Yamashita Akihiro 山下晃弘

… Alternative Names

Akihiro Yamashita 山下晃弘

YAMASHITA Akihiro 山下晃弘

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Researcher Number	00636855
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2022 – 2024: 大阪大学, 大学院医学系研究科, 助教 2020 – 2021: 大阪大学, 医学系研究科, 助教 2018 – 2019: 京都大学, iPS細胞研究所, 特定拠点助教 2016: 京都大学, iPS細胞研究所, 特定拠点助教 2015: 京都大学, iPS細胞研究所, 助教 2012 – 2014: 京都大学, iPS細胞研究所, 研究員
Review Section/Research Field	Principal Investigator Basic Section 56020:Orthopedics-related / Surgical dentistry / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords	Principal Investigator iPS細胞 / 再生医学 / 骨・軟骨代謝学 / 幹細胞 / 軟骨 / 遺伝子改変 / 骨代謝学 / 再生医療 / 遺伝子治療 / 再生医療学 … More / 幹細胞学 / 軟骨代謝学 / 軟骨周膜 / 軟骨膜 / 軟骨再生 / 再生 / 骨軟骨代謝学 / 骨・軟骨代謝 / 創薬 / FGFR3 / 骨系統疾患 / 骨軟骨分化 / 疾患 Less

遺伝子治療による新規軟骨再生法開発を目指した基盤の構築　ーiPS軟骨を利用してーPrincipal Investigator
- Principal Investigator
  
  山下晃弘
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Osaka University
ヒト3次元軟骨組織モデルによる新規軟骨特異的分子の同定と軟骨分化制御機構の解明Principal Investigator
- Principal Investigator
  
  山下晃弘
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Osaka University
Elucidation of the function of cartilage membrane using iPSC-derived cartilagePrincipal Investigator
- Principal Investigator
  
  Akihiro Yamashita
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Osaka University
  Kyoto University
Elucidation of disease mechanism and therapy of FGFR3 skeletal dysplasia using patient-derived iPSCsPrincipal Investigator
- Principal Investigator
  
  Yamashita Akihiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Kyoto University
Disease modeling and drug screening of thanatophooric dysplasia using reprogramming technologyPrincipal Investigator
- Principal Investigator
  
  YAMASHITA Akihiro
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Surgical dentistry
- Research Institution
  Kyoto University

All 2024 2023 2022 2021 2020 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] Engraftment of allogeneic iPS cell-derived cartilage organoid in a primate model of articular cartilage defect2023
- Author(s)
  Abe Kengo、Yamashita Akihiro、Morioka Miho、Horike Nanao、Takei Yoshiaki、Koyamatsu Saeko、Okita Keisuke、Matsuda Shuichi、Tsumaki Noriyuki
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 804-804
- DOI
  10.1038/s41467-023-36408-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02923, KAKENHI-PROJECT-20K09432, KAKENHI-PROJECT-23K21466, KAKENHI-PROJECT-23K18327, KAKENHI-PROJECT-23K27720
[Journal Article] Generation of Monkey Induced Pluripotent Stem Cell-Derived Cartilage Lacking Major Histocompatibility Complex Class I Molecules on the Cell Surface2022
- Author(s)
  Okutani Yuki、Abe Kengo、Yamashita Akihiro、Morioka Miho、Matsuda Shuichi、Tsumaki Noriyuki
- Journal Title
  
  Tissue Engineering Part A
  
  Volume: 28 Issue: 1-2 Pages: 94-106
- DOI
  10.1089/ten.tea.2021.0053
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02924, KAKENHI-PROJECT-23K21466
[Journal Article] Human pluripotent stem cell-derived cartilaginous organoids promote scaffold-free healing of critical size long bone defects2021
- Author(s)
  Tam Wai Long、Freitas Mendes Luis、Chen Xike、Lesage Raphaelle、Van Hoven Inge、Leysen Elke、Kerckhofs Greet、Bosmans Kathleen、Chai Yoke Chin、Yamashita Akihiro、Tsumaki Noriyuki、Geris Liesbet、Roberts Scott J.、Luyten Frank P.
- Journal Title
  
