Kajiya Mikihito 加治屋幹人

… Alternative Names

MIKIHITO Kajiya 加治屋幹人

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Researcher Number	00633041
Other IDs
Affiliation (Current)	2025: 広島大学, 病院(歯), 教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 広島大学, 病院(歯), 教授 2018 – 2021: 広島大学, 医系科学研究科(歯), 助教 2017 – 2019: 広島大学, 医歯薬保健学研究科(歯), 助教 2016: 広島大学, 病院(歯), 病院助教 2014 – 2015: 広島大学, 大学病院, 病院助教 2013: 広島大学, 大学病院, 助教 2012: 広島大学, 病院, 病院助教
Review Section/Research Field	Principal Investigator Periodontology / Basic Section 57040:Regenerative dentistry and dental engineering-related / Basic Section 57030:Conservative dentistry-related / Periodontal dentistry Except Principal Investigator Periodontology / Basic Section 57030:Conservative dentistry-related / Basic Section 57070:Developmental dentistry-related / Basic Section 57060:Surgical dentistry-related / Medium-sized Section 57:Oral science and related fields
Keywords	Principal Investigator 間葉系幹細胞集塊 / C-MSCs / C-MSC / 間葉系幹細胞 / 歯肉オルガノイド / 顎骨オルガノイド / 神経堤細胞由来間葉系幹細胞 / 歯周組織再生 / 他家移植 / 免疫原性 … More / 軟骨内骨化 / 軟骨誘導 / 骨再生 / 3D / メカノトランスダクション / YAP/TAZ / 組織再生 / ECM / MSC / 細胞治療 / スキャフォールドフリー / セメント芽細胞 / ERK / TrkB / BDNF / 再生医療 … More Except Principal Investigator マクロファージ / NR4A1 / 薬物性歯肉増殖症 / C-MSCs / 間葉系幹細胞集塊 / 侵襲性歯周炎 / ポリコーム群遺伝子 / エピゲノム / 顎顔面領域骨代謝性疾患 / シグナル伝達 / ポリコーム遺伝子 / 破骨細胞 / エピジェネティクス / がん微小環境 / 免疫回避 / 口腔扁平上皮癌 / YAP/TAZ / Hippo経路 / ダイオキシン受容体 / シグナルトランスダクション / 芳香族炭化水素受容体 / 口腔オルガノイド / シグナル伝達解析 / 口腔組織修復 / アリルハイドロカーボン受容体 / 創薬スクリーニング / Nr4a1 / ブチリデンフタリド / 立体複合化 / iPS細胞 / 神経堤細胞由来間葉系幹細胞 / 遺伝子改変マウス / 浸襲性歯周炎 / 歯学 / 歯肉増殖症 / メカニズム / ３Dプリンター / 3Dプリンター / 立体組織化 / 3Dバイオプリンター / 立体化 / C-MSC / 細胞集塊 / 間葉系幹細胞 / 凍結保存 / 免疫制御能 / 立体組織 / 歯周組織再生 / IL-6 / SAA / CRP / 血清アミロイド　A / グリチルリチン / 歯周炎 / マウス / 血糖値 / RAGE / HMGB1 / サイトカイン / Porphyromonas gulae / 糖尿病 / 歯周病 / ゲノム編集 / エクソームシークエンス / KIマウス / 原因遺伝子 Less

Deciphering the regulatory mechanism of cancer microenvironment induced by disruption of the Hippo pathway and novel therapeutic approach
- Principal Investigator
  
  安藤俊範
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Hiroshima University
Development of periodontal tissue regenerative allograft cell therapy by using clumps of MSCs and chondrogenic inductionPrincipal Investigator
- Principal Investigator
  
  加治屋幹人
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57040:Regenerative dentistry and dental engineering-related
- Research Institution
  Hiroshima University
Bone remodeling mechanism of epigenetic regulation for congenital anomaly in the ortho gnathic region.
- Principal Investigator
  
  井澤俊
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Okayama University
Challenge for analyzing the dysfunctional mechanism of oral barrier repair via dioxin receptor due to smoking
- Principal Investigator
  
  Izawa Takashi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Okayama University
Development of periodontal tissue regenerative allograft cell therapy by using clumps of MSCs and chondrogenic inductionPrincipal Investigator
- Principal Investigator
  
  Kajiya Mikihito
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Hiroshima University
To identify novel therapy drug of Drug induced gingival overgrowth targeting NR4A1 by drug screening
- Principal Investigator
  
