Shimizu Saki 清水佐紀

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SHIMIZU SAKI 清水佐紀

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Researcher Number	00630815
Other IDs
Affiliation (Current)	2025: 大阪医科薬科大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 大阪医科薬科大学, 薬学部, 准教授 2016 – 2020: 大阪薬科大学, 薬学部, 助教 2016: 大阪薬科大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 47040:Pharmacology-related / General pharmacology Except Principal Investigator Basic Section 47040:Pharmacology-related / Pharmacology in pharmacy
Keywords	Principal Investigator 行動薬理学 / Fosタンパク / 神経化学 / てんかん原性 / pentylenetetrazole / 脳内アミノ酸 / 4-aminopyridine / 電撃けいれん / Pilocarpine誘発けいれん重積発作 / 扁桃核 … More / 大脳皮質運動野 / けいれん発現 / てんかん / HCN1チャネル / 脳神経疾患 / 神経科学 / 薬理学 / 動物モデル / β受容体遮断薬 / セロトニン代謝回転 / 下オリーブ核 / セロトニン（5-HT） / 脳内モノアミン / aspartoacylase / β遮断薬 / 本態性振戦 … More Except Principal Investigator てんかん / 不安障害 / けいれん発作 / うつ病 / 神経疾患 / 精神疾患 / 認知機能障害 / 抑うつ・不安障害 / 空間的カリウム緩衝機構 / 内向き整流性Kir4.1チャネル / アストロサイト / 動物モデル / シナプス小胞蛋白2A (SV2A) / グルタミン酸 / 開口分泌 / シナプス小胞タンパク2A　（SV2A) / シナプス / 大脳辺縁系 / GABA / 神経伝達物質 / キンドリング / てんかん原性 / シナプトタグミン１ / GABA遊離 / シナプス小胞蛋白SV2A / シナプス分泌 Less

Analysis of the mechanisms underlying development of neuropsychiatric diseases with focus on astrocytic potassium buffering function
- Principal Investigator
  
  Ohno Yukihiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Analysis of the modulation mechanism in induction of epileptic seizure via hyperpolarization activated cyclic nucleotide-gated (HCN) channel 1Principal Investigator
- Principal Investigator
  
  Shimizu Saki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Osaka Medical and Pharmaceutical University
  Osaka University of Pharmaceutical Sciences
Pathophysiological analysis of essential tremor and identification of the novel therapeutic targets.Principal Investigator
- Principal Investigator
  
  Shimizu Saki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Osaka University of Pharmaceutical Sciences
Pathophysiological analysis of epilepsy with focusing on the synaptic release mechanism
- Principal Investigator
  
  Yukihiro Ohno
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Osaka University of Pharmaceutical Sciences

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 Other

All Journal Article Presentation Book

[Book] In Vivo Neuropharmacology and Neurophysiology2016
- Author(s)
  H.A. Iha, N. Kunisawa, K. Tokudome, T. Mukai, M. Kinboshi,　S. Shimizu, Y. Ohno
- Publisher
  Springer Science+Business Media, LLC, New York
- Data Source
  KAKENHI-PROJECT-26460111
[Journal Article] Mechanisms Underlying Dopaminergic Regulation of Nicotine-Induced Kinetic Tremor2022
- Author(s)
  Masaki Kato, Naofumi Kunisawa, Saki Shimizu, Higor A. Iha, Yukihiro Ohno
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 13 Pages: 938175-938175
- DOI
  10.3389/fphar.2022.938175
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06587, KAKENHI-PROJECT-21K15278
[Journal Article] Emerging Roles of Astrocyte Kir4.1 Channels in the Pathogenesis and Treatment of Brain Diseases.2021
- Author(s)
  Y. Ohno, N. Kunisawa, S. Shimizu
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 22 Issue: 19 Pages: 10236-10236
- DOI
  10.3390/ijms221910236
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16384, KAKENHI-PROJECT-21K06587, KAKENHI-PROJECT-21K15278
[Journal Article] Involvement of NMDA receptors in tremor expression in <i>Aspa</i>/<i>Hcn1</i> double-knockout rats2020
- Author(s)
  A. Nishitani, H. Nagayoshi, S. Takenaka, M. Asano, S. Shimizu, Y. Ohno, T. Kuramoto
- Journal Title
  
  Exp. Anim.
  
  Volume: 69 Issue: 4 Pages: 388-394
- DOI
  10.1538/expanim.20-0025
- NAID
  130007938669
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16384
[Journal Article] Mechanism Underlying Organophosphate Paraoxon-Induced Kinetic Tremor.2019
- Author(s)
  Iha HA, Kunisawa N, Shimizu S, Onishi M, Nomura Y, Matsubara N, Iwai C, Ogawa M, Hashimura M, Sato K, Kato M, Ohno Y.
- Journal Title
  
  Neurotox Res.
  
