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Ohta Shinya  太田 信哉

… Alternative Names

太田 信哉  オオタ シンヤ

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Researcher Number 00631194
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-2424-1741
Affiliation (Current) 2025: 北海道大学, 遺伝子病制御研究所, 准教授
Affiliation (based on the past Project Information) *help 2025: 北海道大学, 遺伝子病制御研究所, 准教授
2022 – 2023: 北海道大学, 遺伝子病制御研究所, 准教授
2020: 北海道大学, 遺伝子病制御研究所, 准教授
2016 – 2019: 高知大学, 教育研究部医療学系基礎医学部門, 講師
2015: 高知大学, 教育研究部医療学系基礎医学部門, 特任助教
2012 – 2014: 高知大学, 教育研究部医療学系, 特任助教
2013: 高知大学, 医歯学系, その他
Review Section/Research Field
Principal Investigator
Molecular biology / Basic Section 59040:Nutrition science and health science-related / Basic Section 43010:Molecular biology-related / Cell biology
Except Principal Investigator
Biological Science
Keywords
Principal Investigator
染色体 / 分裂期 / クロマチン / セントロメア / プロテオミクス / ヘテロクロマチン / ゲノム / キネトコア / 染色体分配
Except Principal Investigator
ヒト … More / コンデンシン / ゲノミクス / 転写制御 / 細胞老化 / 分裂酵母 / クロマチンドメイン / 3Dゲノム構造 Less
  • Research Projects

    (6 results)
  • Research Products

    (28 results)
  • Co-Researchers

    (4 People)
  •  3Dゲノム構造を介した細胞老化に伴う遺伝子発現変容機構Principal Investigator

    • Principal Investigator
      太田 信哉
    • Project Period (FY)
      2025 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Hokkaido University
  •  分裂酵母とヒトの3Dゲノム構造とその形成機構の解明

    • Principal Investigator
      野間 健一
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Fund for the Promotion of Joint International Research (Home-Returning Researcher Development Research)
    • Review Section
      Biological Science
    • Research Institution
      Hokkaido University
  •  Novel mechanism of pericentromere-specific heterochromatin formationPrincipal Investigator

    • Principal Investigator
      Ohta Shinya
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43010:Molecular biology-related
    • Research Institution
      Hokkaido University
      Kochi University
  •  Functional analysis of novel centromere/kinetochore proteins in mitosisPrincipal Investigator

    • Principal Investigator
      Ohta Shinya
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Molecular biology
    • Research Institution
      Kochi University
  •  Identification and functional analysis of novel vertebrate chromosomal proteins with using Multi-Classifier Combinational ProteomicsPrincipal Investigator

    • Principal Investigator
      Ohta Shinya
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Molecular biology
    • Research Institution
      Kochi University
  •  多次元プロテオミクスを利用した新規染色体タンパク質の探索Principal Investigator

    • Principal Investigator
      太田 信哉
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Cell biology
    • Research Institution
      Kochi University

All 2023 2021 2020 2019 2018 2017 2016 2015 2013 Other

All Journal Article Presentation

  • [Journal Article] Chemo-senolytic therapeutic potential against angiosarcoma2023

    • Author(s)
      Wang Xuebing、Chung Claire Yik-Lok、Yoshioka Ai、Hashimoto Shinya、Jimbo Haruki、Tanizawa Hideki、Ohta Shinya、Fukumoto Takeshi、Noma Ken-ichi
    • Journal Title

      Journal of Investigative Dermatology

      Volume: -

    • DOI

      10.1101/2023.10.19.563192

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K23376
  • [Journal Article] Proteomics analysis understanding the regulation system of mitotic chromosome structure2018

    • Author(s)
      太田 信哉
    • Journal Title

      Proteome Letters

      Volume: 2(2) Pages: 294-299

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K18494
  • [Journal Article] Quantitative Proteomics of the Mitotic Chromosome Scaffold Reveals the Association of BAZ1B with Chromosomal Axes2018

    • Author(s)
      Ohta Shinya、Taniguchi Takako、Sato Nobuko、Hamada Mayako、Taniguchi Hisaaki、Rappsilber Juri
    • Journal Title

      Molecular & Cellular Proteomics

      Volume: 18 Issue: 2 Pages: 169-181

    • DOI

      10.1074/mcp.ra118.000923

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06061
  • [Journal Article] HP1α targets the chromosomal passenger complex for activation at heterochromatin before mitotic entry.2018

    • Author(s)
      Ruppert JG, Samejima K, Platani M, Molina O, Kimura H, Jeyaprakash AA, Ohta S, Earnshaw WC.
    • Journal Title

      EMBO J

      Volume: 37 Issue: 6

    • DOI

      10.15252/embj.201797677

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26291071, KAKENHI-PLANNED-25116005, KAKENHI-PROJECT-16K18494, KAKENHI-INTERNATIONAL-15K21730
  • [Journal Article] Nano Random Forests to mine protein complexes and their relationships in quantitative proteomics data.2017

    • Author(s)
      Montano-Gutierrez LF, Ohta S, Kustatscher G, Earnshaw WC, Rappsilber J.
    • Journal Title

      Mol Biol Cell.

