予測とその抗原性の評価2020
- Author(s)
  下村真菜美, 鈴木利宙, 藤浪紀洋, 平糠和志, 中島裕理, 吉川聡明, 佐々木諒子, 渡部典子, 山田崇, 松永宏美, 三嶋雄二, 中村徳弘, 中面哲也
- Organizer
  第24回日本がん免疫学会
- Data Source
  KAKENHI-PROJECT-19K09297
[Presentation] 早期ステージ固形癌において細胞傷害性T細胞への高い反応性を導くHLA class Iの高発現の証明2019
- Author(s)
  赤澤悠、信岡大輔、高橋真理、吉川聡明、下村真菜美、水野正一、中本安成、中面哲也
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09297
[Presentation] 難治性小児固形腫瘍に対するGPC3ペプチドワクチン療法の第Ⅰ相試験2018
- Author(s)
  清水康博、細野亜古、土屋伸広、吉川聡明、藤浪紀洋、齊藤桂吾、水野正一、中面哲也
- Organizer
  第15回日本免疫治療学研究会学術集会
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] 婦人科がんにおける個別化免疫療法の開発2018
- Author(s)
  野坂和外、吉川聡明、鈴木利宙、齊藤桂吾、下村真菜美、水野正一、鈴木史朗、吉川史隆、中面哲也
- Organizer
  第15回日本免疫治療学研究会学術集会
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] 肺がんに対する個別化免疫療法の開発を目指した自己腫瘍反応性TILの解析2018
- Author(s)
  吉川聡明、野坂和外、鈴木利宙、鈴木穣、関真秀、坂本裕美、市川仁、青景圭樹、坪井正博、中面哲也
- Organizer
  第15回日本免疫治療学研究会学術集会
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] 進行肝細胞がん患者に対するGlypican-3（GPC3）ペプチドワクチン療法の免疫学的効果2018
- Author(s)
  土屋伸広、吉川聡明、藤浪紀洋、齊藤桂吾、下村真菜美、野坂和外、清水康博、澤田雄、遠藤格、中面哲也
- Organizer
  第15回日本免疫治療学研究会学術集会
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] 肝細胞癌に対する術後補助療法としてのglypican-3ペプチドワクチン2018
- Author(s)
  谷口理丈、吉川聡明、鈴木利宙、赤澤悠、清水康博、土屋伸広、澤田雄、遠藤格、中面哲也
- Organizer
  第15回日本免疫治療学研究会学術集会
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] ヒト健常人・がん患者血液を用いたヒト化抗CD4抗体によるin vitroでのCD4陽性細胞への作用の検討2018
- Author(s)
  下村真菜美、北野滋久、正田香世子、吉川聡明、横地祥司、伊藤哲、松島綱治、植村靖史、中面哲也
- Organizer
  第15回日本免疫治療学研究会学術集会
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] 難治性小児固形腫瘍に対するGPC3ペプチドワクチン療法の第Ⅰ相試験2017
- Author(s)
  細野亜古、吉川聡明、藤浪紀洋、齊藤桂吾、水野正一、土屋伸広、木下義晶、孝橋賢一、中面哲也
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] 進行肝細胞がん患者に対するGlypican-3（GPC3）ペプチドワクチン療法の免疫学的効果2017
- Author(s)
  土屋伸広、吉川聡明、藤浪紀洋、齊藤桂吾、下村真菜美、鈴木利宙、野坂和外、清水康博、赤澤悠、Charneau Jimmy、澤田雄、遠藤格、中面哲也
- Organizer
  第21回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] 婦人科がんにおける複合免疫療法の開発2017
- Author(s)
  野坂和外、吉川聡明、鈴木利宙、齊藤桂吾、下村真菜美、水野正一、鈴木史朗、吉川史隆、中面哲也
- Organizer
  第30回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] Phase 1 study of HSP105‐derived peptide vaccine for patients with advanced esophageal cancer/ colo‐ rectal cancer.2017
- Author(s)
  Wada S, Kojima T, Nakatsura T, Bando H, Motohashi O, Shimomura M, Yoshikawa T, Kohashi K, Hori A, Ono H, Fukutani M, Wakabayashi M, Nomura S, Sato A, Sasada T, Ohtsu A.
- Organizer
  The European Society for Medical Oncology（ESMO）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] 肺がんに対する個別化免疫療法の開発を目指した腫瘍反応性CTL の同定と解析2017
- Author(s)
  吉川聡明、野坂和外、鈴木利宙、齊藤桂吾、下村真菜美、水野正一、鈴木穣、関真秀、坂本裕美、市川仁、青影圭樹、坪井正博、中面哲也
- Organizer
  第37回日本分子腫瘍マーカー研究会
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] Identification and analysis of tumor reactive CTLs in lung cancer tissues for developing a personalized immunotherapy.2017
- Author(s)
  Yoshikawa T,nosaka K, Suzuki T, Saito K, Shimomura M, Mizuno S, Suzuki Y, Seki M, Sakamoto H, Aoki K, Aokage K, Tsuboi M, Nakatsura T.
- Organizer
  第36回札幌国際がんシンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] 進行肝細胞癌患者に対するGlypican-3(GPC3)ペプチドワクチン療法の免疫学的効果2017
