Fukuda Kyoko 福田恭子

… Alternative Names

張エイ

ZHANG Rong 張エイ

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Researcher Number	00643719
Affiliation (Current)	2025: 千葉大学, 大学院医学研究院, 特任研究員
Affiliation (based on the past Project Information) *help	2015 – 2024: 国立研究開発法人国立がん研究センター, 先端医療開発センター, 研究員 2014: 愛知県がんセンター(研究所), その他部局等, その他 2013 – 2014: 愛知県がんセンター(研究所), 腫瘍免疫学部, リサーチレジデント
Review Section/Research Field	Principal Investigator Respiratory surgery / Basic Section 55040:Respiratory surgery-related Except Principal Investigator Basic Section 55020:Digestive surgery-related / Digestive surgery
Keywords	Principal Investigator がん / 免疫 / 人工多能性幹細胞 / インターフェロン / 外科 / 細胞療法 / iPS細胞 / 1型インターフェロン / ミエロイド細胞 / 免疫療法 … More / がん免疫療法 / 癌 / 遺伝子治療 / 遺伝子療法 / 肺がん … More Except Principal Investigator 免疫 / がん / 免疫療法 / キメラ抗原受容体 / 人工多能性幹細胞 / 細胞療法 / 外科 / 免疫制御 / 樹状細胞 / iNKT細胞 / NKT細胞 / がん免疫療法 / 再生医療 / 再生免疫学 / 膵臓 Less

Development of novel chimeric antigen receptor (CAR) macrophage therapy for solid tumors
- Principal Investigator
  
  植村靖史
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  National Cancer Center Japan
Cell preparation regulating the in vivo function of CAR-T cells
- Principal Investigator
  
  Uemura Yasushi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  National Cancer Center Japan
Therapy for lung cancer using the genetically engineered myeloid cells producing type III IFNPrincipal Investigator
- Principal Investigator
  
  Fukuda Kyoko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  National Cancer Center Japan
Generation of tumor-reactive T cells from iPS cell-derived NKT cells and application for pancreatic cancer therapy
- Principal Investigator
  
  Uemura Yasushi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  National Cancer Center Japan
Type I IFN-producing myeloid cells as a cell preparation for lung canerPrincipal Investigator
- Principal Investigator
  
  Fukuda Kyoko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  National Cancer Center Japan
Reprogramming and re-differentiation of invariant NKT cells for pancreatic cancer immunotherapy
- Principal Investigator
  
  UEMURA Yasushi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  National Cancer Center Japan
Application of anti-cancer effector cells that exert adjuvant effects for lung cancerPrincipal Investigator
- Principal Investigator
  
  ZHANG Rong
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory surgery
- Research Institution
  Aichi Cancer Center Research Institute

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Book

[Book] 実験医学増刊2020
- Author(s)
  福田恭子, 植村靖史
- Total Pages
  7
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-20K09186
[Journal Article] Immune cell therapy against disseminated melanoma by utilizing induced pluripotent stem cell-derived myeloid cell lines producing interferon-beta or interleukin-15/interleukin-15 receptor alpha2021
- Author(s)
  Mizuhashi S, Kubo Y, Fukushima S, Kanemaru H, Nakahara S, Miyasita A, Ishibashi T, Kuriyama H, Kimura T, Masuguchi S, Zhang R, Iwama T, Nakatsura T, Uemura Y, Senju S, Ihn H.
- Journal Title
  
  J Dermatol Sci.
  
  Volume: - Issue: 2 Pages: 133-136
- DOI
  10.1016/j.jdermsci.2021.03.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08301, KAKENHI-PROJECT-20K17353, KAKENHI-PROJECT-20K22850, KAKENHI-PROJECT-20K09186
[Journal Article] CD11b + DIP2A + LAG3 + cells facilitate immune dysfunction in colorectal cancer2021
- Author(s)
  Kudo-Saito C, Ogiwara Y, Imazeki H, Boku N, Uemura Y, Zhang R, Kawano-Nagatsuma A, Kojima M, Ochiai A.
- Journal Title
  
  Am J Cancer Res.
  
  Volume: 11 Pages: 5428-5439
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09186
[Journal Article] Immunotherapy with 4-1BBL-Expressing iPS Cell-Derived Myeloid Lines Amplifies Antigen-Specific T Cell Infiltration in Advanced Melanoma2021
- Author(s)
  Kuriyama H, Fukushima S, Kimura T, Kanemaru H, Miyashita A, Okada E, Kubo Y, Nakahara S, Tokuzumi A, Nishimura Y, Kajihara I, Makino K, Aoi J, Masuguchi S, Tsukamoto H, Inozume T, Zhang R, Nakatsura T, Uemura Y, Senju S, Ihn H.
- Journal Title
  
  Int J Mol Sci .
  
  Volume: 22(4) Issue: 4 Pages: 1958-1958
- DOI
  10.3390/ijms22041958
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09186, KAKENHI-PROJECT-18K07325, KAKENHI-PROJECT-18K08301, KAKENHI-PROJECT-20K17353, KAKENHI-PROJECT-20K22850
[Journal Article] Improved safety of induced pluripotent stem cell-derived antigen-presenting cell-based cancer immunotherapy2021
- Author(s)
  Mashima H, Zhang R, Kobayashi T, Tsukamoto H, Liu T, Iwama T, Hagiya Y, Yamamoto M, Fukushima S, Okada S, Idiris A, Kaneko S, Nakatsura T, Ohdan H, Uemura Y.
- Journal Title
  
  Mol Ther Methods Clin Dev .
  