  Volume: 35 Issue: 3 Pages: 575-583
- DOI
  10.1007/s12640-019-0007-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K21501, KAKENHI-PROJECT-17K08324
[Journal Article] Down-Regulation of Astrocytic Kir4.1 Channels during the Audiogenic Epileptogenesis in Leucine-Rich Glioma-Inactivated 1 (Lgi1) Mutant Rats.2019
- Author(s)
  Masato Kinboshi , Saki Shimizu, Tomoji Mashimo, Tadao Serikawa, Hidefumi Ito, Akio Ikeda, Ryosuke Takahashi, Yukihiro Ohno
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 5 Pages: 001-015
- DOI
  10.3390/ijms20051013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-INTERNATIONAL-15K21731, KAKENHI-ORGANIZER-15H05871, KAKENHI-PLANNED-15H05874, KAKENHI-PROJECT-16K21501, KAKENHI-PROJECT-17K08324, KAKENHI-PROJECT-18H03974, KAKENHI-PROJECT-19H03574
[Journal Article] Pharmacological characterization of nicotine-induced tremor: Responses to anti-tremor and anti-epileptic agents.2018
- Author(s)
  N. Kunisawa, S. Shimizu, M. Kato, H. A. Iha, C. Iwai, M. Hashimura, M. Ogawa, S. Kawaji, K. Kawakita, K. Abe, Y. Ohno
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 137 Issue: 2 Pages: 162-169
- DOI
  10.1016/j.jphs.2018.05.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08324, KAKENHI-PROJECT-16K21501
[Journal Article] Inwardly rectifying potassium channel Kir4.1 as a novel modulator of BDNF expression in astrocytes.2018
- Author(s)
  Y. Ohno, M. Kinboshi, S. Shimizu
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 19 Issue: 11 Pages: 3313-3313
- DOI
  10.3390/ijms19113313
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08324, KAKENHI-PROJECT-16K21501
[Journal Article] Glycine-Binding Site Stimulants of NMDA Receptors Alleviate Extrapyramidal Motor Disorders by Activating the Nigrostriatal Dopaminergic Pathway2017
- Author(s)
  Saki Shimizu、Shunsaku Sogabe、Ryoto Yanagisako、Akiyoshi Inada、Megumi Yamanaka、Higor Iha、Yukihiro Ohno
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 18 Issue: 7 Pages: 1416-1416
- DOI
  10.3390/ijms18071416
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K21501
[Journal Article] Serotonergic modulation of nicotine-induced kinetic tremor in mice2017
- Author(s)
  Kunisawa Naofumi、Iha Higor A.、Nomura Yuji、Onishi Misaki、Matsubara Nami、Shimizu Saki、Ohno Yukihiro
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 134 Issue: 2 Pages: 131-138
- DOI
  10.1016/j.jphs.2017.06.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08324, KAKENHI-PROJECT-16K21501
[Journal Article] Inhibition of Inwardly Rectifying Potassium (Kir) 4.1 Channels Facilitates Brain-Derived Neurotrophic Factor (BDNF) Expression in Astrocytes2017
- Author(s)
  Kinboshi Masato、Mukai Takahiro、Nagao Yuki、Matsuba Yusuke、Tsuji Yoshimi、Tanaka Shiho、Tokudome Kentaro、Shimizu Saki、Ito Hidefumi、Ikeda Akio、Inanobe Atsushi、Kurachi Yoshihisa、Inoue Seiji、Ohno Yukihiro
- Journal Title
  
  Frontiers in Molecular Neuroscience
  
  Volume: 10 Pages: 408-408
- DOI
  10.3389/fnmol.2017.00408
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08324, KAKENHI-PROJECT-16K21501, KAKENHI-INTERNATIONAL-15K21731, KAKENHI-ORGANIZER-15H05871, KAKENHI-PLANNED-15H05874, KAKENHI-PROJECT-15H04270, KAKENHI-PROJECT-15K09351, KAKENHI-PROJECT-17H04018
[Journal Article] Nicotine elicits convulsive seizures by activating amygdalar neurons.2017
- Author(s)
  Iha HA, Kunisawa N, Shimizu S, Tokudome K, Mukai T, Kinboshi M, Ikeda A, Ito H, Serikawa T, Ohno Y
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 8 Pages: 57-57
- DOI
  10.3389/fphar.2017.00057
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-15H05871, KAKENHI-PLANNED-15H05874, KAKENHI-PROJECT-15H04270, KAKENHI-PROJECT-26293209, KAKENHI-PROJECT-26460111, KAKENHI-PROJECT-16K21501, KAKENHI-INTERNATIONAL-15K21731
[Journal Article] Tremor dominant Kyoto ( Trdk ) rats carry a missense mutation in the gene encoding the SK2 subunit of small-conductance Ca 2+ -activated K + channel2017
- Author(s)
  Kuramoto Takashi、Yokoe Mayuko、Kunisawa Naofumi、Ohashi Kana、Miyake Takahito、Higuchi Yuki、Yoshimi Kazuto、Mashimo Tomoji、Tanaka Miyuu、Kuwamura Mitusru、Kaneko Shuji、Shimizu Saki、Serikawa Tadao、Ohno Yukihiro
- Journal Title
  
  Brain Research
  
  Volume: 1676 Pages: 38-45
- DOI
  10.1016/j.brainres.2017.09.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K21501, KAKENHI-PROJECT-26290033
[Journal Article] Nicotine evokes kinetic tremor by activating the inferior olive via α7 nicotinic acetylcholine receptors.2016
- Author(s)
  N. Kunisawa, H. A. Iha, S. Shimizu, K. Tokudome, T. Mukai, M. Kinboshi, T. Serikawa, Y. Ohno: Nicotine evokes kinetic tremor by activating the inferior olive via α7 nicotinic acetyl
- Journal Title
  
  Behav. Brain Res.
  
  Volume: 314 Pages: 173-180
- DOI
  10.1016/j.bbr.2016.08.013
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460111, KAKENHI-PROJECT-16K21501
[Journal Article] Immunohistochemical analysis of Fos protein expression for exploring brain regions related to central nervous system disorders and drug actions.2016
- Author(s)
  H.A. Iha, N. Kunisawa, K. Tokudome, T. Mukai, M. Kinboshi,　S. Shimizu, Y. Ohno
- Journal Title
  