  Shinji Matsuda
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Hiroshima University
Elucidation of the pathophysiology of aggressive periodontitis using MMD2 mutant mice
- Principal Investigator
  
  Mizuno Noriyoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Hiroshima University
Development of periodontal tissue regenerative therapy by using neural crest-derived MSCs and cell clumps culture technique
- Principal Investigator
  
  Kurihara Hidemi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Hiroshima University
Role of YAP/TAZ mechanotransduction in 3D culture clumps of MSCs/ECM complexesPrincipal Investigator
- Principal Investigator
  
  Kajiya Mikihito
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Periodontology
- Research Institution
  Hiroshima University
Research to develop new therapy targeting NR4A1 for drug-induced gingival overgrowth
- Principal Investigator
  
  Matsuda Shinji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  Hiroshima University
Identification of reated gene and pathologic analysis in familial aggressie periodontitis
- Principal Investigator
  
  Mizuno Noriyoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  Hiroshima University
Regulation of gingival epithelial cell's function suppresses systemic infection of periodontal pathogen.
- Principal Investigator
  
  Tsuyoshi Fujita
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  Hiroshima University
The development of periodontal regenerative cell therapy by using clumps of MSCs/ECM complexes
- Principal Investigator
  
  Hidemi Kuriha
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontology
- Research Institution
  Hiroshima University
Development of periodontal tissue regenerative therapy by using clumps of MSCs/ECM complexPrincipal Investigator
- Principal Investigator
  
  Mikihito Kajiya
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Periodontology
- Research Institution
  Hiroshima University
Development of novel periodontal tissue regenerative therapy by small molecule ligands induced TrkB transactivationPrincipal Investigator
- Principal Investigator
  
  MIKIHITO Kajiya
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Periodontal dentistry
- Research Institution
  Hiroshima University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013

All Journal Article Presentation Patent

[Journal Article] A Cartilaginous Construct with Bone Collar Exerts Bone-Regenerative Property Via Rapid Endochondral Ossification2023
- Author(s)
  Morimoto Shin、Kajiya Mikihito、Yoshii Hiroki、Yoshino Mai、Horikoshi Susumu、Motoike Souta、Iwata Tomoyuki、Ouhara Kazuhisa、Ando Toshinori、Yoshimoto Tetsuya、Shintani Tomoaki、Mizuno Noriyoshi
- Journal Title
  
  Stem Cell Reviews and Reports
  
  Volume: 19 Issue: 6 Pages: 1812-1827
- DOI
  10.1007/s12015-023-10554-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09983, KAKENHI-PROJECT-22K17060, KAKENHI-PROJECT-23K24533, KAKENHI-PROJECT-21K16993
[Journal Article] Distinctive Biological Properties between Mesenchymal Stem Cell Spheroids and Clumps of Mesenchymal Stem Cells/Extracellular Matrix Complexes in 3D Culture Systems2023
- Author(s)
  Yoshino Mai、Kajiya Mikihito、Yoshii Hiroki、Morimoto Shin、Horikoshi Susumu、Tari Misako、Iwata Tomoyuki、Ouhara Kazuhisa、Ando Toshinori、Yoshimoto Tetsuya、Shintani Tomoaki、Mizuno Noriyoshi
- Journal Title
  
  Applied Sciences
  
  Volume: 13 Issue: 23 Pages: 12790-12790
- DOI
  10.3390/app132312790
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K17060, KAKENHI-PROJECT-23K24533
[Journal Article] Xenotransplantation of cryopreserved human clumps of mesenchymal stem cells/extracellular matrix complexes pretreated with IFN-γ induces rat calvarial bone regeneration2022
- Author(s)
  Ogawa Tomoya、Kajiya Mikihito、Horikoshi Susumu、Yoshii Hiroki、Yoshino Mai、Motoike Souta、Morimoto Shin、Sone Hisakatsu、Iwata Tomoyuki、Ouhara Kazuhisa、Matsuda Shinji、Mizuno Noriyoshi
- Journal Title
  