  Volume: 21 Pages: 171-179
- DOI
  10.1016/j.omtm.2021.03.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08301, KAKENHI-PROJECT-18H02641, KAKENHI-PROJECT-20K09186
[Journal Article] Analysis of human glioma-associated co-inhibitory immune checkpoints in glioma microenvironment and peripheral blood2021
- Author(s)
  Shen S, Wu Q, Liu J, Wu L, Zhang R, Uemura Y, Yu X, Chen L, Liu T.
- Journal Title
  
  Int J Immunopathol Pharmacol.
  
  Volume: 35 Pages: 1-10
- DOI
  10.1177/20587384211056505
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09186
[Journal Article] Induced pluripotent stem cell‐derived myeloid cells expressing OX40 ligand amplify antigen‐specific T cells in advanced melanoma2020
- Author(s)
  Kimura Toshihiro、Fukushima Satoshi、Okada Etsuko、Miyashita Azusa、Tsukamoto Hirotake、Uemura Yasushi、Senju Satoru、Ihn Hironobu
- Journal Title
  
  Pigment Cell & Melanoma Research
  
  Volume: - Issue: 5 Pages: 744-755
- DOI
  10.1111/pcmr.12887
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16345, KAKENHI-PROJECT-19K21328, KAKENHI-PROJECT-20K09186, KAKENHI-PROJECT-20K22850, KAKENHI-PLANNED-16H06498, KAKENHI-PROJECT-18K07325, KAKENHI-PROJECT-18K08301
[Journal Article] Current state and future of co-inhibitory immune checkpoints for the treatment of glioblastoma.2020
- Author(s)
  Shen S, Chen L, Liu J, Yang L, Zhang M, Wang L, Zhang R, Uemura Y, Wu Q, Yu X, Liu T.
- Journal Title
  
  Cancer Bio Med.
  
  Volume: 17(3) Issue: 3 Pages: 555-568
- DOI
  10.20892/j.issn.2095-3941.2020.0027
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09186
[Journal Article] Generation of GM-CSF-producing antigen-presenting cells that induce a cytotoxic T cell-mediated antitumor response.2020
- Author(s)
  Mashima H, Zhang R, Kobayashi T, Hagiya Y, Tsukamoto H, Liu T, Iwama T, Yamamoto M, Lin C, Nakatsuka R, Mishima Y, Watanabe N, Yamada T, Senju S, Kaneko S, Idiris A, Nakatsura T, Ohdan H, Uemura Y.
- Journal Title
  
  Oncoimmunology
  
  Volume: 9(1) Issue: 1 Pages: 1814620-1814620
- DOI
  10.1080/2162402x.2020.1814620
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09186, KAKENHI-PROJECT-20K16439, KAKENHI-PROJECT-18K07325
[Journal Article] In Vitro Detection of Cellular Adjuvant Properties of Human Invariant Natural Killer T Cells2019
- Author(s)
  Zhang Rong、Kitayama Shuichi、Liu Tianyi、Ueda Norihiro、Tokumitsu Yumi、Mashima Hiroaki、Ohdan Hideki、Kaneko Shin、Uemura Yasushi
- Journal Title
  
  Methods Mol Biol
  
  Volume: 2048 Pages: 121-130
- DOI
  10.1007/978-1-4939-9728-2_13
- ISBN
  9781493997275, 9781493997282
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H02082, KAKENHI-PROJECT-17K10717, KAKENHI-PROJECT-17K10806
[Journal Article] Type I Interferon Delivery by iPSC-Derived Myeloid Cells Elicits Antitumor Immunity via XCR1+ Dendritic Cells.2019
- Author(s)
  Tsuchiya N, Zhang R, Iwama T, Ueda N, Liu T, Tatsumi M, Sasaki Y, Shimoda R, Osako Y, Sawada Y, Kubo Y, Miyashita A, Fukushima S, Cheng Z, Nakaki R, Takubo K, Okada S, Kaneko S, Ihn H, Kaisho T, Nishimura Y, Senju S, Endo I, Nakatsura T, Uemura Y.
- Journal Title
  
  Cell Rep.
  