  Neuromethods
  
  Volume: 121 Pages: 389-408
- DOI
  10.1007/978-1-4939-6490-1_17
- ISBN
  9781493964888, 9781493964901
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460111, KAKENHI-PROJECT-16K21501
[Journal Article] Synaptic vesicle glycoprotein 2A (SV2A) regulates kindling epileptogenesis via GABAergic neurotransmission.2016
- Author(s)
  Tokudome K, Okumura T, Shimizu S, Mashimo T, Takizawa A, Serikawa T, Terada R, Ishihara S, Kunisawa N, Sasa M, Ohno Y.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 2742-2742
- DOI
  10.1038/srep27420
- NAID
  120006349333
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26290033, KAKENHI-PROJECT-26460111
[Journal Article] A Missense Mutation of the Gene Encoding Synaptic Vesicle Glycoprotein 2A (SV2A) Confers Seizure Susceptibility by Disrupting Amygdalar Synaptic GABA Release.2016
- Author(s)
  Tokudome K, Okumura T, Terada R, Shimizu S, Kunisawa N, Mashimo T, Serikawa T, Sasa M, Ohno Y.
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 7 Pages: 210-210
- DOI
  10.3389/fphar.2016.00210
- NAID
  120006331984
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26290033, KAKENHI-PROJECT-26460111
[Journal Article] Involvement of aspartoacylase in tremor expression in rats2016
- Author(s)
  A. Nishitani, M. Tanaka, S. Shimizu, N. Kunisawa, M. Yokoe, Y. Yoshida, T. Suzuki, T. Sakuma, T. Yamamoto, M. Kuwamura, S. Takenaka, Y. Ohno, T. Kuramoto
- Journal Title
  
  Exp. Anim.
  
  Volume: 65 Issue: 3 Pages: 293-301
- DOI
  10.1538/expanim.16-0007
- NAID
  130006882372
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K21501
[Journal Article] New insight into the therapeutic role of the serotonergic system in Parkinson’s disease2015
- Author(s)
  Y. Ohno, S. Shimizu, K. Tokudome, N. Kunisawa, M. Sasa
- Journal Title
  