- Author(s)
  谷口理丈、土屋伸広、吉川聡明、藤浪紀洋、齊藤桂吾、水野正一、澤田雄、遠藤格、中面哲也
- Organizer
  第37回日本分子腫瘍マーカー研究会
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] 食道がん・大腸がん患者を対象としたHSP105由来ペプチドワクチンの第Ⅰ相医師主導治験2017
- Author(s)
  小島隆嗣、和田聡、中面哲也、坂東英明、本橋修、下村真菜美、吉川聡明、孝橋賢一、小野宏美、福谷美紀、若林将史、野村尚吾、佐藤暁洋、笹田哲朗、大津敦
- Organizer
  第55回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] 難治性小児固形腫瘍に対するGPC3ペプチドワクチン療法の第I相試験2017
- Author(s)
  細野亜古、土屋伸広、吉川聡明、藤浪紀洋、齊藤桂吾、水野正一、原純一、二谷千賀、真部淳、吉原宏樹、細谷要介、金田英秀、木下義晶、孝橋賢一、吉村健一、中面哲也
- Organizer
  第21回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] インターフェロンαを産生するiPS細胞由来増殖性ミエロイド細胞を用いたがん免疫療法の開発2017
- Author(s)
  土屋伸広、岩間達章、張エイ、得光友美、吉川聡明、澤田雄、田久保圭誉、遠藤格、中面哲也、植村靖史
- Organizer
  第16回日本再生医療学会総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] 肺がんに対する個別化免疫療法の開発を目指した腫瘍反応性CTLの解析2017
- Author(s)
  吉川聡明、野坂和外、鈴木利宙、齊藤桂吾、下村真菜美、水野正一、鈴木穣、関真秀、坂本裕美、青木一教、青景圭樹、坪井正博、中面哲也
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] glypican-3ペプチドワクチン療法の総括と展望2017
- Author(s)
  谷口理丈、吉川聡明、中面哲也
- Organizer
  第30回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] Immunological efficacy of glypican-3 (GPC3) peptide vaccine in patients with advanced hepatocellular carcinoma.2017
- Author(s)
  Tsuchiya N, Yoshikawa T, Fujinami K, Saito K, Shimomura M, Suzuki T, Nosaka K, Shimizu Y, Akazawa Y, Charneau J, Sawada Y, Endo I, Nakatsura T.
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] Phase I trial of glypican-3-derived peptide vaccine for refractory pediatric solid tumors.2017
- Author(s)
  Hosono A, Yoshikawa T, Fujinami N, Saito K, Mizuno S, Tsuchiya N, Hara J, Nitani C, Manabe A, Yoshihara H, Hosoya Y, Kaneda H, Kinoshita Y, Kohashi K, Yoshimura K, Nakatsura T.
- Organizer
  第36回札幌国際がんシンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] 肺がんに対する個別化腫瘍浸潤リンパ球療法の開発を目指した基礎検討2017
- Author(s)
  吉川聡明、野坂和外、鈴木利宙、齊藤桂吾、下村真菜美、水野正一、鈴木穣、関真秀、坂本裕美、吉田輝彦、青影圭樹、坪井正博、中面哲也
- Organizer
  第21回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] In vitroでのヒト化抗CD4抗体（IT1028）によるヒト血液検体中のCD4陽性細胞除去効果の検討2017
- Author(s)
  下村真菜美、北野滋久、正田香世子、吉川聡明、横地祥司、伊藤哲、松島綱治、植村靖史、中面哲也
- Organizer
  第14回日本免疫治療学研究会学術集会
- Place of Presentation
  東京大学伊藤国際学術研究センター（東京都文京区）
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] Immunological efficacy of glypican-3 (GPC3) peptide vaccine in patients with advanced hepatocellular carcinoma (HCC).2017
- Author(s)
  Tsuchiya N, Yoshikawa T, Fujinami N, Saito K, Shimomura M, Suzuki T, Nosaka K, Shimizu Y, Akazawa Y, Charneau J, Sawada Y, Endo I, Nakatsura T.
- Organizer
  第36回札幌国際がんシンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] Identification and analysis of tumor-reactive CTLs in ovarian and cervical cancer tissues for developing a personalized immunotherapy.2017
- Author(s)
  Nosaka K, Yoshikawa T, Suzuki T, Saito K, Shimomura M, Mizuno S, Suzuki S, Kikkawa F, Nakatsura T.
- Organizer
  Tumor Immunology and Immunotherapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] Phase I trial of glypican-3-derived peptide vaccine for refractory pediatric solid tumors.2017
