ICHINOSE Wataru 一ノ瀬亘

Researcher Number	00636409
Affiliation (based on the past Project Information) *help	2019: 北海道大学, 薬学研究科(研究院), 特別研究員 2016: 北海道大学, 薬学研究院, 特別研究員(PD) 2015: 北海道大学, 薬学研究科(研究院), 特別研究員 2015: 北海道大学, 薬学研究科(研究院), 特別研究員(PD) 2014: 東北大学, 大学院薬学研究科, 研究助教 2013 – 2014: 北海道大学, 薬学研究科(研究院), 研究員
Review Section/Research Field	Principal Investigator Drug development chemistry / Chemical pharmacy Except Principal Investigator Drug development chemistry / Chemical pharmacy
Keywords	Principal Investigator バーチャルスクリーニング / リード化合物 / ライブラリー合成 / 計算化学 / ペプチドミメティック / ナノ粒子 / ゲル収縮 / アミドヘリセン / エチニルヘリセン / マルチドメイン … More / 伸縮ゲル / 二重ラセン / アミドオリゴマー / ヘリセン / スイッチ / 伸縮 / 平衡移動 / シリカナノ粒子 / 有機ゲル / ヘリセンオリゴマー … More Except Principal Investigator ペプチドミイメティクス / ライブラリー / ペプチドミメティクス / ヌクレオシド / レゾルビン / 三次元多様性 / シクロプロパン / 均一系 / 不均一系反応場 / 有機合成 / 触媒 / リン / イオウ / 遷移金属 / ナノ粒子 / 平衡移動 / 有機合成化学 / ヘテロ元素化合物 / 省エネルギー / 非平衡熱力学系 / 平衡制御 / 遷移金属触媒 / 有機ヘテロ元素化合物 Less

The efficient transformation from cyclic peptide to lead ligandPrincipal Investigator
- Principal Investigator
  
  ICHINOSE Wataru
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Hokkaido University
Medicinal chemistry studies based on the three-dimensional structural diversity-oriented molecular design of pharmacologically active compounds
- Principal Investigator
  
  Shuto Satoshi
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Drug development chemistry
- Research Institution
  Hokkaido University
Synthesis and Composed Functions of Multidomain Oligomers with Double-helix StructurePrincipal Investigator
- Principal Investigator
  
  ICHINOSE Wataru
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Hokkaido University
Development and Efficient Production of Organosulfur and Organophosphorus Compounds by Transition Metal Catalyzed Method
- Principal Investigator
  
  YAMAGUCHI Masahiko
- Project Period (FY)
  2009 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Tohoku University

All 2019 2018 2017 2014 2013 2012

All Journal Article Presentation

[Journal Article] Development of a Highly Potent Analogue and a Long-Acting Analogue of Oxytocin for the Treatment of Social Impairment-Like Behaviors2019
- Author(s)
  Ichinose W, Cherepanov SM, Shabalova AA, Yokoyama S, Yuhi T, Yamaguchi H, Watanabe A, Yamamoto Y, Okamoto H, Horike S, Terakawa J, Daikoku T, Watanabe M, Mano N, Higashida H, Shuto S
- Journal Title
  
  J Med Chem
  
  Volume: - Issue: 7 Pages: 3297-3310
- DOI
  10.1021/acs.jmedchem.8b01691
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06889, KAKENHI-PROJECT-15H02495, KAKENHI-PROJECT-18K06742, KAKENHI-PROJECT-19K06965, KAKENHI-PROJECT-19H01014, KAKENHI-PROJECT-19H00388
[Journal Article] Structure-specific Effects of Lipidated Oxytocin Analogs on Intracellular Calcium Levels, Parental Behavior, Plasma and Cerebrospinal Fluid Oxytocin Concentrations in Mice.2017
- Author(s)
  S. M. Cherepanov, S. Yokoyama, A. Mizuno, W. Ichinose, O. Lopatina, A. A. Shabalova, A. B. Salmina, Y. Yamamoto, H. Okamoto, S. Shuto, H. Higashida
- Journal Title
  
  Pharmacol. Res. Perspect.
  