  Regenerative Therapy
  
  Volume: 20 Pages: 117-125
- DOI
  10.1016/j.reth.2022.04.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10129, KAKENHI-PROJECT-22K09983, KAKENHI-PROJECT-22K17060, KAKENHI-PROJECT-20K09975, KAKENHI-PROJECT-21K21066
[Journal Article] Induction of functional xeno-free MSCs from human iPSCs via a neural crest cell lineage2022
- Author(s)
  Kamiya Daisuke、Takenaka-Ninagawa Nana、Motoike Souta、Kajiya Mikihito、Akaboshi Teppei、Zhao Chengzhu、Shibata Mitsuaki、Senda Sho、Toyooka Yayoi、Sakurai Hidetoshi、Kurihara Hidemi、Ikeya Makoto
- Journal Title
  
  npj Regenerative Medicine
  
  Volume: 7 Issue: 1 Pages: 47-47
- DOI
  10.1038/s41536-022-00241-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03803, KAKENHI-PROJECT-23K24533
[Journal Article] Clumps of mesenchymal stem cells/extracellular matrix complexes directly reconstruct the functional periodontal tissue in a rat periodontal defect model2022
- Author(s)
  Sone Hisakatsu、Kajiya Mikihito、Takeda Katsuhiro、Sasaki Shinya、Horikoshi Susumu、Motoike Souta、Morimoto Shin、Yoshii Hiroki、Yoshino Mai、Iwata Tomoyuki、Ouhara Kazuhisa、Matsuda Shinji、Mizuno Noriyoshi
- Journal Title
  
  Journal of Tissue Engineering and Regenerative Medicine
  
  Volume: 16 Issue: 10 Pages: 945-955
- DOI
  10.1002/term.3343
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09983, KAKENHI-PROJECT-22K17060, KAKENHI-PROJECT-20K09975, KAKENHI-PROJECT-21K21066, KAKENHI-PROJECT-23K24533
[Journal Article] The role of nuclear receptor 4A1 (NR4A1) in drug‐induced gingival overgrowth2021
- Author(s)
  Hatano Saki、Matsuda Shinji、Okanobu Ai、Furutama Daisuke、Memida Takumi、Kajiya Mikihito、Ouhara Kazuhisa、Fujita Tsuyoshi、Mizuno Noriyoshi、Kurihara Hidemi
- Journal Title
  
  The FASEB Journal
  
  Volume: 35 Issue: 7
- DOI
  10.1096/fj.202100032r
- Data Source
  KAKENHI-PROJECT-19K10130
[Journal Article] Clumps of Mesenchymal Stem Cells/Extracellular Matrix Complexes Generated with Xeno-Free Chondro-Inductive Medium Induce Bone Regeneration via Endochondral Ossification2021
- Author(s)
  Horikoshi Susumu、Kajiya Mikihito、Motoike Souta、Yoshino Mai、Morimoto Shin、Yoshii Hiroki、Ogawa Tomoya、Sone Hisakatsu、Iwata Tomoyuki、Ouhara Kazuhisa、Matsuda Shinji、Mizuno Noriyoshi、Kurihara Hidemi
- Journal Title
  
  Biomedicines
  
  Volume: 9 Issue: 10 Pages: 1408-1408
- DOI
  10.3390/biomedicines9101408
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10129, KAKENHI-PROJECT-21K21066
[Journal Article] Molecular Mechanisms of Periodontal Disease2021
- Author(s)
  Kajiya Mikihito、Kurihara Hidemi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 2 Pages: 930-930
- DOI
  10.3390/ijms22020930
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10129
[Journal Article] Optineurin regulates osteoblastogenesis through STAT12020
- Author(s)
  Mizuno Noriyoshi、Iwata Tomoyuki、Ohsawa Ryosuke、Ouhara Kazuhisa、Matsuda Shinji、Kajiya Mikihito、Matsuda Yukiko、Kume Kodai、Tada Yui、Morino Hiroyuki、Yoshimoto Tetsuya、Ueki Yasuyoshi、Mihara Keichiro、Sotomaru Yusuke
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 525(4) Issue: 4 Pages: 889-894
- DOI
  10.1016/j.bbrc.2020.03.028
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07994, KAKENHI-PROJECT-18H02978, KAKENHI-PROJECT-18K09599, KAKENHI-PROJECT-19K18999
[Journal Article] Cox2-mediated PGE2 production via p38/JNK-c-fos signaling inhibits cell apoptosis in 3D floating culture clumps of mesenchymal stem cell/extracellular matrix complexes2020
- Author(s)
  Komatsu Nao、Kajiya Mikihito、Morimoto Shin、Motoike Souta、Yoshii Hiroki、Iwata Tomoyuki、Ouhara Kazuhisa、Matsuda Shinji、Mizuno Noriyoshi、Kurihara Hidemi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 530 Issue: 2 Pages: 448-454
- DOI
  10.1016/j.bbrc.2020.05.100
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10129, KAKENHI-PROJECT-18H02977, KAKENHI-PROJECT-18K09599, KAKENHI-PROJECT-19K19030
[Journal Article] Aggressive periodontitis and NOD2 variants2020
- Author(s)
  Mizuno Noriyoshi, Kume Kodai, Nagatani Yukiko, Matsuda Shinji, Iwata Tomoyuki, Ouhara Kazuhisa, Kajiya Mikihito, Takeda Katsuhiro, Matsuda Yukiko, Tada Yui, Ohsawa Ryosuke, Morino Hiroyuki, Mihara Keichiro, Fujita Tsuyoshi, Kawaguchi Hiroyuki, Shiba Hideki, Kawakami Hideshi, Kurihara Hidemi
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 65(10) Issue: 10 Pages: 841-846
- DOI
  10.1038/s10038-020-0777-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07994, KAKENHI-PROJECT-18H02978, KAKENHI-PROJECT-18K09599
[Journal Article] Relationship between periodontal inflammation and calcium channel blockers induced gingival overgrowth?a cross-sectional study in a Japanese population2019
- Author(s)
  Matsuda Shinji、Okanobu Ai、Hatano Saki、Kajiya Mikihito、Sasaki Shinya、Hamamoto Yuta、Iwata Tomoyuki、Ouhara Kazuhisa、Takeda Katsuhiro、Mizuno Noriyoshi、Fujita Tsuyoshi、Kurihara Hidemi
- Journal Title
  