- Author(s)
  Hosono A, Yoshikawa T, Tsuchiya N, Fujinami N, Saito K, Mizuno S, Nakatsura T.
- Organizer
  The European Society for Medical Oncology（ESMO）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] 選択的スプライシングによって生成する分泌型Gplypican-3 アイソフォームの同定2016
- Author(s)
  Saito K, Yoshikawa T, Saito Y, Fujinami N, Suzuki T, Jimmy C, Nakatsura T
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] ヒト血液検体を用いたヒト化抗CD4抗体によるIn VitroでのCD4陽性細胞除去効果の検討2016
- Author(s)
  下村真菜美、吉川聡明、正田香世子、岩上千鶴、齋藤友貴、野坂和外、水野正一、北野滋久、横地祥司、伊藤哲、松島綱治、植村靖史、中面哲也
- Organizer
  第20回日本がん免疫学会総会
- Place of Presentation
  大阪国際交流センター（大阪府大阪市）
- Year and Date
  2016-07-27
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] 抗CD4抗体併用によるがんペプチドワクチン療法の効果増強に関する前臨床的検討2016
- Author(s)
  藤浪紀洋、吉川聡明、澤田雄、下村真菜美、水野正一、北野滋久、植村靖史、中面哲也
- Organizer
  第20回日本がん免疫学会総会
- Place of Presentation
  大阪国際交流センター（大阪府大阪市）
- Year and Date
  2016-07-27
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] In vitroにおけるヒト化抗CD4抗体による末梢血中のCD4陽性細胞除去効果の検討2016
- Author(s)
  Shimomura M, Kitano S, Syoda K, Iwakami C, Saito Y, Nosaka K, Mizuno S,Yoshikawa T, Yokochi S, Matsushima K, Uemura Y, Nakatsura T.
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] IFNαを産生するiPSC由来増殖性ミエロイド細胞のがん治療への応用2016
- Author(s)
  Tsuchiya N, Uemura Y, Iwama T, Zhang R, Suzuki T, Yoshikawa T, Sawada Y, Takubo K, Sakaue-Sawano A, Miyawaki A, Endo I, Nakatsura T.
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] ヒト血液検体を用いたヒト化抗CD4抗体（IT1208）によるin vitroでのCD4陽性細胞除去の検討2016
- Author(s)
  下村真菜美、北野滋久、正田香世子、吉川聡明、横地祥司、伊藤哲、松島綱治、植村靖史、中面哲也
- Organizer
  第36回日本分子腫瘍マーカー研究会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] インターフェロンαを産生するiPS細胞由来増殖性ミエロイド細胞を用いたがん免疫療法2016
- Author(s)
  土屋伸広、植村靖史、岩間達章、張エイ、得光友美、鈴木利宙、吉川聡明、澤田雄、田久保圭誉、阪上-沢野朝子、宮脇敦史、千住覚、遠藤格、中面哲也
- Organizer
  第20回日本がん免疫学会総会
- Place of Presentation
  大阪国際交流センター（大阪府大阪市）
- Year and Date
  2016-07-27
- Data Source
  KAKENHI-PROJECT-16K19990
[Presentation] GPC3 expression could be the biomarker of the GPC3-derived peptide vaccine as an adjuvant therapy for hepatocellular carcinoma patients: Results from phase II trial.2015
- Author(s)
  Sawada Y, Yoshikawa T, Ofuji K, Yoshimura M, Tsuchiya N, Endo I, Nakatsura T.
- Organizer
  がん免疫療法・マクロファージ国際会議2015
- Place of Presentation
  東京
- Year and Date
  2015-07-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861133
[Presentation] The enhancement of the antitumor effect by peptide vaccine therapy in combination with anti-CD4 antibody:Study in murine model2015
- Author(s)
  Fujinami N, Yoshikawa T, Sawada Y, Shimomura M, Uemura Y, Nakatsura T.
- Organizer
  第44回日本免疫学会総会・学術集会
- Place of Presentation
  札幌市
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-26861133
[Presentation] GPC3ペプチドワクチンを用いた肝細胞がん根治的治療後補助療法の臨床第II相試験におけるバイオマーカー探索2015
- Author(s)
  中面哲也、澤田雄、吉川聡明、髙橋真理、大藤和也、吉村麻友子
- Organizer
  第35回日本分子腫瘍マーカー研究会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-07
- Data Source
  KAKENHI-PROJECT-26861133
[Presentation] Glypican-3（GPC3）ペプチドワクチン投与後の投与局所及び腫瘍局所でのペプチド特異的CTL の解析2015