  Stem Cell Research & Therapy
  
  Volume: 12 Issue: 1 Pages: 513-528
- DOI
  10.1186/s13287-021-02580-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02924, KAKENHI-PROJECT-18H02923, KAKENHI-PROJECT-23K21466
[Journal Article] Recent progress of animal transplantation studies for treating articular cartilage damage using pluripotent stem cells2021
- Author(s)
  Yamashita Akihiro、Tsumaki Noriyuki
- Journal Title
  
  Development, Growth & Differentiation
  
  Volume: 63 Issue: 1 Pages: 72-81
- DOI
  10.1111/dgd.12706
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02924
[Journal Article] Culture substrate‐associated YAP inactivation underlies chondrogenic differentiation of human induced pluripotent stem cells2020
- Author(s)
  Yamashita Akihiro、Yoshitomi Hiroyuki、Kihara Shunsuke、Toguchida Junya、Tsumaki Noriyuki
- Journal Title
  
  STEM CELLS Translational Medicine
  
  Volume: 10 Issue: 1 Pages: 115-127
- DOI
  10.1002/sctm.20-0058
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02923, KAKENHI-PROJECT-18H02929, KAKENHI-PROJECT-18H02924
[Journal Article] Quality assessment tests for tumorigenicity of human iPS cell-derived cartilage2020
- Author(s)
  Takei Yoshiaki、Morioka Miho、Yamashita Akihiro、Kobayashi Tomohito、Shima Nobuyuki、Tsumaki Noriyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 12794-12805
- DOI
  10.1038/s41598-020-69641-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02923, KAKENHI-PROJECT-18H02924
[Journal Article] Integration Capacity of Human Induced Pluripotent Stem Cell-Derived Cartilage.2018
- Author(s)
  Chen X, Yamashita A, Morioka M, Senba T, Kamatani T, Watanabe A, Kosai A, Tsumaki N.
- Journal Title
  
  Tissue Eng Part A,
  
  Volume: 25 Issue: 5-6 Pages: 437-445
- DOI
  10.1089/ten.tea.2018.0133
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0108, KAKENHI-PROJECT-18H02923, KAKENHI-PROJECT-18H02924, KAKENHI-PROJECT-18H02826
[Journal Article] Considerations in hiPSC-derived cartilage for articular cartilage repair.2018
- Author(s)
  Yamashita A, Tamamura Y, Morioka M, Karagiannis P, Shima N, Tsumaki N
- Journal Title
  
  Inflamm Regen.
  
  Volume: 38 Issue: 1 Pages: 1-7
- DOI
  10.1186/s41232-018-0075-8
- NAID
  120006937645
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11636, KAKENHI-PROJECT-18H02923, KAKENHI-PROJECT-18H02924
[Journal Article] Limited immunogenicity of human iPS cell-derived cartilage2016
- Author(s)
  Kimura T, Yamashita A, Ozono K, Tsumaki N
- Journal Title
  
  Tissue Eng Part A
  
  Volume: 22 Pages: 1367-1367
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861716
[Journal Article] Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3.2016
- Author(s)
  Yahara Y, Takemori H, Okada M, Kosai A, Yamashita A, Kobayashi T, Fujita K, Itoh Y, Nakamura M, Fuchino H, Kawahara N, Fukui N, Watanabe A, Kimura T, Tsumaki N.
- Journal Title
  
  Nat Commun
  
  Volume: 7 Issue: 1 Pages: 10959-10959
- DOI
  10.1038/ncomms10959
- NAID
  120005741112
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861716, KAKENHI-PROJECT-15H02561, KAKENHI-PROJECT-15K15546
[Journal Article] iPS細胞を用いた軟骨疾患に対する再生医療開発2016
- Author(s)
  山下晃弘、妻木範行
- Journal Title
  
  月刊糖尿病
  
  Volume: 8 Pages: 91-91
- Data Source
  KAKENHI-PROJECT-26861716
[Journal Article] iPS cell technologies and cartilage regeneration2015
- Author(s)
  Tsumaki N, Okada M, Yamashita A
- Journal Title
  