  Progress in Neurobiology
  
  Volume: 134 Pages: 104-121
- DOI
  10.1016/j.pneurobio.2015.09.005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Kir4.1チャネル阻害薬quinacrineの抗うつ効果におけるアストロサイトの関与2024
- Author(s)
  日下綾菜、石﨑悠斗、井上莉歩、楠野将也、清水佐紀、大野行弘
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] フルオロクエン酸によるアストロサイトの不活性化がペンチレンテトラゾール誘発けいれんに及ぼす影響2024
- Author(s)
  國澤直史、清水佐紀、大野行弘
- Organizer
  第144回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] Kir4.1チャネル阻害薬quinacrineの神経炎症を伴う認知機能障害に対する改善作用2024
- Author(s)
  石崎悠斗、清水佐紀、妹尾帆夏、田原拓真、大野行弘
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] 抗LGI1抗体の海馬内投与マウスにおけるけいれん感受性の評価2023
- Author(s)
  菊池絵理、清水佐紀、石崎悠斗、高橋良輔、池田昭夫、大野行弘
- Organizer
  第53回臨床神経生理学会学術大会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] ニコチンによる運動興奮症状発現におけるアストロサイト活性化の役割2023
- Author(s)
  河田千佳、國澤直史、後藤光佑、江原澪、清水佐紀、大野行弘
- Organizer
  第73回日本薬学会関西支部総会・大会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] Effects of the intrahippocampal injection of anti-Lgi1 antibody on cognitive function and seizure susceptibility in mice2023
- Author(s)
  Eri Kikuchi,, Saki Shimizu, Yuto Ishizaki, Akihiro Shimotake, Kiyohide Usami, Masao Matsuhashi, Ryosuke Takahashi, Akio Ikeda, Yukihiro Ohno
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] コルチコステロン慢性投与マウスのうつ様症状に対するKir4.1チャネル阻害薬の作用評価2023
- Author(s)
  清水佐紀、堀名宏紀、中野諒子、廣瀬由佳、大野行弘
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] ニコチンによる運動興奮症状の発現におけるアストロサイトの関与2023
- Author(s)
  國澤直史、江原澪、河田千佳、後藤光佑、清水佐紀、大野行弘
- Organizer
  第143回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] ニコチンによる運動興奮症状に対するアストロサイト選択的抑制剤フルオロクエン酸の影響2023
- Author(s)
  國澤直史、加藤将貴、小田明奈、白川美波、坂口茉鈴、清水佐紀、大野行弘
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] フルオロクエン酸投与によるアストロサイト不活性化モデルの作成2023
- Author(s)
  後藤光佑、國澤直史、河田千佳、江原澪、清水佐紀、大野行弘
- Organizer
  第73回日本薬学会関西支部総会・大会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] Effects of the Kir4.1 blocker, quinacrine,　on lipopolysaccharide-induced cognitive impairment2023
- Author(s)
  Yuto Ishizaki, Saki Shimizu, Honatsu Seo, Takuma Tahara, Yukihiro Ohno
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] アストロサイト選択的抑制剤フルオロクエン酸の内向き整流性Kir4.1チャネル発現およびペンチレンテトラゾールけいれん感受性に対する作用評価2022
- Author(s)
  國澤直史、加藤将貴、髙田和志、豊桝美沙、藤原安哉子、清水佐紀、大野行弘
- Organizer
  日本薬学会第142回年会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] Lipopolysaccharideによる神経炎症性アルツハイマー病モデルの確立2022
- Author(s)
  毎田愛莉、清水佐紀、石﨑悠斗、森山芽衣、宮越樹里、佐納　匠、大野行弘
- Organizer
  第72回日本薬学会関西支部総会・大会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] Kir4.1チャネル遮断薬quinacrineによる急性うつ病モデルマウスを用いた抗うつ効果の評価2022
- Author(s)
  清水佐紀、中村義弘、日垣愛生、東野いずみ、石﨑悠斗、大野行弘
- Organizer
  日本薬学会第142回年会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] Evaluation of the effects of Kir4.1 channel inhibitors on lipopolysaccharide-induced depressive behavior2022
- Author(s)
  Saki Shimizu, Ryoko Nakano, Yuka Hirose, Kouki Horina, Yukihiro Ohno
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] Pentylenetetrazole誘発けいれんに対するアストロサイト選択的阻害剤フルオロクエン酸の影響2022
- Author(s)
  國澤直史、加藤将貴、髙田和志、豊桝美沙、藤原安哉子、清水佐紀、大野行弘
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] Lipopolysaccharide誘発急性うつ症状に対するKir4.1チャネル阻害薬の作用評価2022
- Author(s)
  廣瀬由佳、中野諒子、堀名宏紀、清水佐紀、大野行弘
- Organizer
  第72回日本薬学会関西支部総会・大会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] ニコチンによる運動興奮症状におけるアストロサイトの関与2022
- Author(s)
  國澤直史、加藤将貴、小田明奈、白川美波、坂口茉鈴、清水佐紀、大野行弘
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] 強制水泳試験を用いた内向き整流性カリウムチャネルKir4.1阻害薬の抗うつ作用評価2021
- Author(s)
  清水佐紀、日垣愛生、中村義弘、東野いずみ、石﨑悠斗、大野行弘
- Organizer
  第71回日本薬学会関西支部総会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] Enhanced sensitivity of epileptic seizure by deficit of hyperpolarization activated cyclic nucleotide-gated (HCN) channel 12021
- Author(s)
  Saki Shimizu, Yuto Ishizaki, Tatsuya Hattori, Yuki Kotaru, Sara Mishio, Airi Maida, Mei Moriyama, Takumi Sano, Juri Miyakoshi, Takashi Kuramoto, Yukihiro Ohno
- Organizer
  第95回日本薬学会年会
- Data Source
  KAKENHI-PROJECT-19K16384
[Presentation] マウス強制水泳試験を用いたKir4.1チャネル阻害薬による抗うつ効果の評価2021
- Author(s)
  日垣愛生、中村義弘、東野いずみ、石﨑悠斗、清水佐紀、大野行弘
- Organizer
  生体機能と創薬シンポジウム
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] 過分極活性化環状ヌクレオチド依存性HCN1チャネル欠損ラットにおけるけいれん感受性評価2021
- Author(s)
  石﨑悠斗、清水佐紀、服部達矢、小垂祐貴、三塩沙羅、庫本高志、大野行弘
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19K16384
[Presentation] セロトニン神経系を介したアストロサイト内向き整流性Kir4.1チャネルの発現調節機構2020
- Author(s)
  清水佐紀、古居薫、加藤綾、澤島愛加梨、池田昭夫、大野行弘
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K16384
[Presentation] Serotonergic regulation of the inwardly rectifying potassium (Kir) 4.1 channel expression in mice astrocytes.2020
- Author(s)
  Saki Shimizu, Kaoru Furui, Aya Kato, Akari Sawashima, Akio Ikeda, Yukihiro Ohno
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K16384
[Presentation] Muscarinic acetylcholine receptors regulate the expression of Kir4.1 channels and brain-derived neurotrophic factor (BDNF) in cultured mouse astrocytes.2019
- Author(s)
  Saki Shimizu, Masato Kinboshi, Yukako Nakamura, Nishiki Oda, Akio Ikeda, Yukihiro Ohno
- Organizer
  2019 International society of neurochemistry (ISN)-American society of neurochemistry (ASN) Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16384
[Presentation] Enhancement of 5-HT synthesis and metabolism in aspartoacylase-knockout rats.2019
- Author(s)
  Kasumi Maekawa, Saki Shimizu, Shinichiro Masuda, Yukie Oguru, Nana Katsumi, Keisuke Abe, Ai Nishitani, Takashi Kuramoto, Yukihiro Ohno
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-16K21501
[Presentation] Mechanism of organophosphate paraoxon-induced kinetic tremor in mice.2019
- Author(s)
  Yukihiro Ohno, Chihiro Iwai, Iha Higor. A, Naofumi Kunisawa, Saki Shimizu, Masaki Kato, Mizuki Ogawa, Mai Hashimura
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-16K21501
[Presentation] Harmaline誘発振戦に対するセロトニン神経系の制御機構2019
