Ohta Shinya 太田信哉

… Alternative Names

太田信哉オオタシンヤ

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Researcher Number	00631194
Other IDs	https://orcid.org/0000-0003-2424-1741
Affiliation (Current)	2025: 北海道大学, 遺伝子病制御研究所, 准教授
Affiliation (based on the past Project Information) *help	2025: 北海道大学, 遺伝子病制御研究所, 准教授 2022 – 2023: 北海道大学, 遺伝子病制御研究所, 准教授 2020: 北海道大学, 遺伝子病制御研究所, 准教授 2016 – 2019: 高知大学, 教育研究部医療学系基礎医学部門, 講師 2015: 高知大学, 教育研究部医療学系基礎医学部門, 特任助教 2012 – 2014: 高知大学, 教育研究部医療学系, 特任助教 2013: 高知大学, 医歯学系, その他
Review Section/Research Field	Principal Investigator Molecular biology / Basic Section 59040:Nutrition science and health science-related / Basic Section 43010:Molecular biology-related / Cell biology Except Principal Investigator Basic Section 43050:Genome biology-related / Biological Science
Keywords	Principal Investigator 染色体 / クロマチン / 分裂期 / セントロメア / プロテオミクス / 遺伝子発現 / 細胞老化 / ヘテロクロマチン / ゲノム / キネトコア / 染色体分配 … More Except Principal Investigator … More 分裂酵母 / Rループ / 転写 / 分裂期 / ゲノム構造 / ヒト / コンデンシン / ゲノミクス / 転写制御 / 細胞老化 / クロマチンドメイン / 3Dゲノム構造 Less

染色体分離と転写を結び付ける分子機構の解明
- Principal Investigator
  
  野間健一
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43050:Genome biology-related
- Research Institution
  Hokkaido University
3Dゲノム構造を介した細胞老化に伴う遺伝子発現変容機構Principal Investigator
- Principal Investigator
  
  太田信哉
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Hokkaido University
分裂酵母とヒトの３Ｄゲノム構造とその形成機構の解明
- Principal Investigator
  
  野間健一
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Home-Returning Researcher Development Research)
- Review Section
  
  Biological Science
- Research Institution
  Hokkaido University
Novel mechanism of pericentromere-specific heterochromatin formationPrincipal Investigator
- Principal Investigator
  
  Ohta Shinya
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Hokkaido University
  Kochi University
Functional analysis of novel centromere/kinetochore proteins in mitosisPrincipal Investigator
- Principal Investigator
  
  Ohta Shinya
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Molecular biology
- Research Institution
  Kochi University
Identification and functional analysis of novel vertebrate chromosomal proteins with using Multi-Classifier Combinational ProteomicsPrincipal Investigator
- Principal Investigator
  
  Ohta Shinya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Molecular biology
- Research Institution
  Kochi University
多次元プロテオミクスを利用した新規染色体タンパク質の探索Principal Investigator
- Principal Investigator
  
  太田信哉
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Cell biology
- Research Institution
  Kochi University

All 2023 2021 2020 2019 2018 2017 2016 2015 2013 Other

All Journal Article Presentation

[Journal Article] Chemo-senolytic therapeutic potential against angiosarcoma2023
- Author(s)
  Wang Xuebing、Chung Claire Yik-Lok、Yoshioka Ai、Hashimoto Shinya、Jimbo Haruki、Tanizawa Hideki、Ohta Shinya、Fukumoto Takeshi、Noma Ken-ichi
- Journal Title
  
  Journal of Investigative Dermatology
  
  Volume: -
- DOI
  10.1101/2023.10.19.563192
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K23376
[Journal Article] Proteomics analysis understanding the regulation system of mitotic chromosome structure2018
- Author(s)
  太田信哉
- Journal Title
  
  Proteome Letters
  
  Volume: 2(2) Pages: 294-299
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K18494
[Journal Article] Quantitative Proteomics of the Mitotic Chromosome Scaffold Reveals the Association of BAZ1B with Chromosomal Axes2018
- Author(s)
  Ohta Shinya、Taniguchi Takako、Sato Nobuko、Hamada Mayako、Taniguchi Hisaaki、Rappsilber Juri
- Journal Title
  
  Molecular & Cellular Proteomics
  
  Volume: 18 Issue: 2 Pages: 169-181
- DOI
  10.1074/mcp.ra118.000923
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06061
[Journal Article] HP1α targets the chromosomal passenger complex for activation at heterochromatin before mitotic entry.2018
- Author(s)
  Ruppert JG, Samejima K, Platani M, Molina O, Kimura H, Jeyaprakash AA, Ohta S, Earnshaw WC.
- Journal Title
  
  EMBO J
  
  Volume: 37 Issue: 6
- DOI
  10.15252/embj.201797677
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291071, KAKENHI-PLANNED-25116005, KAKENHI-PROJECT-16K18494, KAKENHI-INTERNATIONAL-15K21730
[Journal Article] Nano Random Forests to mine protein complexes and their relationships in quantitative proteomics data.2017
- Author(s)
  Montano-Gutierrez LF, Ohta S, Kustatscher G, Earnshaw WC, Rappsilber J.
- Journal Title
  
  Mol Biol Cell.
  