  Bone
  
  Volume: 70 Pages: 48-54
- DOI
  10.1016/j.bone.2014.07.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390354, KAKENHI-PROJECT-26861716
[Journal Article] Modeling type II collagenopathy skeletal dysplasia by directed conversion and induced pluripotent stem cells2015
- Author(s)
  Okada M, Ikegawa S, Morioka M, Yamashita A, Saito A, Sawai H,Murotsuki J, Ohashi H, Okamoto T, Nishimura G, Imaizumi K, Tsumaki N
- Journal Title
  
  Hum Mol Genet
  
  Volume: 24 Issue: 2 Pages: 299-313
- DOI
  10.1093/hmg/ddu444
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390354, KAKENHI-PROJECT-25251014, KAKENHI-PROJECT-26861716
[Journal Article] Generation of Scaffoldless Hyaline Cartilaginous Tissue from Human iPSCs2015
- Author(s)
  Yamashita, A., Morioka, M., Yahara, Y., Okada, M., Kobayashi, T., Kuriyama, S., Matsuda, S., and Tsumaki, N
- Journal Title
  
  Stem cell reports
  
  Volume: 4 Issue: 3 Pages: 404-418
- DOI
  10.1016/j.stemcr.2015.01.016
- NAID
  120005767006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390354, KAKENHI-PROJECT-26861716
[Journal Article] Statin treatment rescues FGFR3 skeletal dysplasia phenotypes2014
- Author(s)
  Yamashita A, Morioka M, Kishi H, Kimura T, Yahara Y, Okada M, Fujita,K, Sawai H, Ikegawa S, Tsumaki N.
- Journal Title
  
  Nature
  
  Volume: 513(7519) Issue: 7519 Pages: 507-11
- DOI
  10.1038/nature13775
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390354, KAKENHI-PROJECT-26861716
[Journal Article] iPS細胞由来軟骨細胞を用いた再生治療開発2013
- Author(s)
  山下晃弘、妻木範行
- Journal Title
  
  Phama Medica
  
  Volume: 31巻4号(招待論文) Pages: 29-32
- Data Source
  KAKENHI-PROJECT-24890101
[Journal Article] Embryonic stem cells incorporate into newly formed bone and do not form tumors in an immunocompetent mouse fracture model2013
- Author(s)
  Taiani JT, Krawetz RJ, Yamashita A, Pauchard Y, Buie HR, Ponjevic D, Boyd SK, Rancourt DE, Matyas JR
- Journal Title
  
  Cell Transplant
  
  Volume: 22(8) Issue: 8 Pages: 1453-62
- DOI
  10.3727/096368912x658755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890101
[Journal Article] iPS細胞を使うー軟骨の研究へ2013
- Author(s)
  妻木範行、岡田稔、山下晃弘
- Journal Title
  
  整形外科
  
  Volume: 64巻10号(招待論文) Pages: 1106-1109
- Data Source
  KAKENHI-PROJECT-24890101
[Journal Article] Direct induction of chondrogenic cells from human dermal fibroblast culture by defined factors2013
- Author(s)
  Outani H, Okada M, Yamashita A, Nakagawa K, Yoshikawa H, Tsumaki N.
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 10 Pages: e77365-e77365
- DOI
  10.1371/journal.pone.0077365
- NAID
  120005333915
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390354, KAKENHI-PROJECT-24890101
[Journal Article] Cartilage tissue engineering identifies abnormal human induced pluripotent stem cells2013
- Author(s)
  Yamashita A, Liu S, Woltjen K, Thomas B, Meng G, Hotta A, Takahashi K, Ellis J, Yamanaka S, Rancourt DE
- Journal Title
  
  Sci Rep
  
  Volume: 3 Issue: 1 Pages: 1978-1978
- DOI
  10.1038/srep01978
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890101
[Journal Article] iPS細胞由来軟骨細胞を用いた再生治療開発2013
- Author(s)
  山下晃弘, 妻木範行
- Journal Title
  
  Pharma Medica
  
  Volume: 31(4) Pages: 29-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890101
[Journal Article] iPS細胞由来軟骨細胞を用いた再生治療開発2013
- Author(s)
  山下晃弘
- Journal Title
  
