Chonabayashi Kazuhisa 蝶名林和久

Researcher Number	00646010
Other IDs
Affiliation (Current)	2025: 京都大学, 医学研究科, 助教
Affiliation (based on the past Project Information) *help	2021 – 2024: 京都大学, 医学研究科, 特定病院助教 2023: 京都大学, 医学研究科, 助教 2014 – 2018: 京都大学, iPS細胞研究所, 特定研究員
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Hematology
Keywords	Principal Investigator 疾患特異的iPS細胞 / 新規治療薬 / iPS細胞 / リプログラミング / 骨髄異形成症候群 / 骨髄性腫瘍 / 遺伝性骨髄不全症候群 / Atelis症候群 / SLF1/2-SMC5/6経路 / スーパーエンハンサー … More / 転写制御領域 / EVI1活性化 / BET阻害剤 / エンハンサーハイジャック / EVI1 (MECOM) 活性化 / 非定型3q26転座型骨髄性腫瘍 / 腫瘍内多様性 / 二次性急性骨髄性白血病 / 造血前駆細胞 / MDS / 病態解明 / 血液分化異常 Less

Elucidation of the regulatory mechanism of the SLF1/2-SMC5/6 pathway in hematopoiesis and its therapeutic applicationPrincipal Investigator
- Principal Investigator
  
  蝶名林和久
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto University
Elucidation of epigenetic regulation mechanism of myeloid neoplasms with atypical 3q26 translocation toward therapeutic applicationsPrincipal Investigator
- Principal Investigator
  
  Chonabayashi Kazuhisa
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto University
Reprogramming technology revealed the genetic and functional diversity present in an individual myelodysplastic syndrome patientPrincipal Investigator
- Principal Investigator
  
  Chonabayashi Kazuhisa
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kyoto University
Search for pathogenesis and novel therapeutics of acquired myelodysplastic syndromes using reprogramming technologyPrincipal Investigator
- Principal Investigator
  
  Chonabayashi Kazuhisa
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Kyoto University

All 2019 2018 2017 2016 2015 Other

All Journal Article Presentation

[Journal Article] Escape hematopoiesis by HLA-B5401-lacking hematopoietic stem progenitor cells in men with acquired aplastic anemia.2019
- Author(s)
  Mahmoud I. Elbadry、Mizumaki Hiroki、Hosokawa Kohei、J. Luis Espinoza、Nakagawa Noriharu、Chonabayashi Kazuhisa、Yoshida Yoshinori、Katagiri Takamasa、Hosomichi Kazuyoshi、Zaimoku Yoshitaka、Imi Tatsuya、Mai Anh Thi Nguyen、Fujii Youichi、Tajima Atsushi、Ogawa Seishi、Takenaka Katsuto、Akashi Koichi、Nakao Shinji
- Journal Title
  
  Haematologica
  
  Volume: 印刷中 Issue: 10 Pages: 210856-210856
- DOI
  10.3324/haematol.2018.210856
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06502, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-16H05335, KAKENHI-PROJECT-18H02840, KAKENHI-PROJECT-16K09847, KAKENHI-PROJECT-17K19804, KAKENHI-PROJECT-17K16184, KAKENHI-PLANNED-15H05909, KAKENHI-PUBLICLY-19H05344, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-17K09007
[Journal Article] Hematopoiesis by iPSC-derived hematopoietic stem cells of aplastic anemia that escape cytotoxic T-cell attack2018
- Author(s)
  Espinoza J. Luis、Elbadry Mahmoud I.、Chonabayashi Kazuhisa、Yoshida Yoshinori、Katagiri Takamasa、Harada Kenichi、Nakagawa Noriharu、Zaimoku Yoshitaka、Imi Tatsuya、Hassanein Hassan A.、Khalifa A. Noreldin Amal、Takenaka Katsuto、Akashi Koichi、Hamana Hiroshi、Kishi Hiroyuki、Akatsuka Yoshiki、Nakao Shinji
- Journal Title
  
  Blood Adv
  
  Volume: 2 Issue: 4 Pages: 390-400
- DOI
  10.1182/bloodadvances.2017013342
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09007, KAKENHI-PLANNED-16H06499, KAKENHI-PROJECT-16H06391, KAKENHI-PROJECT-16H05335, KAKENHI-PROJECT-15K09512, KAKENHI-PROJECT-18H02840, KAKENHI-PROJECT-16K09847
[Journal Article] Reprogramming technology reveals genetic and functional diversity of subclones in myelodysplastic syndromes2017
- Author(s)
  Chonabayashi K, Yoshida Y, Takaori-Kondo A.
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 58 Issue: 7 Pages: 787-791
- DOI
  10.11406/rinketsu.58.787
- NAID
  130005907578
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09847
[Journal Article] リプログラミング技術を用いた骨髄異形成症候群の病態解明と新規治療の可能性.2015
- Author(s)
  蝶名林　和久、吉田　善紀、高折　晃史.
- Journal Title
  
  iPS細胞を用いた難病研究-臨床病態解明と創薬に向けた研究の最新知見. 遺伝子医学MOOK27号.
  