  Volume: 28(5) Issue: 5 Pages: 673-680
- DOI
  10.1091/mbc.e16-06-0370
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18494
[Journal Article] Identification of Mitosis-Specific Phosphorylation in Mitotic Chromosome-Associated Proteins.2016
- Author(s)
  Ohta S, Kimura M, Takagi S, Toramoto I, Ishihama Y.
- Journal Title
  
  J Proteome Res.
  
  Volume: 15(9) Issue: 9 Pages: 3331-3341
- DOI
  10.1021/acs.jproteome.6b00512
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K18494
[Journal Article] Auxin/AID versus conventional knockouts: Distinguishing the roles of CENP-T/W in mitotic kinetochore assembly and stability2016
- Author(s)
  Laura Wood, Daniel G. Booth, Giulia Vargiu, Shinya Ohta, Flavia deLima Alves, Kumiko Samejima, Tatsuo Fukagawa, Juri Rappsilber, and William C Earnshaw
- Journal Title
  
  Open Biology
  
  Volume: 6(1) Issue: 1 Pages: 150230-150230
- DOI
  10.1098/rsob.150230
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25870487, KAKENHI-PLANNED-15H05972, KAKENHI-PROJECT-25221106
[Journal Article] Proteomics analysis with a nano Random Forest approach reveals novel functional interactions regulated by SMC complexes on mitotic chromosomes.2016
- Author(s)
  Ohta S, Montano-Gutierrez LF, Alves FL, Ogawa H, Toramoto I, Sato N, Morrison CG, Takeda S, Hudson DF, Rappsilber J, Earnshaw WC
- Journal Title
  
  Mol Cell Proteomics
  
  Volume: 15 Issue: 8 Pages: 2802-2818
- DOI
  10.1074/mcp.m116.057885
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06306, KAKENHI-PROJECT-16K18494
[Journal Article] Polyglutamylated tubulin binding protein C1orf96/CSAP is involved in microtubule stabilization in mitotic spindles2015
- Author(s)
  Shinya Ohta, Mayako Hamada, Nobuko Sato, Iyo Toramoto
- Journal Title
  
  PLOS ONE
  
  Volume: 10(11) Issue: 11 Pages: e0142798-e0142798
- DOI
  10.1371/journal.pone.0142798
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25870487
[Journal Article] CENP-32 is required to maintain centrosomal dominance in bipolar spindle assembly2015
- Author(s)
  Shinya Ohta, Laura Wood, Iyo Toramoto, Ken-Ichi Yagyu, Tatsuo Fukagawa, and William C. Earnshaw
- Journal Title
  
  Molecular Biology of the Cell.
  
  Volume: 26(7) Issue: 7 Pages: 1225-1237
- DOI
  10.1091/mbc.e14-09-1366
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25870487, KAKENHI-PLANNED-15H05972, KAKENHI-PUBLICLY-26114715, KAKENHI-PROJECT-25221106
[Journal Article] 曖昧なプロテオミクス(Fuzzy Proteomics)による分裂期染色体構造の決定2013
- Author(s)
  太田　信哉
- Journal Title
  