  Pharma Medica
  
  Volume: in press
- Data Source
  KAKENHI-PROJECT-24890101
[Journal Article] Expansion and long term maintenance of induced pluripotent stem cells in stirred suspension bioreactors2012
- Author(s)
  Shafa M, Sjonnesen K, Yamashita A, Liu S, Michalak M, Kallos MS, Rancourt DE
- Journal Title
  
  J of Tissue. Eng. Regen. Med
  
  Volume: 6(6) Issue: 6 Pages: 462-72
- DOI
  10.1002/term.450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890101
[Journal Article] Derivation of iPSCs in stirred suspension bioreactors2012
- Author(s)
  Shafa M, Day B, Yamashita A, Meng G, Liu S, Krawetz R, Rancourt DE
- Journal Title
  
  Nat Methods
  
  Volume: 9(5) Issue: 5 Pages: 465-6
- DOI
  10.1038/nmeth.1973
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890101
[Presentation] 内軟骨性骨化におけるCrispld1の機能解明2024
- Author(s)
  山下晃弘, 妻木範行
- Organizer
  第36回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-23K21466
[Presentation] Application of iPS cell technologies to treat skeletal disease2020
- Author(s)
  Yamashita A, Tsumaki N
- Organizer
  第68回国際歯科研究学会日本部会 (JADR) 総会・学術大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02924
[Presentation] ヒトiPS細胞由来軟骨を用いた限局した関節軟骨治療法の開発2020
- Author(s)
  山下晃弘, 妻木範行
- Organizer
  第38回日本骨代謝学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02924
[Presentation] フィーダーフリーiPS細胞から移植用軟骨の作成2017
- Author(s)
  山下晃弘, 森岡美帆、小林与人、奥谷祐希、栗山新一、小屋松冴子、矢島伸之、島伸行、松田秀一、妻木範行
- Organizer
  軟骨代謝学会
- Place of Presentation
  京都
- Year and Date
  2017-03-03
- Data Source
  KAKENHI-PROJECT-26861716
[Presentation] ヒトiPS細胞由来軟骨を用いた関節軟骨再生治療の試み2016
- Author(s)
  山下晃弘, 妻木範行
- Organizer
  日本炎症・再生医学会
- Place of Presentation
  京都
- Year and Date
  2016-06-16
- Invited
- Data Source
  KAKENHI-PROJECT-26861716
[Presentation] ヒトiPS細胞由来軟骨の開発2016
- Author(s)
  山下晃弘, 妻木範行
- Organizer
  骨代謝学会
- Place of Presentation
  大阪
- Year and Date
  2016-07-21
- Invited
- Data Source
  KAKENHI-PROJECT-26861716
[Presentation] iPS細胞技術を用いた軟骨疾患治療方法の開発2016
- Author(s)
  山下晃弘
- Organizer
  立命館大学　細胞工学特論
- Place of Presentation
  滋賀
- Year and Date
  2016-01-13
- Invited
- Data Source
  KAKENHI-PROJECT-26861716
[Presentation] Regenerative treatment of focal defects of articular cartilage with iPS cell-derived cartilage2016
- Author(s)
  Yamashita A, Tsumaki N
- Organizer
  APLAR
- Place of Presentation
  上海
- Year and Date
  2016-09-27
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861716
[Presentation] スタチンによるFGFR3軟骨形成異常症の病態回復2016
- Author(s)
  山下晃弘、森岡美帆、岸宏美、木村武司、箭原康人、岡田稔、藤田香里、澤井英明、池川志郎、妻木範行
- Organizer
  軟骨代謝学会
- Place of Presentation
  広島
- Year and Date
  2016-02-19
- Invited
- Data Source
  KAKENHI-PROJECT-26861716
[Presentation] iPS細胞を使った軟骨疾患治療法の開発2015
- Author(s)
  山下晃弘
- Organizer
  第３回労災医療研修会
- Place of Presentation
  大阪府医師会館
- Year and Date
  2015-02-20
- Invited
- Data Source
  KAKENHI-PROJECT-26861716
[Presentation] iPS細胞疾患モデルを用いたFGFR3軟骨形成異常症の研究2015
- Author(s)
  山下晃弘、妻木範行
- Organizer
  骨代謝学会
- Place of Presentation
  東京
- Year and Date
  2015-07-23
- Invited
- Data Source
  KAKENHI-PROJECT-26861716
[Presentation] スタチンによるFGFR3軟骨形成異常症の病態回復 – iPS細胞疾患モデルを用いて–2015
- Author(s)
  山下晃弘、妻木範行。
- Organizer
  第30回日本整形外科学会基礎学術集会
- Place of Presentation
  富山
- Year and Date
  2015-10-22
- Invited
- Data Source
  KAKENHI-PROJECT-26861716
[Presentation] スタチンによるFGFR3病の病態改善　ー疾患特異的iPS細胞を用いてー2014
- Author(s)
  山下晃弘
- Organizer
  第17回日本骨代謝研究会
- Place of Presentation
  慶応義塾大学
- Year and Date
  2014-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-26861716
[Presentation] Abnormal chondrogenic differentiation of induced pluripotent stem cells established from patients with a severe skeletal disease, thanatophoric dysplasia2014