  Volume: 29 Issue: 1 Pages: 162-175
- DOI
  10.1016/j.celrep.2019.08.086
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08301, KAKENHI-PUBLICLY-19H04813, KAKENHI-PROJECT-17H04088, KAKENHI-PROJECT-18H02845, KAKENHI-PROJECT-17K10717, KAKENHI-PROJECT-17K10806, KAKENHI-PROJECT-18K19570, KAKENHI-PROJECT-17K16345, KAKENHI-PROJECT-18H02641, KAKENHI-PLANNED-16H06498
[Journal Article] Enhancing T cell Receptor Stability in Rejuvenated iPSC-derived T cells improves their use in cancer immunotherapy2018
- Author(s)
  Minagawa A, Yoshikawa T, Yasukawa M, Hotta A, Kunitomo M, Iriguchi S, Takiguchi M, Kassai Y, Imai E, Yasui Y, Kawai Y, Zhang R, Uemura Y, Miyoshi H, Nakanishi M, Watanabe A, Hayashi A, Kawana K, Fujii T, Nakatsura T, Kaneko S
- Journal Title
  
  Cell Stem Cell
  
  Volume: 23 Issue: 6 Pages: 850-858
- DOI
  10.1016/j.stem.2018.10.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10717, KAKENHI-PROJECT-17K10806, KAKENHI-PROJECT-17KT0108, KAKENHI-PROJECT-18K07301, KAKENHI-PROJECT-18K16085, KAKENHI-PROJECT-16H05194, KAKENHI-PROJECT-15K06900, KAKENHI-PROJECT-18H02839, KAKENHI-PROJECT-18H02641, KAKENHI-PROJECT-18H02826
[Journal Article] Generation of TCR-Expressing Innate Lymphoid-like Helper Cells that Induce Cytotoxic T Cell-Mediated Anti-leukemic Cell Response.2018
- Author(s)
  Ueda N, Uemura Y, Zhang R, Kitayama S, Iriguchi S, Kawai Y, Yasui Y, Tatsumi M, Ueda T, Liu TY, Mizoro Y, Okada C, Watanabe A, Nakanishi M, Senju S, Nishimura Y, Kuzushima K, Kiyoi H, Naoe T, Kaneko S
- Journal Title
  
  Stem Cell Reports
  
  Volume: 10 Issue: 6 Pages: 1935-1946
- DOI
  10.1016/j.stemcr.2018.04.025
- NAID
  120006473765
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-17K10717, KAKENHI-PROJECT-17K10806, KAKENHI-PROJECT-17KT0108, KAKENHI-PLANNED-16H06498, KAKENHI-PROJECT-16H05194, KAKENHI-PROJECT-17K07238, KAKENHI-PROJECT-18H02641, KAKENHI-PROJECT-18H02826
[Journal Article] Co-delivery of tumor-derived exosomes with alpha-galactosylceramide on dendritic cell-based immunotherapy for glioblastoma2017
- Author(s)
  Liu H, Chen L, Liu J, Meng H, Zhang R, Ma L, Wu L, Yu S, Shi F, Li Y, Zhang L, Wang L, Feng S, Zhang Q, Peng Y, Wu Q, Liu C, Chang X, Yang L, Uemura Y, Yu X, Liu T.
- Journal Title
  
  Cancer Lett.
  
  Volume: 411 Pages: 182-190
- DOI
  10.1016/j.canlet.2017.09.022
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10717, KAKENHI-PROJECT-17K10806
[Journal Article] Hepatocellular carcinoma cell sensitivity to Vg9Vd2 T lymphocyte-mediated killing is increased by zoledronate.2016
- Author(s)
  Sugai S, Yoshikawa T, Iwama T, Tsuchiya N, Ueda N, Fujinami N, Shimomura M, Zhang R, Kaneko S, Uemura Y, Nakatsura T.
- Journal Title
  
  Int J Oncol.
  
  Volume: 48 (5) Issue: 5 Pages: 1794-1804
- DOI
  10.3892/ijo.2016.3403
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462078, KAKENHI-PROJECT-15H06881, KAKENHI-PROJECT-26670578, KAKENHI-PROJECT-26861133, KAKENHI-PROJECT-26293357
[Journal Article] Vaccination with liposome-coupled glypican-3-derived epitope peptide stimulates cytotoxic T lymphocytes and inhibits GPC3-expressing tumor growth in mice.2016
- Author(s)
  Iwama T, Uchida T, Sawada Y, Tsuchiya N, Sugai S, Fujinami N, Shimomura M, Yoshikawa T, Zhang R, Uemura Y, Nakatsura T.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 469(1) Issue: 1 Pages: 138-43
- DOI
  10.1016/j.bbrc.2015.11.084
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H06881, KAKENHI-PROJECT-26861133, KAKENHI-PROJECT-26462078
[Journal Article] BCR-ABL-specific CD4+ T-helper cells promote the priming of antigen-specific cytotoxic T cells via dendritic cells2016
- Author(s)
  Ueda N, Zhang R, Tatsumi M, Liu TY, Kitayama S, Yasui Y, Sugai S, Iwama T, Senju S, Okada S, Nakatsura T, Kuzushima K, Kiyoi H, Naoe T, Kaneko S, Uemura Y.
- Journal Title
  
  Cell Mol Immunol.
  