  Clinical Oral Investigations
  
  Volume: - Issue: 11 Pages: 4099-4105
- DOI
  10.1007/s00784-019-02846-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09599, KAKENHI-PROJECT-16K11830
[Journal Article] Clumps of Mesenchymal Stem Cell/Extracellular Matrix Complexes Generated with Xeno-Free Conditions Facilitate Bone Regeneration via Direct and Indirect Osteogenesis2019
- Author(s)
  Motoike Souta、Kajiya Mikihito、Komatsu Nao、Horikoshi Susumu、Ogawa Tomoya、Sone Hisakatsu、Matsuda Shinji、Ouhara Kazuhisa、Iwata Tomoyuki、Mizuno Noriyoshi、Fujita Tsuyoshi、Ikeya Makoto、Kurihara Hidemi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 16 Pages: 3970-3970
- DOI
  10.3390/ijms20163970
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09599, KAKENHI-PROJECT-19K10129, KAKENHI-PROJECT-19K19030, KAKENHI-PROJECT-18H02977, KAKENHI-PROJECT-18J13726
[Journal Article] Glycyrrhizic acid suppresses inflammation and reduces the increased glucose levels induced by the combination of Porphyromonas gulae and ligature placement in diabetic model mice2019
- Author(s)
  Akutagawa Keiichi、Fujita Tsuyoshi、Ouhara Kazuhisa、Takemura Tasuku、Tari Misako、Kajiya Mikihito、Matsuda Shinji、Kuramitsu Shohei、Mizuno Noriyoshi、Shiba Hideki、Kurihara Hidemi
- Journal Title
  
  International Immunopharmacology
  
  Volume: 68 Pages: 30-38
- DOI
  10.1016/j.intimp.2018.12.045
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09599, KAKENHI-PROJECT-18H02977
[Journal Article] Type I collagen deposition via osteoinduction ameliorates YAP/TAZ activity in 3D floating culture clumps of mesenchymal stem cell/extracellular matrix complexes2018
- Author(s)
  Komatsu Nao、Kajiya Mikihito、Motoike Souta、Takewaki Manabu、Horikoshi Susumu、Iwata Tomoyuki、Ouhara Kazuhisa、Takeda Katsuhiro、Matsuda Shinji、Fujita Tsuyoshi、Kurihara Hidemi
- Journal Title
  
  Stem Cell Research & Therapy
  
  Volume: 9 Issue: 1 Pages: 342-342
- DOI
  10.1186/s13287-018-1085-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09599, KAKENHI-PROJECT-17K17351
[Journal Article] Cryopreserved clumps of mesenchymal stem cell/extracellular matrix complexes retain osteogenic capacity and induce bone regeneration2018
- Author(s)
  Motoike Souta、Kajiya Mikihito、Komatsu Nao、Takewaki Manabu、Horikoshi Susumu、Matsuda Shinji、Ouhara Kazuhisa、Iwata Tomoyuki、Takeda Katsuhiro、Fujita Tsuyoshi、Kurihara Hidemi
- Journal Title
  
