Tomizawa Shinichi 富澤信一

… Alternative Names

TOMIZAWA Shinichi 富澤信一

Less

Researcher Number	00704628
Other IDs
Affiliation (Current)	2025: 横浜市立大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2019 – 2025: 横浜市立大学, 医学部, 講師 2014 – 2018: 横浜市立大学, 医学部, 助教
Review Section/Research Field	Principal Investigator General anatomy (including histology/embryology) / Basic Section 56030:Urology-related / Transformative Research Areas, Section (III) Except Principal Investigator Medium-sized Section 45:Biology at organismal to population levels and anthropology, and related fields / Medium-sized Section 44:Biology at cellular to organismal levels, and related fields / Basic Section 48010:Anatomy-related
Keywords	Principal Investigator 幹細胞 / エピジェネティクス / 精子形成 / 生殖細胞 / クロマチン / 発現制御 / 細胞・組織 / 解剖学 / 分化 / 遺伝子 … More / ヒストン修飾 / シングルセル / シングルセル解析 / エピゲノム / 不妊症 / Tsga8 / Kmt2b / 不妊 / ゲノム / 精子幹細胞 / 発生 / 細胞分化 / 幹細胞分化 / 遺伝子発現制御 / クロモセンター / ヒストン … More Except Principal Investigator 生殖細胞 / 精巣 / 幹細胞 / エピジェネティクス / シングルセル解析 / 霊長類 / ヒト / DNAメチル化確立 / エピゲノム / ヒストン修飾 / 精子幹細胞 / 精子形成 / シングルセル / 配偶子 / 精原細胞 / 精子形成細胞 / 組織幹細胞 Less

生殖細胞プライミングのエピコードPrincipal Investigator
- Principal Investigator
  
  富澤信一
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Yokohama City University
ヒト雄性生殖細胞におけるDNAメチル化確立の解析
- Principal Investigator
  
  渡部聡朗
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Fund for the Promotion of Joint International Research (International Collaborative Research)
- Review Section
  
  Medium-sized Section 45:Biology at organismal to population levels and anthropology, and related fields
- Research Institution
  National Center for Child Health and Development
精子形成を支える幹細胞亜集団分化メカニズムPrincipal Investigator
- Principal Investigator
  
  富澤信一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Yokohama City University
Epigenomic regulation and its role in mechanisms of infertilityPrincipal Investigator
- Principal Investigator
  
  Tomizawa Shinichi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Yokohama City University
Identification and dynamic analysis of true stem cells in testicular stem cells using the latest single cell analysis method
- Principal Investigator
  
  OHBO Kazuyuki
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Yokohama City University
Analysis of epigenome infertiity mechanism by the state-of-art single cell and ultrtrace histone modification methods
- Principal Investigator
  
  OHBO Kazuyuki
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
- Research Institution
  Yokohama City University
Identification of genes required for spermatogonial stem cell differentiationPrincipal Investigator
- Principal Investigator
  
  Tomizawa Shinichi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Yokohama City University
Role of chromocenter formation in cellular differentiationPrincipal Investigator
- Principal Investigator
  
  TOMIZAWA Shinichi
- Project Period (FY)
  2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Yokohama City University
The role of nuclear structure and an epigenetic switch in spermatogonial stem cell differentiationPrincipal Investigator
- Principal Investigator
  
  TOMIZAWA Shinichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Yokohama City University

All 2024 2023 2022 2021 2019 2018 2017 2016 2015 Other

All Journal Article Presentation

[Journal Article] Tsga8 is required for spermatid morphogenesis and male fertility in mice2021
- Author(s)
  Kobayashi Yuki、Tomizawa Shin-ichi、Ono Michio、Kuroha Kazushige、Minamizawa Keisuke、Natsume Koji、Dizdarevic Selma、Dockal Ivana、Tanaka Hiromitsu、Kawagoe Tatsukata、Seki Masahide、Suzuki Yutaka、Ogonuki Narumi、Inoue Kimiko、Matoba Shogo、Anastassiadis Konstantinos、Mizuki Nobuhisa、Ogura Atsuo、Ohbo Kazuyuki
- Journal Title
  