- Author(s)
  前川華澄、塚本弥恵、山中美生、井上裕太、清水佐紀、大野行弘
- Organizer
  生体機能と創薬シンポジウム2019
- Data Source
  KAKENHI-PROJECT-19K16384
[Presentation] アスパルトアシラーゼ遺伝子欠損ラットにおける下オリーブ核のセロトニン合成および代謝回転の亢進作用2019
- Author(s)
  清水佐紀、升田晋一朗、尾来雪絵、勝見菜奈、阿部圭佑、西谷あい、庫本高志、大野行弘
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16K21501
[Presentation] セロトニン神経系を介したharmaline誘発振戦の発現調節機構2019
- Author(s)
  山中美生、塚本弥恵、前川華澄、井上裕太、清水佐紀、大野行弘
- Organizer
  第69回日本薬学会関西支部総会・大会
- Data Source
  KAKENHI-PROJECT-19K16384
[Presentation] Acetylcholinergic regulation of astrocytic Kir4.1 and brain-derived neurotrophic factor (BDNF) expression in mice.2019
- Author(s)
  Saki Shimizu, Masato Kinboshi, Yukako Nakamura, Nishiki Oda, Akio Ikeda, Yukihiro Ohno
- Organizer
  第42回日本神経科学学会
- Data Source
  KAKENHI-PROJECT-19K16384
[Presentation] Aspartoacylase遺伝子欠損ラットにおける脳内モノアミン含量の解析2018
- Author(s)
  升田晋一朗、阿部圭佑、尾来雪絵、勝見菜奈、清水佐紀、大野行弘
- Organizer
  第68回日本薬学会近畿支部総会・大会
- Data Source
  KAKENHI-PROJECT-16K21501
[Presentation] 抗精神病薬による錐体外路障害の発現予測とセロトニン神経に着目した回避法検討2018
- Author(s)
  清水佐紀、多田羅絢加、水口裕登、安達咲希、木津朋也、祖父江顕、藤原麻衣、森本朋樹、大野行弘
- Organizer
  生体機能と創薬シンポジウム2018
- Data Source
  KAKENHI-PROJECT-16K21501
[Presentation] ニコチン誘発振戦の薬理解析：抗振戦薬および抗てんかん薬に対する反応性評価2018
- Author(s)
  加藤将貴、國澤直史、清水佐紀、岩井千紘、小川瑞葵、橋村舞、河合悦子、大野行弘
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K21501
[Presentation] ニコチン誘発振戦の薬理解析：抗振戦薬および抗てんかん薬に対する反応性評価2018
- Author(s)
  加藤将貴、國澤直史、清水佐紀、Higor Alves Iha、岩井千紘、橋村　舞、小川瑞葵、川路翔平、河北和馬、阿部圭佑、大野行弘
- Organizer
  第133回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16K21501
[Presentation] Serotonergic modulation of nicotine-induced tremor.2017
- Author(s)
  Naofumi Kunisawa, Higor A. Iha, Misaki Onishi, Yuji Nomura, Nami Matsubara, Saki Shimizu, Yukihiro Ohno
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-16K21501
[Presentation] NMDA受容体グリシン結合部位活性化薬は黒質－線条体ドパミン神経路の活性化を介して錐体外路障害を改善する2017
- Author(s)
  清水佐紀、曽我部俊策、柳迫領仁、稲田顕慶、山中萌、大野行弘
- Organizer
  第39回日本生物学的精神医学会・第47回日本神経精神薬理学会合同年会
- Data Source
  KAKENHI-PROJECT-16K21501
[Presentation] Glycine-binding site agonists of NMDA receptors alleviate extrapyramidal side effects by activating nigrostriatal dopamine pathway.2017
- Author(s)
  Saki Shimizu, Shunsaku Sogabe, Ryoto Yanagisako, Akiyoshi Inada, Megumi Yamanaka, Yukihiro Ohno
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-16K21501
[Presentation] パラオキソンによる振戦発現のメカニズム解析2017
- Author(s)
  國澤直史、Higor A. Iha、清水佐紀、尾西美咲、野村有治、松原菜美、岩井千紘、小川瑞葵、橋村舞、河合悦子、大野行弘
- Organizer
  第44回日本毒性学会学術集会
- Data Source
  KAKENHI-PROJECT-16K21501
[Presentation] Effects of D-cycloserine, a glycine-binding site agonist of NMDA receptors, on antipsychotic-induced extrapyramidal side effects.2017
- Author(s)
  Saki Shimizu, Tomohiro Sekiguchi, Nanami Ikeda, Saya Okamura, Saki Itaya, Yukihiro Ohno
- Organizer
  第90回日本薬理学会総会
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K21501
[Presentation] ニコチン誘発振戦に対するセロトニン神経系の調節メカニズム2017
- Author(s)
  國澤直史、Higor A. Iha、清水佐紀、大野行弘
- Organizer
  第132回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16K21501
[Presentation] SK2チャネル遺伝子にミスセンス変異を持つ振戦ラット2017
- Author(s)
  庫本高志、横江繭子、国澤直史、大橋佳奈、三宅崇仁、樋口裕城、吉見一人、真下知二、田中美有、桑村　充、金子周二、清水佐紀、芹川忠夫、大野行弘
- Organizer
  第136回関西実験動物研究会
- Data Source
  KAKENHI-PROJECT-16K21501
[Presentation] Acute nicotine causes convulsive seizures by activating amygdala neurons, primarily through α7nACh receptors2016
- Author(s)
  Higor A. Iha、國澤直史、清水佐紀、熱田侑大、野原孝紀、吉川健斗、徳留健太郎、大野行弘
- Organizer
  第130回日本薬理学会近畿部会
- Place of Presentation
  京都
- Year and Date
  2016-11-19
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] シナプス小胞蛋白SV2A遺伝子変異ラットにおける扁桃核の興奮メカニズム解析2016
- Author(s)
  徳留健太郎、奥村貴裕、國澤直史、清水佐紀、金星匡人、玉田真弓、藤原汐里、三宅梨沙、芹川忠夫、真下知士、笹征史、大野行弘
- Organizer
  第130回日本薬理学会近畿部会
- Place of Presentation
  京都
- Year and Date
  2016-11-19
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Nicotine elicits limbic motor seizures primarily by activating amygdala neurons2016
- Author(s)
  Higor A. Iha, Naofumi Kunisawa, Saki Shimizu, Yudai Atsuta, Takanori Nohara, Keito Yoshikawa, Kentaro Tokudome and Yukihiro Ohno
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] シナプス小胞蛋白SV2Aの遺伝子変異による扁桃核の興奮メカニズム2016
- Author(s)
  三宅梨沙、玉田真弓、藤原汐里、徳留健太郎、芹川忠夫、清水佐紀、大野行弘
- Organizer
  第66回日本薬学会近畿支部総会
- Place of Presentation
  大阪
- Year and Date
  2016-10-15
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Analysis of causative brain regions for nicotine-induced seizures.2016
- Author(s)
  Naofumi Kunisawa, Higor A. Iha, Saki Shimizu, Yuto Mizuguchi, Takanori Nohara, Yudai Atsuta, Keito Yoshikawa, Kentaro Tokudome, Masato Kinboshi, Tadao Serikawa, Yukihiro Ohno
- Organizer
  第46回日本神経精神薬理学会年会
- Place of Presentation
  韓国（ソウル）
- Year and Date
  2016-07-02
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Nicotine evokes convulsive seizures by activating amygdala neurons partly through α7nACh receptors.2016
- Author(s)
  Higor A. Iha, Naofumi Kunisawa, Saki Shimizu, Yuto Mizuguchi, Takanori Nohara, Yudai Atsuta, Keito Yoshikawa, Kentaro Tokudome, Masato Kinboshi, Tadao Serikawa and Yukihiro Ohno
- Organizer
  30th CINP World congress of Neuropsychopharmacology
- Place of Presentation
  韓国（ソウル）
- Year and Date
  2016-07-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Pharmacological responses of nicotine-induced tremor to various anti-tremor agents.2016
- Author(s)
  Higor A. Iha, Naofumi Kunisawa, Saki Shimizu, Yudai Atsuta, Takanori Nohara, Kento Yoshikawa, Kentaro Tokudome, Yukihiro Ohno
- Organizer
  第46回日本神経精神薬理学会年会
- Place of Presentation
  韓国（ソウル）
- Year and Date
  2016-07-02
- Data Source
  KAKENHI-PROJECT-16K21501
[Presentation] Analysis of causative brain regions for nicotine-induced seizures.2016
- Author(s)
  Naofumi Kunisawa, Higor A. Iha, Saki Shimizu, Yuto Mizuguchi, Takanori Nohara, Yudai Atsuta, Keito Yoshikawa, Kentaro Tokudome, Masato Kinboshi, Tadao Serikawa, Yukihiro Ohno