  Stem Cell Research & Therapy
  
  Volume: 9 Issue: 1 Pages: 73-73
- DOI
  10.1186/s13287-018-0826-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K17351, KAKENHI-PROJECT-15H05053, KAKENHI-PROJECT-15K11390, KAKENHI-PROJECT-18K09599, KAKENHI-PROJECT-18J13726
[Journal Article] Regulation of defensive function on gingival epithelial cells can prevent periodontal disease2018
- Author(s)
  Fujita　T., Yoshimoto T., Kajiya M., Ouhara K., Matsuda S., Takemura T., Akutagawa K., Takeda K., Mizuno N., Kurihara H.
- Journal Title
  
  Japanese Dental Science Review
  
  Volume: 印刷中 Issue: 2 Pages: 66-75
- DOI
  10.1016/j.jdsr.2017.11.003
- NAID
  50013109052
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K11389, KAKENHI-PROJECT-18K09599
[Journal Article] MSC/ECM cellular complexes induce periodontal tissue regeneration2017
- Author(s)
  Manabu Takewaki, Mikihito Kajiya*, Katsuhiro Takeda, Shinya Sasaki, Souta Motoike, Nao Komatsu, Shinji Matsuda, Kazuhisa Ouhara, Noriyoshi Mizuno, Tsuyoshi Fujita, and Hidemi Kurihara
- Journal Title
  
  Journal of Dental Research
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H05053
[Journal Article] Xenotransplantation of interferon-gamma-pretreated clumps of a human mesenchymal stem cell/extracellular matrix complex induces mouse calvarial bone regeneration2017
- Author(s)
  Kei Takeshita, Souta Motoike, Mikihito Kajiya, Nao Komatsu, Manabu Takewaki, Kazuhisa Ouhara, Tomoyuki Iwata, Katsuhiro Takeda, Noriyoshi Mizuno, Tsuyoshi Fujita, and Hidemi Kurihara
- Journal Title
  
  Stem Cell Research & Therapy
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H05053
[Journal Article] A novel gingival overgrowth mouse model induced by the combination of CsA and ligature-induced inflammation.2017
- Author(s)
  Okanobu A, Matsuda S, Kajiya M, Fujita T, Kittaka M, Shiba H, Kurihara H
- Journal Title
  
  Journal of Immunological Methods
  
  Volume: 印刷中 Pages: 31-36
- DOI
  10.1016/j.jim.2017.03.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11830
[Journal Article] Azithromycin recovers reductions in barrier function in human gingival epithelial cells stimulated with tumor necrosis factor-alfa2016
- Author(s)
  Miyagawa T., Fujita T., Yumoto H., Yoshimoto T., Kajiya M., Ouhara K., Matsuda S., Shiba H., Matsuo T., Kurihara H.
- Journal Title
  
  Arch Oral Biol.
  
  Volume: 62 Pages: 64-69
- DOI
  10.1016/j.archoralbio.2015.11.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K11389, KAKENHI-PROJECT-15K11390, KAKENHI-PROJECT-15K15766
[Journal Article] Clumps of a mesenchymal stromal cell/extracellular matrix complex can be a novel tissue engineering therapy for bone regeneration.2015
- Author(s)
  Kittaka M, Kajiya M, Shiba H, Takewaki M, Takeshita K, Khung R, Fujita T, Iwata T, Nguyen TQ, Ouhara K, Takeda K, Fujita T, Kurihara H.
- Journal Title
  
  Cytotherapy.
  
  Volume: 2 Issue: 7 Pages: 48-61
- DOI
  10.1016/j.jcyt.2015.01.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390467, KAKENHI-PROJECT-25862051, KAKENHI-PROJECT-26861814, KAKENHI-PROJECT-15H05053, KAKENHI-PROJECT-24593122
[Journal Article] BDNF mimetic compound LM22A-4 regulates cementoblast differentiation via the TrkB-ERK/Akt signaling cascade.2014
- Author(s)
  Kajiya M, Takeshita K, Kittaka M, Matsuda S, Ouhara K, Takeda K, Takata T, Kitagawa M, Fujita T, Shiba H, Kurihara H
- Journal Title
  