  Volume: - Issue: 1 Pages: 15-26
- DOI
  10.1038/cmi.2016.7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06881, KAKENHI-PROJECT-26293357, KAKENHI-PROJECT-26462078, KAKENHI-PROJECT-16H05194
[Journal Article] Cellular Adjuvant Properties, Direct Cytotoxicity of Re-differentiated Va24 Invariant NK T-like Cells from Human Induced Pluripotent Stem Cells2016
- Author(s)
  Kitayama S, Zhang R, Liu TY, Ueda N, Iriguchi S, Yasui Y, Kawai Y, Tatsumi M, Hirai N, Mizoro Y, Iwama T, Watanabe A, Nakanishi M, Kuzushima K, Uemura Y, Kaneko S
- Journal Title
  
  Stem Cell Reports
  
  Volume: 6 Issue: 2 Pages: 213-227
- DOI
  10.1016/j.stemcr.2016.01.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18445, KAKENHI-PROJECT-15H04655, KAKENHI-PROJECT-15H06881, KAKENHI-PROJECT-26670578, KAKENHI-PROJECT-26293357, KAKENHI-PROJECT-26462078
[Journal Article] Generation of mouse pluripotent stem cell-derived proliferating myeloid cells as an unlimited source of functional antigen-presenting cells2015
- Author(s)
  Zhang R, Liu T, Senju S, Haruta M, Hirosawa N, Suzuki M, Tatsumi M, Ueda N, Maki H, Nakatsuka R, Matsuoka Y, Sasaki Y, Tsuzuki S, Nakanishi H, Araki R, Abe M, Akatsuka Y, Sakamoto Y, Sonoda Y, Nishimura Y, Kuzushima K, Uemura Y
- Journal Title
  
  Cancer Immunol Res
  
  Volume: 印刷中 Issue: 6 Pages: 668-677
- DOI
  10.1158/2326-6066.cir-14-0117
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24108006, KAKENHI-PROJECT-26462078, KAKENHI-PROJECT-25462607, KAKENHI-PROJECT-26290057
[Journal Article] Generation of mouse pluripotent stem cell-derived proliferating myeloid cells as an unlimited source of functional antigen-presenting cells.2015
- Author(s)
  Zhang R., Liu T., Senju S., Haruta M., Hirosawa N., Suzuki M., Tatsumi M., Ueda N., Maki H., Nakatsuka R, Matsuoka Y., Sasaki Y., Tsuzuki S., Nakanishi H., Araki R., Abe M., Akatsuka Y., Sakamoto Y., Sonoda Y., Nishimura Y., Kuzushima K. and Uemura Y.
- Journal Title
  
  Cancer Immunol. Res.
  
  Volume: Feb11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462078
[Journal Article] Generation of mouse pluripotent stem cell-derived proliferating myeloid cells as an unlimited source of functional antigen-presenting cells.2015
- Author(s)
  Zhang R., Liu T., Senju S., Haruta M., Hirosawa N., Suzuki M., Tatsumi M., Ueda N., Maki H., Nakatsuka R, Matsuoka Y., Sasaki Y., Tsuzuki S., Nakanishi H., Araki R., Abe M., Akatsuka Y., Sakamoto Y., Sonoda Y., Nishimura Y., Kuzushima K. and Uemura Y.
- Journal Title
  
  Cancer Immunol. Res.
  
  Volume: Feb11 Pages: 0117-0117
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25861253
[Journal Article] iNKT細胞と樹状細胞の相互作用によるIL-27/osteopontin産生制御2014
- Author(s)
  張エイ, 劉天懿, 鈴木元晴, 廣澤成美, 坂本安, 葛島清隆, 植村靖史
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 61 Pages: 158-163
- Data Source
  KAKENHI-PROJECT-26462078
[Journal Article] iNKT細胞による樹状細胞の機能修飾2014
- Author(s)
  張エイ, 鈴木元晴, 上田格弘, 巽美奈子, 劉天懿, 葛島清隆, #植村靖史
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 62 Pages: 307-313
- NAID
  40020210773
- Data Source
  KAKENHI-PROJECT-25861253
[Journal Article] iNKT細胞による樹状細胞の機能修飾2014
- Author(s)
  張エイ, 鈴木元晴, 上田格弘, 巽美奈子, 劉天懿, 葛島清隆, 植村靖史
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 62 Pages: 303-313
- NAID
  40020210773
- Data Source
  KAKENHI-PROJECT-26462078
[Journal Article] iNKT細胞と樹状細胞の相互作用によるIL-27/osteopontin産生制御2014
- Author(s)
  張エイ, 劉天懿, 鈴木元晴, 廣澤成美, 坂本安, 葛島清隆, 植村靖史
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 61 Pages: 158-163
- Data Source
  KAKENHI-PROJECT-25861253
[Journal Article] iNKT細胞と樹状細胞の相互作用によるIL-27/osteopontin産生制御2014
- Author(s)
  張エイ, 劉天懿, 鈴木元晴, 廣澤成美, 坂本安, 葛島清隆, 植村靖史
- Journal Title
  
