Sugimoto Nozomi 杉本のぞみ

… Alternative Names

SUGIMOTO Nozomi 杉本のぞみ

Less

Researcher Number	00633108
Other IDs	https://orcid.org/0000-0002-4313-5728
Affiliation (based on the past Project Information) *help	2018 – 2020: 九州大学, 薬学研究院, 助教 2016: 九州大学, 薬学研究院, 助教 2013 – 2015: 九州大学, 薬学研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Tumor biology / Biological pharmacy
Keywords	Principal Investigator p53 / GRWD1 / がん / MDM2 / Purα / RPs / RPL22 / FAIRE / TCGA / p21 … More / RPS17 / p53反応性プロモーター / RPL11 / 発がん / 転写 / ChIP / 次世代シーケンサー / Pura Less

Comprehensive analysis of p53 negative regulation by novel oncogene GRWD1Principal Investigator
- Principal Investigator
  
  Sugimoto Nozomi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kyushu University
Novel histone chaperone GRWD1 inhibits p53 and promotes tumorigenesisPrincipal Investigator
- Principal Investigator
  
  Sugimoto Nozomi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Kyushu University
Elucidation of transcription regulation mechanism by Pura and novel histone chaperone GRWD1Principal Investigator
- Principal Investigator
  
  SUGIMOTO Nozomi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyushu University

All 2020 2019 2018 2016 2015 2013 Other

All Journal Article Presentation

[Journal Article] SLX4-XPF mediates DNA damage responses to replication stress induced by DNA-protein interactions2020
- Author(s)
  Riko Ishimoto, Yota Tsuzuki, Tomoki Matsumura, Seiichiro Kurashige, Koyuki Enokitani, Koki Narimatsu, Mitsunori Higa, Nozomi Sugimoto, Kazumasa Yoshida, Masatoshi Fujita
- Journal Title
  
  Journal of Cell Biology
  
  Volume: 220 Issue: 1
- DOI
  10.1083/jcb.202003148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07201
[Journal Article] GRWD1 directly interacts with p53 and negatively regulates p53 transcriptional activity.2020
- Author(s)
  Fujiyama H., Tsuji T., Hironaka K., Yoshida K., Sugimoto N. and Fujita M.
- Journal Title
  
  Journal of Biochemistry
  
  Volume: 167 Issue: 1 Pages: 15-24
- DOI
  10.1093/jb/mvz075
- NAID
  40022134096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07201
[Journal Article] Inhibiting the MCM8-9 complex selectively sensitizes cancer cells to cisplatin and olaparib.2019
- Author(s)
  Morii, I., Iwabuchi, Y., Mori, S., Suekuni, M., Natsume, T., Yoshida, K., Sugimoto, N., Kanemaki, MT. and Fujita, M.
- Journal Title
  
  Cancer Science
  
  Volume: 110 Issue: 3 Pages: 1044-1053
- DOI
  10.1111/cas.13941
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07201, KAKENHI-PROJECT-17K15065, KAKENHI-PROJECT-17K15068
[Journal Article] Identification of candidate molecular targets of the novel antineoplastic antimitotic NP-10.2019
- Author(s)
  Yokoyama T., Yukuhiro M., Iwasaki Y., Tanaka C., Sankoda K., Fujiwara R., Shibuta A., Higashi T., Motoyama K., Arima H., Yoshida K., Sugimoto N., Morimoto H., Kosako H., Ohshima T. and Fujita M.
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1
- DOI
  10.1038/s41598-019-53259-2
- NAID
  120006875663
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07201, KAKENHI-PLANNED-15H05846, KAKENHI-PROJECT-17H03972
[Journal Article] Glutamate-rich WD40 repeat containing 1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.2018
- Author(s)
  Watanabe, S., Fujiyama, H., Takafuji, T., Kayama, K., Matsumoto, M., Nakayama, KI., Yoshida, K., Sugimoto, N. (Corresponding author), and Fujita, M.
- Journal Title
  