  Development
  
  Volume: 148 Issue: 8
- DOI
  10.1242/dev.196212
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07228, KAKENHI-PROJECT-20K09543, KAKENHI-PLANNED-19H05758, KAKENHI-PROJECT-18H02359, KAKENHI-PROJECT-19K23831, KAKENHI-PUBLICLY-20H04934, KAKENHI-PROJECT-19K07250, KAKENHI-PROJECT-19KK0183, KAKENHI-PROJECT-16H06279, KAKENHI-PUBLICLY-20H05370, KAKENHI-PROJECT-23K20298
[Journal Article] Maintenance DNA methylation in pre-meiotic germ cells regulates meiotic prophase by facilitating homologous chromosome pairing2021
- Author(s)
  Takada Yuki、Yaman-Deveci Ruken、Shirakawa Takayuki、Sharif Jafar、Tomizawa Shin-ichi、Miura Fumihito、Ito Takashi、Ono Michio、Nakajima Kuniko、Koseki Yoko、Shiotani Fuyuko、Ishiguro Kei-ichiro、Ohbo Kazuyuki、Koseki Haruhiko
- Journal Title
  
  Development
  
  Volume: 148 Issue: 10
- DOI
  10.1242/dev.194605
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06642, KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-19K07250, KAKENHI-PROJECT-19KK0183, KAKENHI-PUBLICLY-20H05370
[Journal Article] Kmt2b conveys monovalent and bivalent H3K4me3 in spermatogonial stem cells at germline and embryonic promoters2018
- Author(s)
  Tomizawa S, Kobayashi Y, Shirakawa T, Watanabe K, Mizoguchi K, Hoshi I, Nakajima K, Nakabayashi J, Singh S, Dahl A, Alexopoulou D, Seki M, Suzuki Y, Royo H, Peters6, A. H.F.M, Anastassiadis K, Stewart A.F. and Ohbo K
- Journal Title
  
  Development
  
  Volume: 145 Issue: 23
- DOI
  10.1242/dev.169102
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08156, KAKENHI-PROJECT-17K15549, KAKENHI-PROJECT-16H06279
[Journal Article] Epigenetic regulation in stem cell development, cell fate conversion, and reprogramming.2015
- Author(s)
  Kazuyuki Ohbo, Shin-ichi Tomizawa
- Journal Title
  
  Biomolecular Concepts
  
  Volume: 6 Issue: 1 Pages: 1-9
- DOI
  10.1515/bmc-2014-0036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860137
[Journal Article] DNA methylation and gene expression dynamics during spermatogonial stem cell differentiation in the early postnatal mouse testis.2015
- Author(s)
  Kubo N, Toh H, Shirane K, Shirakawa T, Kobayashi H, Sato T, Sone H, Sato Y, Tomizawa S, Tsurusaki Y, Shibata H, Saitsu H, Suzuki Y, Matsumoto N, Suyama M, Kono T, Ohbo K, Sasaki H.
- Journal Title
  
  BMC Genomics.
  
