Takamatsu Kimiharu 高松公晴

Researcher Number	00649874
Affiliation (Current)	2025: 慶應義塾大学, 医学部(信濃町), 講師(非常勤)
Affiliation (based on the past Project Information) *help	2025: 慶應義塾大学, 医学部(信濃町), 講師(非常勤) 2023: 慶應義塾大学, 医学部(信濃町), 非常勤講師 2022 – 2023: 慶應義塾大学, 医学部(信濃町), 訪問研究員 2020 – 2021: 慶應義塾大学, 医学部(信濃町), 共同研究員 2019: 慶應義塾大学, 医学部(信濃町), 助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Basic Section 56030:Urology-related / Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator 薬物療法 / 免疫チェックポイント分子 / 免疫チェックポイント阻害剤 / TIGIT / LAG-3 / 腫瘍免疫微小環境 / 腎細胞癌 / TLS / 癌免疫微小環境 / 腫瘍微小環境 / 透析腎癌 / TIM-3

３次元空間シングルセル解析による腎癌免疫微小環境の解明Principal Investigator
- Principal Investigator
  
  高松公晴
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Keio University
Uncovering the biology of new immune-checkpoint molecule inhibitor and that impact for micro immune microenvironmentPrincipal Investigator
- Principal Investigator
  
  Takamatsu Kimiharu
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Keio University
Basic Research on Novel Treatment for Dialysis Kidney Cancer Using Immune Checkpoint Molecular AntibodiesPrincipal Investigator
- Principal Investigator
  
  Takamatsu Kimiharu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Keio University

All 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] Single-Cell Phenotyping of CD73 Expression Reveals the Diversity of the Tumor Immune Microenvironment and Reflects the Prognosis of Bladder Cancer2023
- Author(s)
  Izawa Mizuki、Tanaka Nobuyuki、Murakami Tetsushi、Anno Tadatsugu、Teranishi Yu、Takamatsu Kimiharu、Mikami Shuji、Kakimi Kazuhiro、Imamura Takeshi、Matsumoto Kazuhiro、Oya Mototsugu
- Journal Title
  
  Laboratory Investigation
  
  Volume: 103 Issue: 4 Pages: 100040-100040
- DOI
  10.1016/j.labinv.2022.100040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K09411, KAKENHI-PROJECT-21K19414, KAKENHI-PROJECT-22K16794, KAKENHI-PROJECT-19K07468, KAKENHI-PROJECT-20K18151, KAKENHI-PROJECT-22K16823
[Journal Article] Prognostic role of the innate immune signature CD163 and “eat me” signal calreticulin in clear cell renal cell carcinoma2023
- Author(s)
  Anno Tadatsugu、Tanaka Nobuyuki、Takamatsu Kimiharu、Hakozaki Kyohei、Kufukihara Ryohei、Baba Yuto、Takeda Toshikazu、Matsumoto Kazuhiro、Morita Shinya、Kosaka Takeo、Mikami Shuji、Nishihara Hiroshi、Mizuno Ryuichi、Oya Mototsugu
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: - Issue: 6 Pages: 1779-1788
- DOI
  10.1007/s00262-023-03369-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09411, KAKENHI-PROJECT-21K19414, KAKENHI-PROJECT-22K16794, KAKENHI-PROJECT-19K07468, KAKENHI-PROJECT-23K24476
[Journal Article] Hybridisation chain reaction-based visualisation and screening for lncRNA profiles in clear-cell renal-cell carcinoma2022
- Author(s)
  Kufukihara Ryohei、Tanaka Nobuyuki、Takamatsu Kimiharu、Niwa Naoya、Fukumoto Keishiro、Yasumizu Yota、Takeda Toshikazu、Matsumoto Kazuhiro、Morita Shinya、Kosaka Takeo、Aimono Eriko、Nishihara Hiroshi、Mizuno Ryuichi、Oya Mototsugu
- Journal Title
  