- Author(s)
  Yamashita A, Tsumaki N
- Organizer
  Takeda symposium
- Place of Presentation
  Takeda symposium
- Data Source
  KAKENHI-PROJECT-24890101
[Presentation] Abnormal chondrogenic differentiation of induced pluripotent stem cells established from patients with a severe skeletal disease, thanatophoric dysplasia2014
- Author(s)
  Yamashita A, Tsumaki N
- Organizer
  Takeda symposium
- Place of Presentation
  Osaka, Japan
- Data Source
  KAKENHI-PROJECT-24890101
[Presentation] Derivation of transplantable cartilage from human induced pluripotent stem cells2014
- Author(s)
  Yamashita A, Morioka M, Yahara Y, Okada M, Tsumaki N
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-24890101
[Presentation] ヒトiPS細胞を用いた致死性骨異形成症の病態解明2013
- Author(s)
  山下晃弘, 妻木範行
- Organizer
  日本炎症・再生学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24890101
[Presentation] Modeling and rescue of abnormal chondrogenic differentiation of induced pluripotent stem cells with a severe skeletal disease, thanatophoric dysplasia2013
- Author(s)
  A Yamashita
- Organizer
  CiRA retreat 13
- Place of Presentation
  滋賀
- Data Source
  KAKENHI-PROJECT-24890101
[Presentation] ヒトiPS細胞から軟骨細胞への分化におけるGDF5の効果2013
- Author(s)
  山下晃弘,妻木範行
- Organizer
  BMP研究会
- Place of Presentation
  浜松
- Year and Date
  2013-07-05
- Data Source
  KAKENHI-PROJECT-24890101
[Presentation] ヒトiPS細胞から軟骨細胞への分化誘導2013
- Author(s)
  山下晃弘,妻木範行
- Organizer
  ORC研究会
- Place of Presentation
  かずさ
- Data Source
  KAKENHI-PROJECT-24890101
[Presentation] ヒトiPS細胞から軟骨細胞への分化誘導2013
- Author(s)
  山下晃弘, 妻木範行
- Organizer
  ORC研究会
- Place of Presentation
  茨城
- Data Source
  KAKENHI-PROJECT-24890101
[Presentation] ヒトiPS細胞を用いた致死性骨異形成症の病態解明2013
- Author(s)
  山下晃弘,妻木範行
- Organizer
  日本炎症・再生学会
- Place of Presentation
  京都(優秀演題賞受賞)
- Data Source
  KAKENHI-PROJECT-24890101
[Presentation] Abnormal chondrogenic differentiation of induced pluripotent stem cells with a severe skeletal disease, thanatophoric dysplasia2013
- Author(s)
  Yamashita A, Tsumaki N
- Organizer
  CiRA International Symposium 2013 Raising the Next Generation of Stem Cell Research
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-24890101
[Presentation] The activation of c-MYC and LIN28B causes iPSC tumor formation during in vitro cartilage differentiation2012
- Author(s)
  Yamashita A, Thomas B, Rancourt DE
- Organizer
  10^<th> Annual Meeting of the International Society for Stem Cell Research
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-24890101
[Presentation] ヒトiPS細胞から軟骨細胞への分化におけるGDF5の効果
- Author(s)
  山下晃弘, 妻木範行
- Organizer
  BMP研究会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-24890101
[Presentation] ヒトiPS細胞から硝子軟骨様組織への分化誘導法の確立
- Author(s)
  山下晃弘, 森岡美帆、箭原康人、岡田稔、小田直純、妻木範行
- Organizer
  軟骨代謝学会
- Place of Presentation
  東京
- Year and Date
  2015-03-06 – 2015-03-07
- Data Source
  KAKENHI-PROJECT-26861716
[Presentation] Statin treatment rescues FGFR3 skeletal dysplasia phenotypes
- Author(s)
  Yamashita A, Morioka M, Kishi H, Kimura T, Yahara Y, Okada M, Fujita K, Sawai H, Ikegawa S, Tsumaki N.
- Organizer
  Takeda symposium
- Place of Presentation
  Osaka
- Year and Date
  2015-01-15 – 2015-01-17
- Data Source
  KAKENHI-PROJECT-26861716
[Presentation] ヒトiPS細胞を用いた移植可能な軟骨様組織の作成
- Author(s)
  山下晃弘, 森岡美帆、箭原康人、岡田稔、妻木範行
- Organizer
  再生医療学会
- Place of Presentation
  横浜
- Year and Date
  2015-03-19 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-26861716
[Presentation] ヒトiPS細胞から軟骨細胞への分化誘導
- Author(s)
  山下晃弘, 妻木範行
- Organizer
  日本骨代謝学会
- Place of Presentation
  大阪
- Year and Date
  2014-07-24 – 2014-07-26
- Invited
- Data Source
  KAKENHI-PROJECT-26861716