- Organizer
  第46回日本神経精神薬理学会年会
- Place of Presentation
  韓国（ソウル）
- Year and Date
  2016-07-02
- Data Source
  KAKENHI-PROJECT-16K21501
[Presentation] A missense mutation of the synaptic vesicle glycoprotein 2A (SV2A) gene confers seizure susceptibility by disrupting amygdala GABA release.2016
- Author(s)
  Kentaro Tokudome, Takahiro Okumura, Naofumi Kunisawa, Saki Shimizu, Masato Kinboshi, Mayu Tamada, Shiori Fujiwara, Risa Miyake, Tadao Serikawa, Tomoji Mashimo, Masashi Sasa, Yukihiro Ohno
- Organizer
  第50回日本てんかん学会学術集会
- Place of Presentation
  静岡
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Analysis of causative brain regions for nicotine-induced seizures2016
- Author(s)
  Naofumi Kunisawa, Higor A. Iha, Saki Shimizu, Yuto Mizuguchi, Takanori Nohara, Yudai Atsuta, Keito Yoshikawa, Kentaro Tokudome, Masato Kinboshi, Tadao Serikawa, Yukihiro Ohno
- Organizer
  第46回日本神経精神薬理学会年会
- Place of Presentation
  韓国（ソウル）
- Year and Date
  2016-07-02
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Enhancement of the accumbal dopamine release by the gene mutation of synaptic vesicle protein 2A (Sv2aL174Q)2016
- Author(s)
  Kentaro Tokudome, Saki Shimizu, Naofumi Kunisawa, Azuki Hashimoto, Yuki Hiraoka, Kazuki Fukuda, Ayako Ikari, Yumiko Iguchi, Takafumi Sugahara, Tadao Serikawa, Yukihiro Ohno
- Organizer
  The 30th CINP World congress of Neuropsychopharmacology
- Place of Presentation
  韓国（ソウル）
- Year and Date
  2016-07-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Nicotine evokes convulsive seizures by activating amygdala neurons partly through α7nACh receptors.2016
- Author(s)
  Higor A. Iha, Naofumi Kunisawa, Saki Shimizu, Yuto Mizuguchi, Takanori Nohara, Yudai Atsuta, Keito Yoshikawa, Kentaro Tokudome, Masato Kinboshi, Tadao Serikawa, Yukihiro Ohno
- Organizer
  30th CINP World congress of Neuropsychopharmacology
- Place of Presentation
  Korea (Seoul)
- Year and Date
  2016-07-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21501
[Presentation] NMDA受容体グリシン結合部位活性化薬の線条体内ドパミン遊離に対する影響2016
- Author(s)
  関口知弘、池田菜々美、板谷紗希、岡村沙耶、秋葉健太、藤井　恵、山本真奈、清水佐紀、大野行弘
- Organizer
  第66回日本薬学会近畿支部総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-16K21501
[Presentation] ニコチン誘発振戦におけるセロトニン受容体の関与2016
- Author(s)
  野村有治、尾西美咲、松原菜美、國澤直史、Higor A. Iha、清水佐紀、河合悦子、大野行弘
- Organizer
  第66回日本薬学会近畿支部総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-16K21501
[Presentation] Pharmacological analysis of nicotine-induced tremor.2016
- Author(s)
  Naofumi Kunisawa, Higor A. Iha, Saki Shimizu, Yudai Atsuta, Takanori Nohara, Kento Yoshikawa, Kentaro Tokudome, Yukihiro Ohno
- Organizer
  30th CINP World congress of Neuropsychopharmacology
- Place of Presentation
  Korea (Seoul)
- Year and Date
  2016-07-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21501
[Presentation] ニコチン誘発振戦におけるセロトニン受容体の関与2016
- Author(s)
  野村有治、尾西美咲、松原菜美、國澤直史、Higor A. Iha、清水佐紀、河合悦子、大野行弘
- Organizer
  第66回日本薬学会近畿支部総会
- Place of Presentation
  大阪
- Year and Date
  2016-10-15
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Facilitation of kindling development by the gene mutation of synaptic vesicle protein 2A2016
- Author(s)
  Kentaro Tokudome, Takahiro Okumura, Tomoji Mashimo, Naofumi Kunisawa, Saki Shimizu, Ryo Terada1, Masato Kinboshi, Tadao Serikawa, Masashi Sasa, Yukihiro Ohno
- Organizer
  第46回日本神経精神薬理学会年会
- Place of Presentation
  韓国（ソウル）
- Year and Date
  2016-07-02
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Enhancement of the accumbal dopamine release by the gene mutation of synaptic vesicle protein 2A (Sv2aL174Q).2016
- Author(s)
  Kentaro Tokudome, Saki Shimizu, Naofumi Kunisawa, Azuki Hashimoto, Yuki Hiraoka, Kazuki Fukuda, Ayako Ikari, Yumiko Iguchi, Takafumi Sugahara, Tadao Serikawa, Yukihiro Ohno
- Organizer
  30th CINP World congress of Neuropsychopharmacology
- Place of Presentation
  韓国（ソウル）
- Year and Date
  2016-07-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Facilitation of kindling development by the gene mutation of synaptic vesicle protein 2A.2016
- Author(s)
  Kentaro Tokudome, Takahiro Okumura, Tomoji Mashimo, Naofumi Kunisawa, Saki Shimizu, Ryo Terada, Masato Kinboshi, Tadao Serikawa, Masashi Sasa, Yukihiro Ohno
- Organizer
  第46回日本神経精神薬理学会年会
- Place of Presentation
  韓国（ソウル）
- Year and Date
  2016-07-02
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Pharmacological analysis of nicotine-induced tremor2016
- Author(s)
  Naofumi Kunisawa, Higor A. Iha, Saki Shimizu, Yudai Atsuta, Takanori Nohara, Kento Yoshikawa, Kentaro Tokudome, Yukihiro Ohno
- Organizer
  30th CINP World congress of Neuropsychopharmacology
- Place of Presentation
  韓国（ソウル）
- Year and Date
  2016-07-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Evaluation of the extrapyramidal side effects (EPS) liability of NMDA receptor glycine-binding site agonists.2016
- Author(s)
  Yukihiro Ohno, Yuka Sato, Syodai Fujii, Ryo Wakamatsu, Haruna Takasaki, Megumi Yamanaka, Akiyoshi Inada, Syunsaku Sogabe, Ryoto Yanagisako, Saki Shimizu
- Organizer
  30th CINP World congress of Neuropsychopharmacology
- Place of Presentation
  Korea (Seoul)
- Year and Date
  2016-07-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21501
[Presentation] Nicotine evokes convulsive seizures by activating amygdala neurons partly through α7nACh receptors2016
- Author(s)
  Higor A. Iha, Naofumi Kunisawa, Saki Shimizu, Yuto Mizuguchi, Takanori Nohara, Yudai Atsuta, Keito Yoshikawa, Kentaro Tokudome, Masato Kinboshi, Tadao Serikawa and Yukihiro Ohno
- Organizer
  The 30th CINP World congress of Neuropsychopharmacology
- Place of Presentation
  韓国（ソウル）
- Year and Date
  2016-07-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] ニコチンによる運動興奮症状の発現メカニズム解析2016
- Author(s)
  國澤直史、Higor A. Iha、清水佐紀、尾西美咲、野村有治、松原菜美、徳留健太郎、河合悦子、大野行弘
- Organizer