  臨床免疫
  
  Volume: 61 No.2 Pages: 158-163
- Data Source
  KAKENHI-PROJECT-25861253
[Presentation] iPS細胞由来IFN産生ミエロイド細胞を用いたがん免疫療法 Cancer immunotherapy using iPS cell-derived IFN-producing myeloid cells2021
- Author(s)
  植村靖史、福田恭子
- Organizer
  日本再生医療学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09186
[Presentation] Type I interferon-delivery by iPSC-derived myeloid cells elicits antitumor immunity via XCR1+ dendritic cells2019
- Author(s)
  Zhang R, Tsuchiya N, Liu T, Kubo Y, Miyashita A, Fukushima S, Ihn H, Senju S, Endo I, Nakatsura T, Uemura Y.
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10717
[Presentation] 人工多能性幹細胞に由来するプロフェッショナル抗原提示細胞を用いた新規がんワクチン療法の開発2019
- Author(s)
  真島宏聡, 張エイ, 小林剛, 岩間達章, 大段秀樹, 中面哲也, 植村靖史
- Organizer
  第23回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-17K10717
[Presentation] Type I interferon-delivery by iPSC-derived myeloid cells elicits antitumor immunity via XCR1+ dendritic cells.2019
- Author(s)
  Fukuda K, Tsuchiya N, Liu T, Kubo Y, Miyashita A, Fukushima S, Ihn H, Senju S, Endo I, Nakatsura T, Uemura Y
- Organizer
  17th International Congress of Immunology, Beijing China
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10806
[Presentation] Type I interferon-delivery by iPSC-derived myeloid cells elicits antitumor immunity via XCR1+ dendritic cells.2019
- Author(s)
  Fukuda K, Tsuchiya N, Liu T, Kubo Y, Miyashita A, Fukushima S, Ihn H, Senju S, Endo I, Nakatsura T, Uemura Y
- Organizer
  17th International Congress of Immunology, Beijing China
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10717
[Presentation] Type I interferon-delivery by iPSC-derived myeloid cells elicits antitumor immunity via XCR1+ dendritic cells2019
- Author(s)
  Zhang R, Tsuchiya N, Liu T, Kubo Y, Miyashita A, Fukushima S, Ihn H, Senju S, Endo I, Nakatsura T, Uemura Y.
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10806
[Presentation] iPSCに由来するプロフェッショナル抗原提示細胞を用いた新規がんワクチン療法の開発2019
- Author(s)
  真島宏聡, 張エイ, 小林剛岩間達章, 大段秀樹, 中面哲也, 植村靖史
- Organizer
  第40回癌免疫外科研究会
- Data Source
  KAKENHI-PROJECT-17K10717
[Presentation] iPSCに由来するプロフェッショナル抗原提示細胞を用いた新規がんワクチン療法の開発2019
- Author(s)
  真島宏聡, 張エイ, 小林剛岩間達章, 大段秀樹, 中面哲也, 植村靖史
- Organizer
  第40回癌免疫外科研究会
- Data Source
  KAKENHI-PROJECT-17K10806
[Presentation] Generation of proliferating professional antigen-presenting cells from induced pluripotent stem cells for cancer immunotherapy2019
- Author(s)
  Mashima H, Zhang R, Kobayashi T, Liu T, Iwama T, Ohdan H, Nakatsura T, Uemura Y.
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10806
[Presentation] Generation of proliferating professional antigen-presenting cells from induced pluripotent stem cells for cancer immunotherapy2019
- Author(s)
  Mashima H, Zhang R, Kobayashi T, Liu T, Iwama T, Ohdan H, Nakatsura T, Uemura Y.
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10717
[Presentation] 人工多能性幹細胞に由来するプロフェッショナル抗原提示細胞を用いた新規がんワクチン療法の開発2019
- Author(s)
  真島宏聡, 張エイ, 小林剛, 岩間達章, 大段秀樹, 中面哲也, 植村靖史
- Organizer
  第23回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-17K10806
[Presentation] Type 1 IFN-delivery by myeloid cells from induced pluripotent stem cells elicits systemic antitumor immunity via dendritic cells2018
- Author(s)
  Rong Zhang, Nobuhiro Tsuchiya, Tianyi Liu, Yosuke Kubo, Satoshi Nakahara, Azusa Miyashita, Satoshi Fukushima, Hironobu Ihn, Satoru Senju, Itaru Endo, Tetsuya Nakatsura, Yasushi Uemura
- Organizer
  日本免疫学会
- Data Source
  KAKENHI-PROJECT-17K10806
[Presentation] 人工多能性幹細胞に由来する1型IFN産生ミエロイド細胞を用いたがん免疫療法2018
- Author(s)
  張エイ, 土屋伸広, 得光友美, 千住覚, 遠藤格, 中面哲也, 植村靖史
- Organizer
  癌免疫外科研究会
- Data Source
  KAKENHI-PROJECT-17K10806
[Presentation] Type 1 IFN-delivery by myeloid cells from induced pluripotent stem cells elicits systemic antitumor immunity via dendritic cells2018
- Author(s)
  Rong Zhang, Nobuhiro Tsuchiya, Tianyi Liu, Yosuke Kubo, Satoshi Nakahara, Azusa Miyashita, Satoshi Fukushima, Hironobu Ihn, Satoru Senju, Itaru Endo, Tetsuya Nakatsura, Yasushi Uemura
- Organizer
  日本免疫学会
- Data Source
  KAKENHI-PROJECT-17K10717
[Presentation] 人工多能性幹細胞に由来する1型IFN産生ミエロイド細胞を用いたがん免疫療法2018
- Author(s)
  張エイ, 土屋伸広, 得光友美, 千住覚, 遠藤格, 中面哲也, 植村靖史
- Organizer
  癌免疫外科研究会
- Data Source
  KAKENHI-PROJECT-17K10717
[Presentation] IFNα産生ミエロイド細胞を用いたがん免疫療法2017
- Author(s)
  岩間達章、土屋伸広、張エイ、得光友美、春田美和、劉天懿、吉川聡明、澤田雄、久保陽介、宮下梓、福島聡、田久保圭誉、阪上-沢野朝子、宮脇敦史、尹浩信、西村泰治、千住覚、遠藤格、中面哲也、植村靖史
- Organizer
  第21回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-17K10717
[Presentation] Induction of T cell-mediated anti-tumor immunity by type 1 IFN-producing myeloid cells2017
- Author(s)
  IWAMA Tatsuaki, TSUCHIYA Nobuhiro, ZHANG Rong, LIU Tianyi, KUBO Yosuke, MIYASHITA Azusa, FUKUSHIMA Satoshi, IHN Hironobu, ENDO Itaru, SENJU Satoru, NAKATSURA Tetsuya, UEMURA Yasushi