  Int Immunopharmacol
  
  Volume: 19(2) Issue: 2 Pages: 245-52
- DOI
  10.1016/j.intimp.2014.01.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890142
[Journal Article] BDNF mimetic compound LM22A-4 regulates cementoblast differentiation via the TrkB-ERK/AKt signaling cascade2014
- Author(s)
  Mikihito Kajiya, Kei Takeshita, Mizuho Kittaka, Shinji Matsuda, Kazuhisa Ouhara, Katsuhiro Takeda, Takashi Takata, Masae Kitagawa, Tsuyoshi Fujita, Hideki Shiba, and Hidemi Kurihara
- Journal Title
  
  International Immunopharmacology
  
  Volume: 19 Pages: 245-252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890142
[Patent] 凍結移植体及び凍結移植体の製造方法2016
- Inventor(s)
  栗原英見、加治屋幹人、本池総太
- Industrial Property Rights Holder
  広島大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-089188
- Filing Date
  2016-04-27
- Data Source
  KAKENHI-PROJECT-15H05053
[Presentation] Development of Bio-3D Printed Grafting Tissue for Periodontal Regeneration2024
- Author(s)
  Mikihito Kajiya, Hiroki Yoshii, Mai Yoshino, and Tetsuya Yoshimoto
- Organizer
  102nd General Session and Exhibition of the IADR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24533
[Presentation] Development of Periodontal Tissue Regenerative Therapy Using Mesenchymal Stem Cells and Bio-3D Printer2024
- Author(s)
  Mikihito Kajiya
- Organizer
  AADOCR-JSPS Joint Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24533
[Presentation] "New Avenues for Regenerative Medicine Opened by 3D Cell Clumps Culture Techniques and Nanodevices"2022
- Author(s)
  加治屋幹人
- Organizer
  生体医歯工学共同研究拠点第7回国際シンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24533
[Presentation] 薬物性歯肉増殖症におけるNR4A1 の役割2018
- Author(s)
  畑野　紗希，松田　真司，岡信　愛，加治屋　幹人，古玉　大祐，應原　一久，水野　智仁，
- Organizer
  第60回春季歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-16K11830
[Presentation] 絹糸結紮による実験的歯周炎マウスモデルにおける接合上皮の経時的変化について2017
- Author(s)
  竹村　翼，藤田　剛，松田真司，加治屋幹人，内田雄士，芥川桂一，應原一久，武田克浩，水野智仁，栗原英見
- Organizer
  第60回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-15K11389
[Presentation] ３次元培養間葉系幹細胞集塊の細胞分化を制御するメカノトランスダクション機構の解析2017
- Author(s)
  加治屋幹人、小松　奈央，本池　総太, 竹脇　学, 竹下　慶, 應原　一久, 武田　克浩, 岩田　倫幸, 藤田　剛,　栗原英見
- Organizer
  第16回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-15H05053
[Presentation] ３次元培養間葉系幹細胞集塊の細胞分化を制御するメカノトランスダクション機構の解析2017
- Author(s)
  加治屋幹人、小松　奈央，本池　総太, 竹脇　学, 竹下　慶, 應原　一久, 武田　克浩, 岩田　倫幸, 藤田　剛,　栗原英見
- Organizer
  第16回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-17K17351
[Presentation] Clumps of a mesenchymal stem cell/extracellular matrix complex induces periodontal tissue regeneration2017
- Author(s)
  竹脇学、加治屋幹人、武田克浩、佐々木慎也、本池総太、小松奈央、松田真司、應原一久、水野智仁、藤田　剛、栗原英見
- Organizer
  第12回アジア太平洋歯周病学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05053
[Presentation] 骨髄間葉系幹細胞集塊C-MSCによって拓く未来の歯周病細胞治療法2017
- Author(s)
  加治屋幹人
- Organizer
  第60回日本春季歯周病学会
- Invited
- Data Source
  KAKENHI-PROJECT-15H05053
[Presentation] 歯周病細胞治療における3次元培養法の現況と展望2017
- Author(s)
  加治屋幹人
- Organizer
  日本歯周病学会 60周年記念京都大会
- Invited
- Data Source
  KAKENHI-PROJECT-15H05053
[Presentation] ３次元培養される骨髄間葉系幹細胞集塊 Clumps of a MSC/ECM complexにおけるYAP/TAZシグナルの解析2017
- Author(s)
  小松奈央、加治屋　幹人,　本池　総太,　竹脇　学,　竹下　慶,　岩田　倫幸,　應原　一久,　武田　克浩,　藤田　剛,　栗原英見
- Organizer
  第95回国際歯科研究学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05053
[Presentation] 歯周病細胞治療における3次元培養法の現況と展望2017
- Author(s)
  加治屋幹人
- Organizer
  日本歯周病学会　60周年記念京都大会
- Data Source
  KAKENHI-PROJECT-17K17351
[Presentation] 骨髄間葉系幹細胞集塊C-MSCによって拓く未来の歯周病細胞治療2017
- Author(s)
  加治屋幹人
- Organizer
  第60回日本春季歯周病学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K17351
[Presentation] NR4A1を標的とした薬物性歯肉増殖症の新規治療法の開発2016
- Author(s)
  松田　真司、岡信愛、加治屋幹人、藤田　剛、栗原英見
- Organizer
  第32回歯科医学を中心とした総合的な研究を推進する集い
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-16K11830
[Presentation] 骨髄間葉系幹細胞集塊C-MSCを用いた新規細胞治療法の開発2016
- Author(s)
  加治屋幹人
- Organizer
  第59会春季日本歯周病学術大会
- Place of Presentation
  鹿児島市
- Year and Date
  2016-05-20
