YAMAMOTO Hiroyuki 山元裕之

Researcher Number	00710170
Affiliation (based on the past Project Information) *help	2021 – 2023: 九州大学, 環境発達医学研究センター, 特任助教 2017 – 2018: 九州大学, 環境発達医学研究センター, 特任助教 2013 – 2016: 九州大学, 環境発達医学研究センター, 学術研究員
Review Section/Research Field	Principal Investigator Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related
Keywords	Principal Investigator 遺伝子治療 / ウイルスベクター / 原発性免疫不全症 / CD34陽性造血幹細胞 / CD34陽性細胞 / BTK遺伝子 / アデノ・アデノ随伴ウイルスハイブリッドベクター / 遺伝子変異修復 Except Principal Investigator 自己炎症 / 分化誘導 … More / オルガノイド / 網膜 / 単球 / 遺伝性自己炎症性疾患 / iPS細胞 / 網膜オルガノイド / ぶどう膜炎 / 周期性発熱 / ADP-heptose / ALPK1 / 自己炎症性疾患 / ROSAH症候群 / 人工ヌクレアーゼ / 遺伝子治療 / 腸内細菌叢網羅的解析 / 小児アトピー性皮膚炎 / 網羅的解析 / 腸内細菌叢 / 臍帯血 / アトピー性皮膚炎 / 小児 Less

X連鎖性無ガンマグロブリン血症に対する新規遺伝子治療法の開発と安全性評価の検討Principal Investigator
- Principal Investigator
  
  山元裕之
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kyushu University
The study of the pathogenesis and possible treatment of ROSAH syndrome, a novel inherited autoinflammatory disease caused by ALPK1 gene mutation.
- Principal Investigator
  
  Ishimura Masastaka
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kyushu University
Development of new gene therapy for primary immunodeficiencies by suppressing non-specific genetic modificationsPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Hiroyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kyushu University
Development of new gene-repair therapy for primary immunodeficiencies with artificial nuclease
- Principal Investigator
  
  HARA Toshiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Fukuoka Children’s Hospital
  Kyushu University
BTK gene repair by homologous recombination using a helper-dependent adenovirus/adeno-associated virus hybrid vectorPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Hiroyuki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kyushu University
小児アトピー性皮膚炎発症・経過と腸内細菌叢網羅的解析結果との関連の解明
- Principal Investigator
  
  住江愛子
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyushu University

All 2017 2016

All Journal Article Presentation

[Journal Article] BTK gene targeting by homologous recombination using a helper-dependent adenovirus/adeno-associated virus hybrid vector.2016
- Author(s)
  Yamamoto H, Ishimura M, Ochiai M, Takada H, Kusuhara K, Nakatsu Y, Tsuzuki T, Mitani K, Hara T.
- Journal Title
  
  Gene Ther
  
  Volume: 23 Issue: 2 Pages: 205-13
- DOI
  10.1038/gt.2015.91
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09655, KAKENHI-PROJECT-26340025, KAKENHI-PROJECT-15K15393, KAKENHI-PROJECT-15K19623, KAKENHI-PUBLICLY-15H00897, KAKENHI-PLANNED-24108009, KAKENHI-PROJECT-26860811
[Presentation] BTK Gene Targeting by Homologous Recombination Using a Helper-Dependent Adenovirus/Adeno-Associated Virus Hybrid Vector and CRISPR/Cas9 System2017
- Author(s)
  Hiroyuki Yamamoto, Hidetoshi Takada, Masataka Ishimura, Masayuki Ochiai, Toshiro Hara, Shouichi Ohga
- Organizer
  The 8th JSH International Symposium 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15393
[Presentation] BTK gene targeting by homologous recombination using a helper-dependent adenovirus/adeno-associated virus hybrid vector2016
- Author(s)
  山元裕之
- Organizer
  第２７回福岡国際母子総合研究シンポジウム
- Place of Presentation
  JR 博多シティ（福岡県福岡市）
- Year and Date
  2016-08-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15393

1. HARA Toshiro (40150445)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. Ishimura Masastaka (10448417)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 住江愛子 (80335968)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 野崎高史 (80635821)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 楠田剛 (90710533)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 諸隈誠一 (50380639)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 古江増隆 (70134583)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 高田英俊 (70294931)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 八幡信代 (90315812)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 園田素史 (00748006)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YAMAMOTO Hiroyuki 山元 裕之

Research Projects

Research Products

Co-Researchers

X連鎖性無ガンマグロブリン血症に対する新規遺伝子治療法の開発と安全性評価の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The study of the pathogenesis and possible treatment of ROSAH syndrome, a novel inherited autoinflammatory disease caused by ALPK1 gene mutation.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of new gene therapy for primary immunodeficiencies by suppressing non-specific genetic modificationsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of new gene-repair therapy for primary immunodeficiencies with artificial nuclease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

BTK gene repair by homologous recombination using a helper-dependent adenovirus/adeno-associated virus hybrid vectorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

小児アトピー性皮膚炎発症・経過と腸内細菌叢網羅的解析結果との関連の解明

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] BTK gene targeting by homologous recombination using a helper-dependent adenovirus/adeno-associated virus hybrid vector.2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] BTK Gene Targeting by Homologous Recombination Using a Helper-Dependent Adenovirus/Adeno-Associated Virus Hybrid Vector and CRISPR/Cas9 System2017

Author(s)

Organizer

Data Source

[Presentation] BTK gene targeting by homologous recombination using a helper-dependent adenovirus/adeno-associated virus hybrid vector2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

YAMAMOTO Hiroyuki 山元裕之