      Volume: 28(5) Issue: 5 Pages: 673-680

    • DOI

      10.1091/mbc.e16-06-0370

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K18494
  • [Journal Article] Identification of Mitosis-Specific Phosphorylation in Mitotic Chromosome-Associated Proteins.2016

    • Author(s)
      Ohta S, Kimura M, Takagi S, Toramoto I, Ishihama Y.
    • Journal Title

      J Proteome Res.

      Volume: 15(9) Issue: 9 Pages: 3331-3341

    • DOI

      10.1021/acs.jproteome.6b00512

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K18494
  • [Journal Article] Auxin/AID versus conventional knockouts: Distinguishing the roles of CENP-T/W in mitotic kinetochore assembly and stability2016

    • Author(s)
      Laura Wood, Daniel G. Booth, Giulia Vargiu, Shinya Ohta, Flavia deLima Alves, Kumiko Samejima, Tatsuo Fukagawa, Juri Rappsilber, and William C Earnshaw
    • Journal Title

      Open Biology

      Volume: 6(1) Issue: 1 Pages: 150230-150230

    • DOI

      10.1098/rsob.150230

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25870487, KAKENHI-PLANNED-15H05972, KAKENHI-PROJECT-25221106
  • [Journal Article] Proteomics analysis with a nano Random Forest approach reveals novel functional interactions regulated by SMC complexes on mitotic chromosomes.2016

    • Author(s)
      Ohta S, Montano-Gutierrez LF, Alves FL, Ogawa H, Toramoto I, Sato N, Morrison CG, Takeda S, Hudson DF, Rappsilber J, Earnshaw WC
    • Journal Title

      Mol Cell Proteomics

      Volume: 15 Issue: 8 Pages: 2802-2818

    • DOI

      10.1074/mcp.m116.057885

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06306, KAKENHI-PROJECT-16K18494
  • [Journal Article] Polyglutamylated tubulin binding protein C1orf96/CSAP is involved in microtubule stabilization in mitotic spindles2015

    • Author(s)
      Shinya Ohta, Mayako Hamada, Nobuko Sato, Iyo Toramoto
    • Journal Title

      PLOS ONE

      Volume: 10(11) Issue: 11 Pages: e0142798-e0142798

    • DOI

      10.1371/journal.pone.0142798

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25870487
  • [Journal Article] CENP-32 is required to maintain centrosomal dominance in bipolar spindle assembly2015

    • Author(s)
      Shinya Ohta, Laura Wood, Iyo Toramoto, Ken-Ichi Yagyu, Tatsuo Fukagawa, and William C. Earnshaw
    • Journal Title

      Molecular Biology of the Cell.

      Volume: 26(7) Issue: 7 Pages: 1225-1237

    • DOI

      10.1091/mbc.e14-09-1366

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25870487, KAKENHI-PLANNED-15H05972, KAKENHI-PUBLICLY-26114715, KAKENHI-PROJECT-25221106
  • [Journal Article] 曖昧なプロテオミクス(Fuzzy Proteomics)による分裂期染色体構造の決定2013

    • Author(s)
      太田 信哉
    • Journal Title

      The lung

      Volume: 21(3) Pages: 294-299

    • Data Source
      KAKENHI-PROJECT-25870487
  • [Presentation] 細胞老化に伴うゲノム構造の再編成メカニズムをプロテオミクスで明らかにする2023

    • Author(s)
      太田信哉
    • Organizer
      日本プロテオーム学会 2023 年大会
    • Data Source
      KAKENHI-PROJECT-20K23376
  • [Presentation] 細胞老化に伴うトランスクリプトームと核内プロテオームの変化2023

    • Author(s)
      太田信哉
    • Organizer
      第9回北大・部局横断シンポジウム
    • Data Source
      KAKENHI-PROJECT-20K23376
  • [Presentation] ZNF518によるCENP-B依存的なペロセントロメア特異的ヘテロクロマチン化メカニズム2021

    • Author(s)
      太田 信哉
    • Organizer
      第38回染色体ワークショップ・第19回核ダイナミクス研究会
    • Data Source
      KAKENHI-PROJECT-18K06061
  • [Presentation] AIRIを介した新規ペリセントロメアヘテロクロマチン化機構2020