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10806
[Presentation] Cellular adjuvant properties and direct cytotoxicity in re-differentiated Vα24 invariant NKT cells from human induced pluripotent stem cells2017
- Author(s)
  Rong Zhang, Syuichi Kitayama, Tianyi Liu, Tatsuaki Iwama, Tetsuya Nakatsura, Shin Kaneko, Yasushi Uemura
- Organizer
  第36回　札幌国際がんシンポジウム
- Data Source
  KAKENHI-PROJECT-17K10806
[Presentation] Induction of T cell-mediated anti-tumor immunity by type 1 IFN-producing myeloid cells2017
- Author(s)
  IWAMA Tatsuaki, TSUCHIYA Nobuhiro, ZHANG Rong, LIU Tianyi, KUBO Yosuke, MIYASHITA Azusa, FUKUSHIMA Satoshi, IHN Hironobu, ENDO Itaru, SENJU Satoru, NAKATSURA Tetsuya, UEMURA Yasushi
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10717
[Presentation] Cellular adjuvant properties and direct cytotoxicity in re-differentiated Vα24 invariant NKT cells from human induced pluripotent stem cells2017
- Author(s)
  Rong Zhang, Syuichi Kitayama, Tianyi Liu, Tatsuaki Iwama, Tetsuya Nakatsura, Shin Kaneko, Yasushi Uemura
- Organizer
  第36回札幌国際がんシンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10717
[Presentation] 1型IFNを産生するiPS細胞由来ミエロイド細胞を用いたがん免疫療法2017
- Author(s)
  張エイ, 得光友美, 土屋伸広, 岩間達章, 下村真奈美, 澤田雄, 遠藤格,中面哲也, 千住覚, 植村靖史
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10806
[Presentation] IFNα産生ミエロイド細胞を用いたがん免疫療法2017
- Author(s)
  岩間達章、土屋伸広、張エイ、得光友美、春田美和、劉天懿、吉川聡明、澤田雄、久保陽介、宮下梓、福島聡、田久保圭誉、阪上-沢野朝子、宮脇敦史、尹浩信、西村泰治、千住覚、遠藤格、中面哲也、植村靖史
- Organizer
  第21回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-17K10806
[Presentation] 1型IFNを産生するiPS細胞由来ミエロイド細胞を用いたがん免疫療法2017
- Author(s)
  張エイ, 得光友美, 土屋伸広, 岩間達章, 下村真奈美, 澤田雄, 遠藤格,中面哲也, 千住覚, 植村靖史
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10717
[Presentation] Induction of CD8 T cell-mediated anti-tumor immunity by type 1 IFN-producing myeloid cell therapy2017
- Author(s)
  Tatsuaki Iwama, Nobuhiro Tsuchiya, Rong Zhang, Tianyi Liu, Miwa Haruta, Yosuke Kubo, Azusa Miyashita, Satoshi Fukushima, Hironobu Ihn, Yasuharu Nishimura, Satoru Senju, Itaru Endo, Tetsuya Nakatsura, Yasushi Uemura
- Organizer
  第36回　札幌国際がんシンポジウム
- Data Source
  KAKENHI-PROJECT-17K10806
[Presentation] Induction of CD8 T cell-mediated anti-tumor immunity by type 1 IFN-producing myeloid cell therapy2017
- Author(s)
  Tatsuaki Iwama, Nobuhiro Tsuchiya, Rong Zhang, Tianyi Liu, Miwa Haruta, Yosuke Kubo, Azusa Miyashita, Satoshi Fukushima, Hironobu Ihn, Yasuharu Nishimura, Satoru Senju, Itaru Endo, Tetsuya Nakatsura, Yasushi Uemura
- Organizer
  第36回札幌国際がんシンポジウム
- Data Source
  KAKENHI-PROJECT-17K10717
[Presentation] Cellular adjuvant properties and direct cytotoxicity in rejuvenated Vα24 invariant NKT cells from human induced pluripotent stem cells2016
- Author(s)
  ZHANG Rong, KITAYAMA Syuichi, LIU Tianyi, UEDA Norihiro, IWAMA Tatsuaki, NAKATSURA Tetsuya, KUZUSHIMA Kiyotaka, KANEKO Shin, UEMURA Yasushi
- Organizer
  第45回日本免疫学会学術総会
- Place of Presentation
  沖縄コンベンションセンター・宜野湾市
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-26462078
[Presentation] Therapeutic potential of dasatinib for acute graft versus leukemia disease2016
- Author(s)
  張エイ, 上田格弘, 喜多山秀一, 安井裕, 土屋伸広, 劉天懿, 岩間達章, 葛島清隆, 中面哲也, 清井仁 , 金子新, 植村靖史
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜・横浜市
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26462078
[Presentation] インターフェロンαを産生するiPS細胞由来増殖性ミエロイド細胞を用いたがん免疫療法2016
- Author(s)
  土屋伸広, 植村靖史, 岩間達章, 張エイ, 得光友美, 鈴木利宙, 吉川聡明, 澤田雄, 田久保圭誉, 阪上-沢野朝子, 宮脇敦史, 遠藤格, 中面哲也
- Organizer
  第20回日本がん免疫学会総会
- Place of Presentation
  大阪カンファレンスセンター＆ホテル・大阪市
- Year and Date
  2016-07-27
- Data Source
  KAKENHI-PROJECT-26462078
[Presentation] iPSC-pMCs genetically engineered to express IFNα as a potential cell medicine for cancer2016
- Author(s)
  TSUCHIYA Nobuhiro, UEMURA Yasushi, IWAMA Tatsuaki, ZHANG Rong, SUZUKI Toshihiro, YOSHIKAWA Toshiaki, SAWADA Yu, TAKUBO Keiyo, SAKAGAMI-SAWANO Asako, MIYAWAKI Atsushi, ENDO Itaru, NAKATSURA Tetsuya
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜・横浜市
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26462078
[Presentation] CD4-modification of re-differentiated BCR-ABL-specific T cells promote the priming of leukemia antigen-specific CTLs via DCs2016
- Author(s)
  上田格弘, 植村靖史, 張エイ, 喜多山秀一, 安井裕, 巽美奈子, 劉天懿, 葛島清隆, 清井仁 , 金子新
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜・横浜市
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26462078
[Presentation] Generation of BCR-ABL reactive CD4 T lymphocytes by reprograming and redifferentiation2015
- Author(s)
  Norihiro Ueda, Yasushi Uemura, Rong Zhang, Shuichi Kitayama, Yutaka Yasui, Minako Tatsumi, Tian-Yi Liu, Shiori Sugai, Kiyotaka Kuzushima, Hitoshi Kiyoi, Shin Kaneko