  British Journal of Cancer
  
  Volume: 127 Issue: 6 Pages: 1133-1141
- DOI
  10.1038/s41416-022-01895-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K09356, KAKENHI-PROJECT-21K19414, KAKENHI-PROJECT-22K16794, KAKENHI-PROJECT-23K24476
[Journal Article] Unique characteristics of tertiary lymphoid structures in kidney clear cell carcinoma: prognostic outcome and comparison with bladder cancer2022
- Author(s)
  Masuda Tsukasa、Tanaka Nobuyuki、Takamatsu Kimiharu、Hakozaki Kyohei、Takahashi Ryohei、Anno Tadatsugu、Kufukihara Ryohei、Shojo Kazunori、Mikami Shuji、Shinojima Toshiaki、Kakimi Kazuhiro、Tsunoda Tatsuhiko、Aimono Eriko、Nishihara Hiroshi、Mizuno Ryuichi、Oya Mototsugu
- Journal Title
  
  Journal for ImmunoTherapy of Cancer
  
  Volume: 10 Issue: 3 Pages: 1-12
- DOI
  10.1136/jitc-2021-003883
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03792, KAKENHI-PROJECT-21K19414, KAKENHI-PROJECT-21K07156, KAKENHI-PROJECT-22K16794, KAKENHI-PROJECT-19K07468
[Journal Article] Profiling the inhibitory receptors LAG-3, TIM-3, and TIGIT in renal cell carcinoma reveals malignancy2021
- Author(s)
  Kimiharu Takamatsu
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 5547-5547
- DOI
  10.1038/s41467-021-25865-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16807, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-19H03792, KAKENHI-PROJECT-19K07468, KAKENHI-PROJECT-21K19414
[Presentation] Uncovering LAG-3 related tumor immunology in renal cell carcinoma and pan-cancer evaluation.2023
- Author(s)
  Kimiharu Takamatsu
- Organizer
  American Society of Clinical Oncology Annual meeting　2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16794
[Presentation] Novel prognostification model for clear cell renal cell carcinoma: Proposing the immune-based clustering algorithm using future immune-checkpoint targets2020
- Author(s)
  Takamatsu Kimiharu
- Organizer
  114th American Urological Association Annual Meeting: Washington D.C., USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16807
[Presentation] The change of serum C-reactive protein levels during molecular-targeted treatments could predict the response to anti-PD-1 treatment in metastatic renal cell carcinoma patients2020
- Author(s)
  Takamatsu Kimiharu
- Organizer
  American Society of Clinical Oncology Annual meeting　2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16807
[Presentation] Xp11.2転座型腎細胞癌における腫瘍周囲微小免疫環境の評価2020
- Author(s)
  高松公晴
- Organizer
  第29回日本小児泌尿器科学会
- Data Source
  KAKENHI-PROJECT-19K16807

1. TANAKA Nobuyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
2. 大家基嗣

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. 久冨木原良平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 三上修治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 水野隆一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 案納忠譜

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takamatsu Kimiharu 高松 公晴

Research Projects

Research Products

Co-Researchers

３次元空間シングルセル解析による腎癌免疫微小環境の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Uncovering the biology of new immune-checkpoint molecule inhibitor and that impact for micro immune microenvironmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Basic Research on Novel Treatment for Dialysis Kidney Cancer Using Immune Checkpoint Molecular AntibodiesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Single-Cell Phenotyping of CD73 Expression Reveals the Diversity of the Tumor Immune Microenvironment and Reflects the Prognosis of Bladder Cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prognostic role of the innate immune signature CD163 and “eat me” signal calreticulin in clear cell renal cell carcinoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hybridisation chain reaction-based visualisation and screening for lncRNA profiles in clear-cell renal-cell carcinoma2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Unique characteristics of tertiary lymphoid structures in kidney clear cell carcinoma: prognostic outcome and comparison with bladder cancer2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Profiling the inhibitory receptors LAG-3, TIM-3, and TIGIT in renal cell carcinoma reveals malignancy2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] Uncovering LAG-3 related tumor immunology in renal cell carcinoma and pan-cancer evaluation.2023

Author(s)

Organizer

Data Source

[Presentation] Novel prognostification model for clear cell renal cell carcinoma: Proposing the immune-based clustering algorithm using future immune-checkpoint targets2020

Author(s)

Organizer

Data Source

[Presentation] The change of serum C-reactive protein levels during molecular-targeted treatments could predict the response to anti-PD-1 treatment in metastatic renal cell carcinoma patients2020

Author(s)

Organizer

Data Source

[Presentation] Xp11.2転座型腎細胞癌における腫瘍周囲微小免疫環境の評価2020

Author(s)

Organizer

Data Source

Takamatsu Kimiharu 高松公晴