- Author(s)
  吉川聡明、下村真菜美、澤田雄、高橋真理、植村靖史、中面哲也
- Organizer
  第12回日本免疫治療学研究会学術集会
- Place of Presentation
  東京ガーデンパレス　東京都
- Year and Date
  2015-02-28
- Data Source
  KAKENHI-PROJECT-26861133
[Presentation] マウスモデルを用いた抗CD4抗体投与併用によるがんペプチドワクチン療法の効果増強の検討2015
- Author(s)
  藤浪紀洋、吉川聡明、澤田雄、下村真菜美、植村靖史、中面哲也
- Organizer
  第28回日本バイオセラピィ学会
- Place of Presentation
  川越
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-26861133
[Presentation] Regulation of IL-12 family cytokine/Osteopontin balance in DCs by ligand activation of iNKT cells.2015
- Author(s)
  Iwama T, Suzuki M, Liu T, Zhang R, Yoshikawa T, Shimomura M, Nakatsura T, Kuzushima K, Uemura Y.
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26861133
[Presentation] Phase II study of the GPC3-derived peptide vaccine as an adjuvant therapy for hepatocellular carcinoma patients.2015
- Author(s)
  Sawada Y,Yoshikawa T, Ofuji K, Yoshimura M, Tsuchiya N, Takahashi M, Nobuoka D, Mizuno S, Endo I, Nakatsura T.
- Organizer
  AACR 106th　Annual Meeting 2015
- Place of Presentation
  アメリカ
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861133
[Presentation] Phase II trial of the GPC3-derived peptide vaccine as an adjuvant therapy for hepatocellular carcinoma patients.2015
- Author(s)
  Sawada Y, Yoshikawa T, Ofuji K, Yoshimura M, Tsuchiya N, Endo I, Nakatsura T.
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26861133
[Presentation] Phase I study of vaccine therapy with a cocktail of peptides for pediatric patients with refractory solid tumors.2015
- Author(s)
  Hosono A, Kaneda H, Hara J, Nitani C, Yoshikawa T, Kohashi K, Nakatsura T.
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26861133
[Presentation] Vaccination of GPC3-derived peptide-coupled liposome inhibits GPC3 expressing tumor growth.2015
- Author(s)
  Tsuchiya N, Iwama T, Uchida T, Shimomura M, Yoshikawa T, Fujinami N, Saito Y, Uemura Y, Nakatsura T.
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26861133
[Presentation] HLA class I expression in a tumor is higher than that out of a tumor: Promising new findings for antigen-specific cancer immunotherapy.2015
- Author(s)
  Nobuoka D, Takahashi M, Yoshikawa T, Yagi T, Fujiwara T, Nakatsura T.
- Organizer
  AACR 106th　Annual Meeting 2015
- Place of Presentation
  アメリカ
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861133
[Presentation] マウスモデルを用いた抗CD4抗体併用によるがんペプチドワクチン療法の効果増強の検討2015
- Author(s)
  藤浪紀洋、吉川聡明、澤田雄、下村真菜美、植村靖史、中面哲也
- Organizer
  第43回日本臨床免疫学会総会
- Place of Presentation
  神戸
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-26861133
[Presentation] HLA class I expression in and out of a tumor: Promising new findings for antigen-specific cancer immunotherapy.2015
- Author(s)
  Nobuoka D, Takahashi M, Yoshikawa T, Yagi T, Fujiwara T, Nakatsura T.
- Organizer
  がん免疫療法・マクロファージ国際会議2015
- Place of Presentation
  東京
- Year and Date
  2015-07-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861133
[Presentation] Phase I study of vaccine therapy with a cocktail of peptides for pediatric patients with refractory solid tumors.2015