  Journal of Cell Science
  
  Volume: 131 Issue: 15 Pages: 213009-213009
- DOI
  10.1242/jcs.213009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07201, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-17H05534, KAKENHI-PLANNED-17H06301, KAKENHI-PROJECT-18H04000, KAKENHI-PROJECT-18J20791
[Journal Article] Cdt1-binding protein GRWD1 is a novel histone-binding protein that facilitates MCM loading through its influence on chromatin architecture.2015
- Author(s)
  Sugimoto N, Maehara K, Yoshida K, Yasukouchi S, Osano S, Watanabe S, Aizawa M, Yugawa T, et al.
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 43 Issue: 12 Pages: 5898-5911
- DOI
  10.1093/nar/gkv509
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460406, KAKENHI-PROJECT-15K18412, KAKENHI-PLANNED-25116010, KAKENHI-PUBLICLY-26114713, KAKENHI-PROJECT-25291027, KAKENHI-PROJECT-26290064
[Presentation] Elucidation of tumor-suppressive mechanism of Ribosomal protein S17 associated with cancer-prone ribosomopathiks2020
- Author(s)
  Yukino Mori, Takuya Takefuji, Kazumasa Yoshida, Nozomi Sugimoto, Thru Kiyono, Masatoshi Fujita
- Organizer
  第79回日本癌学会
- Data Source
  KAKENHI-PROJECT-18K07201
[Presentation] TRF2にリクルートされたORC複合体は複製ストレス下でのテロメア安定性に寄与している.2019
- Author(s)
  比嘉允宣, 松田侑大, 杉本のぞみ, 吉田和真, 藤田雅俊
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K07201
[Presentation] DNA複製開始におけるクロマチン構造変換メカニズムの解明.2019
- Author(s)
  辻田沙伎, 岩村拓人, 會澤誠大, 吉田和真, 杉本のぞみ, 藤田雅俊
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K07201
[Presentation] Systematic elucidation of mechanisms underlying formation of licensed chromatin in human cells.2019
- Author(s)
  Nozomi Sugimoto, Nari Fujita, Saki Tsujita, Takuto Iwamura, Kazumitsu Maehara, Kazumasa Yoshida, Yasuyuki Ohkawa, Masatoshi Fujita
- Organizer
  第92回日本生化学会大会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18K07201
[Presentation] がん選択的分裂期停止作用を持つ新規化合物NP-10の作用機序の解明.2019
- Author(s)
  三小田一成、横山拓哉、行弘政樹、吉田和真、杉本のぞみ、森本浩之、大嶋孝志、小迫英尊、藤田雅俊
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K07201
[Presentation] ORC1フラグメントによる競合阻害を用いたテロメア複製におけるTRF2-ORC1結合の生物的意義の解明.2019
- Author(s)
  松田侑大, 比嘉允宣, 杉本のぞみ, 吉田和真, 藤田雅俊
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K07201
[Presentation] Systematic elucidation of mechanisms underlying formation of licensed chromatin in human cells.2019
- Author(s)
  Nozomi Sugimoto, Nari Fujita, Saki Tsujita, Takuto Iwamura, Kazumitsu Maehara, Kazumasa Yoshida, Yasuyuki Ohkawa, Masatoshi Fujita
- Organizer
  第42回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07201
[Presentation] ORC1フラグメントによる競合阻害を用いたテロメア複製におけるTRF2-ORC1結合の生物的意義の解明.2019
- Author(s)
  松田侑大, 比嘉允宣, 杉本のぞみ, 吉田和真, 藤田雅俊
- Organizer
  第25回DNA複製・組換え・修復ワークショップ
- Data Source
  KAKENHI-PROJECT-18K07201
[Presentation] ヒト染色体上のlacO-LacI複合体に対する複製ストレス応答機構のSLX4-ヌクレアーゼ複合体に着目した解析.2019
- Author(s)
  松村友輝, 都築洋太, 石本理子, 杉本のぞみ, 吉田和真, 藤田雅俊
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K07201
[Presentation] ヒト染色体上の強固な"DNA-タンパク質"複合体が誘導する複製ストレス応答と染色体異常の解析.2019
- Author(s)
  吉田和真, 杉本のぞみ, 藤田雅俊
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K07201
[Presentation] 複製ストレス：その原因、帰結、そしてがん治療への応用.2019
- Author(s)
  Masatoshi Fujita, Nozomi Sugimoto, Kazumasa Yoshida
- Organizer
  第42回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07201
[Presentation] pre-RC形成時のクロマチン構造制御のゲノムワイド解析.2019
- Author(s)
  藤田成, 吉田和真, 前原一満, 大川恭行, 杉本のぞみ, 藤田雅俊
- Organizer
  第25回DNA複製・組換え・修復ワークショップ
- Data Source
  KAKENHI-PROJECT-18K07201
[Presentation] リボソームタンパク質による細胞がん化制御機構の包括的解明.2019
- Author(s)
  高藤拓哉, 藤山拓己, 筒井夏佳, 森優希乃, 吉田和真, 杉本のぞみ, 小迫英尊, 藤田雅俊
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K07201
[Presentation] 高発がん性リボソーム病関連タンパク質RPS7によるがん抑制機構の解明.2019
- Author(s)
  筒井夏佳, 高藤拓哉, 森優希乃, 吉田和真, 杉本のぞみ, 藤田雅俊
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K07201
[Presentation] pre-RC形成時のクロマチン構造制御のゲノムワイド解析.2019
- Author(s)
  藤田成, 吉田和真, 前原一満, 大川恭行, 杉本のぞみ, 藤田雅俊
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K07201
[Presentation] GRWD1はp53と直接相互作用してp53の転写活性化能を抑制する.2019
- Author(s)
  藤山拓己, 都地崇拡, 廣中研介, 吉田和真, 杉本のぞみ, 藤田雅俊
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K07201
[Presentation] Molecular mechanisms by which GRWD1 down regulates p53 to transform cells.2018
- Author(s)
  杉本のぞみ
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07201
[Presentation] ヒト細胞におけるpre-RC形成とfiringの時空間的制御のゲノムワイド解析2016
- Author(s)
  杉本のぞみら
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K18412
[Presentation] Genome-wide analysis for spatiotemporal regulation of the pre-RC formation and firing in human cells2015
- Author(s)
  杉本のぞみ、他
- Organizer
  BMB2015
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2015-12-03
- Invited
- Data Source
  KAKENHI-PROJECT-15K18412
[Presentation] ヒト細胞における複製前複合体(pre-RC)形成とfiringの時空間的制御のゲノムワイド解析2015
- Author(s)
  杉本のぞみ、他
- Organizer
  第23回DNA複製・組換え・修復ワークショップ
- Place of Presentation
  静岡県焼津市
- Year and Date
  2015-10-20
- Data Source
  KAKENHI-PROJECT-15K18412
[Presentation] Genome-wide analysis for spatiotemporal regulation of the pre-RC formation and firing in human cells.2015
- Author(s)
  Sugimoto, N. et al.
- Organizer
  Eukaryotic DNA replication & Genome maintenance on Cold Spring Harbor Laboratory Meeting
- Place of Presentation
  Cold Spring Harbor, USA
- Year and Date
  2015-09-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18412
[Presentation] Genome-scale analysis for spatiotemporal regulation of the pre-RC formation and firing in human cells.2015
- Author(s)
  Sugimoto, N. et al.
- Organizer
  International Symposium on Non-Coding DNA and Chromosomal Integrity
- Place of Presentation
  兵庫県淡路市
- Year and Date
  2015-08-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18412
[Presentation] Cdt1 binding protein GRWD1 is a novel histone chaperone that regulates chromatin structure and MCM loading2013
- Author(s)
  Nozomi Sugimoto, et al.
- Organizer
  Cold Spring Harbor Laboratory Meeting on "Eukaryotic DNA replication & Genome Maintenance"
- Place of Presentation
  Cold Spring Harbor, NY, USA
- Data Source
  KAKENHI-PROJECT-25870509
[Presentation] Cdt1結合蛋白質GRWD1はクロマチン構造およびMCMローディングを制御する新規ヒストンシャペロンである2013
- Author(s)
  杉本のぞみ et al.
- Organizer
  第65回細胞生物学会・シンポジウム
- Place of Presentation
  愛知県名古屋市(ウインクあいち)
- Invited
- Data Source
  KAKENHI-PROJECT-25870509
[Presentation] Cdt1 結合蛋白質 GRWD1 は新規ヒストンシャペロンでありクロマチン構造と MCM 結合を制御している2013
- Author(s)
  杉本のぞみ et al.
- Organizer
  第36回日本分子生物学会年会・ワークショップ
- Place of Presentation
  兵庫県神戸市(神戸ポートアイランド)
- Invited
- Data Source
  KAKENHI-PROJECT-25870509
[Presentation] 新規ヒストンシャペロンGRWD1はゲノムワイドにクロマチン制御を行い複製ライセンシングを促進する
- Author(s)
  杉本のぞみ et al.
- Organizer
  第37会日本分子生物学会年会
- Place of Presentation
  神奈川県横浜市 (パシフィコ横浜)
- Year and Date
  2014-11-25 – 2014-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-25870509