  第66回日本薬学会近畿支部総会
- Place of Presentation
  大阪
- Year and Date
  2016-10-15
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Acute nicotine causes convulsive seizures by activating amygdala neurons, primarily through α7nACh receptors.2016
- Author(s)
  Higor A. Iha、國澤直史、清水佐紀、熱田侑大、野原孝紀、吉川健斗、徳留健太郎、大野行弘
- Organizer
  第130回日本薬理学会近畿部会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-16K21501
[Presentation] Pharmacological responses of nicotine-induced tremor to various anti-tremor agents.2016
- Author(s)
  Higor A. Iha, Naofumi Kunisawa, Saki Shimizu, Yudai Atsuta, Takanori Nohara, Kento Yoshikawa, Kentaro Tokudome, Yukihiro Ohno
- Organizer
  第46回日本神経精神薬理学会年会
- Place of Presentation
  韓国（ソウル）
- Year and Date
  2016-07-02
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] ニコチンによる運動興奮症状の発現メカニズム解析2016
- Author(s)
  國澤直史、Higor A. Iha、清水佐紀、尾西美咲、野村有治、松原菜美、徳留健太郎、河合悦子、大野行弘
- Organizer
  第66回日本薬学会近畿支部総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-16K21501
[Presentation] Amygdala is the primary causative site for nicotine-induced convulsive seizures2015
- Author(s)
  Higor A. Iha, Naofumi Kunisawa, Saki Shimizu, Yuto Mizuguchi, Miyuki Ohtaka, Hisao Chikamochi, Yuichi Takakubo, Kentaro Tokudome, Yukihiro Ohno
- Organizer
  第38回日本神経科学会
- Place of Presentation
  神戸
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] ニコチン誘発けいれんの原因部位およびメカニズムの解析2015
- Author(s)
  國澤直史、清水佐紀、Higor A. Iha、大高美幸、近持壽郎、高久保佑一、熱田侑大、野原孝紀、吉川健斗、徳留健太郎、河合悦子、大野行弘
- Organizer
  第42回日本毒性学会学術年会
- Place of Presentation
  金沢
- Year and Date
  2015-06-29
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Mutation of the gene encoding synaptic vesicle protein 2A (SV2A) markedly facilitates the kindling epileptogenesis in rats2015
- Author(s)
  Kentaro Tokudome, Takahiro Okumura, Tomoji Mashimo, Naofumi Kunisawa, Saki Shimizu, Ryo Terada, Tadao Serikawa, Masashi Sasa, Yukihiro Ohno
- Organizer
  The 4th Congress of Asian College of Neuropsychopharmacology
- Place of Presentation
  台湾（台北）
- Year and Date
  2015-11-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Mechanisms underlying the kindling facilitation by the gene mutation of synaptic vesicle protein 2A (SV2A)2015
- Author(s)
  Kentaro Tokudome, Takahiro Okumura, Naofumi Kunisawa, Kinboshi Masato, Saki Shimizu, Tomoji Mashimo, Tadao Serikawa, Masashi Sasa, Yukihiro Ohno
- Organizer
  第49回日本てんかん学会
- Place of Presentation
  長崎
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Mutation of the gene encoding synaptic vesicle protein 2A (SV2A) markedly facilitates the kindling epileptogenesis in rats2015
- Author(s)
  Naofumi Kunisawa, Kentaro Tokudome, Takahiro Okumura, Saki Shimizu, Masato Kinboshi, Tomoji Mashimo, Tadao Serikawa, Masashi Sasa, Yukihiro Ohno
- Organizer
  第49回日本てんかん学会
- Place of Presentation
  長崎
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Nicotine provokes seizures by activating amygdala neurons partly through α7-nACh receptors2015
- Author(s)
  Higor A. Iha, Naofumi Kunisawa, Saki Shimizu, Yuto Mizuguchi, Miyuki Ohtaka, Hisao Chikamochi, Yuichi Takakubo, Kentaro Tokudome, Masato Kinboshi, Yukihiro Ohno
- Organizer
  第49回日本てんかん学会
- Place of Presentation
  長崎
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Pharmacological analysis for the mechanism of nicotine-induced seizures in rats
- Author(s)
  Naofumi Kunisawa, Saki Shimizu, Yuto Mizuguchi, Takahiro Okumura, Miyuki Ohtaka, Hisao Chikamochi, Yuichi Takakubo, Kentaro Tokudome, Tadao Serikawa, Yukihiro Ohno
- Organizer
  第48回日本てんかん学会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-10-02 – 2014-10-03
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Amygdala is the primary causative site for nicotine-induced convulsive seizures
- Author(s)
  Higor A. Iha, Naofumi Kunisawa, Saki Shimizu, Yuto Mizuguchi, Miyuki Ohtaka, Hisao Chikamochi, Yuichi Takakubo, Kentaro Tokudome, Yukihiro Ohno
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸
- Year and Date
  2015-07-28 – 2015-07-31
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Enhanced kindling development in synaptic vesicle protein 2A-mutant (Sv2aL174Q) rats
- Author(s)
  Kentaro Tokudome, Takahiro Okumura, Tomoji Mashimo, Naofumi Kunisawa, Saki Shimizu, Ryo Terada, Tadao Serikawa, Masashi Sasa, Yukihiro Ohno
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Pharmacological mechanisms of nicotine-induced convulsive seizures in mice
- Author(s)
  Higor A. Iha, Naofumi Kunisawa, Saki Shimizu, Yuto Mizuguchi, Miyuki Ohtaka, Hisao Chikamochi, Yuichi Takakubo, Kentaro Tokudome, Tadao Serikawa, Yukihiro Ohno
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Evaluation of seizure susceptibility in the synaptic vesicle protein 2A (SV2A)-mutant rats
- Author(s)
  Kentaro Tokudome, Takahiro Okumura, Tomoji Mashimo, Tadao Serikawa, Naofumi Kunisawa, Saki Shimizu, Masashi Sasa, Yukihiro Ohno
- Organizer
  第48回日本てんかん学会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-10-02 – 2014-10-03
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] ニコチンによるけいれん発現のメカニズム解析
- Author(s)
  大野行弘、國澤直史、水口裕登、奥村貴裕、徳留健太郎、落合　緑、溝辺雄輔、田村深雪、大高美幸、近持壽郎、高久保佑一、河合悦子、清水佐紀
- Organizer
  第41回日本毒性学会学術年会
- Place of Presentation
  神戸
- Year and Date
  2014-07-02 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Analysis of brain regions responsible for nicotine-induced convulsions
- Author(s)
  Naofumi Kunisawa, Saki Shimizu, Yuto Mizuguchi, Takahiro Okumura, Kentaro Tokudome, Miyuki Ohtaka, Hisao Chikamochi, Yuichi Takakubo, Tadao Serikawa, Yukihiro Ohno
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] ニコチンによるけいれん発現の薬理学的解析
- Author(s)
  國澤直史、清水佐紀、水口裕登、奥村貴裕、大高美幸、近持壽郎、高久保佑一、徳留健太郎、芹川忠夫、大野行弘
- Organizer
  第44回日本神経精神薬理学会・第24回日本臨床精神神経薬理学会合同学会
- Place of Presentation
  名古屋
- Year and Date
  2014-11-20 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-26460111