1. WATANABE Akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. TAMAMURA Yoshihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 妻木範行

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results

Yamashita Akihiro 山下 晃弘

Akihiro Yamashita 山下 晃弘

YAMASHITA Akihiro 山下 晃弘

Research Projects

Research Products

Co-Researchers

遺伝子治療による新規軟骨再生法開発を目指した基盤の構築 ーiPS軟骨を利用してーPrincipal Investigator

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ヒト3次元軟骨組織モデルによる新規軟骨特異的分子の同定と軟骨分化制御機構の解明Principal Investigator

Principal Investigator

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Elucidation of the function of cartilage membrane using iPSC-derived cartilagePrincipal Investigator

Principal Investigator

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Elucidation of disease mechanism and therapy of FGFR3 skeletal dysplasia using patient-derived iPSCsPrincipal Investigator

Principal Investigator

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Disease modeling and drug screening of thanatophooric dysplasia using reprogramming technologyPrincipal Investigator

Principal Investigator

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[Journal Article] Engraftment of allogeneic iPS cell-derived cartilage organoid in a primate model of articular cartilage defect2023

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[Journal Article] Generation of Monkey Induced Pluripotent Stem Cell-Derived Cartilage Lacking Major Histocompatibility Complex Class I Molecules on the Cell Surface2022

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[Journal Article] Human pluripotent stem cell-derived cartilaginous organoids promote scaffold-free healing of critical size long bone defects2021

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[Journal Article] Recent progress of animal transplantation studies for treating articular cartilage damage using pluripotent stem cells2021

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[Journal Article] Culture substrate‐associated YAP inactivation underlies chondrogenic differentiation of human induced pluripotent stem cells2020

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[Journal Article] Quality assessment tests for tumorigenicity of human iPS cell-derived cartilage2020

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[Journal Article] Integration Capacity of Human Induced Pluripotent Stem Cell-Derived Cartilage.2018

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[Journal Article] Considerations in hiPSC-derived cartilage for articular cartilage repair.2018

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NAID

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[Journal Article] Limited immunogenicity of human iPS cell-derived cartilage2016

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Yamashita Akihiro 山下晃弘

Akihiro Yamashita 山下晃弘

YAMASHITA Akihiro 山下晃弘

遺伝子治療による新規軟骨再生法開発を目指した基盤の構築　ーiPS軟骨を利用してーPrincipal Investigator