- Author(s)
  Hosono A, Kaneda H, Hara J, Nitani C, Kohashi K, Manabe A, Yoshikawa T, Nakatsura T.
- Organizer
  がん免疫療法・マクロファージ国際会議2015
- Place of Presentation
  東京
- Year and Date
  2015-07-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861133
[Presentation] Efficient crosspresentation of oncofetal antigen (Glypican-3)-derived long peptides encompassing CTL and promiscuous Th cell epitopes using a novel liposome.2015
- Author(s)
  Mohammad A.S, Tomita Y, Yuno A, Hirayama M, Irie A, Tsukamoto H, Senju S, Yuba E, Yoshikawa T, Kono K, Nakatsura T, Nishimura Y.
- Organizer
  AACR 106th　Annual Meeting 2015
- Place of Presentation
  アメリカ
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861133
[Presentation] ヒト健常人・がん患者血液を用いたヒト化抗CD4 抗体（IT1208）によるin vitro でのCD4 陽性細胞除去の検証2015
- Author(s)
  下村真菜美、正田香世子、吉川聡明、須貝詩織、北野滋久、横地祥司、伊藤哲、松島綱治、植村靖史、中面哲也
- Organizer
  第35回日本分子腫瘍マーカー研究会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-07
- Data Source
  KAKENHI-PROJECT-26861133
[Presentation] EGFR T790M mutation-derived antigen provides the immunogenicity in NSCLC patients.
- Author(s)
  大藤和也、吉川聡明、多田好孝、吉村麻友子、下村真菜美、中本安成、中面哲也
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜　横浜市
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26861133
[Presentation] Analysis of glypican-3 specific CTLs in the tumor tissue and vaccination site after administration of GPC3 peptide.
- Author(s)
  吉川聡明、下村真菜美、澤田　雄、植村靖史、中面哲也
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜　横浜市
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26861133
[Presentation] がんペプチドワクチン後予後予測マーカーとしての治療前血中IL6・IL8 の意義
- Author(s)
  藤田知信、野路しのぶ、南雲春奈、岡本正人、桜井敏晴、澤田雄、吉川聡明、下村真菜美、中面哲也、野口正典、松枝智子、伊東恭悟、硲彰一、竹之内寛子、岡正典、河上裕
- Organizer
  第18回日本がん免疫学会総会
- Place of Presentation
  ひめぎんホール　松山市
- Year and Date
  2014-07-30 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-26861133
[Presentation] Glypican-3由来エピトープペプチド結合リポソームのCTL誘導能の評価
- Author(s)
  岩間達章、内田哲也、下村真菜美、吉川聡明、中面哲也
- Organizer
  第18回日本がん免疫学会総会
- Place of Presentation
  ひめぎんホール　松山市
- Year and Date
  2014-07-30 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-26861133
[Presentation] The enhancement of the CTL induction by peptide vaccine therapyin combinatio n with anti-CD4 antibody
- Author(s)
  藤浪紀洋、吉川聡明、澤田雄、下村真菜美、岩間達章、植村靖史、中面哲也
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜　横浜市
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26861133
[Presentation] Evaluation of peptide-specific CTL-inducible ability of glypican-3-derived p eptide-coupled liposome vaccine.
- Author(s)
  岩間達章、内田哲也、下村真菜美、吉川聡明、中面哲也
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜　横浜市
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26861133
[Presentation] Glypican-3(GPC3) ペプチドワクチン投与後の投与局所及び腫瘍局所でのペプチド特異的CTLの解析
- Author(s)
  吉川聡明、下村真菜美、澤田雄、高橋真理、吉原宏樹、上野浩生、真部淳、細野亜古、植村靖史、中面哲也
- Organizer
  第18回日本がん免疫学会総会
- Place of Presentation
  ひめぎんホール　松山市
- Year and Date
  2014-07-30 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-26861133
[]