  Volume: 5 Issue: 1 Pages: 1-14
- DOI
  10.1002/prp2.290
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02495
[Journal Article] Reversible Shrinkage of Self-Assembled Two-Component Organogels by Lithium Salts : Synthesis of Gelation Property and Lithium Salt Response Using Bidomain Helicene Oligomer2014
- Author(s)
  W. Ichinose, M. Miyagawa, M. Yamaguchi
- Journal Title
  
  Chemistry of Materials
  
  Volume: 25 Issue: 20 Pages: 4036-4043
- DOI
  10.1021/cm4024869
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J07469, KAKENHI-PROJECT-25860002
[Journal Article] Equilibrium Shift in Solution: Molecular Shape Recognition and Precipitation of a Synthetic Double Helix Using Helicene-Grafted Silica Nanoparticles2014
- Author(s)
  Masamichi Miyagawa, Wataru Ichinose, Masahiko Yamaguchi
- Journal Title
  
  Chemistry A European Journal
  
  Volume: 20 Pages: 1272-1278
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860002
[Journal Article] Tetrameric ααββ Aggregate Formation by Stereoisomeric Bidomain Helicene Oligomers2013
- Author(s)
  Wataru Ichinose, Jun Ito, Masahiko Yamaguchi
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 52 Issue: 20 Pages: 5290-5294
- DOI
  10.1002/anie.201301463
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860002
[Journal Article] Opitical Resolution of Aromatic Alcohols Using Silica Nanoparticles Grafted with Helicene2012
- Author(s)
  W. Ichinose, M. Miyagawa, Z. An, M. Yamaguchi
- Journal Title
  
  Org. Lett.,
  
  Volume: 14 Issue: 12 Pages: 3123-3125
- DOI
  10.1021/ol301206r
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229001
[Presentation] trans-1, 2-シクロプロパンジアミンおよびジカルボン酸からなるオリゴアミドの合成研究2018
- Author(s)
  山田圭恭, 一ノ瀬亘, 福田隼, 渡邉瑞貴, 周東智
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15H02495
[Presentation] Synthesis and evaluation of novel “scrambled” peptoids2017
- Author(s)
  Wataru Ichinose, Harry R. King, Paul W. Denny, Steven L. Cobb
- Organizer
  RSC Organic Division North East Regional Meeting
- Place of Presentation
  Durham, United Kingdom
- Year and Date
  2017-03-29
- Data Source
  KAKENHI-PROJECT-15K18897
[Presentation] シクロプロパンの立体及び立体電子特性に基づくペプチドミメティクス2017
- Author(s)
  桑原智希，植村真衣，水野彰，一ノ瀬亘，松井耕平，福田隼，渡邉瑞貴，周東智
- Organizer
  第43回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-15H02495

1. YAMAGUCHI Masahiko (30158117)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. AN Zenjian (80532176)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. SHIGENO Masanori (30571921)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. SAITO Nozomi (40636411)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. LI Guanzou (90714824)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Shuto Satoshi (70241346)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. 小松康雄 (30271670)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 福田隼 (30434450)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 有澤光弘 (40312962)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 山口浩明 (80400373)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 山本靖彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ICHINOSE Wataru 一ノ瀬 亘

Research Projects

Research Products

Co-Researchers

The efficient transformation from cyclic peptide to lead ligandPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Medicinal chemistry studies based on the three-dimensional structural diversity-oriented molecular design of pharmacologically active compounds

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Synthesis and Composed Functions of Multidomain Oligomers with Double-helix StructurePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development and Efficient Production of Organosulfur and Organophosphorus Compounds by Transition Metal Catalyzed Method

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Development of a Highly Potent Analogue and a Long-Acting Analogue of Oxytocin for the Treatment of Social Impairment-Like Behaviors2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structure-specific Effects of Lipidated Oxytocin Analogs on Intracellular Calcium Levels, Parental Behavior, Plasma and Cerebrospinal Fluid Oxytocin Concentrations in Mice.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reversible Shrinkage of Self-Assembled Two-Component Organogels by Lithium Salts : Synthesis of Gelation Property and Lithium Salt Response Using Bidomain Helicene Oligomer2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Equilibrium Shift in Solution: Molecular Shape Recognition and Precipitation of a Synthetic Double Helix Using Helicene-Grafted Silica Nanoparticles2014

Author(s)

Journal Title

Data Source

[Journal Article] Tetrameric ααββ Aggregate Formation by Stereoisomeric Bidomain Helicene Oligomers2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Opitical Resolution of Aromatic Alcohols Using Silica Nanoparticles Grafted with Helicene2012

Author(s)

Journal Title

DOI

Data Source

[Presentation] trans-1, 2-シクロプロパンジアミンおよびジカルボン酸からなるオリゴアミドの合成研究2018

Author(s)

Organizer

Data Source

[Presentation] Synthesis and evaluation of novel “scrambled” peptoids2017

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] シクロプロパンの立体及び立体電子特性に基づくペプチドミメティクス2017

Author(s)

Organizer

Data Source

ICHINOSE Wataru 一ノ瀬亘