  The lung
  
  Volume: 21(3) Pages: 294-299
- Data Source
  KAKENHI-PROJECT-25870487
[Presentation] 細胞老化に伴うゲノム構造の再編成メカニズムをプロテオミクスで明らかにする2023
- Author(s)
  太田信哉
- Organizer
  日本プロテオーム学会 2023 年大会
- Data Source
  KAKENHI-PROJECT-20K23376
[Presentation] 細胞老化に伴うトランスクリプトームと核内プロテオームの変化2023
- Author(s)
  太田信哉
- Organizer
  第9回北大・部局横断シンポジウム
- Data Source
  KAKENHI-PROJECT-20K23376
[Presentation] ZNF518によるCENP-B依存的なペロセントロメア特異的ヘテロクロマチン化メカニズム2021
- Author(s)
  太田　信哉
- Organizer
  第38回染色体ワークショップ・第19回核ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-18K06061
[Presentation] AIRIを介した新規ペリセントロメアヘテロクロマチン化機構2020
- Author(s)
  太田　信哉、野間　健一
- Organizer
  第6回北海道大学・部局横断シンポジウム
- Data Source
  KAKENHI-PROJECT-18K06061
[Presentation] ZNF518 proteins are involved in CENP-B dependent pericentromeric heterochromatization2020
- Author(s)
  太田　信哉
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06061
[Presentation] Proteomics analysis of mitotic chromosomes with using nano Random Forest2019
- Author(s)
  Shinya Ohta
- Organizer
  The Korean Human Proteome Organization Annual International Proteomics Conference 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06061
[Presentation] 分裂期染色体のプロテオミクス解析2017
- Author(s)
  太田信哉
- Organizer
  第15回日本プロテオーム学会2017年会
- Data Source
  KAKENHI-PROJECT-16K18494
[Presentation] Quantitative proteomics revealed that BAZ1 proteins regulate the precious timing of chromosome condensation in early mitosis2017
- Author(s)
  太田信哉
- Organizer
  第15回日本プロテオーム学会2017年会
- Data Source
  KAKENHI-PROJECT-16K18494
[Presentation] 定量プロテオミクスを用いた新規分裂期染色体軸索タンパク質の発見2016
- Author(s)
  太田信哉
- Organizer
  第57回日本生化学会中国・四国支部例会
- Place of Presentation
  高知大学岡豊キャンパス（高知県・南国市）
- Year and Date
  2016-05-27
- Data Source
  KAKENHI-PROJECT-16K18494
[Presentation] 定量プロテオミクスを用いた新規分裂期染色体軸索タンパク質の同定2016
- Author(s)
  太田信哉
- Organizer
  日本遺伝学会第88回大会
- Place of Presentation
  日本大学三島キャンパス（静岡県・三島市）
- Year and Date
  2016-09-07
- Data Source
  KAKENHI-PROJECT-16K18494
[Presentation] Proteomics study of vertebrate mitotic chromosomes.2013
- Author(s)
  Itaru Samejima, Flavia de Lima Alves, Shinya Ohta, Juri Rappsilber, Tatsuo Fukagawa and William C Earnshaw
- Organizer
  Gordon Research Conference – chromosome dynamics
- Place of Presentation
  ルネッサンストスカーニャホテル（ルッカ　イタリア）
- Data Source
  KAKENHI-PROJECT-25870487
[Presentation] Defining the structure of mitotic chromosomes using multi-classifier combinatorial proteomics together with DT40 genetics2013
- Author(s)
  Shinya Ohta, Laura Wood, Jimi-Carlo Bukowski-Wills, Itaru Samejima Luis Fernando Montano, Juri Rappsilber and William C. Earnshaw
- Organizer
  12th Human Proteome Organisation World Congress
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-25870487
[Presentation] 多次元プロテオミクスを用いた分裂期染色体構造の解析2013
- Author(s)
  太田信哉
- Organizer
  第2回JHUPOサテライトシンポジウム
- Place of Presentation
  愛媛大学（松山）
- Data Source
  KAKENHI-PROJECT-25870487
[Presentation] 多次元プロテオミクスによる分裂期染色体の制御構造解析2013
- Author(s)
  太田信哉, Luis Fernando Montaño, Laura Wood, Itaru, Samejima, Flavia de Lima Alves, Juri Rapsilber, William C Earnshaw
- Organizer
  第64回日本染色体学会年会
- Place of Presentation
  富山大学（富山）
- Data Source
  KAKENHI-PROJECT-25870487
[Presentation] プロテオミクスと遺伝学の融合による分裂期染色体の制御構造解析2013
- Author(s)
  太田信哉, Laura Wood, Juri Rappsilber, William C. Earnshaw
- Organizer
  第85回日本遺伝学会年会
- Place of Presentation
  慶応大学（横浜）
- Data Source
  KAKENHI-PROJECT-25870487
[Presentation] プロテオミクスによる分裂期クロマチン制御構造の解析
- Author(s)
  太田信哉
- Organizer
  第32回染色体ワークショップ、第13回核ダイナミクス研究会
- Place of Presentation
  広島 (安芸グランドホテル)
- Year and Date
  2014-12-12 – 2014-12-14
- Data Source
  KAKENHI-PROJECT-25870487
[Presentation] 分裂期染色体上におけるタンパク質リン酸化の網羅的解析
- Author(s)
  太田信哉, 高木俊輔, 木村迪子, 石濱泰
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜 (パシフィコ横浜)
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25870487

1. 谷澤英樹 (70402550)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
2. 野間健一 (30900039)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. 木村宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 武田俊一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ohta Shinya 太田 信哉

太田 信哉 オオタ シンヤ

Research Projects

Research Products

Co-Researchers

染色体分離と転写を結び付ける分子機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

3Dゲノム構造を介した細胞老化に伴う遺伝子発現変容機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

分裂酵母とヒトの３Ｄゲノム構造とその形成機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel mechanism of pericentromere-specific heterochromatin formationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of novel centromere/kinetochore proteins in mitosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification and functional analysis of novel vertebrate chromosomal proteins with using Multi-Classifier Combinational ProteomicsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

多次元プロテオミクスを利用した新規染色体タンパク質の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Chemo-senolytic therapeutic potential against angiosarcoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Proteomics analysis understanding the regulation system of mitotic chromosome structure2018

Author(s)

Journal Title

Data Source

[Journal Article] Quantitative Proteomics of the Mitotic Chromosome Scaffold Reveals the Association of BAZ1B with Chromosomal Axes2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] HP1α targets the chromosomal passenger complex for activation at heterochromatin before mitotic entry.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nano Random Forests to mine protein complexes and their relationships in quantitative proteomics data.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of Mitosis-Specific Phosphorylation in Mitotic Chromosome-Associated Proteins.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Auxin/AID versus conventional knockouts: Distinguishing the roles of CENP-T/W in mitotic kinetochore assembly and stability2016

Author(s)

Journal Title

DOI

Ohta Shinya 太田信哉

太田信哉オオタシンヤ