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場・名古屋市
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26462078
[Presentation] Regulation of IL-12 family cytokine/Osteopontin balance in DCs by ligand activation of iNKT cells.2015
- Author(s)
  Tatsuaki Iwama, Motoharu Suzuki, Tianyi Liu, Rong Zhang, Toshiaki Yoshikawa, Manami Shimomura, Tetsuya Nakatsura, Kiyotaka Kuzushima and Yasushi Uemura.
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場・名古屋市
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26462078
[Presentation] Generation of BCR-ABL Reactive CD4+ T Helper Cells By Reprograming and Redifferentiation2015
- Author(s)
  Norihiro Ueda, Yasushi Uemura, Zhang Rong, Shuichi Kitayama, Yutaka Yasui, Minako Tatsumi, Tian-Yi Liu, Kiyotaka Kuzushima, Hitoshi Kiyoi,Tomoki Naoe, Shin Kaneko
- Organizer
  57th ASH Annual Meeting and Exposition
- Place of Presentation
  Orlando, FL
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462078
[Presentation] Interaction of Va24 iNKT cells with dendritic cells increases the therapeutic efficacy of TCR-gene modified T cells2015
- Author(s)
  Rong Zhang, Yasushi Uemura, Tianyi Liu, Sachiko Okamoto, Hiroaki Ikeda, Minako Tatsumi, Mitsuhiro Takenoyama, Yoshiki Akatsuka, Seiji Okada, Junichi Mineno, Hiroshi Shiku, Kiyotaka Kuzushima
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場・名古屋市
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26462078
[Presentation] Pluripotent stem cell-derived myeloid cells expression TRAIL as a possible cell medicine for cancer2013
- Author(s)
  Hiroyuki Maki, Yasushi Uemura, Rong Zhang, Tianyi Liu, Motoharu Suzuki, Narumi Hirosawa, Kazuyoshi Takeda, Yasushi Sakamoto, Satoru Senju, Kiyotaka Kuzushima
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ（千葉市）
- Data Source
  KAKENHI-PROJECT-25861253
[Presentation] 多能性幹細胞由来の増殖性ミエロイド細胞を用いたがん免疫療法の開発2013
- Author(s)
  張エイ, 劉天懿, 千住覚, 廣澤成美, 辻村邦夫, 中西速夫, 薗田精昭, 坂本安, 西村泰治, 葛島清隆, 植村靖史
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-25861253
[Presentation] TRAILを発現する多能性幹細胞由来ミエロイド細胞を用いた細胞医薬の開発2013
- Author(s)
  牧寛之, 植村靖史, 張エイ, 竹田和由, 劉天懿, 鈴木元晴, 都築忍, 岡村文子, 赤塚美樹, 西村泰治, 千住覚, 葛島清隆
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-25861253
[Presentation] BCR-ABL特異的ヘルパーT細胞のリプログラミングとCML治療への応用
- Author(s)
  上田格弘, 植村靖史, 張エイ, 劉天懿, 巽美奈子, 安井裕, 葛島清隆, 清井仁, 金子新
- Organizer
  第18回日本がん免疫学会総会
- Place of Presentation
  ひめぎんホール・松山市
- Year and Date
  2014-07-30 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-25861253
[Presentation] Generation of BCR-ABL reactive CD4 T lymphocytes by reprograming and redifferentiation.
- Author(s)
  上田格弘, 植村靖史, 張エイ, 劉天懿, 巽美奈子, 安井裕, 葛島清隆, 清井仁, 金子新
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜　横浜市
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26462078
[Presentation] BCR-ABL特異的ヘルパーT細胞のリプログラミングとCML治療への応用
- Author(s)
  上田格弘, 植村靖史, 張エイ, 劉天懿, 巽美奈子, 安井裕, 葛島清隆, 清井仁, 金子新
- Organizer
  第18回日本がん免疫学会総会
- Place of Presentation
  ひめぎんホール　松山市
- Year and Date
  2014-07-30 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-26462078
[Presentation] Generation of BCR-ABL reactive CD4 T lymphocytes by reprograming and redifferentiation
- Author(s)
  Norihiro Ueda, Yasushi Uemura, Rong Zhang, Tian-Yi Liu, Minako Tatsumi, Yutaka Yasui, Kiyotaka Kuzushima, Hitoshi Kiyoi, Shin Kaneko
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会館　京都市
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-26462078
[Presentation] Generation of BCR-ABL reactive CD4 T lymphocytes by reprograming and redifferentiation.
- Author(s)
  上田格弘, 植村靖史, 張エイ, 劉天懿, 巽美奈子, 安井裕, 葛島清隆, 清井仁, 金子新
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜・横浜市
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25861253
[Presentation] BCR-ABL–specific T helper cells facilitate propagation of antigen-specific CTLs via DC maturation.
- Author(s)
  上田格弘, 植村靖史, 張エイ, 劉天懿, 巽美奈子, 安井裕, 葛島清隆, 清井仁, 金子新
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場　大阪市
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-26462078
[Presentation] BCR-ABL–specific T helper cells facilitate propagation of antigen-specific CTLs via DC maturation.
- Author(s)
  上田格弘, 植村靖史, 張エイ, 劉天懿, 巽美奈子, 安井裕, 葛島清隆, 清井仁, 金子　新
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場・大阪市
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-25861253
[Presentation] Generation of BCR-ABL reactive CD4 T lymphocytes by reprograming and redifferentiation
- Author(s)
  Norihiro Ueda, Yasushi Uemura, Rong Zhang, Tian-Yi Liu, Minako Tatsumi, Yutaka Yasui, Kiyotaka Kuzushima, Hitoshi Kiyoi, Shin Kaneko
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会館・京都市
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25861253