    • Author(s)
      太田 信哉、野間 健一
    • Organizer
      第6回 北海道大学・部局横断シンポジウム
    • Data Source
      KAKENHI-PROJECT-18K06061
  • [Presentation] ZNF518 proteins are involved in CENP-B dependent pericentromeric heterochromatization2020

    • Author(s)
      太田 信哉
    • Organizer
      第43回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18K06061
  • [Presentation] Proteomics analysis of mitotic chromosomes with using nano Random Forest2019

    • Author(s)
      Shinya Ohta
    • Organizer
      The Korean Human Proteome Organization Annual International Proteomics Conference 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06061
  • [Presentation] 分裂期染色体のプロテオミクス解析2017

    • Author(s)
      太田 信哉
    • Organizer
      第15回日本プロテオーム学会2017年会
    • Data Source
      KAKENHI-PROJECT-16K18494
  • [Presentation] Quantitative proteomics revealed that BAZ1 proteins regulate the precious timing of chromosome condensation in early mitosis2017

    • Author(s)
      太田 信哉
    • Organizer
      第15回日本プロテオーム学会2017年会
    • Data Source
      KAKENHI-PROJECT-16K18494
  • [Presentation] 定量プロテオミクスを用いた新規分裂期染色体軸索タンパク質の発見2016

    • Author(s)
      太田 信哉
    • Organizer
      第57回 日本生化学会中国・四国支部例会
    • Place of Presentation
      高知大学岡豊キャンパス(高知県・南国市)
    • Year and Date
      2016-05-27
    • Data Source
      KAKENHI-PROJECT-16K18494
  • [Presentation] 定量プロテオミクスを用いた新規分裂期染色体軸索タンパク質の同定2016

    • Author(s)
      太田 信哉
    • Organizer
      日本遺伝学会 第88回大会
    • Place of Presentation
      日本大学三島キャンパス(静岡県・三島市)
    • Year and Date
      2016-09-07
    • Data Source
      KAKENHI-PROJECT-16K18494
  • [Presentation] Proteomics study of vertebrate mitotic chromosomes.2013

    • Author(s)
      Itaru Samejima, Flavia de Lima Alves, Shinya Ohta, Juri Rappsilber, Tatsuo Fukagawa and William C Earnshaw
    • Organizer
      Gordon Research Conference – chromosome dynamics
    • Place of Presentation
      ルネッサンストスカーニャホテル(ルッカ イタリア)
    • Data Source
      KAKENHI-PROJECT-25870487
  • [Presentation] Defining the structure of mitotic chromosomes using multi-classifier combinatorial proteomics together with DT40 genetics2013

    • Author(s)
      Shinya Ohta, Laura Wood, Jimi-Carlo Bukowski-Wills, Itaru Samejima Luis Fernando Montano, Juri Rappsilber and William C. Earnshaw
    • Organizer
      12th Human Proteome Organisation World Congress
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Data Source
      KAKENHI-PROJECT-25870487
  • [Presentation] 多次元プロテオミクスを用いた分裂期染色体構造の解析2013

    • Author(s)
      太田 信哉
    • Organizer
      第2回JHUPOサテライトシンポジウム
    • Place of Presentation
      愛媛大学(松山)
    • Data Source
      KAKENHI-PROJECT-25870487
  • [Presentation] 多次元プロテオミクスによる分裂期染色体の制御構造解析2013

    • Author(s)
      太田 信哉, Luis Fernando Montaño, Laura Wood, Itaru, Samejima, Flavia de Lima Alves, Juri Rapsilber, William C Earnshaw
    • Organizer
      第64回日本染色体学会年会
    • Place of Presentation
      富山大学(富山)
    • Data Source
      KAKENHI-PROJECT-25870487
  • [Presentation] プロテオミクスと遺伝学の融合による分裂期染色体の制御構造解析2013

    • Author(s)
      太田 信哉, Laura Wood, Juri Rappsilber, William C. Earnshaw
    • Organizer
      第85回日本遺伝学会年会
    • Place of Presentation
      慶応大学(横浜)
    • Data Source
      KAKENHI-PROJECT-25870487
  • [Presentation] プロテオミクスによる分裂期クロマチン制御構造の解析

    • Author(s)
      太田 信哉
    • Organizer
      第32回染色体ワークショップ、第13回核ダイナミクス研究会
    • Place of Presentation
      広島 (安芸グランドホテル)
    • Year and Date
      2014-12-12 – 2014-12-14
    • Data Source
      KAKENHI-PROJECT-25870487
  • [Presentation] 分裂期染色体上におけるタンパク質リン酸化の網羅的解析

    • Author(s)
      太田 信哉, 高木 俊輔, 木村 迪子, 石濱 泰
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      横浜 (パシフィコ横浜)
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-25870487
  • 1.  野間 健一 (30900039)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 2.  谷澤 英樹 (70402550)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  木村 宏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 4.  武田 俊一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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