  Volume: 16 Issue: 1 Pages: 624-624
- DOI
  10.1186/s12864-015-1833-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19660, KAKENHI-PROJECT-26860137, KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118007, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112010, KAKENHI-PROJECT-15H05579, KAKENHI-PROJECT-14J04310, KAKENHI-PLANNED-25114004
[Presentation] 精子幹細胞分化を制御するエピジェネティックな機構の解析2024
- Author(s)
  大保和之, 南澤恵佑、尾野道男、中島久仁子、Rachel Fellows、富澤信一
- Organizer
  第129回日本解剖学会総会・全国学術総会
- Data Source
  KAKENHI-PROJECT-19KK0183
[Presentation] 新規プロテアーゼインヒビターによる精子形成制御2023
- Author(s)
  富澤信一, Rachel Fellows, 尾野道男, 黒羽一誠, Ivana Dockal, 南澤恵佑, 鈴木穣, 才津浩智, 大保和之
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K09543
[Presentation] Cryptorchidism induces abnormal epigenetic and transcriptional signatures in spermatogonia2023
- Author(s)
  尾野道男, Ivana Dockal, Uros Radovic, 大保和之, 富澤信一
- Organizer
  第128回日本解剖学会総会・全国学術総会
- Data Source
  KAKENHI-PROJECT-19K07250
[Presentation] Role of a novel protease inhibitor for spermatogenesis and immune homeostasis2023
- Author(s)
  富澤信一, Rachel Fellows, 尾野道男, 黒羽一誠, Ivana Dockal, 南澤恵佑, 鈴木穣, 才津浩智, 大保和之
- Organizer
  第128回日本解剖学会総会・全国学術総会
- Data Source
  KAKENHI-PROJECT-19K07250
[Presentation] Role of a novel protease inhibitor for spermatogenesis and immune homeostasis2023
- Author(s)
  富澤信一, Rachel Fellows, 尾野道男, 黒羽一誠, Ivana Dockal, 南澤恵佑, 鈴木穣, 才津浩智, 大保和之
- Organizer
  第128回日本解剖学会総会・全国学術総会
- Data Source
  KAKENHI-PROJECT-19KK0183
[Presentation] 生殖細胞発生と胚発生のための幹細胞クロマチンプライミング2023
- Author(s)
  Tomizawa S, Kobayashi Y, Fellows R, Suzuki Y, Ogura A, Ohbo K
- Organizer
  第16回エピジェネティクス研究会年会
- Data Source
  KAKENHI-PROJECT-20K09543
[Presentation] Cryptorchidism induces abnormal epigenetic and transcriptional signatures in spermatogonia2023
- Author(s)
  尾野道男, Ivana Dockal, Uros Radovic, 大保和之, 富澤信一
- Organizer
  第128回日本解剖学会総会・全国学術総会
- Data Source
  KAKENHI-PROJECT-19KK0183
[Presentation] Role of a novel protease inhibitor for spermatogenesis and immune homeostasis2023
- Author(s)
  富澤信一, Rachel Fellows, 尾野道男, 黒羽一誠, Ivana Dockal, 南澤恵佑, 鈴木穣, 才津浩智, 大保和之
- Organizer
  第128回日本解剖学会総会全国学術集会
- Data Source
  KAKENHI-PROJECT-20K09543
[Presentation] 生殖細胞発生と胚発生のための幹細胞クロマチンプライミング2023
- Author(s)
  Tomizawa S, Kobayashi Y, Fellows R, Suzuki Y, Ogura A, Ohbo K
- Organizer
  第16回エピジェネティクス研究会年会
- Data Source
  KAKENHI-PROJECT-23K08761
[Presentation] 新規プロテアーゼインヒビターによる精子形成制御2023
- Author(s)
  富澤信一, Rachel Fellows, 尾野道男, 黒羽一誠, Ivana Dockal, 南澤恵佑, 鈴木穣, 才津浩智, 大保和之
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K08761
[Presentation] Spermatogonial chromatin priming for spermiogenic and post-fertilization development2023
- Author(s)
  富澤信一、小林裕貴、Rachel Fellows、鈴木穣、小倉淳郎、大保和之
- Organizer
  第16回エピジェネティクス研究会年会
- Data Source
  KAKENHI-PROJECT-19KK0183
[Presentation] Spermatogonial chromatin priming for spermiogenic and post-fertilization development2022
- Author(s)
  Tomizawa S, Kobayashi Y, Fellows R, Suzuki Y, Ogura A, Ohbo K
- Organizer
  The International Symposium “Totipotency and Germ Cell Development”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09543
[Presentation] Regulation of male germ cell development through KMT2B-dependent epigenetic programming2022
- Author(s)
  富澤信一、小林裕貴、Rachel Fellows、尾野道男、黒羽一誠、田中宏光、河越龍方、才津浩智、鈴木穣、水木信久、小倉淳郎、大保和之
- Organizer
  第127回日本解剖学会総会・全国集会
- Data Source
  KAKENHI-PROJECT-20K09543
[Presentation] Regulation of spermatogenesis by Kmt2b-dependent epigenome in spermatogonial stem cells2021
- Author(s)
  Yuki Kobayashi, Shin-ichi Tomizawa, Michio Ono, Kazushige Kuroha, Tatsukata Kawagoe, Masahide Seki, Yutaka Suzuki, Narumi Ogonuki, Kimiko Inoue, Shogo Matoba, Nobuhisa Mizuki, Atsuo Ogura, Kazuyuki Ohbo
- Organizer
  第14回エピジェネティクス研究会年会
- Data Source
  KAKENHI-PROJECT-20K09543
[Presentation] エピジェネティック機構を介した精子発生制御メカニズム2019
- Author(s)
  小林裕貴、尾野道男、溝口敬太、夏目幸治、富澤信一、河越龍方、水木信久、小倉淳郎、大保和之
- Organizer
  第124回日本解剖学会総会全国学術集会
- Data Source
  KAKENHI-PROJECT-17K15549
[Presentation] Kmt2b is required for spermatogenic programs through both bivalent and monovalent priming of the spermatogonial stem cell epigenome.2017
- Author(s)
  Tomizawa S, Kobayashi Y, Shirakawa T, Hoshi I, Nakajima K, Royo H, Nakamura Y, Peters AHFM, Anastassiadis K, Stewart AF, Yoshida S, Ohbo K
- Organizer
  The International Research Symposium on Regulation of Germ Cell Development in vivo and in vitro
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15549
[Presentation] Kmt2b is required for spermatogenesis through both bivalent and monovalent priming of the spermatogonial stem cell epigenome.2017
- Author(s)
  Tomizawa S, Kobayashi Y, Shirakawa T, Hoshi I, Nakajima K, Royo H, Peters AHFM, Anastassiadis K, Stewart AF, Ohbo K
- Organizer
  EMBO conference: Nuclear structure and dynamics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15549
[Presentation] Role of histone methyltransferase Mll2 for adult testicular germ cell differentiation.2016
- Author(s)
  Tomizawa S, Kobayashi Y, Shirakawa T, Dahl A, Alexopoulou D, Anastassiadis K, Stewart AF, Ohbo K
- Organizer
  Gordon Research Conference, Chromatin Structure & Function
- Place of Presentation
  Les Diablerets (スイス)
- Year and Date
  2016-05-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860137
[Presentation] Kmt2b regulates spermatogonial stem cell differentiation and marks primed genes for developmental potential.2016
- Author(s)
  Tomizawa S, Kobayashi Y, Shirakawa T, Peters AHFM, Anastassiadis K, Stewart AF, Ohbo K
- Organizer
  EMBO Conference: From Functional Genomics to Systems Biology
- Place of Presentation
  Heidelberg (ドイツ)
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860137
[Presentation] Role of histone methyltransferase Mll2 for male germ cell development
- Author(s)
  Shin-ichi Tomizawa, Takayuki Shirakawa, Konstantinos Anastassiadis, A. Francis Stewart, Kazuyuki Ohbo
- Organizer
  Keyston Symposia, Transcriptional and Epigenetic Influences on Stem Cell States
- Place of Presentation
  Colorado, USA
- Year and Date
  2015-03-23 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26860137