- Invited
- Data Source
  KAKENHI-PROJECT-15H05053
[Presentation] NR4A1に着目した薬物性歯肉増殖症のメカニズム解明の研究2016
- Author(s)
  岡信　愛、松田真司、加治屋幹人、藤田　剛、栗原英見
- Organizer
  第59回秋季歯周病学会学術大会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-16K11830
[Presentation] Elucidation of the role of NR4A1 in drug induced gingival overgrowth2016
- Author(s)
  岡信　愛、松田真司、加治屋幹人、藤田　剛、栗原英見
- Organizer
  第49回広島大学歯学会総会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-16K11830
[Presentation] NR4A1に着目した薬物性歯肉増殖症のメカニズム解明の研究2016
- Author(s)
  岡信　愛、松田真司、加治屋幹人、藤田　剛、栗原英見
- Organizer
  第58回歯科基礎医学会学術大会
- Place of Presentation
  北海道
- Data Source
  KAKENHI-PROJECT-16K11830
[Presentation] Clumps of MSCs/ECM complexを用いた新規歯周組織再生療法2016
- Author(s)
  竹脇学, 加治屋幹人, 竹下慶, 小松奈央, 岩田倫幸, 武田克浩, 應原一久, 藤田剛, 栗原英見
- Organizer
  第145回日本歯科保存学会2016年度秋季学術大会
- Place of Presentation
  松本市
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PROJECT-15H05053
[Presentation] 間葉系幹細胞と細胞外基質からなる細胞集塊を用いた新規の他家細胞移植療法の基礎研究2016
- Author(s)
  竹下慶，加治屋幹人, 竹脇学、小松奈央、本池総太、藤田剛、栗原英見
- Organizer
  第59回春季日本歯周病学会学術大会
- Place of Presentation
  鹿児島市
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-15H05053
[Presentation] 凍結保存が間葉系幹細胞集塊Clumps of MSCs/ECM complexによる骨再生に及ぼす影響2016
- Author(s)
  本池総太，加治屋幹人, 竹下慶、竹脇学、岩田倫幸、武田克浩、應原一久、藤田剛、栗原英見
- Organizer
  第59回春季日本歯周病学会学術大会
- Place of Presentation
  鹿児島市
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-15H05053
[Presentation] 骨髄間葉系幹細胞集塊Clumps of a MSC/ECM complex (C-MSC)におけるメカノトランスダクションの解析2016
- Author(s)
  小松奈央，加治屋幹人, 竹下慶, 竹脇学, 本池総太, 應原一久, 武田克浩, 岩田倫幸, 藤田剛,栗原英見
- Organizer
  第37回日本炎症・再生医学会
- Place of Presentation
  京都市
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-15H05053
[Presentation] 三次元培養で実現する有効・安全な組織再生技術の新展開2015
- Author(s)
  加治屋幹人
- Organizer
  日本組織培養学会第88回大会
- Place of Presentation
  広島
- Year and Date
  2015-05-26
- Invited
- Data Source
  KAKENHI-PROJECT-26861814
[Presentation] The development of immunomodulatory Clumps of a MSC/ECM complex for novel allograft cell transplantation therapy2015
- Author(s)
  竹下慶、　加治屋　幹人、竹脇　学、小松　奈央、應原　一久、岩田倫幸、藤田　剛、柴　秀樹、栗原　英見
- Organizer
  第58回春季歯周病学会
- Place of Presentation
  幕張メッセ（千葉県千葉市美浜区中瀬）
- Year and Date
  2015-05-14
- Data Source
  KAKENHI-PROJECT-15H05053
[Presentation] 三次元培養で実現する有効・安全な組織再生技術の新展開2015
- Author(s)
  加治屋幹人
- Organizer
  日本組織培養学会第88回大会
- Place of Presentation
  広仁会館（広島県広島市南区霞）
- Year and Date
  2015-05-26
- Invited
- Data Source
  KAKENHI-PROJECT-15H05053
[Presentation] 骨髄間葉系幹細胞集塊Clumps of mesenchymal stem cells/extracellular matrix complexを利用した新規組織再生療法開発2014
- Author(s)
  加治屋幹人
- Organizer
  第57回秋季日本歯周病学会学術大会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2014-10-19
- Data Source
  KAKENHI-PROJECT-26861814
[Presentation] Small Molecule BDNF mimetic regulates cementoblast differentiation via TrkB signaling2013
- Author(s)
  Mikihito Kajiya, Hideki Shiba, Kazuhisa Ouhara, Katsuhiro Takeda, Mizuho Kittaka, Takashi Takata, Masae Kitagawa, Hidemi Kurihara
- Organizer
  International Association of Dental Research
- Place of Presentation
  Seattle, USA
- Year and Date
  2013-03-20
- Data Source
  KAKENHI-PROJECT-24890142
[Presentation] 低分子BDNF模倣化合物LM22A-4はTrkBシグナルを介してセメント芽細胞の分化を制御する2013
- Author(s)
  加治屋幹人, 柏井　桂, 竹下　慶, Nguyen Quon Trung, 高田　隆, 北川雅恵, 藤田　剛, 柴　秀樹, 栗原英見
- Organizer
  日本歯科保存学会　2013年度春季学術大会（138回）
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24890142
[Presentation] 低分子BDNF模倣化合物LM22A-4はTrkBシグナルを介してセメント芽細胞の分化を制御する2013
- Author(s)
  加治屋幹人、柏井圭、竹下慶、Nguyen Quoc Troung、高田隆、北川雅恵、藤田剛、柴秀樹、栗原英見
- Organizer
  日本歯科保存学会2013年度春季学術大会(第139回)
- Place of Presentation
  福岡、日本
- Year and Date
  2013-06-27
- Data Source
  KAKENHI-PROJECT-24890142
[Presentation] Small molecule BDNF mimetic regulates cementoblast differentiation via TrkB signaling2013
- Author(s)
  Mikihito Kajiya
- Organizer
  International Association of Dental Research
- Place of Presentation
  USA Seattle
- Data Source
  KAKENHI-PROJECT-24890142