1. UEMURA Yasushi (40364781)

# of Collaborated Projects: 6 results

# of Collaborated Products: 49 results
2. KUZUSHIMA Kiyotaka (30311442)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
3. 千住覚 (50274709)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
4. FUKUSHIMA Satoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
5. KANEKO Shin

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 中西速夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 尹浩信

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 岩間達章

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 清井仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 入口翔一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 宮下梓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Fukuda Kyoko 福田 恭子

張エイ

ZHANG Rong 張 エイ

Research Projects

Research Products

Co-Researchers

Development of novel chimeric antigen receptor (CAR) macrophage therapy for solid tumors

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Cell preparation regulating the in vivo function of CAR-T cells

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Therapy for lung cancer using the genetically engineered myeloid cells producing type III IFNPrincipal Investigator

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Generation of tumor-reactive T cells from iPS cell-derived NKT cells and application for pancreatic cancer therapy

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Type I IFN-producing myeloid cells as a cell preparation for lung canerPrincipal Investigator

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Reprogramming and re-differentiation of invariant NKT cells for pancreatic cancer immunotherapy

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Application of anti-cancer effector cells that exert adjuvant effects for lung cancerPrincipal Investigator

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[Book] 実験医学 増刊2020

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[Journal Article] Immune cell therapy against disseminated melanoma by utilizing induced pluripotent stem cell-derived myeloid cell lines producing interferon-beta or interleukin-15/interleukin-15 receptor alpha2021

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[Journal Article] CD11b + DIP2A + LAG3 + cells facilitate immune dysfunction in colorectal cancer2021

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[Journal Article] Immunotherapy with 4-1BBL-Expressing iPS Cell-Derived Myeloid Lines Amplifies Antigen-Specific T Cell Infiltration in Advanced Melanoma2021

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[Journal Article] Improved safety of induced pluripotent stem cell-derived antigen-presenting cell-based cancer immunotherapy2021

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[Journal Article] Analysis of human glioma-associated co-inhibitory immune checkpoints in glioma microenvironment and peripheral blood2021

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[Journal Article] Induced pluripotent stem cell‐derived myeloid cells expressing OX40 ligand amplify antigen‐specific T cells in advanced melanoma2020

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Fukuda Kyoko 福田恭子

ZHANG Rong 張エイ

[Book] 実験医学増刊2020