1. OHBO Kazuyuki (70250751)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. ITOH Takashi (90201326)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 尾野道男 (50264601)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 鈴木絢子 (00770348)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 渡部聡朗 (40715405)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 首浦武作志 (20827977)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 黒羽一誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 高田幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 鶴崎美徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tomizawa Shinichi 富澤 信一

TOMIZAWA Shinichi 富澤 信一

Research Projects

Research Products

Co-Researchers

生殖細胞プライミングのエピコードPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ヒト雄性生殖細胞におけるDNAメチル化確立の解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

精子形成を支える幹細胞亜集団分化メカニズムPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Epigenomic regulation and its role in mechanisms of infertilityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification and dynamic analysis of true stem cells in testicular stem cells using the latest single cell analysis method

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of epigenome infertiity mechanism by the state-of-art single cell and ultrtrace histone modification methods

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of genes required for spermatogonial stem cell differentiationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of chromocenter formation in cellular differentiationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of nuclear structure and an epigenetic switch in spermatogonial stem cell differentiationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Tsga8 is required for spermatid morphogenesis and male fertility in mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Maintenance DNA methylation in pre-meiotic germ cells regulates meiotic prophase by facilitating homologous chromosome pairing2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Kmt2b conveys monovalent and bivalent H3K4me3 in spermatogonial stem cells at germline and embryonic promoters2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Epigenetic regulation in stem cell development, cell fate conversion, and reprogramming.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] DNA methylation and gene expression dynamics during spermatogonial stem cell differentiation in the early postnatal mouse testis.2015

Tomizawa Shinichi 富澤信一

TOMIZAWA Shinichi 富澤信一