1. Tsuyoshi Fujita (80379883)

# of Collaborated Projects: 5 results

# of Collaborated Products: 23 results
2. Mizuno Noriyoshi (60325181)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
3. Matsuda Shinji (30611321)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
4. Hidemi Kuriha (40161765)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
5. 岩田倫幸 (30418793)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
6. Izawa Takashi (30380017)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 川上秀史 (70253060)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 加藤功一 (50283875)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 池谷真 (20442923)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
10. 早野暁 (20633712)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 安藤俊範 (40754552)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 五島悠介 (00710576)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 柳本惣市 (10315260)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 泉大樹 (80813485)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 後藤健彦 (10274127)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 太田耕司 (20335681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 上岡寛 (80253219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. MIYAGAWA TSUYOSHI

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. IMAI HARUKA

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. YOSHIMOTO TETSUYA

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
21. AKUTAGAWA KEIICHI

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
22. TAKEMURA TASUKU

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
23. Komatsu Nao

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
24. MORINO Hiroyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
25. 應原一久

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
26. 趙成珠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 松田由喜子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
28. 堀越励

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kajiya Mikihito 加治屋 幹人

MIKIHITO Kajiya 加治屋 幹人

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Development of periodontal tissue regenerative allograft cell therapy by using clumps of MSCs and chondrogenic inductionPrincipal Investigator

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Development of periodontal tissue regenerative allograft cell therapy by using clumps of MSCs and chondrogenic inductionPrincipal Investigator

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Role of YAP/TAZ mechanotransduction in 3D culture clumps of MSCs/ECM complexesPrincipal Investigator

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Development of periodontal tissue regenerative therapy by using clumps of MSCs/ECM complexPrincipal Investigator

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Development of novel periodontal tissue regenerative therapy by small molecule ligands induced TrkB transactivationPrincipal Investigator

Kajiya Mikihito 加治屋幹人

MIKIHITO Kajiya 加治屋幹人