1. 岩間達章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 中本安成

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. 植村靖史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 張エイ

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 木下義晶

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yoshikawa Toshiaki 吉川 聡明

吉川 聡明 ヨシカワ トシアキ

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腫瘍反応性T細胞の濃縮と機能改善に基づく婦人科がん個別化T細胞療法の新規開発Principal Investigator

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Developing a personalized immunotherapy: Identification of tumor reactive CTLsPrincipal Investigator

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Developing a personalized immunotherapy for lung cancer patients: Identification of tumor reactive CTLsPrincipal Investigator

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Development of adoptive T cell therapy for lung cancer that have complicated mutationsPrincipal Investigator

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[Book] Development of glypican-3-targeted cancer immunotherapy.2015

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[Journal Article] Development of a chimeric cytokine receptor that captures IL-6 and enhances the antitumor response of CAR-T cells2024

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[Journal Article] Aberrant splicing isoforms detected by full-length transcriptome sequencing as transcripts of potential neoantigens in non-small cell lung cancer.2021

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[Journal Article] Peptide vaccine as an adjuvant therapy for glypican-3 positive hepatocellular carcinoma induces peptide specific CTLs and improves long prognosis.2020

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[Journal Article] Efficacy of immunotherapy targeting the neoantigen derived from EGFR T790M/C797S mutation in non-small cell lung cancer.2020

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[Journal Article] Tumor-infiltrating T cells concurrently overexpress CD200R with immune checkpoints PD-1, CTLA-4 and TIM-3 in non-small cell lung cancer.2020

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[Journal Article] Efficacy of the NCCV Cocktail‐1 vaccine for refractory pediatric solid tumors: A phase I clinical trial2019

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[Journal Article] Heat shock protein 105 peptide vaccine could induce antitumor immune reactions in a phase I clinical trial2019

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[Journal Article] Cancer Immunotherapy Targeted Glypican-3 or Neoantigens.2018

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[Journal Article] Perioperative plasma glypican-3 level may enable prediction of the risk of recurrence after surgery in patients with stage I hepatocellular carcinoma.2017

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[Journal Article] Phase I study of glypican-3-derived peptide vaccine therapy for patients with refractory pediatric solid tumors2017

Yoshikawa Toshiaki 吉川聡明

吉川聡明ヨシカワトシアキ

[Journal Article] Tumor-infiltrating T cells concurrently overexpress CD200R with immune checkpoints PD-1, CTLA-4 and TIM-3 in　non-small cell lung cancer.2020