1. 温川恭至

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sugimoto Nozomi 杉本 のぞみ

SUGIMOTO Nozomi 杉本 のぞみ

Research Projects

Research Products

Co-Researchers

Comprehensive analysis of p53 negative regulation by novel oncogene GRWD1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel histone chaperone GRWD1 inhibits p53 and promotes tumorigenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of transcription regulation mechanism by Pura and novel histone chaperone GRWD1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] SLX4-XPF mediates DNA damage responses to replication stress induced by DNA-protein interactions2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] GRWD1 directly interacts with p53 and negatively regulates p53 transcriptional activity.2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Inhibiting the MCM8-9 complex selectively sensitizes cancer cells to cisplatin and olaparib.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of candidate molecular targets of the novel antineoplastic antimitotic NP-10.2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Glutamate-rich WD40 repeat containing 1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cdt1-binding protein GRWD1 is a novel histone-binding protein that facilitates MCM loading through its influence on chromatin architecture.2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] Elucidation of tumor-suppressive mechanism of Ribosomal protein S17 associated with cancer-prone ribosomopathiks2020

Author(s)

Organizer

Data Source

[Presentation] TRF2にリクルートされたORC複合体は複製ストレス下でのテロメア安定性に寄与している.2019

Author(s)

Organizer

Data Source

[Presentation] DNA複製開始におけるクロマチン構造変換メカニズムの解明.2019

Author(s)

Organizer

Data Source

[Presentation] Systematic elucidation of mechanisms underlying formation of licensed chromatin in human cells.2019

Author(s)

Organizer

Data Source

[Presentation] がん選択的分裂期停止作用を持つ新規化合物NP-10の作用機序の解明.2019

Author(s)

Organizer

Data Source

[Presentation] ORC1フラグメントによる競合阻害を用いたテロメア複製におけるTRF2-ORC1結合の生物的意義の解明.2019

Author(s)

Organizer

Data Source

[Presentation] Systematic elucidation of mechanisms underlying formation of licensed chromatin in human cells.2019

Sugimoto Nozomi 杉本のぞみ

SUGIMOTO Nozomi 杉本のぞみ