1. Yukihiro Ohno (00432534)

# of Collaborated Projects: 2 results

# of Collaborated Products: 60 results
2. KAWAI YOSHIKO (50268299)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
3. 國澤直史 (10858096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
4. 真下知士

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Shimizu Saki 清水 佐紀

SHIMIZU SAKI 清水 佐紀

Research Projects

Research Products

Co-Researchers

Analysis of the mechanisms underlying development of neuropsychiatric diseases with focus on astrocytic potassium buffering function

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Analysis of the modulation mechanism in induction of epileptic seizure via hyperpolarization activated cyclic nucleotide-gated (HCN) channel 1Principal Investigator

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Pathophysiological analysis of essential tremor and identification of the novel therapeutic targets.Principal Investigator

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Pathophysiological analysis of epilepsy with focusing on the synaptic release mechanism

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[Book] In Vivo Neuropharmacology and Neurophysiology2016

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[Journal Article] Mechanisms Underlying Dopaminergic Regulation of Nicotine-Induced Kinetic Tremor2022

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[Journal Article] Emerging Roles of Astrocyte Kir4.1 Channels in the Pathogenesis and Treatment of Brain Diseases.2021

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[Journal Article] Involvement of NMDA receptors in tremor expression in <i>Aspa</i>/<i>Hcn1</i> double-knockout rats2020

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[Journal Article] Mechanism Underlying Organophosphate Paraoxon-Induced Kinetic Tremor.2019

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[Journal Article] Down-Regulation of Astrocytic Kir4.1 Channels during the Audiogenic Epileptogenesis in Leucine-Rich Glioma-Inactivated 1 (Lgi1) Mutant Rats.2019

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[Journal Article] Pharmacological characterization of nicotine-induced tremor: Responses to anti-tremor and anti-epileptic agents.2018

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[Journal Article] Inwardly rectifying potassium channel Kir4.1 as a novel modulator of BDNF expression in astrocytes.2018

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[Journal Article] Glycine-Binding Site Stimulants of NMDA Receptors Alleviate Extrapyramidal Motor Disorders by Activating the Nigrostriatal Dopaminergic Pathway2017

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[Journal Article] Serotonergic modulation of nicotine-induced kinetic tremor in mice2017

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Shimizu Saki 清水佐紀

SHIMIZU SAKI 清水佐紀

[Presentation] Kir4.1チャネル阻害薬quinacrineの神経炎症を伴う認知機能障害に対する改善作用2024