  Volume: 27 Pages: 147-151
- Data Source
  KAKENHI-PROJECT-26860727
[Journal Article] リプログラミング技術を用いた骨髄異形成症候群の病態解明と新規治療の可能性．iPS 細胞を用いた難病研究-臨床病態解明と創薬に向けた研究の最新知見2015
- Author(s)
  蝶名林和久，吉田善紀，高折晃史．
- Journal Title
  
  遺伝子医学MOOK27 号．メディカルドゥ社．
  
  Volume: 27 Pages: 147-151
- Data Source
  KAKENHI-PROJECT-26860727
[Presentation] iPS technology revealed the genetic and functional diversity present in a myelodysplastic syndrome patient.2018
- Author(s)
  Kazuhisa Chonabayashi, Akira Watanabe, Akifumi Takaori-Kondo, and Yoshinori Yoshida
- Organizer
  International Society for Stem Cell Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09847
[Presentation] iPS technology revealed the genetic and functional diversity present in a myelodysplastic syndrome patient.2018
- Author(s)
  Kazuhisa Chonabayashi, Akira Watanabe, Akifumi Takaori-Kondo, and Yoshinori Yoshida
- Organizer
  International Society for Stem Cell Research Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09847
[Presentation] iPS technology revealed the genetic and functional diversity present in a secondary AML patient2016
- Author(s)
  Kazuhisa Chonabayashi, Masahiro Kawahara, Akira Watanabe, Masahiro Nakamura, Masatoshi Nishizawa, Akifumi Takaori-Kondo, Shinya Yamanaka, Yoshinori Yoshida.
- Organizer
  The 58th Annual Meeting of the American Society of Hematology.
- Place of Presentation
  San Diego, CA
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09847
[Presentation] Generation of engraftable leukemic stem cells from iPS cells derived from a secondary AML patient2015
- Author(s)
  Kazuhisa Chonabayashi, Masahiro Kawahara, Masatoshi Nishizawa, Akifumi Takaori-Kondo, Shinya Yamanaka, and Yoshinori Yoshida
- Organizer
  The 77th Annual Meeting of the Japanese Society of Hematology.
- Place of Presentation
  Kanazawa City
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-26860727
[Presentation] Patient-specific induced pluripotent stem cells recapitulate the maturation defect of myelodysplastic syndromes.
- Author(s)
  Kazuhisa Chonabayashi, Masahiro Kawahara, Keisuke Okita, Masatoshi Nishizawa, Norimitsu Kadowaki, Akifumi Takaori-Kondo, Shinya Yamanaka, Yoshinori Yoshida.
- Organizer
  The 56th Annual Meeting of the American Society of Hematology.
- Place of Presentation
  San Francisco, CA
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-26860727
[Presentation] iPS technology revealed the genetic and functional diversity present in a single MDS patient.
- Author(s)
  Kazuhisa Chonabayashi, Masahiro Kawahara, Akira Watanabe, Naoki Amano, Keisuke Okita, Masatoshi Nishizawa, Norimitsu Kadowaki, Akifumi Takaori-Kondo, Shinya Yamanaka, Yoshinori Yoshida.
- Organizer
  The 76th Annual Meeting of the Japanese Society of Hematology.
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-26860727

1. Yoshida Yoshinori

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. HOSOMICHI Kazuyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 片桐孝和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Chonabayashi Kazuhisa 蝶名林 和久

Research Projects

Research Products

Co-Researchers

Elucidation of the regulatory mechanism of the SLF1/2-SMC5/6 pathway in hematopoiesis and its therapeutic applicationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of epigenetic regulation mechanism of myeloid neoplasms with atypical 3q26 translocation toward therapeutic applicationsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Reprogramming technology revealed the genetic and functional diversity present in an individual myelodysplastic syndrome patientPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Search for pathogenesis and novel therapeutics of acquired myelodysplastic syndromes using reprogramming technologyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Escape hematopoiesis by HLA-B5401-lacking hematopoietic stem progenitor cells in men with acquired aplastic anemia.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hematopoiesis by iPSC-derived hematopoietic stem cells of aplastic anemia that escape cytotoxic T-cell attack2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reprogramming technology reveals genetic and functional diversity of subclones in myelodysplastic syndromes2017

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] リプログラミング技術を用いた骨髄異形成症候群の病態解明と新規治療の可能性.2015

Author(s)

Journal Title

Data Source

[Journal Article] リプログラミング技術を用いた骨髄異形成症候群の病態解明と新規治療の可能性．iPS 細胞を用いた難病研究-臨床病態解明と創薬に向けた研究の最新知見2015

Author(s)

Journal Title

Data Source

[Presentation] iPS technology revealed the genetic and functional diversity present in a myelodysplastic syndrome patient.2018

Author(s)

Organizer

Data Source

[Presentation] iPS technology revealed the genetic and functional diversity present in a myelodysplastic syndrome patient.2018

Author(s)

Organizer

Data Source

[Presentation] iPS technology revealed the genetic and functional diversity present in a secondary AML patient2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Generation of engraftable leukemic stem cells from iPS cells derived from a secondary AML patient2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Patient-specific induced pluripotent stem cells recapitulate the maturation defect of myelodysplastic syndromes.

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Chonabayashi Kazuhisa 蝶名林和久